WO2020258338A1 - Gas concentration measurement method and apparatus, medical ventilation device, and storage medium - Google Patents

Abstract

Disclosed is a gas concentration measurement method, applied to a medical ventilation device. The method comprises: during a ventilation process, inhibiting gas delivery of a medical ventilation device within a preset time period and according to a preset control mode (S201); and measuring a target gas concentration within the preset time period, wherein the target gas concentration is the concentration of any one gas composition in gas exhaled by a patient (S202).

Description

Method and device for measuring gas concentration, medical ventilation equipment, and storage medium Technical field

The embodiments of the present invention relate to the technical field of medical devices, and in particular to a gas measurement method and device, medical ventilation equipment, and storage media.

Background technique

Medical ventilation equipment such as ventilators and anesthesia machines need to measure the patient’s end-tidal carbon dioxide concentration in the process of mechanically ventilating the patient to help doctors analyze the patient’s ventilation status and determine whether the patient has hypercapnia or hypocapnia disease.

However, there is currently no method that can accurately measure the end-tidal carbon dioxide concentration.

Summary of the invention

In order to solve the above technical problems, the embodiments of the present invention expect to provide a gas concentration measurement method and device, medical ventilation equipment, and storage medium, which can reduce or eliminate fresh gas by inhibiting gas delivery for a period of time when ventilating a patient Dilution of the patient's exhaled air to accurately measure the target gas concentration in the patient's exhaled air.

The technical solutions of the embodiments of the present invention can be implemented as follows:

The embodiment of the present invention provides a gas concentration measurement method, which is applied to medical ventilation equipment, and the method includes:

In the process of ventilation, the medical ventilation equipment is inhibited from delivering gas within a preset time period according to a preset control method;

The target gas concentration is measured within a preset time period; the target gas concentration is the concentration of any gas component in the patient's exhaled air.

In the above solution, the preset control method is to reduce the air flow or stop the air flow.

In the above solution, the step of inhibiting the medical ventilation device from performing gas delivery within a preset time period according to a preset control method includes:

Obtain the preset suppression period;

According to the preset suppression period, the medical ventilation device is periodically suppressed from performing gas delivery in a preset time period according to the preset control mode.

In the above solution, the step of inhibiting the medical ventilation device from performing gas delivery within a preset time period according to a preset control method includes:

The trigger instruction is received, and the medical ventilation device is inhibited from performing gas delivery in a preset time period according to the preset control mode according to the trigger instruction.

In the above solution, before performing the step of inhibiting the medical ventilation device from performing gas delivery within a preset time period according to the preset control mode, the method further includes:

Obtain the physiological parameters of the patient;

If the physiological parameters of the patient indicate that the patient is in a stable state, the step of inhibiting the medical ventilation device from performing gas delivery within the preset time period according to the preset control mode is executed.

In the above solution, when performing the step of inhibiting the medical ventilation device from performing gas delivery within a preset time period according to the preset control mode, the method further includes:

Obtain the physiological parameters of the patient;

If the patient’s physiological parameters indicate that the patient is in an abnormal state, stop performing the steps of inhibiting the medical ventilation device from delivering gas within a preset time period in accordance with the preset control method, and control the medical ventilation device to perform ventilation and/or output according to the preset ventilation mode The patient is abnormal.

In the above solution, the step of measuring the target gas concentration within a preset time period includes:

The measurement of the target gas concentration is started at a time that is the preset time interval from the start time of the preset time period.

In the above solution, the step of measuring the target gas concentration within a preset time period includes:

If the target gas concentration measured within the preset time period changes regularly, stop performing the steps of inhibiting the medical ventilation device from performing gas delivery within the preset time period according to the preset control method, and control the medical ventilation device to perform according to the preset ventilation mode Ventilation.

In the above solution, when performing the step of inhibiting gas delivery within a preset time period according to a preset control method, the method further includes:

If a stop instruction is received, stop performing the step of inhibiting the medical ventilator from performing gas delivery within a preset time period according to the preset control mode, and control the medical ventilator to ventilate according to the preset ventilation mode.

In the above solution, after performing the step of inhibiting the medical ventilation device from performing gas delivery within a preset time period according to a preset control mode, the method further includes:

Control the medical ventilation equipment to ventilate according to the preset ventilation mode.

In the above solution, after performing the step of measuring the target gas concentration within a preset time period, the method further includes:

Output the measured target gas concentration and/or waveform.

In the above solution, before performing the step of inhibiting the medical ventilation device from performing gas delivery within a preset time period according to the preset control mode, the method further includes:

The patient is ventilated with oxygen.

In the above solution, when performing the step of measuring the target gas concentration within a preset time period, the method further includes:

Get the current air flow rate.

In the above solution, after performing the step of measuring the target gas concentration within a preset time period, the method further includes:

The measured target gas concentration is compensated according to the current gas flow rate.

In the above solution, when performing the step of measuring the target gas concentration within a preset time period, the method further includes:

Obtain the physiological parameters of the patient;

According to the patient's physiological signs data, determine whether the measured target gas concentration is abnormal.

In the above solution, when performing the step of inhibiting the medical ventilation device from performing gas delivery within a preset time period according to the preset control mode, the method further includes:

Output at least one of the relevant parameters corresponding to the preset control mode, the preset time period, the patient's physiological sign parameters and/or waveforms acquired during the preset time period, and the preset threshold corresponding to the patient's physiological sign parameters.

The embodiment of the present invention provides a gas concentration measuring device, which includes:

The control module, during the ventilation process, inhibits the medical ventilation equipment from delivering gas within a preset time period according to a preset control method;

The measurement module measures the concentration of the target gas within a preset time period; the target gas concentration is the concentration of any gas component in the patient's exhaled air.

In the above device, the preset control method is to reduce the air flow or stop the air flow.

In the above-mentioned device, the step of the control module inhibiting the medical ventilation equipment from performing gas delivery within a preset time period according to a preset control mode includes:

Obtain a preset suppression period; according to the preset suppression period, periodically and according to a preset control mode, the medical ventilation device is inhibited from gas delivery within a preset time period.

In the above-mentioned device, the step of the control module inhibiting the medical ventilation equipment from performing gas delivery within a preset time period according to a preset control mode includes:

The trigger instruction is received, and the medical ventilation device is inhibited from performing gas delivery in a preset time period according to the preset control mode according to the trigger instruction.

In the above-mentioned device, the control module obtains the patient's physiological parameters before performing the step of inhibiting the medical ventilation device from delivering gas within a preset time period according to the preset control mode; if the patient's physiological parameters indicate that the patient is in a stable state, Perform the step of inhibiting the medical ventilation device from performing gas delivery within a preset time period according to a preset control method.

In the above device, the control module obtains the patient's physiological parameters when performing the step of inhibiting the medical ventilation equipment from delivering gas within a preset period of time according to the preset control mode; if the patient's physiological parameters indicate that the patient is in an abnormal state, stop The step of inhibiting the medical ventilation device from performing gas delivery within a preset time period according to a preset control mode, and controlling the medical ventilation device to perform ventilation according to a preset ventilation mode and/or output a patient abnormality prompt.

In the above device, the measurement module starts to measure the target gas concentration at a time that is a preset time interval from the start time of the preset time period.

In the above device, if the target gas concentration measured by the measurement module within a preset time period changes regularly, the control module stops inhibiting the medical ventilation device from performing gas delivery, and controls the medical ventilation device to ventilate according to the preset ventilation mode.

In the above device, when the control module executes the step of inhibiting gas delivery within a preset time period according to the preset control method, if a stop instruction is received, it stops executing the step of inhibiting medical ventilation within the preset time period according to the preset control method The device performs the gas delivery step, and controls the medical ventilation device to ventilate according to the preset ventilation mode.

In the above-mentioned device, the control module controls the medical ventilation device to ventilate according to the preset ventilation mode after performing the step of inhibiting the medical ventilation device from performing gas delivery within a preset time period according to the preset control mode.

In the above device, the measurement module outputs the measured target gas concentration and/or waveform after performing the step of measuring the target gas concentration within a preset time period.

In the above device, the control module performs oxygen-enhancing ventilation on the patient before performing the step of inhibiting the medical ventilation device from delivering gas within a preset time period according to the preset control mode.

In the above device, the measurement module obtains the current gas flow rate when performing the step of measuring the target gas concentration within a preset time period. .

In the above-mentioned device, after the measurement module executes the step of measuring the target gas concentration within the preset time period, it compensates for the measured target gas concentration according to the current gas flow rate.

In the above-mentioned device, the measurement module also obtains the patient's physiological sign parameters when performing the step of measuring the target gas concentration within a preset time period; and judges whether the measured target gas concentration is abnormal according to the patient's physiological sign parameters.

The embodiment of the present invention provides a medical ventilation device including the above gas concentration measurement device, including a gas source, a breathing tube, and a display;

Gas source, which provides gas during ventilation;

The breathing circuit is connected to the air source to provide a breathing path during ventilation;

The gas concentration measuring device is connected with the breathing tube, gas source and display;

The gas concentration measuring device measures the target gas concentration during ventilation.

An embodiment of the present invention provides a computer-readable storage medium, which is characterized in that the computer-readable storage medium stores a gas concentration measurement program, and the gas concentration measurement program can be executed by a processor to implement the above-mentioned gas concentration measurement method.

It can be seen that, in the technical solution of the embodiment of the present invention, during the ventilation process, the medical ventilation device is inhibited from performing gas delivery within a preset time period according to a preset control mode; the target gas concentration is measured within the preset time period; Among them, the target gas concentration is the concentration of any gas component in the patient's breath. Through the technical solution of the embodiment of the present invention, the target gas concentration in the patient's exhaled air can be accurately measured when the patient is ventilated.

Description of the drawings

FIG. 1 is a schematic structural diagram of a gas concentration measurement device provided by an embodiment of the present invention;

2 is a schematic flowchart of a gas concentration measurement method provided by an embodiment of the present invention;

FIG. 3 is a schematic diagram of changes in airway pressure when a medical ventilation device for suppressing ventilation is provided by an embodiment of the present invention;

FIG. 4 is a schematic diagram of a change in air delivery flow rate when a medical ventilation device is suppressed to perform ventilation according to an embodiment of the present invention;

5 is a schematic diagram of a change in carbon dioxide concentration when a medical ventilation device is suppressed during ventilation provided by an embodiment of the present invention;

Fig. 6 is a schematic structural diagram of a medical ventilation device provided by an embodiment of the present invention.

Detailed ways

In order to understand the features and technical content of the embodiments of the present invention in more detail, the implementation of the embodiments of the present invention will be described in detail below with reference to the accompanying drawings. The attached drawings are for reference and description purposes only, and are not used to limit the embodiments of the present invention.

The embodiment of the present invention provides a gas concentration measurement method, which is applied to medical ventilation equipment such as a ventilator. It should be noted that, in the embodiment of the present invention, the gas concentration measurement method is executed by the gas concentration measurement device. Fig. 1 is a schematic structural diagram of a gas concentration measuring device provided by an embodiment of the present invention. As shown in FIG. 1, the gas concentration measurement device includes: a control module 101 and a measurement module 102. The gas concentration measurement method in the present invention will be described in detail below based on the gas concentration measurement device.

FIG. 2 is a schematic flowchart of a method for measuring gas concentration according to an embodiment of the present invention. As shown in Figure 2, the gas concentration measurement method mainly includes the following steps:

S201. In the process of ventilation, inhibit the medical ventilation device from performing gas delivery within a preset time period according to a preset control mode.

In the embodiment of the present invention, the control module 101 of the gas concentration measurement device may inhibit the medical ventilation device from performing gas delivery within a preset time period according to a preset control method during the ventilation process of the medical ventilation device.

It should be noted that, in the embodiment of the present invention, the medical ventilation equipment can be a ventilator, an anesthesia machine and other medical equipment with ventilation function. In addition, the ventilation mode of the medical ventilation equipment can be invasive ventilation, non-invasive ventilation, oxygen therapy , And any one of oxygen inhalation through the nasal catheter, the specific medical ventilation equipment and ventilation method are not limited in the embodiment of the present invention.

It should be noted that, in the embodiment of the present invention, the preset control method is to reduce the air flow or stop the air flow. The specific preset control method is not limited in the embodiment of the present invention.

It is understandable that, in the embodiment of the present invention, other concentration measuring devices are preset with a preset time period. When the control module 101 reduces the gas flow or stops the gas flow to inhibit the medical ventilator from performing gas delivery, The time when the suppression is executed is the preset time period. The specific preset time period is not limited in the embodiment of the present invention.

Exemplarily, in the embodiment of the present invention, the preset control method is to reduce the supply air flow, and the preset time period is A. The control module 101 controls the medical ventilator to reduce the time of the supply air flow A during the ventilation process. In order to inhibit the gas delivery of medical ventilation equipment.

Specifically, in the embodiment of the present invention, the step of the control module 101 inhibiting the medical ventilator from performing gas delivery within a preset time period according to a preset control method includes: obtaining a preset inhibition period; and periodically according to the preset inhibition period. The medical ventilation device is prevented from delivering gas within a preset time period according to a preset control method.

It should be noted that, in the embodiment of the present invention, a preset suppression period is preset in the gas concentration measurement device, which is used to limit the repetitive execution of the suppression of the medical ventilation device for gas delivery. The control module 101 can directly obtain the preset suppression Period, the specific preset suppression period is not limited in the embodiment of the present invention.

Exemplarily, in the embodiment of the present invention, the preset control method is to stop the air supply, the preset time period is A, and the preset suppression period is T. After obtaining the preset suppression period T, the control module 101 controls the medical ventilation device to stop air delivery for a time A every time T during the invasive or non-invasive ventilation of the medical ventilation device to inhibit the medical ventilation device from delivering gas.

Specifically, in the embodiment of the present invention, the step of the control module 101 inhibiting the medical ventilator from performing gas delivery within a preset time period according to a preset control method may further include: receiving a trigger instruction, and controlling according to the preset according to the trigger instruction The method inhibits the medical ventilation equipment from delivering gas within a preset time period.

It is understandable that, in the embodiment of the present invention, a display interface and buttons may be provided on the medical ventilation equipment or gas concentration monitoring device, and the medical staff can perform touch operations on the display interface, or press a specific button , That is, send the start and end trigger instructions to the control module 101 of the gas concentration measurement device, and the control module 101 can receive the trigger instruction in accordance with the preset control mode within the preset time period between the start and end trigger commands. Suppress medical ventilation equipment from delivering gas.

In the embodiment of the present invention, the control module 101 may also obtain the patient's physiological parameters before performing the step of inhibiting the medical ventilation device from performing gas delivery within a preset period of time according to the preset control mode; if the patient's physiological parameters represent the patient In a stable state, the step of inhibiting the medical ventilation device from delivering gas within a preset time period according to the preset control method is executed.

It is understandable that, in the embodiment of the present invention, the control module 101 inhibits the medical ventilation equipment from performing gas delivery, which will have a certain impact on patients who use the medical ventilation equipment for ventilation. Therefore, the control module 101 can first obtain Physiological parameters of the patient to determine whether it is currently suitable to inhibit the gas delivery of the medical ventilation device, and to avoid inhibiting the gas delivery of the medical ventilation device when the patient is in a bad state, aggravating the patient's condition, or causing the patient to present a dangerous situation.

It should be noted that in the embodiment of the present invention, the patient's physiological signs parameters include at least one of the following: heart rate, blood oxygen, pulse, respiration rate, peak pressure, average pressure, blood pressure, tidal volume, and body temperature. Of course, also Other parameters that can reflect the patient's status can be included. The specific physiological parameters of the patient are not limited in the embodiment of the present invention.

It should be noted that in the embodiment of the present invention, the control module 101 can directly obtain the patient's physiological sign data collected by related devices or equipment, for example, it can be attached to the patient's body through electrodes to extract the patient's ECG signal , And provided to the control module 101, the specific method for obtaining the patient's physiological parameters is not limited in the embodiment of the present invention.

In the embodiment of the present invention, when the control module 101 executes the step of inhibiting the medical ventilation device from performing gas delivery within a preset time period according to the preset control mode, it can also obtain the patient's physiological parameters. If the patient's physiological parameters represent the patient In an abnormal state, stop performing the step of inhibiting the medical ventilation device from delivering gas within a preset time period according to the preset control mode, and control the medical ventilation device to perform ventilation according to the preset ventilation mode and/or output patient abnormality prompts.

It is understandable that, in the embodiment of the present invention, the control module 101 obtains the patient's physiological parameters when inhibiting the medical ventilation device from performing gas delivery to determine whether the patient has discomfort or abnormality. If discomfort or abnormality occurs, it can be timely Stop the current suppression control and/or prompting of the medical ventilation equipment to avoid aggravating the patient's condition or causing the patient to present a dangerous situation.

It should be noted that, in the embodiment of the present invention, the control module 101 can determine the physiological parameters of the patient in a preset manner to indicate whether the patient is in a stable state or an abnormal state.

Specifically, in the embodiment of the present invention, the control module 101 may pre-store the relevant thresholds of the patient's physiological sign parameters, for example, the maximum threshold and the minimum threshold. If the patient's physiological sign parameters are less than or equal to the maximum threshold and greater than or equal to the minimum threshold, The control module 101 determines that the patient is in a stable state. If the patient's physiological parameters are greater than the maximum threshold or less than the minimum threshold, the control module 101 determines that the patient is in an abnormal state. The specific maximum and minimum thresholds can be set or set by the user according to actual needs. Determined by the internal calculation of the control module 101.

Specifically, in the embodiment of the present invention, the control module 101 can also calculate the rate of change of the patient's physiological sign parameters and compare the pre-stored rate of change threshold. If the rate of change of the patient's physiological sign parameter is less than or equal to the preset rate of change threshold, Then it is judged that the patient is in a stable state. If the change rate of the patient's physiological signs parameters is greater than the change rate threshold, it is judged that the patient is in an abnormal state. The specific change rate threshold can be set by the user according to actual needs or determined by the internal calculation of the control module 101 .

Specifically, in the embodiment of the present invention, the control module 101 can also simultaneously determine whether the patient is in a stable state or an abnormal state based on the patient's physiological parameters and the rate of change of the patient's physiological parameters, that is, if the patient's physiological parameters are greater than the maximum threshold or If it is less than the minimum threshold, and the change rate of the patient's physiological signs parameter is greater than the change rate threshold, it is determined that the patient is in an abnormal state, and in other situations, it is determined that the patient is in a stable state. The specific maximum threshold, minimum threshold, and change rate threshold can be independently set by the user according to actual needs or determined by internal calculation of the control module 101.

It should be noted that, in the embodiment of the present invention, the control module 101 controls the medical ventilation device to ventilate according to a preset ventilation mode, where the preset ventilation mode may be the ventilation mode before the medical ventilation device inhibits gas delivery, or It is another ventilation mode different from the ventilation mode before the medical ventilation device inhibits gas delivery, and the specific preset ventilation mode is not limited in the embodiment of the present invention.

It should be noted that, in the embodiment of the present invention, the control module 101 can output the patient abnormality prompt to the display configured by the medical ventilation equipment. Of course, the gas concentration measurement device itself can also be equipped with an independent display module, and the control module 101 outputs The patient’s abnormality prompt is given to the display module. After seeing the medical staff, the medical staff can make corresponding treatment in time to avoid the patient’s unexpected situation. Of course, the gas concentration measuring device or medical ventilation equipment can also include an alarm module, and the control module 101 outputs the patient abnormality prompt to Alarm module, the alarm module immediately emits an alarm tone.

In the embodiment of the present invention, when the control module 101 executes the step of inhibiting gas delivery within a preset time period in accordance with a preset control method, if a stop instruction is received, it stops executing in the preset time period in accordance with the preset control method. The step of internally restraining the medical ventilation device from performing gas delivery, and controlling the medical ventilation device to ventilate according to the preset ventilation mode. Of course, performing ventilation according to the preset ventilation mode can also restore the ventilation mode before the gas concentration measurement.

It is understandable that in the embodiment of the present invention, the medical operator can also send a stop instruction to the control module 101 through the display interface and the corresponding specific key set on the medical ventilation device or gas concentration measurement device to preset Stop inhibiting the medical ventilator from performing gas delivery at any time within the time period, and control the medical ventilator to ventilate according to a preset ventilation mode.

In the embodiment of the present invention, the control module 101 controls the medical ventilation device to perform ventilation according to the preset ventilation mode after performing the step of inhibiting the medical ventilation device from performing gas delivery within a preset time period according to the preset control mode.

It is understandable that, in the embodiment of the present invention, if the control module 101 does not receive a stop instruction within the preset time period, or the acquired patient's physiological signs and parameters indicate that the patient is in a normal state, then in the preset time period The internal control module 101 will always inhibit the medical ventilation device from performing gas delivery according to the preset control mode until the end of the preset time period, and then control the medical ventilation device to ventilate according to the preset ventilation mode.

In the embodiment of the present invention, the control module 101 may also perform non-invasive or invasive ventilation according to the preset oxygen concentration before performing the step of inhibiting the medical ventilation device from performing gas delivery within a preset time period according to a preset control method. Perform oxygenation ventilation during the process. Of course, the preset oxygen concentration for performing oxygen-enhancing ventilation can be input by the doctor or stored in advance, or it can be calculated based on the patient's physiological parameters, patient status, patient age, ventilation parameters, and the preset period of time for ventilation inhibition.

It is understandable that, in the embodiment of the present invention, the control module 101 inhibits the medical ventilation device from performing gas delivery, and the patient who uses the medical ventilation device for ventilation will lack oxygen within a preset time. Therefore, before the suppression, the control module 101 According to the preset oxygen concentration, oxygen-enhancing ventilation is performed to reduce the patient's hypoxia when the gas delivery is inhibited.

It should be noted that, in the embodiment of the present invention, when the control module 101 executes the step of inhibiting the medical ventilator from performing gas delivery within a preset time period in accordance with the preset control method, it may also output the relevant information corresponding to the preset control method. At least one of the parameters, the preset time period, the patient's physiological signs parameters and/or waveforms acquired during the preset time period, and the preset threshold corresponding to the patient's physiological signs parameters, etc. The medical operator can view these data in real time , In order to perform corresponding operations according to actual needs.

S202. Measure the target gas concentration within a preset time period; where the target gas concentration is the concentration of any gas component in the patient's exhaled air.

In the embodiment of the present invention, the control module 101 of the gas concentration measurement device inhibits the medical ventilation device from performing gas delivery in a preset time period according to a preset control method, and the measurement module 102 measures the target gas concentration in the preset time period.

It should be noted that, in the embodiment of the present invention, the target gas concentration is the concentration of any gas component in the patient's exhaled gas, for example, carbon dioxide, oxygen, etc.

It is understandable that, in the embodiment of the present invention, the measurement module 102 measures the target gas concentration when the medical ventilation device is inhibited from gas delivery within a preset time period, which can reduce the exposure of the patient’s exhaled gas to the fresh gas delivered by the patient segment. Dilution degree, so as to accurately measure the concentration of the target gas in the living gas of the patient.

FIG. 3 is a schematic diagram 1 of a change in airway pressure when a medical ventilation device for suppressing ventilation is provided by an embodiment of the present invention. As shown in Figure 3, when the control module 101 reduces the air flow or stops the air delivery to inhibit the medical ventilation equipment from delivering gas, the airway pressure will drop rapidly from time t1 to time t2, which is the preset time period At the end of the day, when ventilation is performed according to the preset ventilation mode, the airway pressure will rise rapidly. FIG. 4 is a schematic diagram of the change of the air delivery flow rate when the medical ventilation device is inhibited from performing ventilation according to an embodiment of the present invention. As shown in FIG. 4, when the control module 101 suppresses the medical ventilator from performing gas delivery by reducing the gas flow or stopping the gas flow, the gas flow rate will drop rapidly. Fig. 5 is a schematic diagram of a change in the concentration of carbon dioxide during ventilation of a medical ventilation device provided by an embodiment of the present invention. As shown in Fig. 4, the measurement module 102 measures the carbon dioxide measured during the preset time period during which the control module 101 reduces the air flow or stops the air supply from the medical ventilator from delivering gas, that is, from time t1 to time t2 The concentration value of is significantly higher than the measured value at other moments. It is precisely because the medical ventilation device is inhibited from gas delivery in step S201, so that the accurate carbon dioxide concentration value is measured.

In the embodiment of the present invention, the step of measuring the target gas concentration by the measurement module 102 within the preset time period includes: starting to measure the target gas concentration at a time interval from the start time of the preset time period to the preset time interval.

In order to measure a more accurate target gas concentration, it is also possible to start measuring the target gas concentration after the gas delivery is inhibited for a period of time, that is, after a period of time interval from the beginning of the preset time period. Of course, the measurement module 102 may also start measuring the target gas concentration when the control module 102 initially inhibits the medical ventilator from performing gas delivery. The specific preset time interval is not limited in the embodiment of the present invention.

Exemplarily, in the embodiment of the present invention, the preset control mode is to reduce the air flow, the preset time period is A, and the preset time interval is B. The control module 101 controls the medical ventilation equipment during the ventilation process. The duration of the air supply flow A is reduced. Specifically, after the start of the reduction of the air supply flow, the measurement module 102 starts to measure the target gas concentration after the duration B passes.

In the embodiment of the present invention, the step of measuring the target gas concentration by the measuring module 102 within a preset time period includes: if the measured target gas concentration changes rule within the preset time period, stopping the execution in accordance with the preset control mode. The step of inhibiting the medical ventilation device from performing gas delivery within the preset time period, and controlling the medical ventilation device to perform ventilation according to the preset ventilation mode.

It can be understood that, in the embodiment of the present invention, the measurement module 102 can always measure the target gas concentration within a preset time period. Therefore, it can determine the change of the target gas concentration in real time. If the change is regular, the measurement is relatively stable. , The measured target gas concentration is more accurate. As shown in Figure 5, between t1 and t2, the concentration of carbon dioxide at the end of the expiration measured at the beginning changes irregularly, and the measured concentration of the next two periods begins to change regularly, that is, the measured value tends to stabilize. Therefore, even when the end of the preset time period is not reached, the measurement module 102 can end the measurement, and the control module 101 directly stops performing the steps of inhibiting gas delivery, and restores the original ventilation mode as soon as possible, or performs normal ventilation according to other ventilation modes .

It should be noted that, in the embodiment of the present invention, the measuring module 102 may also output the target gas concentration and/or waveform after performing the step of measuring the target gas concentration within a preset time period. The medical staff can make relevant medical diagnosis after viewing the target gas concentration and/or waveform. The specific output form is not limited in the embodiment of the present invention.

In the embodiment of the present invention, when the measurement module 102 executes the step of measuring the target gas concentration within a preset time period, it may also execute the following steps: obtain the current gas flow rate.

It should be noted that, in the embodiment of the present invention, the control module 101 inhibits the medical ventilator from performing gas delivery by reducing the air flow or stopping the air supply, that is, reducing the air delivery flow rate or directly controlling the air delivery flow rate to 0, the measurement module 102 It can directly measure the current air delivery flow rate when the medical ventilation device is performing gas delivery. In addition, the measurement module 102 can also measure the ventilation parameters of the medical ventilation device during gas delivery, such as patient pressure, machine pressure, and leakage, etc., and calculate the current delivery flow rate through the ventilation parameters, that is, indirectly obtain the current delivery flow rate. . The specific method for obtaining the current air supply flow rate is not limited in the embodiment of the present invention.

In the embodiment of the present invention, the measurement module 102 obtains the current gas flow rate. Therefore, after performing the step of measuring the target gas concentration within a preset time period, the following steps may be performed: The gas concentration is compensated.

It should be noted that, in the embodiment of the present invention, the concentration compensation formula can be determined in advance according to actual requirements, and the current gas flow rate and the measured target gas concentration can be substituted into the concentration compensation formula to perform the measured target gas concentration. Compensation, the target gas concentration after compensation is obtained, and the target gas concentration after compensation is the more realistic target gas concentration. The specific concentration compensation formula is not limited in the embodiment of the present invention.

Exemplarily, in the embodiment of the present invention, the measurement is the end-tidal carbon dioxide concentration, and the concentration compensation formula may be predetermined as:

EtCO ₂ (0)=f(EtCO ₂ (n), Flow(n)) (1)

Among them, EtCO ₂ (0) is the compensated end-tidal carbon dioxide concentration, EtCO ₂ (n) is the measured end-tidal carbon dioxide concentration, and Flow(n) is the current delivery flow rate.

It should be noted that, in the embodiment of the present invention, the specific formula (1) can be specifically determined according to actual requirements. The following examples illustrate the method of determining the concentration compensation formula.

Exemplarily, in the embodiment of the present invention, the air delivery flow rate and the measured end-tidal carbon dioxide concentration are negatively correlated. Assuming that the two are in a linear relationship, it can be assumed that the concentration compensation formula is specifically:

EtCO ₂ (n)=EtCO ₂ (0)-b×Flow(n) (2)

Among them, b is the compensation coefficient, which can measure the end-tidal carbon dioxide concentration at different air flow rates and substitute it into formula (2) to determine the value of b.

Exemplary, in the embodiment of the present invention, the air supply flow rate is measured end-tidal carbon dioxide concentration in 5LPM EtCO ₂ (5), and measuring the flow rate of the air supply to the end-tidal carbon dioxide concentration in EtCO 10LPM ₂ (10) , Substituting formula (2), the following formula is obtained:

EtCO ₂ (5)=EtCO ₂ (0)-b×5 (3)

EtCO ₂ (10)=EtCO ₂ (0)-b×10 (4)

Simultaneous formula (3) and formula (4) can determine b, as follows:

b=(EtCO ₂ (5)-EtCO ₂ (10))/5 (5)

Substituting the determined specific value of b into formula (2), the determined concentration compensation formula can be obtained.

Exemplarily, in one embodiment, the air delivery flow rate and the measured end-tidal carbon dioxide concentration are negatively correlated. Assuming that the two are in a reciprocal relationship, it can be assumed that the concentration compensation formula is specifically:

EtCO ₂ (n)=EtCO ₂ (0)/(1+b×Flow(n)) (6)

Among them, b is the compensation coefficient, which can measure the end-tidal carbon dioxide concentration at different air flow rates and substitute it into formula (6) to determine the value of b.

Exemplarily, in another embodiment, the end-tidal carbon dioxide concentration EtCO ₂ (5) at a delivery air flow rate of 5 LPM is measured, and the end-tidal carbon dioxide concentration EtCO ₂ (10) at a delivery air flow rate of 10 LPM is measured, Substituting formula (6), the following formula is obtained:

EtCO ₂ (5)=EtCO ₂ (0)/(1+b×5) (7)

EtCO ₂ (10)=EtCO ₂ (0)/(1+b×10) (8)

Simultaneous formula (7) and formula (8) can determine b, as follows:

b=(EtCO ₂ (5)-EtCO ₂ (10))/(10×EtCO ₂ (10)-5×EtCO ₂ (5)) (9)

Substituting the determined specific value of b into formula (6), the determined concentration compensation formula can be obtained.

It is understandable that, in the embodiment of the present invention, after the two concentration compensation formulas mentioned above have determined the compensation parameter b, in the actual measurement process, the actually measured end-tidal carbon dioxide concentration can be obtained and obtained The current aspiration flow rate when the end-tidal carbon dioxide concentration is measured is substituted into it to calculate the compensated end-tidal carbon dioxide concentration.

It should be noted that, in the embodiment of the present invention, when the measurement module 102 executes the step of measuring the target gas concentration within a preset time period, it may also perform the following steps: obtain the patient's physiological sign parameters; according to the patient's physiological sign data, Determine whether the measured target gas concentration is abnormal.

It is understandable that in the embodiment of the present invention, when the measurement module 102 executes the step of measuring the target gas concentration within a preset time period, the nasal mask used by the patient may become loose, the patient may cry, or cough, etc. It will have an impact on the measurement, which is manifested in the fluctuation of the patient's physiological parameters, for example, when the patient is crying, the heartbeat speeds up, and the measured target gas concentration is abnormal, that is, inaccurate. The specific method for determining whether the target gas concentration is abnormal is not limited in the embodiment of the present invention.

The embodiment of the present invention provides a gas concentration measurement method, which is applied to medical ventilation equipment. During ventilation, the medical ventilation equipment is inhibited from performing gas delivery within a preset time period according to a preset control mode; within the preset time period The target gas concentration is measured; the target gas concentration is the concentration of any gas component in the patient's exhaled breath. In other words, the technical solution of the embodiment of the present invention can accurately measure the target gas concentration in the patient's exhaled breath when the patient is ventilated.

Another embodiment of the present invention provides a gas concentration measurement device. As shown in Figure 1, the device includes:

The control module 101, during the ventilation process, inhibits the medical ventilation device from performing gas delivery within a preset time period according to a preset control mode;

The measurement module 102 measures the target gas concentration within a preset time period; where the target gas concentration is the concentration of any gas component in the patient's breath.

Optionally, the preset control mode is to reduce the air flow or stop the air flow.

Optionally, the step of the control module 101 inhibiting the medical ventilator from performing gas delivery within a preset time period according to a preset control mode includes:

Obtain a preset suppression period; according to the preset suppression period, periodically and according to a preset control mode, the medical ventilation device is inhibited from gas delivery within a preset time period.

Optionally, the step of the control module 102 inhibiting the medical ventilation device from performing gas delivery within a preset time period according to a preset control mode includes:

The trigger instruction is received, and the medical ventilation device is inhibited from performing gas delivery in a preset time period according to the preset control mode according to the trigger instruction.

Optionally, the control module 101 obtains the patient's physiological parameters before performing the step of inhibiting the medical ventilation device from performing gas delivery within a preset time period according to a preset control mode; if the patient's physiological parameters indicate that the patient is in a stable state, Perform the step of inhibiting the medical ventilation device from performing gas delivery within a preset time period according to a preset control method.

Optionally, when the control module 101 executes the step of inhibiting the medical ventilation device from performing gas delivery within a preset time period in accordance with a preset control method, obtain the patient's physiological parameters; if the patient's physiological parameters indicate that the patient is in an abnormal state, stop The step of inhibiting the medical ventilation device from performing gas delivery within a preset time period according to a preset control mode, and controlling the medical ventilation device to perform ventilation according to a preset ventilation mode and/or output a patient abnormality prompt.

Optionally, the measurement module 102 starts to measure the target gas concentration at a time that is a preset time interval from the start time of the preset time period.

Optionally, if the target gas concentration measured by the measurement module 102 changes regularly within a preset time period, the control module stops inhibiting the medical ventilation device from performing gas delivery, and controls the medical ventilation device to ventilate according to the preset ventilation mode.

Optionally, when the control module 101 executes the step of inhibiting gas delivery within a preset time period according to a preset control method, if a stop instruction is received, it stops executing the step of inhibiting medical ventilation within a preset time period according to the preset control method. The device performs the gas delivery step, and controls the medical ventilation device to ventilate according to the preset ventilation mode.

Optionally, the control module 101 controls the medical ventilation device to perform ventilation according to a preset ventilation mode after performing the step of inhibiting the medical ventilation device from performing gas delivery within a preset time period according to a preset control manner.

Optionally, the measurement module 102 outputs the measured target gas concentration and/or waveform after performing the step of measuring the target gas concentration within a preset time period.

Optionally, the control module 101 performs oxygen-enhancing ventilation on the patient before performing the step of inhibiting the medical ventilation device from performing gas delivery within a preset time period according to a preset control mode.

Optionally, the measurement module 102 obtains the current gas flow rate when performing the step of measuring the target gas concentration within a preset time period.

Optionally, after the measurement module 102 executes the step of measuring the target gas concentration within a preset time period, it compensates the measured target gas concentration according to the current gas flow rate.

Optionally, when the measurement module 102 executes the step of measuring the target gas concentration within a preset time period, it also obtains the patient's physiological sign parameters; according to the patient's physiological sign parameters, judge whether the measured target gas concentration is abnormal.

The embodiment of the present invention provides a gas concentration measuring device, which inhibits medical ventilation equipment from performing gas delivery within a preset time period according to a preset control mode during ventilation; measures the target gas concentration within the preset time period; wherein , The target gas concentration is the concentration of any gas component in the patient's exhaled breath. In other words, the gas concentration measuring device provided by the embodiment of the present invention can accurately measure the target gas concentration in the patient's exhaled air when the patient is ventilated.

The embodiment of the present invention also provides a medical ventilation device. Fig. 6 is a schematic structural diagram of a medical ventilation device provided by an embodiment of the present invention. As shown in FIG. 6, the medical ventilation equipment includes the above-mentioned gas concentration measuring device 601, and also includes: a gas source 602, a breathing tube 603, and a display 604;

Gas source 602, which provides gas during ventilation;

The breathing tube 603 is connected to the air source 602 to provide a breathing path during ventilation;

The gas concentration measuring device 601 is connected with the breathing tube 603, the gas source 602 and the display 604;

The gas concentration measuring device 601 measures the target gas concentration during ventilation.

For ventilators, especially neonatal ventilators, the gas concentration measurement method or gas concentration measurement device provided in this embodiment is used to suppress gas delivery within a preset time period, which can improve the accuracy of gas concentration measurement.

The embodiment of the present invention provides a computer-readable storage medium that stores a gas concentration measurement program, and the gas concentration measurement program can be executed by a processor to implement the above-mentioned gas concentration measurement method. The computer-readable storage medium may be a volatile memory (volatile memory), such as random-access memory (Random-Access Memory, RAM); or a non-volatile memory (non-volatile memory), such as read-only memory (Read Only Memory). -Only Memory, ROM, flash memory, Hard Disk Drive (HDD) or Solid-State Drive (SSD); it can also be a respective device including one or any combination of the above-mentioned memories, Such as mobile phones, computers, tablet devices, personal digital assistants, etc.

Those skilled in the art should understand that the embodiments of the present invention may be provided as methods, systems, or computer program products. Therefore, the present invention may adopt the form of a hardware embodiment, a software embodiment, or an embodiment combining software and hardware. Moreover, the present invention may adopt the form of a computer program product implemented on one or more computer-usable storage media (including but not limited to disk storage, optical storage, etc.) containing computer-usable program codes.

The present invention is described with reference to flowcharts and/or block diagrams of methods, devices (systems), and computer program products according to embodiments of the present invention. It should be understood that each process and/or block in the flowchart and/or block diagram, and the combination of processes and/or blocks in the flowchart and/or block diagram can be implemented by computer program instructions. These computer program instructions can be provided to the processor of a general-purpose computer, a special-purpose computer, an embedded processor, or other programmable signal processing equipment to generate a machine, so that the instructions executed by the processor of the computer or other programmable signal processing equipment are generated It is a device that realizes the functions specified in one process or multiple processes in the flowchart and/or one block or multiple blocks in the block diagram.

These computer program instructions can also be stored in a computer-readable memory that can guide a computer or other programmable signal processing equipment to work in a specific manner, so that the instructions stored in the computer-readable memory produce an article of manufacture including the instruction device. The device implements the functions specified in one process or multiple processes in the flowchart and/or one block or multiple blocks in the block diagram.

These computer program instructions can also be loaded on a computer or other programmable signal processing equipment, so that a series of operation steps are executed on the computer or other programmable equipment to produce computer-implemented processing, so as to execute on the computer or other programmable equipment. The instructions provide steps for implementing functions specified in a flow or multiple flows in the flowchart and/or a block or multiple blocks in the block diagram.

The above are only the preferred embodiments of the present invention, and are not used to limit the protection scope of the present invention.

Industrial applicability

In the technical solution of the embodiment of the present invention, during the ventilation process, the medical ventilation device is inhibited from performing gas delivery within a preset time period according to a preset control mode; the target gas concentration is measured within the preset time period; wherein the target gas The concentration is the concentration of any gas component in the patient's breath. In other words, the gas concentration measuring device provided by the embodiment of the present invention can accurately measure the target gas concentration in the patient's exhaled air when the patient is ventilated.

Claims (34)

1. A gas concentration measurement method applied to medical ventilation equipment, characterized in that the method includes:

   During the ventilation process, inhibit the medical ventilation device from performing gas delivery within a preset time period according to a preset control method;

   The target gas concentration is measured within the preset time period; wherein the target gas concentration is the concentration of any gas component in the patient's exhaled air.
2. The method according to claim 1, wherein the preset control method is to reduce the air flow or stop the air flow.
3. The method according to claim 1, wherein the step of inhibiting the medical ventilation device from performing gas delivery within a preset time period according to a preset control method comprises:

   Obtain the preset suppression period;

   According to the preset suppression period, periodically and according to the preset control mode, the medical ventilation device is inhibited from performing gas delivery within the preset time period.
4. The method according to claim 1, wherein the step of inhibiting the medical ventilation device from performing gas delivery within a preset time period according to a preset control method comprises:

   Receiving a trigger instruction, and inhibiting the medical ventilator from performing gas delivery within the preset time period according to the preset control mode according to the trigger instruction.
5. The method according to claim 1, characterized in that, before performing the step of inhibiting the medical ventilator from performing gas delivery within a preset time period according to a preset control mode, the method further comprises:

   Obtain the physiological parameters of the patient;

   If the physiological parameters of the patient indicate that the patient is in a stable state, the step of inhibiting the medical ventilation device from performing gas delivery within a preset time period according to a preset control mode is executed.
6. The method according to claim 1, wherein when performing the step of inhibiting gas delivery by the medical ventilation device within a preset time period according to a preset control mode, the method further comprises:

   Obtain the physiological parameters of the patient;

   If the physiological parameters of the patient indicate that the patient is in an abnormal state, stop performing the step of inhibiting the medical ventilation device from performing gas delivery within a preset time period according to the preset control mode, and control the medical ventilation device to follow the preset Ventilation mode performs ventilation and/or outputs patient abnormal prompts.
7. The method according to claim 1, wherein the step of measuring the target gas concentration within the preset time period comprises:

   Start measuring the target gas concentration at a time that is a preset time interval from the start time of the preset time period.
8. The method according to claim 1, wherein the step of measuring the target gas concentration within the preset time period comprises:

   If the measured target gas concentration changes during the preset time period, stop performing the step of inhibiting the medical ventilation device from performing gas delivery within the preset time period according to the preset control mode, and control the medical The ventilation device performs ventilation according to a preset ventilation mode.
9. The method according to claim 1, wherein when performing the step of inhibiting gas delivery within a preset time period according to a preset control mode, the method further comprises:

   If a stop instruction is received, stop performing the step of inhibiting the medical ventilator from performing gas delivery within a preset time period according to the preset control mode, and control the medical ventilator to perform ventilation according to the preset ventilation mode.
10. The method according to claim 1, wherein after performing the step of inhibiting the medical ventilation device from performing gas delivery within a preset time period according to a preset control mode, the method further comprises:

    The medical ventilation device is controlled to ventilate according to a preset ventilation mode.
11. The method according to claim 1, characterized in that, after performing the step of measuring the target gas concentration within the preset time period, the method further comprises:

    Output the measured target gas concentration and/or waveform.
12. The method according to claim 1, characterized in that, before performing the step of inhibiting the medical ventilator from performing gas delivery within a preset time period according to a preset control mode, the method further comprises:

    The patient is ventilated with oxygen.
13. The method according to claim 1, wherein when performing the step of measuring the target gas concentration within the preset time period, the method further comprises:

    Get the current air flow rate.
14. The method according to claim 13, characterized in that, after performing the step of measuring the target gas concentration within the preset time period, the method further comprises:

    The measured target gas concentration is compensated according to the current gas flow rate.
15. The method according to claim 1, wherein when performing the step of measuring the target gas concentration within the preset time period, the method further comprises:

    Obtain the physiological parameters of the patient;

    According to the physiological sign data of the patient, it is judged whether the measured target gas concentration is abnormal.
16. The method according to claim 1, wherein when performing the step of inhibiting gas delivery by the medical ventilation device within a preset time period according to a preset control mode, the method further comprises:

    Output the relevant parameters corresponding to the preset control mode, the preset time period, the patient's physiological sign parameters and/or waveforms acquired during the preset time period, and the preset threshold corresponding to the patient's physiological sign parameters At least one of them.
17. A gas concentration measuring device applied to medical ventilation equipment, characterized in that the device comprises:

    The control module, during the ventilation process, inhibits the medical ventilation device from delivering gas within a preset time period according to a preset control mode;

    The measurement module measures the target gas concentration within the preset time period; wherein the target gas concentration is the concentration of any gas component in the patient's exhaled air.
18. The device according to claim 17, wherein the preset control method is to reduce the air flow or stop the air flow.
19. The device according to claim 17, wherein the step of the control module inhibiting the medical ventilation device from performing gas delivery within a preset time period according to a preset control mode comprises:

    Obtain a preset suppression period; according to the preset suppression period, periodically and according to the preset control mode, suppress the medical ventilation device from performing gas delivery within the preset time period.
20. The device according to claim 17, wherein the step of the control module inhibiting the medical ventilation device from performing gas delivery within a preset time period according to a preset control mode comprises:

    Receiving a trigger instruction, and inhibiting the medical ventilator from performing gas delivery within the preset time period according to the preset control mode according to the trigger instruction.
21. The device according to claim 17, wherein:

    The control module obtains the patient's physiological parameters before performing the step of inhibiting the medical ventilation device from performing gas delivery within a preset period of time according to the preset control mode; if the patient's physiological parameters indicate that the patient is in a stable state Then, the step of inhibiting the medical ventilation device from performing gas delivery within a preset time period according to a preset control mode is executed.
22. The device according to claim 17, wherein:

    When the control module executes the step of inhibiting the medical ventilation device from performing gas delivery within a preset time period according to a preset control mode, obtain the patient's physiological parameter; if the patient's physiological parameter indicates that the patient is in an abnormal state , Stop the step of inhibiting the medical ventilation device from performing gas delivery within a preset time period according to the preset control mode, and control the medical ventilation device to perform ventilation according to the preset ventilation mode and/or output a patient abnormality prompt.
23. The device according to claim 17, wherein:

    The measurement module starts to measure the target gas concentration at a time that is a preset time interval from the start time of the preset time period.
24. The device according to claim 17, wherein:

    If the target gas concentration measured by the measurement module within the preset period of time changes regularly, the control module stops inhibiting the medical ventilation device from performing gas delivery, and controls the medical ventilation device to follow the preset ventilation mode Perform ventilation.
25. The device according to claim 17, wherein when the control module is executing the step of suppressing gas delivery within a preset time period according to a preset control method, if a stop instruction is received, it stops executing the The step of inhibiting the medical ventilation device from performing gas delivery within a preset time period according to a preset control manner, and controlling the medical ventilation device to perform ventilation according to a preset ventilation mode.
26. The device according to claim 17, wherein:

    The control module controls the medical ventilation device to perform ventilation according to a preset ventilation mode after performing the step of inhibiting the medical ventilation device from performing gas delivery within a preset time period according to a preset control manner.
27. The device according to claim 17, wherein:

    The measurement module outputs the measured target gas concentration and/or waveform after performing the step of measuring the target gas concentration within the preset time period.
28. The device according to claim 17, wherein:

    The control module performs oxygen-enhancing ventilation on the patient before performing the step of inhibiting the medical ventilation device from performing gas delivery within a preset time period according to the preset control mode.
29. The device according to claim 17, wherein:

    The measurement module acquires the current air supply flow rate when executing the step of measuring the target gas concentration within the preset time period.
30. The device of claim 29, wherein:

    After the measurement module executes the step of measuring the target gas concentration within the preset time period, it compensates for the measured target gas concentration according to the current air supply flow rate.
31. The device according to claim 17, wherein:

    When the measurement module executes the step of measuring the target gas concentration within the preset time period, it also obtains the patient's physiological sign parameters; according to the patient's physiological sign parameters, it is determined whether the measured target gas concentration is abnormal.
32. A medical ventilation device comprising the gas concentration measuring device according to any one of claims 17-31, characterized in that it comprises a gas source, a breathing tube and a display;

    The gas source provides gas during ventilation;

    The breathing circuit is connected with the air source to provide a breathing path during the invasive or non-invasive ventilation;

    The gas concentration measuring device is connected with the breathing pipeline, the gas source and the display;

    The gas concentration measuring device measures the target gas concentration during the invasive or non-invasive ventilation.
33. The medical ventilation device according to claim 32, wherein the medical ventilation device is a neonatal ventilator.
34. A computer-readable storage medium, characterized in that the computer-readable storage medium stores a gas concentration measurement program, and the gas concentration measurement program can be executed by a processor to implement any one of claims 1-16 Method of measuring gas concentration.

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