WO2023280770A1 - Microcapsule for use in the treatment of tooth misalignment by means of plastic splints or aligners - Google Patents

Microcapsule for use in the treatment of tooth misalignment by means of plastic splints or aligners Download PDF

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Publication number
WO2023280770A1
WO2023280770A1 PCT/EP2022/068431 EP2022068431W WO2023280770A1 WO 2023280770 A1 WO2023280770 A1 WO 2023280770A1 EP 2022068431 W EP2022068431 W EP 2022068431W WO 2023280770 A1 WO2023280770 A1 WO 2023280770A1
Authority
WO
WIPO (PCT)
Prior art keywords
microcapsules
treatment
aligners
microcapsule
plastic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2022/068431
Other languages
French (fr)
Inventor
Christoph Brandes
Jonathan Merlin Van Kempen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sirona Dental Systems GmbH
Dentsply Sirona Inc
Original Assignee
Sirona Dental Systems GmbH
Dentsply Sirona Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sirona Dental Systems GmbH, Dentsply Sirona Inc filed Critical Sirona Dental Systems GmbH
Priority to JP2024500254A priority Critical patent/JP2024523710A/en
Priority to US18/576,575 priority patent/US20240335268A1/en
Publication of WO2023280770A1 publication Critical patent/WO2023280770A1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C9/00—Impression cups, i.e. impression trays; Impression methods
    • A61C9/0006—Impression trays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C19/00—Dental auxiliary appliances
    • A61C19/04—Measuring instruments specially adapted for dentistry
    • A61C19/05—Measuring instruments specially adapted for dentistry for determining occlusion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C19/00—Dental auxiliary appliances
    • A61C19/04—Measuring instruments specially adapted for dentistry
    • A61C19/05—Measuring instruments specially adapted for dentistry for determining occlusion
    • A61C19/052—Measuring instruments specially adapted for dentistry for determining occlusion with tracing appliances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C7/00—Orthodontics, i.e. obtaining or maintaining the desired position of teeth, e.g. by straightening, evening, regulating, separating, or by correcting malocclusions
    • A61C7/08—Mouthpiece-type retainers or positioners, e.g. for both the lower and upper arch
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01L—MEASURING FORCE, STRESS, TORQUE, WORK, MECHANICAL POWER, MECHANICAL EFFICIENCY, OR FLUID PRESSURE
    • G01L1/00—Measuring force or stress, in general
    • G01L1/24—Measuring force or stress, in general by measuring variations of optical properties of material when it is stressed, e.g. by photoelastic stress analysis using infrared, visible light, ultraviolet
    • G01L1/247—Measuring force or stress, in general by measuring variations of optical properties of material when it is stressed, e.g. by photoelastic stress analysis using infrared, visible light, ultraviolet using distributed sensing elements, e.g. microcapsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C2201/00—Material properties
    • A61C2201/002—Material properties using colour effect, e.g. for identification purposes

Definitions

  • the present invention relates to orthodontic treatment methods, in particular to the treatment of malocclusions/misalignments by means of plastic splints or aligner therapy.
  • Aligner therapy is an orthodontic treatment method for the largely invisible treatment of mild to severe tooth misalignments that works with a sequence of individually manufactured, thin and transparent plastic splints (aligner).
  • the plastic splints are manufactured by deep drawing of thermoform foils or by additive manufacturing processes such as 3D printing.
  • the aligners For the success of the therapy, it is necessary that the aligners apply a sufficiently high force on the tooth. In the course of wearing the aligner, the plastic material from which the aligner was manufactured deforms. As a result, the force applied to the tooth gives way and an effective therapy can no longer be guaranteed. Therefore, the dentist uses a new aligner at regular intervals so that the therapy can be continued successfully.
  • the objective of the present invention is to provide microcapsules with which the efficacy of the therapy can be determined, and the progress of the therapy can be monitored.
  • the microcapsule according to claim 1 can be used in the treatment of tooth malocclusions/misalignments by means of plastic splints or aligners.
  • the microcapsule is a few pm in size (preferably 0.5 pm -200pm) and has a shell made of plastic, glass or ceramic.
  • the shell is filled inside with a biocompatible liquid. The shell ruptures when it experiences a defined force and the liquid, which can be detected optically preferably by a color change or UV light, is released.
  • the microcapsule is applied between the tooth and the inner side of the aligner.
  • the microcapsules can preferably be applied in various ways: e.g., as a spray, paste, powder, foil, or adhesive foil.
  • the microcapsules can be applied not only by the physician, but by the patient.
  • the physician can determine the effectiveness of the therapy and follow the progress of the therapy.
  • the patient can determine when to change the aligner and visit the physician or change it according to the instructions for use.
  • the present invention it is also possible to determine whether the force on the teeth falls below or exceeds a necessary limit value during the course of wearing the aligner.
  • the determination of the force can be take place very locally.
  • the physician/patient it is further made possible for the physician/patient to have the time of changing the aligner visually indicated by means of the microcapsules.
  • the microcapsule is filled with a colored liquid to create a color effect and allow the physician/patient to visualize when it breaks.
  • the colors in the microcapsules may be transparent in the visible wavelength range and acquire their hue only after the microcapsule breaks.
  • the color change in this case can result from a change in pH or oxidation of the dye.
  • the color change may be possible by the reaction of two or more used substances in the microcapsules with the same or different sensitivities/forces for rupture.
  • a combination or mixtures of different types of microcapsules with different colors, and each with different sensitivities/forces for rupture can be used to achieve a force resolution and to visualize this to the physician/patient. This allows a wider range of forces to be determined.
  • Fig. 1 - shows a schematic cross-sectional view of a microcapsule according to one embodiment of the invention
  • Fig. 2 - shows a schematic view of an aligner from below on whose inner side microcapsules have been applied;
  • Fig. 3 - shows a schematic front view of an aligner with microcapsules applied to the inner side.
  • Fig.l shows a microcapsule (1) according to one embodiment.
  • microcapsules (1) are used in the treatment of tooth malocclusions or misalignments by means of plastic splints (5) or aligners (5). These are a few pm in size and each has a shell (2) made of plastic or glass or ceramic.
  • the shell (2) is filled with a liquid (3) on the inside. Furthermore, the shell (2) breaks open when it experiences a defined force, and the liquid (3), which can be detected optically preferably by a color change or UV light, is released.
  • the microcapsules (1) can be filled with a liquid (3) which is or becomes colored upon release.
  • different microcapsules (1) are combined. Depending on the intended marking and color, differently filled or differently sensitive microcapsules (1) can be used. Different dyes (4) can be used with different sensitive microcapsules (1), for example a yellow and a green dye, which turn blue when released together. Thus, a force resolution can be achieved.
  • Microcapsule (1) according to type A reacts at 0, 5 MPa and turns yellow
  • Microcapsule (1) according to type B reacts at 1.0 MPa and turns green At stresses below 0.5MPa, no coloration occurs. At stresses between 0.5MPa-1.0MPa, yellow coloration occurs. At stresses >1.0MPa, blue coloration occurs (i.e. yellow + green). Three or more different microcapsules (1) can also be combined for an even wider force resolution.
  • the microcapsules (1) are provided as a spray, a paste, a film, preferably an adhesive film, or a powder.
  • the spray, paste, foil and powder can be manufactured, for example, from different types of microcapsules (1) or, alternatively, from only one type of microcapsules (1).

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dentistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)
  • Dental Preparations (AREA)

Abstract

The present invention relates to a microcapsule (1) for use in the treatment of dental malocclusions/misalignments by means of plastic splints (5) or aligners (5), characterized in that the microcapsule (1) is a few µm, preferably 0.5 µm to 200 µm in size and has a shell (2) made of plastic or glass or ceramic, the shell (2) is filled with a liquid (3) in the interior, and the shell (2) breaks open when it experiences a defined force and releases the liquid (3), which can be detected optically, preferably by a color change or illumination with UV light.

Description

MICROCAPSULE FOR USE IN THE TREATMENT OF TOOTH MISALIGNMENT BY MEANS OF PLASTIC SPLINTS OR ALIGNERS
The entire content of the priority application EP21183816.4 is hereby incorporated by reference to this international application under the provisions of the PCT.
TECHNICAL FIELD OF THE INVENTION
The present invention relates to orthodontic treatment methods, in particular to the treatment of malocclusions/misalignments by means of plastic splints or aligner therapy.
BACKGROUND OF THE INVENTION
Aligner therapy is an orthodontic treatment method for the largely invisible treatment of mild to severe tooth misalignments that works with a sequence of individually manufactured, thin and transparent plastic splints (aligner). The plastic splints are manufactured by deep drawing of thermoform foils or by additive manufacturing processes such as 3D printing.
For the success of the therapy, it is necessary that the aligners apply a sufficiently high force on the tooth. In the course of wearing the aligner, the plastic material from which the aligner was manufactured deforms. As a result, the force applied to the tooth gives way and an effective therapy can no longer be guaranteed. Therefore, the dentist uses a new aligner at regular intervals so that the therapy can be continued successfully.
It is important for the effectiveness of the therapy that the aligners are of consistent quality over the duration of use, as possible.
DISCLOSURE OF THE INVENTION
Currently, the inventors are not aware of any prior art with which the physician/patient can easily determine the effectiveness of the treatment and track the progress of the treatment and, for example, determine the changeover time for a new aligner.
The objective of the present invention is to provide microcapsules with which the efficacy of the therapy can be determined, and the progress of the therapy can be monitored.
This objective has been achieved by the microcapsule according to claim 1. The subject- matters of the dependent claims relate to further developments and preferred embodiments. The microcapsule according to the invention can be used in the treatment of tooth malocclusions/misalignments by means of plastic splints or aligners. The microcapsule is a few pm in size (preferably 0.5 pm -200pm) and has a shell made of plastic, glass or ceramic. The shell is filled inside with a biocompatible liquid. The shell ruptures when it experiences a defined force and the liquid, which can be detected optically preferably by a color change or UV light, is released.
The microcapsule is applied between the tooth and the inner side of the aligner. The microcapsules can preferably be applied in various ways: e.g., as a spray, paste, powder, foil, or adhesive foil.
The microcapsules can be applied not only by the physician, but by the patient. The physician can determine the effectiveness of the therapy and follow the progress of the therapy. The patient can determine when to change the aligner and visit the physician or change it according to the instructions for use.
According to the present invention, it is possible to determine whether the minimum necessary force is applied to the tooth by the aligners.
According to the present invention, it is also possible to determine whether the force on the teeth falls below or exceeds a necessary limit value during the course of wearing the aligner. The determination of the force can be take place very locally.
According to the present invention, it is further made possible for the physician/patient to have the time of changing the aligner visually indicated by means of the microcapsules.
Preferably, the microcapsule is filled with a colored liquid to create a color effect and allow the physician/patient to visualize when it breaks. The colors in the microcapsules may be transparent in the visible wavelength range and acquire their hue only after the microcapsule breaks. The color change in this case can result from a change in pH or oxidation of the dye. Also, the color change may be possible by the reaction of two or more used substances in the microcapsules with the same or different sensitivities/forces for rupture.
Preferably, a combination or mixtures of different types of microcapsules with different colors, and each with different sensitivities/forces for rupture can be used to achieve a force resolution and to visualize this to the physician/patient. This allows a wider range of forces to be determined. BRIEF DESCRIPTION OF THE DRAWINGS
In the following description, the present invention will be explained in more detail by means of exemplary embodiments with reference to the drawings, whereby
Fig. 1 - shows a schematic cross-sectional view of a microcapsule according to one embodiment of the invention;
Fig. 2 - shows a schematic view of an aligner from below on whose inner side microcapsules have been applied;
Fig. 3 - shows a schematic front view of an aligner with microcapsules applied to the inner side.
The reference numbers shown in the drawings designate the elements listed below, which are referred to in the following description of the exemplary embodiments.
1. Microcapsule
2. Shell
3. Liquid
4. Dye
5. Aligner/ Plastic splint
Fig.l shows a microcapsule (1) according to one embodiment. According to the present invention, microcapsules (1) are used in the treatment of tooth malocclusions or misalignments by means of plastic splints (5) or aligners (5). These are a few pm in size and each has a shell (2) made of plastic or glass or ceramic. The shell (2) is filled with a liquid (3) on the inside. Furthermore, the shell (2) breaks open when it experiences a defined force, and the liquid (3), which can be detected optically preferably by a color change or UV light, is released.
According to a preferred embodiment, the microcapsules (1) can be filled with a liquid (3) which is or becomes colored upon release.
For the successful application of an aligner (5), it must apply forces between 0.05N and 5N to a tooth, depending on the planned treatment. This results in a compressive stress X=
0.01 to 1 MPa which occurs between the tooth and the aligner (5). If the microcapsules (1), which are sensitive to the compressive stress X, are applied between the tooth and the aligner, a liquid discharge, preferably coloration, occurs when the force and thus the stress is reached. If the force is not reached, no liquid (3) is released, and no color effect occurs.
According to a preferred embodiment, different microcapsules (1) are combined. Depending on the intended marking and color, differently filled or differently sensitive microcapsules (1) can be used. Different dyes (4) can be used with different sensitive microcapsules (1), for example a yellow and a green dye, which turn blue when released together. Thus, a force resolution can be achieved.
This is explained with the following example:
Microcapsule (1) according to type A reacts at 0, 5 MPa and turns yellow
Microcapsule (1) according to type B reacts at 1.0 MPa and turns green At stresses below 0.5MPa, no coloration occurs. At stresses between 0.5MPa-1.0MPa, yellow coloration occurs. At stresses >1.0MPa, blue coloration occurs (i.e. yellow + green). Three or more different microcapsules (1) can also be combined for an even wider force resolution.
The application of the microcapsules (1) can be carried out in various ways. According to different embodiments, the microcapsules (1) are provided as a spray, a paste, a film, preferably an adhesive film, or a powder. The spray, paste, foil and powder can be manufactured, for example, from different types of microcapsules (1) or, alternatively, from only one type of microcapsules (1).

Claims

1. Microcapsule (1) for use in the treatment of dental malocclusions by means of plastic splints (5) or aligners (5), characterized in that the microcapsule (1) has a size of a few pm, preferably 0.5 pm to 200 pm, and has a shell (2) made of plastic or glass or ceramic, the shell (2) is filled in the interior with a liquid (3), and the shell (2) breaks open when it experiences a defined force and releases the liquid (3), which can be detected optically preferably by a color change or illumination with UV light.
2. Microcapsule (1) according to claim 1, characterized in that the filled liquid (3) is/becomes colored upon release.
3. A combination of microcapsules (1) according to any one of the preceding claims, characterized in that the microcapsules (1) have liquid (3) with different colors on release and each break open at differently defined forces.
4. A spray for use in the treatment of dental malocclusions by plastic splints or aligners characterized in that the spray comprises a type or combination of different types of microcapsules (1) according to any one of the preceding claims.
5. A paste for use in the treatment of dental malocclusions by plastic splints or aligners characterized in that the paste comprises a type or combination of different types of microcapsules (1) according to any one of the preceding claims 1 to 3.
6. A foil for use in the treatment of dental malocclusions by plastic splints or aligners characterized in that the foil comprises a type or combination of different types of microcapsules (1) according to any of the preceding claims 1 to 3.
7. The film according to claim 6, characterized in that the film is adhesive.
8. A powder for use in the treatment of dental malocclusions by plastic splints or aligners characterized in that the powder comprises a type or combination of different types of microcapsules (1) according to any one of the preceding claims 1 to 3.
PCT/EP2022/068431 2021-07-05 2022-07-04 Microcapsule for use in the treatment of tooth misalignment by means of plastic splints or aligners Ceased WO2023280770A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2024500254A JP2024523710A (en) 2021-07-05 2022-07-04 Microcapsules for use in the treatment of dental misalignment with plastic splints or aligners
US18/576,575 US20240335268A1 (en) 2021-07-05 2022-07-04 Microcapsule for use in the treatment of tooth misalignment by means of plastic splints or aligners

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP21183816.4 2021-07-05
EP21183816.4A EP4140441B1 (en) 2021-07-05 2021-07-05 Microcapsule for use in the treatment of tooth misalignment by means of plastic splints or aligners

Publications (1)

Publication Number Publication Date
WO2023280770A1 true WO2023280770A1 (en) 2023-01-12

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PCT/EP2022/068431 Ceased WO2023280770A1 (en) 2021-07-05 2022-07-04 Microcapsule for use in the treatment of tooth misalignment by means of plastic splints or aligners

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Country Link
US (1) US20240335268A1 (en)
EP (1) EP4140441B1 (en)
JP (1) JP2024523710A (en)
WO (1) WO2023280770A1 (en)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3469439A (en) * 1968-02-21 1969-09-30 Sanford B Roberts Means for measuring distributed forces using microcapsules
US5309196A (en) * 1981-11-12 1994-05-03 The Mead Corporation Transfer imaging system
US5474967A (en) * 1992-10-15 1995-12-12 Fuji Photo Film Co., Ltd. Pressure-sensitive recording sheet and occlusion pressure detecting sheet
US5941256A (en) * 1996-12-24 1999-08-24 Gillette Canada Inc. Dental hygiene article
US20090117507A1 (en) * 2000-09-21 2009-05-07 Align Technology, Inc. Systems and methods for dental appliance compliance indication
US20170100219A1 (en) * 2009-01-15 2017-04-13 Medentic S.A. Impression tray, and method for capturing structures, arrangements or shapes, in particular in the mouth or human body

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6386864B1 (en) * 2000-06-30 2002-05-14 Align Technology, Inc. Stress indicators for tooth positioning appliances
US20060063125A1 (en) * 2003-04-22 2006-03-23 Hamilton Timothy F Method and device for enhanced dental articulation
US7147466B1 (en) * 2003-10-24 2006-12-12 Dentsply International, Inc. Pressure indicator gel system and method therefore
US20200060789A1 (en) * 2018-08-24 2020-02-27 Rohit C. Sachdeva Modular orthodontic devices and methods for treatment
CN113905812A (en) * 2019-06-04 2022-01-07 3M创新有限公司 Microcapsules having a porous or hollow core and a shell comprising a component that releases a gas upon contact with an acid
US20240299136A1 (en) * 2021-07-05 2024-09-12 Dentsply Sirona Inc. Plastic splints or aligners for use in the treatment of malocclusions based on force measurement
US12285304B2 (en) * 2022-02-10 2025-04-29 Exocad Gmbh Testing model for testing fitting of a dental restoration

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3469439A (en) * 1968-02-21 1969-09-30 Sanford B Roberts Means for measuring distributed forces using microcapsules
US5309196A (en) * 1981-11-12 1994-05-03 The Mead Corporation Transfer imaging system
US5474967A (en) * 1992-10-15 1995-12-12 Fuji Photo Film Co., Ltd. Pressure-sensitive recording sheet and occlusion pressure detecting sheet
US5941256A (en) * 1996-12-24 1999-08-24 Gillette Canada Inc. Dental hygiene article
US20090117507A1 (en) * 2000-09-21 2009-05-07 Align Technology, Inc. Systems and methods for dental appliance compliance indication
US20170100219A1 (en) * 2009-01-15 2017-04-13 Medentic S.A. Impression tray, and method for capturing structures, arrangements or shapes, in particular in the mouth or human body

Also Published As

Publication number Publication date
JP2024523710A (en) 2024-06-28
EP4140441B1 (en) 2026-03-04
US20240335268A1 (en) 2024-10-10
EP4140441A1 (en) 2023-03-01

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