ZA200700168B - Remodeling and glycoconjugation of peptides - Google Patents

Remodeling and glycoconjugation of peptides

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Publication number
ZA200700168B
ZA200700168B ZA200700168A ZA200700168A ZA200700168B ZA 200700168 B ZA200700168 B ZA 200700168B ZA 200700168 A ZA200700168 A ZA 200700168A ZA 200700168 A ZA200700168 A ZA 200700168A ZA 200700168 B ZA200700168 B ZA 200700168B
Authority
ZA
South Africa
Prior art keywords
glycoconjugation
remodeling
peptides
Prior art date
Application number
ZA200700168A
Other languages
English (en)
Inventor
Frees Shawn De
David Zopf
Robert Bayer
Caryn Hakes David Bowe
Chen Xi
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of ZA200700168B publication Critical patent/ZA200700168B/xx

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
    • C12N9/2445—Beta-glucosidase (3.2.1.21)
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    • A61K47/549—Sugars, nucleosides, nucleotides or nucleic acids
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