WO2017060750A1 - Use of a withania extract for the treatment of demyelinating deseases - Google Patents

Use of a withania extract for the treatment of demyelinating deseases

Info

Publication number
WO2017060750A1
WO2017060750A1 PCT/IB2015/001979 IB2015001979W WO2017060750A1 WO 2017060750 A1 WO2017060750 A1 WO 2017060750A1 IB 2015001979 W IB2015001979 W IB 2015001979W WO 2017060750 A1 WO2017060750 A1 WO 2017060750A1
Authority
WO
Grant status
Application
Patent type
Prior art keywords
ms
decrease
composition
extract
composition according
Prior art date
Application number
PCT/IB2015/001979
Other languages
English (en)
French (fr)
Inventor
Chérif RABHI
Léon Cariel
Jamal Ouazzani
Guillaume ARCILE
Original Assignee
Ethnodyne
Centre National De La Recherche Scientifique (Cnrs)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/062Ascomycota
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/67Piperaceae (Pepper family), e.g. Jamaican pepper or kava
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9066Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
PCT/IB2015/001979 2015-10-05 2015-10-05 Use of a withania extract for the treatment of demyelinating deseases WO2017060750A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/IB2015/001979 WO2017060750A1 (en) 2015-10-05 2015-10-05 Use of a withania extract for the treatment of demyelinating deseases

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IB2015/001979 WO2017060750A1 (en) 2015-10-05 2015-10-05 Use of a withania extract for the treatment of demyelinating deseases

Publications (1)

Publication Number Publication Date
WO2017060750A1 true true WO2017060750A1 (en) 2017-04-13

Family

ID=54697611

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2015/001979 WO2017060750A1 (en) 2015-10-05 2015-10-05 Use of a withania extract for the treatment of demyelinating deseases

Country Status (1)

Country Link
WO (1) WO2017060750A1 (it)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110230551A1 (en) * 2008-09-15 2011-09-22 Leslie Gunatilaka Withaferin a analogs and uses thereof
WO2014202469A1 (fr) 2013-06-17 2014-12-24 Ethnodyne Procede d'obtention d'un extrait de plante et compositions associees

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110230551A1 (en) * 2008-09-15 2011-09-22 Leslie Gunatilaka Withaferin a analogs and uses thereof
WO2014202469A1 (fr) 2013-06-17 2014-12-24 Ethnodyne Procede d'obtention d'un extrait de plante et compositions associees

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
BRADL. M.; H. LASSMANN., ACTA NEUROPATHOL, vol. 19, 2010, pages 37 - 53
CHARLES ET AL., PNAS, vol. 97, 2000, pages 7585 - 7590
CHÉRIF RABHI ET AL: "Antiangiogenic-Like Properties of Fermented Extracts of Ayurvedic Medicinal Plants", JOURNAL OF MEDICINAL FOOD, vol. 18, no. 9, 1 September 2015 (2015-09-01), US, pages 1065 - 1072, XP055250185, ISSN: 1096-620X, DOI: 10.1089/jmf.2014.0128 *
CHIHIRO TOHDA: "ChemInform Abstract: Overcoming Several Neurodegenerative Diseases by Traditional Medicines - The Development of Therapeutic Medicines and Unraveling Pathophysiological Mechanisms", CHEMINFORM, vol. 39, no. 52, 23 December 2008 (2008-12-23), DE, pages 1159 - 1167, XP055250168, ISSN: 0931-7597, DOI: 10.1002/chin.200852253 *
GEETA MAKER-CLARK ET AL: "Integrative therapies for multiple sclerosis", DISEASE-A-MONTH., vol. 59, no. 8, 1 August 2013 (2013-08-01), US, pages 290 - 301, XP055250173, ISSN: 0011-5029, DOI: 10.1016/j.disamonth.2013.03.017 *
NAKAYAMA ET AL: "Withanoside IV improves hindlimb function by facilitating axonal growth and increase in peripheral nervous system myelin level after spinal cord injury", NEUROSCIENCE RESEARCH, ELSEVIER, SHANNON, IR, vol. 58, no. 2, 1 June 2007 (2007-06-01), pages 176 - 182, XP022100926, ISSN: 0168-0102, DOI: 10.1016/J.NEURES.2007.02.014 *

Similar Documents

Publication Publication Date Title
Oswald Human brain protein, drugs and dreams
Peng et al. The antidepressant sertraline improves the phenotype, promotes neurogenesis and increases BDNF levels in the R6/2 Huntington's disease mouse model
Bianchi et al. Early pharmacotherapy restores neurogenesis and cognitive performance in the Ts65Dn mouse model for Down syndrome
Chen et al. Trophic factors counteract elevated FGF-2-induced inhibition of adult neurogenesis
US6165515A (en) Method for treatment of osteoporosis
Viviani et al. Glia increase degeneration of hippocampal neurons through release of tumor necrosis factor-α
US5013558A (en) Pharmaceutical treatments for cerebral and neuronal diseases
Raffo et al. A pulse rapamycin therapy for infantile spasms and associated cognitive decline
Fischer et al. Cholinergic amacrine cells are not required for the progression and atropine-mediated suppression of form-deprivation myopia
Bähr et al. Astrocytes from adult rat optic nerves are nonpermissive for regenerating retinal ganglion cell axons
Chen et al. Triptolide reduces proteinuria in experimental membranous nephropathy and protects against C5b-9-induced podocyte injury in vitro
Villeneuve et al. Estrogens in tardive dyskinesia in male psychiatric patients
Miller Epidemiology, etiology, and natural treatment of seasonal affective disorder.
Xiao et al. Neuroprotection and enhanced neurogenesis by tetramethylpyrazine in adult rat brain after focal ischemia
Porter et al. Aphthous stomatitis—an overview of aetiopathogenesis and management
Bergey et al. Adverse effects of phenobarbital on morphological and biochemical development of fetal mouse spinal cord neurons in culture
WO1997049406A1 (en) Use of k-252a derivative for the treatment of peripheral or central nerve disorders, and cytokine overproduction
Flavin et al. Soluble macrophage factors trigger apoptosis in cultured hippocampal neurons
Borgers et al. Morphological changes in cysticerci of Taenia taeniaeformis after mebendazole treatment
Xu et al. Peroxisome proliferator‐activated receptor‐α agonist fenofibrate regulates IL‐12 family cytokine expression in the CNS: relevance to multiple sclerosis
Qin et al. Regulation of Th1 and Th17 cell differentiation and amelioration of experimental autoimmune encephalomyelitis by natural product compound berberine
Keller et al. Hierarchical suppression of asthma-like responses by mucosal tolerance
US20100260755A1 (en) Ibudilast and immunomodulators combination
Lagreze et al. The peptides ADNF-9 and NAP increase survival and neurite outgrowth of rat retinal ganglion cells in vitro
Stitz et al. Pathogenesis of Borna disease

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 15798547

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase in:

Ref country code: DE