WO2019144187A1 - Apparatus and method for injecting material into organic tissue - Google Patents
Apparatus and method for injecting material into organic tissue Download PDFInfo
- Publication number
- WO2019144187A1 WO2019144187A1 PCT/AU2019/050047 AU2019050047W WO2019144187A1 WO 2019144187 A1 WO2019144187 A1 WO 2019144187A1 AU 2019050047 W AU2019050047 W AU 2019050047W WO 2019144187 A1 WO2019144187 A1 WO 2019144187A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- organic tissue
- cannula
- skin
- reservoir
- skin surface
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/48—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for varying, regulating, indicating or limiting injection pressure
- A61M5/484—Regulating injection pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/329—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles characterised by features of the needle shaft
- A61M5/3291—Shafts with additional lateral openings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
- A61M5/1454—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons spring-actuated, e.g. by a clockwork
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/16804—Flow controllers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/16831—Monitoring, detecting, signalling or eliminating infusion flow anomalies
- A61M5/16836—Monitoring, detecting, signalling or eliminating infusion flow anomalies by sensing tissue properties at the infusion site, e.g. for detecting infiltration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3129—Syringe barrels
- A61M5/3137—Specially designed finger grip means, e.g. for easy manipulation of the syringe rod
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
- A61M5/31515—Connection of piston with piston rod
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/46—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for controlling depth of insertion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/91—Injection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/35—Fat tissue; Adipocytes; Stromal cells; Connective tissues
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/925—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of animal origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M2005/2006—Having specific accessories
- A61M2005/2013—Having specific accessories triggering of discharging means by contact of injector with patient body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M2005/2026—Semi-automatic, e.g. user activated piston is assisted by additional source of energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M2005/2073—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3114—Filling or refilling
- A61M2005/3115—Filling or refilling spring-assisted
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3128—Incorporating one-way valves, e.g. pressure-relief or non-return valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3129—Syringe barrels
- A61M5/3137—Specially designed finger grip means, e.g. for easy manipulation of the syringe rod
- A61M2005/3139—Finger grips not integrally formed with the syringe barrel, e.g. using adapter with finger grips
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M2005/3201—Coaxially assembled needle cannulas placed on top of another, e.g. needles having different diameters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/0021—Special media to be introduced, removed or treated removed from and reintroduced into the body, e.g. after treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/08—Lipoids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/09—Body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/13—General characteristics of the apparatus with means for the detection of operative contact with patient, e.g. lip sensor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
- A61M2205/3334—Measuring or controlling the flow rate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/16877—Adjusting flow; Devices for setting a flow rate
- A61M5/16881—Regulating valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M5/204—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically connected to external reservoirs for multiple refilling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Definitions
- This invention relates to an apparatus and method for injecting material into organic tissue, and in particular, but not exclusively to an apparatus and method for injecting fat cells or dermal fillers through the skin and into the subcutaneous tissue of humans.
- the cell transfer process involves the accurate dispensing of small numbers of living cells into a large number of sites in the area being treated.
- the invention may broadly be said to consist in an apparatus for injecting material into organic tissue through a layer of skin, the apparatus having;
- a reservoir for holding a quantity of the material • a reservoir for holding a quantity of the material, ⁇ a cannula with at least one outlet adjacent to a free end of the cannula and through which the material from the reservoir is injected into the organic tissue, and
- the skin surface sensing means controls the rate at which material is expelled from the cannula and into the organic tissue as the free end of the cannula is moved from the first depth and to the second depth.
- the apparatus is configured such that the rate at which material is expelled through the or each outlet is proportional to the rate at which the free end of the cannula is moved through the organic tissue.
- the skin surface sensing means includes a sensing member having a sensing face configured contact the surface of the skin covering the organic tissue.
- the sensing face of the sensing member contacts the surface of the skin covering the organic tissue after the free end of the cannula is inserted through the surface of the skin, and when the outlet of the cannula reaches the said first depth.
- the sensing face of the sensing member remains butted against the surface of the skin while the cannula is pushed further into the organic tissue.
- the sensing member is mechanically linked to a plunger system of the injection apparatus.
- the skin surface sensing means is coupled to a plunger of the plunger system, and the plunger is configured to push material out of the reservoir and through the or each outlet.
- the skin surface sensing means includes an elongate member having a first end which includes the sensing member and a second end that is connected to the plunger.
- the elongate member of the skin surface sensing means is in the form of a tubular sleeve situated about the cannula.
- the apparatus includes a first biasing means that is configured to move the skin surface sensing means towards an extended position relative to a body of the apparatus.
- the body includes a cylinder which forms the reservoir of the apparatus.
- movement of the body toward the organic tissue, and/or initial penetration of the free end of the cannula through a hole in the skin and into the organic tissue causes the cannula to retract a predetermined amount relative to the body and to close a valve between the reservoir and a material supply line.
- continued movement of the body toward the organic tissue pushes a free end of the skin surface sensing means toward the skin surface about a hole in the skin surface through which the cannula has penetrated.
- the rate at which material is pushed out through the or each outlet hole is linked to the rate at which the cannula is pushed into the organic tissue.
- the apparatus is connectable to a bulk supply of material via a flexible supply tube.
- material flows from the bulk supply and into the reservoir when the valve is open and the skin surface sensing means is moving away from the body of the apparatus.
- the apparatus includes a second biasing means that is configured to move the cannula toward an extended position relative to the body.
- the first biasing means is in the form of a spring situated within a cylindrical housing that is connected to the skin surface sensing means.
- the apparatus further includes a handle that is connected to the body or which is a part of the body.
- the invention may broadly be said to consist in a method of injecting material into organic tissue using an injection apparatus, including the steps of;
- the skin surface sensing means controls the rate at which material is expelled from the reservoir and into the organic tissue via the cannula.
- the skin surface sensing means includes a sensing member having a sensing face configured contact the skin covering the organic tissue.
- the sensing face of the sensing member remains butted against the skin surface while the cannula is pushed into the organic tissue.
- the sensing member is mechanically linked to a plunger system of the injection apparatus.
- the rate at which material is expelled from the cannula is proportional to the rate at which the cannula is moved into the organic tissue.
- the invention may also broadly be said to consist in the parts, elements and features referred to or indicated in the specification of the application, individually or collectively, and any or all combinations of any two or more of the parts, elements or features, and where specific integers are mentioned herein which have known equivalents, such equivalents are incorporated herein as if they were individually set forth.
- FIGURE 1 is a longitudinal cross sectional view of a first example of an apparatus for injecting material into organic tissue according to the present invention
- FIGURE 2 is a longitudinal cross sectional view of the apparatus (first example) in a compressed state
- FIGURE 3 is an enlarged cross sectional view showing the end of a cannula of the apparatus (first example),
- FIGURE 4 is an enlarged cross sectional view showing a reservoir section of the apparatus (first example) and defining a detail area“A”,
- FIGURE 5 is an enlarged cross sectional view showing a main return spring of the apparatus (first example),
- FIGURE 6 is an enlarged cross sectional view of the detail area“A” defined in
- FIGURE 7 is an enlarged view of an inlet end of an alternative cannula design
- FIGURE 8 is an enlarged view of an optional join in the cannula
- FIGURE 9 is a longitudinal cross sectional view of a second example of an apparatus for injecting material into organic tissue according to the present invention.
- FIGURE 10 is a cross sectional view of a handle of the apparatus (second example)
- FIGURE 11 is a cross sectional view of a reservoir of the apparatus (second example)
- FIGURE 12 is a side elevation view of a cannula of the apparatus (second example).
- FIGURE 13 is a cross sectional view of a movable valve member of the apparatus
- FIGURE 14 is a cross sectional view of a cylindrical housing of the apparatus
- FIGURE 15 is a partial cross sectional view of an elongate member of the apparatus
- the apparatus (11) was designed for use in injecting material such as fat cells, fluids such as tumescent (used as a local anaesthetic in liposuction), dermal filler or stem cells into organic tissue.
- the apparatus (11) is typically used in cosmetic surgery to insert filler material into areas such as the face, legs, buttocks and breasts.
- the apparatus (11) has a reservoir (13) for holding a quantity of filler material, and a cannula (15) through which the material from the reservoir (13) is injected into organic tissue.
- the cannula (15) has one outlet (17) that is situated adjacent to a free end of the cannula (15).
- a fixed end of the cannula (15) is situated within the reservoir (13) and includes three inlet holes (18) through which the material can enter the cannula (15).
- the apparatus (11) also includes a skin surface sensing means (19) which will be described in further detail below.
- the apparatus (11) is configured to distribute the material into the organic tissue between a first depth in the organic tissue from the surface of the skin and a second depth in the organic tissue from the surface of the skin.
- the skin surface sensing means (19) is used to control the rate at which material is expelled from the cannula (15) and into the organic tissue as the free end of the cannula (15) is moved from the first depth and to the second depth.
- the rate at which material is expelled through the outlet (17) is proportional to the rate at which the free end of the cannula (17) is moved through the organic tissue.
- the skin surface sensing means (19) includes a sensing member (21) having a sensing face (23) configured contact the surface of the skin covering the organic tissue.
- the sensing face (23) of the sensing member (21) contacts the surface of the skin covering the organic tissue after the free end of the cannula (15) is inserted through a hole in the surface of the skin.
- the hole in the surface of the skin is generally produced by first pricking the skin with a sharp needle.
- the sensing face (23) of the sensing member (21) remains butted against the surface of the skin while the cannula (15) is pushed further into the organic tissue.
- the sensing member (21) is mechanically linked to a plunger system (25) associated with the reservoir (13) of the injection apparatus (11).
- the skin surface sensing means (19) is coupled to a plunger (27) of the plunger system (25) and the plunger (27) is situated within the reservoir (13) and is configured to push material out of the reservoir (13) and along the length of the cannula (15) and through the outlet (17) into the organic tissue.
- the skin surface sensing means (19) includes an elongate member (29) having a first end (31) which includes the sensing member (21) and a second end (33) that is connected to the plunger (27).
- the elongate member (29) is in the form of a tubular sleeve that is situated about the cannula (15) and which slides longitudinally relative to the cannula (15).
- the apparatus (11) further includes a first biasing means in the form of a first coil spring (35) that is configured to move the skin surface sensing means (19) towards an extended position relative to a body (37) of the apparatus (11).
- the body (37) includes a barrel or cylinder which forms the reservoir (13) of the apparatus (11).
- the apparatus (11) further includes a handle (39) that is rigidly connected to the cylinder that forms the reservoir (13).
- the first coil spring (35) is situated within a cylindrical housing (41).
- the cylindrical housing (41) is open at one end and includes a bulkhead (43) at an opposite end.
- the open end of the cylindrical housing (41) fits over the cylinder or barrel that forms the reservoir (13), while leaving space for the first coil spring (35) to fit and move between the outside diameter of the cylinder that forms the reservoir (13) and the inside diameter of the cylindrical housing (41).
- the first coil spring (35) is a compression spring that is compressed between a circumferential ridge (45) about the reservoir (13) and the bulkhead (43) of the cylindrical housing (41).
- the cylindrical housing (41) is connected to the skin surface sensing means (19) via a threaded joint between the bulkhead (43) and the elongate member (29).
- the tubular sleeve of the elongate member (29) slides into the body (37) along the cannula (15) the first coil spring (35) is compressed.
- the apparatus (11) is connectable to a bulk supply of material via a flexible material supply tube (not shown).
- a flexible material supply tube (not shown).
- movement of the body (37) toward the organic tissue, and/or initial penetration of the free end of the cannula (15) through a hole in the skin and into the organic tissue causes the cannula (15) to retract a predetermined amount relative to the body (37) and thereby to close a valve (47) situated between the reservoir (13) and the material supply tube.
- the valve (47) is situated within the handle (39) and the apparatus further includes a second biasing means in the form of a second coiled compression spring (49) that is configured to move the cannula (15) a short distance toward an extended position relative to the body (37).
- the valve (47) includes a valve body (51) that is attached to the reservoir (13), and also includes a movable valve member (53).
- the movable valve member (53) is connected to the cannula (15) via a threaded joint, and the movable valve member (53) is moved by movement of the cannula (15). Movement of the movable valve member (53) relative to the valve body (51) either opens or closes a flow passage through the valve (47).
- the compression spring (49) is compressed when the cannula (15) initially retracts, and moves the movable valve member (53) away from the reservoir (13), and the valve (47) is being closed.
- the rate at which material is pushed out through the outlet hole (17) and into the organic tissue is linked to the rate at which the cannula (15) is being pushed into the organic tissue, thereby producing an even spread of the material within the organic tissue between the first depth and the second depth.
- the reservoir (13) is replenished when material is drawn from the bulk supply and flows into the reservoir (13). This happens after the second biasing member (49) pushes the cannula (15) a short distance out of the body (37), thereby moving the movable valve member (53) toward the reservoir (13) and opening the valve (47).
- the material is drawn into the reservoir (13) through the valve (47), as the skin surface sensing means (19) is moved away from the body (37) by the first coil spring (35), which in turn drags the plunger (27) along the reservoir (13) to create a suction to help draw the material into the reservoir (13).
- the inlet holes (18) which allow material to enter into an internal bore of the cannula (15) are slightly larger than in than those shown in Figure 4.
- the reason for the increase in size is to allow material such as fat cells to flow into the cannula (15) with less resistance and therefore less stress on the cells.
- the freer flow of material into the cannula (15) also reduces strain on the operator.
- the inlet holes (18) are each elliptically shaped, with a major axis of the elliptical shape being two millimetres long and a minor axis of the elliptical shape being one millimetre long.
- the inlet holes (18) pass all the way through the cannula (15).
- the three inlet holes (18) are not aligned with each other, but rather each successive hole is indexed about the circumference of the cannula (15) with respect to the other inlet holes.
- a principal axis of each inlet hole (18), in a direction through the cannula (15), and when viewed from either end of the cannula (15), is aligned at sixty degrees to a principal axis of the other two inlet holes (18).
- the sensing member (21) (or the elongate member (29)) can be made up of two or more lengths that are joined end to end, and Figure 8 shows an optional bayonet style joint (55) that can be used to join adjacent lengths of the sensing member (21).
- This construction method allows a longer cannula (15) to be used if required, to allow material to be injected to a greater depth in the organic tissue.
- the apparatus (111) is a development of the first example (11) described above, and incorporates a number of features to improve the performance, primarily by improving flow and preventing leakage from the reservoir.
- the apparatus (111) has a reservoir (113) for holding a quantity of material, and a cannula (115) through which the material from the reservoir (113) is injected into organic tissue.
- the cannula (115) is approximately 280 to 300 millimetres long and has an outlet (117) that is situated adjacent to a free end (114) of the cannula (115).
- a fixed end (116) of the cannula (115) is situated within the reservoir (113) and material is pushed into the cannula (115) from the reservoir through three inlet holes (118) that are situated adjacent the fixed end (116) of the cannula (115).
- Each of the inlet holes (118) pass all the way through the cannula (115) and they intersect and communicate with an internal longitudinal passageway of the cannula (115).
- Each inlet hole (118) is elliptical in shape, a principal axis of each elliptical shape being aligned with a principal axis of the cannula.
- the cannula (115) has a diameter of approximately 1.8 millimetres, and a longitudinal bore or passageway having a diameter of approximately 0.8 millimetres, and each elliptical shaped inlet hole (118) is approximately two millimetres long and one millimetre wide.
- each inlet hole (118) of the cannula (115) of this second example of an apparatus (111) are not aligned with each other, but rather are aligned in spiralled arrangement. Due to the spiral arrangement, each successive hole (118) is indexed about a circumference of the cannula (115) with respect to the other inlet holes. And in this example, a principal axis of each inlet hole (118), in a direction through the cannula (115), and when viewed from either end of the cannula (115), is aligned at sixty degrees to a principal axis of the other two inlet holes (118).
- the fixed end (116) of the cannula (115) includes an externally threaded ferrule that mates with an internal thread on an outlet end (155) of a movable valve member (153) of a refill valve (147).
- the cannula (115) is mechanically fastened to the movable valve member (153) and can be used to move the movable valve member (153) to close the refill valve (147), to allow the reservoir (113) to be pressurised by the movement of the plunger (127).
- a middle section of the cannula (115) is situated within an elongate guide member (129).
- the elongate guide member (129) includes an elongate tube (130) which acts as a tubular sleeve and as a guide for the cannula (115) to move within.
- the elongate tube (130) has an internal diameter of approximately two millimetres that slides over and moves along the middle section of the cannula (115).
- the elongate guide member (129) also includes skin sensing face (123) at a first or free end (131), and a plunger (127) at a second or enclosed end (133).
- the plunger (127) is mated to the elongate tube (130) using a threaded connection, and the joint also includes a fillet weld to help seal the joint and to prevent inadvertent loosening of the joint.
- the plunger (127) also includes external seal grooves (159) about its circumference that allow seals such as O-rings to be used to create a leak resistant joint between the plunger (127) and an internal diameter of the reservoir (113).
- the elongate guide member (129) also has a bulkhead section (143) that is a part of the elongate tube (130) and is situated approximately midway between the first end (131) and the second end (133), but closer to the second end (133) than the first end (131).
- the elongate guide member (129) is approximately two hundred and ten millimetres long and the bulkhead section (143) is situated approximately eighty millimetres from the second end (133).
- the bulkhead section (143) of the elongate tube (130) is circular in shape and includes an external thread about its circumference.
- the external thread of the bulkhead section (143) mates with an internal thread on a fixed end (187) of a cylindrical housing (141).
- the elongate guide member (129) is mechanically fastened to the cylindrical housing (141), and movement of the elongate guide member (129) produces a similar movement of the cylindrical housing (141).
- the cylindrical housing (141) comprises a tube that is approximately eighty millimetres long and has an inside diameter of approximately twenty millimetres, and has a threaded section at each end.
- the cylindrical housing (141) is configured to fit over the reservoir (113) and to slide along its length.
- the apparatus (111) comprises two main assemblies that can move in a longitudinal sliding motion relative to each other.
- a first main part, or body (137) comprises the reservoir (113) and a handle (139).
- the second main part, or slide (157) comprises the cylindrical housing (141) and the elongate member (129).
- the slide (157) slides relative to the body (137) when the apparatus (111) is in use.
- a third main part of the apparatus (111) is the cannula (115) which is connected to the body (137) via a movable connection provided by the refill valve (147).
- the cannula (115) is supported along a part of its length by the slide (157), while at the same time being able to move longitudinally relative to the slide (157).
- Both the reservoir (113) and the handle (139) are essentially cylindrically shaped housings.
- the handle (139) is approximately one hundred and thirty millimetres long and has an outside diameter of approximately eighteen millimetres. The length of one hundred and thirty millimetres is helpful in making the handle (139) easy to grasp and to control movement of the apparatus (111) when in use.
- a free end (161) of the handle (139) includes an opening (163) through which a refill tube can be inserted to provide a supply of material to the reservoir (113) via the refill valve (147).
- a fixed end (165) of the handle (139) includes an internal thread that is configured to mate with an external thread on a fixed end (167) of the reservoir (113). In this way the handle (139) is mechanically fastened to the reservoir (113) to form the body (137) of the apparatus (111).
- the slide section (157) is initially mated to the body section (137) by inserting the plunger (127) of the slide section (157) into a free end (169) of the reservoir (113) of the body section (137).
- the cylindrical housing (141) begins to telescope over the outside diameter of the reservoir (113).
- the mating process further involves rotating the cylindrical housing (141) relative to the reservoir (113) to allow an internal thread on a free end (189) of the cylindrical housing (141) to engage with, and to move over, an externally threaded circumferential band or ridge (145) that is situated adjacent the free end (169) of the reservoir (113).
- the internal thread on the free end of the cylindrical housing (141) has passed fully over the externally threaded band (145) of the reservoir (113), and the cylindrical housing (141) can move or be telescoped over a greater part of the length of the reservoir (113).
- movement of the slide section (157) relative to the body section (137), and towards the handle (139) causes the plunger (127) to move up the cylinder (113) with the result that material within the cylinder (113) is pressurised and is caused to flow through the inlet holes (118) and into the cannula (115).
- a first coil spring (135) is a compression spring which is situated within the cylindrical housing (141), with a first end butted against a lip (185) on the fixed end of the cylindrical housing (141), and with a second end of the spring (135) butted against the free end (169) of the reservoir (113).
- the first spring (135) biases the slide section (157) in a direction away from the handle (139) of the body section (137).
- the slide section (157) can be pushed onto the body section (137) until the first spring (135) is fully compressed.
- the plunger (127) is situated adjacent the free end (169) of the reservoir (113), and when the first spring (135) is fully compressed the plunger (127) is situated adjacent the fixed end (167) of the reservoir (113).
- the apparatus (111) is relatively easy to use compared to prior art injecting devices because it includes a skin surface sensing means (119) that controls the rate at which material is injected into organic tissue.
- the skin surface sensing means (119) comprises a skin surface sensing member (121) which is essentially the first, or free end (131) of the elongate tube (130).
- the free end (131) of the elongate tube (130) includes a sensing face (123).
- the free end (114) of the cannula (115) is inserted through a small incision that is made in the skin of a client who is receiving filler material.
- the sensing face (123) of the skin surface sensing means (119) will contact the skin.
- the slide section (157) of the apparatus (111) is held back due to the contact between the sensing face (123) and the skin surface of the client. This causes the slide section (157) to move relative to the body section (137), compressing the first spring (135).
- the plunger (127) is progressively moved up the reservoir (113) causing material to be dispensed out of the cannula (115) and into the tissue.
- the amount of material that is dispensed out of the cannula (115) is relative to the distance moved by the cannula (115) into the tissue.
- the distance that the cannula (115) moves into the tissue relates directly to the distance that the plunger (127) is caused to move within the reservoir (113), and the distance that the plunger (127) moves relates directly to the volume of material that is pushed out of the reservoir (113) and into the tissue.
- the reservoir (113) of the injecting apparatus (111) is refilled via the refill valve (147).
- the refill valve (147) is operated by pushing the cannula (115) toward the handle (139) against the force of a second compression spring (149).
- One end of the second spring (149) butts against a flange (171) of the movable valve member (153), and an opposite end of the second spring (149) butts against a shoulder (173) formed in the inside diameter of the handle (139).
- the movable valve member (153) includes an internal passage (177) which is an internal passageway which runs along the length of the valve member (153) from a connection end (179) that is configured to mate with a refill line, to an outlet end (181) where a valve outlet aperture (175) is situated.
- the second spring (149) biases the movable valve member (153) toward a‘valve open’ position in which the valve outlet aperture (175) is situated within the chamber of the reservoir (113) and is not covered by a cylindrically shaped valve body (151). In this position it is possible to refill the reservoir (113) by pushing material into the reservoir through the refill valve (147), or by drawing or sucking material into the reservoir (113) by pulling the slide section (159) away from the handle (139), or by allowing the first spring (135) to push the slide section (159) away from the handle (139), or by a combination of these methods.
- the cylindrically shaped valve body (151) is essentially a length of tubing, approximately ten millimetres long and nine millimetres in diameter, that is formed as an extension of the reservoir (113), being situated at, and extending from, the fixed end of the reservoir (113).
- the axis of the valve body (151) is aligned with the axis of the reservoir (113).
- the movable valve member (153) has an O-ring groove (183) situated about its outer diameter for a seal or O-ring to minimise leakage between the outside diameter of the valve member (153) and the inside diameter of the valve body (151).
- the cannula (115) when the cannula (115) is being inserted into organic tissue, the cannula (115) is initially moved back toward the handle (139) causing the movable valve member (153) to move in the same direction. This initial backward movement of the cannula (115) compresses the second spring (149) and closes the refill valve (147) by positioning the valve outlet aperture (175) within the valve body (151) where the valve outlet aperture (175) is closed off by the valve body (151).
- the plunger (127) is then able to pressurise the inside of the reservoir to dispense material out through the outlet (117) as the free end (114) of the cannula (115) moves deeper into the tissue, and the slide section (157) is pushed toward the handle (139).
- material is dispensed out through the outlet (117) in a controlled manner, with the rate at which material is dispensed being proportional to the rate at which the outlet (117) is moved from a starting or first depth to a second or final depth within the organic tissue in which the filler material is being deposited.
- the method of injecting material into organic tissue using the first example of an apparatus (11) can be summarised as follows; ⁇ the reservoir (13) is initially filled from a bulk supply of suitable material through the valve (47) (this is the configuration shown in Figure 1),
- the cannula (15) is inserted through a hole in the skin covering the organic tissue and the cannula is initially retracted a small amount into the body (37) and closes the valve (47), ⁇ the cannula (15) is pushed a short distance through the skin until the skin surface sensing means (19) determines that the cannula (15) has reached the first depth, the free end of the cannula (15) is pushed into the organic tissue from the first depth to the second depth further while the skin surface sensing means (19) senses the depth of penetration of the cannula (15) from the surface of the skin and into the organic tissue,
- the skin surface sensing means (19) controls the rate at which material is expelled from the reservoir and into the organic tissue via the cannula as the cannula (15) is pushed into the organic tissue from the first depth to the second depth
- the method of operation of the second example of an apparatus (111) is essentially the same as the method of operation of the first example of an apparatus (11) described herein.
- the parts of the second example have similar item numbers (with a“1” in front) to their equivalent parts in the first example, that is a part with item number (53) in the first example is numbered (153) in the second example.
- the similarly numbered items can be used in the method outlined herein to define the method of operation of the apparatus (111) of the second example.
- the skin surface sensing, or the amount of penetration of the cannula into the tissue is carried out mechanically.
- skin surface sensing, or the amount of penetration of the cannula into the tissue could be determined by other means, for example optical sensing, ultra sound sensing or other imaging techniques and the rate at which material is expelled from the cannula could be controlled electronically using a microprocessor and an electrically driven actuator to drive the plunger.
- the cannula in the examples described includes a single outlet. It is envisaged that the cannula could be provided with additional outlets, for example an outlet on the opposite side of the cannula, if desired.
- the apparatus (l l or l l l) is envisaged primarily for use in injecting fat cells, stem cells or dermal fillers into humans, however it is envisaged that the apparatus could be used to inject material into the tissue of animals or a range of other living organisms including plant life if desired.
- the cannula can have multiple outlet holes, for example three outlet holes arranged in a spiralled alignment.
- At least the preferred form of the inventi on provides an apparatus and/or method for injecting material into organic tissue which is simple and low cost, and easy to operate, and which can distribute material evenly within the organic tissue without requiring great technical skill to operate.
- the operation of the apparatus (11) or (111) could be considered semiautomatic in that the operator simply has to insert the cannula at any desired rate and the apparatus automatically adjusts the rate at which material is injected to match the rate of insertion of the cannula.
- the apparatus as shown and described does not include any complex mechanical or electrical devices or circuitry and for this reason is lower cost, simpler to operate and maintain, and also simpler and more hygienic to clean.
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Virology (AREA)
- Zoology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Surgical Instruments (AREA)
Abstract
Description
Claims
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2019211466A AU2019211466A1 (en) | 2018-01-24 | 2019-01-24 | Apparatus and method for injecting material into organic tissue |
EP19743655.3A EP3743135A4 (en) | 2018-01-24 | 2019-01-24 | Apparatus and method for injecting material into organic tissue |
US16/963,927 US20210038808A1 (en) | 2018-01-24 | 2019-01-24 | Apparatus and method for injecting material into organic tissue |
CA3088805A CA3088805A1 (en) | 2018-01-24 | 2019-01-24 | Apparatus and method for injecting material into organic tissue |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2018900221A AU2018900221A0 (en) | 2018-01-24 | Apparatus and Method for Injecting Material into Organic Tissue | |
AU2018900221 | 2018-01-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2019144187A1 true WO2019144187A1 (en) | 2019-08-01 |
Family
ID=67395150
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/AU2019/050047 WO2019144187A1 (en) | 2018-01-24 | 2019-01-24 | Apparatus and method for injecting material into organic tissue |
Country Status (5)
Country | Link |
---|---|
US (1) | US20210038808A1 (en) |
EP (1) | EP3743135A4 (en) |
AU (1) | AU2019211466A1 (en) |
CA (1) | CA3088805A1 (en) |
WO (1) | WO2019144187A1 (en) |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB190905440A (en) * | 1909-03-06 | 1909-09-23 | Thomas Wade | Improvements in Hypodermic Syringes Adapted for Destruction of Warbles in Cattle and the like. |
US2888924A (en) * | 1958-02-25 | 1959-06-02 | Russell P Dunmire | Hypodermic syringes |
US3094987A (en) * | 1961-09-18 | 1963-06-25 | Dunmire Hannah | Hypodermic ampoules |
WO2012139593A2 (en) * | 2011-04-15 | 2012-10-18 | Rigshospitalet Copenhagen University Hospital | System and method for injecting a substance into a human body |
US20140088553A1 (en) * | 2008-04-02 | 2014-03-27 | Hugh Hetherington | Retractable plunger design for injection control device for proportional injection extraction during the syringe's insertion extraction |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10044383C2 (en) * | 2000-09-08 | 2003-02-06 | Disetronic Licensing Ag | Needle protector |
US7569035B1 (en) * | 2001-11-02 | 2009-08-04 | Meridian Medical Technologies, Inc. | Automatic injector with anti-coring needle |
-
2019
- 2019-01-24 CA CA3088805A patent/CA3088805A1/en active Pending
- 2019-01-24 US US16/963,927 patent/US20210038808A1/en active Pending
- 2019-01-24 WO PCT/AU2019/050047 patent/WO2019144187A1/en unknown
- 2019-01-24 AU AU2019211466A patent/AU2019211466A1/en active Pending
- 2019-01-24 EP EP19743655.3A patent/EP3743135A4/en active Pending
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB190905440A (en) * | 1909-03-06 | 1909-09-23 | Thomas Wade | Improvements in Hypodermic Syringes Adapted for Destruction of Warbles in Cattle and the like. |
US2888924A (en) * | 1958-02-25 | 1959-06-02 | Russell P Dunmire | Hypodermic syringes |
US3094987A (en) * | 1961-09-18 | 1963-06-25 | Dunmire Hannah | Hypodermic ampoules |
US20140088553A1 (en) * | 2008-04-02 | 2014-03-27 | Hugh Hetherington | Retractable plunger design for injection control device for proportional injection extraction during the syringe's insertion extraction |
WO2012139593A2 (en) * | 2011-04-15 | 2012-10-18 | Rigshospitalet Copenhagen University Hospital | System and method for injecting a substance into a human body |
Non-Patent Citations (1)
Title |
---|
See also references of EP3743135A4 * |
Also Published As
Publication number | Publication date |
---|---|
AU2019211466A1 (en) | 2020-09-03 |
EP3743135A1 (en) | 2020-12-02 |
US20210038808A1 (en) | 2021-02-11 |
CA3088805A1 (en) | 2019-08-01 |
EP3743135A4 (en) | 2021-11-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP3808916B2 (en) | Injectable substance delivery device | |
US4612010A (en) | Infiltration pump | |
US6004295A (en) | Catheters | |
US5370630A (en) | Device for injection of fluidic materials into body tissue | |
KR900008832B1 (en) | Back-rill syringe | |
EP1347796B1 (en) | Improved hypodermic needle and fluid injection device | |
US20060247578A1 (en) | Powered automatic injection device | |
US11167114B2 (en) | Set for peripheral nerve blocking | |
US20090149830A1 (en) | Intelligent needle technology for acupuncture and injection of cosmetic preparations subcutaneously | |
JP2016532496A5 (en) | ||
WO1994011042A1 (en) | Injector and use of the same | |
TW201242569A (en) | Hydraulic injection system for bone cement | |
CN105879159A (en) | Reusable injector and working method thereof | |
US20170014569A1 (en) | Gel delivery catheters, systems, and methods | |
US20170079630A1 (en) | Steerable Sheath Tube and Method for Occluding Atrial Septal Defect | |
US20170290985A1 (en) | Revolving multi-cartridge hypodermic syringe and method of use | |
US20090082730A1 (en) | Needle injection assembly | |
TW201728347A (en) | Drug injection device for skin treatment | |
US20210038808A1 (en) | Apparatus and method for injecting material into organic tissue | |
US11202862B2 (en) | Pressurized gas injection device and method | |
AU2004231230A1 (en) | Powered automatic injection device | |
JP7064013B2 (en) | Self-pumping syringe | |
KR20000023901A (en) | Air pressure type injection device for prevention of epidemic domestic animals | |
KR102107578B1 (en) | Constant velocity infusion device for painless syringe and painless sylinge having the same | |
KR101558549B1 (en) | Drug injection device |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 19743655 Country of ref document: EP Kind code of ref document: A1 |
|
ENP | Entry into the national phase |
Ref document number: 3088805 Country of ref document: CA |
|
NENP | Non-entry into the national phase |
Ref country code: DE |
|
ENP | Entry into the national phase |
Ref document number: 2019211466 Country of ref document: AU Date of ref document: 20190124 Kind code of ref document: A |
|
ENP | Entry into the national phase |
Ref document number: 2019743655 Country of ref document: EP Effective date: 20200824 |