ZA200802163B - 5-(phenylisoxazolylethoxy)-triazol-3-YL substituted pyridine compounds for the treatment of neurological, psychiatric or pain disorders - Google Patents

5-(phenylisoxazolylethoxy)-triazol-3-YL substituted pyridine compounds for the treatment of neurological, psychiatric or pain disorders

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Publication number
ZA200802163B
ZA200802163B ZA200802163A ZA200802163A ZA200802163B ZA 200802163 B ZA200802163 B ZA 200802163B ZA 200802163 A ZA200802163 A ZA 200802163A ZA 200802163 A ZA200802163 A ZA 200802163A ZA 200802163 B ZA200802163 B ZA 200802163B
Authority
ZA
South Africa
Prior art keywords
phenylisoxazolylethoxy
psychiatric
triazol
neurological
treatment
Prior art date
Application number
ZA200802163A
Other languages
English (en)
Inventor
Minidis Alexander
Wensbo David
Slassi Abdelmalik
Isaac Methvin
Ericsson Caroline
Profir Veronica
Bergstrom Per-Olov
Edwards Louise
Arora Jalaj
Xin Tao
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of ZA200802163B publication Critical patent/ZA200802163B/xx

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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  • Engineering & Computer Science (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Psychiatry (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Virology (AREA)
  • Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Addiction (AREA)
  • Hospice & Palliative Care (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Anesthesiology (AREA)
ZA200802163A 2005-09-29 2008-03-07 5-(phenylisoxazolylethoxy)-triazol-3-YL substituted pyridine compounds for the treatment of neurological, psychiatric or pain disorders ZA200802163B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US72152705P 2005-09-29 2005-09-29

Publications (1)

Publication Number Publication Date
ZA200802163B true ZA200802163B (en) 2009-09-30

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ZA200802163A ZA200802163B (en) 2005-09-29 2008-03-07 5-(phenylisoxazolylethoxy)-triazol-3-YL substituted pyridine compounds for the treatment of neurological, psychiatric or pain disorders

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Country Link
US (4) US7476684B2 (ja)
EP (1) EP1934209A1 (ja)
JP (2) JP2009510064A (ja)
KR (1) KR20080050421A (ja)
CN (1) CN101273037A (ja)
AR (1) AR058807A1 (ja)
AU (1) AU2006297462A1 (ja)
BR (1) BRPI0616228A2 (ja)
CA (1) CA2623009A1 (ja)
EC (1) ECSP088283A (ja)
IL (1) IL189990A0 (ja)
NO (1) NO20081434L (ja)
RU (1) RU2008108219A (ja)
TW (1) TW200800976A (ja)
UA (1) UA92503C2 (ja)
UY (1) UY29796A1 (ja)
WO (1) WO2007040982A1 (ja)
ZA (1) ZA200802163B (ja)

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KR20110040910A (ko) * 2008-08-12 2011-04-20 아스트라제네카 아베 4-(5-((1ｒ)-1-[5-(3-클로로페닐)이속사졸-3-일]에톡시)-4-메틸-4ｈ-1,2,4-트리아졸-3-일)피리딘의 결정질 형태
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US20110306768A1 (en) * 2008-12-18 2011-12-15 Astrazeneca Ab Processes for the manufacture of 3--pyridine, 4-methyl-3-methylthio-5-(3-pyridyl)-l,2,4-triazole, and (1r)-1-[2-(3-methylphenyl)-2h-tetrazol-5-yl]ethanol
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WO2011092293A2 (en) 2010-02-01 2011-08-04 Novartis Ag Cyclohexyl amide derivatives as crf receptor antagonists
AR080055A1 (es) 2010-02-01 2012-03-07 Novartis Ag Derivados de pirazolo-[5,1-b]-oxazol como antagonistas de los receptores de crf -1
CN102753527B (zh) 2010-02-02 2014-12-24 诺华股份有限公司 用作crf受体拮抗剂的环己基酰胺衍生物
US8080568B1 (en) * 2010-06-29 2011-12-20 Ewha University - Industry Collaboration Foundation 2-pyridyl substituted imidazoles as therapeutic ALK5 and/or ALK4 inhibitors
UA112418C2 (uk) * 2010-09-07 2016-09-12 Астеллас Фарма Інк. Терапевтичний болезаспокійливий засіб
RU2013128448A (ru) 2010-12-08 2015-01-20 Осло Юниверсити Хоспитал Хф Производные триазола в качестве ингибиторов сигнального пути wnt
US20140228398A1 (en) 2011-03-18 2014-08-14 Novartis Ag COMBINATIONS OF ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR ACTIVATORS AND mGluR5 ANTAGONISTS FOR USE IN DOPAMINE INDUCED DYSKINESIA IN PARKINSON'S DISEASE
KR20160120157A (ko) 2015-04-07 2016-10-17 주식회사 메드팩토 암 예방 또는 치료용 약학적 조성물 및 이를 이용한 방법
WO2016163754A1 (en) * 2015-04-07 2016-10-13 Medpacto Inc. Pharmaceutical composition for preventing or treating cancer and method using thereof
KR102027368B1 (ko) * 2018-05-29 2019-10-01 서울대학교산학협력단 통증의 강도를 측정하는 방법
CN113811297B (zh) * 2019-05-15 2024-03-26 克拉斯·图林 用于预防和/或治疗动物中的疼痛的4-[5-[(rac)-1-[5-(3-氯苯基)-3-异噁唑基]乙氧基]-4-甲基-4H-1,2,4-三唑-3-基]吡啶
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WO2005077368A2 (en) 2004-02-03 2005-08-25 Astrazeneca Ab Treatment of gastro-esophageal reflux disease (gerd)
WO2005077345A1 (en) 2004-02-03 2005-08-25 Astrazeneca Ab Compounds for the treatment of gastro-esophageal reflux disease
US7585881B2 (en) 2004-02-18 2009-09-08 Astrazeneca Ab Additional heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
PL1716152T3 (pl) 2004-02-18 2009-01-30 Astrazeneca Ab Skondensowane związki heterocykliczne i ich zastosowanie jako antagonistów receptora metabotropowego do leczenia zaburzeń żołądkowo-jelitowych
BRPI0507499A (pt) 2004-02-18 2007-07-24 Astrazeneca Ab composto ou um sal farmaceuticamente aceitável ou hidrato dos mesmos, composição farmacêutica, uso do composto, e, métodos para tratar distúrbios mediados por mglur 5 e para inibir a ativação de receptores de mglur 5
SG150539A1 (en) 2004-02-18 2009-03-30 Astrazeneca Ab Tetrazole compounds and their use as metabotropic glutamate receptor antagonists
KR20070052693A (ko) 2004-02-18 2007-05-22 아스트라제네카 아베 폴리헤테로시클릭 화합물 및 대사성 글루타메이트 수용체길항제로서 이들의 용도
CA2554894A1 (en) 2004-02-18 2005-09-01 Astrazeneca Ab Triazole compounds and their use as metabotropic glutamate receptor antagonists
UY29796A1 (es) * 2005-09-29 2007-04-30 Astrazeneca Ab Nuevos compuestos para el tratamiento de trastornos neurológicos, psiquiátricos o del dolor

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KR20080050421A (ko) 2008-06-05
WO2007040982A1 (en) 2007-04-12
JP2009510064A (ja) 2009-03-12
RU2008108219A (ru) 2009-11-10
AR058807A1 (es) 2008-02-27
US20070129408A1 (en) 2007-06-07
ECSP088283A (es) 2008-04-28
CN101273037A (zh) 2008-09-24
AU2006297462A1 (en) 2007-04-12
UA92503C2 (ru) 2010-11-10
US20080227824A1 (en) 2008-09-18
US20070270469A1 (en) 2007-11-22
EP1934209A1 (en) 2008-06-25
IL189990A0 (en) 2008-08-07
BRPI0616228A2 (pt) 2011-06-14
NO20081434L (no) 2008-05-19
UY29796A1 (es) 2007-04-30
TW200800976A (en) 2008-01-01
JP2010013476A (ja) 2010-01-21
US7476684B2 (en) 2009-01-13
CA2623009A1 (en) 2007-04-12
US20070270468A1 (en) 2007-11-22

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