WO2019226744A1 - Power supplies and methods of using miniaturized intra-body controllable medical device - Google Patents

Power supplies and methods of using miniaturized intra-body controllable medical device Download PDF

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Publication number
WO2019226744A1
WO2019226744A1 PCT/US2019/033475 US2019033475W WO2019226744A1 WO 2019226744 A1 WO2019226744 A1 WO 2019226744A1 US 2019033475 W US2019033475 W US 2019033475W WO 2019226744 A1 WO2019226744 A1 WO 2019226744A1
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WIPO (PCT)
Prior art keywords
medical device
power supply
intra
host structure
interior area
Prior art date
Application number
PCT/US2019/033475
Other languages
French (fr)
Inventor
Christopher J.P. Velis
Matthew P. Palmer
Original Assignee
Velis Christopher J P
Palmer Matthew P
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Application filed by Velis Christopher J P, Palmer Matthew P filed Critical Velis Christopher J P
Publication of WO2019226744A1 publication Critical patent/WO2019226744A1/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A61B1/041Capsule endoscopes for imaging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00002Operational features of endoscopes
    • A61B1/00025Operational features of endoscopes characterised by power management
    • A61B1/00027Operational features of endoscopes characterised by power management characterised by power supply
    • A61B1/00032Operational features of endoscopes characterised by power management characterised by power supply internally powered

Definitions

  • the present invention relates generally to power supplies for miniaturized intra-body controllable medical devices.
  • the power supply includes miniaturized batteries, fuel cells, electrochemical reactors, piezoelectric devices, energy harvesting devices that obtains thermal and/or chemical reaction energy from the fluids in the tissue of the lumen and adjacent organs, thermal reactors, heat absorption energy conversion devices and triboelectric energy harvesting devices.
  • the power supply may be used to power a propulsion system, a deployment system, a control system, an intra-device storage system, an imaging system, a therapy system, a sample and data gathering system, and/or a material dispensing system all of which may be components of the intra-body controllable medical device.
  • the invention includes materials and methods for using an intrabody controllable medical device.
  • Natural orifices include the nostrils, mouth, ear canals, nasolacrimal ducts, anus, urinary meatus, vagina, and nipples.
  • the lumens include the interior of the gastrointestinal tract, the pathways of the bronchi in the lungs, the interior of the renal tubules and urinary collecting ducts, the pathways of the vagina, uterus, and fallopian tubes. From within these orifices and lumens, physicians can create an incision to gain access to almost any region of the body.
  • Laparoscopic procedures allow the physician to use a small“key-hole” surgical opening and specially designed instruments to gain access to regions within the body. Initially, laparoscopic instruments were linear in nature, and required a straight obstruction free“line-of-sight” to access regions of the body. Endoscopic procedures allow the physician to access regions of the digestive system by passing flexible instruments through either the mouth or rectum. [0004] Recently, physicians have begun to control these instruments using robots. These robots are typically connected in master/slave configuration, where the robot translates the physician’s movements into instrument movements. Robotic controls have also allowed for advent of flexible laparoscopic instruments. Medical robots still require a physician to be actively controlling the movements and actions of the devices being controlled and require large expensive capital equipment and dedicated operating room spaces.
  • pill capsules have been invented that allow for a patient to ingest the capsule and as it passes through the digestive system takes pictures. There are no means for: controlling the motion of these devices, tracking or controlling the orientation, speed or location of these devices, accurately knowing where pictures were taken, and performing any type of surgical procedure or delivering therapy.
  • a powered medical device for intra-body conveyance includes a host structure defining an interior area and one or more power supplies.
  • the power supplies include a miniaturized battery, a fuel cell, an electrochemical reactor, a piezoelectric device, an energy harvesting device that obtains thermal and/or chemical reaction energy from the fluids in and tissue of the lumen and adjacent organs, a thermal reactor, a heat absorption energy conversion device and/or a triboelectric energy harvesting device.
  • the power supply is charged through induction charging.
  • the medical device further includes an induction energy receiver located within the host structure and an induction energy transmitter located outside a patient’s body.
  • the power supply is charged through ultrasonic charging.
  • the host structure includes a clinically inert material, a sterilizable material, an elastomeric material, a chemically reactive material, a chemically inert material, a disintegrable material, a dissolvable material, and a collapsible material and/or a material having physical and chemical properties to withstand exposure to bodily fluids for a predetermined period of time.
  • the host structure has a diameter of about 25mm and a length of about 75mm.
  • a method of using the device as described above includes at least one of use in a gastro/intestinal tract, use in urology applications, use in a lung, use in a bladder, use in a nasal system, use in a reproductive system, use in performing
  • TURBT Transurethral Resection of Bladder Tumors
  • TURP Transurethral Resection of the Prostate
  • trans rectal prostate ultrasound, biopsy, and radiation treatment use in trans rectal prostate ultrasound, biopsy, and radiation treatment.
  • a method of providing therapy to a patient includes the use of a medical device for intra-body conveyance.
  • the medical device includes a host structure defining an interior area and at least one power supply.
  • the power supply is charged through induction charging.
  • the host structure includes a clinically inert material, a sterilizable material, an elastomeric material, a chemically reactive material, a chemically inert material, a disintegrable material, a dissolvable material, and a collapsible material and/or a material having physical and chemical properties to withstand exposure to bodily fluids for a predetermined period of time.
  • the power supply is charged through ultrasonic charging.
  • a system in another aspect of the invention, includes first medical device, a second medical device, and a tether.
  • the first medical device has a first host structure defining a first interior area, and a first power supply.
  • the second medical device has a second host structure defining a second interior area, and a second power supply.
  • the tether can connect the first power supply to the second power supply, thereby allowing the transfer of power from the first power supply to the second power supply.
  • the first and second host structures each have a diameter of about 25mm and a length of about 75mm.
  • the first medical device is located inside a patient’s body and the second medical device is located outside the patient’s body.
  • FIG. 1 illustrates a representative intra-body controllable medical device formed in accordance with the present invention
  • FIG. 2 illustrates an alternative representation of an intra-body controllable medical device formed in accordance with the present invention
  • FIGS. 3A and 3B illustrate power supply systems for powering an intra-body controllable medical device
  • FIG. 4 illustrates the use of induction charging to power an intra-body controllable medical device
  • FIG. 5 illustrates a configuration for tethered power transfer between two intra-body controllable medical devices.
  • FIG. 1 illustrates an exemplary intra-body controllable medical device (hereinafter “the medical devices”).
  • the intra-body controllable medical device 5 is capsule shaped.
  • Intra-body controllable medical device 5 has a distal end 10, a proximal end 15, and body 20 connecting the distal end 10 and proximal end 15.
  • a control unit, a power supply system, an intra-device storage system, an imaging system, a therapy system, a sample and data gathering system, and a material dispensing system is located within body 20 of the medical device 5, as described herein.
  • the intra-body controllable medical device is sized according to the anatomy that it will need to navigate, and the method used to deliver it.
  • overall dimensions for an intra-body controllable device operating within the gastrointestinal track may have a diameter D of about 25mm and a length L of about 75mm. More preferably, the device may have a diameter D of about 15 mm and a length L of about 50mm. Most preferably, the diameter D is less than about l5mm and a length L of less than about 50mm.
  • Overall dimensions for an intra-body controllable device that is delivered using a scope may have a diameter D of about 20mm in diameter D and a length L of about 75mm. More preferably, the diameter D is about l5mm and the length L is about 50mm. Most preferably, the diameter D is less than l5mm and the length L is less than 50mm. Control system, power supply system, intra- device storage system, imaging system, therapy system, sample and data gathering system, and material dispensing systems are sized to fit within these dimensional guidelines.
  • the intra-body controllable medical device 5 is octopus shaped.
  • the intra-body controllable medical device 5 has a main body 30, and appendages 35.
  • Appendages 35 are used for propulsion, covering or wrapping the host structure 20, forming a portion of the host structure 20 or to perform a therapeutic or diagnostic task.
  • a control unit, power supply systems, an intra-device storage system, an imaging system, a therapy system, a sample and data gathering system, and a material dispensing system may be located within main body 30 and/or appendages 35 of the device or in the interior areas 22 of the host structure 20.
  • the present invention is generally directed to power supply systems 175 for an intra-body medical device 5 and more particularly to power supplies and storage devices that provide power for propulsion, control and operation of subcomponents within and around the intra-body controllable medical device and ancillary devices connectable to the intra-body controllable medical device.
  • the miniaturized power supplies include batteries, fuel cells, electrochemical reactors, piezoelectric devices, energy harvesting devices that obtain thermal and/or chemical reaction energy from the fluids in the tissue of the lumen and adjacent organs, thermal reactors heat absorption energy conversion devices and triboelectric energy harvesting devices.
  • Batteries may include any of the kind known in the art including, but not limited to, alkaline batteries, atomic batteries, lead-acid batteries, lithium ion batteries, magnesium-ion batteries, nickel-cadmium batteries, nickel metal hydride batteries and rechargeable alkaline batteries.
  • Electrochemical reactors may store the chemical required to create electricity within the device. Alternatively, electrochemical reactors may use fluids found within the body to react with chemicals stored within or on the device to create electricity.
  • Piezeoelectric devices may create electricity by harvesting either the body’s own motion (e.g. peristalsis) or the motion of the device as it moves within the lumen. Heat absorption devices may harvest energy from the body’s temperature to create electricity.
  • Triboelectric energy harvesting devices generate electricity as the body of the device comes into frictional contact with the lumen of the body it is passing within. Additionally, energy may be stored by the device using capacitors, thermal medium, batteries and mechanical expansion devices (e.g., springs and balloons).
  • the intra-body controllable medical device 5 can be directly powered by induction energy transfer from the outside of the body 190 or inside of the body 190.
  • An induction energy receiver 180 can be located within device 5.
  • An induction energy transmitter 185 can be located outside body 190.
  • the device may function on another internal energy storage device and be recharged by induction, charging when sufficient stored electricity has been consumed.
  • Other forms of energy transport are also contemplated and include ultrasonic power transmission.
  • one intra-body controllable medical device 5 can be tethered to a second intra-body controllable medical device 5.
  • Tether 195 can transfer electricity from power source 175 in a first device to a second power source 175 of the second device.
  • the second intra-body controllable medical device 5 may be located outside the body 190.
  • the two devices may be permanently tethered together, or they may tether when the transfer of electricity is required.
  • the present invention includes materials for manufacture of an intrabody controllable medical devices, and in particular to materials for such devices that are clinically inert, sterilizable, elastomeric (e.g., contractible and expandable), chemically reactive, chemically inert, dissolvable, collapsible and have physical and chemical properties to withstand exposure to bodily fluids for precise predetermined periods of time.
  • materials include polymers, metallic alloys, shape memory polymers, shape memory metal alloys, shape memory ceramics, composites, silicones, thermoplastic polyurethane-based materials, excipients, zeolite adsorbents and styrene-butadiene rubbers (SBR).
  • Materials may further include biodegradable materials such as paper, starches, biodegradable material such as gelatin or collagen.
  • the intra-body controllable medical devices may be disposable, disintegrable and selectively collapsible intra-body controllable medical devices and materials and structures thereof.
  • the intra-body controllable medical devices are manufactured of a material such as an elastomer (e.g., nitrile) that can expand and contract, for example, by inflating and deflating them.
  • the intra-body controllable medical devices are manufactured from a biodegradable, disintegrable or dissolvable material, including paper, starches, biodegradable material such as gelatin or collagen and/or synthetic natural polymers.
  • the collapsible intra-body controllable medical devices are configured to be flattened, extruded, stretched or disassembled in the lumen.
  • the intra-body controllable medical devices are disposed of in the lumen or via discharge therefrom without the need to recover the intra-body controllable medical devices for analysis, inspection or future use.
  • the present invention is directed to methods for using intra-body controllable medical devices in the medical field and in particular for use in administering medications and therapy, deploying medical devices, imaging, and surgery.
  • the methods for using intra-body controllable medical devices includes applications in the gastro/intestinal tract (e.g. colonoscopy), urology applications, in the lungs, bladder, nasal and reproductive systems, in performing Transurethral Resection of Bladder Tumors (TURBT), Transurethral Resection of the Prostate (TURP) and transrectal prostate ultrasound, biopsy, and radiation treatment.
  • the methods for using intrabody controllable medical devices include use in procedural environments, operatory/surgical procedures, ambulatory/out-patient procedures and non-procedural environments such as home use.

Abstract

A medical device for intra-body conveyance includes a host structure defining an interior area and at least one power supply. The power supplies can include miniaturized batteries, fuel cells, electrochemical reactors, piezoelectric devices, energy harvesting devices that obtains thermal and/or chemical reaction energy from the fluids in and tissue of the lumen and adjacent organs, thermal reactors, heat absorption energy conversion devices and triboelectric energy harvesting devices.

Description

POWER SUPPLIES AND METHODS OF USING MINIATURIZED INTRA-BODY
CONTROLLABLE MEDICAL DEVICE
FIELD OF THE INVENTION
[0001] The present invention relates generally to power supplies for miniaturized intra-body controllable medical devices. The power supply includes miniaturized batteries, fuel cells, electrochemical reactors, piezoelectric devices, energy harvesting devices that obtains thermal and/or chemical reaction energy from the fluids in the tissue of the lumen and adjacent organs, thermal reactors, heat absorption energy conversion devices and triboelectric energy harvesting devices. The power supply may be used to power a propulsion system, a deployment system, a control system, an intra-device storage system, an imaging system, a therapy system, a sample and data gathering system, and/or a material dispensing system all of which may be components of the intra-body controllable medical device. Further, the invention includes materials and methods for using an intrabody controllable medical device.
BACKGROUND OF THE INVENTION
[0002] Many medical procedures require the physician to gain access to regions within the body in order to complete a diagnosis or provide therapy to a patient. Often, physicians access internal regions of the body through the body’s own natural orifices and lumens. Natural orifices include the nostrils, mouth, ear canals, nasolacrimal ducts, anus, urinary meatus, vagina, and nipples. The lumens include the interior of the gastrointestinal tract, the pathways of the bronchi in the lungs, the interior of the renal tubules and urinary collecting ducts, the pathways of the vagina, uterus, and fallopian tubes. From within these orifices and lumens, physicians can create an incision to gain access to almost any region of the body.
[0003] Traditional methods for gaining access to regions within the body include open surgical procedures, laparoscopic procedures and endoscopic procedures. Laparoscopic procedures allow the physician to use a small“key-hole” surgical opening and specially designed instruments to gain access to regions within the body. Initially, laparoscopic instruments were linear in nature, and required a straight obstruction free“line-of-sight” to access regions of the body. Endoscopic procedures allow the physician to access regions of the digestive system by passing flexible instruments through either the mouth or rectum. [0004] Recently, physicians have begun to control these instruments using robots. These robots are typically connected in master/slave configuration, where the robot translates the physician’s movements into instrument movements. Robotic controls have also allowed for advent of flexible laparoscopic instruments. Medical robots still require a physician to be actively controlling the movements and actions of the devices being controlled and require large expensive capital equipment and dedicated operating room spaces.
[0005] Additionally, pill capsules have been invented that allow for a patient to ingest the capsule and as it passes through the digestive system takes pictures. There are no means for: controlling the motion of these devices, tracking or controlling the orientation, speed or location of these devices, accurately knowing where pictures were taken, and performing any type of surgical procedure or delivering therapy.
[0006] Thus, improvements are desirable in this field of technology. It would be beneficial to combine the ability to perform surgical procedures and provide therapy using robotic instruments with the footprint, size, and maneuverability of capsule systems or other structures. It would be beneficial to provide a means for controlling the movement of a medical device so that the surgeon can navigate it to a specific location. In order to accomplish these tasks, novel power supplies are required to power these devices for a sufficient time while being a useful size for the intended application.
SUMMARY
[0007] There is disclosed herein a powered medical device for intra-body conveyance. A medical device for intra-body conveyance includes a host structure defining an interior area and one or more power supplies.
[0008] In some embodiments, the power supplies include a miniaturized battery, a fuel cell, an electrochemical reactor, a piezoelectric device, an energy harvesting device that obtains thermal and/or chemical reaction energy from the fluids in and tissue of the lumen and adjacent organs, a thermal reactor, a heat absorption energy conversion device and/or a triboelectric energy harvesting device.
[0009] In one embodiment, the power supply is charged through induction charging.
[00010] In certain embodiments, the medical device further includes an induction energy receiver located within the host structure and an induction energy transmitter located outside a patient’s body. [00011] In a particular embodiment, the power supply is charged through ultrasonic charging.
[00012] In some embodiments, the host structure includes a clinically inert material, a sterilizable material, an elastomeric material, a chemically reactive material, a chemically inert material, a disintegrable material, a dissolvable material, and a collapsible material and/or a material having physical and chemical properties to withstand exposure to bodily fluids for a predetermined period of time.
[00013] In certain embodiments, the host structure has a diameter of about 25mm and a length of about 75mm.
[00014] In one aspect of the invention a method of using the device as described above includes at least one of use in a gastro/intestinal tract, use in urology applications, use in a lung, use in a bladder, use in a nasal system, use in a reproductive system, use in performing
Transurethral Resection of Bladder Tumors (TURBT), use in Transurethral Resection of the Prostate (TURP), use in trans rectal prostate ultrasound, biopsy, and radiation treatment.
[00015] In another aspect of the invention, a method of providing therapy to a patient includes the use of a medical device for intra-body conveyance. The medical device includes a host structure defining an interior area and at least one power supply.
[00016] In one embodiment of this aspect, the power supply is charged through induction charging.
[00017] In some embodiments, the host structure includes a clinically inert material, a sterilizable material, an elastomeric material, a chemically reactive material, a chemically inert material, a disintegrable material, a dissolvable material, and a collapsible material and/or a material having physical and chemical properties to withstand exposure to bodily fluids for a predetermined period of time.
[00018] In one embodiment, the power supply is charged through ultrasonic charging.
[00019] In another aspect of the invention, a system includes first medical device, a second medical device, and a tether. The first medical device has a first host structure defining a first interior area, and a first power supply. The second medical device has a second host structure defining a second interior area, and a second power supply. The tether can connect the first power supply to the second power supply, thereby allowing the transfer of power from the first power supply to the second power supply.
[00020] In one embodiment of this aspect, the first and second host structures each have a diameter of about 25mm and a length of about 75mm. [00021] In a particular embodiment, the first medical device is located inside a patient’s body and the second medical device is located outside the patient’s body.
DESCRIPTION OF THE DRAWINGS
[00022] The drawings show embodiments of the disclosed subject matter for the purpose of illustrating the invention. However, it should be understood that the present application is not limited to the precise arrangements and instrumentalities shown in the drawings, wherein:
[00023] FIG. 1 illustrates a representative intra-body controllable medical device formed in accordance with the present invention;
[00024] FIG. 2 illustrates an alternative representation of an intra-body controllable medical device formed in accordance with the present invention;
[00025] FIGS. 3A and 3B illustrate power supply systems for powering an intra-body controllable medical device;
[00026] FIG. 4 illustrates the use of induction charging to power an intra-body controllable medical device; and
[00027] FIG. 5 illustrates a configuration for tethered power transfer between two intra-body controllable medical devices.
PET ATT ED DESCRIPTION OF THE PREFERRED EMBODIMENT
[00028] FIG. 1 illustrates an exemplary intra-body controllable medical device (hereinafter “the medical devices”). In one embodiment, the intra-body controllable medical device 5 is capsule shaped. Intra-body controllable medical device 5 has a distal end 10, a proximal end 15, and body 20 connecting the distal end 10 and proximal end 15. A control unit, a power supply system, an intra-device storage system, an imaging system, a therapy system, a sample and data gathering system, and a material dispensing system is located within body 20 of the medical device 5, as described herein. The intra-body controllable medical device is sized according to the anatomy that it will need to navigate, and the method used to deliver it. For example, overall dimensions for an intra-body controllable device operating within the gastrointestinal track may have a diameter D of about 25mm and a length L of about 75mm. More preferably, the device may have a diameter D of about 15 mm and a length L of about 50mm. Most preferably, the diameter D is less than about l5mm and a length L of less than about 50mm. Overall dimensions for an intra-body controllable device that is delivered using a scope may have a diameter D of about 20mm in diameter D and a length L of about 75mm. More preferably, the diameter D is about l5mm and the length L is about 50mm. Most preferably, the diameter D is less than l5mm and the length L is less than 50mm. Control system, power supply system, intra- device storage system, imaging system, therapy system, sample and data gathering system, and material dispensing systems are sized to fit within these dimensional guidelines.
[00029] As shown in the exemplary embodiment of FIG. 2, the intra-body controllable medical device 5 is octopus shaped. The intra-body controllable medical device 5 has a main body 30, and appendages 35. Appendages 35 are used for propulsion, covering or wrapping the host structure 20, forming a portion of the host structure 20 or to perform a therapeutic or diagnostic task. A control unit, power supply systems, an intra-device storage system, an imaging system, a therapy system, a sample and data gathering system, and a material dispensing system may be located within main body 30 and/or appendages 35 of the device or in the interior areas 22 of the host structure 20.
[00030] As shown in FIG. 3 A and FIG. 3B, the present invention is generally directed to power supply systems 175 for an intra-body medical device 5 and more particularly to power supplies and storage devices that provide power for propulsion, control and operation of subcomponents within and around the intra-body controllable medical device and ancillary devices connectable to the intra-body controllable medical device. In particular, the miniaturized power supplies include batteries, fuel cells, electrochemical reactors, piezoelectric devices, energy harvesting devices that obtain thermal and/or chemical reaction energy from the fluids in the tissue of the lumen and adjacent organs, thermal reactors heat absorption energy conversion devices and triboelectric energy harvesting devices. Batteries may include any of the kind known in the art including, but not limited to, alkaline batteries, atomic batteries, lead-acid batteries, lithium ion batteries, magnesium-ion batteries, nickel-cadmium batteries, nickel metal hydride batteries and rechargeable alkaline batteries. Electrochemical reactors may store the chemical required to create electricity within the device. Alternatively, electrochemical reactors may use fluids found within the body to react with chemicals stored within or on the device to create electricity. Piezeoelectric devices may create electricity by harvesting either the body’s own motion (e.g. peristalsis) or the motion of the device as it moves within the lumen. Heat absorption devices may harvest energy from the body’s temperature to create electricity.
Triboelectric energy harvesting devices generate electricity as the body of the device comes into frictional contact with the lumen of the body it is passing within. Additionally, energy may be stored by the device using capacitors, thermal medium, batteries and mechanical expansion devices (e.g., springs and balloons).
[00031] Additionally, as seen in FIG. 4, the intra-body controllable medical device 5 can be directly powered by induction energy transfer from the outside of the body 190 or inside of the body 190. An induction energy receiver 180 can be located within device 5. An induction energy transmitter 185 can be located outside body 190. Alternatively, the device may function on another internal energy storage device and be recharged by induction, charging when sufficient stored electricity has been consumed. Other forms of energy transport are also contemplated and include ultrasonic power transmission.
[00032] Alternatively, as seen in FIG. 5, one intra-body controllable medical device 5 can be tethered to a second intra-body controllable medical device 5. Tether 195 can transfer electricity from power source 175 in a first device to a second power source 175 of the second device. The second intra-body controllable medical device 5 may be located outside the body 190. The two devices may be permanently tethered together, or they may tether when the transfer of electricity is required.
[00033] The present invention includes materials for manufacture of an intrabody controllable medical devices, and in particular to materials for such devices that are clinically inert, sterilizable, elastomeric (e.g., contractible and expandable), chemically reactive, chemically inert, dissolvable, collapsible and have physical and chemical properties to withstand exposure to bodily fluids for precise predetermined periods of time. Such materials include polymers, metallic alloys, shape memory polymers, shape memory metal alloys, shape memory ceramics, composites, silicones, thermoplastic polyurethane-based materials, excipients, zeolite adsorbents and styrene-butadiene rubbers (SBR). Materials may further include biodegradable materials such as paper, starches, biodegradable material such as gelatin or collagen.
[00034] The intra-body controllable medical devices may be disposable, disintegrable and selectively collapsible intra-body controllable medical devices and materials and structures thereof. The intra-body controllable medical devices are manufactured of a material such as an elastomer (e.g., nitrile) that can expand and contract, for example, by inflating and deflating them. The intra-body controllable medical devices are manufactured from a biodegradable, disintegrable or dissolvable material, including paper, starches, biodegradable material such as gelatin or collagen and/or synthetic natural polymers. The collapsible intra-body controllable medical devices are configured to be flattened, extruded, stretched or disassembled in the lumen. Thus, the intra-body controllable medical devices are disposed of in the lumen or via discharge therefrom without the need to recover the intra-body controllable medical devices for analysis, inspection or future use.
[00035] The present invention is directed to methods for using intra-body controllable medical devices in the medical field and in particular for use in administering medications and therapy, deploying medical devices, imaging, and surgery. The methods for using intra-body controllable medical devices includes applications in the gastro/intestinal tract (e.g. colonoscopy), urology applications, in the lungs, bladder, nasal and reproductive systems, in performing Transurethral Resection of Bladder Tumors (TURBT), Transurethral Resection of the Prostate (TURP) and transrectal prostate ultrasound, biopsy, and radiation treatment. The methods for using intrabody controllable medical devices include use in procedural environments, operatory/surgical procedures, ambulatory/out-patient procedures and non-procedural environments such as home use.
[00036] Although the present invention has been disclosed and described with reference to certain embodiments thereof, it should be noted that other variations and modifications may be made, and it is intended that the following claims cover the variations and modifications within the true scope of the invention.

Claims

What is claimed is:
1. A medical device for intra-body conveyance, the medical device comprising: a host structure defining an interior area; and at least one power supply in communication therewith.
2. The medical device of claim 1, wherein the at least one power supply includes at least one of a miniaturized battery, a fuel cell, an electrochemical reactor, a piezoelectric device, an energy harvesting device that obtains thermal and/or chemical reaction energy from the fluids in and tissue of the lumen and adjacent organs, a thermal reactor, a heat absorption energy conversion device and a triboelectric energy harvesting device.
3. The medical device of claim 1, wherein the at least one power supply is charged through induction charging.
4. The medical device of claim 3, further including an induction energy receiver located within the host structure and an induction energy transmitter located outside a patient’s body.
5. The medical device of claim 1 wherein the at least one power supply is charged through ultrasonic charging.
6. The medical device of claim 1, wherein the host structure includes at least one of a clinically inert material, a sterilizable material, an elastomeric material, a chemically reactive material, a chemically inert material, a disintegrable material, a dissolvable material, and a collapsible material and a material having physical and chemical properties to withstand exposure to bodily fluids for a predetermined period of time.
7. The medical device of claim 1, wherein the host structure has a diameter of about 25mm and a length of about 75mm.
8. The medical device of claim 1, wherein the at least one power supply is disposed in the interior area.
9 The medical device of claim 1, wherein the at least one power supply is located outside the interior area.
10. A method for using the medical device of any one of the preceding claims, the method being directed to at least one of use in a gastro/intestinal tract, use in urology
applications, use in a lung, use in a bladder, use in a nasal system, use in a reproductive system, use in performing Transurethral Resection of Bladder Tumors (TURBT), use in Transurethral Resection of the Prostate (TURP), use in trans rectal prostate ultrasound, biopsy, and radiation treatment.
11. A method of providing therapy to a patient, the method comprising the use of a medical device for intra-body conveyance, the medical device including a host structure defining an interior area and at least one power supply.
12. The method of claim 11 wherein the at least one power supply is charged through induction charging.
13. The method of claim 11, wherein the host structure comprises at least one of a clinically inert material, a sterilizable material, an elastomeric material, a chemically reactive material, a chemically inert material, a disintegrable material, a dissolvable material, and a collapsible material and a material having physical and chemical properties to withstand exposure to bodily fluids for a predetermined period of time.
14. The method of claim 11 wherein the at least one power supply is charged through ultrasonic charging.
15. A system comprising: a first medical device, a second medical device, and a tether, the first medical device including a first host structure defining a first interior area, and a first power supply, the second medical device including a second host structure defining a second interior area, and a second power supply, wherein the tether connects the first power supply to the second power supply, thereby allowing the transfer of power from the first power supply to the second power supply.
16. The system of claim 15, wherein the first and second host structures each have a diameter of about 25mm and a length of about 75mm.
17. The system of claim 15, wherein the first medical device is located inside a patient’s body and the second medical device is located outside the patient’s body.
PCT/US2019/033475 2018-05-22 2019-05-22 Power supplies and methods of using miniaturized intra-body controllable medical device WO2019226744A1 (en)

Applications Claiming Priority (2)

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