ZA8201123B - Imidazodiazepines - Google Patents

Imidazodiazepines

Info

Publication number
ZA8201123B
ZA8201123B ZA821123A ZA8201123A ZA8201123B ZA 8201123 B ZA8201123 B ZA 8201123B ZA 821123 A ZA821123 A ZA 821123A ZA 8201123 A ZA8201123 A ZA 8201123A ZA 8201123 B ZA8201123 B ZA 8201123B
Authority
ZA
South Africa
Prior art keywords
imidazodiazepines
Prior art date
Application number
ZA821123A
Inventor
Walter Hunkeler
Emilio Kyburz
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to CH133981 priority Critical
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ZA8201123B publication Critical patent/ZA8201123B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00
    • C07D487/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14Ortho-condensed systems
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y02A50/38Medical treatment of vector-borne diseases characterised by the agent
    • Y02A50/417Medical treatment of vector-borne diseases characterised by the agent the vector-borne disease being caused by a helminth, i.e. Helmanthiasis
    • Y02A50/423Medical treatment of vector-borne diseases characterised by the agent the vector-borne disease being caused by a helminth, i.e. Helmanthiasis the helminth being a trematode flatworm of the genus Schistosoma, i.e. Schistosomiasis or bilharziasis
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S514/00Drug, bio-affecting and body treating compositions
    • Y10S514/906Muscle relaxant
ZA821123A 1981-02-27 1982-02-19 Imidazodiazepines ZA8201123B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CH133981 1981-02-27

Publications (1)

Publication Number Publication Date
ZA8201123B true ZA8201123B (en) 1983-01-26

Family

ID=4208166

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA821123A ZA8201123B (en) 1981-02-27 1982-02-19 Imidazodiazepines

Country Status (8)

Country Link
US (4) US4352816A (en)
EP (1) EP0059387B1 (en)
JP (1) JPS57156490A (en)
AU (1) AU551756B2 (en)
CA (1) CA1173441A (en)
DE (1) DE3263632D1 (en)
DK (1) DK74482A (en)
ZA (1) ZA8201123B (en)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1173441A (en) * 1981-02-27 1984-08-28 Hoffmann-La Roche Limited Imidazodiazepines
MC1528A1 (en) * 1982-07-21 1984-04-13 Hoffmann La Roche imidazobenzodiazepines
ZW985A1 (en) * 1984-01-19 1985-08-28 Hoffmann La Roche Imidazodiazepine derivatives
ZA8801538B (en) * 1987-03-10 1988-09-12 F. Hoffmann-La Roche & Co. Aktiengesellschaft Imidazodiazepine derivatives
CA1312825C (en) * 1988-01-27 1993-01-19 F. Hoffmann-La Roche Ag Prevention or interruption of panic states with an imidazobenzodiazepine
DE3822876C2 (en) * 1988-07-06 1990-05-03 Ernst 6000 Frankfurt De Wagner
CA2015336A1 (en) * 1989-05-19 1990-11-19 F. Hoffmann-La Roche Ag Imidazodiazepines for the treatment of neurological symptoms
US20090054412A1 (en) * 2007-08-20 2009-02-26 John Alan Kemp Treatment of Sleep Disorders
WO2009024325A2 (en) * 2007-08-20 2009-02-26 Evotec Neurosciences Gmbh Treatment of sleep disorders
NZ602933A (en) 2010-04-15 2014-09-26 Seattle Genetics Inc Pyrrolobenzodiazepines used to treat proliferative diseases
NZ602932A (en) 2010-04-15 2014-08-29 Seattle Genetics Inc Targeted pyrrolobenzodiazapine conjugates
EP2514754B1 (en) * 2011-04-08 2013-08-21 King Saud University 6,7-dihydro-[1,3,4]thiadiazolo-[3,2-a][1,3]diazepin derivatives and pharmaceutical composition containing the same as neuromuscular blocker or skeletal muscle relaxant, and method for the preparation
WO2013041606A1 (en) 2011-09-20 2013-03-28 Spirogen Sàrl Pyrrolobenzodiazepines as unsymmetrical dimeric pbd compounds for inclusion in targeted conjugates
CA2850264A1 (en) 2011-10-14 2013-04-18 Spirogen Sarl Pyrrolobenzodiazepines
CN103998450B (en) 2011-10-14 2017-03-08 麦迪穆有限责任公司 Pyrrolo benzodiazepine
EP3388435A1 (en) 2011-10-14 2018-10-17 Seattle Genetics, Inc. Pyrrolobenzodiazepines and targeted conjugates
US9387259B2 (en) 2011-10-14 2016-07-12 Seattle Genetics, Inc. Pyrrolobenzodiazepines and targeted conjugates
ES2713164T3 (en) 2012-10-12 2019-05-20 Medimmune Ltd Pyrrolobenzodiazepines and conjugates thereof
JP5993093B2 (en) 2012-10-12 2016-09-14 メドイミューン・リミテッドMedImmune Limited Pyrrolo benzodiazepines and their complexes
HUE035694T2 (en) 2012-10-12 2018-05-28 Adc Therapeutics Sa Pyrrolobenzodiazepine-anti-cd22 antibody conjugates
CN105050661B (en) 2012-10-12 2018-03-30 Adc疗法责任有限公司 Pyrrolo benzodiazepine - antibody conjugate
AU2013328673B2 (en) 2012-10-12 2017-07-13 Medimmune Limited Synthesis and intermediates of pyrrolobenzodiazepine derivatives for conjugation
AU2013328625B2 (en) 2012-10-12 2016-12-15 Adc Therapeutics Sa Pyrrolobenzodiazepine-antibody conjugates
US9956299B2 (en) 2013-10-11 2018-05-01 Medimmune Limited Pyrrolobenzodiazepine—antibody conjugates
WO2015052532A1 (en) 2013-10-11 2015-04-16 Spirogen Sàrl Pyrrolobenzodiazepine-antibody conjugates
GB201317982D0 (en) 2013-10-11 2013-11-27 Spirogen Sarl Pyrrolobenzodiazepines and conjugates thereof
US9950078B2 (en) 2013-10-11 2018-04-24 Medimmune Limited Pyrrolobenzodiazepine-antibody conjugates
GB201317981D0 (en) 2013-10-11 2013-11-27 Spirogen Sarl Pyrrolobenzodiazepines and conjugates thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1600600A (en) * 1977-03-10 1981-10-21 Diamond Shamrock Chem Plasticiser compositions for use with synthetic resin polymers
CA1143728A (en) * 1979-10-04 1983-03-29 Max Gerecke Imidazodiazepine derivatives
CA1173441A (en) * 1981-02-27 1984-08-28 Hoffmann-La Roche Limited Imidazodiazepines

Also Published As

Publication number Publication date
JPS57156490A (en) 1982-09-27
EP0059387A2 (en) 1982-09-08
US4407752A (en) 1983-10-04
EP0059387B1 (en) 1985-05-08
US4352816A (en) 1982-10-05
EP0059387A3 (en) 1982-11-17
DE3263632D1 (en) 1985-06-13
DK74482A (en) 1982-08-28
AU551756B2 (en) 1986-05-08
CA1173441A1 (en)
AU8066482A (en) 1982-09-02
CA1173441A (en) 1984-08-28
US4382032A (en) 1983-05-03
US4405517A (en) 1983-09-20

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