ZA737653B - Tetrahydro pyrrolo(1,2-a)pyrazine-1(2h),4(3h)-diones - Google Patents

Tetrahydro pyrrolo(1,2-a)pyrazine-1(2h),4(3h)-diones

Info

Publication number
ZA737653B
ZA737653B ZA737653*A ZA737653A ZA737653B ZA 737653 B ZA737653 B ZA 737653B ZA 737653 A ZA737653 A ZA 737653A ZA 737653 B ZA737653 B ZA 737653B
Authority
ZA
South Africa
Prior art keywords
diones
pyrazine
tetrahydro pyrrolo
pyrrolo
tetrahydro
Prior art date
Application number
ZA737653*A
Other languages
English (en)
Inventor
L Fontanella
L Mariani
Original Assignee
Lepetit Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lepetit Spa filed Critical Lepetit Spa
Publication of ZA737653B publication Critical patent/ZA737653B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA737653*A 1972-11-03 1973-09-28 Tetrahydro pyrrolo(1,2-a)pyrazine-1(2h),4(3h)-diones ZA737653B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT3127672 1972-11-03

Publications (1)

Publication Number Publication Date
ZA737653B true ZA737653B (en) 1974-08-28

Family

ID=11233382

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA737653*A ZA737653B (en) 1972-11-03 1973-09-28 Tetrahydro pyrrolo(1,2-a)pyrazine-1(2h),4(3h)-diones

Country Status (18)

Country Link
US (1) US3920660A (fr)
JP (1) JPS4976896A (fr)
AR (1) AR206504A1 (fr)
AT (1) AT336622B (fr)
AU (1) AU475776B2 (fr)
BE (1) BE806827A (fr)
DD (1) DD107930A5 (fr)
DE (1) DE2354056A1 (fr)
ES (2) ES420175A1 (fr)
FR (1) FR2205323B1 (fr)
GB (1) GB1409185A (fr)
HU (1) HU166438B (fr)
IL (2) IL43485A0 (fr)
LU (1) LU68719A1 (fr)
NL (1) NL7314665A (fr)
RO (1) RO63259A (fr)
SU (1) SU513627A3 (fr)
ZA (1) ZA737653B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4697016A (en) * 1984-10-26 1987-09-29 Ciba-Geigy Corporation Intermediates for the preparation of a carboxylic acid
US4595766A (en) * 1984-10-26 1986-06-17 Ciba-Geigy Corporation Process for the preparation of an indoline carboxylic acid
JPH0745501B2 (ja) * 1986-11-27 1995-05-17 日本臓器製薬株式会社 新規環状ジペプチド化合物
DE3830096A1 (de) * 1988-09-03 1990-03-15 Hoechst Ag Piperazindione mit psychotroper wirkung
WO1993023404A1 (fr) * 1992-05-19 1993-11-25 Immunopharmaceutics, Inc. Composes modulant l'activite de l'endotheline
US6057314A (en) * 1995-12-21 2000-05-02 Biochem Pharma Inc. Low molecular weight bicyclic thrombin inhibitors
US5958905A (en) 1996-03-26 1999-09-28 Texas Biotechnology Corporation Phosphoramidates, phosphinic amides and related compounds and the use thereof to modulate the activity of endothelin
AU3232597A (en) * 1996-06-18 1998-01-07 Warner-Lambert Company Pyrrolo{1,2-a}pyrazine-1,4-dione serine protease inhibitors
WO2001046195A1 (fr) 1999-12-21 2001-06-28 Gpi Nil Holdings, Inc. Composes a base de derives d'hydantoïne, compositions pharmaceutiques, et modes d'utilisation
WO2002062797A2 (fr) * 2000-12-29 2002-08-15 Celltech R & D, Inc. Utilisations pharmaceutiques et synthese de dicetopiperazines
CA2900335C (fr) * 2012-10-22 2021-10-26 City Of Hope Analogues synthetiques d'epipolythiodioxopiperazines et leurs utilisations
CA3036852A1 (fr) 2016-09-15 2018-03-22 City Of Hope Derives dithio etp

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3176017A (en) * 1963-02-26 1965-03-30 American Home Prod Aroylalkyl derivatives of diazabicyclo-nonanes and-decanes
US3503980A (en) * 1965-10-04 1970-03-31 Ciba Geigy Corp Tetrahydroazacycloalkano(1,2-a) pyridazines
DE1695554C3 (de) * 1966-02-12 1974-02-21 Nautschno-Issledowatelskij Institut Farmakologii I Chimioterapii, Moskau Verfahren zur Herstellung kondensierter Piperazinonderivate
US3563992A (en) * 1967-10-31 1971-02-16 Abbott Lab 1,4-diaza-bicyclo(4,3,0)nonane-2,5,9-triones

Also Published As

Publication number Publication date
FR2205323A1 (fr) 1974-05-31
AU475776B2 (en) 1976-09-02
NL7314665A (fr) 1974-05-07
JPS4976896A (fr) 1974-07-24
IL43485A0 (en) 1974-01-14
SU513627A3 (ru) 1976-05-05
GB1409185A (en) 1975-10-08
US3920660A (en) 1975-11-18
AU6141773A (en) 1975-04-17
DE2354056A1 (de) 1974-05-16
ES421819A1 (es) 1976-06-16
BE806827A (fr) 1974-02-15
FR2205323B1 (fr) 1976-12-03
IL43606A0 (en) 1974-03-14
RO63259A (fr) 1978-08-15
AT336622B (de) 1977-05-10
LU68719A1 (fr) 1974-01-08
AR206504A1 (es) 1976-07-30
ES420175A1 (es) 1976-07-16
HU166438B (fr) 1975-03-28
ATA925273A (de) 1976-09-15
DD107930A5 (fr) 1974-08-20

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