WO2022242123A1 - Mechanical ventilation man-machine asynchronous detection method and apparatus, and computer-readable storage medium - Google Patents

Mechanical ventilation man-machine asynchronous detection method and apparatus, and computer-readable storage medium Download PDF

Info

Publication number
WO2022242123A1
WO2022242123A1 PCT/CN2021/137606 CN2021137606W WO2022242123A1 WO 2022242123 A1 WO2022242123 A1 WO 2022242123A1 CN 2021137606 W CN2021137606 W CN 2021137606W WO 2022242123 A1 WO2022242123 A1 WO 2022242123A1
Authority
WO
WIPO (PCT)
Prior art keywords
data
layer
autoencoder
ventilation
neural network
Prior art date
Application number
PCT/CN2021/137606
Other languages
French (fr)
Chinese (zh)
Inventor
熊富海
颜延
谯小豪
李慧慧
王磊
刘语诗
陈达理
吴选昆
梁端
王博
曹修齐
Original Assignee
深圳先进技术研究院
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 深圳先进技术研究院 filed Critical 深圳先进技术研究院
Publication of WO2022242123A1 publication Critical patent/WO2022242123A1/en

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003Accessories therefor, e.g. sensors, vibrators, negative pressure
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06FELECTRIC DIGITAL DATA PROCESSING
    • G06F18/00Pattern recognition
    • G06F18/20Analysing
    • G06F18/24Classification techniques
    • G06F18/241Classification techniques relating to the classification model, e.g. parametric or non-parametric approaches
    • G06F18/2413Classification techniques relating to the classification model, e.g. parametric or non-parametric approaches based on distances to training or reference patterns
    • G06F18/24133Distances to prototypes
    • G06F18/24137Distances to cluster centroïds
    • G06F18/2414Smoothing the distance, e.g. radial basis function networks [RBFN]
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N3/00Computing arrangements based on biological models
    • G06N3/02Neural networks
    • G06N3/04Architecture, e.g. interconnection topology
    • G06N3/045Combinations of networks
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N3/00Computing arrangements based on biological models
    • G06N3/02Neural networks
    • G06N3/08Learning methods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/50General characteristics of the apparatus with microprocessors or computers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/50General characteristics of the apparatus with microprocessors or computers
    • A61M2205/52General characteristics of the apparatus with microprocessors or computers with memories providing a history of measured variating parameters of apparatus or patient

Definitions

  • the present application relates to the technical field of ventilator-mechanical ventilation, in particular to a method, a device and a computer-readable storage medium for detecting asynchronous detection of mechanical ventilation.
  • the defect of the prior art is that manual extraction of features and judgment of feature information to determine whether the air supply to the user by the ventilator is asynchronous, the efficiency is low, and the accuracy of manual processing of feature information to obtain detection results is low.
  • the application provides a mechanical ventilation human-machine asynchronous detection method, a device and a computer-readable storage medium to solve the technical problem of low efficiency and accuracy of the mechanical ventilation human-computer asynchronous detection method in the prior art.
  • the first technical solution provided by this application is: a mechanical ventilation man-machine asynchronous detection method, including: obtaining the ventilation data when the ventilator is performing mechanical ventilation; inputting the ventilation data into a preset autoencoder , to extract the characteristic data of the ventilation data; input the characteristic data into the preset convolutional neural network to output the human-machine asynchronous state of the ventilator.
  • a mechanical ventilation human-machine asynchronous detection device including: a memory and a processor; the memory is used to store program instructions, and the processor is used to execute the program instructions to realize the above-mentioned mechanical ventilation human-machine asynchronous detection method.
  • the third technical solution provided by the present application is: a computer-readable storage medium, the computer-readable storage medium stores program instructions, and when the program instructions are executed by a processor, the above-mentioned method for asynchronous detection of mechanical ventilation is implemented.
  • the human-machine asynchronous detection method of mechanical ventilation obtains the ventilation data when the ventilator performs mechanical ventilation; inputs the ventilation data into the preset autoencoder to extract the characteristic data of the ventilation data; and inputs the characteristic data into the preset Convolutional neural network to output the human-machine asynchronous state of the ventilator.
  • This application first extracts the characteristic data of the ventilation data based on the preset autoencoder, and then inputs the characteristic data into the preset convolutional neural network to identify the man-machine asynchronous state corresponding to the ventilation data, avoiding artificial
  • the steps of extracting features or manually identifying the man-machine asynchronous state reduce the consumption of human resources and improve the efficiency and accuracy of the man-machine asynchronous detection method for mechanical ventilation.
  • Fig. 1 is a schematic flow chart of an embodiment of a mechanical ventilation man-machine asynchronous detection method of the present application
  • Fig. 2 is a schematic structural diagram of an embodiment of the self-encoder of the present application
  • Fig. 3 is a schematic structural diagram of an embodiment of the one-dimensional convolutional neural network of the present application.
  • Fig. 4 is a schematic flowchart of another embodiment of the mechanical ventilation man-machine asynchronous detection method of the present application
  • Fig. 5 is a schematic flow chart of an embodiment of step S22 in the method for man-machine asynchronous detection of mechanical ventilation shown in Fig. 4;
  • Fig. 6 is a schematic diagram of the relationship between the training loss and the number of training iterations of an embodiment of the self-encoder of the present application
  • Fig. 7 is a schematic diagram of the result of the confusion matrix of an embodiment of the mechanical ventilation man-machine asynchronous detection method of the present application
  • Fig. 8 is a schematic structural diagram of an embodiment of the human-machine asynchronous detection device for mechanical ventilation of the present application
  • FIG. 9 is a schematic structural diagram of an embodiment of a computer-readable storage medium of the present application.
  • first and second in this application are only used for descriptive purposes, and cannot be understood as indicating or implying relative importance or implicitly specifying the quantity of indicated technical features.
  • plural means at least two, such as two, three, etc., unless otherwise specifically defined.
  • the terms “include” and “have”, as well as any variations thereof, are intended to cover a non-exclusive inclusion.
  • a process, method, system, product or device comprising a series of steps or units is not limited to the listed steps or units, but optionally also includes unlisted steps or units, or optionally further includes For other steps or units inherent in these processes, methods, products or apparatuses.
  • the present application first proposes a method for detecting asynchronous mechanical ventilation, as shown in FIG. 1 , which is a schematic flowchart of an embodiment of the method for detecting asynchronous mechanical ventilation according to the present application.
  • the ventilator is an important life device for respiratory function support, and is widely used in the intensive care department of the hospital, general departments or families, and is an important auxiliary support device for people with respiratory dysfunction .
  • the main function of the ventilator is to supply air to the patient when it detects that the patient needs to inhale, and to stop the supply of air to the patient when the patient needs to exhale. If the ventilator stops supplying air when the patient needs to inhale and supplies air to the patient when the patient needs to exhale, the ventilator can be considered to be asynchronous in the process of supplying air to the patient.
  • Step S11 Obtain ventilation data when the ventilator performs mechanical ventilation.
  • a preset sampling frequency (for example: 50 Hz) may be used to collect ventilation data of a ventilator undergoing mechanical ventilation.
  • the ventilation data may at least include one of airflow velocity data, airflow channel pressure data and air flow data, wherein the airflow velocity data is used to describe the velocity of the airflow of the ventilator during mechanical ventilation, and the airflow channel pressure is used to describe the airflow velocity of the ventilator.
  • the air pressure in the delivered airflow channel during mechanical ventilation, and the airflow data are used to describe the amount of airflow delivered by the ventilator during mechanical ventilation.
  • related sensors can be set in the air supply pipeline used by the ventilator to supply air to the patient, so as to obtain the airflow velocity data, airflow channel pressure data and air flow data of the ventilator during mechanical ventilation.
  • Step S12 Input the ventilation data into a preset autoencoder to extract characteristic data of the ventilation data.
  • the ventilation data acquired in step S11 may be input into an autoencoder that has been trained in advance, so that the autoencoder can extract feature information from the ventilation data to generate feature data.
  • the extraction of feature information based on autoencoders can not only save a lot of valuable human resources, but also avoid errors caused by human errors, which can greatly improve the efficiency and accuracy of feature information extraction.
  • FIG. 2 is a schematic structural diagram of an embodiment of an autoencoder of the present application.
  • Self-encoder 20 comprises: self-encoder input layer 201, first hidden layer 202, second hidden layer 203, third hidden layer 204, fourth hidden layer 205, fifth hidden layer 206 and self-encoder output layer 207;
  • the self-encoder input layer 201, the first hidden layer 202, the second hidden layer 203, the third hidden layer 204, the fourth hidden layer 205, the fifth hidden layer 206 and the self-encoder output layer 207 are sequentially connected, and the self-encoder input
  • the layer 201 is used to receive ventilation data
  • the autoencoder output layer 207 is the output layer of the autoencoder during training
  • the third hidden layer 204 is used to output feature data.
  • Step S13 Input the feature data into the preset convolutional neural network to output the human-machine asynchronous state of the ventilator.
  • the feature data extracted in step S12 can be input into the convolutional neural network that has completed relevant training in advance, so that the convolutional neural network can identify the asynchronous state of man and machine through the processing of feature data, and then can pass human
  • the Ventilator Asynchronous Status determines whether there is asynchronous air supply to the ventilator.
  • the man-machine asynchronous state includes at least double-trigger state, invalid inspiratory effort state and normal state, and may also include other types of man-machine asynchronous states, which are not limited here.
  • the ventilator may capture the patient’s inspiratory movements twice in a row, which will then trigger the patient’s mechanical ventilation twice in a row, resulting in an oversupply situation.
  • the ventilator is in a dual-trigger state at this time; in the second case, the patient’s breathing force is weak, and the ventilator may always or often fail to capture the patient’s inspiratory action, and thus cannot trigger the patient’s mechanical ventilation action, thus
  • the ventilator normally supplies air when the patient needs to inhale, and stops supplying air when the patient needs to exhale.
  • the machine is in normal condition.
  • the man-machine asynchronous detection method for mechanical ventilation of the present application can quickly and accurately identify the abnormal state (double trigger state and invalid inspiratory effort state) or normal state in the above three situations.
  • FIG. 3 is a schematic structural diagram of an embodiment of a one-dimensional convolutional neural network of the present application.
  • the convolutional neural network is a one-dimensional convolutional neural network 30;
  • One-dimensional convolutional neural network 30 includes: one-dimensional convolutional neural network input layer 301, first one-dimensional convolutional layer 302, first maximum pooling layer 303, second one-dimensional convolutional layer 304, second maximum pooling Layer 305, the third one-dimensional convolutional layer 306, the first fully connected layer 307, the second fully connected layer 308 and the one-dimensional convolutional neural network output layer 309;
  • One-dimensional convolution neural network input layer 301, first one-dimensional convolution layer 302, first maximum pooling layer 303, second one-dimensional convolution layer 304, second maximum pooling layer 305, third one-dimensional convolution Layer 306, the first fully connected layer 307, the second fully connected layer 308 and the one-dimensional convolutional neural network output layer 309 are sequentially connected, the one-dimensional convolutional neural network input layer 301 is used to receive feature data, and the one-dimensional convolutional neural network The output layer 309 is used to output the human-machine asynchronous state.
  • FIG. 4 is a schematic flow chart of another embodiment of the method for detecting human-machine asynchrony in mechanical ventilation of the present application.
  • the respiratory monitoring method of this embodiment specifically further includes the following steps:
  • Step S21 Obtain training data.
  • a ventilator and a simulated lung can be used to simulate patients with acute respiratory distress syndrome (ARDS) facing different man-machines when using a ventilator.
  • ARDS acute respiratory distress syndrome
  • Respiratory events in the asynchronous state including at least: double-trigger state, invalid inspiratory effort state and normal state
  • obtain simulated ventilation data when the ventilator is in different man-machine asynchronous states based on multiple respiratory events, and use the different Simulated ventilation data under respiratory events were used as training data.
  • Step S22 Perform preprocessing on the training data; wherein, the preprocessing includes at least marking the training data with man-machine asynchronous state.
  • Step S23 Input the preprocessed training data into the autoencoder to train the autoencoder.
  • the training data can be preprocessed first (including at least marking the training data corresponding to the man-machine asynchronous state of each training data), and then the autoencoder is trained based on the preprocessed training data, and After the training is completed, the output data of the third hidden layer (middle layer) of the trained self-encoder is used as the feature data of the ventilation data.
  • FIG. 4 is a schematic flow chart of another embodiment of the method for detecting human-machine asynchrony in mechanical ventilation of the present application.
  • Step S22 may specifically include: dividing the training data into multiple data segments, and marking each data segment with a man-machine asynchronous state.
  • Step S23 may specifically include: respectively inputting data corresponding to each man-machine asynchronous state into the autoencoder, so as to train the autoencoder.
  • FIG. 5 is a schematic flow chart of step S22 in the method for detecting the asynchronous detection of man-machine in mechanical ventilation shown in FIG. 4 .
  • Step S22 may specifically include the following steps:
  • Step S221 Divide the training data into multiple data segments.
  • Step S222 Completing the sampling points for each data segment, so that the number of sampling points in each data segment is the same.
  • Step S223 Standardize the data of each data segment by using the mean value and standard deviation of the data of each sampling point in each data segment.
  • Step S224 Carry out man-machine asynchronous state labeling for each data segment after normalization processing.
  • the filling of the above-mentioned sampling points may be to pad or truncate each piece of data so that the number of each data section is the same (same length). For example, each data section can be filled with zeros or deleted. The method of too many sampling points makes it have 100 sampling point data.
  • the calculation formula of the longest respiratory cycle signal length is as follows:
  • L len trainset +len testset ;
  • maxLen is the longest respiratory cycle signal length
  • len trainset is the data segment quantity of training data
  • len testset is the data segment quantity of test data
  • P x is the data segment of a training data or test data
  • test data is used for Autoencoders and Convolutional Neural Networks for testing purposes.
  • the longest respiratory cycle signal length can be calculated based on the above-mentioned longest respiratory cycle signal length calculation formula. If the longest respiratory cycle signal length is 100, each data segment can be filled with zeros or deleted. The method makes it have 100 sampling point data.
  • each data segment is standardized based on the mean value and standard deviation (or variance) of each sampling point data in each data segment.
  • the training data trains the autoencoder and the convolutional neural network, which is conducive to further improving the efficiency and accuracy of the autoencoder and convolutional neural network in feature extraction and/or recognition of human-machine asynchronous states.
  • N x is the sampling point data before normalization processing
  • is the mean value of the sampling point data in the data segment where the sampling point data is located
  • is the standard deviation of the sampling point data in the data segment where the sampling point data is located .
  • the training data and the ventilation data may include three types of data, namely air flow velocity data, air flow channel pressure data and air flow data, and may form three-dimensional data.
  • N in the formula of the above normalization process may refer to any one of F, P, and V.
  • Self-encoder may comprise: self-encoder input layer, first hidden layer, second hidden layer, third hidden layer, fourth hidden layer, fifth hidden layer and self-encoder output layer; self-encoder input layer, second hidden layer
  • the first hidden layer, the second hidden layer, the third hidden layer, the fourth hidden layer, the fifth hidden layer and the output layer of the autoencoder are sequentially connected.
  • the number of neurons in the first hidden layer, the second hidden layer, the third hidden layer, the fourth hidden layer, and the fifth hidden layer are 128, 64, 32, 64, and 128 respectively.
  • the data output by the third hidden layer can be used as the feature data extracted by the autoencoder based on the ventilation data, so as to extract the characteristics of the ventilation data as three-dimensional data, form one-dimensional feature data, and realize the feature
  • the extraction and dimensionality reduction of data is conducive to the rapid processing of the feature data by the subsequent convolutional neural network.
  • the convolutional neural network is a one-dimensional convolutional neural network;
  • the one-dimensional convolutional neural network includes: a one-dimensional convolutional neural network input layer, a first one-dimensional convolution layer, a first maximum pooling layer, a second one-dimensional convolution layer, the second maximum pooling layer, the third one-dimensional convolutional layer, the first fully connected layer, the second fully connected layer and the output layer of the one-dimensional convolutional neural network; the input layer of the one-dimensional convolutional neural network, the first one 1D convolutional layer, 1st max pooling layer, 2nd 1D convolutional layer, 2nd max pooling layer, 3rd 1D convolutional layer, 1st fully connected layer, 2nd fully connected layer and 1D convolution
  • the output layers of the convolutional neural network are sequentially connected, wherein a dropout layer may also be included between the first fully connected layer and the second fully connected layer to reduce the risk of overfitting in the convolutional neural network.
  • the one-dimensional feature data extracted by the autoencoder based on the training data can be input into the input layer of the one-dimensional convolutional neural network, and the label information corresponding to the training data (used to label the training The information of the human-machine asynchronous state corresponding to the data) is used as the output of the output layer of the one-dimensional convolutional neural network for training.
  • the one-dimensional convolutional neural network When using the one-dimensional convolutional neural network in practice, similar steps can be taken during training, and the one-dimensional feature data extracted by the autoencoder based on the ventilation data can be input into the input layer of the one-dimensional convolutional neural network to make the one-dimensional convolutional neural network
  • the network outputs the corresponding man-machine asynchronous state (that is, the man-machine asynchronous state corresponding to the acquired ventilation data).
  • using a one-dimensional convolutional neural network to process one-dimensional data in the process of respiratory monitoring can greatly improve the efficiency of respiratory monitoring.
  • FIG. 6 is a schematic diagram of the relationship between the autoencoder training loss and the number of training iterations in the present application.
  • A is the training loss curve of the airflow velocity data
  • B is the training loss curve of the airflow channel pressure data
  • C is the training loss curve of the air flow data.
  • FIG. 7 is a schematic diagram of the confusion matrix result of the human-machine asynchronous detection method for mechanical ventilation of the present application.
  • the human-machine asynchronous detection method for mechanical ventilation of the present application has an accurate detection probability of 100% for the double-trigger state or the invalid inspiratory effort state after training with a certain amount of training data, and the accurate detection probability for the normal state is 97%, there is a 3% probability that the normal state will be identified as a double-trigger state.
  • the accuracy rate of the human-machine asynchronous detection method for mechanical ventilation in this application is extremely high, and the accuracy rate can continue to improve with the increase of training data.
  • the man-machine asynchronous detection method for mechanical ventilation obtains the ventilation data when the ventilator performs mechanical ventilation; inputs the ventilation data into the preset autoencoder to extract the characteristic data of the ventilation data; and inputs the characteristic data into the preset Convolutional neural network to output the human-machine asynchronous state of the ventilator.
  • This application first extracts the characteristic data of the ventilation data based on the preset autoencoder, and then inputs the characteristic data into the preset convolutional neural network to identify the man-machine asynchronous state corresponding to the ventilation data, avoiding artificial
  • the steps of extracting features or manually identifying the man-machine asynchronous state reduce the consumption of human resources and improve the efficiency and accuracy of the man-machine asynchronous detection method for mechanical ventilation.
  • the present application further proposes a human-machine asynchronous detection device for mechanical ventilation, as shown in FIG. 8 , which is a schematic structural diagram of an embodiment of the human-computer asynchronous detection device for mechanical ventilation of the present application.
  • the apparatus 80 for detecting human-machine asynchrony of mechanical ventilation in this embodiment includes: a processor 81 , a memory 82 and a bus 83 .
  • the processor 81 and the memory 82 are connected to the bus 83 respectively.
  • the memory 82 stores program instructions, and the processor 81 is used to execute the program instructions to implement the method for detecting asynchronous mechanical ventilation in the above embodiments.
  • the processor 81 may also be called a CPU (Central Processing Unit, central processing unit).
  • the processor 81 may be an integrated circuit chip with signal processing capabilities.
  • the processor 81 can also be a general-purpose processor, a digital signal processor (DSP), an application-specific integrated circuit (ASIC), a field-programmable gate array (FPGA) or other programmable logic devices, discrete gate or transistor logic devices, discrete hardware components .
  • the general processor may be a microprocessor or the processor 81 may be any conventional processor or the like.
  • the asynchronous detection device for mechanical ventilation mentioned above may be a detection device independent of the ventilator, or a part of the ventilator, which is not limited here.
  • the human-machine asynchronous detection method of mechanical ventilation obtains the ventilation data when the ventilator performs mechanical ventilation; inputs the ventilation data into the preset autoencoder to extract the characteristic data of the ventilation data; and inputs the characteristic data into the preset Convolutional neural network to output the human-machine asynchronous state of the ventilator.
  • This application first extracts the characteristic data of the ventilation data based on the preset autoencoder, and then inputs the characteristic data into the preset convolutional neural network to identify the man-machine asynchronous state corresponding to the ventilation data, avoiding artificial
  • the steps of extracting features or manually identifying the man-machine asynchronous state reduce the consumption of human resources and improve the efficiency and accuracy of the man-machine asynchronous detection method for mechanical ventilation.
  • the present application further proposes a computer-readable storage medium, as shown in FIG. 9 , which is a structural schematic diagram of an embodiment of the computer-readable storage medium of the present application.
  • the computer-readable storage medium 90 stores program instructions 91 thereon, When the program instruction 91 is executed by the processor (not shown in the figure), the method for detecting the asynchronous detection of mechanical ventilation in the above-mentioned embodiments is realized.
  • the computer-readable storage medium 90 in this embodiment may be, but not limited to, a USB flash drive, an SD card, a PD optical drive, a mobile hard disk, a large-capacity floppy drive, a flash memory, a multimedia memory card, a server, and the like.
  • the man-machine asynchronous detection method for mechanical ventilation obtains the ventilation data when the ventilator performs mechanical ventilation; inputs the ventilation data into the preset autoencoder to extract the characteristic data of the ventilation data; and inputs the characteristic data into the preset Convolutional neural network to output the human-machine asynchronous state of the ventilator.
  • This application first extracts the characteristic data of the ventilation data based on the preset autoencoder, and then inputs the characteristic data into the preset convolutional neural network to identify the man-machine asynchronous state corresponding to the ventilation data, avoiding artificial
  • the steps of extracting features or manually identifying the man-machine asynchronous state reduce the consumption of human resources and improve the efficiency and accuracy of the man-machine asynchronous detection method for mechanical ventilation.
  • references to the terms “one embodiment,” “some embodiments,” “example,” “specific examples,” or “some examples” means that specific features described in connection with that embodiment or example , structure, material or characteristic is included in at least one embodiment or example of the present application.
  • the schematic representations of the above terms are not necessarily directed to the same embodiment or example.
  • the described specific features, structures, materials or characteristics may be combined in any suitable manner in any one or more embodiments or examples.
  • those skilled in the art can combine and combine different embodiments or examples and features of different embodiments or examples described in this specification without conflicting with each other.
  • first and second are used for descriptive purposes only, and cannot be interpreted as indicating or implying relative importance or implicitly specifying the quantity of indicated technical features.
  • the features defined as “first” and “second” may explicitly or implicitly include at least one of these features.
  • “plurality” means at least two, such as two, three, etc., unless otherwise specifically defined.
  • a "computer-readable medium” may be any device that can contain, store, communicate, propagate or transmit a program for use in or in conjunction with an instruction execution system, device or device.
  • computer-readable media include the following: electrical connection with one or more wires (electronic device), portable computer disk case (magnetic device), random access memory (RAM), Read Only Memory (ROM), Erasable and Editable Read Only Memory (EPROM or Flash Memory), Fiber Optic Devices, and Portable Compact Disc Read Only Memory (CDROM).
  • the computer-readable medium may even be paper or other suitable medium on which the program can be printed, since the program can be read, for example, by optically scanning the paper or other medium, followed by editing, interpretation or other suitable processing if necessary.
  • the program is processed electronically and stored in computer memory.

Landscapes

  • Engineering & Computer Science (AREA)
  • Theoretical Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Data Mining & Analysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Evolutionary Computation (AREA)
  • General Health & Medical Sciences (AREA)
  • Artificial Intelligence (AREA)
  • Molecular Biology (AREA)
  • Computing Systems (AREA)
  • Software Systems (AREA)
  • Biophysics (AREA)
  • Computational Linguistics (AREA)
  • Mathematical Physics (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Public Health (AREA)
  • Emergency Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Evolutionary Biology (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

A mechanical ventilation man-machine asynchronous detection method and apparatus, and a computer-readable storage medium, relating to the technical field of mechanical ventilation of ventilators. The method comprises: acquiring ventilation data when a ventilator performs mechanical ventilation (S11); inputting the ventilation data into a preset auto-encoder to extract feature data of the ventilation data (S12); and inputting the feature data into a preset convolutional neural network to output a man-machine asynchronous state of the ventilator (S13). It is beneficial to improve the efficiency and accuracy of the mechanical ventilation man-machine asynchronous detection method.

Description

机械通气人机异步检测方法、装置及计算机可读存储介质Mechanical ventilation human-computer asynchronous detection method, device and computer-readable storage medium 技术领域technical field
本申请涉及呼吸机机械通气技术领域,特别是涉及机械通气人机异步检测方法、装置及计算机可读存储介质。The present application relates to the technical field of ventilator-mechanical ventilation, in particular to a method, a device and a computer-readable storage medium for detecting asynchronous detection of mechanical ventilation.
背景技术Background technique
现有技术中,在检测呼吸机对用户进行的供气是否出现异步(即与用户的呼气或吸气不同步)时,常常需要本领域专家对各种异步情况下和正常情况下的特征信息进行人工提取和判别,以确定当前呼吸机供气和停止供气的动作是否分别与患者吸气和呼气的动作均同步。In the prior art, when detecting whether the air supply of the ventilator to the user is asynchronous (that is, not synchronous with the user's exhalation or inhalation), it is often necessary for experts in the field to analyze the characteristics of various asynchronous and normal conditions. The information is manually extracted and judged to determine whether the current gas supply and stop gas supply actions of the ventilator are synchronized with the patient's inhalation and exhalation actions respectively.
现有技术的缺陷在于,人工提取特征以及对特征信息进行判断以确定呼吸机对用户进行的供气是否出现异步,效率较低,且人工处理特征信息以得到检测结果的准确度较低。The defect of the prior art is that manual extraction of features and judgment of feature information to determine whether the air supply to the user by the ventilator is asynchronous, the efficiency is low, and the accuracy of manual processing of feature information to obtain detection results is low.
发明内容Contents of the invention
本申请提供机械通气人机异步检测方法、装置及计算机可读存储介质,以解决现有技术中机械通气人机异步检测方法的效率和准确度较低的技术问题。The application provides a mechanical ventilation human-machine asynchronous detection method, a device and a computer-readable storage medium to solve the technical problem of low efficiency and accuracy of the mechanical ventilation human-computer asynchronous detection method in the prior art.
为解决上述技术问题,本申请提供的第一个技术方案为:一种机械通气人机异步检测方法,包括:获取呼吸机进行机械通气时的通气数据;将通气数据输入预设的自编码器,以提取通气数据的特征数据;将特征数据输入预设的卷积神经网络,以输出呼吸机的人机异步状态。In order to solve the above technical problems, the first technical solution provided by this application is: a mechanical ventilation man-machine asynchronous detection method, including: obtaining the ventilation data when the ventilator is performing mechanical ventilation; inputting the ventilation data into a preset autoencoder , to extract the characteristic data of the ventilation data; input the characteristic data into the preset convolutional neural network to output the human-machine asynchronous state of the ventilator.
本申请提供的第二个技术方案为:一种机械通气人机异步检测装置,包括:存储器和处理器;存储器用于存储程序指令,处理器用于执行程序指令以实现上述机械通气人机异步检测方法。The second technical solution provided by this application is: a mechanical ventilation human-machine asynchronous detection device, including: a memory and a processor; the memory is used to store program instructions, and the processor is used to execute the program instructions to realize the above-mentioned mechanical ventilation human-machine asynchronous detection method.
本申请提供的第三个技术方案为:一种计算机可读存储介质,所述计算机可读存储介质存储有程序指令,所述程序指令被处理器执行时实现上述机械通气人机异步检测方法。The third technical solution provided by the present application is: a computer-readable storage medium, the computer-readable storage medium stores program instructions, and when the program instructions are executed by a processor, the above-mentioned method for asynchronous detection of mechanical ventilation is implemented.
本申请提供的机械通气人机异步检测方法,通过获取呼吸机进行机械通气时的通气数据;将通气数据输入预设的自编码器,以提取通气数据的特征数据; 将特征数据输入预设的卷积神经网络,以输出呼吸机的人机异步状态。本申请通过先基于预设的自编码器对通气数据的特征数据进行提取,再将该特征数据输入预设的卷积神经网络,以识别该通气数据所对应的人机异步状态,避免了人工提取特征或人工识别人机异步状态的步骤,降低了的人力资源的消耗,提高了机械通气人机异步检测方法的效率和准确度。The human-machine asynchronous detection method of mechanical ventilation provided by this application obtains the ventilation data when the ventilator performs mechanical ventilation; inputs the ventilation data into the preset autoencoder to extract the characteristic data of the ventilation data; and inputs the characteristic data into the preset Convolutional neural network to output the human-machine asynchronous state of the ventilator. This application first extracts the characteristic data of the ventilation data based on the preset autoencoder, and then inputs the characteristic data into the preset convolutional neural network to identify the man-machine asynchronous state corresponding to the ventilation data, avoiding artificial The steps of extracting features or manually identifying the man-machine asynchronous state reduce the consumption of human resources and improve the efficiency and accuracy of the man-machine asynchronous detection method for mechanical ventilation.
附图说明Description of drawings
为了更清楚地说明本发明实施例中的技术方案,下面将对实施例描述中所需要使用的附图作简单地介绍,显而易见地,下面描述中的附图仅仅是本发明的一些实施例,对于本领域普通技术人员来讲,在不付出创造性劳动的前提下,还可以根据这些附图获得其它的附图。In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings that need to be used in the description of the embodiments will be briefly introduced below. Obviously, the drawings in the following description are only some embodiments of the present invention. For those skilled in the art, other drawings can also be obtained based on these drawings without creative effort.
图1是本申请的机械通气人机异步检测方法的一实施例的流程示意图;Fig. 1 is a schematic flow chart of an embodiment of a mechanical ventilation man-machine asynchronous detection method of the present application;
图2是本申请的自编码器的一实施例的结构示意图;Fig. 2 is a schematic structural diagram of an embodiment of the self-encoder of the present application;
图3是本申请的一维卷积神经网络的一实施例的结构示意图;Fig. 3 is a schematic structural diagram of an embodiment of the one-dimensional convolutional neural network of the present application;
图4是本申请的机械通气人机异步检测方法的另一实施例的流程示意图;Fig. 4 is a schematic flowchart of another embodiment of the mechanical ventilation man-machine asynchronous detection method of the present application;
图5是图4所示机械通气人机异步检测方法中的步骤S22的一实施例的具体流程示意图;Fig. 5 is a schematic flow chart of an embodiment of step S22 in the method for man-machine asynchronous detection of mechanical ventilation shown in Fig. 4;
图6是本申请的自编码器的一实施例的训练损失与训练迭代次数关系示意图;Fig. 6 is a schematic diagram of the relationship between the training loss and the number of training iterations of an embodiment of the self-encoder of the present application;
图7是本申请的机械通气人机异步检测方法的一实施例的混淆矩阵结果示意图;Fig. 7 is a schematic diagram of the result of the confusion matrix of an embodiment of the mechanical ventilation man-machine asynchronous detection method of the present application;
图8是本申请的机械通气人机异步检测装置的一实施例的结构示意图;Fig. 8 is a schematic structural diagram of an embodiment of the human-machine asynchronous detection device for mechanical ventilation of the present application;
图9是本申请的计算机可读存储介质的一实施例的结构示意图。FIG. 9 is a schematic structural diagram of an embodiment of a computer-readable storage medium of the present application.
具体实施方式Detailed ways
下面将结合本申请实施例中的附图,对本申请实施例中的技术方案进行清楚、完整地描述,显然,所描述的实施例仅仅是本申请一部分实施例,而不是全部的实施例。基于本申请中的实施例,本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例,均属于本申请保护的范围。The following will clearly and completely describe the technical solutions in the embodiments of the application with reference to the drawings in the embodiments of the application. Apparently, the described embodiments are only some of the embodiments of the application, not all of them. Based on the embodiments in this application, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the scope of protection of this application.
本申请中的术语“第一”、“第二”仅用于描述目的,而不能理解为指示或 暗示相对重要性或者隐含指明所指示的技术特征的数量。本申请的描述中,“多个”的含义是至少两个,例如两个,三个等,除非另有明确具体的限定。此外,术语“包括”和“具有”以及它们任何变形,意图在于覆盖不排他的包含。例如包含了一系列步骤或单元的过程、方法、系统、产品或设备没有限定于已列出的步骤或单元,而是可选地还包括没有列出的步骤或单元,或可选地还包括对于这些过程、方法、产品或设备固有的其它步骤或单元。The terms "first" and "second" in this application are only used for descriptive purposes, and cannot be understood as indicating or implying relative importance or implicitly specifying the quantity of indicated technical features. In the description of the present application, "plurality" means at least two, such as two, three, etc., unless otherwise specifically defined. Furthermore, the terms "include" and "have", as well as any variations thereof, are intended to cover a non-exclusive inclusion. For example, a process, method, system, product or device comprising a series of steps or units is not limited to the listed steps or units, but optionally also includes unlisted steps or units, or optionally further includes For other steps or units inherent in these processes, methods, products or apparatuses.
本申请首先提出一种机械通气人机异步检测方法,如图1所示,图1是本申请的机械通气人机异步检测方法的一实施例的流程示意图。The present application first proposes a method for detecting asynchronous mechanical ventilation, as shown in FIG. 1 , which is a schematic flowchart of an embodiment of the method for detecting asynchronous mechanical ventilation according to the present application.
需要说明的是,呼吸机是一种重要的用于呼吸功能支持的生命设备,被广泛应用于医院的重症监护科室、一般性科室或家庭中,是具有呼吸功能障碍的人员的重要辅助支持设备。呼吸机的主要功能是在检测到患者需要吸气时对患者进行供气,并在患者需要呼气时停止对患者的供气。若呼吸机在患者需要吸气时停止供气而在患者需要呼气时对患者进行供气,则可认为该呼吸机对患者的供气过程中出现了异步。It should be noted that the ventilator is an important life device for respiratory function support, and is widely used in the intensive care department of the hospital, general departments or families, and is an important auxiliary support device for people with respiratory dysfunction . The main function of the ventilator is to supply air to the patient when it detects that the patient needs to inhale, and to stop the supply of air to the patient when the patient needs to exhale. If the ventilator stops supplying air when the patient needs to inhale and supplies air to the patient when the patient needs to exhale, the ventilator can be considered to be asynchronous in the process of supplying air to the patient.
本实施例机械通气人机异步检测方法具体包括以下步骤:The human-machine asynchronous detection method for mechanical ventilation in this embodiment specifically includes the following steps:
步骤S11:获取呼吸机进行机械通气时的通气数据。Step S11: Obtain ventilation data when the ventilator performs mechanical ventilation.
本实施例中,可采用预设采样频率(如:50赫兹)对正在进行机械通气的呼吸机采集其通气数据。通气数据可至少包括气流流速数据、气流通道压力数据和气流量数据中的一种,其中,气流流速数据用于描述呼吸机在进行机械通气时的气流流动的速度,气流通道压力用于描述呼吸机在进行机械通气时的输送气流通道内的气压,气流量数据用于描述呼吸机在进行机械通气时所述送的气流的量。举例说明,可在呼吸机对患者进行供气时使用的供气管道中设置相关的传感器,以获得呼吸机在机械通气时的气流流速数据、气流通道压力数据和气流量数据。In this embodiment, a preset sampling frequency (for example: 50 Hz) may be used to collect ventilation data of a ventilator undergoing mechanical ventilation. The ventilation data may at least include one of airflow velocity data, airflow channel pressure data and air flow data, wherein the airflow velocity data is used to describe the velocity of the airflow of the ventilator during mechanical ventilation, and the airflow channel pressure is used to describe the airflow velocity of the ventilator. The air pressure in the delivered airflow channel during mechanical ventilation, and the airflow data are used to describe the amount of airflow delivered by the ventilator during mechanical ventilation. For example, related sensors can be set in the air supply pipeline used by the ventilator to supply air to the patient, so as to obtain the airflow velocity data, airflow channel pressure data and air flow data of the ventilator during mechanical ventilation.
步骤S12:将通气数据输入预设的自编码器,以提取通气数据的特征数据。Step S12: Input the ventilation data into a preset autoencoder to extract characteristic data of the ventilation data.
本实施例中,可将步骤S11中所获取的通气数据输入已预先完成相关训练的自编码器中,以使自编码器对通气数据中的特征信息进行提取而生成特征数据。基于自编码器进行特征信息的提取不仅可节省大量宝贵的人力资源,还可避免因人为失误所导致的错误出现,进而可大大提高提取特征信息的效率和准确度。In this embodiment, the ventilation data acquired in step S11 may be input into an autoencoder that has been trained in advance, so that the autoencoder can extract feature information from the ventilation data to generate feature data. The extraction of feature information based on autoencoders can not only save a lot of valuable human resources, but also avoid errors caused by human errors, which can greatly improve the efficiency and accuracy of feature information extraction.
可选的,如图2所示,图2是本申请的自编码器的一实施例的结构示意图。自编码器20包括:自编码器输入层201、第一隐层202、第二隐层203、第三隐层204、第四隐层205、第五隐层206和自编码器输出层207;Optionally, as shown in FIG. 2 , FIG. 2 is a schematic structural diagram of an embodiment of an autoencoder of the present application. Self-encoder 20 comprises: self-encoder input layer 201, first hidden layer 202, second hidden layer 203, third hidden layer 204, fourth hidden layer 205, fifth hidden layer 206 and self-encoder output layer 207;
自编码器输入层201、第一隐层202、第二隐层203、第三隐层204、第四隐层205、第五隐层206和自编码器输出层207依次连接,自编码器输入层201用于接收通气数据,自编码器输出层207为自编码器在训练时的输出层,第三隐层204用于输出特征数据。The self-encoder input layer 201, the first hidden layer 202, the second hidden layer 203, the third hidden layer 204, the fourth hidden layer 205, the fifth hidden layer 206 and the self-encoder output layer 207 are sequentially connected, and the self-encoder input The layer 201 is used to receive ventilation data, the autoencoder output layer 207 is the output layer of the autoencoder during training, and the third hidden layer 204 is used to output feature data.
步骤S13:将特征数据输入预设的卷积神经网络,以输出呼吸机的人机异步状态。Step S13: Input the feature data into the preset convolutional neural network to output the human-machine asynchronous state of the ventilator.
本实施例中,可将步骤S12中所提取的特征数据输入已预先完成相关训练的卷积神经网络中,以使卷积神经网络通过对特征数据的处理识别人机异步状态,进而可通过人机异步状态确定呼吸机的供气是否存在异步。人机异步状态至少包括双触发状态、无效吸气努力状态和正常状态,还可包括其它类型的人机异步状态,此处不作限定。举例说明:第一种情况,患者呼吸较为急促,呼吸机可能会连续捕捉到两次患者的吸气动作,进而将连续触发两次对患者进行机械通气的动作,从而造成过量供气的状况发生,此时的呼吸机就处于双触发状态;第二种情况,患者呼吸力度较弱,呼吸机可能始终或经常捕捉不到患者的吸气动作,进而无法触发对患者进行机械通气的动作,从而造成患者窒息的危险,此时的呼吸机就处于无效吸气努力状态;第三种情况,呼吸机正常在患者需要吸气时供气,在患者需要呼气时停止供气,此时的呼吸机就处于正常状态。本申请的机械通气人机异步检测方法可快速、准确识别出上述三种情况下的异常状态(双触发状态和无效吸气努力状态)或正常状态。In this embodiment, the feature data extracted in step S12 can be input into the convolutional neural network that has completed relevant training in advance, so that the convolutional neural network can identify the asynchronous state of man and machine through the processing of feature data, and then can pass human The Ventilator Asynchronous Status determines whether there is asynchronous air supply to the ventilator. The man-machine asynchronous state includes at least double-trigger state, invalid inspiratory effort state and normal state, and may also include other types of man-machine asynchronous states, which are not limited here. For example: In the first case, the patient’s breathing is relatively rapid, and the ventilator may capture the patient’s inspiratory movements twice in a row, which will then trigger the patient’s mechanical ventilation twice in a row, resulting in an oversupply situation. , the ventilator is in a dual-trigger state at this time; in the second case, the patient’s breathing force is weak, and the ventilator may always or often fail to capture the patient’s inspiratory action, and thus cannot trigger the patient’s mechanical ventilation action, thus In the third case, the ventilator normally supplies air when the patient needs to inhale, and stops supplying air when the patient needs to exhale. The machine is in normal condition. The man-machine asynchronous detection method for mechanical ventilation of the present application can quickly and accurately identify the abnormal state (double trigger state and invalid inspiratory effort state) or normal state in the above three situations.
可选的,如图3所示,图3是本申请的一维卷积神经网络的一实施例的结构示意图。Optionally, as shown in FIG. 3 , FIG. 3 is a schematic structural diagram of an embodiment of a one-dimensional convolutional neural network of the present application.
卷积神经网络为一维卷积神经网络30;The convolutional neural network is a one-dimensional convolutional neural network 30;
一维卷积神经网络30包括:一维卷积神经网络输入层301、第一一维卷积层302、第一最大池化层303、第二一维卷积层304、第二最大池化层305、第三一维卷积层306、第一全连接层307、第二全连接层308和一维卷积神经网络输出层309;One-dimensional convolutional neural network 30 includes: one-dimensional convolutional neural network input layer 301, first one-dimensional convolutional layer 302, first maximum pooling layer 303, second one-dimensional convolutional layer 304, second maximum pooling Layer 305, the third one-dimensional convolutional layer 306, the first fully connected layer 307, the second fully connected layer 308 and the one-dimensional convolutional neural network output layer 309;
一维卷积神经网络输入层301、第一一维卷积层302、第一最大池化层303、 第二一维卷积层304、第二最大池化层305、第三一维卷积层306、第一全连接层307、第二全连接层308和一维卷积神经网络输出层309依次连接,一维卷积神经网络输入层301用于接收特征数据,一维卷积神经网络输出层309用于输出人机异步状态。One-dimensional convolution neural network input layer 301, first one-dimensional convolution layer 302, first maximum pooling layer 303, second one-dimensional convolution layer 304, second maximum pooling layer 305, third one-dimensional convolution Layer 306, the first fully connected layer 307, the second fully connected layer 308 and the one-dimensional convolutional neural network output layer 309 are sequentially connected, the one-dimensional convolutional neural network input layer 301 is used to receive feature data, and the one-dimensional convolutional neural network The output layer 309 is used to output the human-machine asynchronous state.
可选的,如图4所示,图4是本申请的机械通气人机异步检测方法的另一实施例的流程示意图。本实施例呼吸监测方法具体还包括以下步骤:Optionally, as shown in FIG. 4 , FIG. 4 is a schematic flow chart of another embodiment of the method for detecting human-machine asynchrony in mechanical ventilation of the present application. The respiratory monitoring method of this embodiment specifically further includes the following steps:
步骤S21:获取训练数据。Step S21: Obtain training data.
本实施例中,可基于对真实的呼吸事件的了解,采用呼吸机与模拟肺,仿真模拟具有急性呼吸窘迫综合征(acute respiratory distress syndrome,ARDS)的患者在使用呼吸机时面对不同人机异步状态(至少包括:双触发状态、无效吸气努力状态和正常状态)时的呼吸事件,之后基于多个呼吸事件获取在呼吸机处于不同人机异步状态时的模拟通气数据,并将该不同呼吸事件下的模拟通气数据作为训练数据。In this embodiment, based on the understanding of real respiratory events, a ventilator and a simulated lung can be used to simulate patients with acute respiratory distress syndrome (ARDS) facing different man-machines when using a ventilator. Respiratory events in the asynchronous state (including at least: double-trigger state, invalid inspiratory effort state and normal state), and then obtain simulated ventilation data when the ventilator is in different man-machine asynchronous states based on multiple respiratory events, and use the different Simulated ventilation data under respiratory events were used as training data.
步骤S22:对训练数据进行预处理;其中,预处理至少包括对训练数据进行人机异步状态标注。Step S22: Perform preprocessing on the training data; wherein, the preprocessing includes at least marking the training data with man-machine asynchronous state.
步骤S23:将预处理之后的训练数据输入自编码器,以对自编码器进行训练。Step S23: Input the preprocessed training data into the autoencoder to train the autoencoder.
本实施例中,可先对训练数据进行预处理(至少包括对训练数据进行各训练数据所对应人机异步状态的标注),之后再基于预处理之后的训练数据对自编码器进行训练,并在训练完毕后以训练的自编码器的第三隐层(中间层)的输出数据作为通气数据的特征数据。In this embodiment, the training data can be preprocessed first (including at least marking the training data corresponding to the man-machine asynchronous state of each training data), and then the autoencoder is trained based on the preprocessed training data, and After the training is completed, the output data of the third hidden layer (middle layer) of the trained self-encoder is used as the feature data of the ventilation data.
可选的,如图4所示,图4是本申请的机械通气人机异步检测方法的另一实施例的流程示意图。步骤S22具体可包括:将训练数据划分为多个数据段,对每一数据段进行人机异步状态标注。Optionally, as shown in FIG. 4 , FIG. 4 is a schematic flow chart of another embodiment of the method for detecting human-machine asynchrony in mechanical ventilation of the present application. Step S22 may specifically include: dividing the training data into multiple data segments, and marking each data segment with a man-machine asynchronous state.
步骤S23具体可包括:分别将每一人机异步状态对应的数据输入自编码器,以对自编码器进行训练。Step S23 may specifically include: respectively inputting data corresponding to each man-machine asynchronous state into the autoencoder, so as to train the autoencoder.
进一步的,如图5所示,图5是图4所示机械通气人机异步检测方法中的步骤S22的具体流程示意图。步骤S22具体可包括以下步骤:Further, as shown in FIG. 5 , FIG. 5 is a schematic flow chart of step S22 in the method for detecting the asynchronous detection of man-machine in mechanical ventilation shown in FIG. 4 . Step S22 may specifically include the following steps:
步骤S221:将训练数据划分为多个数据段。Step S221: Divide the training data into multiple data segments.
步骤S222:对每一数据段进行采样点补齐,以使每一数据段的采样点数量 相同。Step S222: Completing the sampling points for each data segment, so that the number of sampling points in each data segment is the same.
步骤S223:利用每一数据段中各个采样点数据的均值和标准差,对每一数据段的数据进行标准化处理。Step S223: Standardize the data of each data segment by using the mean value and standard deviation of the data of each sampling point in each data segment.
步骤S224:对标准化处理之后的每一数据段进行人机异步状态标注。Step S224: Carry out man-machine asynchronous state labeling for each data segment after normalization processing.
本实施例中,上述采样点补齐可以是对每一段数据进行补零或截断,以使每一数据段的数量相同(长度相同),举例说明,可将每一数据段通过补零或删除过多部分的采样点的方式使其均具备100个采样点数据。In this embodiment, the filling of the above-mentioned sampling points may be to pad or truncate each piece of data so that the number of each data section is the same (same length). For example, each data section can be filled with zeros or deleted. The method of too many sampling points makes it have 100 sampling point data.
例如,在实际中,最长呼吸周期信号长度计算公式如下:For example, in practice, the calculation formula of the longest respiratory cycle signal length is as follows:
maxLen=max(len(P 1,P 2,…,P L)); maxLen=max(len(P 1 ,P 2 ,...,P L ));
L=len trainset+len testsetL=len trainset +len testset ;
式中,maxLen为最长呼吸周期信号长度,len trainset为训练数据的数据段数量,len testset为测试数据的数据段数量,P x为一训练数据或测试数据的数据段,测试数据用于对自编码器和卷积神经网络进行测试之用。 In the formula, maxLen is the longest respiratory cycle signal length, len trainset is the data segment quantity of training data, len testset is the data segment quantity of test data, P x is the data segment of a training data or test data, and test data is used for Autoencoders and Convolutional Neural Networks for testing purposes.
可基于上述最长呼吸周期信号长度计算公式计算出最长呼吸周期信号长度,若该最长呼吸周期信号长度为100,则可将每一数据段通过补零或删除过多部分的采样点的方式使其均具备100个采样点数据。The longest respiratory cycle signal length can be calculated based on the above-mentioned longest respiratory cycle signal length calculation formula. If the longest respiratory cycle signal length is 100, each data segment can be filled with zeros or deleted. The method makes it have 100 sampling point data.
在对每一数据段进行采样点补齐后再基于每一数据段中各个采样点数据的均值和标准差(或方差)分别对每一段数据段进行标准化处理,基于经标准化处理和标注划分的训练数据对自编码器和卷积神经网络进行训练,有利于进一步提高自编码器和卷积神经网络在进行特征提取和/或识别人机异步状态的效率和准确度。After completing the sampling points for each data segment, each data segment is standardized based on the mean value and standard deviation (or variance) of each sampling point data in each data segment. The training data trains the autoencoder and the convolutional neural network, which is conducive to further improving the efficiency and accuracy of the autoencoder and convolutional neural network in feature extraction and/or recognition of human-machine asynchronous states.
具体的,所述标准化处理的公式如下:Specifically, the formula of the normalization process is as follows:
Figure PCTCN2021137606-appb-000001
Figure PCTCN2021137606-appb-000001
式中,
Figure PCTCN2021137606-appb-000002
为标准化处理后的采样点数据,N x为标准化处理前的采样点数据,μ为该采样点数据所在数据段的采样点数据均值,σ为该采样点数据所在数据段的采样点数据标准差。
In the formula,
Figure PCTCN2021137606-appb-000002
is the sampling point data after normalization processing, N x is the sampling point data before normalization processing, μ is the mean value of the sampling point data in the data segment where the sampling point data is located, and σ is the standard deviation of the sampling point data in the data segment where the sampling point data is located .
在一实际应用场景中,训练数据和通气数据均可包括气流流速数据、气流通道压力数据和气流量数据三种类型的数据,可形成三维数据。例如,某次呼吸周期的气流流速数据的一数据段序列为F x=(f 1,f 2,…,f x),气流通道压力数据的一数据段序列为P x=(p 1,p 2,…,p x),气流量数据的一数据段序列为 V x=(v 1,v 2,…,v x)。那么,在对F x、P x、V x执行标准化后,上述标准化处理的公式中的N可指代F、P、V三者中的任一种。 In an actual application scenario, the training data and the ventilation data may include three types of data, namely air flow velocity data, air flow channel pressure data and air flow data, and may form three-dimensional data. For example, a sequence of data segments of the airflow velocity data of a breathing cycle is F x =(f 1 , f 2 ,...,f x ), and a sequence of data segments of airflow channel pressure data is P x =(p 1 ,p 2 ,...,p x ), a sequence of data segments of air flow data is V x =(v 1 ,v 2 ,...,v x ). Then, after normalization is performed on F x , P x , and V x , N in the formula of the above normalization process may refer to any one of F, P, and V.
自编码器可包括:自编码器输入层、第一隐层、第二隐层、第三隐层、第四隐层、第五隐层和自编码器输出层;自编码器输入层、第一隐层、第二隐层、第三隐层、第四隐层、第五隐层和自编码器输出层依次连接。其中,第一隐层、第二隐层、第三隐层、第四隐层、第五隐层的神经元数目分别是128、64、32、64、128,在训练自编码器时,将训练数据同时作为自编码器输入层的输入数据和自编码器输出层的输出数据,以进行训练。在实际使用自编码器时,可将第三隐层输出的数据作为自编码器基于通气数据所提取的特征数据,以提取作为三维数据的通气数据的特征,形成一维特征数据,实现了特征数据的提取及降维,有利于后续卷积神经网络对该特征数据的快速处理。Self-encoder may comprise: self-encoder input layer, first hidden layer, second hidden layer, third hidden layer, fourth hidden layer, fifth hidden layer and self-encoder output layer; self-encoder input layer, second hidden layer The first hidden layer, the second hidden layer, the third hidden layer, the fourth hidden layer, the fifth hidden layer and the output layer of the autoencoder are sequentially connected. Among them, the number of neurons in the first hidden layer, the second hidden layer, the third hidden layer, the fourth hidden layer, and the fifth hidden layer are 128, 64, 32, 64, and 128 respectively. When training the autoencoder, the The training data is used as the input data of the input layer of the autoencoder and the output data of the output layer of the autoencoder at the same time for training. When the autoencoder is actually used, the data output by the third hidden layer can be used as the feature data extracted by the autoencoder based on the ventilation data, so as to extract the characteristics of the ventilation data as three-dimensional data, form one-dimensional feature data, and realize the feature The extraction and dimensionality reduction of data is conducive to the rapid processing of the feature data by the subsequent convolutional neural network.
卷积神经网络为一维卷积神经网络;一维卷积神经网络包括:一维卷积神经网络输入层、第一一维卷积层、第一最大池化层、第二一维卷积层、第二最大池化层、第三一维卷积层、第一全连接层、第二全连接层和一维卷积神经网络输出层;一维卷积神经网络输入层、第一一维卷积层、第一最大池化层、第二一维卷积层、第二最大池化层、第三一维卷积层、第一全连接层、第二全连接层和一维卷积神经网络输出层依次连接,其中,在所述第一全连接层和所述第二全连接层之间还可包括一Dropout层,以降低卷积神经网络中过拟合的风险。在训练一维卷积神经网络时,可将自编码器基于训练数据提取的一维特征数据输入一维卷积神经网络输入层,并将该训练数据所对应的标注信息(用于标注该训练数据所对应的人机异步状态的信息)作为一维卷积神经网络输出层的输出,以进行训练。在实际使用一维卷积神经网络时,可采取与训练时类似的步骤,将自编码器基于通气数据提取的一维特征数据输入一维卷积神经网络输入层,以使一维卷积神经网络输出对应的人机异步状态(即与所获取的通气数据所对应的人机异步状态)。基于上述方式,在呼吸监测过程中采用一维卷积神经网络处理一维数据,可大大提高呼吸监测的效率。The convolutional neural network is a one-dimensional convolutional neural network; the one-dimensional convolutional neural network includes: a one-dimensional convolutional neural network input layer, a first one-dimensional convolution layer, a first maximum pooling layer, a second one-dimensional convolution layer, the second maximum pooling layer, the third one-dimensional convolutional layer, the first fully connected layer, the second fully connected layer and the output layer of the one-dimensional convolutional neural network; the input layer of the one-dimensional convolutional neural network, the first one 1D convolutional layer, 1st max pooling layer, 2nd 1D convolutional layer, 2nd max pooling layer, 3rd 1D convolutional layer, 1st fully connected layer, 2nd fully connected layer and 1D convolution The output layers of the convolutional neural network are sequentially connected, wherein a dropout layer may also be included between the first fully connected layer and the second fully connected layer to reduce the risk of overfitting in the convolutional neural network. When training a one-dimensional convolutional neural network, the one-dimensional feature data extracted by the autoencoder based on the training data can be input into the input layer of the one-dimensional convolutional neural network, and the label information corresponding to the training data (used to label the training The information of the human-machine asynchronous state corresponding to the data) is used as the output of the output layer of the one-dimensional convolutional neural network for training. When using the one-dimensional convolutional neural network in practice, similar steps can be taken during training, and the one-dimensional feature data extracted by the autoencoder based on the ventilation data can be input into the input layer of the one-dimensional convolutional neural network to make the one-dimensional convolutional neural network The network outputs the corresponding man-machine asynchronous state (that is, the man-machine asynchronous state corresponding to the acquired ventilation data). Based on the above method, using a one-dimensional convolutional neural network to process one-dimensional data in the process of respiratory monitoring can greatly improve the efficiency of respiratory monitoring.
如图6所示,图6是本申请的自编码器训练损失与训练迭代次数关系示意图。A为气流流速数据的训练损失曲线,B为气流通道压力数据的训练损失曲线,C为气流量数据的训练损失曲线。随着训练过程中的训练迭代次数的增长,自编码器的训练损失(train loss)越来越小,在训练迭代次数达到一百次以上 时,训练损失就已降至接近收敛值了,收敛速度较快。As shown in FIG. 6 , FIG. 6 is a schematic diagram of the relationship between the autoencoder training loss and the number of training iterations in the present application. A is the training loss curve of the airflow velocity data, B is the training loss curve of the airflow channel pressure data, and C is the training loss curve of the air flow data. As the number of training iterations in the training process increases, the training loss of the autoencoder becomes smaller and smaller. When the number of training iterations reaches more than one hundred times, the training loss has dropped to close to the convergence value, and the convergence Faster.
如图7所示,图7是本申请的机械通气人机异步检测方法的混淆矩阵结果示意图。可见,本申请的机械通气人机异步检测方法在经一定量训练数据的训练后,对于双触发状态或无效吸气努力状态的准确检测概率均为100%,而对于正常状态的准确检测概率为97%,有3%的几率会将正常状态识别为双触发状态,可见,本申请机械通气人机异步检测方法的准确率极高,且随训练数据的增加,该准确率仍能不断提高。As shown in FIG. 7 , FIG. 7 is a schematic diagram of the confusion matrix result of the human-machine asynchronous detection method for mechanical ventilation of the present application. It can be seen that the human-machine asynchronous detection method for mechanical ventilation of the present application has an accurate detection probability of 100% for the double-trigger state or the invalid inspiratory effort state after training with a certain amount of training data, and the accurate detection probability for the normal state is 97%, there is a 3% probability that the normal state will be identified as a double-trigger state. It can be seen that the accuracy rate of the human-machine asynchronous detection method for mechanical ventilation in this application is extremely high, and the accuracy rate can continue to improve with the increase of training data.
本申请提供的机械通气人机异步检测方法,通过获取呼吸机进行机械通气时的通气数据;将通气数据输入预设的自编码器,以提取通气数据的特征数据;将特征数据输入预设的卷积神经网络,以输出呼吸机的人机异步状态。本申请通过先基于预设的自编码器对通气数据的特征数据进行提取,再将该特征数据输入预设的卷积神经网络,以识别该通气数据所对应的人机异步状态,避免了人工提取特征或人工识别人机异步状态的步骤,降低了的人力资源的消耗,提高了机械通气人机异步检测方法的效率和准确度。The man-machine asynchronous detection method for mechanical ventilation provided by this application obtains the ventilation data when the ventilator performs mechanical ventilation; inputs the ventilation data into the preset autoencoder to extract the characteristic data of the ventilation data; and inputs the characteristic data into the preset Convolutional neural network to output the human-machine asynchronous state of the ventilator. This application first extracts the characteristic data of the ventilation data based on the preset autoencoder, and then inputs the characteristic data into the preset convolutional neural network to identify the man-machine asynchronous state corresponding to the ventilation data, avoiding artificial The steps of extracting features or manually identifying the man-machine asynchronous state reduce the consumption of human resources and improve the efficiency and accuracy of the man-machine asynchronous detection method for mechanical ventilation.
本申请进一步提出一种机械通气人机异步检测装置,如图8所示,图8是本申请的机械通气人机异步检测装置的一实施例的结构示意图。本实施例的机械通气人机异步检测装置80包括:处理器81、存储器82以及总线83。The present application further proposes a human-machine asynchronous detection device for mechanical ventilation, as shown in FIG. 8 , which is a schematic structural diagram of an embodiment of the human-computer asynchronous detection device for mechanical ventilation of the present application. The apparatus 80 for detecting human-machine asynchrony of mechanical ventilation in this embodiment includes: a processor 81 , a memory 82 and a bus 83 .
该处理器81、存储器82分别与总线83相连,该存储器82中存储有程序指令,处理器81用于执行程序指令以实现上述实施例中的机械通气人机异步检测方法。The processor 81 and the memory 82 are connected to the bus 83 respectively. The memory 82 stores program instructions, and the processor 81 is used to execute the program instructions to implement the method for detecting asynchronous mechanical ventilation in the above embodiments.
在本实施例中,处理器81还可以称为CPU(Central Processing Unit,中央处理单元)。处理器81可能是一种集成电路芯片,具有信号的处理能力。处理器81还可以是通用处理器、数字信号处理器(DSP)、专用集成电路(ASIC)、现场可编程门阵列(FPGA)或者其它可编程逻辑器件、分立门或者晶体管逻辑器件、分立硬件组件。通用处理器可以是微处理器或者该处理器81也可以是任何常规的处理器等。In this embodiment, the processor 81 may also be called a CPU (Central Processing Unit, central processing unit). The processor 81 may be an integrated circuit chip with signal processing capabilities. The processor 81 can also be a general-purpose processor, a digital signal processor (DSP), an application-specific integrated circuit (ASIC), a field-programmable gate array (FPGA) or other programmable logic devices, discrete gate or transistor logic devices, discrete hardware components . The general processor may be a microprocessor or the processor 81 may be any conventional processor or the like.
上述机械通气人机异步检测装置可以是独立于呼吸机以外的检测装置,也可以是呼吸机的一部分,此处不作限定。The asynchronous detection device for mechanical ventilation mentioned above may be a detection device independent of the ventilator, or a part of the ventilator, which is not limited here.
本申请提供的机械通气人机异步检测方法,通过获取呼吸机进行机械通气时的通气数据;将通气数据输入预设的自编码器,以提取通气数据的特征数据; 将特征数据输入预设的卷积神经网络,以输出呼吸机的人机异步状态。本申请通过先基于预设的自编码器对通气数据的特征数据进行提取,再将该特征数据输入预设的卷积神经网络,以识别该通气数据所对应的人机异步状态,避免了人工提取特征或人工识别人机异步状态的步骤,降低了的人力资源的消耗,提高了机械通气人机异步检测方法的效率和准确度。The human-machine asynchronous detection method of mechanical ventilation provided by this application obtains the ventilation data when the ventilator performs mechanical ventilation; inputs the ventilation data into the preset autoencoder to extract the characteristic data of the ventilation data; and inputs the characteristic data into the preset Convolutional neural network to output the human-machine asynchronous state of the ventilator. This application first extracts the characteristic data of the ventilation data based on the preset autoencoder, and then inputs the characteristic data into the preset convolutional neural network to identify the man-machine asynchronous state corresponding to the ventilation data, avoiding artificial The steps of extracting features or manually identifying the man-machine asynchronous state reduce the consumption of human resources and improve the efficiency and accuracy of the man-machine asynchronous detection method for mechanical ventilation.
本申请进一步提出一种计算机可读存储介质,如图9所示,图9是本申请的计算机可读存储介质的一实施例的结构示意图计算机可读存储介质90其上存储有程序指令91,程序指令91被处理器(图未示)执行时实现上述实施例中的机械通气人机异步检测方法。The present application further proposes a computer-readable storage medium, as shown in FIG. 9 , which is a structural schematic diagram of an embodiment of the computer-readable storage medium of the present application. The computer-readable storage medium 90 stores program instructions 91 thereon, When the program instruction 91 is executed by the processor (not shown in the figure), the method for detecting the asynchronous detection of mechanical ventilation in the above-mentioned embodiments is realized.
本实施例计算机可读存储介质90可以是但不局限于U盘、SD卡、PD光驱、移动硬盘、大容量软驱、闪存、多媒体记忆卡、服务器等。The computer-readable storage medium 90 in this embodiment may be, but not limited to, a USB flash drive, an SD card, a PD optical drive, a mobile hard disk, a large-capacity floppy drive, a flash memory, a multimedia memory card, a server, and the like.
本申请提供的机械通气人机异步检测方法,通过获取呼吸机进行机械通气时的通气数据;将通气数据输入预设的自编码器,以提取通气数据的特征数据;将特征数据输入预设的卷积神经网络,以输出呼吸机的人机异步状态。本申请通过先基于预设的自编码器对通气数据的特征数据进行提取,再将该特征数据输入预设的卷积神经网络,以识别该通气数据所对应的人机异步状态,避免了人工提取特征或人工识别人机异步状态的步骤,降低了的人力资源的消耗,提高了机械通气人机异步检测方法的效率和准确度。The man-machine asynchronous detection method for mechanical ventilation provided by this application obtains the ventilation data when the ventilator performs mechanical ventilation; inputs the ventilation data into the preset autoencoder to extract the characteristic data of the ventilation data; and inputs the characteristic data into the preset Convolutional neural network to output the human-machine asynchronous state of the ventilator. This application first extracts the characteristic data of the ventilation data based on the preset autoencoder, and then inputs the characteristic data into the preset convolutional neural network to identify the man-machine asynchronous state corresponding to the ventilation data, avoiding artificial The steps of extracting features or manually identifying the man-machine asynchronous state reduce the consumption of human resources and improve the efficiency and accuracy of the man-machine asynchronous detection method for mechanical ventilation.
在本申请的描述中,参考术语“一个实施例”、“一些实施例”、“示例”、“具体示例”、或“一些示例”等的描述意指结合该实施例或示例描述的具体特征、结构、材料或者特点包含于本申请的至少一个实施例或示例中。在本说明书中,对上述术语的示意性表述不必须针对的是相同的实施例或示例。而且,描述的具体特征、结构、材料或者特点可以在任一个或多个实施例或示例中以合适的方式结合。此外,在不相互矛盾的情况下,本领域的技术人员可以将本说明书中描述的不同实施例或示例以及不同实施例或示例的特征进行结合和组合。In the description of this application, reference to the terms "one embodiment," "some embodiments," "example," "specific examples," or "some examples" means that specific features described in connection with that embodiment or example , structure, material or characteristic is included in at least one embodiment or example of the present application. In this specification, the schematic representations of the above terms are not necessarily directed to the same embodiment or example. Furthermore, the described specific features, structures, materials or characteristics may be combined in any suitable manner in any one or more embodiments or examples. In addition, those skilled in the art can combine and combine different embodiments or examples and features of different embodiments or examples described in this specification without conflicting with each other.
此外,术语“第一”、“第二”仅用于描述目的,而不能理解为指示或暗示相对重要性或者隐含指明所指示的技术特征的数量。由此,限定有“第一”、“第二”的特征可以明示或者隐含地包括至少一个该特征。在本申请的描述中,“多个”的含义是至少两个,例如两个,三个等,除非另有明确具体的限定。In addition, the terms "first" and "second" are used for descriptive purposes only, and cannot be interpreted as indicating or implying relative importance or implicitly specifying the quantity of indicated technical features. Thus, the features defined as "first" and "second" may explicitly or implicitly include at least one of these features. In the description of the present application, "plurality" means at least two, such as two, three, etc., unless otherwise specifically defined.
流程图中或在此以其他方式描述的任何过程或方法描述可以被理解为,表 示包括一个或更多个用于实现特定逻辑功能或过程的步骤的可执行指令的代码的模块、片段或部分,并且本申请的优选实施方式的范围包括另外的实现,其中可以不按所示出或讨论的顺序,包括根据所涉及的功能按基本同时的方式或按相反的顺序,来执行功能,这应被本申请的实施例所属技术领域的技术人员所理解。Any process or method descriptions in flowcharts or otherwise described herein may be understood to represent modules, segments or portions of code comprising one or more executable instructions for implementing specific logical functions or steps of the process , and the scope of preferred embodiments of the present application includes additional implementations in which functions may be performed out of the order shown or discussed, including in substantially simultaneous fashion or in reverse order depending on the functions involved, which shall It should be understood by those skilled in the art to which the embodiments of the present application belong.
在流程图中表示或在此以其他方式描述的逻辑和/或步骤,例如,可以被认为是用于实现逻辑功能的可执行指令的定序列表,可以具体实现在任何计算机可读介质中,以供指令执行系统、装置或设备(可以是个人计算机,服务器,网络设备或其他可以从指令执行系统、装置或设备取指令并执行指令的系统)使用,或结合这些指令执行系统、装置或设备而使用。就本说明书而言,"计算机可读介质"可以是任何可以包含、存储、通信、传播或传输程序以供指令执行系统、装置或设备或结合这些指令执行系统、装置或设备而使用的装置。计算机可读介质的更具体的示例(非穷尽性列表)包括以下:具有一个或多个布线的电连接部(电子装置),便携式计算机盘盒(磁装置),随机存取存储器(RAM),只读存储器(ROM),可擦除可编辑只读存储器(EPROM或闪速存储器),光纤装置,以及便携式光盘只读存储器(CDROM)。另外,计算机可读介质甚至可以是可在其上打印所述程序的纸或其他合适的介质,因为可以例如通过对纸或其他介质进行光学扫描,接着进行编辑、解译或必要时以其他合适方式进行处理来以电子方式获得所述程序,然后将其存储在计算机存储器中。The logic and/or steps represented in the flowcharts or otherwise described herein, for example, can be considered as a sequenced listing of executable instructions for implementing logical functions, can be embodied in any computer-readable medium, For the use of instruction execution systems, devices or equipment (which may be personal computers, servers, network equipment or other systems that can fetch instructions from instruction execution systems, devices or devices and execute instructions), or in combination with these instruction execution systems, devices or devices And use. For the purposes of this specification, a "computer-readable medium" may be any device that can contain, store, communicate, propagate or transmit a program for use in or in conjunction with an instruction execution system, device or device. More specific examples (non-exhaustive list) of computer-readable media include the following: electrical connection with one or more wires (electronic device), portable computer disk case (magnetic device), random access memory (RAM), Read Only Memory (ROM), Erasable and Editable Read Only Memory (EPROM or Flash Memory), Fiber Optic Devices, and Portable Compact Disc Read Only Memory (CDROM). In addition, the computer-readable medium may even be paper or other suitable medium on which the program can be printed, since the program can be read, for example, by optically scanning the paper or other medium, followed by editing, interpretation or other suitable processing if necessary. The program is processed electronically and stored in computer memory.
以上所述仅为本申请的实施方式,并非因此限制本申请的专利范围,凡是利用本申请说明书及附图内容所作的等效结构或等效流程变换,或直接或间接运用在其他相关的技术领域,均同理包括在本申请的专利保护范围内。The above is only the implementation of the application, and does not limit the patent scope of the application. Any equivalent structure or equivalent process conversion made by using the specification and drawings of the application, or directly or indirectly used in other related technologies fields, are all included in the scope of patent protection of this application in the same way.

Claims (10)

  1. 一种机械通气人机异步检测方法,其特征在于,包括:A mechanical ventilation man-machine asynchronous detection method, characterized in that it includes:
    获取呼吸机进行机械通气时的通气数据;Obtain the ventilation data when the ventilator is performing mechanical ventilation;
    将所述通气数据输入预设的自编码器,以提取所述通气数据的特征数据;inputting the ventilation data into a preset autoencoder to extract characteristic data of the ventilation data;
    将所述特征数据输入预设的卷积神经网络,以输出所述呼吸机的人机异步状态。The feature data is input into a preset convolutional neural network to output the man-machine asynchronous state of the ventilator.
  2. 根据权利要求1所述的机械通气人机异步检测方法,其特征在于,The mechanical ventilation human-machine asynchronous detection method according to claim 1, characterized in that,
    所述通气数据至少包括气流流速数据、气流通道压力数据和气流量数据中的一种。The ventilation data includes at least one of air flow velocity data, air flow channel pressure data and air flow data.
  3. 根据权利要求1所述的机械通气人机异步检测方法,其特征在于,The mechanical ventilation human-machine asynchronous detection method according to claim 1, characterized in that,
    所述人机异步状态至少包括双触发状态、无效吸气努力状态和正常状态中的一种。The man-machine asynchronous state includes at least one of a double trigger state, an invalid inspiratory effort state and a normal state.
  4. 根据权利要求1所述的机械通气人机异步检测方法,其特征在于,The mechanical ventilation human-machine asynchronous detection method according to claim 1, characterized in that,
    所述方法还包括:The method also includes:
    获取训练数据;get training data;
    对所述训练数据进行预处理;其中,所述预处理至少包括对所述训练数据进行人机异步状态标注;Preprocessing the training data; wherein, the preprocessing includes at least marking the training data with man-machine asynchronous state;
    将预处理之后的所述训练数据输入所述自编码器,以对所述自编码器进行训练。Inputting the preprocessed training data into the autoencoder to train the autoencoder.
  5. 根据权利要求4所述的机械通气人机异步检测方法,其特征在于,The mechanical ventilation human-machine asynchronous detection method according to claim 4, characterized in that,
    所述对所述训练数据进行预处理,包括:The preprocessing of the training data includes:
    将所述训练数据划分为多个数据段;dividing the training data into a plurality of data segments;
    对每一所述数据段进行人机异步状态标注;以及Carrying out man-machine asynchronous status labeling for each of the data segments; and
    所述将预处理之后的所述训练数据输入所述自编码器,以对所述自编码器进行训练,包括:The step of inputting the preprocessed training data into the autoencoder to train the autoencoder includes:
    分别将每一人机异步状态对应的数据输入所述自编码器,以对所述自编码器进行训练。The data corresponding to each man-machine asynchronous state is input to the autoencoder to train the autoencoder.
  6. 根据权利要求5所述的机械通气人机异步检测方法,其特征在于,The human-machine asynchronous detection method for mechanical ventilation according to claim 5, characterized in that,
    所述将所述训练数据划分为多个数据段之后,还包括:After said dividing the training data into multiple data segments, it also includes:
    对每一所述数据段进行采样点补齐,以使每一所述数据段的采样点数量相同;Completing the sampling points for each of the data segments, so that the number of sampling points for each of the data segments is the same;
    利用每一所述数据段中各个采样点数据的均值和标准差,对每一所述数据段的数据进行标准化处理。Using the mean value and standard deviation of the data of each sampling point in each of the data segments, the data of each of the data segments is standardized.
  7. 根据权利要求1至6任一项所述的机械通气人机异步检测方法,其特征在于,所述自编码器包括:自编码器输入层、第一隐层、第二隐层、第三隐层、第四隐层、第五隐层和自编码器输出层;The human-machine asynchronous detection method according to any one of claims 1 to 6, wherein the autoencoder includes: an autoencoder input layer, a first hidden layer, a second hidden layer, and a third hidden layer. layer, the fourth hidden layer, the fifth hidden layer and the autoencoder output layer;
    所述自编码器输入层、所述第一隐层、所述第二隐层、所述第三隐层、所述第四隐层、所述第五隐层和所述自编码器输出层依次连接,所述自编码器输入层用于接收所述通气数据,所述自编码器输出层为所述自编码器在训练时的输出层,所述第三隐层用于输出所述特征数据。The autoencoder input layer, the first hidden layer, the second hidden layer, the third hidden layer, the fourth hidden layer, the fifth hidden layer and the autoencoder output layer connected in sequence, the autoencoder input layer is used to receive the ventilation data, the autoencoder output layer is the output layer of the autoencoder during training, and the third hidden layer is used to output the feature data.
  8. 根据权利要求1至6任一项所述的机械通气人机异步检测方法,其特征在于,所述卷积神经网络为一维卷积神经网络;The human-machine asynchronous detection method for mechanical ventilation according to any one of claims 1 to 6, wherein the convolutional neural network is a one-dimensional convolutional neural network;
    所述一维卷积神经网络包括:一维卷积神经网络输入层、第一一维卷积层、第一最大池化层、第二一维卷积层、第二最大池化层、第三一维卷积层、第一全连接层、第二全连接层和一维卷积神经网络输出层;The one-dimensional convolutional neural network comprises: one-dimensional convolutional neural network input layer, the first one-dimensional convolutional layer, the first maximum pooling layer, the second one-dimensional convolutional layer, the second maximum pooling layer, the first Three one-dimensional convolutional layer, first fully connected layer, second fully connected layer and one-dimensional convolutional neural network output layer;
    所述一维卷积神经网络输入层、所述第一一维卷积层、所述第一最大池化层、所述第二一维卷积层、所述第二最大池化层、所述第三一维卷积层、所述第一全连接层、所述第二全连接层和所述一维卷积神经网络输出层依次连接,所述一维卷积神经网络输入层用于接收所述特征数据,所述一维卷积神经网络输出层用于输出人机异步状态。The one-dimensional convolutional neural network input layer, the first one-dimensional convolutional layer, the first maximum pooling layer, the second one-dimensional convolutional layer, the second maximum pooling layer, the The third one-dimensional convolutional layer, the first fully connected layer, the second fully connected layer and the one-dimensional convolutional neural network output layer are sequentially connected, and the one-dimensional convolutional neural network input layer is used for The feature data is received, and the output layer of the one-dimensional convolutional neural network is used to output the asynchronous state of man-machine.
  9. 一种机械通气人机异步检测装置,其特征在于,包括:存储器和处理器;A mechanical ventilation human-machine asynchronous detection device, characterized in that it includes: a memory and a processor;
    所述存储器用于存储程序指令,所述处理器用于执行所述程序指令以实现如权利要求1至8任一项所述方法。The memory is used to store program instructions, and the processor is used to execute the program instructions to implement the method according to any one of claims 1 to 8.
  10. 一种计算机可读存储介质,其特征在于,所述计算机可读存储介质存储有程序指令,所述程序指令被处理器执行时实现如权利要求1至8任一项所述方法。A computer-readable storage medium, wherein the computer-readable storage medium stores program instructions, and when the program instructions are executed by a processor, the method according to any one of claims 1 to 8 is implemented.
PCT/CN2021/137606 2021-05-20 2021-12-13 Mechanical ventilation man-machine asynchronous detection method and apparatus, and computer-readable storage medium WO2022242123A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN202110553820.3 2021-05-20
CN202110553820.3A CN113521460B (en) 2021-05-20 2021-05-20 Mechanical ventilation man-machine asynchronous detection method, device and computer readable storage medium

Publications (1)

Publication Number Publication Date
WO2022242123A1 true WO2022242123A1 (en) 2022-11-24

Family

ID=78094653

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2021/137606 WO2022242123A1 (en) 2021-05-20 2021-12-13 Mechanical ventilation man-machine asynchronous detection method and apparatus, and computer-readable storage medium

Country Status (2)

Country Link
CN (1) CN113521460B (en)
WO (1) WO2022242123A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113521460B (en) * 2021-05-20 2024-02-23 深圳先进技术研究院 Mechanical ventilation man-machine asynchronous detection method, device and computer readable storage medium
CN113539398A (en) * 2021-06-25 2021-10-22 中国科学院深圳先进技术研究院 Breathing machine man-machine asynchronous classification method, system, terminal and storage medium
CN114191665A (en) * 2021-12-01 2022-03-18 中国科学院深圳先进技术研究院 Method and device for classifying man-machine asynchronous phenomena in mechanical ventilation process
CN114712643B (en) * 2022-02-21 2023-07-18 深圳先进技术研究院 Mechanical ventilation man-machine asynchronous detection method and device based on graph neural network
CN115814222B (en) * 2023-01-17 2023-04-14 中国科学院深圳先进技术研究院 Man-machine asynchronous waveform identification method under hybrid mechanical ventilation mode and related equipment

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102961125A (en) * 2006-06-05 2013-03-13 佛罗里达大学研究基金公司 Ventilator monitor system and method of using same
CN105125215A (en) * 2015-10-08 2015-12-09 湖南明康中锦医疗科技发展有限公司 Neural network based breathing machine state analytic method and device
CN109480783A (en) * 2018-12-20 2019-03-19 深圳和而泰智能控制股份有限公司 A kind of apnea detection method, apparatus and calculate equipment
CN109498952A (en) * 2018-11-30 2019-03-22 深圳市科曼医疗设备有限公司 Ventilator proportioning valve flow control methods, device, computer equipment
CN109893732A (en) * 2019-02-28 2019-06-18 杭州智瑞思科技有限公司 A kind of mechanical ventilation patient-ventilator asynchrony detection method based on Recognition with Recurrent Neural Network
CN110251137A (en) * 2019-06-05 2019-09-20 长沙湖湘医疗器械有限公司 A kind of sleep detection method for noninvasive ventilator and the ventilator using this method
CN113521460A (en) * 2021-05-20 2021-10-22 深圳先进技术研究院 Mechanical ventilation man-machine asynchronous detection method and device and computer readable storage medium

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102961125A (en) * 2006-06-05 2013-03-13 佛罗里达大学研究基金公司 Ventilator monitor system and method of using same
CN105125215A (en) * 2015-10-08 2015-12-09 湖南明康中锦医疗科技发展有限公司 Neural network based breathing machine state analytic method and device
CN109498952A (en) * 2018-11-30 2019-03-22 深圳市科曼医疗设备有限公司 Ventilator proportioning valve flow control methods, device, computer equipment
CN109480783A (en) * 2018-12-20 2019-03-19 深圳和而泰智能控制股份有限公司 A kind of apnea detection method, apparatus and calculate equipment
CN109893732A (en) * 2019-02-28 2019-06-18 杭州智瑞思科技有限公司 A kind of mechanical ventilation patient-ventilator asynchrony detection method based on Recognition with Recurrent Neural Network
CN110251137A (en) * 2019-06-05 2019-09-20 长沙湖湘医疗器械有限公司 A kind of sleep detection method for noninvasive ventilator and the ventilator using this method
CN113521460A (en) * 2021-05-20 2021-10-22 深圳先进技术研究院 Mechanical ventilation man-machine asynchronous detection method and device and computer readable storage medium

Also Published As

Publication number Publication date
CN113521460B (en) 2024-02-23
CN113521460A (en) 2021-10-22

Similar Documents

Publication Publication Date Title
WO2022242123A1 (en) Mechanical ventilation man-machine asynchronous detection method and apparatus, and computer-readable storage medium
CN109893732B (en) Mechanical ventilation man-machine asynchrony detection method based on recurrent neural network
Shi et al. Theory and Application of Audio‐Based Assessment of Cough
WO2022267381A1 (en) Patient-ventilator asynchrony classification method and system, terminal and storage medium
CN108399951B (en) Breathing machine-related pneumonia decision-making assisting method, device, equipment and medium
CN112507701B (en) Identification method, device, equipment and storage medium of medical data to be corrected
WO2022267382A1 (en) Human-machine asynchronous classification method and system for ventilator, terminal and storage medium
CN111563451B (en) Mechanical ventilation ineffective inhalation effort identification method based on multi-scale wavelet characteristics
Zulfiqar et al. Abnormal respiratory sounds classification using deep CNN through artificial noise addition
CN110162779A (en) Appraisal procedure, device and the equipment of quality of case history
CN111738305B (en) Mechanical ventilation man-machine asynchronous rapid identification method based on DBA-DTW-KNN
CN113642512B (en) Breathing machine asynchronous detection method, device, equipment and storage medium
CN109745011A (en) User's sleep-respiratory risk monitoring and control method, terminal and computer-readable medium
Mahmoudi et al. Sensor-based system for automatic cough detection and classification
WO2023097780A1 (en) Classification method and device for classifying patient‑ventilator asynchrony phenomenon in mechanical ventilation process
CN111653273A (en) Out-hospital pneumonia preliminary identification method based on smart phone
El-Badawy et al. An effective machine learning approach for classifying artefact-free and distorted capnogram segments using simple time-domain features
CN113941061B (en) Man-machine asynchronous identification method, system, terminal and storage medium
CN114534041A (en) Respiratory waveform classification model training method and device for detecting man-machine ventilation asynchronism
CN111080625B (en) Training method and training device for lung image strip and rope detection model
CN113936663A (en) Method for detecting difficult airway, electronic device and storage medium thereof
CN113689948A (en) Man-machine asynchronous detection method and device for mechanical ventilation of breathing machine and related equipment
WO2023060478A1 (en) Human-machine asynchronization identification method and system, and terminal and storage medium
Shi et al. A two stage recognition method of lung sounds based on multiple features
CN113730755B (en) Mechanical ventilation man-machine asynchronous detection and recognition method based on attention mechanism

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 21940566

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 21940566

Country of ref document: EP

Kind code of ref document: A1