ZA8408275B - New piridine-2-ethers or pyridine-2-thioethers having a nitrogen-containing cycloaliphatic ring - Google Patents

New piridine-2-ethers or pyridine-2-thioethers having a nitrogen-containing cycloaliphatic ring

Info

Publication number
ZA8408275B
ZA8408275B ZA848275A ZA8408275A ZA8408275B ZA 8408275 B ZA8408275 B ZA 8408275B ZA 848275 A ZA848275 A ZA 848275A ZA 8408275 A ZA8408275 A ZA 8408275A ZA 8408275 B ZA8408275 B ZA 8408275B
Authority
ZA
South Africa
Prior art keywords
piridine
thioethers
pyridine
ethers
nitrogen
Prior art date
Application number
ZA848275A
Inventor
Gerhard Scheffler
Juergen Engel
Vladimir Jakovlev
Bernd Nickel
Klaus Thiemer
Original Assignee
Degussa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DE3347276 priority Critical
Application filed by Degussa filed Critical Degussa
Publication of ZA8408275B publication Critical patent/ZA8408275B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with heteroatoms or with carbon atoms having three bonds to hetero atoms, with at the most one to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/70Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/54Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D451/00Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
ZA848275A 1983-12-28 1984-10-23 New piridine-2-ethers or pyridine-2-thioethers having a nitrogen-containing cycloaliphatic ring ZA8408275B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE3347276 1983-12-28

Publications (1)

Publication Number Publication Date
ZA8408275B true ZA8408275B (en) 1985-08-28

Family

ID=6218282

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA848275A ZA8408275B (en) 1983-12-28 1984-10-23 New piridine-2-ethers or pyridine-2-thioethers having a nitrogen-containing cycloaliphatic ring

Country Status (20)

Country Link
US (1) US4643995A (en)
EP (1) EP0149088B1 (en)
JP (1) JPS60169476A (en)
KR (1) KR870000354B1 (en)
CN (1) CN85101353A (en)
AT (1) AT40131T (en)
AU (1) AU566560B2 (en)
DD (1) DD231354A5 (en)
DE (2) DE3443968A1 (en)
DK (1) DK613384A (en)
ES (1) ES8607014A1 (en)
FI (1) FI84062C (en)
GB (1) GB2152048B (en)
GR (1) GR82596B (en)
HU (1) HU194209B (en)
IL (1) IL73608A (en)
NO (1) NO164237C (en)
PT (1) PT79736B (en)
SU (1) SU1417796A3 (en)
ZA (1) ZA8408275B (en)

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IL107184A (en) * 1992-10-09 1997-08-14 Abbott Lab Heterocyclic ether compounds that enhance cognitive function
ZA9610736B (en) 1995-12-22 1997-06-27 Warner Lambert Co 2-Substituted piperidine analogs and their use as subtypeselective nmda receptor antagonists
ZA9610738B (en) 1995-12-22 1997-06-24 Warner Lambert Co Subtype selective nmda receptor ligands and the use thereof
ZA9610741B (en) 1995-12-22 1997-06-24 Warner Lambert Co 4-Substituted piperidine analogs and their use as subtype selective nmda receptor antagonists
ZA9610745B (en) * 1995-12-22 1997-06-24 Warner Lambert Co 4-Subsituted piperidine analogs and their use as subtype selective nmda receptor antagonists
US5629325A (en) * 1996-06-06 1997-05-13 Abbott Laboratories 3-pyridyloxymethyl heterocyclic ether compounds useful in controlling chemical synaptic transmission
US6437138B1 (en) 1996-06-06 2002-08-20 Abbott Laboratories 3-pyridyloxymethyl heterocyclic ether compounds useful in controlling chemical synaptic transmission
US6133253A (en) * 1996-12-10 2000-10-17 Abbott Laboratories 3-Pyridyl enantiomers and their use as analgesics
EP1357121A1 (en) * 1997-11-05 2003-10-29 Neurosearch A/S Azaring-ether deritatives and their use as nicotinic ach receptor modulators
US6632823B1 (en) * 1997-12-22 2003-10-14 Merck & Co., Inc. Substituted pyridine compounds useful as modulators of acetylcholine receptors
PE07282000A1 (en) * 1998-06-26 2000-08-21 Cocensys Inc Heterocycles 4-benzyl piperidine alkylsulfoxide and their use as subtype-selective receptor antagonists NMDA
WO2001019817A2 (en) * 1999-09-14 2001-03-22 Abbott Laboratories 3-pyrrolidinyloxy-3'-pyridyl ether compounds useful for controlling chemical synaptic transmission
DE10000739A1 (en) * 2000-01-11 2001-07-12 Merck Patent Gmbh New piperidine and piperazine derivatives which are antagonists of certain serotonin receptors, are useful in treatment of, e.g. eating disorders, stroke, anxiety or Parkinson's disease
US6436916B1 (en) 2000-10-12 2002-08-20 Alvin Guttag Ibuprofen-aspirin and hydroxymethylacylfulvene analogs
EP1467986A1 (en) 2002-01-17 2004-10-20 Eli Lilly And Company Aza-cyclic compounds as modulators of acetylcholine receptors
GB0220581D0 (en) 2002-09-04 2002-10-09 Novartis Ag Organic Compound
DK1599468T3 (en) 2003-01-14 2008-02-04 Arena Pharm Inc 1,2,3-trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prevention and treatment of disorders associated therewith such as diabetes and hyperglycemia
BRPI0411608A (en) * 2003-06-24 2006-08-08 Neurosearch As 8-aza-bicyclo [3.2.1] octane derivative, pharmaceutical composition, use of the compound, and method of treating, preventing or alleviating a disease, disorder or condition of a living animal organism
AR045047A1 (en) 2003-07-11 2005-10-12 Arena Pharm Inc Aryl and heteroaryl derivatives as modulators of metabolism trisubstituted and the prophylaxis and treatment of disorders related thereto
CA2568451A1 (en) * 2004-06-04 2005-12-22 Arena Pharmaceuticals, Inc. Substituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto
AR049401A1 (en) 2004-06-18 2006-07-26 Novartis Ag Aza-bicyclononanes
GB0415746D0 (en) 2004-07-14 2004-08-18 Novartis Ag Organic compounds
MY148521A (en) * 2005-01-10 2013-04-30 Arena Pharm Inc Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto
DOP2006000010A (en) 2005-01-10 2006-07-31 Arena Pharm Inc Process for preparing aromatic ethers
US7413805B2 (en) * 2005-02-25 2008-08-19 Fry's Metals, Inc. Preparation of metallic particles for electrokinetic or electrostatic deposition
KR20080044296A (en) * 2005-09-16 2008-05-20 아레나 파마슈티칼스, 인크. Modulators of metabolism and the treatment of disorders related thereto
GB0521508D0 (en) 2005-10-21 2005-11-30 Novartis Ag Organic compounds
GB0525673D0 (en) 2005-12-16 2006-01-25 Novartis Ag Organic compounds
GB0525672D0 (en) 2005-12-16 2006-01-25 Novartis Ag Organic compounds
US7872017B2 (en) 2006-05-19 2011-01-18 Abbott Laboratories Fused bicycloheterocycle substituted azabicyclic alkane derivatives
TW200811140A (en) * 2006-07-06 2008-03-01 Arena Pharm Inc Modulators of metabolism and the treatment of disorders related thereto
TW200811147A (en) * 2006-07-06 2008-03-01 Arena Pharm Inc Modulators of metabolism and the treatment of disorders related thereto
US8242121B2 (en) 2007-05-23 2012-08-14 Merck Sharp & Dohme Corp. Pyridyl piperidine orexin receptor antagonists
WO2010048014A1 (en) * 2008-10-21 2010-04-29 Merck Sharp & Dohme Corp. 2,4-disubstituted pyrrolidine orexin receptor antagonists
AU2009307916A1 (en) 2008-10-21 2010-04-29 Merck Sharp & Dohme Corp. 2,5-disubstituted morpholine orexin receptor antagonists
EP2350066B1 (en) 2008-10-21 2013-08-28 Merck Sharp & Dohme Corp. 2,5-disubstituted piperidine orexin receptor antagonists
AR088352A1 (en) 2011-10-19 2014-05-28 Merck Sharp & Dohme Receptor antagonists 2-4-pyridyloxy-nitrile orexin

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Also Published As

Publication number Publication date
HUT36115A (en) 1985-08-28
SU1417796A3 (en) 1988-08-15
PT79736B (en) 1986-12-30
EP0149088B1 (en) 1989-01-18
KR870000354B1 (en) 1987-03-05
GB8432162D0 (en) 1985-01-30
GB2152048B (en) 1987-11-11
DK613384A (en) 1985-06-29
DE3476205D1 (en) 1989-02-23
US4643995A (en) 1987-02-17
NO845250L (en) 1985-07-01
AT40131T (en) 1989-02-15
IL73608D0 (en) 1985-02-28
FI845126D0 (en)
FI845126A0 (en) 1984-12-27
JPS60169476A (en) 1985-09-02
EP0149088A1 (en) 1985-07-24
AU3699684A (en) 1985-07-04
KR850004755A (en) 1985-07-27
GR82596B (en) 1985-04-29
FI84062C (en) 1991-10-10
FI845126L (en) 1985-06-29
IL73608A (en) 1987-12-31
FI845126A (en)
DD231354A5 (en) 1985-12-24
GB2152048A (en) 1985-07-31
CN85101353A (en) 1986-10-15
NO164237C (en) 1990-09-12
NO164237B (en) 1990-06-05
AU566560B2 (en) 1987-10-22
ES539076D0 (en)
DE3443968A1 (en) 1985-10-31
FI84062B (en) 1991-06-28
ES8607014A1 (en) 1986-05-16
ES539076A0 (en) 1986-05-16
HU194209B (en) 1988-01-28
DK613384D0 (en) 1984-12-20
PT79736A (en) 1985-01-01

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