ZA813786B - Salts of endo-8-methyl-8-syn-alky-8-azoniabicyclo-(3.2.1)-octane-3-alkylcarboxylates process for their preparation and therapeutic compositions containing them - Google Patents
Salts of endo-8-methyl-8-syn-alky-8-azoniabicyclo-(3.2.1)-octane-3-alkylcarboxylates process for their preparation and therapeutic compositions containing themInfo
- Publication number
- ZA813786B ZA813786B ZA00813786A ZA813786A ZA813786B ZA 813786 B ZA813786 B ZA 813786B ZA 00813786 A ZA00813786 A ZA 00813786A ZA 813786 A ZA813786 A ZA 813786A ZA 813786 B ZA813786 B ZA 813786B
- Authority
- ZA
- South Africa
- Prior art keywords
- azoniabicyclo
- syn
- endo
- octane
- methyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
- C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT22843/80A IT1140998B (it) | 1980-06-18 | 1980-06-18 | Sali di endo-8-metil-8-sin-alchil-8-azoniabiciclo aperta par. quadrata 3.2.1. chiusa par. quadrata-ottan-3-alchilcarbossilati, processo per la loro preparazione e composizioni terapeutiche che li contengono come principio attivo |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA813786B true ZA813786B (en) | 1982-07-28 |
Family
ID=11201066
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA00813786A ZA813786B (en) | 1980-06-18 | 1981-06-05 | Salts of endo-8-methyl-8-syn-alky-8-azoniabicyclo-(3.2.1)-octane-3-alkylcarboxylates process for their preparation and therapeutic compositions containing them |
Country Status (9)
Country | Link |
---|---|
US (1) | US4411902A (xx) |
EP (1) | EP0042365B1 (xx) |
JP (1) | JPS5728086A (xx) |
AT (1) | ATE9347T1 (xx) |
AU (1) | AU547923B2 (xx) |
CA (1) | CA1161040A (xx) |
DE (1) | DE3165993D1 (xx) |
IT (1) | IT1140998B (xx) |
ZA (1) | ZA813786B (xx) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1194343B (it) * | 1983-07-26 | 1988-09-14 | Valeas Spa | Sali di endo-8,8-dialchil-8-azoniabiciclo (3.2.1) ottan-6,7-esso-epossi-3-alchilcarbossilati,processo per la loro preparazione e composizioni terapeutiche che li contengono come principio attivo |
US4698217A (en) * | 1985-02-26 | 1987-10-06 | Mobil Oil Corporation | Crystalline silicate ZSM-58 and process for its preparation using a methyltropinium cation |
AT397962B (de) * | 1985-12-27 | 1994-08-25 | Madaus & Co Dr | Verfahren zur herstellung von azoniaspironortropanolestern |
US5770738A (en) * | 1992-03-05 | 1998-06-23 | Boehringer Ingelheim Kg | Esters of bi- and tricyclic amino alcohols, their preparation and their use in pharmaceutical compositions |
BR0007269A (pt) * | 1999-10-28 | 2001-10-16 | Isotech Illinois Inc | Isolador de mancal |
US6706726B2 (en) * | 2000-10-14 | 2004-03-16 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Anticholinergics which may be used as medicaments as well as processes for preparing them |
TW200534855A (en) * | 2004-01-13 | 2005-11-01 | Glaxo Group Ltd | Muscarinic acetylcholine receptor antagonists |
PE20060826A1 (es) * | 2004-12-06 | 2006-10-08 | Smithkline Beecham Corp | Derivado oleofinico de 8-azoniabiciclo[3.2.1]octano y combinacion farmaceutica que lo comprende |
RU2714135C1 (ru) * | 2019-11-22 | 2020-02-12 | Федеральное государственное бюджетное учреждение науки "Институт токсикологии Федерального медико-биологического агентства" | Гидрохлорид (1-метилпиперидин-4-ил)-2-пропилпентаноата, обладающий холинолитической и противосудорожной активностью |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3170927A (en) * | 1965-02-23 | O chzoh | ||
US2962499A (en) * | 1957-07-03 | 1960-11-29 | Endo Lab | Certain esters of tropine and tropinium salts |
US3145211A (en) * | 1962-01-04 | 1964-08-18 | Sterling Drug Inc | Tropyl esters of alpha-cycloalkylalkanoic acids |
-
1980
- 1980-06-18 IT IT22843/80A patent/IT1140998B/it active
-
1981
- 1981-06-03 US US06/270,008 patent/US4411902A/en not_active Expired - Lifetime
- 1981-06-05 ZA ZA00813786A patent/ZA813786B/xx unknown
- 1981-06-11 AT AT81830096T patent/ATE9347T1/de not_active IP Right Cessation
- 1981-06-11 DE DE8181830096T patent/DE3165993D1/de not_active Expired
- 1981-06-11 EP EP81830096A patent/EP0042365B1/en not_active Expired
- 1981-06-15 CA CA000379706A patent/CA1161040A/en not_active Expired
- 1981-06-18 AU AU71953/81A patent/AU547923B2/en not_active Ceased
- 1981-06-18 JP JP9310281A patent/JPS5728086A/ja active Granted
Also Published As
Publication number | Publication date |
---|---|
DE3165993D1 (en) | 1984-10-18 |
AU7195381A (en) | 1981-12-24 |
ATE9347T1 (de) | 1984-09-15 |
US4411902A (en) | 1983-10-25 |
EP0042365A1 (en) | 1981-12-23 |
EP0042365B1 (en) | 1984-09-12 |
CA1161040A (en) | 1984-01-24 |
IT1140998B (it) | 1986-10-10 |
JPS5728086A (en) | 1982-02-15 |
IT8022843A0 (it) | 1980-06-18 |
JPH0335319B2 (xx) | 1991-05-27 |
AU547923B2 (en) | 1985-11-14 |
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