ZA200905996B - Process for preparing isomers of carmoterol - Google Patents
Process for preparing isomers of carmoterolInfo
- Publication number
- ZA200905996B ZA200905996B ZA200905996A ZA200905996A ZA200905996B ZA 200905996 B ZA200905996 B ZA 200905996B ZA 200905996 A ZA200905996 A ZA 200905996A ZA 200905996 A ZA200905996 A ZA 200905996A ZA 200905996 B ZA200905996 B ZA 200905996B
- Authority
- ZA
- South Africa
- Prior art keywords
- carmoterol
- preparing isomers
- isomers
- preparing
- Prior art date
Links
- IHOXNOQMRZISPV-YJYMSZOUSA-N 5-[(1r)-1-hydroxy-2-[[(2r)-1-(4-methoxyphenyl)propan-2-yl]azaniumyl]ethyl]-2-oxo-1h-quinolin-8-olate Chemical class C1=CC(OC)=CC=C1C[C@@H](C)NC[C@H](O)C1=CC=C(O)C2=C1C=CC(=O)N2 IHOXNOQMRZISPV-YJYMSZOUSA-N 0.000 title 1
- 229950010713 carmoterol Drugs 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN391MU2007 | 2007-02-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200905996B true ZA200905996B (en) | 2010-05-26 |
Family
ID=39366461
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200905996A ZA200905996B (en) | 2007-02-28 | 2009-08-27 | Process for preparing isomers of carmoterol |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8236959B2 (xx) |
| EP (1) | EP2132179B1 (xx) |
| JP (1) | JP2010520188A (xx) |
| KR (1) | KR20090121360A (xx) |
| AU (1) | AU2008220617B2 (xx) |
| CA (1) | CA2679059A1 (xx) |
| NZ (1) | NZ579244A (xx) |
| WO (1) | WO2008104781A1 (xx) |
| ZA (1) | ZA200905996B (xx) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010520188A (ja) | 2007-02-28 | 2010-06-10 | シプラ・リミテッド | カルモテロールの異性体を調製する方法 |
| EP2116537A1 (en) * | 2008-05-07 | 2009-11-11 | CHIESI FARMACEUTICI S.p.A. | Polymorph of 8-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]-2(1H)-quinolinone monohydrochloride |
| BR112013030302B1 (pt) | 2011-06-10 | 2021-08-24 | Chiesi Farmaceutici S.P.A. | Composto, composição farmacêutica, uso de um composto, combinação de um composto e dispositivo |
| US10227305B2 (en) * | 2014-08-22 | 2019-03-12 | G. Pratap REDDY | Process for preparing indacaterol and salts thereof |
| TWI703138B (zh) | 2015-02-12 | 2020-09-01 | 義大利商吉斯藥品公司 | 具有蕈毒鹼受體拮抗劑及β２腎上腺素受體促效劑活性之化合物 |
| CN106334578B (zh) * | 2016-07-29 | 2018-10-23 | 马鞍山市泰博化工科技有限公司 | 一种喹啉衍生物、该衍生物的合成方法及其合成用催化剂 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4579857A (en) * | 1983-02-14 | 1986-04-01 | Schering Corporation | Anti-inflammatory 1-mercaptoalkyl-substituted-2-imidazolidinone derivatives, composition, and method of use therefor |
| GB8334494D0 (en) * | 1983-12-24 | 1984-02-01 | Tanabe Seiyaku Co | Carbostyril derivatives |
| US4894219A (en) * | 1988-03-29 | 1990-01-16 | University Of Florida | Beta-agonist carbostyril derivatives, assay method and pharmacological composition |
| JPH0525045A (ja) * | 1991-07-18 | 1993-02-02 | Tanabe Seiyaku Co Ltd | 経皮吸収製剤 |
| GB9405019D0 (en) | 1994-03-15 | 1994-04-27 | Smithkline Beecham Plc | Novel compounds |
| TWI324150B (en) | 2003-02-28 | 2010-05-01 | Novartis Ag | Process for preparing 5-[(r)-2-(5,6-diethyl-indan-2-ylamino)-1-hydroxy-ethyl]-8-hydroxy-(1h)-quinolin-2-one salt |
| CA2565243A1 (en) * | 2004-05-13 | 2005-11-24 | Boehringer Ingelheim International Gmbh | Hydroxy-substituted benzo-condensed heterocycles for use as beta agonists in the treatment of respiratory diseases |
| US7307076B2 (en) * | 2004-05-13 | 2007-12-11 | Boehringer Ingelheim International Gmbh | Beta agonists for the treatment of respiratory diseases |
| AU2006275137A1 (en) * | 2005-08-01 | 2007-02-08 | Chiesi Farmaceutici S.P.A. | Pharmaceutical formulations comprising a long-acting beta2-agonist for administration by nebulisation |
| JP2010520188A (ja) | 2007-02-28 | 2010-06-10 | シプラ・リミテッド | カルモテロールの異性体を調製する方法 |
-
2008
- 2008-02-28 JP JP2009551265A patent/JP2010520188A/ja active Pending
- 2008-02-28 AU AU2008220617A patent/AU2008220617B2/en not_active Expired - Fee Related
- 2008-02-28 EP EP08709552A patent/EP2132179B1/en not_active Not-in-force
- 2008-02-28 WO PCT/GB2008/000677 patent/WO2008104781A1/en active Application Filing
- 2008-02-28 US US12/528,687 patent/US8236959B2/en not_active Expired - Fee Related
- 2008-02-28 KR KR1020097020022A patent/KR20090121360A/ko not_active Application Discontinuation
- 2008-02-28 CA CA002679059A patent/CA2679059A1/en not_active Abandoned
- 2008-02-28 NZ NZ579244A patent/NZ579244A/en not_active IP Right Cessation
-
2009
- 2009-08-27 ZA ZA200905996A patent/ZA200905996B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20100113790A1 (en) | 2010-05-06 |
| AU2008220617A1 (en) | 2008-09-04 |
| AU2008220617B2 (en) | 2012-12-06 |
| KR20090121360A (ko) | 2009-11-25 |
| EP2132179A1 (en) | 2009-12-16 |
| JP2010520188A (ja) | 2010-06-10 |
| EP2132179B1 (en) | 2012-08-08 |
| NZ579244A (en) | 2012-04-27 |
| WO2008104781A1 (en) | 2008-09-04 |
| CA2679059A1 (en) | 2008-09-04 |
| US8236959B2 (en) | 2012-08-07 |
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