ZA7806950B - Method of preventing carcinogenesis - Google Patents

Method of preventing carcinogenesis

Info

Publication number
ZA7806950B
ZA7806950B ZA786950A ZA7806950A ZA7806950B ZA 7806950 B ZA7806950 B ZA 7806950B ZA 786950 A ZA786950 A ZA 786950A ZA 7806950 A ZA7806950 A ZA 7806950A ZA 7806950 B ZA7806950 B ZA 7806950B
Authority
ZA
South Africa
Prior art keywords
preventing carcinogenesis
carcinogenesis
preventing
Prior art date
Application number
ZA786950A
Inventor
R Gander
Original Assignee
Johnson & Johnson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US05/929,094 priority Critical patent/US4323581A/en
Application filed by Johnson & Johnson filed Critical Johnson & Johnson
Publication of ZA7806950B publication Critical patent/ZA7806950B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/20Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
ZA786950A 1978-07-31 1978-12-12 Method of preventing carcinogenesis ZA7806950B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US05/929,094 US4323581A (en) 1978-07-31 1978-07-31 Method of treating carcinogenesis

Publications (1)

Publication Number Publication Date
ZA7806950B true ZA7806950B (en) 1980-08-27

Family

ID=25457315

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA786950A ZA7806950B (en) 1978-07-31 1978-12-12 Method of preventing carcinogenesis

Country Status (3)

Country Link
US (1) US4323581A (en)
CA (1) CA1142092A (en)
ZA (1) ZA7806950B (en)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4665098A (en) * 1985-03-28 1987-05-12 Mcneilab, Inc. Pharmaceutical composition of N-(4-hydroxyphenyl) retinamide having increased bioavailability
US4743400A (en) * 1986-09-22 1988-05-10 Mcneilab, Inc. Process for preparing retinoyl chlorides
CA1320161C (en) * 1987-12-16 1993-07-13 Hugues Blaudin De The Steroid/thyroid hormone receptor-related gene, which is inappropriately expressed in human heptocellular carcinoma, and which is a retinoic acid receptor
US5399757A (en) * 1993-07-20 1995-03-21 Ortho Pharmaceutical Corporation Process for the preparation of N-(4-hydroxyphenyl)-retinamide
US5703130A (en) * 1995-06-07 1997-12-30 Institute Of Materia Medica, An Institute Of The Chinese Academy Of Medical Sciences Chalcone retinoids and methods of use of same
US5716982A (en) * 1995-06-07 1998-02-10 Institute Of Materia Medica, An Institute Of The Chinese Academy Of Medical Sciences Retinoids and methods of use of same
US5968940A (en) * 1995-06-08 1999-10-19 Institute Of Materia Medica Retinoids and methods of use of same
US6368831B1 (en) 1998-06-29 2002-04-09 Childrens Hospital Los Angeles Treatment of hyperproliferative disorders
AT409486T (en) 1998-06-29 2008-10-15 Children S Hospital Los Angele Treatment of hyperproliferative diseases
EP2266590A3 (en) 2002-02-22 2011-04-20 Shire LLC Active agent delivery sytems and methods for protecting and administering active agents
AT414511T (en) 2000-12-05 2008-12-15 Los Angeles Childrens Hospital Pharmaceutical compositions of fenretinide with increased bioavailability and method for their use
WO2005072091A2 (en) * 2003-12-09 2005-08-11 The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services Methods for inhibiting hiv and other viral infections by modulating ceramide metabolism
GEP20084520B (en) 2004-06-23 2008-10-27 Sirion Therapeutics Inc Use of retinyl derivatives and compositions thereof for treating ophthalmic diseases
CA2571421A1 (en) 2004-06-24 2006-01-05 Nicholas Valiante Compounds for immunopotentiation
EP1804788A4 (en) * 2004-10-25 2008-05-21 Sirion Therapeutics Inc Detection and analysis of ophthalmically-relevant fluorescent molecules
KR20070091283A (en) * 2004-11-04 2007-09-10 시리온 테라퓨틱스, 인크. Modulators of retinol-retinol binding protein(rbp)-transthyretin(ttr) complex formation
UA81382C2 (en) * 2005-07-11 2007-12-25 Composition for treating retinol-related diseases by modulation of retinol binding
KR20060094745A (en) * 2005-02-25 2006-08-30 (주)나노하이브리드 Phamaceutical composition for the treatment of cancer comprising lmh-ra complex
JO2660B1 (en) 2006-01-20 2012-06-17 نوفارتيس ايه جي PI-3 Kinase inhibitors and methods of their use
PE20070978A1 (en) * 2006-02-14 2007-11-15 Novartis Ag HETEROCYCLIC COMPOUNDS AS INHIBITORS OF PHOSPHATIDYLINOSITOL 3-KINASES (PI3Ks)
EP2013016B8 (en) 2006-03-29 2014-10-08 Wayne State University Liposomal nanoparticles and other formulations of fenretinide for use in therapy and drug delivery
TW200808739A (en) * 2006-04-06 2008-02-16 Novartis Vaccines & Diagnostic Quinazolines for PDK1 inhibition
US7321064B1 (en) * 2007-03-08 2008-01-22 Cedarburg Pharmaceuticals, Inc. Preparation of amides of retinoic acid via mixed anhydride and mixed carbonate intermediates
CN101952282A (en) 2007-12-20 2011-01-19 诺瓦提斯公司 Thiazole derivatives used as PI 3 kinase inhibitors
CN101229147B (en) * 2007-12-24 2010-09-01 复旦大学 Use of N-4-hydroxyphenyl retinamide on preparing anti-hepatic fibrosis medicine
US8293753B2 (en) 2009-07-02 2012-10-23 Novartis Ag Substituted 2-carboxamide cycloamino ureas
AR082418A1 (en) 2010-08-02 2012-12-05 Novartis Ag Crystalline forms of 1- (4-methyl-5- [2- (2,2,2-trifluoro-1,1-dimethyl-ethyl) -pyridin-4-yl] -thiazol-2-yl) -amide of 2 -Pyrrolidine-1,2-dicarboxylic acid (s) amide
AP201307043A0 (en) 2011-01-31 2013-08-31 Novartis Ag Novel heterocyclic derivatives
CA2853256C (en) 2011-10-28 2019-05-14 Novartis Ag Novel purine derivatives and their use in the treatment of disease
CN104349779A (en) 2012-05-16 2015-02-11 诺华股份有限公司 Dosage regimen for a pi-3 kinase inhibitor
CA3002954A1 (en) 2015-11-02 2017-05-11 Novartis Ag Dosage regimen for a phosphatidylinositol 3-kinase inhibitor
WO2018060833A1 (en) 2016-09-27 2018-04-05 Novartis Ag Dosage regimen for alpha-isoform selective phosphatidylinositol 3-kinase inhibitor alpelisib

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4108880A (en) * 1975-11-03 1978-08-22 Johnson & Johnson Esters of retinoic acid

Also Published As

Publication number Publication date
CA1142092A1 (en)
US4323581A (en) 1982-04-06
CA1142092A (en) 1983-03-01

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ZA7806950B (en) Method of preventing carcinogenesis