WO2020121931A1 - Pest/mite control method and pest/mite control aerosol - Google Patents

Pest/mite control method and pest/mite control aerosol Download PDF

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Publication number
WO2020121931A1
WO2020121931A1 PCT/JP2019/047561 JP2019047561W WO2020121931A1 WO 2020121931 A1 WO2020121931 A1 WO 2020121931A1 JP 2019047561 W JP2019047561 W JP 2019047561W WO 2020121931 A1 WO2020121931 A1 WO 2020121931A1
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WO
WIPO (PCT)
Prior art keywords
aerosol
pest
control
mites
control component
Prior art date
Application number
PCT/JP2019/047561
Other languages
French (fr)
Japanese (ja)
Inventor
悠耶 原田
洋子 小林
由美 川尻
中山　幸治
Original Assignee
大日本除蟲菊株式会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=71076853&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2020121931(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 大日本除蟲菊株式会社 filed Critical 大日本除蟲菊株式会社
Priority to KR1020237024893A priority Critical patent/KR102655095B1/en
Priority to KR1020217017622A priority patent/KR102619497B1/en
Priority to AU2019399077A priority patent/AU2019399077B2/en
Priority to CN202211089914.0A priority patent/CN115568465A/en
Priority to CN201980082071.1A priority patent/CN113194719B/en
Priority to SG11202106323YA priority patent/SG11202106323YA/en
Priority to JP2020513945A priority patent/JP6718568B1/en
Publication of WO2020121931A1 publication Critical patent/WO2020121931A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01M—CATCHING, TRAPPING OR SCARING OF ANIMALS; APPARATUS FOR THE DESTRUCTION OF NOXIOUS ANIMALS OR NOXIOUS PLANTS
    • A01M7/00—Special adaptations or arrangements of liquid-spraying apparatus for purposes covered by this subclass
    • A01M7/0025—Mechanical sprayers
    • A01M7/0032—Pressure sprayers
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01M—CATCHING, TRAPPING OR SCARING OF ANIMALS; APPARATUS FOR THE DESTRUCTION OF NOXIOUS ANIMALS OR NOXIOUS PLANTS
    • A01M1/00—Stationary means for catching or killing insects
    • A01M1/20—Poisoning, narcotising, or burning insects
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01M—CATCHING, TRAPPING OR SCARING OF ANIMALS; APPARATUS FOR THE DESTRUCTION OF NOXIOUS ANIMALS OR NOXIOUS PLANTS
    • A01M7/00—Special adaptations or arrangements of liquid-spraying apparatus for purposes covered by this subclass
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01M—CATCHING, TRAPPING OR SCARING OF ANIMALS; APPARATUS FOR THE DESTRUCTION OF NOXIOUS ANIMALS OR NOXIOUS PLANTS
    • A01M7/00—Special adaptations or arrangements of liquid-spraying apparatus for purposes covered by this subclass
    • A01M7/005—Special arrangements or adaptations of the spraying or distributing parts, e.g. adaptations or mounting of the spray booms, mounting of the nozzles, protection shields
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01M—CATCHING, TRAPPING OR SCARING OF ANIMALS; APPARATUS FOR THE DESTRUCTION OF NOXIOUS ANIMALS OR NOXIOUS PLANTS
    • A01M7/00—Special adaptations or arrangements of liquid-spraying apparatus for purposes covered by this subclass
    • A01M7/0082—Undercarriages, frames, mountings, couplings, tanks
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
    • A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
    • A01N25/06—Aerosols
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/02—Saturated carboxylic acids or thio analogues thereof; Derivatives thereof
    • A01N37/04—Saturated carboxylic acids or thio analogues thereof; Derivatives thereof polybasic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/10—Aromatic or araliphatic carboxylic acids, or thio analogues thereof; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N53/00—Biocides, pest repellants or attractants, or plant growth regulators containing cyclopropane carboxylic acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
    • A01P7/00—Arthropodicides
    • A01P7/02—Acaricides
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
    • A01P7/00—Arthropodicides
    • A01P7/04—Insecticides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B9/00—Spraying apparatus for discharge of liquids or other fluent material, without essentially mixing with gas or vapour
    • B05B9/03—Spraying apparatus for discharge of liquids or other fluent material, without essentially mixing with gas or vapour characterised by means for supplying liquid or other fluent material
    • B05B9/04—Spraying apparatus for discharge of liquids or other fluent material, without essentially mixing with gas or vapour characterised by means for supplying liquid or other fluent material with pressurised or compressible container; with pump
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01M—CATCHING, TRAPPING OR SCARING OF ANIMALS; APPARATUS FOR THE DESTRUCTION OF NOXIOUS ANIMALS OR NOXIOUS PLANTS
    • A01M2200/00—Kind of animal
    • A01M2200/01—Insects
    • A01M2200/011—Crawling insects
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S43/00—Fishing, trapping, and vermin destroying
    • Y10S43/90—Liquid insecticide sprayer

Definitions

  • the present invention is a pest obtained by filling an aerosol stock solution containing a control component and an organic solvent, and a propellant into an aerosol container equipped with a metered injection valve having an injection volume of 1.0 to 5.0 mL per injection.
  • the present invention relates to a pest to be spray-treated with a tick control aerosol, a method for controlling ticks, and a pest and a tick control aerosol.
  • Targeting crawling pests such as cockroaches and indoor dust mites wandering around floors and walls, as a type of insecticide applied to places and passages where crawling pests and mites live, (1) smoking agents, Typical examples are (2) all-injection-type aerosol, (3) coating-type aerosol, and (4) bait agent, each of which has characteristics in terms of formulation.
  • Patent Document 1 is a method for exterminating crawling pests by evaporating an insecticidal liquid containing an insecticidal component and a solvent into a space such as an indoor space or a storage space, using a compound having a specific structure as a solvent, Disclosed is a method for exterminating crawling insect pests, which comprises evaporating the insecticidal liquid little by little with a piezo sprayer over a period of time so that the insecticidal liquid fine particles having a small particle diameter continue to float in the space.
  • Patent Document 1 proposes to continuously disperse a small amount of a drug into a space for a long time and exterminate cockroaches like liquid electric mosquito repellent, but it is several tens of times that of mosquitoes. Since it is targeted at the cockroaches that are strong against the drug, it is unavoidable to use a powerful insecticidal component, and thus there is an unavoidable safety concern for the human body.
  • the present inventors previously developed a space treatment agent, which is a quasi-drug-related non-pharmaceutical control agent for crawling pests and indoor dust mites, (1) smoking agent and (2) total amount Rather than a formulation that is used once every 2 to 4 weeks, such as a spray type aerosol, once a fixed amount spray treatment, the control effect lasts for several days under practical conditions, that is, basically 1 to 2 days.
  • a formulation to be used once a thorough study was conducted aiming at a highly safe formulation that can be used even in the presence of people.
  • the inventors have invented a very useful “pest and mite control method” (see Patent Document 2) that is effective not only for crawling pests and indoor dust mites but also for flying pests on the day of spraying.
  • the present invention has a spraying property of an aerosol, in which sprayed particles after spraying are buoyant particles, adhere to a wall surface and settle to a floor surface. It is designed so that 30 to 80% of all the spray particles adhere to the wall surface or the like or settle to the floor surface by 1 hour after the injection treatment, in addition to the formation of the adhesive particles involved. ..
  • the injection volume of the constant-quantity injection valve is generally 0.2 to 0.4 mL, and it is basically necessary to push the preparation several times (press the injection button) in one treatment. Was done.
  • Patent Document 3 discloses an aerosol product for exterminating crawling pests and a method for exterminating crawling pests using a constant-quantity injection valve.
  • This aerosol product increases the mixing ratio of the propellant contained in the aerosol container, lowers the vapor pressure of the solvent that dissolves the active ingredient, and increases the evaporation rate of the solvent that forms the particles injected from the aerosol container. It is characterized in that the particles are scattered to the depths of the indoor gap by slowing down. That is, the method of Patent Document 3 corresponds to (3) the local treatment by the coating type aerosol even if it is the quantitative injection treatment, and does not correspond to the spatial treatment. Therefore, even if a high extermination effect is locally obtained in a part of the gap, it is not possible to exterminate the crawling pest efficiently in the entire indoor area.
  • the present inventors have found that the spatial quantitative injection treatment based on Patent Document 2 is the most efficient pest and mite control method, and improve the convenience thereof, and in particular, the crawling pest.
  • the study was conducted with the aim of further improving the efficacy against indoor dust mites.
  • a recently developed quantitative injection valve with an injection capacity of 1.0 to 5.0 mL was used to enable injection of the required amount of active ingredient with one push.
  • the sprayed particles after injection are floating particles floating in the processing space and the adhesion that adheres to the exposed part in the processing space.
  • An object of the present invention is to control pests and mite pests and indoor dust mites with a single push of an aerosol for controlling pests and mites, which is equipped with a quantitative injection valve with a capacity of 1.0 to 5.0 mL. It is intended to provide a pest that can be maintained for a day, a method for controlling ticks, and an aerosol for controlling pests and ticks.
  • a pest obtained by filling an aerosol stock solution containing a control component and an organic solvent, and a propellant into an aerosol container equipped with a metered injection valve having an injection volume of 1.0 to 5.0 mL per time.
  • the control component is a hardly volatile compound having a vapor pressure at 30° C.
  • the specific gravity of the aerosol stock solution is 0.85 to 1.15
  • the spray force of the pest and mite control aerosol is 10 to 50 gf at a spray distance of 5 cm
  • the aerosol stock solution is injected into the air of the indoor space so that the release amount of the control component is 0.1 to 50 mg/m 3, and 60% of the control component is injected one hour after the injection.
  • the aerosol for controlling pests and mites has the following formula (3): 3.0 ⁇ ⁇ ⁇ 15 (3)
  • the sparingly volatile compound is at least one crawling insect pest control selected from the group consisting of phenothrin, cyphenothrin, permethrin, cypermethrin, cyfluthrin, bifenthrin, fenpropatrine, tralomethrin, etofenprox, and dinotefuran.
  • the method for controlling pests and mites according to any one of [1] to [4], which is a compound for use.
  • the sparingly volatile compound is amidoflumet, benzyl benzoate, phenyl salicylate, benzyl salicylate, dibutyl sebacate, dipropyl sebacate, dibutyl adipate, diethyl phthalate, dibutyl phthalate, and p-menthane-3,8.
  • a method for controlling ticks, and pests, and a mite control aerosol a specific pest containing a hardly volatile compound, an aerosol for controlling a ticks is just one push in an indoor space, and the treatment is carried out. Especially in the area, the control effect against the crawling pests and indoor dust mites can be maintained for several days. It is extremely practical because it provides a convenient and effective method for controlling pests and ticks, and an aerosol for controlling pests and ticks.
  • a fugitive compound having a vapor pressure at 30° C. of less than 1 ⁇ 10 ⁇ 4 mmHg is used as a control component.
  • a controlling component is the insect pest of the present invention, after the spray treatment of one-push aerosol for controlling ticks in the indoor space, mainly settles on the floor as adherent particles, especially in the indoor space crawling pests and indoor dust mites It shows an excellent control effect against.
  • the repelling effect is collectively referred to as a controlling effect. Even if the extermination effect is low, if there is a sufficient repellent effect, there are many cases where the control can be achieved in practice.
  • the present invention is based on the recognition that the spatial quantitative injection treatment based on Patent Document 2 is the most effective pest and mite control method, and improves the convenience thereof, and in particular, crawling pests and indoor dust mites. It is aimed at further improving the efficacy against various kinds.
  • a metered-quantity injection valve with a capacity of 1.0 to 5.0 mL which has been developed in recent years, was adopted to make it possible to inject the required amount of active ingredient with one push.
  • space treatment in order to improve the control effect especially against cockroaches among crawling pests, in order to increase the predominance of adherent particles among floating particles and adherent particles formed from sprayed particles after injection.
  • a crawling pest control compound for controlling crawling pests typified by cockroaches, and/or a tick control mainly for controlling indoor dust mites
  • compounds for use include phenothrin, cyphenothrin, permethrin, cypermethrin, cyfluthrin, bifenthrin, fenpropatrine, tralomethrin, etofenprox, and pyrethroid compounds such as imiprothrin, silafluofen and other silicon compounds, dichlorvos, and the like.
  • organophosphorus compounds such as fenitrothion, carbamate compounds such as propoxur, dinotefuran, imidacloprid, and neonicotinoid compounds such as clothianidin, and fipronil and indoxacarb.
  • organophosphorus compounds such as fenitrothion
  • carbamate compounds such as propoxur, dinotefuran, imidacloprid
  • neonicotinoid compounds such as clothianidin
  • fipronil and indoxacarb examples include organophosphorus compounds such as fenitrothion, carbamate compounds such as propoxur, dinotefuran, imidacloprid, and neonicotinoid compounds such as clothianidin, and fipronil and indoxacarb.
  • Examples of compounds for controlling ticks include amidoflumet, benzyl benzoate, phenyl salicylate, benzyl salicylate, dibutyl sebacate, dipropyl sebacate, dibutyl adipate, diethyl phthalate, dipropyl phthalate, dibutyl phthalate, p-menthane-3,8. Examples thereof include diol, 3-iodo-2-propynylbutyl carbamate, phenothrin, and diet.
  • Amidoflumet benzyl benzoate, phenyl salicylate, benzyl salicylate, dibutyl sebacate, dipropyl sebacate, dibutyl adipate, diethyl phthalate.
  • Preferred are dibutyl phthalate, p-menthane-3,8-diol, phenothrin, and diet.
  • a small amount of a fixed amount of an aerosol stock solution containing a control component and an organic solvent is sprayed in space.
  • the content of the controlling component in the undiluted aerosol solution is preferably about 1.0 to 70 w/v %. If the content of the control component in the aerosol stock solution is less than 1.0 w/v%, the desired control effect cannot be obtained, and if it exceeds 70 w/v%, there is difficulty in stabilizing the liquid properties of the aerosol stock solution.
  • a room temperature volatile control component having a pressure of 2 ⁇ 10 ⁇ 4 mmHg or more and less than 1 ⁇ 10 ⁇ 2 mmHg may be added.
  • Examples of such a room temperature volatile control component include metofluthrin, profluthrin, transfluthrin, empentrin, terrarethrin, and flamethrin.
  • the room-temperature volatile control component can synergistically enhance the control effect against crawling pests and/or indoor dust mites when partly attached to the floor surface or the wall surface together with the difficult-volatile control component.
  • the room temperature volatile control component considering the vapor pressure and stability, basic insecticidal efficacy, etc., metofluthrin, profluthrin, and transfluthrin are preferable, in the acid component and alcohol portion of these compounds, asymmetric carbon
  • the optical isomers and geometrical isomers based on them exist, each of them and any mixture thereof are of course included in the present invention.
  • an aerosol stock solution is formed by mixing an organic solvent in order to dissolve the above-mentioned volatile control components.
  • the organic solvent include lower alcohols having 2 to 3 carbon atoms, hydrocarbon solvents such as normal paraffin and isoparaffin, ester solvents such as isopropyl myristate (IPM) and hexyl laurate, and 3 to 10 carbon atoms.
  • the glycol ether-based solvent, the ketone-based solvent and the like are mentioned, but a lower alcohol having 2 to 3 carbon atoms represented by ethanol or isopropanol (IPA) is preferable.
  • the pest and mite control method of the present invention uses an aerosol for controlling pests and mites, which contains a volatile control component, and sprays the indoor space with a spray volume of 1.0 to 5.0 mL. Therefore, the control effect against the creeping insect pests and/or indoor dust mites in the treated area is maintained for several days.
  • the size of the indoor space should be a volume of 18.8-33.3m 3 (area 7.5-13.3m 2 , height 2.2-3.0m) that corresponds to a room of 4.5-8 tatami mats. Is preferred.
  • the sprayed particles after jetting are formed as floating particles floating in the processing space or adhesive particles adhering to an exposed portion in the processing space.
  • the present inventors have made the adhesive particles more dominant. None, and further, among the adhesive particles, a study was conducted to increase the ratio of the adhesive particles involved in sedimentation to the floor surface rather than to the wall surface. As a result, the present inventors have found that the specific gravity of the aerosol stock solution and the jetting force of the aerosol are important factors that determine the behavior of the adhesive particles involved in sedimentation, and to identify their optimum range. I arrived.
  • the specific gravity of the aerosol stock solution is 0.85 to 1.15, preferably 0.89 to 1.10, and the injection force of the injection treatment is 10 to 50 gf, preferably 15 to 35 gf at an injection distance of 5 cm, It was confirmed that 60% or more of the control components settled and adhered to the entire floor surface of the indoor space by 1 hour after the injection, and an excellent control effect against crawling pests and mites could be achieved. Regarding the "precipitation and adhesion of the control component over the entire floor surface", it is not necessary to check each time whether the control component actually deposits or adheres over the entire floor surface.
  • the control component will settle or adhere to the entire floor surface. It can be regarded as a living thing, and there is no practical problem even if it is regarded as such. If the specific gravity of the aerosol concentrate is less than 0.85, the amount of spray particles attached to the floor tends to be insufficient, and if the specific gravity of the aerosol concentrate exceeds 1.15, the settling of the spray particles will be too fast. As a result, the diffusion property over the entire floor surface becomes insufficient.
  • the injection force of the injection process is less than 10 gf, the injection force tends to be insufficient and the diffusivity over the entire floor surface tends to be insufficient. Even if the injection force exceeds 50 gf, good diffusivity can be obtained. I can't.
  • the spraying force of the aerosol can be appropriately adjusted by changing the formulation of the undiluted aerosol solution, the internal pressure of the aerosol, the shape of the injection port, and the like.
  • the pest and mite control aerosol has the following formula, where a is the amount of the undiluted solution of the aerosol, b is the amount of the propellant, S is the specific gravity of the undiluted aerosol solution, and F is the ejection force of the pest and mite controlling aerosol.
  • Formula (1): ⁇ [a/(a+b)] ⁇ S 2 ⁇ F (1) It is preferable that ⁇ defined in step 1 is in the range of 1.0 to 30, and more preferably in the range of 3.0 to 15.
  • ⁇ is in the range of 1.0 to 30, when the spray particles settle, a sufficient amount of the control component is uniformly diffused over the entire floor surface, so that a preferable control effect can be obtained.
  • the uniform distribution of the control component to the entire floor surface means that the initial velocity of the spray particles sprayed from the pest and mite control aerosol is appropriate, and the spray particles immediately spread to every corner of the indoor space after spraying. It is thought to be because.
  • ⁇ is less than 1.0, the amount of the control component attached to the floor surface may be insufficient.
  • ⁇ exceeds 30, the diffusivity over the entire floor surface may be insufficient. Therefore, if ⁇ is out of the range of 1.0 to 30, there is a possibility that a satisfactory control effect cannot be obtained.
  • the pest and mite control aerosol has a volume ratio [a/(a+b)] of the filling amount a of the undiluted aerosol solution to the total volume (a+b) of the pest and mite control aerosol, which is represented by the following formula (2): 0.1 ⁇ [a/(a+b)] ⁇ 0.5 (2) It is preferable to satisfy.
  • the volume ratio is within the above range, a sufficient amount of the controlling component is uniformly diffused over the entire floor surface. If the volume ratio is less than 0.1 and the amount of propellant is too large, the amount of the control component deposited on the floor surface will be insufficient. On the other hand, when the volume ratio exceeds 0.5, the spray particles settle down too quickly and the diffusivity over the entire floor becomes insufficient.
  • the aerosol for controlling ticks is a small amount of injection, so it is not necessary to dare to pay attention to the risk of fire, but it is also possible to adopt an aqueous formulation from the viewpoint of reducing the risk of fire as much as possible. ..
  • the amount of water contained in the undiluted aerosol solution is about 20 to 70 v/v%, and a small amount of nonionic surfactant as a solubilizing agent is used as long as it does not affect the spray pattern of spray particles. Agents may be added.
  • nonionic surfactants include ethers such as polyoxyethylene alkyl ethers, polyoxyethylene alkylphenyl ethers, polyoxyethylene polyoxypropylene alkyl ethers, polyoxyethylene alkylamino ethers, and polyethylene glycol.
  • ethers such as polyoxyethylene alkyl ethers, polyoxyethylene alkylphenyl ethers, polyoxyethylene polyoxypropylene alkyl ethers, polyoxyethylene alkylamino ethers, and polyethylene glycol.
  • mildew fungicides for fungi, antibacterial agents and bactericides, or fragrances, deodorants, stabilizers, antistatic agents, defoamers, Excipients and the like can also be appropriately mixed.
  • antifungal agents antibacterial agents and bactericides, hinokitiol, 2-mercaptobenzothiazole, 2-(4-thiazolyl)benzimidazole, 5-chloro-2-methyl-4-isothiazolin-3-one, triphorin, 3- Examples include methyl-4-isopropylphenol and ortho-phenylphenol.
  • fragrance orange oil, lemon oil, lavender oil, peppermint oil, eucalyptus oil, citronella oil, lime oil, yuzu oil, jasmine oil, cypress oil, green tea essential oil, limonene, ⁇ -pinene, linalool, geraniol
  • aromatic components such as phenylethyl alcohol, amyl cinnamic aldehyde, cumin aldehyde, and benzyl acetate, and perfume components including green leaf alcohol and green leaf aldehyde called “green scent”, but are not limited thereto.
  • Examples of the propellant used in the present invention include liquefied petroleum gas (LPG), liquefied gas such as dimethyl ether and hydrofluorocarbon, and compressed gas such as nitrogen gas, carbon dioxide gas, nitrous oxide, and compressed air. Alternatively, two or more kinds can be appropriately adopted.
  • LPG liquefied petroleum gas
  • the propellant may be appropriately determined in consideration of the adhering rate of the spray particles to the floor surface or the wall, but it is usually easy to use one mainly composed of LPG.
  • the propellant is preferably used after adjusting the gauge pressure (20° C.) to 0.1 to 0.7 MPa.
  • the aerosol for controlling pests and ticks is equipped with a fixed quantity injection valve with an injection volume of 1.0 to 5.0 mL each time, and is used for indoor fixed amount injection processing.
  • the injection volume of a fixed-quantity injection valve was 0.2 to 0.4 mL, but in the fixed-quantity injection valve used in the present invention, the required effective component amount can be injected with one push as the volume increases. ..
  • the shape of the nozzle, the nozzle, the container, and the like can be appropriately selected according to the application, the purpose of use, and the like. For example, it can be designed as a table-top type having a button that is pushed from above and ejecting and a nozzle that is directed obliquely upward, or can be designed as a portable small container.
  • the pest and mite control aerosol thus obtained is used, and the injection volume per injection is 1.0 to 5.0 mL, preferably 1.0 to 3.0 mL
  • the release amount of the control component to the air is set to 0.1 to 50 mg/m 3 , preferably 0.5 to 50 mg/m 3 . ..
  • Injection processing is performed in an indoor space with a volume of 18.8 to 33.3 m 3 (area 7.5 to 13.3 m 2 , height 2.2 to 3.0 m) corresponding to a room of 4.5 to 8 tatami mats.
  • the release amount of the control component into the air becomes 0.1 to 50 mg/m 3 .
  • the frequency of use of the pest and mite control aerosol once a day or two once a day, if application is performed so that the release amount of the control component is within the above range, crawling pests and/or indoor dust mites The control effect can be maintained for several days. In addition, it is possible to impart a controlling effect against flying insects by using a controlling component which is volatile at room temperature.
  • the pests of the present invention a method for controlling ticks, particularly, German cockroaches, American cockroaches, cockroaches such as black cockroaches, ants, bed bugs, bed bugs such as nettite white lice, beetle worms, weevil, beetle, dandelion, worm insects such as woodworm. , And is effective for controlling indoor dust mites such as A. niger, Dermatophagoides farinae, Dermatophagoides farinae, and Aedes mites.
  • crawling pests are not limited to mites, and pests that fly indoors and cause damage or discomfort to humans, for example, mosquitoes such as squid, Aedes albopictus, chironomids, house flies, butterfly flies, flies, and flies. It is also well applied to the control of various pests such as bees, bees and leafhoppers.
  • the pest and mite control method of the present invention and the pest and mite control aerosol will be described in more detail.
  • the present invention is not limited to these.
  • Example 1 Phenothrin 53 w/v% and metfluthrin 0.7 w/v% were dissolved in ethanol to prepare an aerosol stock solution. 12 mL of this aerosol stock solution (a) and 18 mL of liquefied petroleum gas (b) as a propellant were injected at a volume of 1.0 mL so that the volume ratio [a/(a+b)] of the aerosol stock solution would be 0.4. An aerosol container (pressure resistant container) equipped with a certain metering spray valve was pressure-filled to obtain an aerosol for controlling pests and mites of Example 1. The specific gravity of this undiluted aerosol solution was 0.93, and the ejection force of the present aerosol at an ejection distance of 5 cm was 26 gf. Further, ⁇ was 9.0.
  • the spray treatment was carried out by one-shot one shot with an aerosol for controlling pests and mites.
  • the adhesion rate (%) of the control component to the floor surface was calculated from the analysis result by gas chromatography described below and the amount of the control component released from the aerosol. As a result, 72% (that is, 72% of the released amount of the control component) of all the spray particles sprayed by this spraying process was settled and adhered over the entire floor surface by 1 hour after the spraying process. confirmed.
  • Example 1 aerosols for controlling various pests and mites shown in Table 1 were prepared.
  • the aerosols for controlling pests and mites of Examples 2 to 21 and 23 to 24 and Comparative Examples 1 and 3 to 4 were aerosol containers with a metering spray valve having an injection volume of 1.0 mL.
  • An aerosol container with a constant spray valve having a spray volume of 2.2 mL was used for the pest and mite control aerosol, and a fixed spray valve with a spray volume of 0.4 mL was used for the pest and mite control aerosol of Comparative Example 2.
  • An attached aerosol container was used.
  • test aerosol was directed slightly obliquely upward in the center of the room (spray volume: Examples 1 to 21, 23 to 24, Comparative Examples 1 and 3 to 1.0 mL, Example 22 2.2 mL, Comparative Example 2 0.4 mL) was injected. After being left to stand for 24 hours to be exposed to the drug, the glass plate together with the ring containing the test insect was moved to another room and fed, and after 24 hours, the mortality rate of the test insect was determined.
  • Mite repellent rate (%) [(number of invading mites in untreated area-number of invading mites in treated area) / number of invading mites in untreated area] x 100
  • Adhesion rate of control components to the floor A 20 x 20 cm glass plate is evenly installed in the entire room at 6 to 8 locations on the floor of a room (area 10 m 2 ) with a closed volume of 25 m 3 and the test aerosol is used. Was fired in the center of the room a little diagonally upward and one shot. One hour after the spraying treatment, all the glass plates were taken out, the attached control component was washed out with acetone, and analyzed by gas chromatography. Based on the obtained analysis values, the ratio (floor surface adhesion rate) of the control component settled and adhered to the floor surface to the theoretical total amount of the control component injection within one hour after the injection treatment was determined. In addition, regarding the control component attached to the glass plate, the dispersion between the glass plates was analyzed to evaluate the diffusion uniformity of the spray particles. The results are shown in four stages of A, B, C, and D in order from the one with good diffusion uniformity.
  • the sprayed particles spread almost uniformly over the entire floor surface, and up to 1 hour after spraying. It was confirmed that 60% or more of the control components settle and adhere to the floor surface. Further, when the pests of Examples 1 to 16 and 20 to 24 containing the compound for controlling crawling pests and the aerosol for controlling ticks are used as the less volatile control component, the crawling pests and indoor dust mites are used. It was confirmed that an excellent control effect was exerted on any of the above. When the pests of Examples 17 to 19 and the aerosols for controlling ticks, which are mixed with a compound for controlling ticks, are used as the hardly volatile control component, an excellent controlling effect for indoor dust mites can be obtained. confirmed.
  • Comparative Examples 1 to 4 a sufficient control effect was not obtained against both the crawling pests and indoor dust mites.
  • Comparative Example 1 since the aerosol containing only the room temperature volatile pyrethroid compound such as empentrin was used as the control component, the floor adhesion rate was reduced, and as a result, the control effect is considered to be low.
  • Comparative Example 2 since the fixed amount injection valve having an injection capacity of 0.4 mL was used, the control component to be injected did not reach the required amount with one push, and as a result, the control effect was considered to be low.
  • the pest and mite control method and the pest and mite control aerosol of the present invention can be used not only indoors but also for a wide range of pest and mite control.

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Abstract

Provided is a pest/mite control method that could maintain a control effect on crawling pests and indoor dust mites for several days simply by applying a pest/mite control aerosol once in an indoor space. The present invention provides a pest/mite control method for performing spray treatment employing a pest/mite control aerosol prepared by filling a propellant and an aerosol undiluted liquid containing a control component and an organic solvent in an aerosol container provided with a fixed-quantity spraying valve with which the spraying quantity per application is 1.0-5.0 ml. The control component is a low-volatility compound having a vapor pressure of less than 1×10-4 mmHg at 30ºC, the specific gravity of the aerosol undiluted liquid is 0.85-1.15, and the spraying force of the pest/mite control aerosol is 10-50 gf at a spraying distance of 5 cm.

Description

害虫、ダニ防除方法、及び害虫、ダニ防除用エアゾールPest and mite control method, and pest and mite control aerosol
　本発明は、防除成分及び有機溶剤を含有するエアゾール原液、並びに噴射剤を、一回当たりの噴射容量が１．０～５．０ｍＬである定量噴射バルブを備えたエアゾール容器に充填してなる害虫、ダニ防除用エアゾールを用いて噴射処理する害虫、ダニ防除方法、及び害虫、ダニ防除用エアゾールに関するものである。 The present invention is a pest obtained by filling an aerosol stock solution containing a control component and an organic solvent, and a propellant into an aerosol container equipped with a metered injection valve having an injection volume of 1.0 to 5.0 mL per injection. The present invention relates to a pest to be spray-treated with a tick control aerosol, a method for controlling ticks, and a pest and a tick control aerosol.
　床面や壁を徘徊するゴキブリ等の匍匐害虫や屋内塵性ダニ類を対象とし、匍匐害虫やダニ類が生息する場所や通り道に施用するタイプの殺虫剤としては、（１）燻煙剤、（２）全量噴射型エアゾール、（３）塗布型エアゾール、及び（４）ベイト剤が代表的で、それぞれ剤型上の特長を有している。 Targeting crawling pests such as cockroaches and indoor dust mites wandering around floors and walls, as a type of insecticide applied to places and passages where crawling pests and mites live, (1) smoking agents, Typical examples are (2) all-injection-type aerosol, (3) coating-type aerosol, and (4) bait agent, each of which has characteristics in terms of formulation.
　（１）燻煙剤や（２）全量噴射型エアゾールは、薬剤を一気に室内の隅々まで放散し、所定時間室内を密閉して薬剤濃度を高め、その間、人が入室できないことから、医薬品の範疇に該当する。これらの製剤は、一度施用すれば２～４週間、匍匐害虫や屋内塵性ダニ類に対する駆除効果が持続する反面、使用前の手順に手間がかかること、薬剤の安全性に格別留意する必要があること等から、手軽に頻繁に採用される剤型とは言い難い。 (1) Smoke agent and (2) Full-volume injection type aerosol disperse the drug all over the room at a stretch, and seal the room for a predetermined time to increase the drug concentration, and during that time, people cannot enter the room. It falls into the category. Once applied, these preparations will continue to be effective in exterminating crawling pests and indoor dust mites for 2 to 4 weeks, but require time-consuming pre-use procedures and special attention must be paid to drug safety. For this reason, it is hard to say that the dosage form is easily and frequently adopted.
　一方、局所的に面処理する（３）塗布型エアゾールや、点処理の（４）ベイト剤は、人体に対する作用が緩和な医薬部外品に該当し、（１）燻煙剤や（２）全量噴射型エアゾールに較べると使い易いが、空間処理でないため薬剤と害虫やダニ類との接触効率が劣り、必ずしも効率的な駆除方法を提供できるものでもない。 On the other hand, locally applied surface treatment (3) application type aerosol and point treatment (4) bait agent correspond to quasi-drugs having a mild effect on the human body, and (1) smoke agent and (2) It is easier to use than full-blown aerosols, but since it is not a space treatment, the contact efficiency between the drug and pests and mites is poor, and it is not always possible to provide an efficient extermination method.
　このように、従来、空間処理でありながら医薬部外品に該当する匍匐害虫や屋内塵性ダニ類用防除剤の開発は困難と考えられてきた。 Thus, conventionally, it has been considered difficult to develop a control agent for crawling pests and indoor dust mites that is a quasi drug even though it is a spatial treatment.
　ところで、特許文献１は、殺虫成分および溶剤を含む殺虫液を室内空間、収納空間等の空間内に蒸散させて匍匐害虫を駆除する方法であって、溶剤として特定の構造を有する化合物を用い、空間に粒子径の小さい殺虫液微粒子が浮遊し続けるべく、ピエゾ式噴霧器により殺虫液を少量ずつ時間をかけて蒸散させる匍匐害虫駆除方法を開示する。この特許文献１の方法は、液体電気蚊取りのように、微量の薬剤を継続して長時間にわたり空間に放散し、ゴキブリを駆除することを提案したものであるが、蚊に較べて数十倍薬剤に強いゴキブリを対象とする以上、強力な殺虫成分を使用せざるを得ず、人体に対する安全性の懸念が避けられない。 By the way, Patent Document 1 is a method for exterminating crawling pests by evaporating an insecticidal liquid containing an insecticidal component and a solvent into a space such as an indoor space or a storage space, using a compound having a specific structure as a solvent, Disclosed is a method for exterminating crawling insect pests, which comprises evaporating the insecticidal liquid little by little with a piezo sprayer over a period of time so that the insecticidal liquid fine particles having a small particle diameter continue to float in the space. The method of Patent Document 1 proposes to continuously disperse a small amount of a drug into a space for a long time and exterminate cockroaches like liquid electric mosquito repellent, but it is several tens of times that of mosquitoes. Since it is targeted at the cockroaches that are strong against the drug, it is unavoidable to use a powerful insecticidal component, and thus there is an unavoidable safety concern for the human body.
　本発明者らは、先に、空間処理剤であって、医薬部外品に該当する匍匐害虫や屋内塵性ダニ類用防除剤を開発するにあたり、（１）燻煙剤や（２）全量噴射型エアゾールのような２～４週間に一度の頻度で使用される製剤ではなく、１回定量噴霧処理すれば実用条件下で数日間防除効果が持続する、即ち基本的に１～２日に１回使用する製剤であって、人が居る状況下でも使用可能な安全性の高い製剤を目指して鋭意検討を行った。その結果、匍匐害虫や屋内塵性ダニ類のみならず、噴霧当日は飛翔害虫にも有効で、極めて有用な「害虫、ダニ防除方法」（特許文献２参照）を発明した。なお、この発明は、飛翔害虫に対する実用的な駆除効果をも実現するべく、エアゾールの噴射特性として、噴射後の噴霧粒子が、浮遊性粒子と、壁面等への付着並びに床面への沈降に関わる付着性粒子とに形成されるとともに、好ましくは、全体の噴霧粒子のうちの３０～８０％が噴射処理１時間後までに壁面等に付着するか、もしくは床面に沈降するように設計した。また、特許文献２の発明当時、定量噴射バルブの噴射容量としては０．２～０．４ｍＬが一般的で、当該製剤は１回の処理において数プッシュ（噴射ボタンの押下）することが基本とされた。 The present inventors previously developed a space treatment agent, which is a quasi-drug-related non-pharmaceutical control agent for crawling pests and indoor dust mites, (1) smoking agent and (2) total amount Rather than a formulation that is used once every 2 to 4 weeks, such as a spray type aerosol, once a fixed amount spray treatment, the control effect lasts for several days under practical conditions, that is, basically 1 to 2 days. As a formulation to be used once, a thorough study was conducted aiming at a highly safe formulation that can be used even in the presence of people. As a result, the inventors have invented a very useful “pest and mite control method” (see Patent Document 2) that is effective not only for crawling pests and indoor dust mites but also for flying pests on the day of spraying. In addition, in order to realize a practical extermination effect against flying pests, the present invention has a spraying property of an aerosol, in which sprayed particles after spraying are buoyant particles, adhere to a wall surface and settle to a floor surface. It is designed so that 30 to 80% of all the spray particles adhere to the wall surface or the like or settle to the floor surface by 1 hour after the injection treatment, in addition to the formation of the adhesive particles involved. .. In addition, at the time of the invention of Patent Document 2, the injection volume of the constant-quantity injection valve is generally 0.2 to 0.4 mL, and it is basically necessary to push the preparation several times (press the injection button) in one treatment. Was done.
　一方、特許文献３には、定量噴射バルブを用いる匍匐害虫駆除用エアゾール製品及び匍匐害虫駆除方法が開示されている。このエアゾール製品は、エアゾール容器に収容される噴射剤の配合比率を高めるとともに、有効成分を溶解する溶剤の蒸気圧を低めにし、エアゾール容器から噴射された粒子を形成している溶剤の蒸発速度を遅くすることで、当該粒子が屋内の隙間の奥まで飛散するようにしたことを特徴とする。即ち、特許文献３の方法は、定量噴射処理であるとしても（３）塗布型エアゾールによる局所処理に該当し、空間処理に当たらない。従って、一部の隙間において局所的に高い駆除効果が得られたとしても、屋内全体にわたって匍匐害虫を効率的に駆除できるわけではない。 On the other hand, Patent Document 3 discloses an aerosol product for exterminating crawling pests and a method for exterminating crawling pests using a constant-quantity injection valve. This aerosol product increases the mixing ratio of the propellant contained in the aerosol container, lowers the vapor pressure of the solvent that dissolves the active ingredient, and increases the evaporation rate of the solvent that forms the particles injected from the aerosol container. It is characterized in that the particles are scattered to the depths of the indoor gap by slowing down. That is, the method of Patent Document 3 corresponds to (3) the local treatment by the coating type aerosol even if it is the quantitative injection treatment, and does not correspond to the spatial treatment. Therefore, even if a high extermination effect is locally obtained in a part of the gap, it is not possible to exterminate the crawling pest efficiently in the entire indoor area.
特開２００９－１４３８６８号公報JP, 2009-143868, A 特許第５５１７１２２号公報Japanese Patent No. 5517122 特開２０１８－１２６７６号公報JP, 2008-12676, A
　かかる状況を鑑み、本発明者らは、特許文献２に基づく空間定量噴射処理が最も効率的な害虫、ダニ防除方法であるとの認識に則り、それの利便性を改善するとともに、特に匍匐害虫や屋内塵性ダニ類に対する更なる効能アップを目指して検討を行った。まず、近年開発されている噴射容量が１．０～５．０ｍＬの定量噴射バルブを採用し、必要な有効成分量をワンプッシュで噴射可能とした。そのうえで、空間処理において、匍匐害虫のなかでも特にゴキブリ等に対する防除効果をアップさせるには、噴射後の噴霧粒子を、処理空間に浮遊する浮遊性粒子と、処理空間内の露出部に付着する付着性粒子として形成するだけでは足りず、付着性粒子を特許文献２の噴射特性と比較してより一層優占的となし、更に、付着性粒子のなかでも壁面等への付着よりも床面への沈降に関わる付着性粒子の比率を高めることが肝要との結論に達した。そして、本発明者らは、エアゾール原液の比重とエアゾールの噴射力が、沈降に関わる付着性粒子の挙動を決定する重要なファクターであることを知見し、試行錯誤を重ね試験を繰返し行った結果、前記エアゾール原液の比重とエアゾールの噴射力につき最適な範囲を特定することによって本発明を完成するに至ったのである。 In view of such a situation, the present inventors have found that the spatial quantitative injection treatment based on Patent Document 2 is the most efficient pest and mite control method, and improve the convenience thereof, and in particular, the crawling pest. The study was conducted with the aim of further improving the efficacy against indoor dust mites. First, a recently developed quantitative injection valve with an injection capacity of 1.0 to 5.0 mL was used to enable injection of the required amount of active ingredient with one push. In addition, in the space treatment, in order to improve the control effect against cockroaches among the crawling pests, in order to improve the control effect, the sprayed particles after injection are floating particles floating in the processing space and the adhesion that adheres to the exposed part in the processing space. It is not enough to form the adhering particles as the adhering particles, and the adhering particles are more predominant as compared with the jetting characteristics of Patent Document 2, and further, among the adhering particles, the adhering particles reach the floor surface rather than adhering to the wall surface etc. It was concluded that it is essential to increase the ratio of adhesive particles involved in the sedimentation of the. Then, the present inventors have found that the specific gravity of the aerosol stock solution and the jetting force of the aerosol are important factors that determine the behavior of the adhesive particles involved in sedimentation, and the results of repeated trial and error tests The present invention has been completed by specifying the optimum range for the specific gravity of the aerosol stock solution and the ejection force of the aerosol.
　本発明の目的は、容量が１．０～５．０ｍＬの定量噴射バルブを備えた害虫、ダニ防除用エアゾールを屋内空間でワンプッシュするだけで匍匐害虫や屋内塵性ダニ類に対する防除効果を数日間持続させ得る害虫、ダニ防除方法、及び害虫、ダニ防除用エアゾールを提供することにある。 An object of the present invention is to control pests and mite pests and indoor dust mites with a single push of an aerosol for controlling pests and mites, which is equipped with a quantitative injection valve with a capacity of 1.0 to 5.0 mL. It is intended to provide a pest that can be maintained for a day, a method for controlling ticks, and an aerosol for controlling pests and ticks.
　本発明は、以下の構成が上記目的を達成するために優れた効果を奏することを見出したものである。
〔１〕防除成分及び有機溶剤を含有するエアゾール原液、並びに噴射剤を、一回当たりの噴射容量が１．０～５．０ｍＬである定量噴射バルブを備えたエアゾール容器に充填してなる害虫、ダニ防除用エアゾールを用いて噴射処理する害虫、ダニ防除方法であって、
　前記防除成分は、３０℃における蒸気圧が１×１０－４ｍｍＨｇ未満である難揮散性化合物であり、
　前記エアゾール原液の比重は、０．８５～１．１５であり、
　前記害虫、ダニ防除用エアゾールの噴射力は、噴射距離５ｃｍにおいて１０～５０ｇｆであり、
　前記噴射処理において屋内空間の気中に、前記防除成分の放出量が０．１～５０ｍｇ／ｍ３となるように前記エアゾール原液を噴射し、噴射から１時間後までに前記防除成分の６０％以上を前記屋内空間の床面全体に拡散させて付着させる害虫、ダニ防除方法。
〔２〕前記害虫、ダニ防除用エアゾールは、前記エアゾール原液の充填量をａ、前記噴射剤の充填量をｂ、前記エアゾール原液の比重をＳ、前記害虫、ダニ防除用エアゾールの噴射力をＦとしたとき、以下の式（１）：
　　δ　＝　［ａ／（ａ＋ｂ）］　×　Ｓ２　×　Ｆ　・・・　（１）
で定義するδが１．０～３０の範囲にあるように構成されている〔１〕に記載の害虫、ダニ防除方法。
〔３〕前記害虫、ダニ防除用エアゾールは、以下の式（２）：
　　０．１　≦　［ａ／（ａ＋ｂ）］　≦　０．５　・・・　（２）
を満たすように構成されている〔２〕に記載の害虫、ダニ防除方法。
〔４〕前記害虫、ダニ防除用エアゾールは、以下の式（３）：
　　３．０　≦　δ　≦　１５　・・・　（３）
を満たすように構成されている〔２〕又は〔３〕に記載の害虫、ダニ防除方法。
〔５〕前記難揮散性化合物は、フェノトリン、シフェノトリン、ペルメトリン、シペルメトリン、シフルトリン、ビフェントリン、フェンプロパトリン、トラロメトリン、エトフェンプロックス、及びジノテフランからなる群から選択される少なくとも１種の匍匐害虫防除用化合物である〔１〕～〔４〕の何れか一つに記載の害虫、ダニ防除方法。
〔６〕前記難揮散性化合物は、アミドフルメト、安息香酸ベンジル、サリチル酸フェニル、サリチル酸ベンジル、セバシン酸ジブチル、セバシン酸ジプロピル、アジピン酸ジブチル、フタル酸ジエチル、フタル酸ジブチル、及びｐ－メンタン－３，８－ジオールからなる群から選択される少なくとも１種のダニ防除用化合物である〔１〕～〔４〕の何れか一つに記載の害虫、ダニ防除方法。
〔７〕前記有機溶剤は、炭素数が２～３の低級アルコールである〔１〕～〔６〕の何れか一つに記載の害虫、ダニ防除方法。
〔８〕前記屋内空間の床面の面積は、７．５～２６．６ｍ２である〔１〕～〔７〕の何れか一つに記載の害虫、ダニ防除方法。
〔９〕防除成分及び有機溶剤を含有するエアゾール原液、並びに噴射剤を、一回当たりの噴射容量が１．０～５．０ｍＬである定量噴射バルブを備えたエアゾール容器に充填してなる害虫、ダニ防除用エアゾールであって、
　前記防除成分は、３０℃における蒸気圧が１×１０－４ｍｍＨｇ未満である難揮散性化合物であり、
　前記エアゾール原液の比重は、０．８５～１．１５であり、
　前記害虫、ダニ防除用エアゾールの噴射力は、噴射距離５ｃｍにおいて１０～５０ｇｆであり、
　前記定量噴射バルブを介した一回の噴射処理により屋内空間の気中に、前記防除成分の放出量が０．１～５０ｍｇ／ｍ３となるように前記エアゾール原液を噴射した場合、噴射から１時間後までに前記防除成分の６０％以上が、前記屋内空間の床面全体に拡散して付着する害虫、ダニ防除用エアゾール。 The present invention has found that the following configurations have excellent effects for achieving the above object.
[1] A pest obtained by filling an aerosol stock solution containing a control component and an organic solvent, and a propellant into an aerosol container equipped with a metered injection valve having an injection volume of 1.0 to 5.0 mL per time. A pest to be spray-treated with a tick control aerosol, a method for controlling ticks,
The control component is a hardly volatile compound having a vapor pressure at 30° C. of less than 1×10 −4 mmHg,
The specific gravity of the aerosol stock solution is 0.85 to 1.15,
The spray force of the pest and mite control aerosol is 10 to 50 gf at a spray distance of 5 cm,
In the injection process, the aerosol stock solution is injected into the air of the indoor space so that the release amount of the control component is 0.1 to 50 mg/m 3, and 60% of the control component is injected one hour after the injection. A method for controlling pests and ticks, wherein the above is diffused and attached to the entire floor surface of the indoor space.
[2] The pest and mite control aerosol has a filling amount of the aerosol undiluted solution a, a filling amount of the propellant b, a specific gravity of the aerosol undiluted solution S, and a spraying force of the pest and tick controlling aerosol F. Then, the following equation (1):
δ=[a/(a+b)]×S 2 ×F (1)
The method for controlling pests and mites according to [1], wherein δ defined in 1. is in the range of 1.0 to 30.
[3] The aerosol for controlling pests and mites has the following formula (2):
0.1 ≤ [a/(a+b)] ≤ 0.5 (2)
The method for controlling pests and mites according to [2], which is configured to satisfy the above.
[4] The aerosol for controlling pests and mites has the following formula (3):
3.0 ≤ δ ≤ 15 (3)
The method for controlling pests and mites according to [2] or [3], which is configured to satisfy the above.
[5] The sparingly volatile compound is at least one crawling insect pest control selected from the group consisting of phenothrin, cyphenothrin, permethrin, cypermethrin, cyfluthrin, bifenthrin, fenpropatrine, tralomethrin, etofenprox, and dinotefuran. The method for controlling pests and mites according to any one of [1] to [4], which is a compound for use.
[6] The sparingly volatile compound is amidoflumet, benzyl benzoate, phenyl salicylate, benzyl salicylate, dibutyl sebacate, dipropyl sebacate, dibutyl adipate, diethyl phthalate, dibutyl phthalate, and p-menthane-3,8. -The method for controlling pests and mites according to any one of [1] to [4], which is at least one tick controlling compound selected from the group consisting of diols.
[7] The method for controlling pests and mites according to any one of [1] to [6], wherein the organic solvent is a lower alcohol having 2 to 3 carbon atoms.
[8] The method for controlling pests and mites according to any one of [1] to [7], wherein the floor area of the indoor space is 7.5 to 26.6 m 2 .
[9] A pest obtained by filling an aerosol stock solution containing a control component and an organic solvent, and a propellant into an aerosol container equipped with a metered injection valve having an injection volume of 1.0 to 5.0 mL per time. An aerosol for controlling ticks,
The control component is a hardly volatile compound having a vapor pressure at 30° C. of less than 1×10 −4 mmHg,
The specific gravity of the aerosol stock solution is 0.85 to 1.15,
The spray force of the pest and mite control aerosol is 10 to 50 gf at a spray distance of 5 cm,
When the aerosol stock solution is injected into the air of the indoor space by a single injection process through the quantitative injection valve so that the release amount of the control component becomes 0.1 to 50 mg/m 3 , An aerosol for controlling pests and mites, in which 60% or more of the control component diffuses and adheres to the entire floor surface of the indoor space by the lapse of time.
　本発明の害虫、ダニ防除方法、及び害虫、ダニ防除用エアゾールによれば、難揮散性化合物を含む特定の害虫、ダニ防除用エアゾールを屋内空間でワンプッシュして噴射処理するだけで、その処理区域において特に匍匐害虫や屋内塵性ダニ類に対する防除効果を数日間持続させることができる。利便的かつ効果的な害虫、ダニ防除方法、及び害虫、ダニ防除用エアゾールを提供するので、極めて実用的である。 According to the pests of the present invention, a method for controlling ticks, and pests, and a mite control aerosol, a specific pest containing a hardly volatile compound, an aerosol for controlling a ticks is just one push in an indoor space, and the treatment is carried out. Especially in the area, the control effect against the crawling pests and indoor dust mites can be maintained for several days. It is extremely practical because it provides a convenient and effective method for controlling pests and ticks, and an aerosol for controlling pests and ticks.
　本発明では、防除成分として、３０℃における蒸気圧が１×１０－４ｍｍＨｇ未満である難揮散性化合物が使用される。かかる防除成分は、本発明の害虫、ダニ防除用エアゾールを屋内空間でワンプッシュする噴射処理後、主に付着性粒子として床面に沈降し、その屋内空間において特に匍匐害虫や屋内塵性ダニ類に対して優れた防除効果を示す。なお、本発明では、ノックダウン効果や致死効果に基づく駆除効果に加え、忌避効果を合わせて防除効果と呼ぶ。駆除効果が低くても十分な忌避効果があれば、実用上、防除が達せられる場面も多い。 In the present invention, a fugitive compound having a vapor pressure at 30° C. of less than 1×10 −4 mmHg is used as a control component. Such a controlling component is the insect pest of the present invention, after the spray treatment of one-push aerosol for controlling ticks in the indoor space, mainly settles on the floor as adherent particles, especially in the indoor space crawling pests and indoor dust mites It shows an excellent control effect against. In addition, in the present invention, in addition to the exterminating effect based on the knockdown effect and the lethal effect, the repelling effect is collectively referred to as a controlling effect. Even if the extermination effect is low, if there is a sufficient repellent effect, there are many cases where the control can be achieved in practice.
　即ち、本発明は、特許文献２に基づく空間定量噴射処理が最も効率的な害虫、ダニ防除方法であるとの認識に則り、それの利便性を改善するとともに、特に匍匐害虫や屋内塵性ダニ類に対する更なる効能アップを目指したものである。まず、近年開発されている容量が１．０～５．０ｍＬの定量噴射バルブを採用し、必要な有効成分量をワンプッシュで噴射可能とした。そのうえで、空間処理において、匍匐害虫のなかでも特にゴキブリ等に対する防除効果をアップさせるには、噴射後の噴霧粒子から形成される浮遊性粒子と付着性粒子のうち付着性粒子の優占度を高め、更に、付着性粒子のなかでも壁面等への付着よりも床面へ沈降する比率を高めることが肝要との方向性に基づき達成されたのである。なお、本発明の付着性粒子は、沈降に至る過程において隙間や物陰にも進入するため、防除成分としてピレスロイド系化合物を用いた場合には、ゴキブリ等が隙間や物陰から飛び出すフラッシング効果も十分期待し得るものである。 That is, the present invention is based on the recognition that the spatial quantitative injection treatment based on Patent Document 2 is the most effective pest and mite control method, and improves the convenience thereof, and in particular, crawling pests and indoor dust mites. It is aimed at further improving the efficacy against various kinds. First, a metered-quantity injection valve with a capacity of 1.0 to 5.0 mL, which has been developed in recent years, was adopted to make it possible to inject the required amount of active ingredient with one push. On top of that, in space treatment, in order to improve the control effect especially against cockroaches among crawling pests, in order to increase the predominance of adherent particles among floating particles and adherent particles formed from sprayed particles after injection. Furthermore, it has been achieved based on the direction that it is important to increase the ratio of the adherent particles settling on the floor surface rather than adhering to the wall surface or the like. In addition, since the adhesive particles of the present invention also enter into the gaps and the shade in the process leading to sedimentation, when a pyrethroid compound is used as a control component, a flushing effect of cockroaches jumping out from the gaps or the shade is also expected sufficiently. It is possible.
　本発明で用いる難揮散性の防除成分としては、主にゴキブリに代表される匍匐害虫を防除するための匍匐害虫防除用化合物、及び／又は主に屋内塵性ダニ類を防除するためのダニ防除用化合物を用いることができる。匍匐害虫防除用化合物としては、フェノトリン、シフェノトリン、ペルメトリン、シペルメトリン、シフルトリン、ビフェントリン、フェンプロパトリン、トラロメトリン、エトフェンプロックス、及びイミプロトリン等のピレスロイド系化合物、シラフルオフェン等のケイ素系化合物、ジクロルボス、及びフェニトロチオン等の有機リン系化合物、プロポクスル等のカーバメート系化合物、ジノテフラン、イミダクロプリド、及びクロチアニジン等のネオニコチノイド系化合物、その他にフィプロニル、インドキサカルブ等があげられる。これらの中では、フェノトリン、シフェノトリン、ペルメトリン、シペルメトリン、シフルトリン、ビフェントリン、フェンプロパトリン、トラロメトリン、エトフェンプロックス、及びジノテフランが好ましい。なお、ピレスロイド系化合物の酸成分やアルコール部分において、不斉炭素に基づく光学異性体や幾何異性体が存在する場合、それらの各々や任意の混合物も本発明に包含されることはもちろんである。 As the volatile control component used in the present invention, a crawling pest control compound for controlling crawling pests typified by cockroaches, and/or a tick control mainly for controlling indoor dust mites Compounds for use can be used. Examples of compounds for controlling crawling pests include phenothrin, cyphenothrin, permethrin, cypermethrin, cyfluthrin, bifenthrin, fenpropatrine, tralomethrin, etofenprox, and pyrethroid compounds such as imiprothrin, silafluofen and other silicon compounds, dichlorvos, and the like. Examples include organophosphorus compounds such as fenitrothion, carbamate compounds such as propoxur, dinotefuran, imidacloprid, and neonicotinoid compounds such as clothianidin, and fipronil and indoxacarb. Among these, phenothrin, cyphenothrin, permethrin, cypermethrin, cyfluthrin, bifenthrin, fenpropatrine, tralomethrin, etofenprox, and dinotefuran are preferable. In the case where the acid component or alcohol moiety of the pyrethroid compound has optical isomers or geometric isomers based on asymmetric carbon, it goes without saying that each of them and any mixture thereof are also included in the present invention.
　ダニ防除用化合物としては、アミドフルメト、安息香酸ベンジル、サリチル酸フェニル、サリチル酸ベンジル、セバシン酸ジブチル、セバシン酸ジプロピル、アジピン酸ジブチル、フタル酸ジエチル、フタル酸ジプロピル、フタル酸ジブチル、ｐ－メンタン－３，８－ジオール、３－ヨード－２－プロピニルブチルカーバメート、フェノトリン、及びディート等があげられるが、アミドフルメト、安息香酸ベンジル、サリチル酸フェニル、サリチル酸ベンジル、セバシン酸ジブチル、セバシン酸ジプロピル、アジピン酸ジブチル、フタル酸ジエチル、フタル酸ジブチル、ｐ－メンタン－３，８－ジオール、フェノトリン、及びディートが好適である。 Examples of compounds for controlling ticks include amidoflumet, benzyl benzoate, phenyl salicylate, benzyl salicylate, dibutyl sebacate, dipropyl sebacate, dibutyl adipate, diethyl phthalate, dipropyl phthalate, dibutyl phthalate, p-menthane-3,8. Examples thereof include diol, 3-iodo-2-propynylbutyl carbamate, phenothrin, and diet. Amidoflumet, benzyl benzoate, phenyl salicylate, benzyl salicylate, dibutyl sebacate, dipropyl sebacate, dibutyl adipate, diethyl phthalate. Preferred are dibutyl phthalate, p-menthane-3,8-diol, phenothrin, and diet.
　本発明の害虫、ダニ防除方法は、防除成分及び有機溶剤を含有するエアゾール原液を少量一定量空間噴射する。エアゾール原液中の防除成分含有量は、１．０～７０ｗ／ｖ％程度であることが好ましい。エアゾール原液中の防除成分含有量が１．０ｗ／ｖ％未満であると所望の防除効果が得られず、７０ｗ／ｖ％を超えるとエアゾール原液の液性安定化の点で困難を伴う。 According to the method for controlling pests and mites of the present invention, a small amount of a fixed amount of an aerosol stock solution containing a control component and an organic solvent is sprayed in space. The content of the controlling component in the undiluted aerosol solution is preferably about 1.0 to 70 w/v %. If the content of the control component in the aerosol stock solution is less than 1.0 w/v%, the desired control effect cannot be obtained, and if it exceeds 70 w/v%, there is difficulty in stabilizing the liquid properties of the aerosol stock solution.
　本発明では、上記難揮散性の防除成分に加え、空間噴射処理後、噴霧粒子のある程度が気中に浮遊残存し、飛翔害虫に対しても防除効果を発揮し得るように、３０℃における蒸気圧が２×１０－４ｍｍＨｇ以上、１×１０－２ｍｍＨｇ未満である常温揮散性の防除成分を加えてもよい。かかる常温揮散性防除成分としては、例えば、メトフルトリン、プロフルトリン、トランスフルトリン、エムペントリン、テラレスリン、及びフラメトリン等があげられる。常温揮散性防除成分は、難揮散性の防除成分と共に一部床面や壁面に付着すると、匍匐害虫及び／又は屋内塵性ダニ類に対する防除効果を相乗的に高め得ることが認められている。なお、常温揮散性防除成分には、蒸気圧や安定性、基礎殺虫効力等を考慮すると、メトフルトリン、プロフルトリン、及びトランスフルトリンが好ましく、これらの化合物の酸成分やアルコール部分において、不斉炭素に基づく光学異性体や幾何異性体が存在する場合、それらの各々や任意の混合物も本発明に包含されることはもちろんである。 In the present invention, in addition to the above-mentioned hardly volatilizing control component, after spraying in space, some of the spray particles remain floating in the air, and vapor at 30° C. may be exerted as a control effect against flying pests. A room temperature volatile control component having a pressure of 2×10 −4 mmHg or more and less than 1×10 −2 mmHg may be added. Examples of such a room temperature volatile control component include metofluthrin, profluthrin, transfluthrin, empentrin, terrarethrin, and flamethrin. It has been recognized that the room-temperature volatile control component can synergistically enhance the control effect against crawling pests and/or indoor dust mites when partly attached to the floor surface or the wall surface together with the difficult-volatile control component. In addition, the room temperature volatile control component, considering the vapor pressure and stability, basic insecticidal efficacy, etc., metofluthrin, profluthrin, and transfluthrin are preferable, in the acid component and alcohol portion of these compounds, asymmetric carbon When the optical isomers and geometrical isomers based on them exist, each of them and any mixture thereof are of course included in the present invention.
　本発明では、上記難揮散性の防除成分を溶解するために有機溶剤を配合し、エアゾール原液を構成する。かかる有機溶剤としては、炭素数が２～３の低級アルコール、ノルマルパラフィンやイソパラフィンのような炭化水素系溶剤、ミリスチン酸イソプロピル（ＩＰＭ）やラウリン酸ヘキシルのようなエステル系溶剤、炭素数３～１０のグリコールエーテル系溶剤、ケトン系溶剤等があげられるが、エタノールやイソプロパノール（ＩＰＡ）に代表される炭素数が２～３の低級アルコールが好ましい。 In the present invention, an aerosol stock solution is formed by mixing an organic solvent in order to dissolve the above-mentioned volatile control components. Examples of the organic solvent include lower alcohols having 2 to 3 carbon atoms, hydrocarbon solvents such as normal paraffin and isoparaffin, ester solvents such as isopropyl myristate (IPM) and hexyl laurate, and 3 to 10 carbon atoms. The glycol ether-based solvent, the ketone-based solvent and the like are mentioned, but a lower alcohol having 2 to 3 carbon atoms represented by ethanol or isopropanol (IPA) is preferable.
　本発明の害虫、ダニ防除方法は、難揮散性の防除成分を含む害虫、ダニ防除用エアゾールを用い、一回当たりの噴射容量を１．０～５．０ｍＬとして屋内空間に噴射処理を行うことにより、その処理区域において匍匐害虫及び／又は屋内塵性ダニ類に対する防除効果を数日間持続させるものである。屋内空間のサイズは、４．５～８畳の部屋に相当する容積１８．８～３３．３ｍ３（面積７．５～１３．３ｍ２、高さ２．２～３．０ｍ）であることが好ましい。 The pest and mite control method of the present invention uses an aerosol for controlling pests and mites, which contains a volatile control component, and sprays the indoor space with a spray volume of 1.0 to 5.0 mL. Therefore, the control effect against the creeping insect pests and/or indoor dust mites in the treated area is maintained for several days. The size of the indoor space should be a volume of 18.8-33.3m 3 (area 7.5-13.3m 2 , height 2.2-3.0m) that corresponds to a room of 4.5-8 tatami mats. Is preferred.
　噴射後の噴霧粒子は、処理空間に浮遊する浮遊性粒子、もしくは処理空間内の露出部に付着する付着性粒子として形成されるが、本発明者らは、付着性粒子を一層優占的となし、更に、付着性粒子のなかでも壁面等への付着よりも床面への沈降に関わる付着性粒子の比率を高めるための検討を行った。その結果、本発明者らは、エアゾール原液の比重とエアゾールの噴射力が、沈降に関わる付着性粒子の挙動を決定する重要なファクターであることを知見し、それらの最適な範囲を特定するに至った。即ち、エアゾール原液の比重が０．８５～１．１５、好ましくは０．８９～１．１０であり、噴射処理の噴射力が噴射距離５ｃｍにおいて１０～５０ｇｆ、好ましくは１５～３５ｇｆであれば、噴射から１時間後までに防除成分の６０％以上が屋内空間の床面全体にわたり沈降・付着し、匍匐害虫、及びダニに対する優れた防除効果を奏し得ることを確認できたのである。なお、防除成分が「床面全体にわたり沈降・付着すること」について、防除成分が実際に床面全体にわたって沈降・付着しているかをその都度確認する必要はなく、エアゾールが処理空間内において本発明の趣旨に沿った態様で噴射されていれば、噴射された防除成分の床面に対する沈降・付着状態に多少の分布や偏りがあったとしても、防除成分が床面全体にわたり沈降・付着しているものと見做すことができ、このように見做しても実用上差支えはない。エアゾール原液の比重が０．８５未満であると、噴霧粒子の床面への付着量が不足する傾向があり、エアゾール原液の比重が１．１５を超えると、逆に噴霧粒子の沈降が速やか過ぎて床面全体への拡散性が不十分となる。また、噴射処理の噴射力が１０ｇｆ未満であると、噴射力が不足して床面全体への拡散性が不十分となる傾向があり、噴射力が５０ｇｆを越えても良好な拡散性が得られない。なお、エアゾールの噴射力は、エアゾール原液の処方、エアゾールの内圧、噴口の形状等を変更することで、適宜調整することができる。 The sprayed particles after jetting are formed as floating particles floating in the processing space or adhesive particles adhering to an exposed portion in the processing space. However, the present inventors have made the adhesive particles more dominant. None, and further, among the adhesive particles, a study was conducted to increase the ratio of the adhesive particles involved in sedimentation to the floor surface rather than to the wall surface. As a result, the present inventors have found that the specific gravity of the aerosol stock solution and the jetting force of the aerosol are important factors that determine the behavior of the adhesive particles involved in sedimentation, and to identify their optimum range. I arrived. That is, if the specific gravity of the aerosol stock solution is 0.85 to 1.15, preferably 0.89 to 1.10, and the injection force of the injection treatment is 10 to 50 gf, preferably 15 to 35 gf at an injection distance of 5 cm, It was confirmed that 60% or more of the control components settled and adhered to the entire floor surface of the indoor space by 1 hour after the injection, and an excellent control effect against crawling pests and mites could be achieved. Regarding the "precipitation and adhesion of the control component over the entire floor surface", it is not necessary to check each time whether the control component actually deposits or adheres over the entire floor surface. If it is sprayed in a manner in line with the purpose of, even if there is some distribution or deviation in the settling/adhesion state of the sprayed control component to the floor surface, the control component will settle or adhere to the entire floor surface. It can be regarded as a living thing, and there is no practical problem even if it is regarded as such. If the specific gravity of the aerosol concentrate is less than 0.85, the amount of spray particles attached to the floor tends to be insufficient, and if the specific gravity of the aerosol concentrate exceeds 1.15, the settling of the spray particles will be too fast. As a result, the diffusion property over the entire floor surface becomes insufficient. Further, if the injection force of the injection process is less than 10 gf, the injection force tends to be insufficient and the diffusivity over the entire floor surface tends to be insufficient. Even if the injection force exceeds 50 gf, good diffusivity can be obtained. I can't. The spraying force of the aerosol can be appropriately adjusted by changing the formulation of the undiluted aerosol solution, the internal pressure of the aerosol, the shape of the injection port, and the like.
　更に、害虫、ダニ防除用エアゾールは、エアゾール原液の充填量をａ、噴射剤の充填量をｂ、エアゾール原液の比重をＳ、害虫、ダニ防除用エアゾールの噴射力をＦとしたとき、以下の式（１）：
　　δ　＝　［ａ／（ａ＋ｂ）］　×　Ｓ２　×　Ｆ　・・・　（１）
で定義するδが１．０～３０の範囲にあることが好ましく、３．０～１５の範囲にあることがより好ましい。 Further, the pest and mite control aerosol has the following formula, where a is the amount of the undiluted solution of the aerosol, b is the amount of the propellant, S is the specific gravity of the undiluted aerosol solution, and F is the ejection force of the pest and mite controlling aerosol. Formula (1):
δ=[a/(a+b)]×S 2 ×F (1)
It is preferable that δ defined in step 1 is in the range of 1.0 to 30, and more preferably in the range of 3.0 to 15.
　δが１．０～３０の範囲にあれば、噴霧粒子が沈降したときに十分な量の防除成分が床面全体へ均一に拡散することで、好ましい防除効果が得られる。防除成分が床面全体へ均一に拡散するのは、害虫、ダニ防除用エアゾールから噴射される噴霧粒子の初速が適切なものとなり、噴射後、速やかに噴霧粒子が屋内空間の隅々まで行きわたるためと考えられる。δが１．０未満であると、防除成分の床面への付着量が不足する場合がある。一方、δが３０を越えると、床面全体への拡散性が不十分となる場合がある。そのため、δが１．０～３０の範囲を外れると満足のいく防除効果を奏し得ない虞がある。 When δ is in the range of 1.0 to 30, when the spray particles settle, a sufficient amount of the control component is uniformly diffused over the entire floor surface, so that a preferable control effect can be obtained. The uniform distribution of the control component to the entire floor surface means that the initial velocity of the spray particles sprayed from the pest and mite control aerosol is appropriate, and the spray particles immediately spread to every corner of the indoor space after spraying. It is thought to be because. When δ is less than 1.0, the amount of the control component attached to the floor surface may be insufficient. On the other hand, when δ exceeds 30, the diffusivity over the entire floor surface may be insufficient. Therefore, if δ is out of the range of 1.0 to 30, there is a possibility that a satisfactory control effect cannot be obtained.
　害虫、ダニ防除用エアゾールは、害虫、ダニ防除用エアゾールの全容量（ａ＋ｂ）に対するエアゾール原液の充填量ａの容量比率［ａ／（ａ＋ｂ）］が、以下の式（２）：
　　０．１　≦　［ａ／（ａ＋ｂ）］　≦　０．５　・・・　（２）
を満たすことが好ましい。容量比率が上記の範囲にあれば、十分な量の防除成分が床面全体へ均一に拡散する。容量比率が０．１より小さく噴射剤が多すぎると、防除成分の床面への付着量が不足する。一方、容量比率が０．５を超えると、噴霧粒子の沈降が速やか過ぎて床面全体への拡散性が不十分となる。 The pest and mite control aerosol has a volume ratio [a/(a+b)] of the filling amount a of the undiluted aerosol solution to the total volume (a+b) of the pest and mite control aerosol, which is represented by the following formula (2):
0.1 ≤ [a/(a+b)] ≤ 0.5 (2)
It is preferable to satisfy. When the volume ratio is within the above range, a sufficient amount of the controlling component is uniformly diffused over the entire floor surface. If the volume ratio is less than 0.1 and the amount of propellant is too large, the amount of the control component deposited on the floor surface will be insufficient. On the other hand, when the volume ratio exceeds 0.5, the spray particles settle down too quickly and the diffusivity over the entire floor becomes insufficient.
　本発明で用いる害虫、ダニ防除用エアゾールは少量噴射であるため、敢えて火気に対する危険性に留意する必要はないが、できる限り火気に対する危険性を低減させる観点から水性化処方を採用することもできる。この場合、エアゾール原液に含まれる水の量は２０～７０ｖ／ｖ％程度が適当であり、噴霧粒子の噴射パターンに影響を与えない範囲で、可溶化助剤として若干量の非イオン系界面活性剤を添加してもよい。非イオン系界面活性剤としては、例えば、ポリオキシエチレンアルキルエーテル類、ポリオキシエチレンアルキルフェニルエーテル類、ポリオキシエチレンポリオキシプロピレンアルキルエーテル類、ポリオキシエチレンアルキルアミノエーテル類などのエーテル類、ポリエチレングリコール脂肪酸エステル類、ポリオキシエチレンソルビタン脂肪酸エステル類、ポリオキシエチレングリセリン脂肪酸エステル類などの脂肪酸エステル類、ポリオキシエチレンスチレン化フェノール、脂肪酸のポリアルカロールアミドなどがあげられ、なかでも、エーテル類が適している。 The pests used in the present invention, the aerosol for controlling ticks is a small amount of injection, so it is not necessary to dare to pay attention to the risk of fire, but it is also possible to adopt an aqueous formulation from the viewpoint of reducing the risk of fire as much as possible. .. In this case, it is appropriate that the amount of water contained in the undiluted aerosol solution is about 20 to 70 v/v%, and a small amount of nonionic surfactant as a solubilizing agent is used as long as it does not affect the spray pattern of spray particles. Agents may be added. Examples of nonionic surfactants include ethers such as polyoxyethylene alkyl ethers, polyoxyethylene alkylphenyl ethers, polyoxyethylene polyoxypropylene alkyl ethers, polyoxyethylene alkylamino ethers, and polyethylene glycol. Fatty acid esters, polyoxyethylene sorbitan fatty acid esters, fatty acid esters such as polyoxyethylene glycerin fatty acid esters, polyoxyethylene styrenated phenols, polyalkalolamides of fatty acids, and the like, among which ethers are suitable ing.
　エアゾール原液には、上記成分に加え、カビ類、菌類等を対象とした防カビ剤、抗菌剤や殺菌剤、あるいは、芳香剤、消臭剤、安定化剤、帯電防止剤、消泡剤、賦形剤等を適宜配合することもできる。防カビ剤、抗菌剤や殺菌剤としては、ヒノキチオール、２－メルカプトベンゾチアゾール、２－（４－チアゾリル）ベンツイミダゾール、５－クロロ－２－メチル－４－イソチアゾリン－３－オン、トリホリン、３－メチル－４－イソプロピルフェノール、オルト－フェニルフェノール等を例示できる。また、芳香剤としては、オレンジ油、レモン油、ラベンダー油、ペパーミント油、ユーカリ油、シトロネラ油、ライム油、ユズ油、ジャスミン油、檜油、緑茶精油、リモネン、α－ピネン、リナロール、ゲラニオール、フェニルエチルアルコール、アミルシンナミックアルデヒド、クミンアルデヒド、ベンジルアセテート等の芳香成分、「緑の香り」と呼ばれる青葉アルコールや青葉アルデヒド配合の香料成分などがあげられるが、これらに限定されない。 In the aerosol stock solution, in addition to the above components, mildew, fungicides for fungi, antibacterial agents and bactericides, or fragrances, deodorants, stabilizers, antistatic agents, defoamers, Excipients and the like can also be appropriately mixed. As antifungal agents, antibacterial agents and bactericides, hinokitiol, 2-mercaptobenzothiazole, 2-(4-thiazolyl)benzimidazole, 5-chloro-2-methyl-4-isothiazolin-3-one, triphorin, 3- Examples include methyl-4-isopropylphenol and ortho-phenylphenol. As the fragrance, orange oil, lemon oil, lavender oil, peppermint oil, eucalyptus oil, citronella oil, lime oil, yuzu oil, jasmine oil, cypress oil, green tea essential oil, limonene, α-pinene, linalool, geraniol, Examples thereof include aromatic components such as phenylethyl alcohol, amyl cinnamic aldehyde, cumin aldehyde, and benzyl acetate, and perfume components including green leaf alcohol and green leaf aldehyde called “green scent”, but are not limited thereto.
　本発明で用いられる噴射剤としては、液化石油ガス（ＬＰＧ）、ジメチルエーテルやハイドロフルオロカーボン等の液化ガス、及び窒素ガス、炭酸ガス、亜酸化窒素、圧縮空気等の圧縮ガスがあげられ、そのうちの一種または二種以上を適宜採用することができる。噴射剤は噴霧粒子の床面や壁への付着率を考慮して、適宜決定すれば良いが、通常ＬＰＧを主体としたものが使いやすい。なお、噴射剤は、ゲージ圧（２０℃）を０．１～０．７ＭＰａに調整して使用することが好ましい。 Examples of the propellant used in the present invention include liquefied petroleum gas (LPG), liquefied gas such as dimethyl ether and hydrofluorocarbon, and compressed gas such as nitrogen gas, carbon dioxide gas, nitrous oxide, and compressed air. Alternatively, two or more kinds can be appropriately adopted. The propellant may be appropriately determined in consideration of the adhering rate of the spray particles to the floor surface or the wall, but it is usually easy to use one mainly composed of LPG. The propellant is preferably used after adjusting the gauge pressure (20° C.) to 0.1 to 0.7 MPa.
　上記害虫、ダニ防除用エアゾールは、一回当たりの噴射容量が１．０～５．０ｍＬである定量噴射バルブを備え、屋内で一定量噴射処理に供される。従来、定量噴射バルブの噴射容量は０．２～０．４ｍＬであったが、本発明で用いる定量噴射バルブにおいては容量の増量に伴い、必要な有効成分量がワンプッシュで噴射可能となった。その他、噴口、ノズル、容器等の形状については、その用途、使用目的等に応じて適宜選択することができる。例えば、上から押して噴射するボタンと斜め上方向きのノズルを備えた卓上タイプとしたり、小型容器の携帯用として設計することができる。 The aerosol for controlling pests and ticks is equipped with a fixed quantity injection valve with an injection volume of 1.0 to 5.0 mL each time, and is used for indoor fixed amount injection processing. Conventionally, the injection volume of a fixed-quantity injection valve was 0.2 to 0.4 mL, but in the fixed-quantity injection valve used in the present invention, the required effective component amount can be injected with one push as the volume increases. .. In addition, the shape of the nozzle, the nozzle, the container, and the like can be appropriately selected according to the application, the purpose of use, and the like. For example, it can be designed as a table-top type having a button that is pushed from above and ejecting and a nozzle that is directed obliquely upward, or can be designed as a portable small container.
　本発明の害虫、ダニ防除方法では、こうして得られた害虫、ダニ防除用エアゾールを用い、一回当たりの噴射容量を１．０～５．０ｍＬ、好ましくは１．０～３．０ｍＬとして、屋内空間で空中に向けて噴射処理を行うことにより、気中への防除成分の放出量が０．１～５０ｍｇ／ｍ３、好ましくは０．５～５０ｍｇ／ｍ３となるように設定されている。４．５～８畳の部屋に相当する容積が１８．８～３３．３ｍ３（面積７．５～１３．３ｍ２、高さ２．２～３．０ｍ）の屋内空間で噴射処理を行う場合、通常、エアゾール原液を１回噴射することにより、気中への防除成分の放出量が０．１～５０ｍｇ／ｍ３となるが、より容積の大きな屋内空間においては、その屋内空間の容積にあわせて気中の防除成分の放出量が０．１～５０ｍｇ／ｍ３となるようにエアゾール原液を複数回噴射することで、屋内空間の大きさに関わらず同様の防除効果を得ることができる。例えば、９～１６畳の部屋に相当する容積が３７．６～６６．６ｍ３（面積１５～２６．６ｍ２、高さ２．２～３．０ｍ）の屋内空間で噴射処理を行う場合、エアゾール原液を２回噴射することにより、気中への防除成分の放出量は０．１～５０ｍｇ／ｍ３となる。当該害虫、ダニ防除用エアゾールの使用頻度としては、基本的に１～２日に一度、防除成分の放出量が上記の範囲となるように施用すれば、匍匐害虫及び／又は屋内塵性ダニ類に対して数日間防除効果を維持できる。また、常温揮散性の防除成分を併用することによって、飛翔害虫に対する防除効果を付与することも可能である。 In the pest and mite control method of the present invention, the pest and mite control aerosol thus obtained is used, and the injection volume per injection is 1.0 to 5.0 mL, preferably 1.0 to 3.0 mL By performing the injection process toward the air in the space, the release amount of the control component to the air is set to 0.1 to 50 mg/m 3 , preferably 0.5 to 50 mg/m 3 . .. Injection processing is performed in an indoor space with a volume of 18.8 to 33.3 m 3 (area 7.5 to 13.3 m 2 , height 2.2 to 3.0 m) corresponding to a room of 4.5 to 8 tatami mats. In this case, normally, a single injection of an undiluted aerosol solution results in a release amount of the control ingredient of 0.1 to 50 mg/m 3 in the air, but in a larger indoor space, the volume of the indoor space is increased. In accordance with this, by spraying the aerosol stock solution multiple times so that the release amount of the control component in the air is 0.1 to 50 mg/m 3 , the same control effect can be obtained regardless of the size of the indoor space. it can. For example, when performing the injection process in an indoor space with a volume equivalent to a room of 9 to 16 tatami mats is 37.6 to 66.6 m 3 (area 15 to 26.6 m 2 , height 2.2 to 3.0 m), By spraying the aerosol undiluted solution twice, the release amount of the control component into the air becomes 0.1 to 50 mg/m 3 . As for the frequency of use of the pest and mite control aerosol, once a day or two once a day, if application is performed so that the release amount of the control component is within the above range, crawling pests and/or indoor dust mites The control effect can be maintained for several days. In addition, it is possible to impart a controlling effect against flying insects by using a controlling component which is volatile at room temperature.
　本発明の害虫、ダニ防除方法は、特に、チャバネゴキブリ、ワモンゴキブリ、クロゴキブリ等のゴキブリ類、アリ類、トコジラミ、ネッタイトコジラミ等のトコジラミ類、コクヌストモドキ、コクゾウムシ、シバンムシ、ダンゴムシ、ワラジムシなどの匍匐害虫、及びケナガコナダニ、コナヒョウヒダニ、ヤケヒョウヒダニ、ツメダニ等の屋内塵性ダニ類の防除に有効である。しかしながら、これらの匍匐害虫、ダニ類に限定されず、室内で飛翔して人に被害や不快感を与える害虫、例えば、アカイエカ、ヒトスジシマカ等の蚊類、ユスリカ類、イエバエ、チョウバエ、ブユ類、アブ類、ハチ類、ヨコバイ類などの各種害虫の防除にも十分適用されるものである。 The pests of the present invention, a method for controlling ticks, particularly, German cockroaches, American cockroaches, cockroaches such as black cockroaches, ants, bed bugs, bed bugs such as nettite white lice, beetle worms, weevil, beetle, dandelion, worm insects such as woodworm. , And is effective for controlling indoor dust mites such as A. niger, Dermatophagoides farinae, Dermatophagoides farinae, and Aedes mites. However, these crawling pests are not limited to mites, and pests that fly indoors and cause damage or discomfort to humans, for example, mosquitoes such as squid, Aedes albopictus, chironomids, house flies, butterfly flies, flies, and flies. It is also well applied to the control of various pests such as bees, bees and leafhoppers.
　具体的実施例ならびに試験例に基づいて、本発明の害虫、ダニ防除方法、及び害虫、ダニ防除用エアゾールを更に詳細に説明する。ただし、本発明はこれらに限定されるものではない。 Based on specific examples and test examples, the pest and mite control method of the present invention and the pest and mite control aerosol will be described in more detail. However, the present invention is not limited to these.
〔実施例１〕
　フェノトリン５３ｗ／ｖ％とメトフルトリン０．７ｗ／ｖ％とをエタノールに溶解してエアゾール原液を調製した。エアゾール原液の容量比率［ａ／（ａ＋ｂ）］が０．４となるように、このエアゾール原液（ａ）１２ｍＬと、噴射剤として液化石油ガス（ｂ）１８ｍＬとを、噴射容量が１．０ｍＬである定量噴霧バルブ付きエアゾール容器（耐圧容器）に加圧充填して、実施例１の害虫、ダニ防除用エアゾールを得た。このエアゾール原液の比重は０．９３であり、本エアゾールの噴射距離５ｃｍにおける噴射力は２６ｇｆであった。また、δは９．０であった。 [Example 1]
Phenothrin 53 w/v% and metfluthrin 0.7 w/v% were dissolved in ethanol to prepare an aerosol stock solution. 12 mL of this aerosol stock solution (a) and 18 mL of liquefied petroleum gas (b) as a propellant were injected at a volume of 1.0 mL so that the volume ratio [a/(a+b)] of the aerosol stock solution would be 0.4. An aerosol container (pressure resistant container) equipped with a certain metering spray valve was pressure-filled to obtain an aerosol for controlling pests and mites of Example 1. The specific gravity of this undiluted aerosol solution was 0.93, and the ejection force of the present aerosol at an ejection distance of 5 cm was 26 gf. Further, δ was 9.0.
　ほぼ密閉した容積２５ｍ３の部屋（６畳の部屋に相当　面積１０ｍ２）の中央で、害虫、ダニ防除用エアゾールをやや斜め上方に向けてワンショットすることにより噴射処理を行った。床面への防除成分の付着率（％）は、後述するガスクロマトグラフィーによる分析結果とエアゾールからの防除成分の放出量とから算出した。その結果、この噴射処理により噴射された全体の噴霧粒子のうちの７２％（すなわち、防除成分の放出量の７２％）が噴射処理から１時間後までに床面全体にわたり沈降・付着したことが確認された。そして、噴射処理から数日間、ゴキブリ類、アリ類やシバンムシ等の匍匐害虫に対して優れた防除効果を発揮するとともに、屋内塵性ダニ類を寄せ付けなかった。また、ほぼ密閉した容積５０ｍ３の部屋（１２畳の部屋に相当　面積２０ｍ２）の中央で、害虫、ダニ防除用エアゾールをやや斜め上方に向けて２回噴射することにより噴射処理を行ったところ、容積２５ｍ３の部屋の場合と同様に、匍匐害虫に対する防除効果を示すことも確認できた。 In the center of an almost closed room with a volume of 25 m 3 (equivalent to a room of 6 tatami mats with an area of 10 m 2 ), the spray treatment was carried out by one-shot one shot with an aerosol for controlling pests and mites. The adhesion rate (%) of the control component to the floor surface was calculated from the analysis result by gas chromatography described below and the amount of the control component released from the aerosol. As a result, 72% (that is, 72% of the released amount of the control component) of all the spray particles sprayed by this spraying process was settled and adhered over the entire floor surface by 1 hour after the spraying process. confirmed. Then, for several days after the spraying treatment, it exerted an excellent control effect against crawling pests such as cockroaches, ants, and hornworms, and did not attract indoor dust mites. In addition, in the center of an almost closed room with a volume of 50 m 3 (equivalent to an area of 12 tatami mats with an area of 20 m 2 ), the spray treatment was performed by spraying the pest and tick control aerosol twice slightly obliquely upward. It was also confirmed that, as in the case of a room with a volume of 25 m 3 , it exhibits a control effect against crawling pests.
〔実施例２～２４、比較例１～４〕
　実施例１に準じて表１に示す各種害虫、ダニ防除用エアゾールを調製した。なお、実施例２～２１、２３～２４、比較例１、３～４の害虫、ダニ防除用エアゾールには、噴射容量が１．０ｍＬである定量噴霧バルブ付きエアゾール容器を用い、実施例２２の害虫、ダニ防除用エアゾールには、噴射容量が２．２ｍＬである定量噴霧バルブ付きエアゾール容器を用い、比較例２の害虫、ダニ防除用エアゾールには、噴射容量が０．４ｍＬである定量噴霧バルブ付きエアゾール容器を用いた。 [Examples 2 to 24, Comparative Examples 1 to 4]
According to Example 1, aerosols for controlling various pests and mites shown in Table 1 were prepared. The aerosols for controlling pests and mites of Examples 2 to 21 and 23 to 24 and Comparative Examples 1 and 3 to 4 were aerosol containers with a metering spray valve having an injection volume of 1.0 mL. An aerosol container with a constant spray valve having a spray volume of 2.2 mL was used for the pest and mite control aerosol, and a fixed spray valve with a spray volume of 0.4 mL was used for the pest and mite control aerosol of Comparative Example 2. An attached aerosol container was used.
Figure JPOXMLDOC01-appb-T000001
Figure JPOXMLDOC01-appb-T000001
　実施例１～２４、比較例１～４の害虫、ダニ防除用エアゾールを用いて、下記に示す試験を行った。屋内塵性ダニ類に対しては、まず駆除効果を調べ、駆除効果が乏しい場合、忌避効果を評価した。試験結果を纏めて表２に示す。 Using the aerosols for controlling pests and mites of Examples 1 to 24 and Comparative Examples 1 to 4, the following tests were conducted. For indoor dust mites, first, the control effect was examined, and when the control effect was poor, the repellent effect was evaluated. The test results are summarized in Table 2.
（１）匍匐害虫に対する駆除効果
　２０×２０ｃｍのガラス板合計１２枚（チャバネゴキブリ用、ワモンゴキブリ用、及びクロヤマアリ用各４枚）を閉めきった容積２５ｍ３の部屋（面積１０ｍ２）の４隅に設置し、各ガラス板の上に直径約２０ｃｍのプラスチックリングを置き、各リング内に所定の供試昆虫（チャバネゴキブリ：♀成虫５匹、ワモンゴキブリ：幼虫５匹、クロヤマアリ：５匹）を放って自由に徘徊させた。供試エアゾールを部屋の中央でやや斜め上方に向けてワンショット（噴射容量：実施例１～２１、２３～２４、比較例１、３～４　１．０ｍＬ、実施例２２　２．２ｍＬ、比較例２　０．４ｍＬ）噴射した。２４時間放置して薬剤に暴露させた後、ガラス板を供試昆虫を含むリングごと別部屋に移し、餌を与え、更に２４時間後に供試昆虫の致死率を求めた。 (1) Extermination effect against crawling pests A total of 12 glass plates of 20 x 20 cm (4 for the German cockroach, 4 for the cockroach, and 4 for the black ant) are installed in the four corners of a room with a volume of 25 m 3 (area 10 m 2 ). Then, place a plastic ring with a diameter of about 20 cm on each glass plate, and freely release the predetermined test insects (German cockroach: 5 adults, 5 American cockroaches: 5 larvae, Black ant: 5) in each ring. I wandered around. One shot of the test aerosol was directed slightly obliquely upward in the center of the room (spray volume: Examples 1 to 21, 23 to 24, Comparative Examples 1 and 3 to 1.0 mL, Example 22 2.2 mL, Comparative Example 2 0.4 mL) was injected. After being left to stand for 24 hours to be exposed to the drug, the glass plate together with the ring containing the test insect was moved to another room and fed, and after 24 hours, the mortality rate of the test insect was determined.
（２）屋内塵性ダニ類に対する駆除効果
　直径９ｃｍ、高さ６ｃｍの腰高シャーレ８個（コナヒョウヒダニ用、及びケナガコナダニ用各４個）を閉めきった容積２５ｍ３の部屋（面積１０ｍ２）の４隅に設置し、腰高シャーレ内に所定の供試ダニ各約２００匹ずつ入れて供試した。供試エアゾールを部屋の中央でやや斜め上方に向けてワンショット噴射した。２４時間放置して薬剤に暴露させた後、供試ダニの致死率を求めた。 (2) Extermination effect against indoor dust mites Eight waist-high petri dishes with a diameter of 9 cm and a height of 6 cm (4 for Kona deer mite and 4 for Aedes albopictus) are fully enclosed in a room with a volume of 25 m 3 (area 10 m 2 ). Each of the predetermined test mites was placed in a high-backed petri dish and about 200 each of them was tested. A one-shot spray of the test aerosol was made in the center of the room and directed slightly obliquely upward. After being left for 24 hours to be exposed to the drug, the mortality rate of the test mites was determined.
（３）屋内塵性ダニ類に対する忌避効果
　上記「（２）屋内塵性ダニ類に対する駆除効果」試験において、供試ダニの替わりに直径約４ｃｍの綿布を部屋の４隅に設置し、供試エアゾールをワンショット噴射した。噴射から２４時間後にこの綿布を取り出して直径４ｃｍのシャーレにはめ込み、シャーレの中央部に誘引用培地５０ｍｇを置いた。これとは別に、直径９ｃｍのシャーレに供試コナヒョウヒダニ、又はケナガコナダニを培地とともに約１００００匹放ち、この直径９ｃｍのシャーレの中央部に、先に用意した直径４ｃｍのシャーレを置いた。同様に、供試エアゾールによる処理を行わなかった綿布を用いて無処理区を用意した。２４時間後に綿布上に侵入したダニ数を計数し、次式に従ってダニ忌避率を算出した。
　　ダニ忌避率（％）　＝　［（無処理区の侵入ダニ数－処理区の侵入ダニ数）　／　無処理区の侵入ダニ数］　×　１００ (3) Repellent effect against indoor dust mites In the above "(2) Control effect against indoor dust mites" test, a cotton cloth with a diameter of about 4 cm was placed in the four corners of the room instead of the tested mites. One-shot injection of aerosol. Twenty-four hours after the spraying, the cotton cloth was taken out and set in a petri dish having a diameter of 4 cm, and 50 mg of the citation medium was placed in the center of the petri dish. Separately from this, about 10000 samples of Dermatophagoides farinae or Dermatophagoides farinae were released together with a medium in a petri dish having a diameter of 9 cm, and the petri dish having a diameter of 4 cm prepared above was placed in the center of the petri dish having a diameter of 9 cm. Similarly, a non-treated section was prepared using a cotton cloth that was not treated with the test aerosol. After 24 hours, the number of mites that had invaded the cotton cloth was counted, and the tick repellent rate was calculated according to the following formula.
Mite repellent rate (%) = [(number of invading mites in untreated area-number of invading mites in treated area) / number of invading mites in untreated area] x 100
（４）防除成分の床面付着率
　閉めきった容積２５ｍ３の部屋（面積１０ｍ２）の床面の６～８ヵ所に２０×２０ｃｍのガラス板を部屋全体に均等に設置し、供試エアゾールを部屋の中央でやや斜め上方に向けてワンショット噴射した。噴射処理から１時間後に全てのガラス板を取り出し、付着した防除成分をアセトンで洗い出してガスクロマトグラフィーにより分析した。得られた分析値を基に、噴射処理から１時間後までに床面に沈降・付着した防除成分の、理論上の防除成分噴射全体量に対する比率（床面付着率）を求めた。また、ガラス板に付着した防除成分について、各ガラス板間のバラツキを解析し、噴霧粒子の拡散均一性を評価した。結果を、拡散均一性の良好なものから順に、Ａ、Ｂ、Ｃ、Ｄの４段階で示した。 (4) Adhesion rate of control components to the floor A 20 x 20 cm glass plate is evenly installed in the entire room at 6 to 8 locations on the floor of a room (area 10 m 2 ) with a closed volume of 25 m 3 and the test aerosol is used. Was fired in the center of the room a little diagonally upward and one shot. One hour after the spraying treatment, all the glass plates were taken out, the attached control component was washed out with acetone, and analyzed by gas chromatography. Based on the obtained analysis values, the ratio (floor surface adhesion rate) of the control component settled and adhered to the floor surface to the theoretical total amount of the control component injection within one hour after the injection treatment was determined. In addition, regarding the control component attached to the glass plate, the dispersion between the glass plates was analyzed to evaluate the diffusion uniformity of the spray particles. The results are shown in four stages of A, B, C, and D in order from the one with good diffusion uniformity.
Figure JPOXMLDOC01-appb-T000002
Figure JPOXMLDOC01-appb-T000002
　試験の結果、実施例１～２４の害虫、ダニ防除用エアゾールを用いた本発明の害虫、ダニ防除方法によれば、噴霧粒子が床面全体に略均一に拡散し、噴射から１時間後までに防除成分の６０％以上が床面に沈降・付着することが確認された。また、難揮散性の防除成分として、匍匐害虫防除用化合物を配合した実施例１～１６、２０～２４の害虫、ダニ防除用エアゾールを用いた場合には、匍匐害虫、及び屋内塵性ダニ類の何れに対しても、優れた防除効果を奏することが確認された。難揮散性の防除成分として、ダニ防除用化合物を配合した実施例１７～１９の害虫、ダニ防除用エアゾールを用いた場合には、屋内塵性ダニ類に対して優れた防除効果を奏することが確認された。 As a result of the test, according to the pests of Examples 1 to 24 and the pest and mite control method of the present invention using the aerosol for controlling ticks, the sprayed particles spread almost uniformly over the entire floor surface, and up to 1 hour after spraying. It was confirmed that 60% or more of the control components settle and adhere to the floor surface. Further, when the pests of Examples 1 to 16 and 20 to 24 containing the compound for controlling crawling pests and the aerosol for controlling ticks are used as the less volatile control component, the crawling pests and indoor dust mites are used. It was confirmed that an excellent control effect was exerted on any of the above. When the pests of Examples 17 to 19 and the aerosols for controlling ticks, which are mixed with a compound for controlling ticks, are used as the hardly volatile control component, an excellent controlling effect for indoor dust mites can be obtained. confirmed.
　これに対し、比較例１～４では、匍匐害虫、屋内塵性ダニ類の何れに対しても十分な防除効果が得られなかった。比較例１では、防除成分として、エムペントリンのような常温揮散性ピレスロイド化合物のみを配合したエアゾールを用いたために、床面付着率が小さくなり、その結果、防除効果が低くなったと考えられる。比較例２では、噴射容量が０．４ｍＬの定量噴射バルブを使用したために、ワンプッシュでは噴射される防除成分が必要量に達せず、その結果、防除効果が低くなったと考えられる。比較例３や比較例４のように、エアゾール原液の比重が本発明に規定する０．８５～１．１５の範囲から外れたものでは、噴霧粒子の拡散均一性が低かったことが、防除効果の低下の原因であると考えられる。 On the other hand, in Comparative Examples 1 to 4, a sufficient control effect was not obtained against both the crawling pests and indoor dust mites. In Comparative Example 1, since the aerosol containing only the room temperature volatile pyrethroid compound such as empentrin was used as the control component, the floor adhesion rate was reduced, and as a result, the control effect is considered to be low. In Comparative Example 2, since the fixed amount injection valve having an injection capacity of 0.4 mL was used, the control component to be injected did not reach the required amount with one push, and as a result, the control effect was considered to be low. When the specific gravity of the aerosol stock solution is out of the range of 0.85 to 1.15 specified in the present invention as in Comparative Example 3 and Comparative Example 4, the spray particles have low diffusion uniformity, which is a control effect. Is considered to be the cause of the decrease in
　本発明の害虫、ダニ防除方法、及び害虫、ダニ防除用エアゾールは、屋内だけでなく広範な害虫、ダニ防除を目的として利用することが可能である。 The pest and mite control method and the pest and mite control aerosol of the present invention can be used not only indoors but also for a wide range of pest and mite control.

Claims (9)

  1. 　防除成分及び有機溶剤を含有するエアゾール原液、並びに噴射剤を、一回当たりの噴射容量が１．０～５．０ｍＬである定量噴射バルブを備えたエアゾール容器に充填してなる害虫、ダニ防除用エアゾールを用いて噴射処理する害虫、ダニ防除方法であって、
    　前記防除成分は、３０℃における蒸気圧が１×１０－４ｍｍＨｇ未満である難揮散性化合物であり、
    　前記エアゾール原液の比重は、０．８５～１．１５であり、
    　前記害虫、ダニ防除用エアゾールの噴射力は、噴射距離５ｃｍにおいて１０～５０ｇｆであり、
    　前記噴射処理において屋内空間の気中に、前記防除成分の放出量が０．１～５０ｍｇ／ｍ３となるように前記エアゾール原液を噴射し、噴射から１時間後までに前記防除成分の６０％以上を前記屋内空間の床面全体に拡散させて付着させる害虫、ダニ防除方法。     For controlling pests and mites, an aerosol stock solution containing a control component and an organic solvent, and a propellant are filled in an aerosol container equipped with a metered injection valve having an injection volume of 1.0 to 5.0 mL per injection. A method for controlling pests and ticks, which is sprayed using an aerosol,
    The control component is a non-volatile compound having a vapor pressure at 30° C. of less than 1×10 −4 mmHg,
    The specific gravity of the aerosol stock solution is 0.85 to 1.15,
    The spray force of the pest and mite control aerosol is 10 to 50 gf at a spray distance of 5 cm,
    In the injection treatment, the aerosol stock solution is injected into the air of the indoor space so that the release amount of the control component is 0.1 to 50 mg/m 3, and 60% of the control component is injected one hour after the injection. A method for controlling pests and ticks, wherein the above is diffused and attached to the entire floor surface of the indoor space.
  2. 　前記害虫、ダニ防除用エアゾールは、前記エアゾール原液の充填量をａ、前記噴射剤の充填量をｂ、前記エアゾール原液の比重をＳ、前記害虫、ダニ防除用エアゾールの噴射力をＦとしたとき、以下の式（１）：
    　　δ　＝　［ａ／（ａ＋ｂ）］　×　Ｓ２　×　Ｆ　・・・　（１）
    で定義するδが１．０～３０の範囲にあるように構成されている請求項１に記載の害虫、ダニ防除方法。     When the pest and mite control aerosol is a filled amount of the aerosol stock solution, b is the propellant filled amount, S is the specific gravity of the aerosol stock solution, and F is the spray force of the pest and mite control aerosol. , The following equation (1):
    δ=[a/(a+b)]×S 2 ×F (1)
    2. The method for controlling pests and mites according to claim 1, wherein δ defined in 1. is in the range of 1.0 to 30.
  3. 　前記害虫、ダニ防除用エアゾールは、以下の式（２）：
    　　０．１　≦　［ａ／（ａ＋ｂ）］　≦　０．５　・・・　（２）
    を満たすように構成されている請求項２に記載の害虫、ダニ防除方法。     The pest and mite control aerosol has the following formula (2):
    0.1 ≤ [a/(a+b)] ≤ 0.5 (2)
    The method for controlling pests and mites according to claim 2, which is configured to satisfy the following.
  4. 　前記害虫、ダニ防除用エアゾールは、以下の式（３）：
    　　３．０　≦　δ　≦　１５　・・・　（３）
    を満たすように構成されている請求項２又は３に記載の害虫、ダニ防除方法。     The pest and mite control aerosol has the following formula (3):
    3.0 ≤ δ ≤ 15 (3)
    The method for controlling pests and mites according to claim 2 or 3, which is configured to satisfy the following.
  5. 　前記難揮散性化合物は、フェノトリン、シフェノトリン、ペルメトリン、シペルメトリン、シフルトリン、ビフェントリン、フェンプロパトリン、トラロメトリン、エトフェンプロックス、及びジノテフランからなる群から選択される少なくとも１種の匍匐害虫防除用化合物である請求項１～４の何れか一項に記載の害虫、ダニ防除方法。 The fugitive compound is a compound for controlling ecstasy pests of at least one species selected from the group consisting of phenothrin, cyphenothrin, permethrin, cypermethrin, cyfluthrin, bifenthrin, phenpropatrine, tralomethrin, etofenprox, and dinotefuran. A method for controlling pests and mites according to any one of claims 1 to 4.
  6. 　前記難揮散性化合物は、アミドフルメト、安息香酸ベンジル、サリチル酸フェニル、サリチル酸ベンジル、セバシン酸ジブチル、セバシン酸ジプロピル、アジピン酸ジブチル、フタル酸ジエチル、フタル酸ジブチル、及びｐ－メンタン－３，８－ジオールからなる群から選択される少なくとも１種のダニ防除用化合物である請求項１～４の何れか一項に記載の害虫、ダニ防除方法。 The fugitive compound includes amidoflumet, benzyl benzoate, phenyl salicylate, benzyl salicylate, dibutyl sebacate, dipropyl sebacate, dibutyl adipate, diethyl phthalate, dibutyl phthalate, and p-menthane-3,8-diol. The method for controlling pests and mites according to any one of claims 1 to 4, which is at least one tick controlling compound selected from the group consisting of:
  7. 　前記有機溶剤は、炭素数が２～３の低級アルコールである請求項１～６の何れか一項に記載の害虫、ダニ防除方法。 The method for controlling pests and mites according to any one of claims 1 to 6, wherein the organic solvent is a lower alcohol having 2 to 3 carbon atoms.
  8. 　前記屋内空間の床面の面積は、７．５～２６．６ｍ２である請求項１～７の何れか一項に記載の害虫、ダニ防除方法。 The method for controlling pests and mites according to any one of claims 1 to 7, wherein an area of a floor surface of the indoor space is 7.5 to 26.6 m 2 .
  9. 　防除成分及び有機溶剤を含有するエアゾール原液、並びに噴射剤を、一回当たりの噴射容量が１．０～５．０ｍＬである定量噴射バルブを備えたエアゾール容器に充填してなる害虫、ダニ防除用エアゾールであって、
    　前記防除成分は、３０℃における蒸気圧が１×１０－４ｍｍＨｇ未満である難揮散性化合物であり、
    　前記エアゾール原液の比重は、０．８５～１．１５であり、
    　前記害虫、ダニ防除用エアゾールの噴射力は、噴射距離５ｃｍにおいて１０～５０ｇｆであり、
    　前記定量噴射バルブを介した一回の噴射処理により屋内空間の気中に、前記防除成分の放出量が０．１～５０ｍｇ／ｍ３となるように前記エアゾール原液を噴射した場合、噴射から１時間後までに前記防除成分の６０％以上が、前記屋内空間の床面全体に拡散して付着する害虫、ダニ防除用エアゾール。     For controlling pests and mites, an aerosol stock solution containing a control component and an organic solvent, and a propellant are filled in an aerosol container equipped with a metered injection valve having an injection volume of 1.0 to 5.0 mL per injection. An aerosol,
    The control component is a non-volatile compound having a vapor pressure at 30° C. of less than 1×10 −4 mmHg,
    The specific gravity of the aerosol stock solution is 0.85 to 1.15,
    The spray force of the pest and mite control aerosol is 10 to 50 gf at a spray distance of 5 cm,
    When the aerosol stock solution is injected into the air of the indoor space by a single injection process through the fixed-quantity injection valve so that the release amount of the control component is 0.1 to 50 mg/m 3 , An aerosol for controlling pests and mites, in which 60% or more of the control component diffuses and adheres to the entire floor surface of the indoor space by the time.
PCT/JP2019/047561 2018-12-14 2019-12-05 Pest/mite control method and pest/mite control aerosol WO2020121931A1 (en)

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