ZA843995B - Antibiotic compounds derived from cephalosporins,process for their production and pharmaceutical compositions containing them - Google Patents

Antibiotic compounds derived from cephalosporins,process for their production and pharmaceutical compositions containing them

Info

Publication number
ZA843995B
ZA843995B ZA843995A ZA843995A ZA843995B ZA 843995 B ZA843995 B ZA 843995B ZA 843995 A ZA843995 A ZA 843995A ZA 843995 A ZA843995 A ZA 843995A ZA 843995 B ZA843995 B ZA 843995B
Authority
ZA
South Africa
Prior art keywords
cephalosporins
production
pharmaceutical compositions
compositions containing
compounds derived
Prior art date
Application number
ZA843995A
Other languages
English (en)
Inventor
Ali Salhi
Dominique Olliero
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of ZA843995B publication Critical patent/ZA843995B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Professional, Industrial, Or Sporting Protective Garments (AREA)
  • Bakery Products And Manufacturing Methods Therefor (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA843995A 1983-05-27 1984-05-25 Antibiotic compounds derived from cephalosporins,process for their production and pharmaceutical compositions containing them ZA843995B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8308862A FR2546520B1 (fr) 1983-05-27 1983-05-27 Nouveaux composes antibiotiques derives des cephalosporines

Publications (1)

Publication Number Publication Date
ZA843995B true ZA843995B (en) 1984-12-24

Family

ID=9289271

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA843995A ZA843995B (en) 1983-05-27 1984-05-25 Antibiotic compounds derived from cephalosporins,process for their production and pharmaceutical compositions containing them

Country Status (27)

Country Link
US (1) US4656166A (xx)
EP (1) EP0127543B1 (xx)
JP (1) JPS59227886A (xx)
KR (1) KR910004302B1 (xx)
AT (1) ATE46339T1 (xx)
AU (1) AU570973B2 (xx)
CA (1) CA1247596A (xx)
CS (1) CS241546B2 (xx)
DD (1) DD219773A5 (xx)
DE (1) DE3479733D1 (xx)
DK (1) DK255684A (xx)
ES (1) ES532805A0 (xx)
FI (1) FI842042A (xx)
FR (1) FR2546520B1 (xx)
GR (1) GR82042B (xx)
HU (1) HU191658B (xx)
IL (1) IL71933A (xx)
MA (1) MA20126A1 (xx)
NO (1) NO163408C (xx)
NZ (1) NZ208275A (xx)
OA (1) OA07777A (xx)
PH (1) PH20389A (xx)
PL (1) PL144003B1 (xx)
PT (1) PT78635B (xx)
SU (1) SU1282817A3 (xx)
YU (1) YU90684A (xx)
ZA (1) ZA843995B (xx)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2546520B1 (fr) * 1983-05-27 1985-08-30 Sanofi Sa Nouveaux composes antibiotiques derives des cephalosporines
FR2570702B1 (fr) * 1984-09-27 1987-01-09 Sanofi Sa Derives des cephalosporines, procedes d'obtention et leur application a titre d'antibiotiques
JPS61207822A (ja) * 1985-03-12 1986-09-16 Toyota Motor Corp 吸気管長可変式吸気装置の吸気制御弁の制御方法
US4783443A (en) * 1986-03-03 1988-11-08 The University Of Chicago Amino acyl cephalosporin derivatives
US5147871A (en) * 1986-07-03 1992-09-15 Hoffmann La-Roche, Inc. Anti-bacterial cephalosporin compounds
FR2607135B1 (fr) * 1986-11-20 1989-04-28 Sanofi Sa Nouveaux derives des cephalosporines a pharmacocinetique amelioree, procede pour leur preparation et compositions pharmaceutiques les contenant
FR2621589B1 (fr) * 1987-10-08 1990-03-02 Sanofi Sa Derives des cephalosporines a pharmacocinetique amelioree, procede pour leur preparation et compositions pharmaceutiques les contenant
US5189157A (en) * 1987-06-16 1993-02-23 Hoffmann La Roche Inc. Antibacterial cephalosporin compounds
CS273349B2 (en) * 1988-03-31 1991-03-12 Hoffmann La Roche Method of cephalosporin's new derivatives production
US5336768A (en) * 1988-05-24 1994-08-09 Hoffmann-La Roche Inc. Antibacterial cephalosporin compounds
DE10134478B4 (de) * 2001-07-16 2007-10-31 Priaton Gmbh Verfahren zur Darstellung von thiazolsubstituierten β-Lactamen
FR2842523A1 (fr) * 2002-07-17 2004-01-23 Sanofi Synthelabo Derives d'acylaminothiazole, leur preparation et leur application en therapeutique

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4338438A (en) * 1970-06-16 1982-07-06 Merck & Co., Inc. Cephalosporin antibiotics
BE768844A (en) * 1971-06-22 1971-12-22 Fujisawa Pharmaceutical Co 7-(2-acyloxy-acetamido)-3-cephem-4-carboxylic acid derivs - - antibacterials
GB1425933A (en) * 1972-03-13 1976-02-25 Astra Laekemedel Ab Cephalosporins
OA05033A (fr) * 1974-07-01 1980-12-31 Rhone Poulenc Ind Nouveaux dérivés de la céphalosporine et leur préparation.
FR2342733A1 (fr) * 1976-01-14 1977-09-30 Roussel Uclaf Derives de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
DE2760123C2 (de) * 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
GR63088B (en) * 1976-04-14 1979-08-09 Takeda Chemical Industries Ltd Preparation process of novel cephalosporins
DE2716677C2 (de) * 1977-04-15 1985-10-10 Hoechst Ag, 6230 Frankfurt Cephemderivate und Verfahren zu ihrer Herstellung
US4341775A (en) * 1978-09-11 1982-07-27 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
US4409215A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical Co., Ltd. 7-Acylamino-3-substituted cephalosporanic acid derivatives and processes for the preparation thereof
FR2501209B1 (fr) * 1981-03-03 1986-07-04 Sanofi Sa Nouveaux derives des cephalosporines et medicaments antibiotiques contenant lesdits derives
FR2485540A1 (fr) * 1980-06-30 1981-12-31 Sanofi Sa Nouveaux derives antibiotiques des cephalosporines, leur procede de preparation et les medicaments en contenant
DE3177090D1 (en) * 1980-12-31 1989-09-28 Fujisawa Pharmaceutical Co 7-acylaminocephalosporanic acid derivatives and processes for the preparation thereof
FR2506307A1 (fr) * 1981-05-22 1982-11-26 Roussel Uclaf Nouveaux derives substitues de l'acide 2-(2-amino 4-thiazolyl) 2-hydroxyimino acetique et leur procede de preparation
US4396619A (en) * 1981-09-08 1983-08-02 Eli Lilly And Company Cephalosporin betaines
FR2546520B1 (fr) * 1983-05-27 1985-08-30 Sanofi Sa Nouveaux composes antibiotiques derives des cephalosporines

Also Published As

Publication number Publication date
MA20126A1 (fr) 1984-12-31
ES8502706A1 (es) 1985-01-16
IL71933A0 (en) 1984-09-30
FR2546520B1 (fr) 1985-08-30
EP0127543A2 (fr) 1984-12-05
CA1247596A (en) 1988-12-28
DK255684A (da) 1984-11-28
PL247843A1 (en) 1985-03-26
YU90684A (en) 1986-12-31
DD219773A5 (de) 1985-03-13
NZ208275A (en) 1986-11-12
EP0127543B1 (fr) 1989-09-13
NO842091L (no) 1984-11-28
ES532805A0 (es) 1985-01-16
OA07777A (fr) 1985-08-30
NO163408C (no) 1990-05-23
FI842042A (fi) 1984-11-28
FR2546520A1 (fr) 1984-11-30
DE3479733D1 (en) 1989-10-19
KR910004302B1 (ko) 1991-06-25
CS241546B2 (en) 1986-03-13
CS399784A2 (en) 1985-07-16
JPS59227886A (ja) 1984-12-21
KR840009114A (ko) 1984-12-24
PT78635B (fr) 1986-06-18
EP0127543A3 (en) 1985-11-27
IL71933A (en) 1987-11-30
GR82042B (xx) 1984-12-12
PT78635A (fr) 1984-06-01
NO163408B (no) 1990-02-12
ATE46339T1 (de) 1989-09-15
SU1282817A3 (ru) 1987-01-07
AU2858284A (en) 1984-11-29
AU570973B2 (en) 1988-03-31
DK255684D0 (da) 1984-05-24
PH20389A (en) 1986-12-10
HU191658B (en) 1987-03-30
HUT34500A (en) 1985-03-28
FI842042A0 (fi) 1984-05-22
US4656166A (en) 1987-04-07
PL144003B1 (en) 1988-04-30

Similar Documents

Publication Publication Date Title
ZA843995B (en) Antibiotic compounds derived from cephalosporins,process for their production and pharmaceutical compositions containing them
DE3275295D1 (en) Anti-srs-a carboxylic acid derivatives, processes for their production, and pharmaceutical formulation containing them
DE3363244D1 (en) Compounds, process for their preparation and their use as pharmaceutical preparations
ES8503667A1 (es) Un procedimiento para la preparacion de nuevos derivados de 2-oxo-imidazolina.
ES8401068A1 (es) Procedimiento para la preparacion de derivados de corinanteina, asi como de sus sales de adicion acida fisiologicamente inocuas.
HUT45518A (en) Process for producing 1,5-benzothiazepine derivatives and pharmaceutics comprising these compounds
IL69210A0 (en) Cephalosporin derivatives,their process of preparation and pharmaceutical compositions containing them
ES8401761A1 (es) Un procedimiento para la preparacion de derivados de 1-(3,4,5-trimetoxicinamoil)-4-aminocarboniletil-piperazina sustituidos.
DE3369846D1 (en) Bicyclic phenol ethers, process for their preparation and medicines containing these compounds