WO2019005973A1 - Synthetase variants for incorporation of biphenylalanine into a peptide - Google Patents

Synthetase variants for incorporation of biphenylalanine into a peptide Download PDF

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Publication number
WO2019005973A1
WO2019005973A1 PCT/US2018/039764 US2018039764W WO2019005973A1 WO 2019005973 A1 WO2019005973 A1 WO 2019005973A1 US 2018039764 W US2018039764 W US 2018039764W WO 2019005973 A1 WO2019005973 A1 WO 2019005973A1
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WO
WIPO (PCT)
Prior art keywords
variant
amino acid
trna
amino
trna synthetase
Prior art date
Application number
PCT/US2018/039764
Other languages
French (fr)
Inventor
Aditya Mohan KUNJAPUR
George M. Church
Devon Alexander Olson STORK
Erkin KURU
Original Assignee
President And Fellows Of Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US201762527115P priority Critical
Priority to US62/527,115 priority
Application filed by President And Fellows Of Harvard College filed Critical President And Fellows Of Harvard College
Publication of WO2019005973A1 publication Critical patent/WO2019005973A1/en

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