ZA200510025B - Pharmaceutical compositions comprising active vitamin D compounds - Google Patents

Info

Publication number

ZA200510025B

ZA200510025B ZA200510025A ZA200510025A ZA200510025B ZA 200510025 B ZA200510025 B ZA 200510025B ZA 200510025 A ZA200510025 A ZA 200510025A ZA 200510025 A ZA200510025 A ZA 200510025A ZA 200510025 B ZA200510025 B ZA 200510025B

Authority

ZA

South Africa

Prior art keywords

vitamin

pharmaceutical composition

tpgs

miglyol

gelucire

Prior art date

2003-06-11

Links

• Espacenet
• Global Dossier
• Discuss

• -1 vitamin D compounds Chemical class 0.000 title claims description 177
• 229930003316 Vitamin D Natural products 0.000 title claims description 143
• QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 title claims description 143
• 235000019166 vitamin D Nutrition 0.000 title claims description 143
• 239000011710 vitamin D Substances 0.000 title claims description 143
• 229940046008 vitamin d Drugs 0.000 title claims description 143
• 239000008194 pharmaceutical composition Substances 0.000 title claims description 75
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• 235000020964 calcitriol Nutrition 0.000 claims description 176
• GMRQFYUYWCNGIN-NKMMMXOESA-N calcitriol Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@@H](CCCC(C)(C)O)C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C GMRQFYUYWCNGIN-NKMMMXOESA-N 0.000 claims description 155
• 229960005084 calcitriol Drugs 0.000 claims description 155
• AOBORMOPSGHCAX-UHFFFAOYSA-N Tocophersolan Chemical compound OCCOC(=O)CCC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C AOBORMOPSGHCAX-UHFFFAOYSA-N 0.000 claims description 71
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• 239000004322 Butylated hydroxytoluene Substances 0.000 claims description 15
• NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 claims description 15
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