WO2017155945A1 - Methods and systems of cell-free enzyme discovery and optimization - Google Patents

Methods and systems of cell-free enzyme discovery and optimization Download PDF

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Publication number
WO2017155945A1
WO2017155945A1 PCT/US2017/021087 US2017021087W WO2017155945A1 WO 2017155945 A1 WO2017155945 A1 WO 2017155945A1 US 2017021087 W US2017021087 W US 2017021087W WO 2017155945 A1 WO2017155945 A1 WO 2017155945A1
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WO
WIPO (PCT)
Prior art keywords
reporter
metabolite
enzyme
sensor biomolecule
variant
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PCT/US2017/021087
Other languages
French (fr)
Inventor
George M. Church
Jameson K. Rogers
Marc Guell
Alexander GARRUSS
Original Assignee
President And Fellows Of Harvard College
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Publication date
Priority to US201662305586P priority Critical
Priority to US62/305,586 priority
Application filed by President And Fellows Of Harvard College filed Critical President And Fellows Of Harvard College
Publication of WO2017155945A1 publication Critical patent/WO2017155945A1/en

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