ZA200800930B - Fluoro substituted 2-oxo azepan derivatives - Google Patents

Fluoro substituted 2-oxo azepan derivatives

Info

Publication number
ZA200800930B
ZA200800930B ZA200800930A ZA200800930A ZA200800930B ZA 200800930 B ZA200800930 B ZA 200800930B ZA 200800930 A ZA200800930 A ZA 200800930A ZA 200800930 A ZA200800930 A ZA 200800930A ZA 200800930 B ZA200800930 B ZA 200800930B
Authority
ZA
South Africa
Prior art keywords
fluoro substituted
oxo azepan
azepan derivatives
derivatives
oxo
Prior art date
Application number
ZA200800930A
Other languages
English (en)
Inventor
Flohr Alexander
Jakob-Roetne Roland
Wostl Wolfgang
Gally Guido
Kitas Eric Argirios
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ZA200800930B publication Critical patent/ZA200800930B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/12Nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA200800930A 2005-08-12 2008-01-29 Fluoro substituted 2-oxo azepan derivatives ZA200800930B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05107455 2005-08-12

Publications (1)

Publication Number Publication Date
ZA200800930B true ZA200800930B (en) 2009-02-25

Family

ID=37102441

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200800930A ZA200800930B (en) 2005-08-12 2008-01-29 Fluoro substituted 2-oxo azepan derivatives

Country Status (19)

Country Link
US (1) US7501406B2 (de)
EP (1) EP1915345B1 (de)
JP (1) JP4885958B2 (de)
KR (1) KR101020397B1 (de)
CN (1) CN101238106B (de)
AR (1) AR055370A1 (de)
AT (1) ATE492536T1 (de)
AU (1) AU2006281493A1 (de)
BR (1) BRPI0614566A2 (de)
CA (1) CA2619223A1 (de)
DE (1) DE602006019103D1 (de)
ES (1) ES2355581T3 (de)
IL (1) IL189026A0 (de)
MX (1) MX2008001833A (de)
NO (1) NO20080498L (de)
RU (1) RU2419611C2 (de)
TW (1) TWI325421B (de)
WO (1) WO2007020190A1 (de)
ZA (1) ZA200800930B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010509235A (ja) * 2006-11-03 2010-03-25 ノースウェスタン ユニバーシティ 多発性硬化症の治療
FR2913886B1 (fr) 2007-03-22 2012-03-02 Guerbet Sa Utilisation de nanoparticules metalliques dans le diagnostique de la maladie d'alzheimer
GB201009603D0 (en) 2010-06-08 2010-07-21 Cambridge Entpr Ltd Anti-inflammatory agent
WO2012014127A1 (en) 2010-07-30 2012-02-02 Ranbaxy Laboratories Limited 5-lipoxygenase inhibitors
AR097279A1 (es) 2013-08-09 2016-03-02 Actelion Pharmaceuticals Ltd Derivados de benzimidazolil-metil urea como agonistas del receptor de alx

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004508289A (ja) * 2000-04-03 2004-03-18 デュポン ファーマシューティカルズ カンパニー Aβタンパク質産生の阻害剤としての環状ラクタム
MXPA05010055A (es) * 2003-03-24 2005-11-23 Actimis Pharmaceuticals Inc Derivados de 2-fenoxi- y 2-fenil-sulfomamida con actividad antagonista del ccr3, para el tratamiento del asma y otros desordenes inflamatorios o inmunologicos.
JP2007512242A (ja) * 2003-10-29 2007-05-17 イーラン ファーマスーティカルズ、インコーポレイテッド N−置換ベンゼンスルホンアミド
KR100880972B1 (ko) * 2004-07-13 2009-02-03 에프. 호프만-라 로슈 아게 설폰아마이드 유도체

Also Published As

Publication number Publication date
WO2007020190A1 (en) 2007-02-22
NO20080498L (no) 2008-03-07
JP2009504600A (ja) 2009-02-05
CN101238106B (zh) 2011-02-16
CN101238106A (zh) 2008-08-06
DE602006019103D1 (de) 2011-02-03
ATE492536T1 (de) 2011-01-15
RU2008103452A (ru) 2009-09-20
KR101020397B1 (ko) 2011-03-08
JP4885958B2 (ja) 2012-02-29
TW200734308A (en) 2007-09-16
CA2619223A1 (en) 2007-02-22
EP1915345B1 (de) 2010-12-22
TWI325421B (en) 2010-06-01
RU2419611C2 (ru) 2011-05-27
KR20080027936A (ko) 2008-03-28
IL189026A0 (en) 2008-08-07
US7501406B2 (en) 2009-03-10
AU2006281493A1 (en) 2007-02-22
EP1915345A1 (de) 2008-04-30
AR055370A1 (es) 2007-08-22
BRPI0614566A2 (pt) 2009-08-04
ES2355581T3 (es) 2011-03-29
US20070037789A1 (en) 2007-02-15
MX2008001833A (es) 2008-04-09

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