WO2023098697A3 - 体外生物合成的反应装置以及体外生物合成方法 - Google Patents

体外生物合成的反应装置以及体外生物合成方法 Download PDF

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Publication number
WO2023098697A3
WO2023098697A3 PCT/CN2022/135274 CN2022135274W WO2023098697A3 WO 2023098697 A3 WO2023098697 A3 WO 2023098697A3 CN 2022135274 W CN2022135274 W CN 2022135274W WO 2023098697 A3 WO2023098697 A3 WO 2023098697A3
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WO
WIPO (PCT)
Prior art keywords
reaction
vitro biosynthesis
vitro
reaction apparatus
biosynthesis
Prior art date
Application number
PCT/CN2022/135274
Other languages
English (en)
French (fr)
Other versions
WO2023098697A2 (zh
Inventor
郭敏
陈文芳
于雪
Original Assignee
康码（上海）生物科技有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CN202210093573.8A external-priority patent/CN114471367A/zh
Application filed by 康码（上海）生物科技有限公司 filed Critical 康码（上海）生物科技有限公司
Priority to KR1020247021154A priority Critical patent/KR20240116761A/ko
Publication of WO2023098697A2 publication Critical patent/WO2023098697A2/zh
Publication of WO2023098697A3 publication Critical patent/WO2023098697A3/zh

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/28—Moving reactors, e.g. rotary drums
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0006—Controlling or regulating processes
    • B01J19/0013—Controlling the temperature of the process
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0053—Details of the reactor
    • B01J19/006—Baffles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0053—Details of the reactor
    • B01J19/0066—Stirrers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J4/00—Feed or outlet devices; Feed or outlet control devices
    • B01J4/001—Feed or outlet devices as such, e.g. feeding tubes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2208/00—Processes carried out in the presence of solid particles; Reactors therefor
    • B01J2208/00796—Details of the reactor or of the particulate material
    • B01J2208/00823—Mixing elements
    • B01J2208/00831—Stationary elements
    • B01J2208/0084—Stationary elements inside the bed, e.g. baffles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00761—Details of the reactor
    • B01J2219/00763—Baffles
    • B01J2219/00765—Baffles attached to the reactor wall

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)

Abstract

一种体外生物合成的反应装置以及体外生物合成方法。体外生物合成的反应装置包括：反应腔本体（10）用于容纳蛋白合成反应液以进行体外生物合成的反应，反应腔本体（10）设置有开口部（10a），开口部（10a）具有用于让合成用反应液进入反应腔本体（10）内的进料口和让反应后的产物排出的出料口；分隔部（20）用于对反应腔本体（10）的内部空间进行不完全地分隔。
PCT/CN2022/135274 2021-11-30 2022-11-30 体外生物合成的反应装置以及体外生物合成方法 WO2023098697A2 (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020247021154A KR20240116761A (ko) 2021-11-30 2022-11-30 체외 생합성을 위한 반응장치 및 체외 생합성 방법

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
CN202111448968 2021-11-30
CN202111448968.7 2021-11-30
CN202210093573.8A CN114471367A (zh) 2021-11-30 2022-01-26 一种卧式自搅拌体外蛋白合成反应器的罐盖集成式进排气装置
CN202210095041.8A CN114307940A (zh) 2021-11-30 2022-01-26 一种卧式自搅拌体外蛋白合成反应器的罐体装置
CN202210095041.8 2022-01-26
CN202210093587.X 2022-01-26
CN202210093573.8 2022-01-26
CN202210093587.XA CN114247415A (zh) 2021-11-30 2022-01-26 一种卧式自搅拌体外蛋白合成反应器及体外蛋白合成方法
CN202210239438.XA CN114405455A (zh) 2021-11-30 2022-03-11 体外生物合成的反应装置以及体外生物合成方法
CN202210239438.X 2022-03-11
CN202220528915.X 2022-03-11
CN202220528915.XU CN219279864U (zh) 2021-11-30 2022-03-11 生物反应器以及相应的分隔件、反应装置和壳体

Publications (2)

Publication Number Publication Date
WO2023098697A2 WO2023098697A2 (zh) 2023-06-08
WO2023098697A3 true WO2023098697A3 (zh) 2023-08-17

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Country Status (2)

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KR (1) KR20240116761A (zh)
WO (1) WO2023098697A2 (zh)

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106902663A (zh) * 2017-04-01 2017-06-30 四川群青新材料科技有限公司 流化式高效混匀静态混合器
GB2550173A (en) * 2016-05-11 2017-11-15 Perkins Engines Co Ltd Mixer for after-treatment system
CN207520990U (zh) * 2017-09-22 2018-06-22 地龙力生物工程（天津）有限公司 一种地龙蛋白多肽缩水合成装置
CN108636333A (zh) * 2018-05-18 2018-10-12 苏州市金翔钛设备有限公司 一种混料氧化反应设备
WO2019086649A1 (de) * 2017-11-06 2019-05-09 Michael Niederbacher Pfropfenstrom-fermenter einer biogasanlage
CN212335181U (zh) * 2020-04-30 2021-01-12 天津二商迎宾肉类食品有限公司 一种生物发酵合成一体反应装置
CN114247415A (zh) * 2021-11-30 2022-03-29 康码（上海）生物科技有限公司 一种卧式自搅拌体外蛋白合成反应器及体外蛋白合成方法

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2550173A (en) * 2016-05-11 2017-11-15 Perkins Engines Co Ltd Mixer for after-treatment system
CN106902663A (zh) * 2017-04-01 2017-06-30 四川群青新材料科技有限公司 流化式高效混匀静态混合器
CN207520990U (zh) * 2017-09-22 2018-06-22 地龙力生物工程（天津）有限公司 一种地龙蛋白多肽缩水合成装置
WO2019086649A1 (de) * 2017-11-06 2019-05-09 Michael Niederbacher Pfropfenstrom-fermenter einer biogasanlage
CN108636333A (zh) * 2018-05-18 2018-10-12 苏州市金翔钛设备有限公司 一种混料氧化反应设备
CN212335181U (zh) * 2020-04-30 2021-01-12 天津二商迎宾肉类食品有限公司 一种生物发酵合成一体反应装置
CN114247415A (zh) * 2021-11-30 2022-03-29 康码（上海）生物科技有限公司 一种卧式自搅拌体外蛋白合成反应器及体外蛋白合成方法
CN114307940A (zh) * 2021-11-30 2022-04-12 康码（上海）生物科技有限公司 一种卧式自搅拌体外蛋白合成反应器的罐体装置
CN114405455A (zh) * 2021-11-30 2022-04-29 康码（上海）生物科技有限公司 体外生物合成的反应装置以及体外生物合成方法
CN114471367A (zh) * 2021-11-30 2022-05-13 康码（上海）生物科技有限公司 一种卧式自搅拌体外蛋白合成反应器的罐盖集成式进排气装置

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WO2023098697A2 (zh) 2023-06-08
KR20240116761A (ko) 2024-07-30

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