WO2024000232A1 - A method and a computing device for evaluating protection effect of a protector composition to be applied on keratin materal of a user - Google Patents

A method and a computing device for evaluating protection effect of a protector composition to be applied on keratin materal of a user Download PDF

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Publication number
WO2024000232A1
WO2024000232A1 PCT/CN2022/102230 CN2022102230W WO2024000232A1 WO 2024000232 A1 WO2024000232 A1 WO 2024000232A1 CN 2022102230 W CN2022102230 W CN 2022102230W WO 2024000232 A1 WO2024000232 A1 WO 2024000232A1
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Prior art keywords
test area
parameter value
keratin material
user
self
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PCT/CN2022/102230
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French (fr)
Inventor
Danwen WU
Fengjie SU
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LOreal SA
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LOreal SA
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Priority to PCT/CN2022/102230 priority Critical patent/WO2024000232A1/en
Priority to CN202280097601.1A priority patent/CN119584913A/en
Priority to FR2208090A priority patent/FR3137455B1/en
Publication of WO2024000232A1 publication Critical patent/WO2024000232A1/en
Anticipated expiration legal-status Critical
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/44Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
    • A61B5/441Skin evaluation, e.g. for skin disorder diagnosis
    • A61B5/445Evaluating skin irritation or skin trauma, e.g. rash, eczema, wound, bed sore
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0077Devices for viewing the surface of the body, e.g. camera, magnifying lens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/44Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
    • A61B5/441Skin evaluation, e.g. for skin disorder diagnosis
    • A61B5/443Evaluating skin constituents, e.g. elastin, melanin, water
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/16Emollients or protectives, e.g. against radiation

Definitions

  • the disclosure relates to the field of cosmetics. More specifically, the disclosure relates to a method and a computing device for evaluating protection effect of a protector composition to be applied on keratin material of a user.
  • a method for evaluating protection effect of a protector composition to be applied on keratin material of a user comprises applying the protector composition on a first test area of keratin material of the user; applying an inducer agent which will cause redness and/or discomfort for keratin material of the user above the applied protector composition; removing the applied protector composition and the applied inducer agent from the first test area; imaging the first test area by an imaging device to obtain a first parameter value;
  • the method also comprises obtaining a first self-perceived sensation information for the first test area from the user after the step of removing the applied protector composition and the applied inducer agent from the first test area; and evaluating protection effect based on the first parameter value, the second parameter value and the first self-perceived sensation information.
  • the method also comprises applying the inducer agent on a second test area of the user directly; removing the applied inducer agent from the second test area; imaging the second test area by the imaging device to obtain a third parameter value; measuring the second test area by the device for testing transepidermal water loss of the keratin material to obtain a fourth parameter value; and evaluating protection effect by comparing the first parameter value and the third parameter value and comparing the second parameter value and the fourth parameter value.
  • the method also comprises obtaining a first self-perceived sensation information for the first test area after the step of removing the applied protector composition and the applied inducer agent from the first test area; obtaining a second self-perceived sensation information for the second test area from said user after the step of removing the applied inducer agent from the second test area; wherein the evaluating step also comprises evaluating protection effect based on comparing result between the first parameter value and the third parameter value, comparing result between the second parameter value and the fourth parameter value and comparing result between the first self-perceived sensation information and the second self-perceived sensation information.
  • a computing device for evaluating protection effect of a protector composition to be applied on keratin material of a user comprises an imaging device including computational circuitry configured to image a first test area of keratin material of the user to obtain a plurality of first images; a measurement unit including computational circuitry configured to measure the first test area to obtain a second parameter value; and a processor including computational circuitry configured to process the plurality of first images for the first test area to obtain a first parameter value and evaluate protection effect based on the first parameter value and the second parameter value; wherein before imaging the first test area, the first test area is applied a protector composition; then is applied an inducer agent which will cause redness and/or discomfort for keratin material of the user above the applied protector composition; finally the applied protector composition and the applied inducer agent are removed from the first test area.
  • the processor includes computational circuitry configured to also receive a first self-perceived sensation information for the first test area from the user after the applied protector composition and the applied inducer agent are removed from the first test area; and evaluate protection effect based on the first parameter value, the second parameter value and the first self-perceived sensation information.
  • the imaging device includes computational circuitry configured to also image a second test area to obtain a plurality of second images; the measurement unit includes computational circuitry configured to measure the second test area to obtain a fourth parameter value; and the processor includes computational circuitry configured to process the plurality of second images for the second test area to obtain a third parameter value and to evaluate protection effect by comparing the first parameter value and the third parameter value and comparing the second parameter value and the fourth parameter value; before imaging the second test area, the second test area is applied the inducer agent directly; then the applied inducer agent is removed from the second test area.
  • the processor includes computational circuitry configured to receive a first self-perceived sensation information for the first test area from the user after the applied protector composition and the applied inducer agent are removed from the first test area and also receive a second self-perceived sensation information for the second test area from said user after the applied inducer agent is removed from the second test area; and evaluate protection effect based on comparing results between the first parameter value and the third parameter value, comparing results between the second parameter value and the fourth parameter value; and comparing results between the first self-perceived sensation information and the second self-perceived sensation information.
  • the step of imaging is performed by an imager device and the step of measuring is performed by a device for testing transepidermal water loss of the keratin material.
  • the first test area and the second test area can be one of ear back, forearm and any area of the keratin material.
  • the first parameter value and the third parameter value are redness values of the keratin material; the second parameter value and the fourth parameter value are transepidermal water loss values of the keratin material and the first and the second self-perceived sensation information are information related to itching, burning and stinging.
  • the step of removing the applied protector composition and the applied inducer agent from the first test area is performed in about 5-15mins after the steps of applying an inducer agent which will cause redness and/or discomfort for keratin material of the user above the applied protector composition.
  • the step of removing the applied inducer agent from the second test area is performed in about 5-15mins after the steps of applying the inducer agent on a second test area directly.
  • the protector composition is applied in about 0.01g-0.1g/cm 2 and the inducer agent is applied in about 0.1g-1g/cm 2 .
  • a computer readable medium having stored thereon instructions that when executed cause a computing device to perform the method according to the first aspect of the disclosure.
  • a method for evaluating protection effect of a plurality of different protector compositions to be applied on keratin material of a user comprising the steps of: applying each of the plurality of different protector compositions on each of a first plurality of test areas in ear back of the user and on each of a second plurality of test areas in forearm of the user respectively; applying inducer agents which will cause redness and/or discomfort for keratin material of the user above each of the applied different protector compositions respectively; removing the applied different protector compositions and the applied inducer agents from the first plurality of test areas and from the second plurality of test areas respectively; imaging the first plurality of test areas by an imaging device to obtain a first plurality of parameter values; measuring the second plurality of test areas by a device for testing transepidermal water loss value of the keratin material to obtain a second plurality of parameter values; and evaluating protection effect based on the first plurality of parameter values and the second plurality of parameter values
  • the method also comprises the steps of obtaining a first plurality of self-perceived sensation information for the first plurality of test areas from the user after the step of removing the applied different protector compositions and the applied inducer agents from the first plurality of test areas; and evaluating protection effect based on the first plurality of parameter values, the second plurality of parameter values and the first plurality of self-perceived sensation information.
  • the method also comprises the steps of applying the inducer agents on a third test area in ear back of the user and on a fourth test area in forearm of the user directly; removing the applied inducer agents from the third test area and the fourth test area; imaging the third test area by the imaging device to obtain a third parameter value; measuring the fourth test area by the device for testing transepidermal water loss of the keratin material to obtain a fourth parameter value; and evaluating protection effect by comparing the first plurality of parameter values and the third parameter values and comparing the second plurality of parameter values and the fourth parameter value.
  • the method also comprises the steps of obtaining a third self-perceived sensation information for the third test area after the step of removing the applied inducer agent from the third test area; wherein the evaluating step also comprising evaluating protection effect by comparing the first plurality of parameter values and the third parameter values; comparing the second plurality of parameter values and the fourth parameter value; and comparing the first plurality of self-perceived sensation information and the third self-perceived sensation information.
  • the first plurality of parameter values and the third parameter value are redness values of the keratin material in ear back; the second plurality of parameter values and the fourth parameter value are transepidermal water loss values of the keratin material in forearm.
  • the steps of removing are performed in about 5-15mins after the steps of applying the inducer agents above the applied different protector compositions on the first plurality of test areas and on the second plurality of test areas and applying the inducer agents on the third test area and on the fourth test area directly.
  • the first plurality of self-perceived sensation information and the third self-perceived sensation information are information related to itching, burning and stinging.
  • the different protector compositions are applied in about 0.01g-0.1g/cm 2
  • the inducer agents are applied in about 0.1g-1g/cm 2 .
  • an objective and subjective evaluation for protector composition to be applied on keratin material of the user can be achieved in a fast and more efficient manner, thus a more accurate and quantified evaluation result can be obtained.
  • Fig. 1 illustrates a flowchart of a method 100 of evaluating protection effect of a protector composition to be applied on keratin material of a user in accordance with a first embodiment of a first aspect of the present disclosure
  • Fig. 2 illustrates a flowchart of a method 200 of evaluating protection effect of a protector composition to be applied on keratin material of a user in accordance with a second embodiment of a first aspect of the present disclosure
  • Fig. 3 illustrates a flowchart of a method 300 of evaluating protection effect of a protector composition to be applied on keratin material of a user in accordance with a third embodiment of a first aspect of the present disclosure
  • Fig. 4 illustrates a flowchart of a method 400 of evaluating protection effect of a protector composition to be applied on keratin material of a user in accordance with a fourth embodiment of a first aspect of the present disclosure
  • Fig. 5 illustrates a block diagram of a computing device 500 of evaluating protection effect of a protector composition to be applied on keratin material of a user in accordance with a second aspect of the present disclosure.
  • the present technology may be embodied in hardware and/or in software (including firmware, resident software, micro-code, etc. ) .
  • the present technology may take the form of a computer program product on a computer-usable or computer-readable storage medium having computer-usable or computer-readable program code embodied in the medium for use by or in connection with an instruction execution system.
  • a computer-usable or computer-readable medium may be any medium that may contain, store, communicate, propagate, or transport the program for use by or in connection with the instruction execution system, apparatus, or device.
  • the inventive concept is to evaluate protection effect of a protector composition to be applied on keratin material of a user more particularly in terms of redness values and discomfort for keratin material.
  • Fig. 1 illustrates a flowchart of a method 100 of evaluating protection effect of a protector composition to be applied on keratin material of a user in accordance with a first embodiment of a first aspect of the present disclosure.
  • some actions should be prepared.
  • the user is not allowed to use any cosmetics (including routine skin care products) on back ear 24 hours before the test and is not allowed to take sauna or bath.
  • the user Before testing, the user should know written informed consent and complete inclusion/non-inclusion criteria (primary eligibility) and medical history.
  • the user When testing, the user should clean back ear test area with water and pat dry with paper towel; wait in a constant temperature and humidity environment for 30 minutes.
  • a protector composition is applied on a first test area of keratin material of the user.
  • the protector composition can be a protection product for keratin material of the user.
  • the test area can be one of ear back, forearm and any area of the user body.
  • the protector composition is applied in about 0.01g-0.1g/cm 2 .
  • an inducer agent which will cause redness and/or discomfort for keratin material of the user is applied above the applied protector composition.
  • the inducer agent can be those with high pH ingredient and risk to induce keratin material redness, and discomfort.
  • the inducer agent is applied in about 0.1g-lg/cm 2 .
  • the applied protector composition and the applied inducer agent is removed from the first test area.
  • the block 103 is performed in a predefined time period after the block 102.
  • the predefined time period can be from 5mins to 30mins, preferably from 5mins-15mins.
  • the first test area is imaged by an imaging device to obtain a first parameter value. More particularly, in order to obtain more accurate result, the first test area is imaged by the imaging device more times to obtain a plurality of first images and then the plurality of first images are processed to obtain redness value for keratin material.
  • such imaging device can be a camera, a mobile phone with imaging capability, a notebook with imaging capability and so on.
  • the first test area is measured to obtain a second parameter value.
  • block 105 can be performed by a device for testing transepidermal water loss of the keratin material and the second parameter value can be transepidermal water loss values of the keratin material. Order of performing blocks 104, 105 can be exchanged.
  • protection effect is evaluated based on the first parameter value and the second parameter value. By method 100, protection effect such as in terms of redness and discomfort of protector composition for keratin material can be obtained in a fast and an objective manner.
  • Fig. 2 illustrates a flowchart of a method 200 of evaluating protection effect of a protector composition to be applied on keratin material of a user in accordance with a second embodiment of a first aspect of the present disclosure.
  • the disclosure relates to an objective evaluation combined with subjective evaluation method for protection effect of a protector composition to be applied on keratin material of a user.
  • method 200 comprises blocks 201, 202, 203, 204, 205, 206 and 207.
  • Blocks 201, 202, 203, 204, 205 are the same as blocks 101, 102, 103, 104, 105 shown in Fig. 1. Thus, blocks 201, 202, 203, 204, 205 are not described in detailed.
  • the protector composition is applied on the first test area (see block 201) and then the inducer agent is applied on the applied protector composition (see block 202) ; by blocks 203, 204, a first parameter value and a second parameter value are obtained respectively.
  • the first parameter value can be a redness value of keratin material for the first test area and the second parameter value can be transepidermal water loss values of the keratin material for the second test area.
  • a first self-perceived sensation information for the first test area is obtained from the user after the block 203 of removing.
  • the first self-perceived sensation information for the first test area is obtained from the user in 5mins to 30mins, preferably in 5mins-15mins after the block 203 of removing.
  • the first self-perceived sensation information is information related to itching, burning and stinging. Order of performing blocks 204, 205, 206 can be exchanged.
  • protection effect is evaluated based on the first parameter value, the second parameter value and the first self-perceived sensation information. Compared with classical self-assessment to evaluate protection efficacy on keratin material from chemical treatment, the disclosure can achieve an objective evaluation combined with subjective evaluation method.
  • inducer agent can be any chemical composition may cause irritation or discomfort to keratin material.
  • protection effect of a protector composition to be applied on keratin material of a user we can also consider some subjective factors. For example, after the third step, we can obtain the first self-perceived sensation information related to itching, burning and stinging from the user. Finally, protection effect is evaluated based on the redness values, transepidermal water loss values and the first self-perceived sensation information. By so, an objective evaluation combined with subjective evaluation method for protector composition can be achieved.
  • FIG. 3 shows a flowchart of a method 300 of evaluating protection effect of a protector composition to be applied on keratin material of a user in accordance with a third embodiment of a first aspect of the present disclosure.
  • a second test area is selected as a reference area.
  • left branch in method 300 comprises blocks 301, 302, 303, 304, 305, which are the same as blocks 101, 102, 103, 104, 105 shown in Fig. 1.
  • blocks 301, 302, 303, 304, 305 are not described in detailed. Similar to those described in Fig.
  • the first test area is imaged to obtain a first parameter value which can be redness value; at block 305, the first test area is measured to obtain a second parameter value which can be transepidermal water loss value of the keratin material. Order of performing blocks 304, 305 can be exchanged.
  • Right branch in method 300 comprises blocks 301 ⁇ , 303 ⁇ , 304 ⁇ , 305 ⁇ . Note that in order to keep reference numbers in other figures consistent, reference number 302 ⁇ is not used.
  • the inducer agent which will cause redness and/or discomfort for keratin material of the user is directly applied on the second test area of the user. After a predefined time period, the applied inducer agent is removed from the second test area shown at block 303 ⁇ . In an example, the predefined time period can be from 5mins to 30mins, preferably from 5mins-15mins.
  • the second test area is imaged by an imaging device to obtain a third parameter value.
  • such imaging device can be a camera, a mobile phone with imaging capability, a notebook with imaging capability and so on.
  • the third parameter value can be a redness value of keratin material for the second test area.
  • the second test area is measured to obtain a fourth parameter value.
  • block 305 ⁇ can be performed by a device for testing transepidermal water loss values of the keratin material and the fourth parameter value can be transepidermal water loss value of the keratin material. Order of performing blocks 304 ⁇ , 305 ⁇ can be exchanged.
  • the first parameter value and the third parameter value correspond to situations with the protector composition and without the protector composition respectively and are related to redness values for the keratin material.
  • the second parameter value and the fourth parameter value correspond to situations with the protector composition and without the protector composition respectively and are related to transepidermal water Loss values of the keratin material.
  • protection effect is evaluated by comparing the first parameter value and the third parameter value and comparing the second parameter value and the fourth parameter value.
  • change difference for redness value between the first parameter value and the third parameter value and change difference for transepidermal water loss values between the second parameter value and the fourth parameter value can be obtained, which can reflect protection effect compared with situations with no protector composition in an intuition manner.
  • Fig. 4 illustrates a flowchart of a method 400 of evaluating protection effect of a protector composition to be applied on keratin material of a user in accordance with a fourth embodiment of a first aspect of the present disclosure.
  • a second test area is selected as a reference area.
  • left branch in method 400 comprises blocks 401, 402, 403, 404, 405 which are the same as blocks 201, 202, 203, 204, 205 shown in Fig. 2.
  • blocks 401, 402, 403, 404, 405 are not described in detail. Similar to those described in Fig. 2, at block 404, the first test area is imaged to obtain a first parameter value which can be redness value for the keratin material; at block 405, the first test area is measured to obtain a second parameter value which can be transepidermal water loss value of the keratin material. Order of performing blocks 404, 405 can be exchanged.
  • Right branch in method 400 comprises blocks 401 ⁇ , 403 ⁇ , 404 ⁇ , 405 ⁇ . Note that in order to keep reference numbers in other figures consistent, reference number 402 ⁇ is not used.
  • the inducer agent which will cause redness and/or discomfort for keratin material of the user is directly applied on a second test area of the user. After a predefined time period, the applied inducer agent is removed from the second test area shown at block 403 ⁇ .
  • the predefined time period can be from 5mins to 30mins, preferably from 5mins-15mins.
  • the second test area is imaged by an imaging device to obtain a third parameter value.
  • the third parameter can be redness value of keratin material.
  • such imaging device can be a camera, a mobile phone with imaging capability, a notebook with imaging capability and so on.
  • the second test area is measured to obtain a fourth parameter value.
  • block 405 ⁇ can be performed by a device for testing transepidermal water Loss of the keratin material and the fourth parameter value can be transepidermal water loss value of the keratin material.
  • a first self-perceived sensation information for the first test area is obtained from the user after the block 403 of removing.
  • a second self-perceived sensation information for the second test area is obtained from the user after block 403 ⁇ of removing. Order of performing blocks 404, 405, 406 can be exchanged.
  • the first and the second self-perceived sensation information are information related to itching, burning and stinging.
  • protection effect is evaluated based on comparing results between the first parameter value and the third parameter value; comparing results between the second parameter value and the fourth parameter value and comparing results between the first self-perceived sensation information and the second self-perceived sensation information.
  • the first parameter value and the third parameter value correspond to situations with protector composition and without protector composition respectively and are related to redness values for the keratin material.
  • the second parameter value and the fourth parameter value correspond to situations with protector composition and without protector composition respectively and are related to transepidermal water loss values of the keratin material.
  • change difference for redness value between the first parameter value and the third parameter value and change difference for transepidermal Water loss values between the second parameter value and the fourth parameter value can be obtained.
  • Such change differences combined with self-perceived sensation information can reflect protection effect compared with situations with no protector composition in an intuition manner in terms of objective signs such as redness, and subjective signs such as itching, burning and stinging.
  • inducer agent can be any chemical composition may cause irritation or discomfort to keratin material.
  • step to second step is occurred in the second test area.
  • the scraper is at a 45-degree angle with second test area. Gently spread the inducer agent and slowly extend it to all sides, and evenly distribute the inducer agent in the second test area.
  • image the first test area to obtain a plurality of first images and measure the first test area to obtain transepidermal water loss value of the keratin material. Further, image the second test area to obtain a plurality of second images and measure the second test area to obtain transepidermal water loss value of the keratin material.
  • evaluate protection effect based on comparing results of the redness values for the first test area and the second test area and comparing results of transepidermal water loss values for the first test area and the second test area.
  • protection effect of a protector composition to be applied on keratin material of a user we can consider some subjective factors. For example, after the third step, we can obtain the first and the second self-perceived sensation information related to itching, burning and stinging from the user. Finally, protection effect is evaluated based on the comparing results of redness values for the first test area and the second test area, comparing results of transepidermal water loss values for the first test area and the second test area and comparing results of the first and second self-perceived sensation information. By so, an objective evaluation combined with subjective evaluation method for protector composition can be achieved.
  • a third aspect of the disclosure we can obtain protection effect of a plurality of different protector compositions in a faster and more accuracy manner. More particularly, we can select a plurality of test areas to be applied a plurality of different protector compositions respectively and then applied the same inducer agent which will cause redness and/or discomfort for keratin material of the user on the applied different protector composition respectively. Then, steps of removing, imaging and measuring are performed on the plurality of test areas similar to the above-mentioned steps. Thus, we will obtain a plurality set of parameter values for each of the plurality of test areas. In an example, such parameter values can be redness values and transepidermal water loss values and can be displayed in a histogram form on a display of a computing device.
  • each of the plurality of different protector compositions is applied on each of a first plurality of test areas in ear back of the user and on each of a second plurality of test areas in forearm of the user respectively; inducer agents which will cause redness and/or discomfort for keratin material of the user is applied above each of the applied different protector compositions respectively; the applied different protector compositions and the applied inducer agents is removed from the first plurality of test areas and from the second plurality of test areas respectively; the first plurality of test areas is imaged by an imaging device to obtain a first plurality of parameter values; the second plurality of test areas by a device for testing transepidermal water loss value of the keratin material is measured to obtain a second plurality of parameter values; and protection effect is evaluated based on the first plurality of parameter values and the second plurality of parameter values.
  • the first plurality of parameter values are redness values of the keratin material in ear back; the second plurality of parameter values are transepid
  • protection effect of the plurality of protector compositions to be applied on keratin material of a user we can consider some subjective factors.
  • protection effect is evaluated based on the comparing results of redness values for the plurality of test areas, comparing results of transepidermal water loss values for the plurality of test areas and comparing results of the plurality of sensation information.
  • a first plurality of self-perceived sensation information for the first plurality of test areas from the user is obtained after the step of removing the applied different protector compositions and the applied inducer agents from the first plurality of test areas. Protection effect for a plurality of different protector products is evaluated based on the first plurality of parameter values, the second plurality of parameter values and the first plurality of self-perceived sensation information.
  • the first plurality of parameter values are redness values of the keratin material in ear back; the second plurality of parameter values are transepidermal water loss values of the keratin material in forearm.
  • the first plurality of self-perceived sensation information are information related to itching, burning and stinging.
  • a new test area as a test area without applying any protector compositions.
  • Such new test area can be applied the inducer agent directly.
  • steps of removing, imaging and measuring are performed on the new test area similar to the above-mentioned steps.
  • redness values and transepidermal water loss value for the new test area can be obtained, which can also be displayed in a histogram form on a display.
  • the inducer agents are applied on a third test area in ear back of the user and on a fourth test area in forearm of the user directly; the applied inducer agents are removed from the third test area and the fourth test area after a predefined time period such as 5mins-15mins; the third test area is imaged by the imaging device to obtain a third parameter value; the fourth test area is measured by the device for testing transepidermal water loss of the keratin material to obtain a fourth parameter value; protection effect is evaluated by comparing the first plurality of parameter values and the third parameter values and comparing the second plurality of parameter values and the fourth parameter value.
  • the first plurality of parameter values and the third parameter value are redness values of the keratin material in ear back; the second plurality of parameter values and the fourth parameter value are transepidermal water loss values of the keratin material in forearm.
  • a new test area as a test area without applying any protector compositions.
  • We can obtain a self-perceived sensation information related to itching, burning and stinging from the user for the new test area which can be displayed in percentage form, in a histogram form or in other form on a display.
  • steps of removing, imaging and measuring are performed on the new test area similar to the above-mentioned steps. Further, redness values and transepidermal water loss value for the new test area can be obtained, which can also be displayed in a histogram form on a display.
  • a third self-perceived sensation information for the third test area is also obtained after the step of removing the applied inducer agent from the third test area; wherein the evaluating step also comprising evaluating protection effect by comparing the first plurality of parameter values and the third parameter values; comparing the second plurality of parameter values and the fourth parameter value; and comparing the first plurality of self-perceived sensation information and the third self-perceived sensation information.
  • the first plurality of parameter values and the third parameter values are redness values of the keratin material in ear back; the second plurality of parameter values and the fourth parameter value are transepidermal water loss values of the keratin material in forearm.
  • the first plurality of self-perceived sensation information and the third self-perceived sensation information are information related to itching, burning and stinging.
  • the amounts of protector composition and the inducer agent to be applied and size of test area are only example and are not limited to the above-mentioned values.
  • the protector composition is applied in about 0.01g-0.1g/cm 2 and the inducer agent is applied in about 0.01g-1g/cm 2 .
  • Fig. 5 illustrates a block diagram of a computing device 500 of evaluating protection effect of a protector composition to be applied on keratin material of a user in accordance with a second aspect of the present disclosure.
  • the computing device 500 comprises an imaging device 501, a measurement unit 502 and processor 503.
  • the imaging device 501 includes computational circuitry configured to image a first test area of keratin material of the user to obtain a plurality of first images.
  • the measurement unit 502 includes computational circuitry configured to measure the first test area to obtain a second parameter value.
  • the processor 503 includes computational circuitry configured to obtain a first parameter value for the first test area and evaluate protection effect based on the first parameter value and the second parameter value.
  • a protector composition is applied on the first test area of keratin material of the user.
  • the protector composition can be a protection product for keratin material of the user.
  • the test area can be one of ear back, forearm and any area of the user body.
  • an inducer agent which will cause redness and/or discomfort for keratin material of the user is applied above the applied protector composition.
  • the inducer agent can be those with high pH ingredient and risk to induce keratin material redness and discomfort.
  • the applied protector composition and the applied inducer agent are removed from the first test area within a predefined time period after applying the inducer agent.
  • the predefined time period can be from 5mins to 30mins, preferably from 5mins-15mins.
  • imaging device can be a mobile phone with imaging capability, a notebook with imaging capability and so on.
  • the measurement unit can be a device for testing transepidermal water loss value of the keratin material and the second parameter value can be transepidermal water loss value of the keratin material. More particularly, the images are processed to obtain redness value of keratin material.
  • protection effect such as redness and discomfort of protector composition for keratin material can be obtained in a fast and objective manner.
  • the disclosure relates to an objective evaluation combined with subjective evaluation method for protection effect of a protector composition to be applied on keratin material of a user.
  • the processor 503 includes computational circuitry configured to also receive a first self-perceived sensation information for the first test area from the user after the applied composition and the applied inducer agent are removed from the first test area; and evaluate protection effect based on the first parameter value, the second parameter value and the first self-perceived sensation information.
  • the first parameter value is related to redness value and the second parameter value is related to transepidermal water loss value.
  • the first self-perceived sensation information is information related to itching, burning and stinging.
  • a second test area is selected as a reference area and the agent which will cause redness and/or discomfort for keratin material of the user is directly applied on the second test area of the user.
  • the applied inducer agent is removed from the second test area.
  • the predefined time period can be from 5mins to 30mins, preferably from 5mins-15mins.
  • the second test area is imaged by an imaging device 501 to obtain a plurality of first images.
  • the processor 502 processes the images for the second test area to obtain a third parameter value.
  • such imaging device 501 can be a camera, a mobile phone with imaging capability, a notebook with imaging capability and so on.
  • the second test area is measured to obtain a fourth parameter value by a measurement unit 502 such as a device for testing transepidermal water loss value of the keratin material and the fourth parameter value can be transepidermal water loss value of the keratin material.
  • a measurement unit 502 such as a device for testing transepidermal water loss value of the keratin material
  • the fourth parameter value can be transepidermal water loss value of the keratin material.
  • the first parameter value and the third parameter value correspond to situations with protector composition and without protector composition respectively and are related to redness values.
  • the second parameter value and the fourth parameter value correspond to situations with protector composition and without protector composition respectively and are related to transepidermal water loss values of the keratin material.
  • the processor 503 is configured to evaluate protection effect by comparing the first parameter value and the third parameter value and comparing the second parameter value and the fourth parameter value.
  • change difference for redness value between the first parameter value and the third parameter value and change difference for transepidermal water loss values between the second parameter value and the fourth parameter value can be obtained and can be displayed in a histogram form on a display of the computing device, which can reflect protection effect compared with situations with no protector composition in an intuition manner.
  • a protector composition to be applied on keratin material of a user is proposed.
  • a second test area is selected as a reference area.
  • the inducer agent which will cause redness and/or discomfort for keratin material of the user is directly applied on the second test area of the user. After a predefined time period, the applied inducer agent is removed from the second test area.
  • the predefined time period can be from 5mins to 30mins, preferably from 5mins-15mins.
  • the second test area is imaged by an imaging device 501 to obtain a plurality of second images for the second test area.
  • the processor 503 processes the plurality of second images to obtain a third parameter value.
  • the second test area is measured to obtain a fourth parameter value by a measurement unit 502 such as a device for testing transepidermal water loss value of the keratin material and the fourth parameter value can be transepidermal water loss value of the keratin material.
  • the first self-perceived sensation information for the first test area is obtained from the user after removing the applied protector composition and applied inducer agent from the first test area and the second self-perceived sensation information for the second test area is obtained from the user after removing the applied inducer agent from the second test area.
  • the first and the second self-perceived sensation information are information related to itching, burning and stinging.
  • the first parameter value and the third parameter value correspond to situations with protector composition and without protector composition respectively and are related to redness values for keratin material.
  • the second parameter value and the fourth parameter value correspond to situations with protector composition and without protector composition respectively and are related to transepidermal water loss values of the keratin material.
  • the processor 503 is also configured to evaluate protection effect based on comparing results between the first parameter value and the third parameter value; comparing results between the second parameter value and the fourth parameter value and comparing results between the first self-perceived sensation information and the second self-perceived sensation information.
  • change difference for redness value between the first parameter value and the third parameter value and change difference for transepidermal water loss values between the second parameter value and the fourth parameter value can be obtained.
  • Such change differences combined with self-perceived sensation information can reflect protection effect compared with situations with no protector composition in an intuition manner in terms of objective signs such as redness and subjective signs such as itching, burning and stinging.
  • Computing device 500 can be, for example, a server of a service provider, a device associated with a client (e.g, a client device) , a system on a chip, and/or any other suitable computing device or computing system.
  • computing device 500 can take a variety of different configurations.
  • computing device 500 can be implemented as a computer-like device including a personal computer, desktop computer, multi-screen computer, laptop computer, netbook, and the like.
  • Computing device 500 can also be implemented as a mobile device-like device that includes mobile devices such as mobile phones, portable music players, portable gaming devices, tablet computers, multi-screen computers, and the like.
  • Computing device 500 can also be implemented as a television-like device that includes a device having or connected to a generally larger screen in a casual viewing environment. These devices include televisions, set-top boxes, game consoles, and the like.
  • computational circuitry includes, among other things, one or more computing devices such as a processor (e.g., a microprocessor, a quantum processor, qubit processor, etc. ) , a central processing unit (CPU) , a digital signal processor (DSP) , an application-specific integrated circuit (ASIC) , a field programmable gate array (FPGA) , and the like, or any combinations thereof, and can include discrete digital or analog circuit elements or electronics, or combinations thereof.
  • computational circuitry includes one or more ASICs having a plurality of predefined logic components.
  • computational circuitry includes one or more FPGAs, each having a plurality of programmable logic components.
  • computation circuitry includes one or more electric circuits, printed circuits, flexible circuits, electrical conductors, electrodes, cavity resonators, conducting traces, ceramic patterned electrodes, electro-mechanical components, transducers, and the like.
  • computational circuitry includes one or more components operably coupled (e.g., communicatively, electromagnetically, magnetically, ultrasonically, optically, inductively, electrically, capacitively coupled, wirelessly coupled, and the like) to each other.
  • circuitry includes one or more remotely located components.
  • remotely located components are operably coupled, for example, via wireless communication.
  • remotely located components are operably coupled, for example, via one or more communication modules, receivers, transmitters, transceivers, and the like.
  • computation circuitry includes memory that, for example, stores instructions or information.
  • memory includes volatile memory (e.g., Random Access Memory (RAM) , Dynamic Random Access Memory (DRAM) , and the like) , non-volatile memory (e.g., Read-Only Memory (ROM) , Electrically Erasable Programmable Read-Only Memory (EEPROM) , Compact Disc Read-Only Memory (CD-ROM) , and the like) , persistent memory, and the like.
  • RAM Random Access Memory
  • DRAM Dynamic Random Access Memory
  • EEPROM Electrically Erasable Programmable Read-Only Memory
  • CD-ROM Compact Disc Read-Only Memory
  • EPROM Erasable Programmable Read-Only Memory
  • memory is coupled to, for example, one or more computing devices by one or more instructions, information, or power buses.
  • computational circuitry includes one or more databases stored in memory.
  • computational circuitry includes one or more look-up tables stored in memory.
  • computational circuitry includes one or more computer-readable media drives, interface sockets, Universal Serial Bus (USB) ports, memory card slots, and the like, and one or more input/output components such as, for example, a graphical user interface, a display, a keyboard, a keypad, a trackball, a joystick, a touch-screen, a mouse, a switch, a dial, and the like, and any other peripheral device.
  • USB Universal Serial Bus
  • computational circuitry includes one or more user input/output components that are operably coupled to at least one computing device configured to control (electrical, electromechanical, software-implemented, firmware-implemented, or other control, or combinations thereof) at least one parameter associated with, for example, determining one or more tissue thermal properties responsive to detected shifts in turn-on voltage.
  • computational circuitry includes electrical circuitry forming a general purpose computing device configured by a computer program (e.g., a general purpose computer configured by a computer program which at least partially carries out processes and/or devices described herein, or a microprocessor configured by a computer program which at least partially carries out processes and/or devices described herein) , electrical circuitry forming a memory device (e.g., forms of memory (e.g., random access, flash, read only, etc. ) ) , electrical circuitry forming a communications device (e.g., a modem, communications switch, optical-electrical equipment, etc. ) , and/or any non-electrical analog thereto, such as optical or other analogs.
  • a computer program e.g., a general purpose computer configured by a computer program which at least partially carries out processes and/or devices described herein, or a microprocessor configured by a computer program which at least partially carries out processes and/or devices described herein
  • An embodiment of the disclosure may be an article of manufacture in which a non-transitory machine-readable medium (such as microelectronic memory) has stored thereon instructions (e.g., computer code) which program one or more data processing components (generically referred to here as a “processor” ) to perform the operations described above.
  • a non-transitory machine-readable medium such as microelectronic memory
  • instructions e.g., computer code
  • data processing components program one or more data processing components (generically referred to here as a “processor” ) to perform the operations described above.
  • some of these operations might be performed by specific hardware components that contain hardwired logic (e.g., dedicated digital filter blocks and state machines) .
  • Those operations might alternatively be performed by any combination of programmed data processing components and fixed hardwired circuit components.

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Abstract

There is provided a method and a computing device for evaluating protection effect of a protector composition to be applied on keratin material of a user, and the method comprises the steps of: applying the protector composition on a first test area of keratin material of the user; applying an inducer agent which will cause redness and/or discomfort for keratin material of the user above the applied protector composition; removing the applied protector composition and the applied inducer agent from the first parameter value;measuring the first test area by a device for testing transepidermal water loss of the keratin material to obtain a second parameter value; and evaluating protection effect based on the first parameter value and the second parameter value.

Description

A METHOD AND A COMPUTING DEVICE FOR EVALUATING PROTECTION EFFECT OF A PROTECTOR COMPOSITION TO BE APPLIED ON KERATIN MATERAL OF A USER TECHNICAL FIELD
The disclosure relates to the field of cosmetics. More specifically, the disclosure relates to a method and a computing device for evaluating protection effect of a protector composition to be applied on keratin material of a user.
BACKGROUND
Nowadays, people are increasingly pursuing external beauty. By dressing, keratin material makeup and various kinds of hair care, the needs of beauty can be achieved. Typically, people apply some protector compositions on keratin material before applying some makeup products, hair care products and so on. In prior art, there are no fast and efficient methods for evaluating protection effect of protector compositions to be applied on keratin materials.
Thus, there is a need for a method for evaluating protection effect of a protector composition to be applied on keratin material of a user more particularly in terms of redness values and discomfort for keratin material in a fast and more efficient manner.
SUMMARY
The summary is provided to introduce a selection of concepts in a simplified form that are further described below in detailed description. This summary is not intended to identify key features or essential features of the claimed subject matter, nor is it intended to be used to limit the scope of the claimed subject matter.
Various aspects and features of the disclosure are described in further detail below.
According to a first aspect of the disclosure, there is provided a  method for evaluating protection effect of a protector composition to be applied on keratin material of a user, the method comprises applying the protector composition on a first test area of keratin material of the user; applying an inducer agent which will cause redness and/or discomfort for keratin material of the user above the applied protector composition; removing the applied protector composition and the applied inducer agent from the first test area; imaging the first test area by an imaging device to obtain a first parameter value;
measuring the first test area by a device for testing transepidermal water loss of the keratin material to obtain a second parameter value; and evaluating protection effect based on the first parameter value and the second parameter value.
In an embodiment of the first aspect of the disclosure, the method also comprises obtaining a first self-perceived sensation information for the first test area from the user after the step of removing the applied protector composition and the applied inducer agent from the first test area; and evaluating protection effect based on the first parameter value, the second parameter value and the first self-perceived sensation information.
In another embodiment of the first aspect of the disclosure, the method also comprises applying the inducer agent on a second test area of the user directly; removing the applied inducer agent from the second test area; imaging the second test area by the imaging device to obtain a third parameter value; measuring the second test area by the device for testing transepidermal water loss of the keratin material to obtain a fourth parameter value; and evaluating protection effect by comparing the first parameter value and the third parameter value and comparing the second parameter value and the fourth parameter value.
In yet another embodiment of the first aspect of the disclosure, the method also comprises obtaining a first self-perceived sensation information for the first test area after the step of removing the applied protector composition and the applied inducer agent from the first test area; obtaining a second self-perceived sensation information for the second test  area from said user after the step of removing the applied inducer agent from the second test area; wherein the evaluating step also comprises evaluating protection effect based on comparing result between the first parameter value and the third parameter value, comparing result between the second parameter value and the fourth parameter value and comparing result between the first self-perceived sensation information and the second self-perceived sensation information.
According to a second aspect of the disclosure, there is provided a computing device for evaluating protection effect of a protector composition to be applied on keratin material of a user, comprises an imaging device including computational circuitry configured to image a first test area of keratin material of the user to obtain a plurality of first images; a measurement unit including computational circuitry configured to measure the first test area to obtain a second parameter value; and a processor including computational circuitry configured to process the plurality of first images for the first test area to obtain a first parameter value and evaluate protection effect based on the first parameter value and the second parameter value; wherein before imaging the first test area, the first test area is applied a protector composition; then is applied an inducer agent which will cause redness and/or discomfort for keratin material of the user above the applied protector composition; finally the applied protector composition and the applied inducer agent are removed from the first test area.
In another embodiment of the second aspect of the disclosure, the processor includes computational circuitry configured to also receive a first self-perceived sensation information for the first test area from the user after the applied protector composition and the applied inducer agent are removed from the first test area; and evaluate protection effect based on the first parameter value, the second parameter value and the first self-perceived sensation information.
In yet another embodiment of the second aspect of the disclosure, the imaging device includes computational circuitry configured to also image a  second test area to obtain a plurality of second images; the measurement unit includes computational circuitry configured to measure the second test area to obtain a fourth parameter value; and the processor includes computational circuitry configured to process the plurality of second images for the second test area to obtain a third parameter value and to evaluate protection effect by comparing the first parameter value and the third parameter value and comparing the second parameter value and the fourth parameter value; before imaging the second test area, the second test area is applied the inducer agent directly; then the applied inducer agent is removed from the second test area.
In yet another embodiment of the second aspect of the disclosure, the processor includes computational circuitry configured to receive a first self-perceived sensation information for the first test area from the user after the applied protector composition and the applied inducer agent are removed from the first test area and also receive a second self-perceived sensation information for the second test area from said user after the applied inducer agent is removed from the second test area; and evaluate protection effect based on comparing results between the first parameter value and the third parameter value, comparing results between the second parameter value and the fourth parameter value; and comparing results between the first self-perceived sensation information and the second self-perceived sensation information.
In an example of the disclosure, the step of imaging is performed by an imager device and the step of measuring is performed by a device for testing transepidermal water loss of the keratin material.
In an example of the disclosure, the first test area and the second test area can be one of ear back, forearm and any area of the keratin material. In an example of the disclosure, the first parameter value and the third parameter value are redness values of the keratin material; the second parameter value and the fourth parameter value are transepidermal water loss values of the keratin material and the first and the second self-perceived sensation information are information related to itching,  burning and stinging. In an example, the step of removing the applied protector composition and the applied inducer agent from the first test area is performed in about 5-15mins after the steps of applying an inducer agent which will cause redness and/or discomfort for keratin material of the user above the applied protector composition. In an example, the step of removing the applied inducer agent from the second test area is performed in about 5-15mins after the steps of applying the inducer agent on a second test area directly. In a preferred example, the protector composition is applied in about 0.01g-0.1g/cm 2 and the inducer agent is applied in about 0.1g-1g/cm 2.
According to a third aspect of the disclosure, there is provided a computer readable medium having stored thereon instructions that when executed cause a computing device to perform the method according to the first aspect of the disclosure.
According to a fourth aspect of the disclosure, there is provided a method for evaluating protection effect of a plurality of different protector compositions to be applied on keratin material of a user, the method comprising the steps of: applying each of the plurality of different protector compositions on each of a first plurality of test areas in ear back of the user and on each of a second plurality of test areas in forearm of the user respectively; applying inducer agents which will cause redness and/or discomfort for keratin material of the user above each of the applied different protector compositions respectively; removing the applied different protector compositions and the applied inducer agents from the first plurality of test areas and from the second plurality of test areas respectively; imaging the first plurality of test areas by an imaging device to obtain a first plurality of parameter values; measuring the second plurality of test areas by a device for testing transepidermal water loss value of the keratin material to obtain a second plurality of parameter values; and evaluating protection effect based on the first plurality of parameter values and the second plurality of parameter values.
According to an embodiment in a fourth aspect of the disclosure, the  method also comprises the steps of obtaining a first plurality of self-perceived sensation information for the first plurality of test areas from the user after the step of removing the applied different protector compositions and the applied inducer agents from the first plurality of test areas; and evaluating protection effect based on the first plurality of parameter values, the second plurality of parameter values and the first plurality of self-perceived sensation information.
According to another embodiment in a fourth aspect of the disclosure, the method also comprises the steps of applying the inducer agents on a third test area in ear back of the user and on a fourth test area in forearm of the user directly; removing the applied inducer agents from the third test area and the fourth test area; imaging the third test area by the imaging device to obtain a third parameter value; measuring the fourth test area by the device for testing transepidermal water loss of the keratin material to obtain a fourth parameter value; and evaluating protection effect by comparing the first plurality of parameter values and the third parameter values and comparing the second plurality of parameter values and the fourth parameter value.
According to yet another embodiment in a fourth aspect of the disclosure, the method also comprises the steps of obtaining a third self-perceived sensation information for the third test area after the step of removing the applied inducer agent from the third test area; wherein the evaluating step also comprising evaluating protection effect by comparing the first plurality of parameter values and the third parameter values; comparing the second plurality of parameter values and the fourth parameter value; and comparing the first plurality of self-perceived sensation information and the third self-perceived sensation information.
In an embodiment of a fourth aspect of the disclosure, the first plurality of parameter values and the third parameter value are redness values of the keratin material in ear back; the second plurality of parameter values and the fourth parameter value are transepidermal water loss values of the keratin material in forearm.
In an embodiment of a fourth aspect of the disclosure, the steps of removing are performed in about 5-15mins after the steps of applying the inducer agents above the applied different protector compositions on the first plurality of test areas and on the second plurality of test areas and applying the inducer agents on the third test area and on the fourth test area directly.
In an embodiment of a fourth aspect of the disclosure, the first plurality of self-perceived sensation information and the third self-perceived sensation information are information related to itching, burning and stinging.
In an embodiment of a fourth aspect of the disclosure, the different protector compositions are applied in about 0.01g-0.1g/cm 2, and the inducer agents are applied in about 0.1g-1g/cm 2.
According to the disclosure, an objective and subjective evaluation for protector composition to be applied on keratin material of the user can be achieved in a fast and more efficient manner, thus a more accurate and quantified evaluation result can be obtained.
BRIEF DESCRIPTION OF THE DRAWINGS
The above and other aspects, features, and benefits of various embodiments of the disclosure will become more fully apparent, by way of example, from the following detailed description with reference to the accompanying drawings, in which like reference numerals or letters are used to designate like or equivalent elements. The drawings are illustrated for facilitating better understanding of the embodiments of the disclosure and not necessarily drawn to scale, in which:
Fig. 1 illustrates a flowchart of a method 100 of evaluating protection effect of a protector composition to be applied on keratin material of a user in accordance with a first embodiment of a first aspect of the present disclosure;
Fig. 2 illustrates a flowchart of a method 200 of evaluating protection effect of a protector composition to be applied on keratin material of a user  in accordance with a second embodiment of a first aspect of the present disclosure;
Fig. 3 illustrates a flowchart of a method 300 of evaluating protection effect of a protector composition to be applied on keratin material of a user in accordance with a third embodiment of a first aspect of the present disclosure;
Fig. 4 illustrates a flowchart of a method 400 of evaluating protection effect of a protector composition to be applied on keratin material of a user in accordance with a fourth embodiment of a first aspect of the present disclosure;
Fig. 5 illustrates a block diagram of a computing device 500 of evaluating protection effect of a protector composition to be applied on keratin material of a user in accordance with a second aspect of the present disclosure.
DETAILED DESCRIPTION
Embodiments herein will be described in detail hereinafter with reference to the accompanying drawings, in which embodiments are shown. These embodiments herein may, however, be embodied in many different forms and should not be construed as being limited to the embodiments set forth herein. The elements of the drawings are not necessarily to scale relative to each other. Like numbers refer to like elements throughout.
The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting. As used herein, the singular forms "a" , "an" and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise. It will be further understood that the terms "comprises" "comprising, " "includes" and/or "including" when used herein, specify the presence of stated features, integers, steps, operations, elements, and/or components, but do not preclude the presence or addition of one or more other features, integers, steps, operations, elements, components, and/or groups thereof.
Unless otherwise defined, all terms (including technical and scientific  terms) used herein have the same meanings as commonly understood. It will be further understood that a term used herein should be interpreted as having a meaning consistent with its meaning in the context of this specification and the relevant art and will not be interpreted in an idealized or overly formal sense unless expressly so defined herein.
The present technology is described below with reference to block diagrams and/or flowchart illustrations of methods, apparatus (systems) and/or computer program products according to the present embodiments. It is understood that blocks of the block diagrams and/or flowchart illustrations, and combinations of blocks in the block diagrams and/or flowchart illustrations, may be implemented by computer program instructions. These computer program instructions may be provided to a processor, controller or controlling unit of a general purpose computer, special purpose computer, and/or other programmable data processing apparatus to produce a machine, such that the instructions, which execute via the processor of the computer and/or other programmable data processing apparatus, create means for implementing the functions/acts specified in the block diagrams and/or flowchart block or blocks.
Accordingly, the present technology may be embodied in hardware and/or in software (including firmware, resident software, micro-code, etc. ) . Furthermore, the present technology may take the form of a computer program product on a computer-usable or computer-readable storage medium having computer-usable or computer-readable program code embodied in the medium for use by or in connection with an instruction execution system. In the context of this document, a computer-usable or computer-readable medium may be any medium that may contain, store, communicate, propagate, or transport the program for use by or in connection with the instruction execution system, apparatus, or device.
Embodiments herein will be described below with reference to the drawings.
The inventive concept is to evaluate protection effect of a protector composition to be applied on keratin material of a user more particularly in  terms of redness values and discomfort for keratin material.
Fig. 1 illustrates a flowchart of a method 100 of evaluating protection effect of a protector composition to be applied on keratin material of a user in accordance with a first embodiment of a first aspect of the present disclosure.
Before method 100, some actions should be prepared. The user is not allowed to use any cosmetics (including routine skin care products) on back ear 24 hours before the test and is not allowed to take sauna or bath. Before testing, the user should know written informed consent and complete inclusion/non-inclusion criteria (primary eligibility) and medical history. When testing, the user should clean back ear test area with water and pat dry with paper towel; wait in a constant temperature and humidity environment for 30 minutes.
The method 100 begins. At block 101, a protector composition is applied on a first test area of keratin material of the user. In the context of the disclosure, the protector composition can be a protection product for keratin material of the user. In an example, the test area can be one of ear back, forearm and any area of the user body. In an example, the protector composition is applied in about 0.01g-0.1g/cm 2. At block 102, an inducer agent which will cause redness and/or discomfort for keratin material of the user is applied above the applied protector composition. The inducer agent can be those with high pH ingredient and risk to induce keratin material redness, and discomfort. In an example, the inducer agent is applied in about 0.1g-lg/cm 2. At block 103, the applied protector composition and the applied inducer agent is removed from the first test area. The block 103 is performed in a predefined time period after the block 102. In an example, the predefined time period can be from 5mins to 30mins, preferably from 5mins-15mins. At block 104, the first test area is imaged by an imaging device to obtain a first parameter value. More particularly, in order to obtain more accurate result, the first test area is imaged by the imaging device more times to obtain a plurality of first images and then the plurality of first images are processed to obtain  redness value for keratin material. In an example, such imaging device can be a camera, a mobile phone with imaging capability, a notebook with imaging capability and so on. At block 105, the first test area is measured to obtain a second parameter value. In an example, block 105 can be performed by a device for testing transepidermal water loss of the keratin material and the second parameter value can be transepidermal water loss values of the keratin material. Order of performing  blocks  104, 105 can be exchanged. At block 106, protection effect is evaluated based on the first parameter value and the second parameter value. By method 100, protection effect such as in terms of redness and discomfort of protector composition for keratin material can be obtained in a fast and an objective manner.
Fig. 2 illustrates a flowchart of a method 200 of evaluating protection effect of a protector composition to be applied on keratin material of a user in accordance with a second embodiment of a first aspect of the present disclosure.
In order to evaluate protection effect of a protector composition to be applied on keratin material of a user better, the disclosure relates to an objective evaluation combined with subjective evaluation method for protection effect of a protector composition to be applied on keratin material of a user.
As shown in Fig. 2, method 200 comprises  blocks  201, 202, 203, 204, 205, 206 and 207.  Blocks  201, 202, 203, 204, 205 are the same as  blocks  101, 102, 103, 104, 105 shown in Fig. 1. Thus, blocks 201, 202, 203, 204, 205 are not described in detailed. As shown in Fig. 2, the protector composition is applied on the first test area (see block 201) and then the inducer agent is applied on the applied protector composition (see block 202) ; by  blocks  203, 204, a first parameter value and a second parameter value are obtained respectively. In an example, the first parameter value can be a redness value of keratin material for the first test area and the second parameter value can be transepidermal water loss values of the keratin material for the second test area.
At block 206, a first self-perceived sensation information for the first test area is obtained from the user after the block 203 of removing. Preferably, the first self-perceived sensation information for the first test area is obtained from the user in 5mins to 30mins, preferably in 5mins-15mins after the block 203 of removing. In an example, the first self-perceived sensation information is information related to itching, burning and stinging. Order of performing  blocks  204, 205, 206 can be exchanged. At block 207, protection effect is evaluated based on the first parameter value, the second parameter value and the first self-perceived sensation information. Compared with classical self-assessment to evaluate protection efficacy on keratin material from chemical treatment, the disclosure can achieve an objective evaluation combined with subjective evaluation method.
In order to better understand the technical solutions of  methods  100, 200, an embodiment will be given. In such an embodiment, we can take an area in ear back as the first test area and take some kind of scalp protector as protector composition to be used during the test. Before test, the first test area must be kept dry. Then, some steps are occurred as follows:
First, apply 0.08g scalp protector on one side of ear back, place the scalp protector in the center of the test area 2cm x 2cm with a scraper, and the scraper is at a 45-degree angle with the first test area. Gently spread the protector and slowly extend it to all sides, and evenly distribute the scalp protector in the first test area.
Second, apply 0.5g inducer agent on the 2cmx2cm for the first test area on ear back. Place the inducer agent above the scalp protector with a scraper, and the scraper is at a 45-degree angle with first test area. Gently spread the inducer agent and slowly extend it to all sides, and evenly distribute the inducer agent in the first test area. The inducer agent can be any chemical composition may cause irritation or discomfort to keratin material.
Third, remove the above applied scalp protector and the inducer agent respectively from the first test area in 5mins to 30mins, preferably in 5mins-15mins after the first step and the second step;
Fourth, image the first test area to obtain a plurality of first images and measure the first test area to obtain transepidermal water loss values of the keratin material;
Fifth, process the plurality of first images by a processor to obtain redness values of the keratin material;
Finally, evaluate protection effect based on the redness values and transepidermal water loss values.
Further, we can observe the redness values and transepidermal water loss values on a display, thus the user can obtain protection effect in a fast and more accurate manner.
In order to evaluate protection effect of a protector composition to be applied on keratin material of a user better, in an example, we can also consider some subjective factors. For example, after the third step, we can obtain the first self-perceived sensation information related to itching, burning and stinging from the user. Finally, protection effect is evaluated based on the redness values, transepidermal water loss values and the first self-perceived sensation information. By so, an objective evaluation combined with subjective evaluation method for protector composition can be achieved.
Of course, we can also take an area of forearm as the first test area and the above steps are performed.
In order to better obtain protection effect compared with situations with no protector composition, Fig. 3 shows a flowchart of a method 300 of evaluating protection effect of a protector composition to be applied on keratin material of a user in accordance with a third embodiment of a first aspect of the present disclosure. In an embodiment of Fig. 3, a second test area is selected as a reference area. As shown in Fig. 3, left branch in method 300 comprises  blocks  301, 302, 303, 304, 305, which are the same as  blocks  101, 102, 103, 104, 105 shown in Fig. 1. Thus, blocks 301, 302, 303, 304, 305 are not described in detailed. Similar to those described in Fig. 1, at block 304, the first test area is imaged to obtain a first parameter value which can be redness value; at block 305, the first test area is  measured to obtain a second parameter value which can be transepidermal water loss value of the keratin material. Order of performing  blocks  304, 305 can be exchanged.
Right branch in method 300 comprises blocks 301`, 303`, 304`, 305`. Note that in order to keep reference numbers in other figures consistent, reference number 302` is not used. At block 301`, the inducer agent which will cause redness and/or discomfort for keratin material of the user is directly applied on the second test area of the user. After a predefined time period, the applied inducer agent is removed from the second test area shown at block 303`. In an example, the predefined time period can be from 5mins to 30mins, preferably from 5mins-15mins. At block 304`, the second test area is imaged by an imaging device to obtain a third parameter value. In an example, such imaging device can be a camera, a mobile phone with imaging capability, a notebook with imaging capability and so on.. In an example, the third parameter value can be a redness value of keratin material for the second test area. At block 305`, the second test area is measured to obtain a fourth parameter value. In an example, block 305`can be performed by a device for testing transepidermal water loss values of the keratin material and the fourth parameter value can be transepidermal water loss value of the keratin material. Order of performing blocks 304`, 305` can be exchanged. Thus, the first parameter value and the third parameter value correspond to situations with the protector composition and without the protector composition respectively and are related to redness values for the keratin material. The second parameter value and the fourth parameter value correspond to situations with the protector composition and without the protector composition respectively and are related to transepidermal water Loss values of the keratin material. At block 306, protection effect is evaluated by comparing the first parameter value and the third parameter value and comparing the second parameter value and the fourth parameter value. In an example, change difference for redness value between the first parameter value and the third parameter value and change difference for transepidermal water  loss values between the second parameter value and the fourth parameter value can be obtained, which can reflect protection effect compared with situations with no protector composition in an intuition manner.
In order to better obtain protection effect compared with situations with no protector composition, an objective evaluation combined with subjective evaluation method for protection effect of a protector composition to be applied on keratin material of a user is proposed. Fig. 4 illustrates a flowchart of a method 400 of evaluating protection effect of a protector composition to be applied on keratin material of a user in accordance with a fourth embodiment of a first aspect of the present disclosure. In an embodiment of Fig. 4, a second test area is selected as a reference area. As shown in Fig. 4, left branch in method 400 comprises  blocks  401, 402, 403, 404, 405 which are the same as  blocks  201, 202, 203, 204, 205 shown in Fig. 2. Thus, blocks 401, 402, 403, 404, 405 are not described in detail. Similar to those described in Fig. 2, at block 404, the first test area is imaged to obtain a first parameter value which can be redness value for the keratin material; at block 405, the first test area is measured to obtain a second parameter value which can be transepidermal water loss value of the keratin material. Order of performing  blocks  404, 405 can be exchanged.
Right branch in method 400 comprises blocks 401`, 403`, 404`, 405`. Note that in order to keep reference numbers in other figures consistent, reference number 402` is not used. At block 401`, the inducer agent which will cause redness and/or discomfort for keratin material of the user is directly applied on a second test area of the user. After a predefined time period, the applied inducer agent is removed from the second test area shown at block 403`. In an example, the predefined time period can be from 5mins to 30mins, preferably from 5mins-15mins. At block 405`, the second test area is imaged by an imaging device to obtain a third parameter value. In an example, the third parameter can be redness value of keratin material. In an example, such imaging device can be a camera, a mobile phone with imaging capability, a notebook with imaging capability and so  on. At block 405`, the second test area is measured to obtain a fourth parameter value. In an example, block 405` can be performed by a device for testing transepidermal water Loss of the keratin material and the fourth parameter value can be transepidermal water loss value of the keratin material. At block 406, a first self-perceived sensation information for the first test area is obtained from the user after the block 403 of removing. At block 406`, a second self-perceived sensation information for the second test area is obtained from the user after block 403` of removing. Order of performing  blocks  404, 405, 406 can be exchanged. Order of performing blocks 404`, 405`, 406` can be exchanged. In an example, the first and the second self-perceived sensation information are information related to itching, burning and stinging. At block 407, protection effect is evaluated based on comparing results between the first parameter value and the third parameter value; comparing results between the second parameter value and the fourth parameter value and comparing results between the first self-perceived sensation information and the second self-perceived sensation information. Herein, the first parameter value and the third parameter value correspond to situations with protector composition and without protector composition respectively and are related to redness values for the keratin material. The second parameter value and the fourth parameter value correspond to situations with protector composition and without protector composition respectively and are related to transepidermal water loss values of the keratin material. In an example, change difference for redness value between the first parameter value and the third parameter value and change difference for transepidermal Water loss values between the second parameter value and the fourth parameter value can be obtained. Such change differences combined with self-perceived sensation information can reflect protection effect compared with situations with no protector composition in an intuition manner in terms of objective signs such as redness, and subjective signs such as itching, burning and stinging.
In order to better understand the technical solutions of  methods  300,  400, an embodiment will be given. In such an embodiment, we can take two areas in ear back as a first test area and a second test area; take some kind of scalp protector as protector composition to be used during the test. Before test, the first test area and the second test area must be kept dry. Then, some steps are occurred as follows:
First, apply 0.08g scalp protector on the first test area of ear back, place the scalp protector in the center of the test area 2cm x 2cm with a scraper, and the scraper is at a 45-degree angle with first test area. Gently spread the protector and slowly extend it to all sides, and evenly distribute the scalp protector in the first test area.
Second, apply 0.5g inducer agent on the 2cmx2cm for the first test area on ear back. Place the inducer agent above the scalp protector with a scraper, and the scraper is at a 45-degree angle with first test area. Gently spread the inducer agent and slowly extend it to all sides, and evenly distribute the inducer agent in the first test area. The inducer agent can be any chemical composition may cause irritation or discomfort to keratin material.
Further, similar step to second step is occurred in the second test area. Apply 0.5g inducer agent on the 2cmx2cm for the second test area on ear back. The scraper is at a 45-degree angle with second test area. Gently spread the inducer agent and slowly extend it to all sides, and evenly distribute the inducer agent in the second test area.
Third, remove the above applied scalp protector and the inducer agent respectively from the first test area in 5mins to 30mins, preferably in 5mins-15mins after the first step and the second step. Further, remove the above applied inducer agent from the second test area in 5mins to 30mins, preferably in 5mins-15mins after the similar step to the second step;
Fourth, image the first test area to obtain a plurality of first images and measure the first test area to obtain transepidermal water loss value of the keratin material. Further, image the second test area to obtain a plurality of second images and measure the second test area to obtain transepidermal water loss value of the keratin material.
Fifth, process the plurality of first images and second images by a  processor to obtain redness values of the keratin material for the first test area and the second test area respectively;
Finally, evaluate protection effect based on comparing results of the redness values for the first test area and the second test area and comparing results of transepidermal water loss values for the first test area and the second test area.
Further, we can observe the redness values and transepidermal water loss values for the first test area and the second test area in a histogram form on a display of a computing device, thus the user can obtain protection effect compared with situations with no protector composition in an intuition manner.
In order to evaluate protection effect of a protector composition to be applied on keratin material of a user better, we can consider some subjective factors. For example, after the third step, we can obtain the first and the second self-perceived sensation information related to itching, burning and stinging from the user. Finally, protection effect is evaluated based on the comparing results of redness values for the first test area and the second test area, comparing results of transepidermal water loss values for the first test area and the second test area and comparing results of the first and second self-perceived sensation information. By so, an objective evaluation combined with subjective evaluation method for protector composition can be achieved.
Of course, we can also take an area of forearm as the second test area or take two areas of forearm as the first test area and the second area and the above steps are performed.
In an embodiment of a third aspect of the disclosure, we can obtain protection effect of a plurality of different protector compositions in a faster and more accuracy manner. More particularly, we can select a plurality of test areas to be applied a plurality of different protector compositions respectively and then applied the same inducer agent which will cause redness and/or discomfort for keratin material of the user on the applied different protector composition respectively. Then, steps of  removing, imaging and measuring are performed on the plurality of test areas similar to the above-mentioned steps. Thus, we will obtain a plurality set of parameter values for each of the plurality of test areas. In an example, such parameter values can be redness values and transepidermal water loss values and can be displayed in a histogram form on a display of a computing device. Based on such parameter values displayed on the display, we can obtain protection effect for different protector compositions in a faster, more intuitive and more accurate manner. In practice, redness measurement and self-assessment are more recommended on ear back and measuring transepidermal water loss values is more recommended on forearm. In a preferred embodiment for this situation, each of the plurality of different protector compositions is applied on each of a first plurality of test areas in ear back of the user and on each of a second plurality of test areas in forearm of the user respectively; inducer agents which will cause redness and/or discomfort for keratin material of the user is applied above each of the applied different protector compositions respectively; the applied different protector compositions and the applied inducer agents is removed from the first plurality of test areas and from the second plurality of test areas respectively; the first plurality of test areas is imaged by an imaging device to obtain a first plurality of parameter values; the second plurality of test areas by a device for testing transepidermal water loss value of the keratin material is measured to obtain a second plurality of parameter values; and protection effect is evaluated based on the first plurality of parameter values and the second plurality of parameter values. In an embodiment, the first plurality of parameter values are redness values of the keratin material in ear back; the second plurality of parameter values are transepidermal water loss values of the keratin material in forearm.
In order to evaluate protection effect of the plurality of protector compositions to be applied on keratin material of a user better, we can consider some subjective factors. In an embodiment of the third aspect, we can obtain the plurality of self-perceived sensation information related to  itching, burning and stinging from the user for the plurality of test areas, which can be displayed in percentage form, in a histogram form or in other form on a display. Finally, protection effect is evaluated based on the comparing results of redness values for the plurality of test areas, comparing results of transepidermal water loss values for the plurality of test areas and comparing results of the plurality of sensation information. By so, an objective evaluation combined with subjective evaluation method for the plurality of protector compositions can be achieved. In practice, redness measurement and self-assessment are more recommended on ear back. Thus, in a preferred embodiment for this situation, a first plurality of self-perceived sensation information for the first plurality of test areas from the user is obtained after the step of removing the applied different protector compositions and the applied inducer agents from the first plurality of test areas. Protection effect for a plurality of different protector products is evaluated based on the first plurality of parameter values, the second plurality of parameter values and the first plurality of self-perceived sensation information. In an embodiment, the first plurality of parameter values are redness values of the keratin material in ear back; the second plurality of parameter values are transepidermal water loss values of the keratin material in forearm. In an embodiment, the first plurality of self-perceived sensation information are information related to itching, burning and stinging.
In order to obtain protector effect compared with no protector compositions, in an embodiment for the third aspect, we also select a new test area as a test area without applying any protector compositions. Such new test area can be applied the inducer agent directly. Then, steps of removing, imaging and measuring are performed on the new test area similar to the above-mentioned steps. Further, redness values and transepidermal water loss value for the new test area can be obtained, which can also be displayed in a histogram form on a display. Based on these parameter values with applying protector compositions and without applying protector compositions, we can obtain protection effects  compared with no protector compositions easily and quickly. In a preferred example, differences between these parameter values with applying protector compositions and without applying protector compositions can be displayed on the display. By observing such differences, protector effect can be recognized more easily. In practice, redness measurement and self-assessment are more recommended on ear back. Thus, in a preferred embodiment for this situation, the inducer agents are applied on a third test area in ear back of the user and on a fourth test area in forearm of the user directly; the applied inducer agents are removed from the third test area and the fourth test area after a predefined time period such as 5mins-15mins; the third test area is imaged by the imaging device to obtain a third parameter value; the fourth test area is measured by the device for testing transepidermal water loss of the keratin material to obtain a fourth parameter value; protection effect is evaluated by comparing the first plurality of parameter values and the third parameter values and comparing the second plurality of parameter values and the fourth parameter value. In an embodiment, the first plurality of parameter values and the third parameter value are redness values of the keratin material in ear back; the second plurality of parameter values and the fourth parameter value are transepidermal water loss values of the keratin material in forearm.
In order to obtain protector effect compared with no protector compositions, in an embodiment for the third aspect, we also select a new test area as a test area without applying any protector compositions. We can obtain a self-perceived sensation information related to itching, burning and stinging from the user for the new test area, which can be displayed in percentage form, in a histogram form or in other form on a display. Then, steps of removing, imaging and measuring are performed on the new test area similar to the above-mentioned steps. Further, redness values and transepidermal water loss value for the new test area can be obtained, which can also be displayed in a histogram form on a display. Based on these parameter values obtained with applying protector compositions and without applying protector compositions, we can obtain  protection effects compared with no protector compositions easily and quickly. In a preferred example, differences between these parameter values obtained with applying protector compositions and without applying protector compositions and comparing results between some self-perceived sensation information can be displayed on the display. By observing such differences, protector effect can be recognized more easily. In practice, redness measurement and self-assessment are more recommended on ear back. Thus, in a preferred embodiment for this situation, a third self-perceived sensation information for the third test area is also obtained after the step of removing the applied inducer agent from the third test area; wherein the evaluating step also comprising evaluating protection effect by comparing the first plurality of parameter values and the third parameter values; comparing the second plurality of parameter values and the fourth parameter value; and comparing the first plurality of self-perceived sensation information and the third self-perceived sensation information. In an embodiment, the first plurality of parameter values and the third parameter values are redness values of the keratin material in ear back; the second plurality of parameter values and the fourth parameter value are transepidermal water loss values of the keratin material in forearm. In an embodiment, the first plurality of self-perceived sensation information and the third self-perceived sensation information are information related to itching, burning and stinging.
In the context of the disclosure, the amounts of protector composition and the inducer agent to be applied and size of test area are only example and are not limited to the above-mentioned values. Preferably, the protector composition is applied in about 0.01g-0.1g/cm 2 and the inducer agent is applied in about 0.01g-1g/cm 2.
Fig. 5 illustrates a block diagram of a computing device 500 of evaluating protection effect of a protector composition to be applied on keratin material of a user in accordance with a second aspect of the present disclosure.
The computing device 500 comprises an imaging device 501, a  measurement unit 502 and processor 503. The imaging device 501 includes computational circuitry configured to image a first test area of keratin material of the user to obtain a plurality of first images. The measurement unit 502 includes computational circuitry configured to measure the first test area to obtain a second parameter value. The processor 503 includes computational circuitry configured to obtain a first parameter value for the first test area and evaluate protection effect based on the first parameter value and the second parameter value.
Before imaging the first test area, several steps are performed. First, a protector composition is applied on the first test area of keratin material of the user. In the context of the disclosure, the protector composition can be a protection product for keratin material of the user. In an example, the test area can be one of ear back, forearm and any area of the user body. Next, an inducer agent which will cause redness and/or discomfort for keratin material of the user is applied above the applied protector composition. The inducer agent can be those with high pH ingredient and risk to induce keratin material redness and discomfort. Next, the applied protector composition and the applied inducer agent are removed from the first test area within a predefined time period after applying the inducer agent. In an example, the predefined time period can be from 5mins to 30mins, preferably from 5mins-15mins. In an example, such imaging device can be a mobile phone with imaging capability, a notebook with imaging capability and so on. In an example, the measurement unit can be a device for testing transepidermal water loss value of the keratin material and the second parameter value can be transepidermal water loss value of the keratin material. More particularly, the images are processed to obtain redness value of keratin material. By such computing device, protection effect such as redness and discomfort of protector composition for keratin material can be obtained in a fast and objective manner.
In order to evaluate protection effect of a protector composition to be applied on keratin material of a user better, the disclosure relates to an objective evaluation combined with subjective evaluation method for  protection effect of a protector composition to be applied on keratin material of a user. In an example, the processor 503 includes computational circuitry configured to also receive a first self-perceived sensation information for the first test area from the user after the applied composition and the applied inducer agent are removed from the first test area; and evaluate protection effect based on the first parameter value, the second parameter value and the first self-perceived sensation information. In an example, the first parameter value is related to redness value and the second parameter value is related to transepidermal water loss value. In an example, the first self-perceived sensation information is information related to itching, burning and stinging.
In order to better obtain protection effect compared with situations with no protector composition, in an embodiment, a second test area is selected as a reference area and the agent which will cause redness and/or discomfort for keratin material of the user is directly applied on the second test area of the user. After a predefined time period, the applied inducer agent is removed from the second test area. In an example, the predefined time period can be from 5mins to 30mins, preferably from 5mins-15mins. Then, the second test area is imaged by an imaging device 501 to obtain a plurality of first images. The processor 502 processes the images for the second test area to obtain a third parameter value. In an example, such imaging device 501 can be a camera, a mobile phone with imaging capability, a notebook with imaging capability and so on. Then, the second test area is measured to obtain a fourth parameter value by a measurement unit 502 such as a device for testing transepidermal water loss value of the keratin material and the fourth parameter value can be transepidermal water loss value of the keratin material. Herein, the first parameter value and the third parameter value correspond to situations with protector composition and without protector composition respectively and are related to redness values. The second parameter value and the fourth parameter value correspond to situations with protector composition and without protector composition respectively and are related to transepidermal water  loss values of the keratin material. The processor 503 is configured to evaluate protection effect by comparing the first parameter value and the third parameter value and comparing the second parameter value and the fourth parameter value. In an example, change difference for redness value between the first parameter value and the third parameter value and change difference for transepidermal water loss values between the second parameter value and the fourth parameter value can be obtained and can be displayed in a histogram form on a display of the computing device, which can reflect protection effect compared with situations with no protector composition in an intuition manner.
In order to better obtain protection effect compared with situations with no protector composition, an objective evaluation combined with subjective evaluation method for protection effect of a protector composition to be applied on keratin material of a user is proposed. In an example, a second test area is selected as a reference area.
The inducer agent which will cause redness and/or discomfort for keratin material of the user is directly applied on the second test area of the user. After a predefined time period, the applied inducer agent is removed from the second test area. In an example, the predefined time period can be from 5mins to 30mins, preferably from 5mins-15mins. Then, the second test area is imaged by an imaging device 501 to obtain a plurality of second images for the second test area. The processor 503 processes the plurality of second images to obtain a third parameter value. The second test area is measured to obtain a fourth parameter value by a measurement unit 502 such as a device for testing transepidermal water loss value of the keratin material and the fourth parameter value can be transepidermal water loss value of the keratin material. The first self-perceived sensation information for the first test area is obtained from the user after removing the applied protector composition and applied inducer agent from the first test area and the second self-perceived sensation information for the second test area is obtained from the user after removing the applied inducer agent from the second test area. In an example, the first and the second self-perceived  sensation information are information related to itching, burning and stinging. Herein, the first parameter value and the third parameter value correspond to situations with protector composition and without protector composition respectively and are related to redness values for keratin material. The second parameter value and the fourth parameter value correspond to situations with protector composition and without protector composition respectively and are related to transepidermal water loss values of the keratin material. In an embodiment, the processor 503 is also configured to evaluate protection effect based on comparing results between the first parameter value and the third parameter value; comparing results between the second parameter value and the fourth parameter value and comparing results between the first self-perceived sensation information and the second self-perceived sensation information. In an example, change difference for redness value between the first parameter value and the third parameter value and change difference for transepidermal water loss values between the second parameter value and the fourth parameter value can be obtained. Such change differences combined with self-perceived sensation information can reflect protection effect compared with situations with no protector composition in an intuition manner in terms of objective signs such as redness and subjective signs such as itching, burning and stinging.
Computing device 500 can be, for example, a server of a service provider, a device associated with a client (e.g, a client device) , a system on a chip, and/or any other suitable computing device or computing system. In various implementations, computing device 500 can take a variety of different configurations. For example, computing device 500 can be implemented as a computer-like device including a personal computer, desktop computer, multi-screen computer, laptop computer, netbook, and the like. Computing device 500 can also be implemented as a mobile device-like device that includes mobile devices such as mobile phones, portable music players, portable gaming devices, tablet computers, multi-screen computers, and the like. Computing device 500 can also be  implemented as a television-like device that includes a device having or connected to a generally larger screen in a casual viewing environment. These devices include televisions, set-top boxes, game consoles, and the like.
In an embodiment, computational circuitry includes, among other things, one or more computing devices such as a processor (e.g., a microprocessor, a quantum processor, qubit processor, etc. ) , a central processing unit (CPU) , a digital signal processor (DSP) , an application-specific integrated circuit (ASIC) , a field programmable gate array (FPGA) , and the like, or any combinations thereof, and can include discrete digital or analog circuit elements or electronics, or combinations thereof. In an embodiment, computational circuitry includes one or more ASICs having a plurality of predefined logic components. In an embodiment, computational circuitry includes one or more FPGAs, each having a plurality of programmable logic components.
In an embodiment, computation circuitry includes one or more electric circuits, printed circuits, flexible circuits, electrical conductors, electrodes, cavity resonators, conducting traces, ceramic patterned electrodes, electro-mechanical components, transducers, and the like.
In an embodiment, computational circuitry includes one or more components operably coupled (e.g., communicatively, electromagnetically, magnetically, ultrasonically, optically, inductively, electrically, capacitively coupled, wirelessly coupled, and the like) to each other. In an embodiment, circuitry includes one or more remotely located components. In an embodiment, remotely located components are operably coupled, for example, via wireless communication. In an embodiment, remotely located components are operably coupled, for example, via one or more communication modules, receivers, transmitters, transceivers, and the like.
In an embodiment, computation circuitry includes memory that, for example, stores instructions or information. Non-limiting examples of memory include volatile memory (e.g., Random Access Memory (RAM) , Dynamic Random Access Memory (DRAM) , and the like) , non-volatile  memory (e.g., Read-Only Memory (ROM) , Electrically Erasable Programmable Read-Only Memory (EEPROM) , Compact Disc Read-Only Memory (CD-ROM) , and the like) , persistent memory, and the like. Further non-limiting examples of memory include Erasable Programmable Read-Only Memory (EPROM) , flash memory, and the like. In an embodiment, memory is coupled to, for example, one or more computing devices by one or more instructions, information, or power buses. In an embodiment, computational circuitry includes one or more databases stored in memory. In an embodiment, computational circuitry includes one or more look-up tables stored in memory.
In an embodiment, computational circuitry includes one or more computer-readable media drives, interface sockets, Universal Serial Bus (USB) ports, memory card slots, and the like, and one or more input/output components such as, for example, a graphical user interface, a display, a keyboard, a keypad, a trackball, a joystick, a touch-screen, a mouse, a switch, a dial, and the like, and any other peripheral device. In an embodiment, computational circuitry includes one or more user input/output components that are operably coupled to at least one computing device configured to control (electrical, electromechanical, software-implemented, firmware-implemented, or other control, or combinations thereof) at least one parameter associated with, for example, determining one or more tissue thermal properties responsive to detected shifts in turn-on voltage.
In an embodiment, computational circuitry includes electrical circuitry forming a general purpose computing device configured by a computer program (e.g., a general purpose computer configured by a computer program which at least partially carries out processes and/or devices described herein, or a microprocessor configured by a computer program which at least partially carries out processes and/or devices described herein) , electrical circuitry forming a memory device (e.g., forms of memory (e.g., random access, flash, read only, etc. ) ) , electrical circuitry forming a communications device (e.g., a modem, communications switch,  optical-electrical equipment, etc. ) , and/or any non-electrical analog thereto, such as optical or other analogs.
An embodiment of the disclosure may be an article of manufacture in which a non-transitory machine-readable medium (such as microelectronic memory) has stored thereon instructions (e.g., computer code) which program one or more data processing components (generically referred to here as a “processor” ) to perform the operations described above. In other embodiments, some of these operations might be performed by specific hardware components that contain hardwired logic (e.g., dedicated digital filter blocks and state machines) . Those operations might alternatively be performed by any combination of programmed data processing components and fixed hardwired circuit components.
While the embodiments have been illustrated and described herein, it will be understood by those skilled in the art that various changes and modifications may be made, and equivalents may be substituted for elements thereof without departing from the true scope of the present technology. In addition, many modifications may be made to adapt to a particular situation and the teaching herein without departing from its central scope. Therefore it is intended that the present embodiments not be limited to the particular embodiment disclosed as the best mode contemplated for carrying out the present technology, but that the present embodiments include all embodiments falling within the scope of the appended claims.

Claims (28)

  1. A method for evaluating protection effect of a protector composition to be applied on keratin material of a user, the method comprising the steps of:
    - applying the protector composition on a first test area of keratin material of the user;
    - applying an inducer agent which will cause redness and/or discomfort for keratin material of the user above the applied protector composition;
    - removing the applied protector composition and the applied inducer agent from the first test area;
    - imaging the first test area by an imaging device to obtain a first parameter value;
    - measuring the first test area by a device for testing transepidermal water loss value of the keratin material to obtain a second parameter value; and
    - evaluating protection effect based on the first parameter value and the second parameter value.
  2. The method according to claim 1, also comprising the steps of:
    - obtaining a first self-perceived sensation information for the first test area from the user after the step of removing the applied protector composition and the applied inducer agent from the first test area; and
    - evaluating protection effect based on the first parameter value, the second parameter value and the first self-perceived sensation information.
  3. The method according to claim 1, also comprising the steps of:
    - applying the inducer agent on a second test area of the user directly;
    - removing the applied inducer agent from the second test area;
    - imaging the second test area by the imaging device to obtain a third parameter value;
    - measuring the second test area by the device for testing transepidermal water loss of the keratin material to obtain a fourth  parameter value; and
    - evaluating protection effect by comparing the first parameter value and the third parameter value and comparing the second parameter value and the fourth parameter value.
  4. The method according to claim 3, also comprising the steps of:
    - obtaining a first self-perceived sensation information for the first test area after the step of removing the applied protector composition and the applied inducer agent from the first test area; and
    - obtaining a second self-perceived sensation information for the second test area from said user after the step of removing the applied inducer agent from the second test area;
    wherein the evaluating step also comprising evaluating protection effect based on comparing results between the first parameter value and the third parameter value, comparing results between the second parameter value and the fourth parameter value; and comparing result between the first self-perceived sensation information and the second self-perceived sensation information.
  5. The method according to any one of claims 1-4, wherein the steps of imaging comprising:
    - imaging the first and second test areas by the imaging device to obtain a plurality of first images and a plurality of second images; and
    - processing the plurality of first images and the plurality of second images to obtain redness values of the keratin material for the first and second test areas.
  6. The method of any one of claims 1-4, wherein the steps of measuring comprising:
    - measuring the first and second test areas by the device for testing trans epidermal water loss of the keratin material;
    - obtaining transepidermal water loss values of the keratin material for the first and second test areas; and
    - displaying the transepidermal water loss values on a display of the device.
  7. The method according to any one of claims 1 to 4, wherein the first test area and the second test area can be one of ear back, forearm and any area of the keratin material.
  8. The method according to any one of claims 1 to 4 , wherein the first parameter value and the third parameter value are redness values of the keratin material; the second parameter value and the fourth parameter value are transepidermal water loss values of the keratin material.
  9. The method according to any one of claims 1 to 4, wherein the steps of removing are performed in about 5-15mins after the steps of applying the inducer agent above the applied protector composition on the first test area and applying the inducer agent on the second test area directly.
  10. The method according to any one of claims 2 to 4, wherein the first self-perceived sensation information and the second self-perceived sensation information are information related to itching, burning and stinging.
  11. The method according to any one of claims 1 to 10, wherein the protector composition is applied in about 0.01g-0.1g/cm 2, and the inducer agent is applied in about 0.1g-1g/cm 2.
  12. A computing device for evaluating protection effect of a protector composition to be applied on keratin material of a user, comprising:
    - an imaging device including computational circuitry configured to image a first test area of keratin material of the user to obtain a plurality of first images;
    - a measurement unit including computational circuitry configured to measure the first test area to obtain a second parameter value;
    - a processor including computational circuitry configured to process the plurality of first images for the first test area to obtain a first parameter value and evaluate protection effect based on the first parameter value and the second parameter value;
    wherein before imaging the first test area, the first test area is applied  a protector composition; then is applied an inducer agent which will cause redness and/or discomfort for keratin material of the user above the applied protector composition, finally the applied protector composition and the applied inducer agent are removed from the first test area.
  13. The computing device according to claim 12, wherein the processor includes computational circuitry configured to also receive a first self-perceived sensation information for the first test area from the user after the applied protector composition and the applied inducer agent are removed from the first test area; and evaluate protection effect based on the first parameter value, the second parameter value and the first self-perceived sensation information.
  14. The computing device according to claim 12, wherein the imaging device includes computational circuitry configured to also image a second test area to obtain a plurality of second images;
    the measurement unit includes computational circuitry configured to measure the second test area to obtain a fourth parameter value; and
    the processor includes computational circuitry configured to process the plurality of second images for the second test area to obtain a third parameter value and evaluate protection effect by comparing the first parameter value and the third parameter value and comparing the second parameter value and the fourth parameter value;
    wherein before imaging the second test area, the second test area is applied the inducer agent directly; then the applied inducer agent is removed from the second test area.
  15. The computing device according to claim 14, wherein the processor includes computational circuitry configured to receive a first self-perceived sensation information for the first test area from the user after the applied protector composition and the applied inducer agent are removed from the first test area and also receive a second self-perceived sensation information for the second test area from said user after the applied inducer agent is removed from the second test area; and evaluate protection effect based on comparing results between the first parameter  value and the third parameter value, comparing results between the second parameter value and the fourth parameter value; and comparing results between the first self-perceived sensation information and the second self-perceived sensation information.
  16. The computing device according to any one of claims 12 to 15, wherein the measuring unit is a device for testing transepidermal water loss value of the keratin material.
  17. The computing device according to any one of claims 12 to 15, wherein the first test area and the second test area can be one of ear back, forearm and any area of the keratin material.
  18. The computing device according to any one of claims 12 to 15, wherein the first parameter value and the third parameter value are redness values of the keratin material; the second parameter value and the fourth parameter value are transepidermal water loss values of the keratin material.
  19. The computing device according to any one of claims 12 to 18, wherein the first self-perceived sensation information and the second self-perceived sensation information are information related to itching, burning and stinging.
  20. A computer readable medium having stored thereon instructions that when executed cause a computing device to perform the method according to one of claims 1-11.
  21. A method for evaluating protection effect of a plurality of different protector compositions to be applied on keratin material of a user, the method comprising the steps of:
    - applying each of the plurality of different protector compositions on each of a first plurality of test areas in ear back of the user and on each of a second plurality of test areas in forearm of the user respectively;
    - applying inducer agents which will cause redness and/or discomfort for keratin material of the user above each of the applied different protector compositions respectively;
    - removing the applied different protector compositions and the  applied inducer agents from the first plurality of test areas and from the second plurality of test areas respectively;
    - imaging the first plurality of test areas by an imaging device to obtain a first plurality of parameter values;
    - measuring the second plurality of test areas by a device for testing transepidermal water loss value of the keratin material to obtain a second plurality of parameter values; and
    - evaluating protection effect based on the first plurality of parameter values and the second plurality of parameter values.
  22. The method according to claim 21, also comprising the steps of:
    - obtaining a first plurality of self-perceived sensation information for the first plurality of test areas from the user after the step of removing the applied different protector compositions and the applied inducer agents from the first plurality of test areas; and
    - evaluating protection effect based on the first plurality of parameter values, the second plurality of parameter values and the first plurality of self-perceived sensation information.
  23. The method according to claim 21, also comprising the steps of:
    - applying the inducer agents on a third test area in ear back of the user and on a fourth test area in forearm of the user directly;
    - removing the applied inducer agents from the third test area and the fourth test area;
    - imaging the third test area by the imaging device to obtain a third parameter value;
    - measuring the fourth test area by the device for testing transepidermal water loss of the keratin material to obtain a fourth parameter value; and
    - evaluating protection effect by comparing the first plurality of parameter values and the third parameter values and comparing the second plurality of parameter values and the fourth parameter value.
  24. The method according to claim 23, also comprising the steps of:
    - obtaining a third self-perceived sensation information for the third  test area after the step of removing the applied inducer agent from the third test area;
    wherein the evaluating step also comprising evaluating protection effect by comparing the first plurality of parameter values and the third parameter values; comparing the second plurality of parameter values and the fourth parameter value; and comparing the first plurality of self-perceived sensation information and the third self-perceived sensation information.
  25. The method according to any one of claims 21 to 24 , wherein the first plurality of parameter values and the third parameter value are redness values of the keratin material in ear back; the second plurality of parameter values and the fourth parameter value are transepidermal water loss values of the keratin material in forearm.
  26. The method according to any one of claims 21 to 24, wherein the steps of removing are performed in about 5-15mins after the steps of applying the inducer agents above the applied different protector compositions on the first plurality of test areas and on the second plurality of test areas and applying the inducer agents on the third test area and on the fourth test area directly.
  27. The method according to any one of claims 22 to 24, wherein the first plurality of self-perceived sensation information and the third self-perceived sensation information are information related to itching, burning and stinging.
  28. The method according to any one of claims 21 to 27, wherein the different protector compositions are applied in about 0.01g-0.1g/cm 2, and the inducer agents are applied in about 0.1g-1g/cm 2.
PCT/CN2022/102230 2022-06-29 2022-06-29 A method and a computing device for evaluating protection effect of a protector composition to be applied on keratin materal of a user Ceased WO2024000232A1 (en)

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PCT/CN2022/102230 WO2024000232A1 (en) 2022-06-29 2022-06-29 A method and a computing device for evaluating protection effect of a protector composition to be applied on keratin materal of a user
CN202280097601.1A CN119584913A (en) 2022-06-29 2022-06-29 Method and computing device for evaluating the protective effect of a protectant composition to be applied to a user's keratinous material
FR2208090A FR3137455B1 (en) 2022-06-29 2022-08-04 A method and computer device for evaluating the protective effect of a protective composition to be applied to a user's keratinous material

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US20160374917A1 (en) * 2014-01-20 2016-12-29 Cor S.A.R.L. Skin protector
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CN103284909A (en) * 2013-05-29 2013-09-11 薛羽佳 Emulsifying agent-free protective cream
US20160374917A1 (en) * 2014-01-20 2016-12-29 Cor S.A.R.L. Skin protector
US20180071190A1 (en) * 2015-03-25 2018-03-15 Gct Gmbh Cosmetic product and concentrate for producing the cosmetic product
WO2018193565A1 (en) * 2017-04-19 2018-10-25 花王株式会社 Method for evaluating impact of test substance or product on skin
CN111249209A (en) * 2020-03-30 2020-06-09 广东芭薇生物科技股份有限公司 Moisturizing repair cream and preparation method thereof

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