WO2018180392A1 - 呼吸情報取得装置および呼吸情報取得方法 - Google Patents
呼吸情報取得装置および呼吸情報取得方法 Download PDFInfo
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- WO2018180392A1 WO2018180392A1 PCT/JP2018/009378 JP2018009378W WO2018180392A1 WO 2018180392 A1 WO2018180392 A1 WO 2018180392A1 JP 2018009378 W JP2018009378 W JP 2018009378W WO 2018180392 A1 WO2018180392 A1 WO 2018180392A1
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/021—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes operated by electrical means
- A61M16/022—Control means therefor
- A61M16/024—Control means therefor including calculation means, e.g. using a processor
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
- A61M16/1005—Preparation of respiratory gases or vapours with O2 features or with parameter measurement
- A61M16/101—Preparation of respiratory gases or vapours with O2 features or with parameter measurement using an oxygen concentrator
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/20—Valves specially adapted to medical respiratory devices
- A61M16/201—Controlled valves
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/06—Respiratory or anaesthetic masks
- A61M16/0666—Nasal cannulas or tubing
- A61M16/0672—Nasal cannula assemblies for oxygen therapy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
- A61M16/14—Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase
- A61M16/16—Devices to humidify the respiration air
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/20—Valves specially adapted to medical respiratory devices
- A61M16/201—Controlled valves
- A61M16/202—Controlled valves electrically actuated
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- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
- A61M2016/0027—Accessories therefor, e.g. sensors, vibrators, negative pressure pressure meter
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- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/0007—Special media to be introduced, removed or treated introduced into the body
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- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/02—Gases
- A61M2202/0208—Oxygen
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- A—HUMAN NECESSITIES
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- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
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- A61M2205/00—General characteristics of the apparatus
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- A61M2205/00—General characteristics of the apparatus
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- A—HUMAN NECESSITIES
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- A61M2205/00—General characteristics of the apparatus
- A61M2205/50—General characteristics of the apparatus with microprocessors or computers
- A61M2205/52—General characteristics of the apparatus with microprocessors or computers with memories providing a history of measured variating parameters of apparatus or patient
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
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- A—HUMAN NECESSITIES
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- A61M2230/00—Measuring parameters of the user
- A61M2230/40—Respiratory characteristics
- A61M2230/43—Composition of exhalation
- A61M2230/435—Composition of exhalation partial O2 pressure (P-O2)
Definitions
- the present invention relates to a respiratory information acquisition device and a respiratory information acquisition method used for a PSA oxygen concentrator.
- oxygen therapy has been performed as one of the patients with respiratory diseases such as asthma and obstructive chronic lung disease. This is a therapy that allows a patient to inhale oxygen gas or oxygen-enriched gas.
- home oxygen therapy HET: Oxygen® Therapy
- oxygen concentrators are mainly used as oxygen supply sources. Yes.
- An oxygen concentrator is an apparatus that concentrates and discharges about 21% of oxygen present in the air.
- Many of the oxygen concentrators generally use a pressure fluctuation adsorption type (hereinafter referred to as PSA type: Pressure Swing Adsorption) (hereinafter, the PSA type oxygen concentrator is simply referred to as an oxygen concentrator).
- PSA type oxygen concentrator air is taken into a cylinder filled with an adsorbent that selectively adsorbs nitrogen gas, and concentrated oxygen gas is generated by repeating pressurization and depressurization. With this mechanism, the oxygen concentrator can continuously provide high-concentration oxygen gas to the patient.
- COPD chronic obstructive pulmonary disease
- COPD chronic Obstructive Pulmonary Disease
- the patient's respiratory information can be acquired inside the oxygen concentrator during operation of the oxygen concentrator, the patient's breathing information can be acquired without changing the feeling of use compared to the conventional general oxygen concentrator. This is a very useful means because it is possible to confirm that the patient is connected by an oxygen supply tube and the actual usage of the patient.
- Japanese Patent Laid-Open No. 6-190045 JP 2001-286666 A Japanese Patent Laid-Open No. 7-96035 Japanese Patent Laying-Open No. 2015-85191 Special table 2011-518016 gazette
- Patent Document 1 and Patent Document 2 As a method for acquiring respiratory information of a patient while the oxygen concentrator is in operation, as shown in Patent Document 1 and Patent Document 2, a breath measuring micrometer is used between the oxygen concentrator and the cannula worn by the patient. There is a method for measuring a patient's respiratory pressure during oxygen inhalation by attaching a differential pressure sensor.
- the pressure fluctuation added to the differential pressure measurement system includes the pressure fluctuation accompanying the pressure increase / decrease during the generation of the concentrated oxygen gas.
- the oxygen concentrator is a PSA operation method, and the supply oxygen flow rate fluctuates accordingly. Therefore, pressure fluctuations associated with PSA always occur in the oxygen supply path.
- Patent Documents 3 and 4 there is a method of obtaining patient respiratory information by measuring the patient respiratory pressure during oxygen inhalation with a slight differential pressure sensor and then processing the obtained respiratory pressure data softly.
- these conventional techniques do not consider pressure fluctuations associated with PSA superimposed on patient respiratory pressure, it is impossible to accurately acquire patient respiratory information.
- Patent Document 5 describes a method of obtaining respiratory information by frequency analysis of the obtained respiratory pressure data.
- frequency analysis there is a drawback that it is difficult to separate a respiratory component and a pressure fluctuation component accompanying PSA, and accuracy is poor.
- the present inventor has arrived at the present invention as a result of earnest research to solve the above-mentioned problems in the method of acquiring the respiratory information of the patient during the operation of the conventional oxygen concentrator.
- the present invention relates to a respiratory information acquisition device used in a PSA oxygen concentrator that switches between a plurality of adsorption cylinders, and in the oxygen supply path in a state where oxygen is supplied to the patient from the PSA oxygen concentrator.
- Respiration information for measuring a first pressure that is a periodic pressure fluctuation and a second pressure that is a periodic pressure fluctuation in the oxygen supply path in a state where oxygen is not supplied to the patient from the PSA oxygen concentrator.
- Difference processing for calculating a difference between the first pressure and the second pressure in a state in which the acquisition means, the phase confirmation means for matching the phases of the first pressure and the second pressure, and the phases are matched.
- a breathing information acquisition device used in a PSA oxygen concentrator that switches between a plurality of adsorption cylinders, and in the oxygen supply path in a state where oxygen is supplied to the patient from the PSA oxygen concentrator.
- the phase confirmation unit may be a unit that calculates data for one cycle of the pressure fluctuation of the first pressure and data for one cycle of the pressure fluctuation of the second pressure to match the phases.
- the phase confirmation unit may be a unit that detects a peak pressure of the first pressure and the second pressure and matches a phase of the peak pressure.
- a switching valve for permitting or blocking oxygen supply from the PSA type oxygen concentrator to the patient may be provided in the oxygen supply path.
- the breathing information acquisition means may include a slight differential pressure sensor, and measure the differential pressure at both ends of an arbitrary point in the oxygen supply path and a constant pressure.
- the present invention also provides a first pressure that is a periodic pressure fluctuation in an oxygen supply path in a state where oxygen is supplied to a patient from a PSA oxygen concentrator that switches between a plurality of adsorption cylinders, and the PSA type
- a breathing information acquisition process for measuring a second pressure that is a periodic pressure fluctuation in the oxygen supply path in a state where oxygen is not supplied to the patient from the oxygen concentrator, the first pressure, and the second pressure
- a breathing information acquisition method comprising: a phase confirmation process for matching the phases of the first and second processes for calculating a difference between the first pressure and the second pressure in a state where the phases are matched.
- patient respiratory information can be obtained by separating the patient respiratory component and the pressure fluctuation component associated with PSA during operation of the oxygen concentrator.
- FIG. It is a figure which shows the structure of the oxygen concentration apparatus which concerns on Embodiment 1.
- FIG. It is a figure which shows the form which acquires the respiratory information of the patient which concerns on Embodiment 1.
- FIG. It is a figure which shows the pressure data containing patient respiration information in the conditions which added 10m of continuous flow 1LPM and extension tubes.
- FIG. It is a figure which shows the PSA pressure data recorded beforehand on the conditions which added 10 m of continuous flow 1LPM and extension tubes.
- the PSA type oxygen concentrator 1 includes an oxygen generator 11 that takes in air from the outside of the PSA type oxygen concentrator 1 and generates concentrated oxygen gas.
- the air taken into the oxygen generator 11 from the outside of the oxygen generator is compressed by the compressor 111 and sent to the cylinder 113 via the first switching valve 112.
- the first switching valve 112 communicates one of the plurality of cylinders 113 with the compressor 111 to send compressed air to the cylinder 113 and open the other cylinders to the atmosphere.
- the cylinder 113 is filled with an adsorbent that selectively adsorbs nitrogen gas.
- the compressed air that has passed through the cylinder 113 has a reduced nitrogen gas concentration and becomes a concentrated oxygen gas.
- the concentrated oxygen gas is stored in the concentrated oxygen buffer tank 115 via the second switching valve 114.
- the second switching valve 114 communicates or blocks any one of the plurality of cylinders 113 and the concentrated oxygen buffer tank 115.
- the oxygen generator 11 causes the compressor 111 and any of the plurality of cylinders 113 to communicate with each other by the first switching valve 112, and causes the cylinder 113 and the concentrated oxygen buffer tank 115 to communicate with the compressor 111 by the second switching valve 114. . Therefore, the compressor 111 and any one of the plurality of cylinders 113 are connected to the concentrated oxygen buffer tank 115, and the generated concentrated oxygen gas is supplied to the concentrated oxygen buffer tank 115. On the other hand, the cylinder 113 that does not communicate with the compressor 111 is opened to the atmosphere via the first switching valve 112 while being blocked from the concentrated oxygen buffer tank 115 by the second switching valve 114. Thereby, the inside of the cylinder 113 is depressurized, and the nitrogen gas adsorbed by the adsorbent is released to the outside of the oxygen concentrator.
- the first switching valve 112 shuts off the compressor 111 and releases it to the atmosphere.
- the cylinder 113 that has been released to the atmosphere is connected to the compressor 111 by the first switching valve 112 and moves to the process of oxygen compression. In this way, the plurality of cylinders 113 alternately repeat compression and release to the atmosphere by the first switching valve 112, so that the concentrated oxygen gas can be continuously supplied.
- the oxygen flow rate of the concentrated oxygen gas whose pressure has been adjusted by the oxygen generation unit 11 is controlled by an oxygen flow rate control unit 12 including a control valve 121 and a flow meter 122, and is supplied from the oxygen supply port 13 to the outside of the oxygen concentrator via the humidifier 101.
- an oxygen flow rate control unit 12 including a control valve 121 and a flow meter 122, and is supplied from the oxygen supply port 13 to the outside of the oxygen concentrator via the humidifier 101.
- the control valve 121 or the flow meter 122 may be provided upstream of the flow path, and the oxygen flow control unit 12 may include other configurations.
- the oxygen concentrator 1 may be configured without the humidifier 101.
- FIG. 2 schematically shows an example of an embodiment of the present invention, which is an example of a form for acquiring patient respiratory information.
- the oxygen generated by the oxygen concentration device 1 is supplied to the patient via the extension tube 2 and the nasal cannula 3.
- the patient constantly breathes even during oxygen inhalation, and the pressure change caused by the patient's breathing is propagated toward the nasal cannula 3, the extension tube 2, and the oxygen concentrator 1.
- the respiratory information acquisition means 4 in order to acquire a patient's respiratory pressure, is connected in an oxygen supply path.
- FIG. 2 the case where the respiration information acquisition means 4 is connected to an extension tube is shown as an example.
- the respiration information acquisition unit 4 may be connected between the humidifier 101 (or the oxygen flow rate control unit 12 when the oxygen concentrator 1 does not include the humidifier 101) and the nasal cannula 3.
- the respiratory information acquisition means 4 may be installed inside the oxygen concentrator 1 or may be installed outside the oxygen concentrator 1 separately from the oxygen concentrator 1.
- the pressure fluctuation applied to the breathing information acquisition means 4 is accompanied by the pressure increase / decrease at the time of the generation of concentrated oxygen gas. It became clear that pressure fluctuation was included.
- the amplitude of the pressure fluctuation that occurs during the generation of the concentrated oxygen gas is larger than the amplitude of the respiratory pressure, and the amplitude of the respiratory pressure also decreases due to the pressure loss caused by passing through the oxygen flow path. It is difficult to measure the respiratory pressure waveform of a patient directly from
- the respiratory information acquisition unit 4 includes an orifice 5, a slight differential pressure sensor 6, and a control unit 7.
- One end of the slightly differential pressure sensor 6 is connected to a branch point in the oxygen supply path provided in the extension tube 2. That is, the pressure in the oxygen supply path including both the pressure fluctuation accompanying the pressure increase / decrease when the concentrated oxygen gas is generated and the breathing pressure of the patient is directly input to one end of the fine differential pressure sensor 6.
- An air communication path that communicates with the atmosphere is provided between the minute differential pressure sensor 6 and the branch point of the oxygen supply path, and a third switching valve 8 is provided in the air communication path.
- the third switching valve 8 is a variable flow valve, and the pressure supplied to the fine differential pressure sensor 6 is adjusted by adjusting the flow rate.
- the other end of the slightly differential pressure sensor 6 is connected to the oxygen supply path via the orifice 5. Since the respiratory pressure of the patient is usually about ⁇ 10 to 100 Pa, in order to acquire the respiratory pressure by the respiratory information acquisition means 4, it is preferable to use a sensor having a range of about ⁇ 100 Pa for the fine differential pressure sensor 6. In a situation where oxygen is supplied from the oxygen concentrator, a supply pressure due to oxygen supply always occurs, and this is about 300 Pa even at 1 LPM. Therefore, if one end of the fine differential pressure sensor 6 is connected to the oxygen supply path in the state where the other end of the fine differential pressure sensor 6 is released to the atmosphere, the range of the fine differential pressure sensor 6 will be exceeded. Therefore, it is preferable to obtain the pressure including the respiratory information of the patient within the range of the fine differential pressure sensor 6 by applying the pressure after passing through the orifice 5 to the other end of the fine differential pressure sensor 6.
- a control unit 7 is connected to the slightly differential pressure sensor 6.
- the control unit 7 includes an input / output interface, a first memory, a second memory, and a CPU (Central Processing Unit).
- the control unit 7 receives and records the pressure including the patient respiration information detected by the fine differential pressure sensor 6, and acquires the patient respiration information by executing the processing described below.
- the first memory and the second memory may be separate memories, or a single memory may be virtually divided.
- a fourth switching valve 9 is provided on the downstream side of the extension tube 2 from the branch point of the oxygen supply path.
- the fourth switching valve is a shut-off valve, which permits or blocks oxygen supply to the nasal cannula 3.
- Embodiment 1 uses the data obtained by applying the respiratory pressure of the patient respiratory model (expiratory pressure: 30 Pa, inspiratory pressure: ⁇ 50 Pa, BPM 20 times) from the nasal cannula 3 using the configuration shown in FIG. 2 and acquiring respiratory information. The principle of the process carried out in will be described.
- FIG. 3 shows the pressure data including the respiratory information of the patient and the PSA pressure data of the oxygen concentrator, and during the period from 0 to about 15 seconds from the start of measurement, the oxygen concentrator is not applied without applying the patient respiratory pressure. It is data of a time zone in which only the PSA pressure is measured.
- FIG. 4 shows the PSA pressure data of the oxygen concentrator previously acquired and recorded in the storage medium.
- the PSA pressure by the oxygen concentrator is a periodic pressure change accompanying the adsorption cylinder cycle of the PSA oxygen concentrator generated when oxygen is generated by the PSA oxygen concentrator described above. Therefore, the cycle of the PSA pressure waveform coincides with the adsorption cylinder switching cycle of the oxygen concentrator.
- the amplitude of the PSA pressure is about 20 Pa.
- the patient respiratory pressure is superimposed on the PSA pressure.
- the respiratory pressure of the patient respiratory model is PSA. It is drowned out by pressure and cannot be observed. Accordingly, the inventors of the present application have made extensive studies and devised a method of removing only the PSA pressure component by subtracting the component of FIG. 4 from the component of FIG. 3 on the software in order to obtain the respiratory pressure of the patient respiratory model.
- FIG. 5 shows the result of the difference processing performed by software in a state where both phases are in alignment.
- the difference process is a process for calculating a difference between both data at an arbitrary time.
- the breathing pressure of the patient breathing model is not applied for the time from 0 to about 15 seconds and the oxygen concentrator is in operation, no characteristic waveform is seen.
- a periodic pressure fluctuation with an amplitude of about 20 Pa can be observed. That is, the respiratory pressure of the patient respiratory model can be detected.
- the soft difference process it is possible to obtain the respiratory information of the patient even in a situation where oxygen is continuously inhaled from the oxygen concentrator through the nasal cannula and the extension tube 10m.
- FIG. 6 shows the pressure data including the patient respiratory information and the PSA pressure data of the oxygen concentrator as in FIG. 3, and the patient respiratory pressure is not applied during the period of 0 to about 10 seconds from the start of the measurement.
- it is data of a time zone in which only the PSA pressure of the oxygen concentrator is measured.
- FIG. 7 shows the PSA pressure data of the oxygen concentrator previously acquired and recorded in the storage medium.
- the shape of the waveform changes compared to FIGS. 7 and 4 because the driving cycle for adsorbing and desorbing nitrogen with the adsorbent when producing concentrated oxygen differs for each oxygen supply flow rate produced. is there.
- FIG. 6 shows the respiratory pressure of the patient respiratory model in the state where the phases of both data are matched. Similar to FIG. 5, a pressure fluctuation with an amplitude of about 20 Pa that can be observed periodically from about 10 seconds after the start of measurement when respiratory pressure is applied can be observed. That is, the respiratory pressure of the patient respiratory model can be detected.
- step S1 when the oxygen concentrator 1 is turned on, the oxygen concentrator 1 starts operation and starts supplying concentrated oxygen gas.
- the control unit 7 receives the measurement value of the differential pressure sensor 6 which is pressure data in the oxygen supply path, and starts recording. Further, the control unit 7 starts counting time from the start of measurement (power ON) and proceeds to step S2.
- PSA pressure data not including patient respiratory information corresponding to the data shown in FIGS. 4 and 7 is acquired from the pressure in the oxygen supply path.
- step S2 it is determined whether or not a predetermined time has elapsed after measurement of pressure data in the oxygen supply path in step S1 is started.
- the predetermined time is set to such a length that pressure data for at least one PSA pressure cycle can be acquired.
- the breathing cycle of the patient is usually about 3 seconds and at most about 6 seconds.
- the measurement data for one cycle of the PSA pressure includes at least one cycle of patient respiration information.
- the PSA pressure cycle is less than 6 seconds, the measurement data for one cycle of the PSA pressure does not include patient respiration information for one cycle or more, so the predetermined time is preferably 6 seconds or more.
- step S2 If it is determined in step S2 that the predetermined time has not elapsed, the process proceeds to step S3, where the fourth switching valve 9 is closed and the third switching valve 8 is opened.
- the opening degree of the third switching valve 8 is a predetermined opening degree corresponding to the pressure loss of the extension tube 2 and the nasal cannula 3.
- the predetermined opening may be selected from a plurality of predetermined opening according to the length of the extension tube.
- step S4 the pressure data in the oxygen supply path is stored in the first memory and the second memory of the control unit 7.
- data acquisition may be started after a certain time, for example, 0.1 seconds or more has elapsed since the start of measurement.
- the control unit 7 repeats the processes of Step S3 and Step S4 until a predetermined time has elapsed after starting measurement of pressure data in the oxygen supply path. That is, PSA pressure data not including patient respiratory information is recorded in the first memory and the second memory for a period including pressure data for at least one PSA pressure cycle.
- step S2 If it is determined in step S2 that the predetermined time has elapsed, the process proceeds to step S5, the third switching valve 8 is closed, and the fourth switching valve 9 is completely opened. Thereby, the oxygen supply to a patient is started. Thereafter, the measurement value of the fine differential pressure sensor 6 includes the respiratory information of the patient. Thereafter, in step S6, pressure data related to the oxygen supply path is stored in the first memory.
- step S7 prior to the difference process in step S8, the phase between the data stored in the first memory and the data stored in the second memory is confirmed, and if necessary, a phase confirmation process for matching the phases is performed. .
- the state in which the two data are in phase is a state in which the time data components indicating the pressure peaks (maximum values) of the two data measured by the control unit 7 match.
- a method of matching the phases a method of aligning the PSA pressure peak values of both data or a time differentiation of the pressure waveforms of both data to align the time data components at a point where the time change of the measured pressure is large. There are methods.
- the control unit 7 extracts data from the data stored in the first memory every one PSA pressure cycle. Specifically, since the time interval between the peak (maximum value) of the pressure data stored in the first memory and the next peak corresponds to one cycle of the PSA pressure cycle, the data stored in the first memory Each peak is detected, the time interval between the peak and the next peak is obtained, and data is taken out at each time interval between the peak and the next peak. Note that, as described above, since data having a certain period of time since the start of measurement has higher reliability, data until a certain period of time has elapsed from the start of measurement may not be used. The same applies to the data stored in the second memory. On the other hand, the control unit 7 extracts PSA pressure cycle data, which is data for one PSA pressure cycle, from the data stored in the second memory by the same method.
- step S8 the PSA pressure cycle extracted from the data stored in the first memory and the data stored in the second memory extracted every one PSA pressure cycle whose phases are matched in step S7 Difference processing with data is performed. Thereby, data having patient respiration information for one cycle of the PSA pressure cycle is obtained.
- the phase confirmation process and the difference process need not be executed with a data length corresponding to one PSA pressure cycle, and data is extracted every predetermined number of PSA pressure cycles from the data stored in the first memory.
- the PSA pressure measurement data extracted from the data stored in the second memory can be generated by connecting the PSA pressure measurement data for a predetermined number of cycles, and the PSA pressure data used for the differential processing can be generated using both data.
- step S9 the data having the patient respiration information acquired in step S8 is analyzed to acquire patient respiration information, for example, respiration strength and respiration frequency. Furthermore, if data having patient respiration information for one cycle of each PSA pressure cycle is connected, data having patient respiration information for the entire period from the power-on can be obtained, and using this, average data can be obtained. The intensity of breathing and the number of breaths within the usage time can be acquired.
- step S10 it is determined whether or not the oxygen concentrator is turned off. In step S10, when it is not determined that the oxygen concentrator is turned off, the process returns to step S5, and the processes from step S6 to step S9 are repeated. If it is determined in step S10 that the power source of the oxygen concentrator is turned off, the flowchart ends.
- the patient respiratory information can be obtained by separating the patient respiratory component and the pressure fluctuation component associated with the PSA from the data obtained by measuring the patient respiratory pressure during operation of the oxygen concentrator. it can.
- oxygen concentrator 11 oxygen generator 12: oxygen flow rate adjuster 13: oxygen supply port 111: compressor 112: switching valve 113: cylinder 114: switching valve 115: concentrated oxygen buffer tank 116: pressure regulating valve 121: control valve 122 : Flow meter 101: Humidifier 2: Extension tube 3: Nasal cannula 4: Respiration information acquisition means 5: Orifice 6: Slight differential pressure sensor 7: Controller 8: Third switching valve 9: Fourth switching valve
Abstract
Description
PSA式酸素濃縮装置では、窒素ガスを選択的に吸着する吸着剤が充填されたシリンダーに空気を取り込み、加減圧を繰り返すことで濃縮酸素ガスを生成する。この仕組みによって、酸素濃縮装置は患者に連続的に高濃度酸素ガスを提供することができる。
前記位相確認手段は、前記第1圧力と前記第2圧力のピーク圧を検出し、ピーク圧の位相を合わせる手段であってもよい。
前記酸素供給経路内に、前記PSA式酸素濃縮装置から前記患者への酸素供給を許可または遮断する切替弁を備えていてもよい。
前記呼吸情報取得手段は微差圧センサを備え、前記酸素供給経路内の任意点と一定圧との両端で差圧を計測してもよい。
図1を用いて本実施形態に関わるPSA式酸素濃縮装置の構成を説明する。
図2に示す構成を用いて鼻カニューラ3から患者呼吸モデルの呼吸圧(呼気圧:30Pa、吸気圧:-50Pa、BPM20回)を印加し、呼吸情報を取得したデータを用いて、本実施形態で行われる処理の原理について説明する。
ステップS1において、酸素濃縮装置1の電源をONにすると、酸素濃縮装置1は運転を開始し濃縮酸素ガスの供給を開始する。同時に、制御部7は、酸素供給経路内の圧データである差圧センサ6の計測値を受け取って記録を開始する。さらに、制御部7は計測開始(電源ON)からの時間のカウントを開始してステップS2に進む。本実施形態においては、酸素供給経路内の圧から、図4および図7に示したデータに相当する患者呼吸情報を含まないPSA圧データを取得する。具体的には、ステップS2において、ステップS1における酸素供給経路内に係る圧データの計測を開始した後、所定時間が経過したか否かを判断する。所定時間は、少なくともPSA圧周期の1周期分の圧データを取得することが可能な程度の長さで設定される。ここで、患者の呼吸周期は通常3秒程度、長くても6秒程度である。PSA圧周期が6秒以上の場合は、PSA圧の1周期分の測定データには少なくとも1周期分以上の患者呼吸情報が含まれる。一方、PSA圧周期が6秒未満の場合は、PSA圧の1周期分の測定データに1周期分以上の患者呼吸情報が含まれないため、所定時間は6秒以上が好ましい。
その後、ステップS6において酸素供給経路内に係る圧データを第1メモリに格納する。
ステップS10において、酸素濃縮装置の電源がOFFと判断された場合は、該フローチャートを終了する。
11:酸素生成部
12:酸素流量調整部
13:酸素供給口
111:コンプレッサー
112:切替弁
113:シリンダー
114:切替弁
115:濃縮酸素バッファタンク
116:調圧弁
121:コントロールバルブ
122:流量計
101:加湿器
2:延長チューブ
3:鼻カニューレ
4:呼吸情報取得手段
5:オリフィス
6:微差圧センサ
7:制御部
8:第3切替弁
9:第4切替弁
Claims (6)
- 複数の吸着筒を切り替えて使用するPSA式酸素濃縮装置に用いられる呼吸情報取得装置において、
前記PSA式酸素濃縮装置から患者に酸素が供給されている状態の酸素供給経路内の周期的な圧変動である第1圧力と、前記PSA式酸素濃縮装置から患者に酸素が供給されない状態の前記酸素供給経路内の周期的な圧変動である第2圧力と、を計測する呼吸情報取得手段と、
前記第1圧力と前記第2圧力と、の位相を合わせる位相確認手段と、
前記位相を合わせた状態で、前記第1圧力と前記第2圧力と、の差分を算出する差分処理手段と、
を備えた呼吸情報取得装置。 - 前記位相確認手段は、前記第1圧力の圧変動の1周期分のデータと前記第2圧力の圧変動の1周期分のデータと、を算出して位相を合わせる手段である、呼吸情報取得装置。
- 前記位相確認手段は、前記第1圧力と前記第2圧力のピーク圧を検出し、ピーク圧の位相を合わせる手段である、請求項1または2に記載の呼吸情報取得装置。
- 前記酸素供給経路内に、前記PSA式酸素濃縮装置から前記患者への酸素供給を許可または遮断する切替弁を備える、請求項1から3のいずれかに記載の呼吸情報取得装置。
- 前記呼吸情報取得手段は微差圧センサを備え、前記酸素供給経路内の任意点と一定圧との両端で差圧を計測する、請求項1から4のいずれかに記載の呼吸情報取得装置。
- 複数の吸着筒を切り替えて使用するPSA式酸素濃縮装置から患者に酸素が供給されている状態の酸素供給経路内の周期的な圧変動である第1圧力と、前記PSA式酸素濃縮装置から患者に酸素が供給されない状態の前記酸素供給経路内の周期的な圧変動である第2圧力と、を計測する呼吸情報取得処理と、
前記第1圧力と前記第2圧力と、の位相を合わせる位相確認処理と、
前記位相を合わせた状態で、前記第1圧力と前記第2圧力と、の差分を算出する差分処理と、
を備えた呼吸情報取得方法。
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