ZA200300833B - Dipeptidyl peptidase IV inhibitors and their uses as anti-cancer agents. - Google Patents

Dipeptidyl peptidase IV inhibitors and their uses as anti-cancer agents.

Info

Publication number
ZA200300833B
ZA200300833B ZA200300833A ZA200300833A ZA200300833B ZA 200300833 B ZA200300833 B ZA 200300833B ZA 200300833 A ZA200300833 A ZA 200300833A ZA 200300833 A ZA200300833 A ZA 200300833A ZA 200300833 B ZA200300833 B ZA 200300833B
Authority
ZA
South Africa
Prior art keywords
anti
uses
cancer agents
dipeptidyl peptidase
iv inhibitors
Prior art date
Application number
ZA200300833A
Inventor
Hans-Ulrich Demuth
Torsten Hoffmann
Stephan Von Hoersten
Original Assignee
Probiodrug Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to EP01114796 priority Critical
Application filed by Probiodrug Ag filed Critical Probiodrug Ag
Publication of ZA200300833B publication Critical patent/ZA200300833B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06Tripeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07Tetrapeptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0804Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0804Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0804Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/081Tripeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0812Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
ZA200300833A 2001-06-27 2002-06-27 Dipeptidyl peptidase IV inhibitors and their uses as anti-cancer agents. ZA200300833B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP01114796 2001-06-27

Publications (1)

Publication Number Publication Date
ZA200300833B true ZA200300833B (en) 2004-02-10

Family

ID=8177756

Family Applications (3)

Application Number Title Priority Date Filing Date
ZA200300833A ZA200300833B (en) 2001-06-27 2002-06-27 Dipeptidyl peptidase IV inhibitors and their uses as anti-cancer agents.
ZA200301312A ZA200301312B (en) 2001-06-27 2002-06-27 Peptide structures useful for competitive modulation of dipertidyl peptidase IV catalysis.
ZA200300595A ZA200300595B (en) 2001-06-27 2003-01-22 Use of dipeptidyl peptidase IV inhibitors.

Family Applications After (2)

Application Number Title Priority Date Filing Date
ZA200301312A ZA200301312B (en) 2001-06-27 2002-06-27 Peptide structures useful for competitive modulation of dipertidyl peptidase IV catalysis.
ZA200300595A ZA200300595B (en) 2001-06-27 2003-01-22 Use of dipeptidyl peptidase IV inhibitors.

Country Status (8)

Country Link
EP (1) EP1399469A2 (en)
JP (1) JP2004530729A (en)
CN (2) CN1688599A (en)
CA (1) CA2419888A1 (en)
NO (1) NO20030900L (en)
RU (2) RU2003105463A (en)
WO (1) WO2003002593A2 (en)
ZA (3) ZA200300833B (en)

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Also Published As

Publication number Publication date
WO2003002593A3 (en) 2003-09-04
NO20030900D0 (en) 2003-02-26
JP2004530729A (en) 2004-10-07
WO2003002593A2 (en) 2003-01-09
RU2003105463A (en) 2004-11-27
ZA200301312B (en) 2004-03-30
CN1471538A (en) 2004-01-28
NO20030900L (en) 2003-04-24
ZA200300595B (en) 2004-02-13
EP1399469A2 (en) 2004-03-24
CA2419888A1 (en) 2003-01-09
RU2299066C2 (en) 2007-05-20
CN1688599A (en) 2005-10-26

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