WO2018119253A1 - Modulation of enzymatic polynucleotide synthesis using chelated divalent cations - Google Patents

Modulation of enzymatic polynucleotide synthesis using chelated divalent cations Download PDF

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Publication number
WO2018119253A1
WO2018119253A1 PCT/US2017/067931 US2017067931W WO2018119253A1 WO 2018119253 A1 WO2018119253 A1 WO 2018119253A1 US 2017067931 W US2017067931 W US 2017067931W WO 2018119253 A1 WO2018119253 A1 WO 2018119253A1
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WO
WIPO (PCT)
Prior art keywords
reaction
method
nucleotide
template
chelating agent
Prior art date
Application number
PCT/US2017/067931
Other languages
French (fr)
Inventor
Kettner John Frederick GRISWOLD, Jr.
Howon Lee
George M. Church
Original Assignee
President And Fellows Of Harvard College
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Publication date
Priority to US201662437349P priority Critical
Priority to US62/437,349 priority
Application filed by President And Fellows Of Harvard College filed Critical President And Fellows Of Harvard College
Publication of WO2018119253A1 publication Critical patent/WO2018119253A1/en

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