WO2026006807A1

WO2026006807A1 - Probe mount collar and related methods

Info

Publication number: WO2026006807A1
Application number: PCT/US2025/035800
Authority: WO
Inventors: Stephen Edward SADDOW; Timothy David MILLER; Mark Weston
Original assignee: Biologic Input Output Systems Inc; University of South Florida; University of South Florida St Petersburg
Current assignee: Biologic Input Output Systems Inc; University of South Florida; University of South Florida St Petersburg
Priority date: 2024-06-27
Filing date: 2025-06-27
Publication date: 2026-01-02
Anticipated expiration: 2026-12-27

Abstract

Embodiments of the disclosure provide a system. The system can include a collar configured to at least partially wrap around a nerve. The collar can include a first portion and a second portion pivotally coupled to the first portion. The collar can be configured to pivot between an open configuration and a closed configuration. In the closed configuration, the second portion couples to the first portion to secure the nerve within the collar.

Description

PROBE MOUNT COLLAR AND RELATED METHODS RELATED APPLICATIONS [0001] This application claims the benefit of U.S. Provisional Application Serial Number 63/665,173 entitled “Probe Mount Collar and Related Methods”, filed June 27, 2024, which is incorporated herein by reference in its entirety. TECHNICAL FIELD [0002] The present disclosure generally relates to medical devices and more specifically to implant devices. BACKGROUND [0003] Implantable neural interfaces (INIs) are devices configured to connect with the human nervous system through electrical means. Advantageously, such devices allow electrical recording and stimulation of the nervous system and may contribute to developing effective treatments for various nervous system diseases (e.g., chronic pain, arrythmia, Parkinson’s, Alzheimer’s, and poliomyelitis). [0004] However, the materials used for conventional INIs (e.g., silicon and noble metals) suffer from many limitations. For example, due to a relatively low impedance and small detection window, noble metals and silicon-based INIs have limited application during neural stimulation. Additionally, long-term implantable performance with such devices is poor due to the foreign body response, loss of target neurons, and scar formation (i.e., gliosis). In some instances, a base material, such as Si, has been known to make contact with the neural environment and trigger the body’s immune system response. In some instances this has led to undesirable device encapsulation with glial scar tissue resulting, reducing device performance and patient discomfort. [0005] With rapid improvements in bionic limbs (prosthetic hands, arms, legs, etc.) new challenges arise in the efficient and transparent operation of these advanced devices. Electromyography (EMG) sensors may be used to detect and measure electrical signals in a patient’s muscle, however, this does not allow for specific neural interfacing. Performance using these sensors is limited due to the large number of neural signals that are picked up simultaneously at a single recording electrode, sometimes all at the same time. In addition, this type of interface does not lend itself to accurate and effective neural stimulation, for instance to individual nerves, thus bionic limb feedback signals cannot be fed back to the user. HB: 4903-0572-8081.1 1 [0006] A solution is desired that allows for an increase in the number of individual neural recording/stimulation points that are available, along with reliable, long-term electrode implantation in the peripheral nervous system (PNS). Such a device would preferably improve the number of bionic limb degrees of freedom possible, and also both reduce latency and improve accuracy as contemporary interfaces require a software algorithm and lengthy training to assess and estimate the patient’s intent. While technological advances have been made for interfacing with the central nervous system (CNS) (i.e., brain and spinal cord), neural recording and stimulation of the PNS is more challenging as nerves of the PNS often stretch, compress, twist, change cross-sectional area, etc. as a patient moves. Thus, unique solutions suitable for the PNS are required. [0007] Solutions are also desired that increase the stability and reliability of the connection between an electrode and the nerve or nerve bundle. The devices of the present disclosure provide for improved and secure placement of electrodes and connections to the nerve or nerve bundle, in some cases allowing for longer term deployment and reduced instances of failure and patient discomfort. SUMMARY [0008] Other objects, advantages and novel features of the present invention will become apparent from the following detailed description of the invention when considered in conjunction with the accompanying drawings. [0009] Embodiments of the disclosure provide a system. The system comprises a collar configured to at least partially wrap around a nerve. The collar comprises a first portion and a second portion pivotally coupled to the first portion. The collar is configured to pivot between an open configuration and a closed configuration. In the closed configuration, the second portion couples to the first portion to secure the nerve within the collar. [0010] In one embodiment, a system comprises a fastener configured to couple a first portion and a second portion together. [0011] In one embodiment, a fastener is adjustable, such that a width of a bore defined by a collar is also adjustable. A first portion and a second portion define the bore of the collar. [0012] In one embodiment, a fastener comprises a tooth coupled to a first portion of a collar and a hook coupled to a second portion of the collar. A hook engages with the tooth to lock the collar in a closed configuration. [0013] In one embodiment, a tooth can be a first tooth. A fastener comprises a second tooth disposed above the first tooth. When a hook engages the first tooth to lock the collar in the closed configuration, a bore has a first width. When the hook engages the second tooth to lock the collar in the closed configuration, the bore has a second width, the second width being smaller than the first width. [0014] In one embodiment, a first portion is configured to pivot about a longitudinal axis of a collar. The first portion is configured to pivot about the longitudinal axis of the collar. The longitudinal axis of the collar is substantially parallel to a nerve. [0015] In one embodiment, a system comprises a hinge that is coupled to a first portion and a second portion of the collar. The hinge extends along a longitudinal axis of the collar. [0016] In one embodiment, in a closed configuration, a first portion and a second portion of a collar surround an entire circumference of a nerve. In one embodiment, the nerve is a peripheral nerve. [0017] In one embodiment, a first portion can have a u-shape. A second portion can have a u-shape. A portion of the second portion of the collar wraps around the first portion of a collar when the collar is in a closed configuration. [0018] In one embodiment, in an open configuration, a gap is positioned between a first end of a first portion of a collar and a second end of a second portion of the collar. The gap permits entry of a nerve into a bore of the collar when the collar is in the open configuration. [0019] In one embodiment, in a closed configuration, a collar is secured around a nerve, such that the collar is prevented from translating along a length of the nerve. [0020] In one embodiment, a collar comprises an extension. The extension is coupled to and positioned on top of a first portion of the collar. The extension can segment the first portion of the collar into a first section on one side of the extension and a second section on the opposing side of the extension. [0021] In one embodiment, an extension of a collar comprises a slot configured to receive a probe and a hole at a bottom of the slot. When the probe is positioned within the slot, one or more shanks of the probe pass through the hole and electrically couple to a nerve. [0022] In one embodiment, a slot has a width that is adapted to receive a probe housing that secures a probe therein. [0023] In one embodiment, the probe is attached to a two-piece cable consisting of a first piece cable(A) and a second piece (cable B). [0024] In one embodiment, cable A comprises a percutaneous sensor wire. In one embodiment, the percutaneous sensor wire comprises a multi-strand sensor wire encased in silicone and a silicone housing with an electrical connector, creating a percutaneous sensor cable. [0025] In one embodiment, cable B comprises an electrode implant. In one embodiment, the electrode implant comprises an electrical connector attached to an electrode by a polyamide cable. In one embodiment, cable B is encased in a silicone housing. [0026] In one embodiment, the electrical connector of the percutaneous sensor cable couples with the electrical connector of cable B. The sensor cable passes through the skin to be later connected to a surgical device. [0027] In one embodiment, the length of cable A is dependent on the distance between the nerve and the skin. In one embodiment, cable A is 2-100 centimeters long. In one embodiment, the length of cable A is selected from the group consisting of 3-35, 5-80, 8-75, 10-50, 15-40, 30-40 and 5-25 centimeters long. [0028] In one embodiment, cable B comprises an electrode implant that is seamlessly encased in silicone comprising a polyamide cable bonded to an electrode at the one end, and bonded to a connector at the opposite end, creating an electrode implant connector. The electrode implant connector couples with the percutaneous sensor cable via the electrical connector. When coupled, the entire assembly of cable A and cable B is impervious. [0029] In one embodiment, cable B is 2-10 centimeters long. In one embodiment, the length of cable B is selected from the group consisting of 2 to 9, 3-8, 4-7, 5-6, 2-2.5, 2.5-3, 3- 3.5, 3.5-4, 4-4.5, 4.5-5, 5-5.5 and 5.5-6 centimeters. In one embodiment, the cable is 2-6 centimeters long. [0030] In one embodiment, cable B is 50-150 microns thick. In one embodiment, cable B is 100 microns thick. In one embodiment, the thickness of cable B is selected from the group consisting of 50-100 microns, 100-150 microns, 50-60 microns, 60-70 microns, 70-80 microns, 80-90 microns, 90-100 microns, 100-110 microns, 110-120 microns, 120-130 microns, 130- 140 microns and 140-150 microns. [0031] In one embodiment cable B is a flat, ribbon-style cable 50-150 microns in thickness, where the thickness depends on the number of recording electrodes. Each wire is individually insulated with silicone or polyamide resulting in a thickness of n-electrodes times 50-150 microns per electrode. For example, if each insulated wire is 100 microns thick, the thickness of the ribbon cable would be 100 microns times n wires. A 32 electrode probe, resulting in 32 individually insulated cables, would result in a flat ribbon-style cable of 32 times 100 microns, or 3,200 microns or 3.2 mm thick. [0032] In one embodiment, the individually insulated wires are configured into a circular cross section resulting in a bundle of wires. The diameter of the bundle depends on the number of wires and the diameter of each individually insulated wire. The cylindrical cable resulting from this configuration is less than 3 mm in diameter. In one embodiment, the diameter of the cylindrical cable is 1-3, 1.5-2.5 and 2-3 millimeters in diameter. [0033] In one embodiment, the collar is 0.5 to 10 millimeters thick. In one embodiment, the thickness of the collar is selected from the group consisting of 1-10, 2-9, 3-7, 4-6, 5-8, 2-2- 8, 0.5-1, 1-1.5, 1.5-2, 2-2.5, 2.5-3, 3-3.5, 3.5-4, 4-4.5, 4.5-5, 5-5.5, 5.5-6, 6-6.5, 6.5-7, 7-7.5, 7.5-8, 8-8.5, 8.5-9, 9-9.5. and 9.5-10 millimeters. [0034] In one embodiment, the width and thickness of the collar are varied so as not to interfere with the function of the nerve and collar hinge. [0035] In one embodiment, the width of the collar varies with the diameter of the nerve. In one embodiment, for a cylindrical geometry, there will be width (which is the dimension along the cylinder axis), thickness of the collar (which is the cross-sectional thickness of the collar) and radius, wherein the inside diameter of the collar when fixed to the nerve = outside diameter of the nerve bundle. The outside diameter of the collar = inside diameter + 2 times the collar thickness. In one embodiment, a 500 um thick collar wrapped around a 4 mm diameter nerve would have an outside diameter of 4 mm + 2*0.5 mm or 5 mm. [0036] In one embodiment, the collar can be different diameters depending on the diameter of the nerve. [0037] In one embodiment, the nerve is a child’s nerve, an adult’s nerve, a vagus nerve, a leg nerve, an arm nerve, a kidney nerve or any other nerve located in the body of a mammal. [0038] In one embodiment, the average diameter of a nerve in a mammal varies by the age of the mammal and the type of nerve. For example, the median nerve at the wrist can range from around 3 mm in young children to over 6 mm in older children and young adults. Similarly, the ulnar nerve at the wrist can range from about 2.4 mm to over 5 mm across different age groups. [0039] In one embodiment, the probe housing has a protrusion that comprises one or more fasteners that engages with one or more opposing fasteners of a cable boot of a cable. In one embodiment, engagement between respective fasteners of the protrusion and the cable boot couple the cable boot to a collar. [0040] In one embodiment, one or more fasteners of a protrusion comprises a first extension fastener and a second extension fastener. A protrusion can extend past opposing sides of the extension to define a first seat and a second seat. A cable boot comprises a first arm on one side of the cable boot and a second arm on the opposite side of the cable boot. The cable boot comprises a first arm fastener on the first arm and a second arm fastener on the second arm. When the cable boot of the cable engages with the protrusion, the first arm of the cable boot can engage with the first seat of the extension and the second arm of the cable boot engages with the second seat of the extension. When the cable boot of the cable engages with the protrusion, the first arm fastener can engage with the first extension fastener and the second arm fastener can engage with the second extension fastener to couple the cable boot to the extension. [0041] In one embodiment, a cable boot of a cable is configured to be coupled to a body of the collar. In a closed configuration with the cable boot of the cable coupled to the body of the collar, a width of the cable boot is greater than a width of a portion of the collar and a second portion of the collar. In one embodiment, the cable boot is wider than the cable. [0042] Embodiments of the disclosure provide a system. In one embodiment, the system comprises a collar configured to at least partially wrap around a nerve. In one embodiment, the collar comprises a first portion and a second portion pivotally coupled to the first portion. In one embodiment, the collar is configured to pivot between an open configuration and a closed configuration. In one embodiment, in the closed configuration, the second portion can couple to the first portion to secure the nerve within the collar. In one embodiment, the collar comprises a slot and a hole fluidly coupled to the slot; the system comprises a probe comprising at least one shank. In one embodiment, the system comprises a probe housing surrounding the probe. In one embodiment, the probe housing is insertable into the probe housing, such that the at least one shank is inserted through the hole and engages with the nerve of a subject thereby electrically coupling the nerve to the at least one shank. In one embodiment, the system comprises a cable comprising a cable boot coupled to an end of the cable. In one embodiment, the cable boot is configured to be coupled to the collar with the probe housing, comprising the probe therein, positioned within the slot of the collar. In one embodiment, when the cable boot is coupled to the collar, the cable boot can constrain movement of the probe housing relative to the collar. [0043] In one embodiment, a probe housing comprises a protrusion. In one embodiment, a collar comprises a recess. In one embodiment, when the probe housing is inserted into a slot of the collar, the protrusion of the probe housing inserts into the recess of the collar to prevent translation of the probe housing relative to the collar. [0044] Embodiments of the disclosure provide a method. In one embodiment, the method comprises wrapping a collar around a peripheral nerve of a subject, inserting a probe housing with a probe therein into a body of the collar while the peripheral nerve is positioned within the bore of the collar, inserting one or more shanks of the probe through the collar until the one or more shanks engage with and electrically couple to the peripheral nerve of the subject, coupling a cable boot of a cable to collar while the probe housing with the probe therein is positioned within the collar; and at least one of sensing, using the one or more shanks, an electrical signal from the peripheral nerve, the electrical signal being transmitted through the cable or transmitting, using the cable, an electrical signal to the one or more shanks to stimulate the peripheral nerve. [0045] In one embodiment, wrapping a collar around a peripheral nerve of a subject comprises opening the collar by pivoting a first portion and a second portion of a collar about a hinge of the collar, placing the peripheral nerve into the collar, while the collar is open, and coupling the collar to itself with the peripheral nerve positioned within a bore of the collar. [0046] Embodiments of the disclosure provide a neural collar system. In one embodiment, the system comprises a collar neck having one or more first fasteners and a collar configured to receive one or more nerves. In one embodiment, the collar is configured to a first portion of the collar neck. In one embodiment, the collar comprises one or more flexible fingers each having a second fastener dimensioned to engage the one or more first fasteners. In one embodiment, the collar is configured to circumferentially wrap around the one or more nerves and removably connect the second fastener with the first fastener and hold the collar around the one or more nerves. [0047] In one embodiment, a collar neck comprises a slot defined by an interior surface. In one embodiment, the slot is configured to receive an electrode housing having one or more electrodes configured to contact one or more nerves and transmit electrical signals. [0048] In one embodiment, a collar is spaced from a second portion of the collar neck to create a gap configured to receive one or more fingers and allow the one or more fingers to wrap over a proximal portion of the collar. [0049] In one embodiment, a first fastener comprises a first set of grip teeth and a second fastener comprises a second set of grip teeth dimensioned to engage with the first set of grip teeth. [0050] In one embodiment, a collar neck comprises one or more locking feet that can retain a first fastener. In one embodiment, the locking feet each have a back side facing an inner portion of a slot. In one embodiment, each of the locking feet have a front side opposite the back side. In one embodiment, the front side is lined with teeth. In one embodiment, the locking feet are configured to be pushed away from a slot as the electrode housing presses against a back side of the one or more locking feet and the electrode housing is received by the slot to removably connect with a second fastener. [0051] In one embodiment, one or more locking feet are flexible and are biased toward a slot when an electrode housing is not inside the slot. [0052] In one embodiment, a collar comprises one or more holes that are configured to receive one or more electrodes, allowing the electrodes to extend through a proximal end of the collar. [0053] In one embodiment, a collar comprises an electrode tip slot defined by an interior surface dimensioned to receive one or more distal ends of one or more electrodes. [0054] In one embodiment, a collar neck comprises one or more grip hook recesses defined by an interior surface and configured to receive a surgical instrument. [0055] In one embodiment, a system comprises a cable boot coupled to a data cable. A collar neck comprises a fitting to engage the cable boot. The fitting can create a seal between the cable boot and the collar neck. [0056] In one embodiment, one or more fingers comprise two fingers separated by a space dimensioned to extend alongside at least part of a first portion of a collar neck. [0057] In one embodiment, each of two fingers can have an inner surface adjacent to a space. In one embodiment, at least one of the surfaces is lined with grip teeth forming a second fastener. [0058] Embodiments of the disclosure provide a neural collar system. In one embodiment, the neural collar system is switchable between an open configuration and an engaged configuration. In one embodiment, the system comprises a flexible collar having one or more flexible fingers. In one embodiment, the flexible fingers are open and are configured to hook one or more nerves in the open configuration. In one embodiment, the collar is configured to at least partially wrap around a circumference of the one or more nerves in the engaged configuration. [0059] In one embodiment, a collar is configured to fully wrap around a circumference of one or more nerves in an engaged configuration. [0060] In one embodiment, a system comprises a collar neck having a slot configured to receive an electrode housing. Inserting the electrode housing into the slot can temporarily lock the system in an engaged configuration. [0061] In one embodiment, a collar neck comprises a first fastener and fingers comprising a second fastener configured to engage with the first fastener. [0062] In one embodiment, a first fastener comprises a first set of grip teeth and a second fastener comprises a second set of grip teeth configured to engage with the first set of grip teeth to lock a system in an engaged configuration. [0063] Embodiments of the disclosure provide a method. In one embodiment, the method is for deploying a neural collar system. In one embodiment, the method comprises the steps of (a) hooking one or more nerves with one or more fingers of a collar system, where the collar system comprises a collar neck, a collar comprising the one or more fingers, and a slot configured to receive an electrode housing. In one embodiment, the method further comprises (b) moving the collar into a second position in which the one or more nerves are at least partially surrounded by the collar in a circumferential direction. In one embodiment, the method further comprises (c) wrapping the collar around the one or more nerves, and (d) sliding the electrode housing into the slot. In one embodiment, step (d) can thereby lock the collar into place. [0064] In one embodiment, a collar can loop around an entire circumference of a nerve. [0065] In one embodiment, a collar neck and collar comprise complimentary grip teeth configured to engage the collar with the collar neck. Sliding an electrode housing into a slot can force the grip teeth of the collar neck to couple with the grip teeth of the collar to lock the collar into place. BRIEF DESCRIPTION OF THE DRAWINGS [0066] Features of the present invention will become apparent to those skilled in the art from the following description with reference to the figures, in which: [0067] FIG. 1 is a view of certain features of a collar system according to certain embodiments. [0068] FIG. 2 is a perspective cut-away view of certain features of a collar system according to certain embodiments. [0069] FIG. 3 is a lateral cut-away view of certain features of a collar system and related devices according to certain embodiments. [0070] FIG. 4 is a lateral view of certain features of a collar system and related devices according to certain embodiments. [0071] FIG. 5 is a lateral view similar to that of FIG. 4, showing the engagement of the collar to a patient’s nerve according to certain embodiments. [0072] FIG. 6 is a lateral view similar to that of FIGs. 4, 5, and 6, further showing the collar being wrapped around the patient’s nerve according to certain embodiments. [0073] FIG. 7 is a lateral view similar to that of FIGs.4, 5, 6, and 7, further showing the installation of an electrode into the patient’s nerve according to certain embodiments. [0074] FIG. 8 is a lateral view similar to that of FIGs.4, 5, 6, 7, and 8 further showing the release and detachment of the collar neck from the installation device according to certain embodiments. [0075] FIG. 9 shows an example of a system. [0076] FIG. 10 shows an example of a cross-section of the system of FIG.9 with the collar in a closed configuration around the nerve (e.g., a nerve bundle) and prior to the insertion of the probe into the collar. [0077] FIG. 11 shows an example of a cross-section of the system of FIG.9 with the collar in a closed configuration around the nerve (e.g., a nerve bundle) and with the probe inserted into the collar. [0078] FIG. 12 shows an example of a cross-section of the system of FIG.9 with the collar in a closed configuration around the nerve (e.g., a nerve bundle), with the probe inserted into the collar, and with the cable boot coupled to the collar. [0079] FIG. 13 shows an example of the system of FIG. 9 in the open configuration being deployed by an instrument or tool. [0080] FIG. 14 shows an example of the system of FIG.9 in the closed configuration being deployed by the instrument or tool. [0081] FIG.15 shows a schematic view of the two-piece cable with first piece (CABLE A) and second piece (CABLE B). [0082] FIG. 16 shows a schematic close up view of the polyamide CABLE B and the electrode. [0083] FIG.17 shows a schematic close up view of the electrode implant. [0084] Other objects, advantages and novel features of the present invention will become apparent from the following detailed description of the invention when considered in conjunction with the accompanying drawings. DETAILED DESCRIPTION OF EMBODIMENTS [0085] For simplicity and illustrative purposes, the principles of the present invention are described by referring to various exemplary embodiments thereof. Although the preferred embodiments of the invention are particularly disclosed herein, one of ordinary skill in the art will readily recognize that the same principles are equally applicable to, and can be implemented in other systems, and that any such variation would be within such modifications that do not part from the scope of the present invention. Before explaining the disclosed embodiments of the present invention in detail, it is to be understood that the invention is not limited in its application to the details of any particular arrangement shown, since the invention is capable of other embodiments. The terminology used herein is for the purpose of description and not of limitation. [0086] As used herein and in the claims, the singular forms include the plural reference and vice versa unless the context clearly indicates otherwise. Other than in the operating examples, or where otherwise indicated, all numbers expressing quantities of ingredients or reaction conditions used herein should be understood as modified in all instances by the term “about.” [0087] All patents and other publications identified are expressly incorporated herein by reference for the purpose of describing and disclosing, for example, the methodologies described in such publications that might be used in connection with the present invention. These publications are provided solely for their disclosure prior to the filing date of the present application. Nothing in this regard should be construed as an admission that the inventors are not entitled to antedate such disclosure by virtue of prior invention or for any other reason. All statements as to the date or representation as to the contents of these documents is based on the information available to the applicants and does not constitute any admission as to the correctness of the dates or contents of these documents. [0088] Unless defined otherwise, all technical and scientific terms used herein have the same meaning as those commonly understood to one of ordinary skill in the art to which this invention pertains. Although any known methods, devices, and materials may be used in the practice or testing of the invention, the methods, devices, and materials in this regard are described herein. [0089] In certain embodiments, the “collar” is essentially a strap that wraps around the nerve. The strap holds the electrode in place. In one embodiment, the collar comprises a pliable material. In one embodiment the collar comprises a flexible material. In one embodiment, the collar comprises a material selected from the group consisting of nylon, silicon, biopolymer, and combinations thereof. In one embodiment, the width, thickness, and/or material comprising the collar are varied so as not to interfere with the function of the nerve and collar hinge. [0090] In certain embodiments, the “hook” as used herein is a protruding portion of the end of the surgical tool that functions to grip and hold the probe mount collar. The hook doesn’t have to be a hook. It can be a peg, or just a knurled surface like the pattern you would see on the grasping surface of a pair of forceps. The hooks function as a pair of mandibles, in other words: opposable graspers. [0091] FIG.1 depicts an implantable neural collar system 10 for placement in the body of a patient for receiving and sending electrical signals. The collar system 10 comprises an electrode housing 12, a collar neck 14, and a collar 16. For the purposes of this description, a longitudinal axis 2 extends in the longitudinal direction that travels through the collar, aligned with the nerve axis when a nerve is in place. A vertical axis 4 extends in a proximal/distal direction, where the distal end engages the nerve in use and the proximal end provides access to control the device. The collar neck 14 and electrode housing 12 is considered to be located at the proximal end of the device along vertical axis 4 and the collar 16 is considered to be located at the distal of the device along the vertical axis 4. The axis 6 describes the circumferential direction that loops around the collar 16 or around the circumference of a nerve or nerve bundle, when in use. The radial axis 8 describes any radial axis extending perpendicularly and radially from the longitudinal axis 2. [0092] The electrode housing 12 comprises a probe 20 having one or more electrodes 22 configured to contact one or more nerves to transmit electrical signals while the system is in use. The probe 20 may be fixed inside the electrode housing 12 in such a way to leave electrical contacts exposed on both ends. For example, the probe 20 comprises one or more elongated electrodes 22 each adapted to engage a peripheral nerve. Each electrode 22 has at least one electrically conductive electrode trace, and each electrode trace is configured to electrically couple a respective electrode contact disposed on the surface of the respective elongated electrode 22. Each electrode contact may be arranged to electrically couple with the nerve and may simply be the exposed end of the electrode trace or may be an electrically conductive contact member affixed to the electrode trace and outer surface of the electrode 22. The electrode contact may transmit electrical signals to and/or from the nerves in use. In addition to the electrode contact, each electrode trace may also have an electrical bonding pad 24 for putting the electrode trace in electrical contact with a data cable 32 and/or cable bundle. Preferably, the at least one elongated electrode 22 is formed from silicon carbide and comprises a SiC coating configured as an insulator. In certain embodiments, both the electrode 22 and the base of the probe 20 are formed from silicon carbide and comprises a SiC coating configured as an insulator. [0093] The collar neck 14 comprises a collar package 30 sized to receive the electrode housing 12. For example, the collar package 30 comprises an opening, or slot 36, in the proximal end through which the electrode housing 12 can slide down into place, for example along axis 4. The slot 36 is defined by an interior surface 38 and may have an oval or square cross sectional shape with or without or curved or right angled corners. The slot 36 within the collar package 30 may be sized to provide a close, snug, or secure fit around the electrode housing 12 to keep it in place and the interior surface may be vertical or tapered with the opposite sides of the vertical surface coming together. The collar package 30 also comprises features to hold the electrode housing 12 in place, such as a snap fit with projections, tabs, ridges, or fittings that hold a distal edge surface of the electrode housing 12. The slot 36 may also provide a tight or friction fit, optionally comprising projections, tabs, ridges, or fittings, such that the electrode housing 12 is prevented from sliding out of the collar package 30 once in place. [0094] As will be described in further detail, when the collar system 10 is in place, the electrodes 22 of the probe 20 are embedded into the target nerve as the electrode housing 12 is placed into the collar package 30. The collar package 30 further comprises a fitting that is configured to engage a cable boot 34 coupled to a data cable 32. The cable boot 34, which can snap into the collar neck 16 to provide secure contact between the probe 20 (e.g., the bonding pads 24) and a data cable 32, which can send and/or receive signals to and/or from the probe 20. The fitting may create a seal between the cable boot 34 and the collar package 30 to protect the electrical connections from the environment. The collar neck 14 further comprises collar grip feet and one or more grip hook recesses, which will be described in further detail below. [0095] The collar neck 14 may be fixed to or detachably coupled to a collar 16 that is configured to receive a nerve or nerve bundle in use. The collar 16 may connect to the collar neck 14 at a subset or first portion 44 of the length of the collar neck 14 along axis 2. For example, the collar 16 may connect to the collar neck 14 by connecting to the collar package 30, which may be centered within or otherwise located along the collar neck 14 along longitudinal axis 2. The collar package 30 may extend further along vertical axis 4 towards the distal end of the device (i.e., towards the collar 16) to make contact with the collar 16 while leaving a gap or space 42 between the bottom surface of the collar neck 14 and proximal surface 40 of the proximal end of the collar 16. In this way, the collar 16 may be spaced from a second portion of the collar neck 14 to create the space 42 or gap configured to receive the collar 16. The space 42 may have a thickness or height defined from the distal surface of the collar neck to the proximal surface of the proximal end of the collar. The thickness of the space 42 may be larger than the thickness of the distal end of the collar 16. In use, the space 42 will be able to receive the distal side of the collar 16 when the collar 16 is deployed, during which the distal end of the collar 16 can wrap over the proximal surface of the proximal end of the collar 16. [0096] The collar neck 14 may have a circumferentially rounded distal surface, especially within the first portion 44 of the collar neck 14 where the collar 16 connects to the collar neck 14. This rounded surface can provide a rounded backbone to fit against the collar 16 when the collar 16 is coupled to the collar neck 14. Such rounded shape of the collar neck 14, and thus the distal end of the collar 16, can provide a rounded generally cylindrical space inside the collar 16 that can receive the nerve when in use. This proximal end of the collar 16 can provide a part of the coiled collar 16 that wraps around the nerve when deployed and may wrap to overlap the opposite side of the collar 16. [0097] In general, the collar 16 may be flexible with one or more flexible fingers 50 that extend from the main body of the collar 16. The collar 16 may have a first open configuration, as shown in Figure 1, in which the collar 16 has an open and semi-rounded, hook-like shape. The collar 16 has a second closed configuration, as shown in Figure 3 in which the collar 16 can at least partially wrap around a circumference of one or more nerves. The collar 16 may fully wrap around a circumference of one or more nerves such that parts of the collar 16 overlap as shown in Figure 3. The collar will be in the open configuration when the system is inactive and be moved to or switch to the closed configuration when the system is engaged for use. In the open configuration, the fingers 50 are open configured to be available to hook one or more nerves or nerve bundles. [0098] The body of the collar 16 further comprises an electrode tip slot 52, which may receive the distal tips of the electrodes 22 when the system is in the engaged and active configuration. The electrode tip slot 52 may be defined by an interior surface defining a slot or divot within collar. The electrode tip slot 52 may be dimensioned to receive the distal ends of the electrodes 22 and comprises several slots to receive each electrode 22. The electrode tip slot 52 may extend partially through the thickness of the collar 16. Thus, in use, the electrode tip slot 52 can protect the distal tips of the electrodes 22 from contacting other nerves or anatomy (e.g., muscles, bones, connective tissue, etc.) that are not targets of the electrodes. [0099] The fingers 50 may be spaced apart along the longitudinal axis 2, providing a gap 58. The gap 58 may be dimensioned to fit the first portion of the length of the collar neck 14 along longitudinal axis 2, without limiting circumferential movement of the collar 16. For example, the gap 58 may be dimensioned to fit the collar package 30, which attaches the collar neck 14 to the collar 16. In this way, the distal end of the collar 16 is permitted to wrap around the proximal end of the collar 16 while the fingers 50 insert into the space 42 between the proximal surface of the proximal end of the collar 16 and the collar neck 14. [00100] One or more of the fingers 50 comprises a fastener 82, which is used to hold the collar 16 in the closed configuration, as will be described in further detail below. For example, the fastener 82 may line the inner surface of each finger 50 adjacent to the gap 58. [00101] Referring now to FIG. 2, a perspective cut-away view of the collar system 10 is shown. In FIG. 2, it is shown that the collar package 30 of the collar neck 14 has a slot 36 that is configured to receive the electrode housing 12. The distal end of the collar package 30 may also have one or more holes or spaces 54 that are dimensioned so that the electrodes 22 can pass distally through the collar neck 14. The holes 54 may extend from the slot 36 through the distal end of the collar neck 14 to the distal surface of the collar neck 14 and may be defined by one or more interior surfaces. For example, distal side of the collar package 30 comprises a single hole (e.g., 54) that fits all of the electrodes 22, several separate holes that each receive one of the electrodes 22, or multiple holes that receive a subset of electrodes 22. The holes 54 may be smaller in area than the proximal opening of the slot 36 such that the distal end of the collar package 30 may hold the electrode housing 12 in place. [00102] Similarly, the proximal end of the collar 16 comprises holes 56 that allow the electrodes to pass distally through the collar 16. The collar holes 56 may extend through the full thickness of the collar 16 from the proximal surface of the proximal end of the collar 16 to the distal surface of the proximal end of the collar 16. The collar 16 comprises a single hole (e.g., 56) that fits all of the electrodes 22, several separate holes that each receive one of the electrodes 22, or multiple holes that receive a subset of electrodes 22. The collar package holes 54 may align with the collar holes 56 such that the electrodes 22 may pass through both the distal end of the collar package 30 and the proximal end of the collar 16. However, while the collar package holes 54 and collar holes 56 may be the same size and shape, they are not required to be so, as some or all of the holes 54 or 56 may be larger than the size of the electrode 22 cross-sectional area. Holes 54 or 56 may be defined by an interior surface and may be vertical or tapered and be oval shaped or squared with rounded or right angled corners. [00103] In use, the electrode housing 12 is slid distally into the slot 36 while the electrodes 22 can pass distally through the collar package holes 54 and the collar holes 56 such that the electrodes 22 engage with the nerve 60, when the nerve 60 is in place. The collar neck 14 further comprises one or more locking feet 70. The locking feet 70 can have a back side facing the inner portion of the slot 36 and a front side opposite of the back side and facing away from the slot 36. The front side may retain a fastener 72. For example, the front side of the locking feet 70 may be lined with grip teeth that are configured to engage with grip teeth lining a portion of the collar fingers 50, as will be described further below. [00104] The locking feet 70 may be flexible and biased towards the slot 36. For example, the locking feet 70 may have flexible legs 74 that extend proximally from the locking feet 70 to connect the locking feet 70 to the collar neck 14 and bias the locking feet 70 towards the slot 36, such that they protrude into the slot 36 when the electrode housing 12 is not in place. The flexible legs 74 may be constructed with a spring or with a flexible material, such as plastic. The flexible legs 74 may allow for the locking feet 70 to be pushed away from the slot 36 when the electrode housing 12 is slid into the slot 36, whereby an outer surface of electrode housing 12 presses against the back side of the locking feet 70, thereby pushing the locking fee away from the slot 36. Such motion may cause the fastener 72 to engage with a complimentary fastener 82 on the collar 16, as will be described in further detail below. [00105] Because the locking feet 70 are biased towards the slot 36, removing the electrode housing 12 may cause the locking feet to retract back into or towards the slot 36, which may disengage the fastener 72 from its complimentary fastener 82. Further, the bias towards the slot 36 of the locking feet 70 creates inward pressure from the back surface side of the locking feet 70 onto the outer surface of the electrode housing 12. This pressure helps maintain the position of the electrode housing 12 relative to the collar neck 14. The electrode housing 12 comprises ridges, teeth or a frictionally engaging outer surface to engage a similar feature on the back surface side of the locking feet 70 and further hold the electrode housing in place relative to the collar neck 14. [00106] The complimentary fasteners 82 may be located on the collar fingers 50, for example along the inner surface of the fingers 50 adjacent to the gap 58. The fasteners 82 may extend along the whole length of the inner surface of the fingers 50, which allows for a variable diameter of the collar 16 in the deployed position (i.e., coiled and wrapped around the nerve 60). When the collar 16 wraps around the nerve 60, a portion of the collar fasteners 82 will align with the collar neck fasteners 72 allowing the fasteners to engage with one another to lock the collar 16 in the coiled and engaged position. These fasteners help to arrest further movement of the collar 16, allowing a surgeon to select a preferred diameter of the deployed collar 16 before instance based on the diameter of the target nerve or nerves 60. [00107] Placement of the electrode housing 12 within the slot 36 can lock the collar 16 into an engaged configuration. The locking function may be achieved by fasteners (e.g., 72 and 82) coupled to the collar 16 and the collar neck 14. In particular, the collar neck 14 may have one or more fasteners 72. For example, the fasteners 72 comprises grip teeth, as shown in Figure 2. The grip teeth may protrude from a surface in a pattern that is inverse to the complimentary receiving fastener 82. As a non-limiting example, the grip teeth surface may have a zig-zagged pattern, wherein the protrusions have a triangular cross section shape, for instance with 60° angles at their peaks, and the grooves are triangular with 60° angles at their base. In this example, the complimentary fastener 82 comprises grip teeth with the same pattern, such that the protrusions of fastener 72 are received by the grooves of the fastener 82, and vice versa. The grip teeth may also have a triangular pattern of different angles. Such triangular shaped protrusions and grooves of the grip teeth may advantageously allow for slight motion in the circumferential direction as the fasteners engage together. In this way, the grip teeth are not required to be perfectly aligned with the complimentary grip teeth when the locking process begins, and they will align by sliding or passing along the surfaces of the triangles. However, the grip teeth may alternatively have protrusions, ridges and grooves of other shapes and sizes, or another frictionally engagement which may be complimentary (i.e., opposite) on the receiving fastener 82. [00108] Referring, to FIG. 3, the collar system 10 is shown in a transitional state between the open configuration to the closed, active or engaged configuration. As FIG. 3 shows, the neural collar system 10 is configured to be used in conjunctional with a surgical device 300 that is used to deploy the neural collar system 10, transitioning the collar 16 from the open configuration to a closed configuration and inserting the electrode housing 12 into the slot. The surgical device 300 comprises a device housing 302, a plunger 304, one or more grip hooks (e.g., 306 and 308), a flexible tongue 310, and a tongue guide 312. For example, the grip hooks comprise opposing grip hooks, such as a proximal grip hook 306 that may be retractable and a distal grip hook 308 that may be stationary. [00109] As previously described, the collar 16 may be provided in an open, hook-like position when undeployed. For example, in the undeployed position, the collar 16 may have a “C”-like shape with round proximal and distal ends connected by a nearly straight mid-section. The collar 16 may be flexible and biased towards the undeployed, open position. It may be constructed from a layer of flexible material, such as nylon or other biocompatible polymer, with a thickness that may be constant or vary along the length of the collar. The thickness of the collar is between 0.5 to 10 millimeters. In an undeployed position, the hook-like fingers 50 of the collar 16 can hook a nerve 60 or nerve bundle to begin engaging the nerve 60. Once the nerve 60 is in place within the open collar 16, the collar 16 is wrapped around the nerve 60 in a circumferential direction. As FIG. 3 shows, the collar 16 is pushed in a circumferential direction by sliding a flexible tongue 310 along a tongue guide 312. This will cause the collar 16 to coil or wrap around the nerve 60, fitting the collar fingers 50 into the space 42 defined by the proximal surface of the proximal end of the collar 16 and the distal surface of a portion of the collar neck 14. The collar 16 may fully surround the circumference of the nerve 60 to keep it in place within the collar system 10. [00110] When the collar 16 is wrapped around the nerve 60, the collar fastener 82, or at least a portion of the collar fastener 82, will be aligned within the space 42 to receive the collar neck fastener 72, thus locking the collar 16 into place around the nerve 60. The electrode housing 12 may be inserted into the slot 36 using the plunger 304. The insertion of the electrode housing 12 will push the locking feet 70 into an engaged position in which the collar neck fastener 72 engages with the collar fastener 82, as previously described. This will maintain the collar 16 in the wrapped position while the electrode housing 12 is in place within the slot 36. Also, while the electrode housing 12 is positioned in the slot 36, the electrodes 22 may engage with the nerve 60 that is positioned within the collar 16. The tips of the electrodes 22 may be received by the electrode tip slot 52 on the distal end of the device. [00111] Referring again to FIG. 2, the collar neck 14 further comprises one or more grip hook recesses 84 that can receive the retractable grip hook 306 of the surgical device 300 for deployment. The grip hook recess 84 may be defined by an inner surface forming a cutout space within the collar neck 14. A distal grip hook 308 may engage with the collar neck 14 by wrapping around a bottom surface or edge of the collar neck 14 and gripping a distal surface or edge of the collar neck 14. [00112] Referring now to FIGs.4-8, the process of deploying the neural collar system 100 is illustrated in one example embodiment including six steps. FIG. 4 demonstrates steps 1-3. First, the electrode housing 12 may be placed within the surgical device 300. Next, the retractable hook 306 of the surgical device 300 may be retracted and the collar system 10 may be inserted into the surgical device 300. The retractable hook 306 may be released distally in order to hold the collar neck 14 between the proximal grip hook 306 and the distal grip hook 308. At this point the collar 16 may be in an open position to receive a nerve 60, multiple nerves, or a nerve bundle. [00113] In step 4, the nerve may be hooked by the collar fingers 50, as shown in FIG. 5. To hook the nerve 60, the surgical device 300 coupled with the collar system 10 may be moved toward the nerve 60 in a radial direction 8 so that the nerve 60 may enter the open collar 16 while rotating the device circumferentially around the nerve 60. The device may then be moved distally to align the nerve 60 in the proximal end of the collar 16 to partially surround the nerve 60. [00114] As shown in FIG. 6, step 5 comprises deploying the flexible tongue 310, which will slide along the inner surface of the tongue guide 312 and the outer surface of the collar 16 in the distal direction. The tongue guide 312 is shaped to create a circular path of the distal end of the flexible tongue 310. Thus, the movement of the flexible tongue 310 along the tongue guide 312 can cause the collar 16 to curl circumferentially to wrap around the nerve 60. Applying force to the collar 16 by the movement of the flexible tongue 310 can cause the collar 16 to wrap around the nerve 60, creating a coiled position with a circumference that encircles the nerve 60. After the collar 16 is deployed into the engaged position (i.e., circumferentially wrapped around the nerve 60), step 6 comprises inserting the electrode housing 12 into the slot 36, as shown in FIG. 7. The electrode housing 12 may be slid proximally down into the slot 36 for instance by pressing down on the plunger (not shown). The insertion of the electrode housing 12 causes the locking feet 70 to move outwardly toward the collar fingers 50 such that the collar neck fasteners 72 engage with the collar fasteners 82. This locks the collar 16 in the engaged position with the selected diameter while the electrodes 22 are embedded into the nerve 60, activating the device for signal transmission to and from the nerve 60. The flexible tongue 310 may be released proximally. [00115] As shown in FIG. 8, once the collar 16 is in the activated and locked position, the retractable grip hook 306 is retracted, releasing the collar system 10 from the surgical device 300. The surgical device 300 may be removed, leaving just the collar system 10 fixed in place around the target nerve 60. The cable boot 34 is snapped into to the collar neck 14 providing secure contact between the electrodes 22 and the data cable 32, or flexible printed circuit board. The cable boot 34 is detachable for cable upgrade or replacement without the need for explanation of the whole collar system 10. [00116] FIG. 9 shows an example of a system 400, which is a specific implementation of the various devices and systems described herein. As such, the system 400 pertains and is applicable to the other devices described herein (and vice versa). In some cases, the system 400 is an implantable neural collar system, similar to the implantable neural collar system. In other cases, the system 400 is an implantable peripheral nerve system. [00117] As shown in FIG.9, the system 400 a probe 402, a probe housing 404, a support, and a cable 408. The probe 402 and the probe housing 404 are implemented in a similar manner as the probe and housing as described in the corresponding application U.S.62/511,101 filed June 29, 2023 and entitled, “Neural Electrode and Related Methods,” which is incorporated by reference in its entirety, including any derivative applications. For example, the probe 402 comprises one or more shanks 410 (e.g., which is defined as an electrode shank because each shank 410 comprises at least one electrode contact), each of which comprises one or more electrode contacts. Correspondingly, the probe 402 further comprises one or more electrode traces and one or more electrical contacts 412. Each electrode contact is electrically coupled to a respective electrode trace, which is electrically coupled to a respective electrical contact (e.g., of the electrical contacts 412). The probe 402 comprises a plurality of electrode shanks, each of which comprises a plurality of electrode contacts, and a plurality of electrode traces each of which electrically couple a given electrode trace of a shank to a corresponding electrical contact of the probe. As shown in FIG. 9, the probe 402 is positioned within the housing 404. For example, the probe housing 404 can include a recess (or stated a different way a slot) with a hole fluidly coupled to the recess. The hole is positioned at the bottom of the probe housing 404. The probe 402 is inserted into the recess of the probe housing 404 and the one or more shanks 410 can extend through the hole and outside of the probe housing 404. In other words, the one or more shanks 410 are positioned outside of the probe housing 404 (e.g., outside the recess of the probe housing 404), such that the probe housing 404 surrounds and secures a portion of the probe 402 (e.g., to protect the probe 402) while the one or more shanks 410 are free to engage (e.g., penetrate) a nerve of a subject. [00118] In one embodiment, the probe housing 404 comprises a locking feature 414 that can prevent or otherwise block movement of the probe housing 404 (e.g., with the probe 402 positioned therein). For example, as shown in FIG.9, the locking feature 414 is implemented as a protrusion, which as described below, engages with a corresponding locking feature of the support 406 to prevent movement of the probe housing 404 relative to the support 406 (e.g., downward translation of the probe housing 404 relative to the view in FIG. 9). In some cases, when the locking feature 414 is implemented as protrusion, the protrusion is a locking tooth. For example, the locking tooth is angled (e.g., can have a triangular side profile) and is inserted into a recess having a similar shape. In other cases, the locking feature 414 is a recess, hole, etc., that engages with a corresponding feature of the support 406. In one embodiment, the locking feature 414 comprises a spring (e.g., compression spring, tortional spring, etc.) that biases a protrusion towards a position where the protrusion extends away from the probe housing 404. Similarly, the collar body 416, and in particular, the extension 446 comprises a recess that receives the protrusion, thereby locking the probe housing 404 into the extension 446 (e.g., the slot 452 of the extension 446). Correspondingly, in some cases, the probe housing 404 is removably coupled to the collar body 416, such as at the extension 446 (e.g., with the spring biased protrusion and recess configuration). [00119] The support is implemented in different ways, including a similar configuration as the collars described herein or the supports and collars of the corresponding provisional application 62/511,101, and derivative applications thereof, incorporated herein by reference in its entirety. The support is configured to surround (e.g., entirely or partially) a nerve of a subject (e.g., a peripheral nerve) and is configured to receive and secure the probe 402 (and probe housing 404) as well as the cable 408. For example, the support comprises a slot with a hole positioned at an end of the slot, in which the slot receives and secures the probe housing 404 with the probe 402 positioned therein. As indicated below, the support will be described as being a collar 406; however, it is appreciated that the support comprises all the features of the collar and is shaped in different ways as the collar 406. [00120] The collar 406 comprises a collar body 416 that defines a bore 418 that receives a nerve (e.g., a peripheral nerve). The collar body 416 comprises portions 420, 422 and a hinge 424 that is coupled to the portions 420, 422. Each portion 420, 422 comprises a curve, or stated another way, each portion 420, 422 can be curved. The portions 420, 422 extend along a longitudinal axis 425 of the collar 406. The longitudinal axis 425 can be perpendicular to a vertical axis 426, which defines distal and proximal directions of the collar 406. Correspondingly, the intersection between the longitudinal axis 425 and the vertical axis 426 defines an origin for a radial axis 428. Further, a circumferential axis 430 is defined around the longitudinal axis 425. The portions 420, 422 of the collar 406 span substantially (i.e., deviating from less than or equal to 30 percent from, in this case, a length) the same length (e.g., along the longitudinal axis 425). For example, the length of the portions 420, 422 can be substantially the same. The portions 420, 422 are coupled to each other, such that when the portions 420, 422 are coupled to each other, the collar 406 is secured to a nerve (e.g., when the nerve is positioned in the bore 418 of the collar 406). [00121] As shown in FIG.9, the portions 420, 422 are pivotally coupled to each other so as to pivot between an open configuration (e.g., the configuration shown in FIG. 9) and a closed configuration. For example, the collar 406 comprises a hinge 424 that is coupled to the portions 420, 422 so as to allow the portions 420, 422 to pivot about the hinge 424. In some cases, the portion 420 pivots about the hinge 424 about the longitudinal axis 425, while the portion 422 pivots about the hinge 424 about the longitudinal axis 425. The hinge 424 is implemented in different ways. For example, the hinge 424 can be a flexible or otherwise compliant material that can bend to permit pivoting of the portions 420, 422. As another example, the hinge 424 comprises a pin (e.g., a pinned connection) to allow the portion 420 to pivot relative to the portion 422 (or vice versa). In one embodiment, the portions 420, 422 can have substantially the same peripheral shape (e.g., taken from the cross-section at the longitudinal axis 425 of the collar 406). For example, each portion 420, 422 can have a u-shape which allows the portions 420, 422 to better engage and secure the nerve within the bore 418 of the collar 406 (e.g., which is defined by the portions 420, 422 of the collar 406). In some cases, and as illustrated in FIG. 9, a peripheral distance 432 of the portion 420 is shorter than a peripheral distance 434 of the portion 422, where each peripheral distance is the length of a line integral that follows the curvature of the respective portion until it terminates at an end. In this way, the portion 422 wraps around or otherwise surround the portion 420, such that the collar 406 surrounds the entire nerve when the nerve is positioned within the collar 406 (e.g., positioned within the bore 418). In some cases, the portion 422 has different curvatures, which accommodates securing the portion 422 to the portion 420 and permits adequate bending or compliance of the hinge 424. For example, the portion 422 has curvature regions 436, 438, each of which are different, and the curvature region 436 can be positioned above the curvature region 438. In some cases, in the closed configuration, the collar body 416 surrounds the nerve tightly enough to prevent axial translation of the collar body 416 along the nerve, but loose enough to prevent undesired pressure on the nerve. [00122] Although the portions 420, 422 have been described as having a u-shape or being substantially u-shaped, the portions 420, 422 can surround the nerve in other ways. For example, each portion 420, 422 can be circular, such as each being a semi-circle or each having a different arc length. Regardless of the configuration, as described above, the portion 422 is coupled to and wraps at least partially around the portion 420 (e.g., with the portion 420, 422 surrounding the nerve). For example, the collar 406 (or broader system 400) comprises a fastener 440 that secures and locks the collar 406 around the nerve. The fastener 440 is implemented in different ways. As shown in FIG. 9, the fastener 440 comprises a tooth 442 and a hook 444, in which the hook 444 engages with the tooth 442 to lock the fastener 440. In some cases, and as illustrated, the portion 420 comprises the tooth 442, while the portion 422 comprises the hook 444. However, in other configurations, the portion 422 comprises the tooth 442 and the portion 420 comprises the hook 444. The tooth 442 is positioned at a free end of the portion 420, while the hook 444 is positioned at a free end of the portion 422. More specifically, the tooth 442 is positioned on an exterior surface the portion 420, opposite an interior surface that at least partially defines the bore 418. In some cases, the portion 420 is fixed, and the portion 422 pivots about the hinge 424 towards the portion 420 until the hook 444 engages with the tooth 442 and locks the portion 422 to the portion 420. Although the fastener 440 has been described as being a hook and tooth, the fastener 440 is implemented as other fasteners including threaded fasteners, hook and loop fasteners, adhesives, magnets (e.g., the portions 420, 422 being magnetically coupled to each other), etc. [00123] In one embodiment, a width or a diameter of the bore 418 is adjustable so as to permit entry and securement of different sized nerves. For example, the diameter of peripheral nerves varies, depending on the location of the nerve. In particular, as the peripheral nerve emanates from the central nervous system and towards the periphery, the peripheral nerve gets smaller in diameter. Therefore, the collar 406 being adjustable is advantageous so as to allow the collar 406 to be secured to various sizes of nerves. To that end, as shown in FIG. 9, the fastener 440 accommodates a plurality of different positions, each of which defines a different width or diameter of the bore 418. For example, the fastener 440 comprises a plurality of teeth (e.g., two, three, four, etc.) with each tooth defining a different locking position that has a different width or diameter of the bore 418. In particular, when the hook 444 engages a first tooth of the plurality of teeth, the collar 406 is locked in a first closed configuration where the bore 418 has a first width. Correspondingly, when the 444 engages a second tooth of the plurality of teeth, the collar 406 is locked in a second closed configuration where the bore 418 has a second width. In this case, the second width is different than the first width (e.g., larger than the first width). [00124] In one embodiment, the collar body 416 comprises an extension 446. The extension 446 is positioned at a top of the collar body 416, such that the extension 446 is positioned above the nerve when the nerve is positioned within the bore 418. In some cases, the extension 446 is coupled to the first portion 420 of the collar body 416 and extends above the first portion 420. For example, as shown in FIG. 9, the extension 446 is integrally formed with the portion 420 of the collar body 416 (e.g., the components form a a single monolithic component). In some cases, the extension 446 separates the portion 420 into two sections, with a first section being positioned on one side of the extension 446 and another section being positioned on an opposing side of the extension 446, where each side is a longitudinal side. Therefore, each section of the portion 420 can be curved, can have a u-shape, semi-circular shape, partial circular shape, etc. In some cases, the extension 446 can bisect the portion 420. [00125] The extension 446 comprises seats 448, 450, positioned on opposite sides of the extension 446 (e.g., opposing transverse sides, in a direction transverse to the longitudinal axis 425). For example, the nerve or bore 418 is positioned between the seats 448, 450. The seats 448, 450 can be angled, beveled, etc., which can extend downwardly towards the nerve. Each seat 448, 450 receives a corresponding feature of the cable 408 to couple the cable 408 to the extension 446. The collar body 416, and in particular the extension 446, comprises a slot 452 directed into the extension 446 that receives the probe housing 404 to secure the probe housing 404 therein (e.g., with the probe 402 secured by the probe housing 404). Further, the collar body 416, and again, more specifically the extension 446 comprises a hole 454 directed through the collar body 416. The hole 454 provides access, such that the one or more shanks 410 of the probe 402 extends through the hole 454 and engage with to be electrically coupled to a nerve (e.g., a peripheral nerve) secured, trapped, etc., by the collar 406. In some cases, and as shown in FIG. 9, the hole 454 is fluidly coupled to the slot 452 and is positioned at an end (e.g., a bottom end) of the slot 452. In this way, the slot 452 secures the probe housing 404, while the one or more shanks 410 extend through the hole 454 into the bore 418 (e.g., to engage, penetrate, etc., the nerve therein). In some cases, advantageously, the slot 452 is oriented such that a width extends substantially along a transverse axis of the collar 406 (e.g., perpendicular to the longitudinal axis 425, such that the transverse axis straddles the longitudinal axis 425), which ensures that each shank is positioned at a different transverse location along a nerve thereby allowing for the collection of more unique nerve signals (e.g., all the shanks being within substantially the same axial cross section of the nerve). [00126] In one embodiment, the collar 416 comprises a protrusion 456. Similarly to the extension 446, the protrusion 456 is positioned on a top of the collar body 416, such that the protrusion 456 extends above the bore 418 and above the nerve positioned therein. As shown in FIG. 9, the protrusion 456 extends above the extension 446. For example, the protrusion 456 extends away from and above the collar body 416 including the seats 448, 450 of the extension 446. In some cases, the protrusion 456 is coupled to the extension 446. In other cases, the protrusion 456 is integrally formed with the extension 446 (e.g., the protrusion 456 and the extension 446 forming a single monolithic component). In some configurations, a wall of the protrusion 456 at least partially defines the slot 452. In this way, the protrusion 456 supports the probe housing 404 (e.g., with the probe 402 therein). For example, the probe housing 404 contacts the protrusion 456 (e.g., at a wall thereof), when the probe housing 404 (and the probe 402) is positioned within the slot 452. [00127] In one embodiment, the collar body 416, and in particular the extension 446, comprises an engagement feature 458. The engagement feature 458 interfaces with an arm of a device (e.g., a surgical device, such as the surgical device 300) that engages with the collar 406 and closes the collar 406 around a nerve. More specifically, the engagement feature 458 increases the friction between the collar body 416 (and particular the extension 446) and an arm of a device so as to ensure that the arm maintains contact with the collar body 416 (e.g., at the extension 446) and prevents slipping or disengagement with the arm of the device. The engagement feature 458 is implemented in different ways. For example, the engagement feature is a recess, a hole, a rough surface, a number of small protrusions emanating from the surface of the collar body 416 at the location, etc. Although the engagement feature 458 is shown on one side of the extension 446, the other side of the extension 446 comprises an engagement feature (e.g., implemented in a similar was to the engagement feature 458). [00128] As shown in FIG.9, the collar body 416, and in particular the portion 422 comprises a hole 460, or in some cases a recess, that receives the one or more shanks 410 of the probe 402, which are implemented in a similar way as the electrode tip slot 52 of the collar 16. For example, each tip (e.g., the sharp termination point of a free end of a shank) of each shank 410 is received in the hole 460, which prevents the tips from penetrating other tissues. As described with reference to slot 52, although the hole 460 has been described has being a recess, in some cases, the collar body 416 comprises a plurality of recesses (or holes) each of which receives a respective shank of a plurality of shanks of the probe 402. [00129] In some configurations, and as described in more detail below, the cable 408 comprises a cable boot 462 coupled to and positioned at an end of the cable 408 (e.g., a terminal end of the cable 408 that comprises one or more wires therein). The cable boot 462 is coupled to (and removably coupled) to the collar body 416, and in particular, the extension 446 and protrusion 456 of collar body 416. More specifically, when the probe housing 404 with the probe 402 therein is positioned within the slot 452 of the collar body 416, the cable boot 462 is coupled to the collar body 416 and at least partially surrounds the probe housing 404. In this way, the cable boot 462 locks the probe housing 404 into the collar body 416 thereby constraining relative movement between the probe housing 404 and the cable boot 462. [00130] FIG.10 shows an example of a cross-section of the system 400 with the collar in a closed configuration around the nerve (e.g., a nerve bundle) and prior to the insertion of the probe into the collar. In particular, the collar 406 surrounds the entire circumferential extent of a nerve bundle 464. For example, the portion 422 partially overlaps with the portion 420, where the hook 444 is engaged with the corresponding tooth 442 to lock the collar 406 into a closed position, such as the one shown in FIG.10. In some cases, the nerve bundle 464 (e.g., a peripheral nerve bundle), and in particular a top of the nerve bundle 464, extends at least partially through the hole 454 in the extension 446. In this way, the nerve bundle 464 is further secured by the collar 406 and ensures that the one or more shanks 410 engage (e.g., penetrate) the peripheral nerve bundle 464). In some cases, when in the closed configuration, the hinge 424 flexes inward to contact opposing portions of the hinge 424 (e.g., the hinge 424 pressing against itself). As illustrated in FIG. 10, the probe housing 404 with the probe 402 therein is aligned with the slot 452 for insertion therein. [00131] In one embodiment, the collar body 416, and more specifically, the extension 446 and the protrusion 456 of the collar body 416, comprises a slot, which vertically extends down towards the nerve bundle 464 (or towards the portions 420, 422). This slot receives the locking feature 414 of the probe housing 404, when, for example, the locking feature is implemented as a locking tooth. When the probe housing 404 is inserted into the slot 452 of the collar 406, the locking feature 414 of the probe housing 404 is received in the slot. In this way, side to side movement (e.g., in a transverse direction) of the probe housing 404 relative to the collar 406 is blocked by the engagement between the locking feature 414 of the probe housing 404 and the collar 406. Although the slot is illustrated as being rectangular, the slot is implemented in different shapes. Further, although the collar body 416 is shown as having a slot, this slot can be replaced with a complementary feature of the locking feature 414. For example, if the locking feature 414 is implemented as a recess, the slot is implemented as a protrusion. Stated another way, the collar 406 comprises the locking feature 414 that engages with a corresponding feature of the probe housing 404 to secure the probe housing 404 relative to the collar 406. [00132] FIG.11 shows an example of a cross-section of the system 400 with the collar in a closed configuration around the nerve (e.g., a nerve bundle) and with the probe inserted into the collar. In particular, the probe housing 404 with the probe 402 therein is inserted or otherwise positioned within the slot 452 of the collar body 416 (and more specifically the extension 446). At this point, the one or more shanks 410 of the probe 402 extend through the hole 454 and puncture or otherwise are inserted into the nerve bundle 464. For example, as shown in FIG.11, the probe 402 including four shanks extend across a cross-section (e.g., an axial cross-section) of the nerve bundle 464, which allows each electrode contact (of a plurality or many electrode contacts) on each shank to interface or electrically couple with a different nerve fiber, thereby collecting more unique nerve signals or allowing the different nerve fibers to be selectively excited. In some cases, and as illustrated in FIG. 11, each terminal end tip of the one or more shanks 410 is inserted into the hole 460, as described above. In some configurations, a portion (e.g., a top portion) of the probe housing 404 (and the probe 402) are positioned above each seat 448, 450. Further, this portion of the probe housing 404 is flush with the protrusion 456. For example, a top of the probe housing 404 is flush with a corresponding top of the protrusion 456. [00133] FIG.12 shows an example of a cross-section of the system 400 with the collar in a closed configuration around the nerve (e.g., a nerve bundle), with the probe inserted into the collar, and with the cable boot coupled to the collar. As shown in FIG. 12, the cable boot 462 comprises arms 466, 468 which extends away from the cable 408. The arms 466, 468 are positioned on opposing sides of the cable 408, such that the cable 408 is positioned between the arms 466, 468. In this way, the arms 466, 468 and the cable boot 462 can form a u-shape. As described above, the cable boot 462 is coupled to the collar 406, and more specially the collar body 416. For example, the system 400 comprises one or more fasteners that are configured to couple the cable boot 462 to the collar 406. As a more specific example, the system 400 comprises fasteners 470, 472, each of which are configured to fasten, couple, etc., the cable boot 462 to the collar 406. In some cases, each fastener 470, 472 is formed by part of the cable boot 462 and the collar body 416. For example, the fastener 470 comprises a tooth 474 on the arm 468, while the fastener 472 comprises a tooth 476 at the arm 468. The teeth 474, 476 can face each other, with the tooth 474 extending towards the probe housing 404 and with the tooth 476 extending towards the probe housing 404. The teeth 474, 476 are received in a corresponding recess of the collar body 416 to couple the teeth 474, 476 to the collar body 416. For example, each fastener 470, 472 comprises a respective recess 478, 480. For example, the collar body 416, and specifically the protrusion 456, comprises recesses 478, 480, where the tooth 474 is inserted into the recess 478 and where the tooth 476 is inserted into the recess 480. The engagement between the teeth 474, 476 and corresponding recesses 478, 480 lock the cable boot 462 to the collar body 416, by, for example, a snap-fit connection between the two components. Although the fasteners 470, 472 have been described as being a protrusion on an arm and a recess of the collar body, these are implemented in a vice versa way (e.g., a protrusion on collar body and a recess on an arm). [00134] In one embodiment, the engagement between the cable boot 462 and the collar body 416 ensures that the probe 402 is prevented or otherwise blocked from moving relative to the nerve bundle 464. For example, the probe housing 404 surrounds the probe 402, the collar body 416 (e.g., the extension 446 and the protrusion 456) surrounds the probe housing 404 (e.g., with the probe 402 therein), and the cable boot 462 surrounds the probe housing 404 and a portion of the collar body 416 (e.g., the protrusion 456, such as with the arms 466, 468, the extension 446, etc.). This nesting configuration ensures that the probe 402 is secured relative to the nerve bundle 464 (e.g., the probe 402 does not slide out of the slot 452). To that end, each arm 466, 468 extends downwardly (e.g., towards the nerve bundle 464), engages and contacts the respective seats 448, 450 of the extension 446, which provides further support for the cable boot 462. In one embodiment, and as illustrated in FIG.12, the cable boot 462, the protrusion 456 and the extension 446 are flush (e.g., a top of each of these components are flush). Further, the outer periphery of the cable boot 462, the protrusion 456 and the extension 446 when assembled are be smooth, free of sharp edges, etc., so as to minimize inadvertent rection with surrounding tissue. [00135] Although not shown in FIG.12, when the cable boot 462 couples to the collar body 416 and the probe housing 404, the cable 408 electrically couples to the probe 402. For example, one or more electrical contacts of the cable 408 are brought into engagement with the one or more corresponding electrical contacts 412 positioned on a top of the probe 402. In this way, electrical signals are transmitted from the cable 408 to the probe 402 (e.g., for nerve stimulation) or electrical signals are transmitted from the probe 402 to the cable 408 (e.g., for nerve signal interpretation). [00136] In one embodiment, portions of or the entire system 400 are implanted in the subject. For example, the probe 402, probe housing 404, collar 406, and cable 408 (e.g., including the cable boot 462) are implanted within the subject, for example, under the skin of the subject. This implantation of the system 400 allows for prolonged usage of the system 400. In other configurations, the implantation of the system 400 is temporary, such as during harvesting of neural signals. To that end, some or all of the components of the system 400 that are coupled together are removably coupled together. For example, the cable boot 462 is removably coupled from the collar body 416 (e.g., at the protrusion 456 of the collar body 416) and the probe housing 404 is removably coupled to the collar body 416 (e.g., by removing the probe housing 404 (e.g., with the probe therein 402) from the slot 452 of the collar body 416. [00137] FIG. 13 shows an example of the system 400 in the open configuration being deployed by an instrument or tool, while FIG. 14 shows an example of the system 400 in the closed configuration being deployed by the instrument or tool. As shown in FIG.13, the tool locks the collar body around a nerve prior to, or during advancement or insertion of the probe housing into the collar body . Correspondingly, FIG.14 shows the tool locking the collar body around the nerve, while inserting the probe housing into the collar body. [00138] While the invention has been described with reference to certain exemplary embodiments thereof, those skilled in the art may make various modifications to the described embodiments of the invention without departing from the scope of the invention. The terms and descriptions used herein are set forth by way of illustration only and not meant as limitations. In particular, although the present invention has been described by way of examples, a variety of devices would practice the inventive concepts described herein. Although the invention has been described and disclosed in various terms and certain embodiments, the scope of the invention is not intended to be, nor should it be deemed to be, limited thereby and such other modifications or embodiments as may be suggested by the teachings herein are particularly reserved, especially as they fall within the breadth and scope of the claims here appended. Those skilled in the art will recognize that these and other variations are possible within the scope of the invention as defined in the following claims and their equivalents. REFERENCES US Patent No.10136825 filed January 14, 2014 titled “Long-term implantable silicon carbide neural interface device using the electrical field effect”. US Patent No. 9211401 filed May 24, 2012 titled “Cubic silicon carbide implantable neural prosthetic”. International Application No. PCT/US2022/014632 filed January 31, 2022 titled “Electrode device and related methods”. Graphene electrodes on a planar cubic silicon carbide (3C-SiC) long term …WO US US8751015B2 Stephen E. Saddow University of South Florida Implantable biocompatible SiC sensors WO US WO2013138275A1 Stephen E. Saddow University of South Florida

Claims

CLAIMS What is claimed is: 1. A system comprising: a collar configured to at least partially wrap around a nerve, the collar comprising a first portion and a second portion pivotally coupled to the first portion; wherein the collar is configured to pivot between an open configuration and a closed configuration; and wherein, in the closed configuration, the second portion couples to the first portion to secure the nerve within the collar.

2. The system of claim 1, further comprising a fastener configured to couple the first portion and the second portion together.

3. The system of claims 1 to 2, wherein the fastener is adjustable, such that a width of a bore defined by the collar is adjustable; and wherein the first portion and the second portion define the bore of the collar.

4. The system of claims 1 to 3, wherein the fastener comprises a tooth coupled to the first portion of the collar and a hook coupled to the second portion of the collar; wherein the hook engages with the tooth to lock the collar in the closed configuration.

5. The system of claims 1 to 4, wherein the tooth is a first tooth; wherein the fastener comprises a second tooth disposed above the first tooth; wherein when the hook engages the first tooth to lock the collar in the closed configuration, the bore has a first width; and wherein when the hook engages the second tooth to lock the collar in the closed configuration, the bore has a second width, the second width being smaller than the first width.

6. The system of claims 1 to 5, wherein the first portion is configured to pivot about a longitudinal axis of the collar; and wherein the first portion is configured to pivot about the longitudinal axis of the collar; and wherein the longitudinal axis of the collar is substantially parallel to the nerve.

7. The system of claims 1 to 6, further comprising a hinge that is coupled to the first portion and the second portion of the collar; wherein the hinge extends along the longitudinal axis of the collar.

8. The system of claims 1 to 7, wherein, in the closed configuration, the first portion and the second portion of the collar surround an entire circumference of the nerve; and wherein the nerve is a peripheral nerve.

9. The system of claims 1 to 8, wherein the first portion has a u-shape; wherein the second portion has a u-shape; and wherein a portion of the second portion of the collar wraps around the first portion of the collar when the collar is in the closed configuration.

10. The system of claims 1 to 9, wherein in the open configuration, a gap is positioned between a first end of the first portion of the collar and a second end of the second portion of the collar; and wherein the gap permits entry of the nerve into the bore of the collar when the collar is in the open configuration.

11. The system of claims 1 to 10, wherein in the closed configuration, the collar is secured around the nerve, such that the collar is prevented from translating along the length of the nerve.

12. The system of claims 1 to 11, wherein the collar comprises an extension; wherein the extension is coupled to and positioned on top of the first portion of the collar; and wherein the extension segments the first portion of the collar into a first section on one side of the extension and a second section on the opposing side of the extension.

13. The system of claims 1 to 12, wherein the extension of the collar comprises a slot configured to receive a probe and a hole at the bottom of the slot; wherein when the probe is positioned within the slot, one or more shanks of the probe pass through the hole and electrically couple to the nerve.

14. The system of claims 1 to 13, wherein the slot has a width that is adapted to receive a probe housing that secures the probe therein.

15. The system of claims 1 to 14, wherein the extension has a protrusion that comprises one or more fasteners that engage with one or more opposing fasteners of a cable boot of a cable; and wherein engagement between respective fasteners of the extension and the cable boot couple the cable boot to the collar.

16. The system of claims 1 to 15, wherein the one or more fasteners of the protrusion comprises a first extension fastener and a second extension fastener; wherein the protrusion of the extends past opposing sides of the extension to define a first seat and a second seat; wherein the cable boot comprises a first arm on one side of the cable boot and a second arm on the opposite side of the cable boot; wherein the cable boot comprises a first arm fastener on the first arm and a second arm fastener on the second arm; wherein when the cable boot of the cable engages with the protrusion, the first arm of the cable boot engages with the first seat of the extension and the second arm of the cable boot engages with the second seat of the extension; and wherein when the cable boot of the cable engages with the protrusion, the first arm fastener engages with the first extension fastener and the second arm fastener engages with the second extension fastener to couple the cable boot to the extension.

17. The system of claims 1 to 16, wherein a cable boot of a cable is configured to be coupled to a body of the collar; and wherein in the closed configuration with the cable boot of the cable coupled to the body of the collar, a width of the cable boot is greater than a width of the first portion of the collar and the second portion of the collar; and wherein the cable boot is wider than the cable.

18. The system of claims 1 to 17, wherein the probe is attached to a two-piece cable consisting of a first piece, cable A, and a second piece, cable B wherein, cable A and cable B both have a first end and a second end.

19. The system of claims 1 to 18, wherein cable A comprises a percutaneous sensor wire wherein the sensor wire is a multi-strand sensor wire encased in silicone at the first end; and wherein the sensor wire has an electrical connector at the second end.

20. The system of claims 1 to 19, wherein cable B comprises an electrode implant at the first end; and wherein the electrode implant consists of an electrical connector at the fist end, attached by a polyamide cable to an electrode at the second end.

21. The system of claims 1 to 20, wherein cable A is attached to cable B with the electrical connectors.

22. A system comprising: a collar configured to at least partially wrap around a nerve, the collar comprising a first portion and a second portion pivotally coupled to the first portion, the collar is configured to pivot between an open configuration and a closed configuration, in the closed configuration, the second portion couples to the first portion to secure the nerve within the collar, and wherein the collar comprises a slot and a hole fluidly coupled to the slot; a probe comprising at least one shank; a probe housing surrounding the probe, wherein the probe housing is insertable into the probe housing, such that the at least one shank is inserted through the hole and engages with the nerve of a subject thereby electrically coupling the nerve to the at least one shank; a cable comprising a cable boot coupled to an end of the cable, the cable boot being configured to be coupled to the collar with the probe housing, comprising the probe therein, positioned within the slot of the collar; and wherein when the cable boot is coupled to the collar, the cable boot constrains movement of the probe housing relative to the collar.

23. The system of claim 22, wherein the collar wraps around nerves with different diameters.

24. The system of claims 22-23, wherein the nerve is selected from the group consisting of a child’s nerve, an adult’s nerve, a vagus nerve, a leg nerve, an arm nerve, a kidney nerve and any other nerve located in the body of a mammal.

25. The system of claims 22-24, wherein the probe housing comprises a protrusion; wherein the collar comprises a recess; and wherein when the probe housing is inserted into the slot of the collar, the protrusion of the probe housing inserts into the recess of the collar to prevent translation of the probe housing relative to the collar.

26. A method comprising the steps of: wrapping a collar around a peripheral nerve of a subject; inserting a probe housing with a probe therein into a body of the collar while the peripheral nerve is positioned within the bore of the collar; inserting one or more shanks of the probe through the collar until the one or more shanks engage with and electrically couple to the peripheral nerve of the subject; coupling a cable boot of a cable to collar while the probe housing with the probe therein is positioned within the collar; and at least one of: sensing, using the one or more shanks, an electrical signal from the peripheral nerve, the electrical signal being transmitted through the cable; or transmitting, using the cable, an electrical signal to the one or more shanks to stimulate the peripheral nerve.

27. The method of claim 26, wherein wrapping the collar around the peripheral nerve of a subject comprises: opening the collar by pivoting a first portion and a second portion of a collar about a hinge of the collar; placing the peripheral nerve into the collar, while the collar is open; and coupling the collar to itself with the peripheral nerve positioned within a bore of the collar.

28. The method of claims 24-27, wherein the collar has a different diameter depending on the diameter of the nerve.

29. The method of claims 24-28, wherein the peripheral nerve is selected from the group consisting of a child’s nerve, an adult’s nerve, a vagus nerve, a leg nerve, an arm nerve, a kidney nerve and any other nerve located in the body of a mammal.