WO2019117937A1 - Fluidic ejection controllers with selectively removable ejection boards - Google Patents

Fluidic ejection controllers with selectively removable ejection boards Download PDF

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Publication number
WO2019117937A1
WO2019117937A1 PCT/US2017/066612 US2017066612W WO2019117937A1 WO 2019117937 A1 WO2019117937 A1 WO 2019117937A1 US 2017066612 W US2017066612 W US 2017066612W WO 2019117937 A1 WO2019117937 A1 WO 2019117937A1
Authority
WO
WIPO (PCT)
Prior art keywords
ejection
fluidic ejection
fluidic
board
electrical
Prior art date
Application number
PCT/US2017/066612
Other languages
French (fr)
Inventor
Matthew David Smith
Dennis R. Esterberg
Jeffrey A. Nielsen
Original Assignee
Hewlett-Packard Development Company, L.P.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hewlett-Packard Development Company, L.P. filed Critical Hewlett-Packard Development Company, L.P.
Priority to US16/765,795 priority Critical patent/US11639056B2/en
Priority to PCT/US2017/066612 priority patent/WO2019117937A1/en
Publication of WO2019117937A1 publication Critical patent/WO2019117937A1/en

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B41PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
    • B41JTYPEWRITERS; SELECTIVE PRINTING MECHANISMS, i.e. MECHANISMS PRINTING OTHERWISE THAN FROM A FORME; CORRECTION OF TYPOGRAPHICAL ERRORS
    • B41J2/00Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed
    • B41J2/005Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed characterised by bringing liquid or particles selectively into contact with a printing material
    • B41J2/01Ink jet
    • B41J2/135Nozzles
    • B41J2/14Structure thereof only for on-demand ink jet heads
    • B41J2/1433Structure of nozzle plates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B41PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
    • B41JTYPEWRITERS; SELECTIVE PRINTING MECHANISMS, i.e. MECHANISMS PRINTING OTHERWISE THAN FROM A FORME; CORRECTION OF TYPOGRAPHICAL ERRORS
    • B41J2/00Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed
    • B41J2/005Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed characterised by bringing liquid or particles selectively into contact with a printing material
    • B41J2/01Ink jet
    • B41J2/17Ink jet characterised by ink handling
    • B41J2/175Ink supply systems ; Circuit parts therefor
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02Burettes; Pipettes
    • B01L3/0241Drop counters; Drop formers
    • B01L3/0268Drop counters; Drop formers using pulse dispensing or spraying, eg. inkjet type, piezo actuated ejection of droplets from capillaries
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B41PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
    • B41JTYPEWRITERS; SELECTIVE PRINTING MECHANISMS, i.e. MECHANISMS PRINTING OTHERWISE THAN FROM A FORME; CORRECTION OF TYPOGRAPHICAL ERRORS
    • B41J2/00Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed
    • B41J2/005Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed characterised by bringing liquid or particles selectively into contact with a printing material
    • B41J2/01Ink jet
    • B41J2/135Nozzles
    • B41J2/14Structure thereof only for on-demand ink jet heads
    • B41J2/14016Structure of bubble jet print heads
    • B41J2/14072Electrical connections, e.g. details on electrodes, connecting the chip to the outside...
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B41PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
    • B41JTYPEWRITERS; SELECTIVE PRINTING MECHANISMS, i.e. MECHANISMS PRINTING OTHERWISE THAN FROM A FORME; CORRECTION OF TYPOGRAPHICAL ERRORS
    • B41J2/00Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed
    • B41J2/005Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed characterised by bringing liquid or particles selectively into contact with a printing material
    • B41J2/01Ink jet
    • B41J2/135Nozzles
    • B41J2/14Structure thereof only for on-demand ink jet heads
    • B41J2/14201Structure of print heads with piezoelectric elements
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B41PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
    • B41JTYPEWRITERS; SELECTIVE PRINTING MECHANISMS, i.e. MECHANISMS PRINTING OTHERWISE THAN FROM A FORME; CORRECTION OF TYPOGRAPHICAL ERRORS
    • B41J29/00Details of, or accessories for, typewriters or selective printing mechanisms not otherwise provided for
    • B41J29/38Drives, motors, controls or automatic cut-off devices for the entire printing mechanism
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B41PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
    • B41JTYPEWRITERS; SELECTIVE PRINTING MECHANISMS, i.e. MECHANISMS PRINTING OTHERWISE THAN FROM A FORME; CORRECTION OF TYPOGRAPHICAL ERRORS
    • B41J2/00Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed
    • B41J2/005Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed characterised by bringing liquid or particles selectively into contact with a printing material
    • B41J2/01Ink jet
    • B41J2/135Nozzles
    • B41J2/14Structure thereof only for on-demand ink jet heads
    • B41J2002/14491Electrical connection
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices

Definitions

  • An assay is a process used in laboratory medicine, pharmacology, analytical chemistry, environmental biology, and molecular biology to assess or measure the presence, amount, or functional activity of a sample.
  • the sample may be a drug, a genomic sample, a proteomic sample, a biochemical substance, a cell in an organism, an organic sample, or other inorganic and organic chemical samples.
  • an assay is carried out by dispensing small amounts of fluid into multiple wells of a titration plate. The fluid in these wells can then be processed and analyzed. Such assays can be used to enable drug discovery as well as facilitate genomic and proteomic research.
  • FIG. 1 is a block diagram of a fluidic ejection controller with a removable ejection board, according to an example of the principles described herein.
  • FIG. 2 is an isometric view of a fluidic ejection system with a fluidic ejection controller with a removable ejection board, according to an example of the principles described herein.
  • Fig. 3 is a zoomed in view of a fluidic ejection controller with a removable ejection board in a fluidic ejection system, according to an example of the principles described herein.
  • FIG. 4 is an exploded view of a fluidic ejection controller with a removable ejection board in a fluidic ejection system, according to an example of the principles described herein.
  • FIG. 5 is a cross-sectional view of a fluid ejection device prior to installation into a fluidic ejection controller with a removable ejection board, according to an example of the principles described herein.
  • FIG. 8 is a cross-sectional view of a fluid ejection device following installation into a fluidic ejection controller with a removable ejection board, according to an example of the principles described herein.
  • FIG. 7 is an isometric view of a fluidic ejection device following installation info a fluidic ejection controller with a removable ejection board, according to an example of the principles described herein.
  • FIG. 8 is a view of an ejection board and a fluidic ejection device, according to an example of the principles described herein.
  • FIG. 9 is a view of another ejection board and a fluidic ejection device, according to an example of the principles described herein.
  • Fig. 10 is a bottom view of a fluidic ejection device, according to an example of the principles described herein.
  • An assay is a process used in laboratory medicine, pharmacology, analytical chemistry, environmental biology, and molecular biology to assess or measure the presence, amount, or functional activity of a sample.
  • the sample may be a drug, a genomic sample, a proteomic sample, a biochemical substance, a cell in an organism, an organic sample, or other inorganic and organic chemical samples.
  • an assay is carried out by dispensing small amounts of fluid into multiple wells of a titration plate. The fluid in these wells can then be processed and analyzed. Such assays can be used to enable drug discovery as well as facilitate genomic and proteomic research.
  • Such assays have been performed manually. That is, a user fills fluid into a single channel pipette, or a multi-channel pipette, and manually disperses a prescribed amount of fluid from the pipette into various wells of a titration plate. As this process is done by hand, it is tedious, complex, and inefficient. Moreover, it is prone to error as a user may misalign the pipette with the wells of the titration plate and/or may dispense an incorrect amount of fluid.
  • a controller activates an ejecting component that ejects an amount of fluid info the various wells of a titration plate.
  • the system also handles the titration plate to ensure proper alignment of the ejecting component and the wells of the titration plate.
  • the complexity and cost of these systems may prevent their more complete implementation.
  • the electrical connection between an ejecting head that ejects the fluid and a fluidic ejection system can be exposed, or involve complex motors to establish the electrical connections.
  • the electrical circuitry of such a fluidic ejection system may not be easily updateable. That is if a new, or different fluidic ejection device is developed, the fluidic ejection system may not be able to
  • the present systems and devices can be used to deposit fluid on other substrates or surfaces such as microscope slides, matrix assisted laser desorpfion/ionization (MALDI) plates, and microf!uidic chips among other substrates or surfaces.
  • substrates or surfaces such as microscope slides, matrix assisted laser desorpfion/ionization (MALDI) plates, and microf!uidic chips among other substrates or surfaces.
  • MALDI matrix assisted laser desorpfion/ionization
  • the present specification describes a fluidic ejection controller that is easily customizable to a specific fluidic ejection device.
  • the present specification describes a fluidic ejection controller that includes a firing board to generate firing signals, and to otherwise control the dispensing of fluid from the fluidic ejection device.
  • An ejection board is electrically coupled to the firing board.
  • the ejection board makes an electrical connection with the firing board and with an inserted fluidic ejection device.
  • the ejection board may be unique to the fluidic ejection device. That is, to pass electrical control signals to the fluidic ejection device, the ejection board has electrical pins that interface with electrical pads on the fluidic ejection device.
  • the pin pattern on the ejection board may correspond to, and be unique to, the fluidic ejection device.
  • the ejection board is removable from the fluidic ejection controller such that if a fluidic ejection controller is damaged, or a new fluidic ejection device is used, the ejection board, and not the entire firing board and/or system, could be replaced.
  • the fluidic ejection controller includes a firing board to pass electrical control signals for ejecting fluid from a fluidic ejection device.
  • An ejection board of the controller is electrically coupled to, and selectively removable from, the firing board to pass the electrical control signals to the fluidic ejection device.
  • Electrical pins are disposed on the ejection board in a pattern that matches a pattern of electrical pads on the fluidic ejection device. The electrical pins interface with corresponding electrical pads to pass the electrical control signals from the ejection board to the fluidic ejection device.
  • the present specification also describes a fluidic ejection system.
  • the system includes a fluidic ejection device that includes a reservoir disposed on a first side of a substrate and a fluid ejection die disposed on an opposite side of the substrate.
  • Each fluid ejection die includes an array of nozzles, where each nozzle includes an ejection chamber, an opening, and a fluid actuator disposed within the ejection chamber.
  • the fluidic ejection device also includes an electrical pad to receive electrical control signals.
  • the fluidic ejection system also includes a fluidic ejection controller that includes the firing board, the ejection board, and electrical pins disposed on the ejection board. In this example, the electrical pins are disposed in a pattern that matches a pattern of the electrical pads on the fluidic ejection device.
  • the present specification also describes a fluidic ejection controller in this example, the fluidic ejection controller includes the firing board, ejection board, and electrical pins disposed on the ejection board in a pattern that matches a pattern of electrical pads on the fluidic ejection device in this example, the electrical pins are disposed in a pattern unique to a corresponding fluidic ejection device and the ejection board is unique to the corresponding fluidic ejection device
  • firing board refers to a component of the fluidic ejection controller that controls a variety of fluidic ejection devices.
  • the firing board may pass signals that instruct an actuator of the ejecting head to activate and dispel an amount of fluid.
  • the term“ejection board” refers to a component of the fluidic ejection controller that corresponds to a particular one, or multiple fluidic ejection devices.
  • the ejection board may have an electrical pin count, and orientation that corresponds with, and is unique to a pattern of electrical pads on a fluidic ejection device.
  • Fig. 1 is a block diagram of a fluidic ejection controller (100) with a removable ejection board (104), according to an example of the principles described herein.
  • the fluidic ejection controller (100) is a component of a fluidic ejection system, which fluidic ejection system operates to eject fluid.
  • the fluid could be ejected into wells of a titration plate.
  • the fluidic ejection controller (100) receives control signals and routes them to the fluidic ejection device in some examples, the fluidic ejection controller (100) interacts with the fluidic ejection device as the fluidic ejection device is inserted into the fluidic ejection system.
  • the fluidic ejection controller (100) includes a firing board (102).
  • the firing board (102) includes the circuitry and other hardware to receive control signals and pass those control signals to the fluidic ejection device. Any number of control signals may be passed.
  • ejection signals may activate actuators on the fluidic ejection device to eject fluid therefrom.
  • Other types of signals include sensing signals to activate a sensor to collect data regarding the fluidic ejection device or a fluid passing through the fluidic ejection device.
  • a signal may activate a component of the fluidic ejection system and/or fluidic ejection device to electrically discharge fluid being ejected into the wells of the titration plate.
  • any number and type of control signals may be passed to the fluidic ejection device by the fluidic ejection controller (100) through the firing board (102).
  • the firing board (102) is used by multiple fluidic ejection devices. That is, the firing board (102) may not be unique to a particular fluidic ejection device and is therefore universal to various type of fluidic ejection devices.
  • the fluidic ejection controller (100) also Includes an ejection board (104) that is electrically coupled to the firing board (102) That is, via an electrical connection, control signals from the firing board (102) that originate within the fluidic ejection system, are passed through the ejection board (104).
  • the ejection board (104) receives incoming control signals and processes them for use with a fluidic ejection device to which the ejection board (104) corresponds. That is, the fluidic ejection device may include particular functionalities and/or may have electrical pads in a particular pattern.
  • the ejection board (104) may process control signals related to that particular functionality and may have electrical pins in the same pattern.
  • the ejection board (104) is also removable from the firing board (102). Accordingly, when an update to a fluidic ejection device occurs, or when a newly developed fluidic ejection device is released, rather than replacing the entire fluidic ejection controller (100) or fluidic ejection system of which it is a component, the ejection board (104) corresponding to the newly developed fluidic ejection device could be provided, and inserted into the fluidic ejection controller (100). Accordingly, the fluidic ejection controller (100) is thereby capable of update and can accommodate new, or different, fluidic ejection devices.
  • Electrical pins (108) are disposed on the ejection board (104). These electrical pins (106) interface with electrical pads on a fluidic ejection device installed in a fluidic ejection system. As described above, the ejection board (104) may be uniquely paired with a particular fluidic ejection device. In one example of this, the pattern of the electrical pins (106) may match with a pattern of the electrical pads on the fluidic ejection device. An example of such matched pairing is described below in connection with Figs. 8 and 9. Such a removable ejection board (104) with its electrical pins (106) disposed thereon enables user replacement of the electrical pins (106) without replacement of larger and more expensive components such as the firing board (102).
  • a user may change to an ejection board (104) with a different number, and/or different arrangement, of electrical pins (106).
  • the different quantity of electrical pins (106) can enable new functionality not present in the original ejection board (104), such as the addition of a closed-loop feedback
  • FIG. 2 is an isometric view of a fluidic ejection system (208) with a fluidic ejection controller (100) with a removable ejection board (Fig. 1 , 104), according to an example of the principles described herein in some examples, the fluidic ejection system (208) includes a fluidic ejection controller (100).
  • the fluidic ejection device (212) is inserted into the fluidic ejection controller (100). From the fluidic ejection device (212), fluid is ejected onto a surface, such as wells of a titration plate (210).
  • the fluidic ejection device (212) dispenses picoliter quantities of a target fluid into microtiter plates using disposable fluidic ejection device (212).
  • each fluidic ejection device (212) includes a fluidic ejection die that can rely on inkjet technology to eject fluid therefrom.
  • Such a fluidic ejection system (208) by using inkjet components such as ejection chambers, openings, and actuators disposed within the micro-fluidic ejection chambers, enable low-volume dispensing of fluids such as those used in life science and clinical applications.
  • Examples of such applications include dose-response titrations, polymerase chain reaction (PCR) miniaturization, microarray printing, drug-drug combination testing, drug repurposing, drug metabolism and pharmacokinetics (DMPK) dispensing and a wide variety of other life science dispensing.
  • PCR polymerase chain reaction
  • DMPK pharmacokinetics
  • the titration plate (210) may be any plate that receives a fluid ejected from the fluidic ejection device (212).
  • the titration plate (210) includes wells into which the fluid may be ejected.
  • FIG. 3 is a zoomed-in view of a fluidic ejection controller (100) with a removable ejection board (104) installed in a fluidic ejection system (Fig. 2,
  • Fig. 3 depicts the fluidic ejection controller (100) in an assembled state.
  • the ejection board (104) is disposed between the firing board (102) and the fluidic ejection device (212).
  • the ejection board (104) is modular to the firing board (102) and the fluidic ejection system (Fig 2, 208) as a whole. For example, screws or other connectors may mechanically fasten the ejection board (104) to the fluidic ejection system (Fig 2, 208). Electrical connectors on the ejection board (104) make contact with, or otherwise mate with,
  • Such a modular design allows for increased use of the fluidic ejection system (Fig. 2, 208) as the system is customizable to different fluidic ejection devices (212). That is, newly developed fluidic ejection devices (212) that may have different functionality or pad patterns, can be used by simply swapping out an old ejection board (104) for a different one to be used with the newly developed fluidic ejection device (212). Moreover, if electrical pins (106) become damaged, rather than replacing an entire firing circuitry, just the ejection board (104) may be replaced, thus reducing the cost of repair.
  • FIG. 3 depicts a single fluidic ejection device (212) being received info the fluidic ejection controller (100), multiple fluidic ejection devices (212) may be inserted therein.
  • multiple fluidic ejection dies may be formed in a substrate and inserted into the fluidic ejection controller (100).
  • FIG. 4 is an exploded view of a fluidic ejection controller (100) with a removable ejection board (104) installed in a fluidic ejection system (Fig. 2,
  • FIG. 4 clearly depicts the electrical connectors (414) on the firing board (102) and the corresponding electrical connectors (416) on the ejection board (104) that are coupled together to route signals from the firing board (102) to the ejection board (104) where they are conditioned for the fluidic ejection device (212) that is inserted, and that is uniquely paired to interface with the ejection board (104).
  • Fig. 4 also clearly depicts the electrical pins (106) and the electrical pads (420) that interface with one another when the fluidic ejection device (212) is installed into the fluidic ejection controller (100). Via this electrical connection, the fluidic ejection die of the fluidic ejection device (212) is activated to eject a corresponding fluid. That is, through this connection, the fluidic ejection die of the fluidic ejection device (212) receives electrical signals directing when, where, and how to eject an amount of fluid therefrom. In an example, the fluidic ejection device (212) may be moved relative to a titration plate (Fig.
  • the titration plate (Fig 2, 210) and/or the titration plate (Fig 2, 210) may be moved relative to the fluidic ejection device (212) such that placement of the fluidic ejection die over any portion of the titration plate (Fig 2, 210) and ejection of fluid from the fluidic ejection die allows an amount of fluid to be ejected into any number of wells in the titration plate (Fig. 2, 210).
  • the ejection of the fluid from the fluidic ejection die is directed by a controller of the system as described above.
  • the fluidic ejection controller (100) includes a guide mechanism (418) to align the fluidic ejection device (212) with the ejection board (104).
  • the guide mechanism (418) may have walls, and a portion of a floor that support, and guide, the fluidic ejection device (212) as it is slid into place.
  • FIG. 5 is a cross-sectional view of a fluid ejection device (212) prior to insertion into a fluidic ejection controller (Fig. 1 , 100) with a removable ejection board (104), according to an example of the principles described herein.
  • a fluidic ejection device (212) is positioned for fluidic ejection by sliding the fluidic ejection device (212) into electrical contact with the fluidic ejection controller (Fig. 1 , 100). For example, a user may grasp the fluidic ejection device (212), and slide it in a direction indicated by the arrow (522).
  • the electrical pins (106) Prior to installation, the electrical pins (106) are in an extended state.
  • the electrical pins (106) may be spring-loaded pins that are biased towards an extended position.
  • the electrical pins (106) retract into a housing in some examples, the leading edge of the fluidic ejection device (212) includes a bezel to deflect the electrical pins (106) into the housing upon insertion of the fluidic ejection device (212) into the fluidic ejection controller (Fig. 1 , 100). Without such a bezel, damage to the electrical pins (106) may occur as they come into contact with a vertical leading edge of the fluidic ejection device (212).
  • FIG. 6 is a cross-sectional view of a fluid ejection device (212) inserted into a fluidic ejection controller (Fig. 1 , 100) with a removable ejection board (104), according to an example of the principles described herein.
  • the fluidic ejection device (212) is fully seated within the fluidic ejection controller (100). That is, the electrical pins (106), now in a retracted state, are aligned with the electrical pads (Fig. 4 420) of the fluidic ejection device (212).
  • the electrical pins (106) now in a retracted state
  • the complexity of the fluidic ejection setup is reduced, as is the operation of the fluidic ejection system (Fig. 2, 208) as a whole.
  • the fluidic ejection controller (Fig. 1 , 100) as described herein provides for a sliding-in motion of the fluidic ejection device (212) info the fluidic ejection controller (Fig. 1 , 100) to establish an electrical connection. This can eliminate the use a powered electrical engagement mechanism, which is prone to breaking down, is more complex to operate, and is more costly to manufacture.
  • FIG. 7 is an isometric view of a fluidic ejection device (212) aligned with a fluidic ejection controller (Fig. 1 , 100) with a removable ejection board (Fig. 1 , 104), according to an example of the principles described herein.
  • Fig. 7 clearly depicts the electrical pins (106) in their retracted state, yet fully contacting the electrical pads (420).
  • the electrical pins (106) may be biased towards an extended position such that there is downward force of the electrical pins (106) against the electrical pads (420) thus ensuring a solid electrical connection
  • the fluidic ejection controller (Fig. 1 , 100) includes a connection indicator (724) which indicates a proper alignment of the fluidic ejection device (212) with the fiuidic ejection controller (Fig 1 , 100).
  • the connection indicator (724) may be a light-emitting diode (LED) disposed on a housing of the fluidic ejection system (Fig. 2, 208) that turns a particular color, or turns on, or flashes, when there is an electrical connection between the electrical pins (106) and the electrical pads (420)
  • Fig 7 also clearly indicates the reservoir (726) which holds the fluid to be ejected.
  • the reservoir (726) may be any void defined in the surface of the fluidic ejection device (212) that can hold an amount of fluid.
  • the reservoir (726) provides the fluid to a die coupled to the substrate and may be on an opposite side of the fluidic ejection device (212) as the fiuidic ejection die.
  • An example of a fluidic ejection die is depicted in Fig. 10.
  • a slot may be formed between the reservoir (726) and the fluidic ejection die to direct the fluid towards the fiuidic ejection die using gravitational forces.
  • the reservoir (726) is exposed such that a user can deposit fluid therein.
  • Fig. 8 is a planar view of an ejection board (104) and a fiuidic ejection device (212), according to an example of the principles described herein.
  • Fig. 8 depicts an underside view of the ejection board (104) with its corresponding electrical pins (106) that align with the electrical pads (420) and a top view of the fluidic ejection device (212) in some examples, the electrical pins (106) are disposed away from a leading edge of the fiuidic ejection controller (Fig. 1 , 100).
  • the ejection board (104) is unique to the particular fiuidic ejection device (212). More specifically, in some examples, the number and/or pattern of electrical pins (106) is unique to a particular fiuidic ejection device (212). As an example, the fluidic ejection device (212) of Fig. 8 has six electrical pads (420) in a particular pattern.
  • the ejection board (104) has the six electrical pins (106) arranged in the same pattern.
  • the fluidic ejection device (212) depicted in Fig. 9 has ten electrical pads (420) in a particular pattern.
  • the corresponding ejection board (104) has ten electrical pins (106) in the same pattern.
  • the fluidic ejection device (212) includes a substrate into which a reservoir (726) is formed.
  • the substrate may be any material, such as a monolithic thermoplastic material.
  • the thermoplastic material is doped with a non-conductive, metallic, inorganic compound.
  • a metal traces may be added to any surface of the substrate using a laser direct structuring (LDS) process.
  • LDS laser direct structuring
  • the substrate may be formed to allow a user to insert or otherwise interface the fluidic ejection device (212) with a fluidic ejection system (Fig. 2, 208).
  • the substrate may include a handle.
  • the handle allows a user to grip the fluidic ejection device (212) in order to place the fluidic ejection device (212) into the fluidic ejection system (Fig. 2, 2008)
  • the handle allows a user to touch, pick up, and move the fluidic ejection device (212) without contaminating the reservoir (726) or a fluid deposited therein.
  • FIG. 9 is a top view of another ejection board (104) and a fluidic ejection device (212), according to an example of the principles described herein.
  • the ejection board (104) and fluidic ejection device (212) have a different number, and pattern, of electrical pins (106) and electrical pads (420).
  • the additional pins (106) and electrical pads (420) may provide additional or different functionality.
  • the additional electrical connections can facilitate a closed-look feedback function such as sensing of die temperature and sensing a property of the fluid. This additional functionality may not have been available when a previous fluidic ejection device (212) was released.
  • FIG. 10 is a bottom view of a fluidic ejection device (212), according to an example of the principles described herein.
  • the reservoir (Fig. 7, 726) is fluidly coupled to a fluidic ejection die (1028) so that the fluid may be introduced to the fluidic ejection die (1028) for ejection into a number of the wells of the titration plate (Fig. 2, 210) as instructed by a fluidic ejection system (Fig. 2, 208).
  • the fluidic ejection die (1026) includes an array of nozzles (1028).
  • Each nozzle (1028) includes a number of components.
  • a nozzle (1028) includes an ejection chamber (1032) to hold an amount of fluid to be ejected, an opening (1030) through which the amount of fluid is ejected, and an actuator (1034), disposed within the ejection chamber (1032), to eject the amount of fluid through the opening (1030).
  • an actuator (1034) disposed within the ejection chamber (1032), to eject the amount of fluid through the opening (1030).
  • the relative size of the nozzle openings (1030) and the fluidic ejection die (1028) are not to scale, with the nozzles (1028) being enlarged for purposes of illustration.
  • the actuator (1034) may include a firing resistor or other thermal device, a piezoelectric element, or other mechanism for ejecting fluid from the ejection chamber (1032).
  • the actuator (1034) may be a firing resistor.
  • the firing resistor heats up in response to an applied voltage. As the firing resistor heats up, a portion of the fluid in the ejection chamber (1034) vaporizes to form a bubble. This bubble pushes fluid out the opening (1030) and onto the print medium.
  • the fluidic ejection die (1026) may be a thermal inkjet (TIJ) fluidic ejection die (1026).
  • the actuator (1034) may be a piezoelectric device. As a voltage is applied, the piezoelectric device changes shape which generates a pressure pulse in the ejection chamber (1032) that pushes the fluid out the opening (1030) and onto the print medium.
  • the fluidic ejection die (1026) may be a piezoelectric inkjet (P!J) fluidic ejection die (1026).
  • the fluidic ejection die (1026) may include fluidic channels and chambers through which the fluid placed in the reservoir (Fig 7, 726) may flow through and out of the nozzles (1028).
  • the fluidic ejection device (212) also includes electrical components on the front and back surfaces of the substrate.
  • the electrical components may be made of any electrically conductive material to allow for electrical signals to be sent between the fluidic ejection system (Fig. 2, 208), via the electrical pins (Fig. 1 , 106) on the ejection board (Fig. 1 , 104) and the fluidic ejection die (1026).
  • contact pads (Fig. 4, 420) may be included on the front surface of the substrate. The contact pads (Fig. 4, 420) provide for an electrically conducive interface between the fluidic ejection system (Fig. 2, 208) and the fluidic ejection device (212).
  • Vias may be formed in the fluidic ejection device (212) and are electrically coupled to the contact pads (Fig. 4, 420).
  • the vias may be any electrical connection that goes through the substrate and couples the
  • connection pads (Fig. 4, 420) to electrical components on the opposite side of the substrate.
  • the vias are coupled on the opposite side of the substrate to traces.
  • the traces may be coupled to the fluidic ejection die (1026) using wirebonds coupled between die pads of the fluidic ejection die (1026).
  • a fluidic ejection system (Fig. 2 208) via the firing board (Fig. 1, 102) and ejection board (Fig. 1, 104) may interface with the contact pads (Fig. 4, 420) defined on the front of the fluidic ejection device (212) in order to send electrical signals to the fluidic ejection die (1026) to cause the fluidic ejection die (1026) to, at least, eject an amount of fluid therefrom.

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Abstract

In one example in accordance with the present disclosure, a fluidic ejection controller is described. The fluidic ejection controller includes a firing board to pass electrical control signals for ejecting fluid from a fluidic ejection device. An ejection board of the fluidic ejection controller is electrically coupled to, and selectively removable from, the firing board to pass the electrical control signals to the fluidic ejection device. Electrical pins are disposed on the ejection board in a pattern that matches a pattern of electrical pads on the fluidic ejection device. The electrical pins interface with corresponding electrical pads to pass the electrical control signals from the ejection board to the fluidic ejection device.

Description

FLUIDIC EJECTION CONTROLLERS
WITH SELECTIVELY REMOVABLE EJECTION BOARDS
BACKGROUND
[0001] An assay is a process used in laboratory medicine, pharmacology, analytical chemistry, environmental biology, and molecular biology to assess or measure the presence, amount, or functional activity of a sample. The sample may be a drug, a genomic sample, a proteomic sample, a biochemical substance, a cell in an organism, an organic sample, or other inorganic and organic chemical samples. In general, an assay is carried out by dispensing small amounts of fluid into multiple wells of a titration plate. The fluid in these wells can then be processed and analyzed. Such assays can be used to enable drug discovery as well as facilitate genomic and proteomic research.
BRIEF DESCRIPTION OF THE DRAWINGS
[0002] The accompanying drawings illustrate various examples of the principles described herein and are part of the specification. The illustrated examples are given merely for illustration, and do not limit the scope of the claims.
[0003] Fig. 1 is a block diagram of a fluidic ejection controller with a removable ejection board, according to an example of the principles described herein.
[0004] Fig. 2 is an isometric view of a fluidic ejection system with a fluidic ejection controller with a removable ejection board, according to an example of the principles described herein. [0005] Fig. 3 is a zoomed in view of a fluidic ejection controller with a removable ejection board in a fluidic ejection system, according to an example of the principles described herein.
[0006] Fig. 4 is an exploded view of a fluidic ejection controller with a removable ejection board in a fluidic ejection system, according to an example of the principles described herein.
[0007] Fig. 5 is a cross-sectional view of a fluid ejection device prior to installation into a fluidic ejection controller with a removable ejection board, according to an example of the principles described herein.
[0008] Fig. 8 is a cross-sectional view of a fluid ejection device following installation into a fluidic ejection controller with a removable ejection board, according to an example of the principles described herein.
[0009] Fig. 7 is an isometric view of a fluidic ejection device following installation info a fluidic ejection controller with a removable ejection board, according to an example of the principles described herein.
[0010] Fig. 8 is a view of an ejection board and a fluidic ejection device, according to an example of the principles described herein.
[0011] Fig. 9 is a view of another ejection board and a fluidic ejection device, according to an example of the principles described herein.
[0012] Fig. 10 is a bottom view of a fluidic ejection device, according to an example of the principles described herein.
[0013] Throughout the drawings, identical reference numbers designate similar, but not necessarily identical, elements. The figures are not necessarily to scale, and the size of some parts may be exaggerated to more clearly illustrate the example shown. Moreover, the drawings provide examples and/or implementations consistent with the description; however, the description is not limited to the examples and/or implementations provided in the drawings. DETAILED DESCRIPTION
[0014] An assay is a process used in laboratory medicine, pharmacology, analytical chemistry, environmental biology, and molecular biology to assess or measure the presence, amount, or functional activity of a sample. The sample may be a drug, a genomic sample, a proteomic sample, a biochemical substance, a cell in an organism, an organic sample, or other inorganic and organic chemical samples. In general, an assay is carried out by dispensing small amounts of fluid into multiple wells of a titration plate. The fluid in these wells can then be processed and analyzed. Such assays can be used to enable drug discovery as well as facilitate genomic and proteomic research.
[0015] Such assays have been performed manually. That is, a user fills fluid into a single channel pipette, or a multi-channel pipette, and manually disperses a prescribed amount of fluid from the pipette into various wells of a titration plate. As this process is done by hand, it is tedious, complex, and inefficient. Moreover, it is prone to error as a user may misalign the pipette with the wells of the titration plate and/or may dispense an incorrect amount of fluid.
[0016] Some automated fluidic ejection systems have been developed to eject predetermined amounts of fluid into the wells of a titration plate in these examples, a controller activates an ejecting component that ejects an amount of fluid info the various wells of a titration plate. The system also handles the titration plate to ensure proper alignment of the ejecting component and the wells of the titration plate. However, the complexity and cost of these systems may prevent their more complete implementation. Moreover, the electrical connection between an ejecting head that ejects the fluid and a fluidic ejection system can be exposed, or involve complex motors to establish the electrical connections. Still further, the electrical circuitry of such a fluidic ejection system may not be easily updateable. That is if a new, or different fluidic ejection device is developed, the fluidic ejection system may not be able to
accommodate the fluidic ejection device
[0017] While specific reference is made to deposition of fluid into wells of a titration plate, the present systems and devices can be used to deposit fluid on other substrates or surfaces such as microscope slides, matrix assisted laser desorpfion/ionization (MALDI) plates, and microf!uidic chips among other substrates or surfaces.
[0018] Accordingly, the present specification describes a fluidic ejection controller that is easily customizable to a specific fluidic ejection device.
Specifically, the present specification describes a fluidic ejection controller that includes a firing board to generate firing signals, and to otherwise control the dispensing of fluid from the fluidic ejection device. An ejection board is electrically coupled to the firing board. The ejection board makes an electrical connection with the firing board and with an inserted fluidic ejection device. The ejection board may be unique to the fluidic ejection device. That is, to pass electrical control signals to the fluidic ejection device, the ejection board has electrical pins that interface with electrical pads on the fluidic ejection device. The pin pattern on the ejection board may correspond to, and be unique to, the fluidic ejection device. Moreover, the ejection board is removable from the fluidic ejection controller such that if a fluidic ejection controller is damaged, or a new fluidic ejection device is used, the ejection board, and not the entire firing board and/or system, could be replaced.
[0019] Specifically, the present specification describes a fluidic ejection controller. The fluidic ejection controller includes a firing board to pass electrical control signals for ejecting fluid from a fluidic ejection device. An ejection board of the controller is electrically coupled to, and selectively removable from, the firing board to pass the electrical control signals to the fluidic ejection device. Electrical pins are disposed on the ejection board in a pattern that matches a pattern of electrical pads on the fluidic ejection device. The electrical pins interface with corresponding electrical pads to pass the electrical control signals from the ejection board to the fluidic ejection device.
[0020] The present specification also describes a fluidic ejection system.
The system includes a fluidic ejection device that includes a reservoir disposed on a first side of a substrate and a fluid ejection die disposed on an opposite side of the substrate. Each fluid ejection die includes an array of nozzles, where each nozzle includes an ejection chamber, an opening, and a fluid actuator disposed within the ejection chamber. The fluidic ejection device also includes an electrical pad to receive electrical control signals. The fluidic ejection system also includes a fluidic ejection controller that includes the firing board, the ejection board, and electrical pins disposed on the ejection board. In this example, the electrical pins are disposed in a pattern that matches a pattern of the electrical pads on the fluidic ejection device.
[0021] The present specification also describes a fluidic ejection controller in this example, the fluidic ejection controller includes the firing board, ejection board, and electrical pins disposed on the ejection board in a pattern that matches a pattern of electrical pads on the fluidic ejection device in this example, the electrical pins are disposed in a pattern unique to a corresponding fluidic ejection device and the ejection board is unique to the corresponding fluidic ejection device
[0022] In summary, using such a fluidic ejection controller with a replaceable ejection board 1 ) is more robust in that it protects the electrical pins; 2) is more simple to operate based on a slide-in insertion motion which alleviates an electrical pin engagement mechanism such as a motor; 3) enables user- replacement of the electrical pin assembly on an ejection board without replacement of an entire firing board; 4) enables upgrade of the ejection board to an ejection board with a different number, or different arrangement, of electrical pins. The different electrical pins, when paired with corresponding electrical pads, can enable new functionality.
[0023] As used in the present specification and in the appended claims, the term“a number of or similar language is meant to be understood broadly as any positive number including 1 to infinity.
[0024] Further, as used in the present specification and in the appended claims, the term“firing board” refers to a component of the fluidic ejection controller that controls a variety of fluidic ejection devices. For example, the firing board may pass signals that instruct an actuator of the ejecting head to activate and dispel an amount of fluid.
[0025] Still further, as used in the present specification and in the appended claims, the term“ejection board” refers to a component of the fluidic ejection controller that corresponds to a particular one, or multiple fluidic ejection devices. For example, the ejection board may have an electrical pin count, and orientation that corresponds with, and is unique to a pattern of electrical pads on a fluidic ejection device.
[0026] Turning now to the figures, Fig. 1 is a block diagram of a fluidic ejection controller (100) with a removable ejection board (104), according to an example of the principles described herein. As described above, the fluidic ejection controller (100) is a component of a fluidic ejection system, which fluidic ejection system operates to eject fluid. For example, the fluid could be ejected into wells of a titration plate. To eject the fluid, the fluidic ejection controller (100) receives control signals and routes them to the fluidic ejection device in some examples, the fluidic ejection controller (100) interacts with the fluidic ejection device as the fluidic ejection device is inserted into the fluidic ejection system.
[0027] The fluidic ejection controller (100) includes a firing board (102). The firing board (102) includes the circuitry and other hardware to receive control signals and pass those control signals to the fluidic ejection device. Any number of control signals may be passed. For example, ejection signals may activate actuators on the fluidic ejection device to eject fluid therefrom. Other types of signals include sensing signals to activate a sensor to collect data regarding the fluidic ejection device or a fluid passing through the fluidic ejection device. As yet another example, a signal may activate a component of the fluidic ejection system and/or fluidic ejection device to electrically discharge fluid being ejected into the wells of the titration plate. While specific reference is made to particular control signals generated and/or passed by the firing board, any number and type of control signals may be passed to the fluidic ejection device by the fluidic ejection controller (100) through the firing board (102). In some examples, the firing board (102) is used by multiple fluidic ejection devices. That is, the firing board (102) may not be unique to a particular fluidic ejection device and is therefore universal to various type of fluidic ejection devices.
8 [0028] The fluidic ejection controller (100) also Includes an ejection board (104) that is electrically coupled to the firing board (102) That is, via an electrical connection, control signals from the firing board (102) that originate within the fluidic ejection system, are passed through the ejection board (104). The ejection board (104) receives incoming control signals and processes them for use with a fluidic ejection device to which the ejection board (104) corresponds. That is, the fluidic ejection device may include particular functionalities and/or may have electrical pads in a particular pattern. The ejection board (104) may process control signals related to that particular functionality and may have electrical pins in the same pattern.
[0029] The ejection board (104) is also removable from the firing board (102). Accordingly, when an update to a fluidic ejection device occurs, or when a newly developed fluidic ejection device is released, rather than replacing the entire fluidic ejection controller (100) or fluidic ejection system of which it is a component, the ejection board (104) corresponding to the newly developed fluidic ejection device could be provided, and inserted into the fluidic ejection controller (100). Accordingly, the fluidic ejection controller (100) is thereby capable of update and can accommodate new, or different, fluidic ejection devices.
[0030] Electrical pins (108) are disposed on the ejection board (104). These electrical pins (106) interface with electrical pads on a fluidic ejection device installed in a fluidic ejection system. As described above, the ejection board (104) may be uniquely paired with a particular fluidic ejection device. In one example of this, the pattern of the electrical pins (106) may match with a pattern of the electrical pads on the fluidic ejection device. An example of such matched pairing is described below in connection with Figs. 8 and 9. Such a removable ejection board (104) with its electrical pins (106) disposed thereon enables user replacement of the electrical pins (106) without replacement of larger and more expensive components such as the firing board (102). For example, a user may change to an ejection board (104) with a different number, and/or different arrangement, of electrical pins (106). The different quantity of electrical pins (106) can enable new functionality not present in the original ejection board (104), such as the addition of a closed-loop feedback
mechanism. This can be done without requiring a new version of the fluidic ejection system or a new firing board (102), which could be expensive, and time-consuming.
[0031] Fig. 2 is an isometric view of a fluidic ejection system (208) with a fluidic ejection controller (100) with a removable ejection board (Fig. 1 , 104), according to an example of the principles described herein in some examples, the fluidic ejection system (208) includes a fluidic ejection controller (100). The fluidic ejection device (212) is inserted into the fluidic ejection controller (100). From the fluidic ejection device (212), fluid is ejected onto a surface, such as wells of a titration plate (210). In some examples, the fluidic ejection device (212) dispenses picoliter quantities of a target fluid into microtiter plates using disposable fluidic ejection device (212). As will be described below, each fluidic ejection device (212) includes a fluidic ejection die that can rely on inkjet technology to eject fluid therefrom. Such a fluidic ejection system (208), by using inkjet components such as ejection chambers, openings, and actuators disposed within the micro-fluidic ejection chambers, enable low-volume dispensing of fluids such as those used in life science and clinical applications. Examples of such applications include dose-response titrations, polymerase chain reaction (PCR) miniaturization, microarray printing, drug-drug combination testing, drug repurposing, drug metabolism and pharmacokinetics (DMPK) dispensing and a wide variety of other life science dispensing.
[0032] The titration plate (210) may be any plate that receives a fluid ejected from the fluidic ejection device (212). The titration plate (210) includes wells into which the fluid may be ejected.
[0033] Fig 3 is a zoomed-in view of a fluidic ejection controller (100) with a removable ejection board (104) installed in a fluidic ejection system (Fig. 2,
208), according to an example of the principles described herein. Specifically, Fig. 3 depicts the fluidic ejection controller (100) in an assembled state. As can be seen in Fig 3, in some examples, the ejection board (104) is disposed between the firing board (102) and the fluidic ejection device (212). [0034] As described above, the ejection board (104) is modular to the firing board (102) and the fluidic ejection system (Fig 2, 208) as a whole. For example, screws or other connectors may mechanically fasten the ejection board (104) to the fluidic ejection system (Fig 2, 208). Electrical connectors on the ejection board (104) make contact with, or otherwise mate with,
corresponding electrical connectors on the firing board (102) such that electrical signals from the firing board (102) may be passed to the ejection board (104) where they may be tailored or otherwise manipulated to control the fluidic ejection device (212) that corresponds to the firing board (104).
[003S] Such a modular design allows for increased use of the fluidic ejection system (Fig. 2, 208) as the system is customizable to different fluidic ejection devices (212). That is, newly developed fluidic ejection devices (212) that may have different functionality or pad patterns, can be used by simply swapping out an old ejection board (104) for a different one to be used with the newly developed fluidic ejection device (212). Moreover, if electrical pins (106) become damaged, rather than replacing an entire firing circuitry, just the ejection board (104) may be replaced, thus reducing the cost of repair.
[0036] While Fig. 3 depicts a single fluidic ejection device (212) being received info the fluidic ejection controller (100), multiple fluidic ejection devices (212) may be inserted therein. For example, multiple fluidic ejection dies may be formed in a substrate and inserted into the fluidic ejection controller (100).
[0037] Fig. 4 is an exploded view of a fluidic ejection controller (100) with a removable ejection board (104) installed in a fluidic ejection system (Fig. 2,
208), according to an example of the principles described herein. Fig. 4 clearly depicts the electrical connectors (414) on the firing board (102) and the corresponding electrical connectors (416) on the ejection board (104) that are coupled together to route signals from the firing board (102) to the ejection board (104) where they are conditioned for the fluidic ejection device (212) that is inserted, and that is uniquely paired to interface with the ejection board (104).
[0038] Fig. 4 also clearly depicts the electrical pins (106) and the electrical pads (420) that interface with one another when the fluidic ejection device (212) is installed into the fluidic ejection controller (100). Via this electrical connection, the fluidic ejection die of the fluidic ejection device (212) is activated to eject a corresponding fluid. That is, through this connection, the fluidic ejection die of the fluidic ejection device (212) receives electrical signals directing when, where, and how to eject an amount of fluid therefrom. In an example, the fluidic ejection device (212) may be moved relative to a titration plate (Fig. 2, 210) and/or the titration plate (Fig 2, 210) may be moved relative to the fluidic ejection device (212) such that placement of the fluidic ejection die over any portion of the titration plate (Fig 2, 210) and ejection of fluid from the fluidic ejection die allows an amount of fluid to be ejected into any number of wells in the titration plate (Fig. 2, 210).
The ejection of the fluid from the fluidic ejection die is directed by a controller of the system as described above.
[0039] In some examples, the fluidic ejection controller (100) includes a guide mechanism (418) to align the fluidic ejection device (212) with the ejection board (104). For example, the guide mechanism (418) may have walls, and a portion of a floor that support, and guide, the fluidic ejection device (212) as it is slid into place.
[0040] Fig. 5 is a cross-sectional view of a fluid ejection device (212) prior to insertion into a fluidic ejection controller (Fig. 1 , 100) with a removable ejection board (104), according to an example of the principles described herein. In some examples, a fluidic ejection device (212) is positioned for fluidic ejection by sliding the fluidic ejection device (212) into electrical contact with the fluidic ejection controller (Fig. 1 , 100). For example, a user may grasp the fluidic ejection device (212), and slide it in a direction indicated by the arrow (522).
Note that in Fig. 5, the electrical pins (108) are not yet contacting the electrical pads (Fig. 4, 420).
[0041] Prior to installation, the electrical pins (106) are in an extended state. For example, the electrical pins (106) may be spring-loaded pins that are biased towards an extended position. However, when in contact with the leading edge of the fluidic ejection device (212), the electrical pins (106) retract into a housing in some examples, the leading edge of the fluidic ejection device (212) includes a bezel to deflect the electrical pins (106) into the housing upon insertion of the fluidic ejection device (212) into the fluidic ejection controller (Fig. 1 , 100). Without such a bezel, damage to the electrical pins (106) may occur as they come into contact with a vertical leading edge of the fluidic ejection device (212).
[0042] Fig. 6 is a cross-sectional view of a fluid ejection device (212) inserted into a fluidic ejection controller (Fig. 1 , 100) with a removable ejection board (104), according to an example of the principles described herein. As depicted in Fig. 6, the fluidic ejection device (212) is fully seated within the fluidic ejection controller (100). That is, the electrical pins (106), now in a retracted state, are aligned with the electrical pads (Fig. 4 420) of the fluidic ejection device (212). By providing manually aligned electrical pins (106) and electrical pads (Fig. 4, 420), the complexity of the fluidic ejection setup is reduced, as is the operation of the fluidic ejection system (Fig. 2, 208) as a whole. For example, rather than relying on motorized engagement features to align the electrical pins (106) with the electrical pads (Fig. 4, 420), alignment occurs as a user slides the fluidic ejection device (212) info place. Put another way, the fluidic ejection controller (Fig. 1 , 100) as described herein provides for a sliding-in motion of the fluidic ejection device (212) info the fluidic ejection controller (Fig. 1 , 100) to establish an electrical connection. This can eliminate the use a powered electrical engagement mechanism, which is prone to breaking down, is more complex to operate, and is more costly to manufacture.
[0043] Fig. 7 is an isometric view of a fluidic ejection device (212) aligned with a fluidic ejection controller (Fig. 1 , 100) with a removable ejection board (Fig. 1 , 104), according to an example of the principles described herein. Fig. 7 clearly depicts the electrical pins (106) in their retracted state, yet fully contacting the electrical pads (420). As described above, the electrical pins (106) may be biased towards an extended position such that there is downward force of the electrical pins (106) against the electrical pads (420) thus ensuring a solid electrical connection
[0044] In some examples, the fluidic ejection controller (Fig. 1 , 100) includes a connection indicator (724) which indicates a proper alignment of the fluidic ejection device (212) with the fiuidic ejection controller (Fig 1 , 100). As one specific example, the connection indicator (724) may be a light-emitting diode (LED) disposed on a housing of the fluidic ejection system (Fig. 2, 208) that turns a particular color, or turns on, or flashes, when there is an electrical connection between the electrical pins (106) and the electrical pads (420)
[0045] Fig 7 also clearly indicates the reservoir (726) which holds the fluid to be ejected. The reservoir (726) may be any void defined in the surface of the fluidic ejection device (212) that can hold an amount of fluid. The reservoir (726) provides the fluid to a die coupled to the substrate and may be on an opposite side of the fluidic ejection device (212) as the fiuidic ejection die. An example of a fluidic ejection die is depicted in Fig. 10. A slot may be formed between the reservoir (726) and the fluidic ejection die to direct the fluid towards the fiuidic ejection die using gravitational forces. In some examples, the reservoir (726) is exposed such that a user can deposit fluid therein.
[0046] Fig. 8 is a planar view of an ejection board (104) and a fiuidic ejection device (212), according to an example of the principles described herein.
Specifically, Fig. 8 depicts an underside view of the ejection board (104) with its corresponding electrical pins (106) that align with the electrical pads (420) and a top view of the fluidic ejection device (212) in some examples, the electrical pins (106) are disposed away from a leading edge of the fiuidic ejection controller (Fig. 1 , 100).
[0047] As described above, in some examples the ejection board (104) is unique to the particular fiuidic ejection device (212). More specifically, in some examples, the number and/or pattern of electrical pins (106) is unique to a particular fiuidic ejection device (212). As an example, the fluidic ejection device (212) of Fig. 8 has six electrical pads (420) in a particular pattern.
Accordingly, the ejection board (104) has the six electrical pins (106) arranged in the same pattern. By comparison, the fluidic ejection device (212) depicted in Fig. 9 has ten electrical pads (420) in a particular pattern. Accordingly, the corresponding ejection board (104) has ten electrical pins (106) in the same pattern. [0048] In some examples, the fluidic ejection device (212) includes a substrate into which a reservoir (726) is formed. The substrate may be any material, such as a monolithic thermoplastic material. In some examples, the thermoplastic material is doped with a non-conductive, metallic, inorganic compound. In this example, a metal traces may be added to any surface of the substrate using a laser direct structuring (LDS) process. During the LDS process, the non-conductive, metallic, inorganic compounds are activated by a laser providing a surface into which a layer of conduct metal may be deposited using, for example, an electroless copper bath.
[0049] The substrate may be formed to allow a user to insert or otherwise interface the fluidic ejection device (212) with a fluidic ejection system (Fig. 2, 208). In the example show in Fig. 8, the substrate may include a handle. The handle allows a user to grip the fluidic ejection device (212) in order to place the fluidic ejection device (212) into the fluidic ejection system (Fig. 2, 2008) The handle allows a user to touch, pick up, and move the fluidic ejection device (212) without contaminating the reservoir (726) or a fluid deposited therein.
[00S0] Fig. 9 is a top view of another ejection board (104) and a fluidic ejection device (212), according to an example of the principles described herein. As described above, the ejection board (104) and fluidic ejection device (212) have a different number, and pattern, of electrical pins (106) and electrical pads (420). The additional pins (106) and electrical pads (420) may provide additional or different functionality. For example, the additional electrical connections can facilitate a closed-look feedback function such as sensing of die temperature and sensing a property of the fluid. This additional functionality may not have been available when a previous fluidic ejection device (212) was released. While specific reference is made to particular additional functionalities provided by the additional pins (106) and pads (420), other functionalities may exist such as providing a static bar to remove a static charge from the fluid as it is deposited. [00S1] Fig. 10 is a bottom view of a fluidic ejection device (212), according to an example of the principles described herein. As described above, the reservoir (Fig. 7, 726) is fluidly coupled to a fluidic ejection die (1028) so that the fluid may be introduced to the fluidic ejection die (1028) for ejection into a number of the wells of the titration plate (Fig. 2, 210) as instructed by a fluidic ejection system (Fig. 2, 208).
[0052] T o eject the fluid, the fluidic ejection die (1026) includes an array of nozzles (1028). Each nozzle (1028) includes a number of components. For example, a nozzle (1028) includes an ejection chamber (1032) to hold an amount of fluid to be ejected, an opening (1030) through which the amount of fluid is ejected, and an actuator (1034), disposed within the ejection chamber (1032), to eject the amount of fluid through the opening (1030). It should be noted that the relative size of the nozzle openings (1030) and the fluidic ejection die (1028) are not to scale, with the nozzles (1028) being enlarged for purposes of illustration.
[0053] Turning to the actuators (1034), the actuator (1034) may include a firing resistor or other thermal device, a piezoelectric element, or other mechanism for ejecting fluid from the ejection chamber (1032). For example, the actuator (1034) may be a firing resistor. The firing resistor heats up in response to an applied voltage. As the firing resistor heats up, a portion of the fluid in the ejection chamber (1034) vaporizes to form a bubble. This bubble pushes fluid out the opening (1030) and onto the print medium. As the vaporized fluid bubble pops, fluid is drawn into the ejection chamber (1032) from a passage that connects nozzle (1028) to a fluid feed slot in the fluidic ejection die (1026), and the process repeats. In this example, the fluidic ejection die (1026) may be a thermal inkjet (TIJ) fluidic ejection die (1026).
[0054] in another example, the actuator (1034) may be a piezoelectric device. As a voltage is applied, the piezoelectric device changes shape which generates a pressure pulse in the ejection chamber (1032) that pushes the fluid out the opening (1030) and onto the print medium. In this example, the fluidic ejection die (1026) may be a piezoelectric inkjet (P!J) fluidic ejection die (1026). In addition to these components, the fluidic ejection die (1026) may include fluidic channels and chambers through which the fluid placed in the reservoir (Fig 7, 726) may flow through and out of the nozzles (1028).
[00SS] The fluidic ejection device (212) also includes electrical components on the front and back surfaces of the substrate. The electrical components may be made of any electrically conductive material to allow for electrical signals to be sent between the fluidic ejection system (Fig. 2, 208), via the electrical pins (Fig. 1 , 106) on the ejection board (Fig. 1 , 104) and the fluidic ejection die (1026). For example, contact pads (Fig. 4, 420) may be included on the front surface of the substrate. The contact pads (Fig. 4, 420) provide for an electrically conducive interface between the fluidic ejection system (Fig. 2, 208) and the fluidic ejection device (212).
[0056] Vias may be formed in the fluidic ejection device (212) and are electrically coupled to the contact pads (Fig. 4, 420). The vias may be any electrical connection that goes through the substrate and couples the
connection pads (Fig. 4, 420) to electrical components on the opposite side of the substrate.
[0057] The vias are coupled on the opposite side of the substrate to traces.
The traces may be coupled to the fluidic ejection die (1026) using wirebonds coupled between die pads of the fluidic ejection die (1026). In this manner, a fluidic ejection system (Fig. 2 208) via the firing board (Fig. 1, 102) and ejection board (Fig. 1, 104) may interface with the contact pads (Fig. 4, 420) defined on the front of the fluidic ejection device (212) in order to send electrical signals to the fluidic ejection die (1026) to cause the fluidic ejection die (1026) to, at least, eject an amount of fluid therefrom.
[0058] in summary, using such a fluidic ejection controller with a replaceable ejection board 1 ) is more robust in that it protects the electrical pins; 2) is more simple to operate based on a slide-in insertion motion which alleviates an electrical pin engagement mechanism such as a motor; 3) enables user- replacement of the electrical pin assembly on an ejection board without replacement of an entire firing board; 4) enables upgrade of the ejection board to an ejection board with a different number, or different arrangement, of electrical pins. The different quantity of electrical pins, when paired with corresponding electrical pads, can enable new functionality. However, it is contemplated that the devices disclosed herein may address other matters and deficiencies in a number of technical areas.
18

Claims

CLAIMS WHAT IS CLAIMED IS:
1. A fluidic ejection controller, comprising:
a firing board to pass electrical control signals for ejecting fluid from a fluidic ejection device;
an ejection board electrically coupled to, and selectively removable from, the firing board to pass the electrical control signals to the fluidic ejection device; and
electrical pins disposed on the ejection board in a pattern that matches a pattern of electrical pads on the fluidic ejection device;
wherein the electrical pins interface with corresponding electrical pads to pass the electrical control signals from the ejection board to the fluidic ejection device.
2. The fluidic ejection controller of claim 1 , wherein the electrical pins retract into a housing during insertion of the fluidic ejection device into the fluidic ejection controller.
3. The fluidic ejection controller of claim 1 , wherein the firing board is used to pass electrical control signals to a variety of fluidic ejection devices.
4. The fluidic ejection controller of claim 1 , wherein the ejection board is unique to a particular fluidic ejection device.
5. The fluidic ejection controller of claim 1 , wherein the pattern of the electrical pins is unique to a particular fluidic ejection device.
6. The fluidic ejection controller of claim 1 , wherein the ejection board is to receive multiple fluidic ejection devices simultaneously.
7. The fluidic ejection controller of claim 1 , further comprising a guide mechanism to align the fluidic ejection device with the ejection board during installation.
8. A fluidic ejection system comprising:
a fluidic ejection device comprising:
a reservoir disposed on a first side of a substrate;
a fluidic ejection die disposed on an opposite side of the substrate, wherein each fluidic ejection die comprises an array of nozzles, each nozzle comprising:
an ejection chamber;
an opening;
an actuator disposed within the ejection chamber; and an electrical pad to receive electrical control signals; and a fluidic ejection controller, comprising:
a firing board to pass electrical control signals for ejecting fluid from the fluidic ejection device;
an ejection board electrically coupled to, and selectively removable from, the firing board to pass the electrical control signals to the fluidic ejection device; and
an electrical pin disposed on the ejection board in a pattern that matches a pattern of the electrical pads on the fluidic ejection device.
9. The fluidic ejection system of claim 8, wherein the fluidic ejection device is slid into a housing of the fluidic ejection controller to align the electrical pins with the electrical pads
10. The fluidic ejection system of claim 8, further comprising a connection indicator which indicates a proper alignment of the fluidic ejection device with the fluidic ejection controller.
1 1 . The fluidic ejection system of claim 8, wherein the ejection board is modular to the fluidic ejection controller
12. The fluidic ejection system of claim 8, wherein the substrate comprises a bezel on a leading edge to deflect the electrical pins upon insertion of the fluidic ejection device into the fluidic ejection controller.
13. A fluidic ejection controller, comprising:
a firing board to pass electrical control signals for ejecting fluid from a fluidic ejection device;
an ejection board electrically coupled to, and selectively removable from, the firing board to pass the electrical control signals to the fluidic ejection device; and
electrical pins disposed on the ejection board in a pattern that matches a pattern of electrical pads on the fluidic ejection device, wherein:
the electrical pins interface with corresponding electrical pads to pass the electrical control signals from the ejection board to the fluidic ejection device;
the electrical pins are disposed in a pattern unique to a corresponding fluidic ejection device; and
the ejection board is unique to the corresponding fluidic ejection device.
14. The controller of claim 13, wherein the fluid is a biological fluid.
15. The controller of claim 13, wherein the electrical pins are disposed away from a leading edge of the fluidic ejection controller.
PCT/US2017/066612 2017-12-15 2017-12-15 Fluidic ejection controllers with selectively removable ejection boards WO2019117937A1 (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021002839A1 (en) 2019-07-01 2021-01-07 Hewlett-Packard Development Company, L.P. Fluid ejection controllers to pivotally hold firing boards

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019160528A2 (en) * 2018-01-30 2019-08-22 Hewlett-Packard Development Company, L.P. Fluid ejection devices with ionizers coupled to ejection head interfaces

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6536871B1 (en) * 1997-11-05 2003-03-25 Hewlett-Packard Company Reliable flex circuit interconnect on inkjet print cartridge
US6652057B2 (en) * 2001-01-31 2003-11-25 Canon Kabushiki Kaisha Printing apparatus
US20100053273A1 (en) * 2004-01-21 2010-03-04 Silverbrook Research Pty Ltd Printer Having Simple Connection Printhead
US20100073416A1 (en) * 2008-09-24 2010-03-25 Fujifilm Corporation Liquid droplet ejection control apparatus and liquid droplet ejecting apparatus
US8251471B2 (en) * 2003-08-18 2012-08-28 Fujifilm Dimatix, Inc. Individual jet voltage trimming circuitry
US8911044B2 (en) * 2011-01-04 2014-12-16 Toshiba Tec Kabushiki Kaisha Inkjet recording apparatus and recording method
US9333060B2 (en) * 2009-12-15 2016-05-10 Massachusetts Institute Of Technology Plaque removal and differentiation of tooth and gum

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4806106A (en) * 1987-04-09 1989-02-21 Hewlett-Packard Company Interconnect lead frame for thermal ink jet printhead and methods of manufacture
US5964239A (en) * 1996-05-23 1999-10-12 Hewlett-Packard Company Housing assembly for micromachined fluid handling structure
US6341845B1 (en) * 2000-08-25 2002-01-29 Hewlett-Packard Company Electrical connection for wide-array inkjet printhead assembly with hybrid carrier for printhead dies
US6705705B2 (en) * 1998-12-17 2004-03-16 Hewlett-Packard Development Company, L.P. Substrate for fluid ejection devices
US6273554B1 (en) * 2000-04-25 2001-08-14 Hewlett-Packard Company Apparatus for aligning a flexible circuit on a ink jet printer carriage
US6503454B1 (en) 2000-11-22 2003-01-07 Xerox Corporation Multi-ejector system for ejecting biofluids
US6431684B1 (en) * 2001-08-01 2002-08-13 Hewlett-Packard Company Spring pad for electrical interconnection of inkjet printing system
US8202491B2 (en) * 2006-11-21 2012-06-19 Bioscale, Inc. Apparatus for analyte processing
US9433939B2 (en) 2010-08-27 2016-09-06 Hewlett-Packard Development Company, L.P. Liquid dispensing assembly frame
CN103386816B (en) 2012-05-11 2016-01-20 科迪华公司 For the printhead unit assembly of ink-jet print system
US9274140B2 (en) 2013-02-20 2016-03-01 Silicon Laboratories Inc. Multi-purpose integrated circuit device contactor
US9415591B2 (en) 2014-03-06 2016-08-16 The Board Of Regents Of The University Of Texas System Apparatuses and methods for electrohydrodynamic printing
US11213818B2 (en) * 2015-11-25 2022-01-04 Spectradyne Llc Systems and devices for microfluidic instrumentation
JP6833425B2 (en) * 2016-09-23 2021-02-24 東芝テック株式会社 Droplet injection device
CN112041659A (en) * 2018-02-06 2020-12-04 瓦罗贝克两合公司 Microfluidic devices, systems, infrastructures, uses thereof, and methods for genetic engineering using same
US12070748B2 (en) * 2019-04-12 2024-08-27 Colorado State University Research Foundation Smart well device, multimodal system, and method for multi-analyte monitoring and processing
WO2021002839A1 (en) * 2019-07-01 2021-01-07 Hewlett-Packard Development Company, L.P. Fluid ejection controllers to pivotally hold firing boards
WO2021101850A1 (en) * 2019-11-18 2021-05-27 Deepdivebio, Inc. Thermocycler temperature control
US20220297122A1 (en) * 2021-03-17 2022-09-22 Cytonome/St, Llc Microfluidic assembly for surface acoustic wave particle manipulation

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6536871B1 (en) * 1997-11-05 2003-03-25 Hewlett-Packard Company Reliable flex circuit interconnect on inkjet print cartridge
US6652057B2 (en) * 2001-01-31 2003-11-25 Canon Kabushiki Kaisha Printing apparatus
US8251471B2 (en) * 2003-08-18 2012-08-28 Fujifilm Dimatix, Inc. Individual jet voltage trimming circuitry
US20100053273A1 (en) * 2004-01-21 2010-03-04 Silverbrook Research Pty Ltd Printer Having Simple Connection Printhead
US20100073416A1 (en) * 2008-09-24 2010-03-25 Fujifilm Corporation Liquid droplet ejection control apparatus and liquid droplet ejecting apparatus
US9333060B2 (en) * 2009-12-15 2016-05-10 Massachusetts Institute Of Technology Plaque removal and differentiation of tooth and gum
US8911044B2 (en) * 2011-01-04 2014-12-16 Toshiba Tec Kabushiki Kaisha Inkjet recording apparatus and recording method

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021002839A1 (en) 2019-07-01 2021-01-07 Hewlett-Packard Development Company, L.P. Fluid ejection controllers to pivotally hold firing boards
US11975547B2 (en) 2019-07-01 2024-05-07 Hewlett-Packard Development Company, L.P. Fluid ejection controllers to pivotally hold firing boards

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