WO2017020279A1

WO2017020279A1 - Uses of composition comprising polygonum capitatum and coptis roots in preparation of drugs for resisting against helicobacter pylori

Info

Publication number: WO2017020279A1
Application number: PCT/CN2015/086156
Authority: WO
Inventors: 王子厚; 周益成; 张姝; 丁莉梅; 胡伏莲; 罗昭逊; 莫非; 张丽艳; 张淑华; 金鑫; 李正亮; 周宏艳; 何云; 马领弟; 郑伟霞; 朱晓龙; 赵书琴
Original assignee: 浙江众康药业有限公司
Priority date: 2015-08-05
Filing date: 2015-08-05
Publication date: 2017-02-09

Abstract

A pharmaceutical composition comprising Polygonum capitatum and coptis roots, a preparation method therefor, and uses thereof in the preparation in drugs for resisting against bacteria, particularly Helicobacter pylori.

Description

[Invention name established by ISA according to Rule 37.2] Use of a composition comprising C. sylvestris and Coptidis in the preparation of a medicament for anti-Helicobacter pylori

Technical field

The invention belongs to the field of traditional Chinese medicine, and particularly relates to a pharmaceutical composition comprising a flower bud and a berberine, and the use thereof for preparing an antibacterial, in particular, a medicament against Helicobacter pylori.

Background technique

The head flower bud is the dry whole grass or aboveground part of the Polygonum capitatum Buch.-Ham.ex D.Don. It is a commonly used medicine in China's private and especially ethnic minority areas. The head flower is sweet, spicy and cool; it has the functions of clearing away heat and dampness, detoxification and relieving pain, and blood stasis, diuretic and drenching. In recent years, pharmacological studies have shown that the head flower bud has a wide range of pharmacological activities, including analgesic, cooling, diuretic, anti-inflammatory, antibacterial and the like.

Helicobacter pylori (H.pylori, Hp or HP in this context) is a microaerobic Gram-negative bacterium commonly found in human gastric mucosa. HP infection is an important cause of a variety of chronic stomach diseases such as peptic ulcer, gastritis, and gastric cancer. At present, the internationally recommended first-line treatment plan is based on proton pump inhibitor (PPI) or expectorant, combined with a combination of two antibiotics, the eradication rate is 90%. However, at present, these drug eradication programs have problems of toxic side effects, easy secondary resistance, double infection, and patient dependence.

Traditional Chinese medicine is a new choice for eradication of Helicobacter pylori. With the continuous exploration of the Chinese herbal medicine market, more and more Chinese medicines have shown good antibacterial effect on Hp. The research is based on single-flavor Chinese medicine. CN 102824417A (Chinese Patent Application No. 201210352856.6, published on Dec. 19, 2012) discloses a new method for the treatment of HP, or the extract thereof, is believed to have an antibacterial effect against HP in vitro. obvious.

However, Chinese medicine believes that the human body is an organic whole, and the circulation of various organs affects each other. H.pylori is a damp-heat and detoxification, which belongs to the category of "evil gas". It is difficult for a single Chinese medicine to cope with the complex and changeable condition of the disease. The role of the symptoms.

The invention is based on the single-flavored medicine of the head flower, and the other Chinese medicine is used to form the head flower bud composition, which improves the anti-Hp activity and has a good antibacterial effect on the gram-resistant bacteria, especially the methicillin-resistant epidermis. Staphylococcus, methicillin-sensitive Staphylococcus aureus, methicillin-resistant Staphylococcus aureus. And the addition of heat-clearing and detoxifying, tonic, diuresis, qi, blood circulation, dehumidification, phlegm, blood circulation, warming, dispelling cold, digestion, can reduce the adverse reactions of single-flavor drugs. The use of the pharmaceutical composition of the present invention in the preparation of a medicament for anti-Helicobacter pylori has not been reported.

Summary of the invention

Summary of invention

It is an object of the present invention to provide a pharmaceutical composition comprising a flower bud, a berberine, and a composition for the preparation of a medicament for the effective antibacterial, in particular inhibition of Helicobacter pylori.

To this end, a first aspect of the present invention provides a pharmaceutical composition, characterized in that the composition comprises a head flower bud and a berberine. Preferred compositions include 20-60 parts by weight of the head flower and 2-6 parts by weight of the berberine.

In a specific embodiment of the invention, the composition consists of the head bud, berberine, and a composition selected from any one or more of the following: (1) a heat-clearing drug; (2) a tonic drug; (3) Lishui osmotic medicine; (4) qi medicine; (5) phlegm; (6) blood circulation phlegm; (7) cooling blood hemostasis; (8) phlegm and blood stasis; (9) Wenyang Dispel cold medicine; (10) digestion medicine; (11) solution medicine.

The present invention also provides a process for the preparation of the above pharmaceutical composition extract.

The present invention also discloses formulations containing a pharmaceutical composition which is formulated with a pharmaceutically acceptable excipient into a pharmaceutically acceptable oral formulation.

The oral preparation is selected from various available regular release preparations and sustained release preparations.

The sustained-release preparation is selected from the group consisting of a skeleton type, a membrane-controlled type, an osmotic pump type, and a gastric retention type sustained-release preparation.

The gastric retention type sustained release preparation is preferably a gastric floating agent.

The invention also discloses the use of any one of the pharmaceutical compositions of the invention in the preparation of an antibacterial drug.

The pathogen is selected from the group consisting of Gram-positive methicillin-resistant Staphylococcus aureus S. aureus (Methicllin-resistant, MRSA), methicillin-sensitive Staphylococcus aureus S. aureus (Methicin-suseptable), methoxy Stalinococcus epidermidis (MRSE), methicillin-sensitive Staphylococcus epidermidis (MSSE), also selected from Gram-negative Escherichia coli, Eco ⁺ , large intestine H. (non-ESBLS) Escherichia Coli, Eco ^- , Klebsiella Klebsiella (ESBLs) K. penumonia, KPN ⁺ , Klebsiella pneumoniae (non-ESBLs) K. penumonia, Pseudomonas aeruginosa (PAE).

The invention also discloses the use of any one of the pharmaceutical compositions of the invention in the preparation of a medicament for preventing/treating Helicobacter pylori.

Detailed description of the invention

The present invention provides a novel pharmaceutical composition comprising a head flower bud and a berberine. Preferred compositions include 20-60 parts by weight of the head flower and 2-6 parts by weight of the berberine.

In a specific embodiment of the present invention, the composition consists of a flower bud, a berberine, and a composition selected from any one or more of the following: (1) a heat-clearing drug; (2) a tonic drug; 3) Lishui osmotic medicine; (4) qi medicine; (5) phlegm; (6) blood circulation phlegm; (7) cooling blood hemostasis; (8) phlegm and blood stasis; (9) temperature Yang disperse cold medicine; (10) digestion medicine; (11) solution medicine.

(1) The heat-clearing medicine according to the present invention includes, but is not limited to, dandelion, andrographis, scutellaria, phellodendron, radix isatidis, sorghum, honeysuckle, Qinpi, nasturtium, yarrow, purple diced, peony bark, eucalyptus honey, water Tuanhua, medlar, Hedyotis diffusa, Scutellaria barbata, Radix Rehmanniae, Brucea javanica, Dalbergia; but does not include head flower buds, berberine.

(2) The tonic drugs according to the present invention include, but are not limited to, licorice, Codonopsis, Atractylodes, Radix Paeoniae Alba, jujube, ginseng, tea, astragalus, and huangjing.

(3) The water-wetting agent according to the present invention includes, but is not limited to, cockroaches, knotweed, and earthworms.

(4) The qi medicines of the present invention include, but are not limited to, dried tangerine peel, woody fragrant, citrus aurantium, fragrant sage, perilla stalk, August stalk, and earthworm mustard.

(5) The sputum medicine according to the present invention includes, but is not limited to, schisandra, medlar, pomegranate peel, ebony, and jellyfish.

(6) The blood-activating and stasis-removing medicines of the present invention include, but are not limited to, Yanhusuo, Sanqi, Danshen, Shijiantong, Yujin, and Rhubarb.

(7) The cooling blood hemostasis of the present invention includes, but is not limited to, white and mantle.

(8) The phlegm-relieving peony of the present invention includes, but is not limited to, Pinellia ternata, Magnolia officinalis, Sinensis, and Ginkgo.

(9) The Wenyang cold medicine according to the present invention includes, but is not limited to, Wujing, Galang, Pepper, Dried Ginger, and Wild Ai.

(10) The anti-drug medicine of the present invention includes, but is not limited to, garlic, hawthorn, and betel nut.

(11) The solution according to the present invention includes, but is not limited to, cassia twig, ginger, perilla leaf, and Bupleurum.

Preferred heat-clearing agents are selected from the group consisting of dandelion, cork, and xanthine

Preferred tonics are selected from the group consisting of Astragalus, Atractylodes, Angelica, and Polygonatum.

The preferred water-wetting type is selected from the group consisting of knotweed and earthworm.

Preferred gas types are selected from the group consisting of woody, citrus, and fragrant.

The preferred collection is selected from the group consisting of sea bream and medlar.

The preferred blood circulation is selected from the group consisting of Corydalis, Salvia, and Panax notoginseng.

The preferred cooling blood hemostasis is selected from white and white.

The preferred phlegm-resolving hydrazine is selected from the group consisting of Pinellia ternata and Magnolia officinalis

The preferred warming and dispelling cold is selected from Wujing and Galangal.

A preferred digestion drug is selected from the group consisting of hawthorn.

A preferred solution is selected from the group consisting of cassia twig, Bupleurum, and ginger.

The preferred parts by weight of the various medicinal materials in the pharmaceutical compositions of the invention are as follows:

The composition consists of any of the above-mentioned eleven types of medicinal properties. For example, the composition is selected from any of the following groups:

The composition of 1.1 includes a head flower bud, a berberine, and a heat-clearing drug.

The composition of 1.2 includes a head flower bud, a berberine, and a tonic drug.

The composition of 1.3 includes a head flower bud, a berberine, and a water-wetting agent.

The composition described in 1.4 includes a head flower bud, a berberine, and a qi medicine.

The composition of 1.5 includes a head flower bud, a berberine, and a sputum.

The composition described in 1.6 includes a head flower bud, a berberine, a blood stasis medicine.

The composition described in 1.7 includes a head flower bud, a berberine, and a cooling blood hemostatic drug.

The composition of 1.8 includes a head flower bud, a berberine, and a phlegm-relieving peony.

The composition described in 1.9 includes the head flower bud, the berberine, and the warming and dispelling cold medicine.

The composition of 1.10 includes a head flower bud, a berberine, and a digestive.

The composition according to 1.11 includes a head flower bud, a berberine, and a solution.

The composition is composed of a medicinal composition of any one of the above-mentioned eleven types of medicinal properties:

Preferred compositions include cep, berberine, and heat-clearing drugs.

That is, the composition includes a head flower bud, a berberine, and a heat-clearing drug other than the head flower bud and the berberine.

More preferably, the composition comprises a head flower bud, a berberine and a flower selected from the group consisting of dandelion, andrographis paniculata, scutellaria, phellodendron, radix isatidis, barley, honeysuckle, genus, nasturtium, yarrow, sage, peony, eucalyptus a composition of water, flower, scorpion, Hedyotis diffusa, Scutellaria barbata, Radix Rehmanniae, Brucea javanica, Dalbergia, and various heat-clearing drugs,

Further preferred compositions are selected from any of the following groups:

(1) 20-60 parts by weight of the head flower, 2-6 parts by weight of the berberine, and 10-15 parts by weight of the dandelion;

(2) 20-60 parts by weight of the head flower, 2-6 parts by weight of the berberine, and 15-25 parts by weight of the houttuynia cordata;

(3) 20-60 parts by weight of the head flower, 2-6 parts by weight of berberine, 3-12 parts by weight of Phellodendron, 3-10 parts by weight of astragalus, and 6-10 parts by weight of medlar.

Preferred compositions include cep, berberine, and tonic.

Further preferred compositions are selected from any of the following groups:

(1) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, and 9-15 parts by weight of huangjing;

(2) preferably 10 to 90 parts by weight of the head flower, 1-10 parts by weight of berberine, and 2 to 20 parts by weight of licorice;

(3) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, and 9-18 parts by weight of Codonopsis pilosula;

(4) 20-60 parts by weight of the head flower, 2-6 parts by weight of Rhizoma Coptidis, 9-18 parts by weight of Codonopsis pilosula, and 4-9 parts by weight of licorice.

among them

(1) preferably 10 to 90 parts by weight of the head flower, 1-10 parts by weight of the berberine, and 2 to 20 parts by weight of the licorice;

(2) more preferably 20-60 parts by weight of the head flower, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice;

(3) Most preferably 30 parts by weight of the head flower, 3 parts by weight of berberine, and 6 parts by weight of licorice;

Preferred compositions include cep, berberine, and leachhinol.

Further preferred compositions are selected from any of the following groups:

(1) head flower 蓼 20-60, berberine 2-6 parts by weight, 茯苓 9-15 parts by weight;

Preferred compositions include cep, berberine, and qi.

Further preferred compositions are selected from any of the following groups:

(1) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, and 5-10 parts by weight of dried tangerine peel;

Preferred compositions include cep, berberine, and sputum.

Further preferred compositions are selected from any of the following groups:

(1) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, and 8-12 parts by weight of schisandra;

The composition consists of any of the first class of drugs, such as the head flower bud, the berberine, and the eleventh class of drugs.

The composition described in 2.1 includes a head flower bud, a berberine, a heat-clearing drug, and a tonic drug.

The composition described in 2.2 includes a head flower bud, a berberine, a heat-clearing drug, and a water-wetting agent.

The composition described in 2.3 includes a head flower bud, a coptis, a heat-clearing drug, and a qi medicine.

The composition described in 2.4 includes a head flower bud, a berberine, a heat-clearing drug, and a sputum drug.

The composition of 2.5 includes a head flower bud, a berberine, a heat-clearing drug, a blood stasis drug.

The composition described in 2.6 includes a head flower bud, a berberine, a heat-clearing drug, and a cooling blood hemostatic drug.

The composition described in 2.7 includes a head flower bud, a berberine, a heat-clearing drug, and a phlegm-dampening phlegm.

The composition described in 2.8 includes a flower bud, a berberine, a heat-clearing drug, and a warming and dispelling cold medicine.

The composition described in 2.9 includes a head flower bud, a berberine, a heat-clearing drug, and a digestive drug.

The composition described in 2.10 includes a flower bud, a coptis, a heat-clearing drug, and a drug.

The composition according to 2.11 includes a head flower bud, a berberine, a tonic drug, and a water-wetting agent.

The composition described in 2.12 includes a head flower bud, a berberine, a tonic drug, and a qi medicine.

The composition according to 2.13 includes a flower bud, a berberine, a tonic, and a sputum.

The composition according to 2.14 includes a head flower bud, a berberine, a tonic medicine, a blood stasis medicine.

The composition according to 2.15 includes a head flower bud, a berberine, a tonic medicine, and a cooling blood hemostasis.

The composition according to 2.16 includes a head flower bud, a berberine, a tonic drug, and a phlegm and blood stasis drug.

The composition described in 2.17 includes the head flower bud, the berberine, the tonic medicine, and the warming and dispelling medicine.

The composition according to 2.18 includes a flower bud, a berberine, a tonic, and a digestive.

The composition according to 2.19 includes a head flower bud, a berberine, a tonic drug, and a solution.

The composition according to 2.20 includes a head flower bud, a berberine, a water permeable medicine, and a qi medicine.

The composition according to 2.21 includes a flower bud, a berberine, a leachate, and a sputum.

The composition according to 2.22 includes a flower bud, a berberine, a leachhin, a blood stasis drug.

The composition according to 2.23 includes a head flower bud, a berberine, a water-wetting agent, and a blood-suppressing hemostatic agent.

The composition according to 2.24 includes a flower bud, a berberine, a leachhin, and a phlegm.

The composition according to 2.25 includes a head flower bud, a berberine, a water permeable medicine, and a warming and dispelling medicine.

The composition according to 2.26 includes a head flower bud, a berberine, a leachhin, and a digestive.

The composition according to 2.27 includes a head flower bud, a berberine, a water-wetting agent, and a solution.

The composition according to 2.28 includes a head flower bud, a berberine, a qi medicine, and a sputum medicine.

The composition according to 2.29 includes the head flower bud, the berberine, the qi medicine, the blood circulation phlegm medicine.

The composition according to 2.30 includes a head flower bud, a berberine, a qi medicine, and a cooling blood hemostatic medicine.

The composition according to 2.31 includes a head flower bud, a berberine, a qi medicine, and a phlegm phlegm.

The composition according to 2.32 includes a head flower bud, a berberine, a qi medicine, and a warming and dispelling medicine.

The composition according to 2.33 includes a head flower bud, a berberine, a qi medicine, and a digestive medicine.

The composition according to 2.34 includes a head flower bud, a berberine, a qi medicine, and a prescription drug.

The composition according to 2.35 includes a head flower bud, a berberine, a sputum medicine, a blood circulation phlegm medicine.

The composition according to 2.36 includes the head flower bud, the berberine, the phlegm, and the cooling blood hemostasis.

The composition according to 2.37 includes a flower bud, a berberine, a phlegm, and a phlegm.

The composition according to 2.38 includes a head flower bud, a berberine, a sputum medicine, and a warming and dispelling medicine.

The composition according to 2.39 includes a flower bud, a berberine, a sputum, and a digestive.

The composition according to 2.40 includes a flower bud, a berberine, a sputum, and a remedy.

The composition described in 2.41 includes a head flower bud, a berberine, a blood circulation phlegm medicine, and a cooling blood hemostatic medicine.

The composition according to 2.42 includes a flower bud, a berberine, a blood stasis phlegm, and a phlegm phlegm.

The composition according to 2.43 includes a flower bud, a berberine, a blood stasis medicine, and a warming and dispelling medicine.

The composition according to 2.44 includes a head flower bud, a berberine, a blood stasis medicine, and a digestive medicine.

The composition according to 2.45 includes a flower bud, a berberine, a blood stasis drug, and a remedy drug.

The composition according to 2.46 includes the head flower bud, the berberine, the cooling blood hemostasis, the phlegm and blood stasis medicine.

The composition according to 2.47 includes a flower bud, a berberine, a blood-suppressing hemostatic agent, and a warming and dispelling cold medicine.

The composition according to 2.48 includes a head flower bud, a berberine, a cooling blood hemostatic drug, and a digestive drug.

The composition according to 2.49 includes a head flower bud, a berberine, a cooling blood hemostatic drug, and a solution.

The composition according to 2.50 includes a flower bud, a berberine, a phlegm and blood stasis medicine, and a warming and dispelling medicine.

The composition according to 2.51 includes a head flower bud, a berberine, a phlegm and blood stasis medicine, and a digestive medicine.

The composition described in 2.52 includes a head flower bud, a berberine, a phlegm-dampening peony, and a remedy.

The composition described in 2.53 includes a head flower bud, a berberine, a warming and dispelling cold medicine, and a digestive medicine.

The composition described in 2.54 includes the head flower bud, the berberine, the warming and dispelling cold medicine, and the solution medicine.

The composition of 2.55 includes a head flower bud, a coptis, an anti-drug, and a solution.

The composition is composed of a medicinal composition of the first class of drugs, such as the first flower bud, the berberine, and the eleventh medicinal properties:

Preferred compositions include the head flower bud, berberine, tonic, and water-wetting.

Further preferred compositions are selected from any of the following groups:

(1) 20-60 parts by weight of the head flower, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, 9-15 parts by weight of hydrazine;

(2) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, 9-18 parts by weight of Codonopsis pilosula, and 9-15 parts by weight of medlar;

(3) 20-60 parts by weight of the head flower, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, 9-18 parts by weight of Codonopsis pilosula, 9-15 parts by weight of 茯苓;

(4) 20-60 parts by weight of the head flower, 2-6 parts by weight of berberine, 3-9 parts by weight of ginseng, 6-12 parts by weight of Atractylodes, 2-6 parts by weight of licorice, 9-15 parts by weight of hydrazine;

Preferred compositions include cep, berberine, tonic, and qi.

Further preferred compositions are selected from any of the following groups:

(1) preferably 20-60 parts by weight of the head flower, 2-6 parts by weight of berberine, 9-18 parts by weight of Codonopsis pilosula, 5-10 parts by weight of dried tangerine peel;

(2) preferably 20-60 parts by weight of the head flower, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, 5-10 parts by weight of dried tangerine peel;

(3) Further preferably, 20-60 parts by weight of the head flower, 2-6 parts by weight of Rhizoma Coptidis, 9-18 parts by weight of Codonopsis pilosula, 4-9 parts by weight of licorice, and 5-10 parts by weight of dried tangerine peel.

Preferred compositions include cep, berberine, tonic, and expectorant.

Further preferred compositions are selected from any of the following groups:

(1) 20-60 parts by weight of the head flower, 2-6 parts by weight of berberine, 9-18 parts by weight of Codonopsis pilosula, and 8-12 parts by weight of Schisandra;

(2) 20-60 parts by weight of the head flower, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, and 8-12 parts by weight of Schisandra;

(3) 20-60 parts by weight of the head flower, 2-6 parts by weight of berberine, 9-18 parts by weight of Codonopsis pilosula, 4-9 parts by weight of licorice, and 8-12 parts by weight of Schisandra;

The composition comprising the group of flower head, berberine, tonic, and warming cold medicine is selected from any one of the following groups:

(1) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, 6-15 parts by weight of white peony, 2-5 parts by weight of sorghum

The composition comprising the group of flower head, berberine, tonic, and drug solution is selected from any one of the following groups:

(1) 20-60 parts by weight of the head flower, 2-6 parts by weight of berberine, 2-6 parts by weight of licorice, 6-15 parts by weight of white peony, 6-15 parts by weight of jujube, 3-10 parts by weight of cassia twig, Ginger 3-10 parts by weight

Preferred compositions include scutellaria, berberine, lysine, and qi.

Further preferred compositions are selected from any of the following groups:

(1) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, 9-15 parts by weight of medlar, and 5-10 parts by weight of dried tangerine peel;

Preferred compositions include scutellaria, berberine, lysine, and sputum.

Further preferred compositions are selected from any of the following groups:

(1) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, 9-15 parts by weight of quinone, and 8-12 parts by weight of schisandra;

Preferred compositions include cep, berberine, qi, and sputum.

Further preferred compositions are selected from any of the following groups:

(1) 20-60 parts by weight of the head flower, 2-6 parts by weight of berberine, 5-10 parts by weight of dried tangerine peel, and 8-12 parts by weight of Schisandra;

The composition consists of the head flower bud, the berberine, and any of the above-mentioned eleven types of drugs.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, and a water-wetting agent.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, and a qi medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, and a sputum medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a blood circulation medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, and a cooling blood hemostatic drug.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, and a phlegm-dampening phlegm.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, and a warming and dispelling cold medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, and a digestive drug.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, and a solution.

The composition includes a flower bud, a coptis, a heat-clearing drug, a water-wetting drug, and a gas-making drug.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, and a phlegm-receiving drug.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, and a blood-activating and stasis drug.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, and a cooling blood-stopping drug.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting agent, and a phlegm-dampening phlegm.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting agent, and a warm-yang dispersing drug.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting agent, and a digestive drug.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting agent, and a solution.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a qi medicine, and a sputum medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a qi medicine, a blood circulation phlegm medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a qi medicine, and a cooling blood hemostatic medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a qi medicine, and a phlegm-dampening medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a qi medicine, and a warm-yang dispersing medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a qi medicine, and a digestion drug.

The composition includes a flower bud, a coptis, a heat-clearing drug, a qi medicine, and a remedy.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a phlegm-removing drug, and a blood-activating phlegm.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a sputum medicine, and a cooling blood hemostatic medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a phlegm-receiving drug, and a phlegm-dampening phlegm.

The composition includes a flower bud, a berberine, a heat-clearing drug, a sputum medicinal agent, and a warming and dispelling cold medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a sputum medicinal agent, and a digestive medicinal agent.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a sputum drug, and a remedy drug.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a blood-activating phlegm, and a cooling blood-stopping drug.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a blood-activating phlegm medicine, and a phlegm-dampening medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a blood-activating phlegm medicine, and a warm-yang dispersing medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a blood stasis drug, and a digestion drug.

The composition includes a flower bud, a coptis, a heat-clearing drug, a blood stasis drug, and a drug.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a cooling blood hemostatic drug, and a phlegm-dampening phlegm.

The composition includes a flower bud, a berberine, a heat-clearing drug, a cooling blood hemostasis, and a warming and dispelling cold medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a cooling blood hemostatic drug, and a digestive drug.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a cooling blood hemostatic drug, and a remedy drug.

The composition includes a flower bud, a berberine, a heat-clearing drug, a phlegm-dampening phlegm, and a warming and dispelling cold medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a phlegm-dampening phlegm, and a digestive medicinal.

The composition includes a flower bud, a berberine, a heat-clearing drug, a phlegm-dampening phlegm, and a remedy.

The composition includes a flower bud, a berberine, a heat-clearing drug, a warming and dispelling cold medicine, and a digestive medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a warming and dispelling cold medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a digestive drug, and a solution.

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, and a qi medicine.

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, and a phlegm.

The composition includes a head flower bud, a berberine, a tonic drug, a water-sparing osmotic drug, a blood-activating phlegm medicine.

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, and a cooling blood-stopping drug.

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, and a phlegm-dampening drug.

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, and a warming and dispelling medicine.

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, and a digestive drug.

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, and a solution.

The composition includes a head flower bud, a berberine, a tonic drug, a qi medicine, and a sputum medicine.

The composition includes a head flower bud, a berberine, a tonic drug, a qi medicine, a blood circulation phlegm medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a qi medicine, and a cooling blood hemostatic medicine.

The composition includes a head flower bud, a berberine, a tonic drug, a qi medicine, and a phlegm and blood stasis medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a qi medicine, and a warm and cold medicine.

The composition includes a head flower bud, a berberine, a tonic drug, a qi medicine, and a digestion drug.

The composition includes a head flower bud, a berberine, a tonic drug, a qi medicine, and a prescription drug.

The composition includes a head flower bud, a berberine, a tonic medicine, a sputum medicine, a blood circulation phlegm medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a sputum medicine, and a cooling blood hemostatic medicine.

The composition includes a head flower bud, a berberine, a tonic drug, a phlegm, and a phlegm.

The composition includes a head flower bud, a berberine, a tonic medicine, a sputum medicine, and a warming and dispelling medicine.

The composition includes a head flower bud, a berberine, a tonic, a sputum, and a digestive.

The composition includes a head flower bud, a berberine, a tonic drug, a sputum drug, and a remedy drug.

The composition includes a head flower bud, a berberine, a tonic medicine, a blood circulation phlegm medicine, and a cooling blood hemostatic medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a blood circulation phlegm medicine, and a phlegm and blood stasis medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a blood circulation phlegm medicine, and a warm and cold medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a blood stasis medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a blood stasis medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a cooling blood hemostasis, and a phlegm and blood stasis medicine.

The composition includes a head flower bud, a berberine, a tonic drug, a cooling blood hemostasis, and a warming and dispelling cold medicine.

The composition includes a head flower bud, a berberine, a tonic drug, a cooling blood hemostatic drug, and a digestive drug.

The composition includes a head flower bud, a berberine, a tonic medicine, a cooling blood hemostatic medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a phlegm-dampening phlegm, and a warming and dispelling medicine.

The composition includes a head flower bud, a berberine, a tonic drug, a phlegm and blood stasis drug, and a digestive drug.

The composition includes a flower bud, a berberine, a tonic, a phlegm, and a remedy.

The composition includes a head flower bud, a berberine, a tonic medicine, a warming and dispelling medicine, and a digestive medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a warming and dispelling medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a tonic drug, a digestive drug, and a solution.

The composition includes a head flower bud, a berberine, a water permeable medicine, a qi medicine, and a sputum medicine.

The composition includes a head flower bud, a berberine, a leachhin, a qi medicine, a blood circulation phlegm medicine.

The composition includes a head flower bud, a berberine, a water-wetting agent, a qi medicine, and a cooling blood hemostatic medicine.

The composition includes a head flower bud, a berberine, a water-wetting agent, a qi medicine, and a phlegm-dampening medicine.

The composition includes a head flower bud, a berberine, a water-wetting agent, a qi medicine, and a warm-yang medicine.

The composition includes a head flower bud, a berberine, a water permeable medicine, a qi medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a water-wetting agent, a qi medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a leachhin, a phlegm, a blood stasis drug.

The composition includes a head flower bud, a berberine, a leachhin, a phlegm, and a blood-suppressing hemostatic agent.

The composition includes a flower bud, a berberine, a leachhin, a phlegm, and a phlegm.

The composition includes a head flower bud, a berberine, a water-wetting agent, a phlegm-receiving medicine, and a warm-yang dispersing medicine.

The composition includes a head flower bud, a berberine, a leachate, a phlegm, and a digestive.

The composition includes a flower bud, a berberine, a leachate, a phlegm, and a remedy.

The composition includes a head flower bud, a berberine, a water-wetting agent, a blood-activating phlegm medicine, and a cooling blood-stopping medicine.

The composition includes a head flower bud, a berberine, a water-wetting agent, a blood-activating phlegm, and a phlegm-dampening phlegm.

The composition includes a head flower bud, a berberine, a water-wetting agent, a blood-activating phlegm, and a warm-yang dispersing medicine.

The composition includes a flower bud, a berberine, a leachhin, a blood stasis drug, and a digestive drug.

The composition includes a head flower bud, a berberine, a water-wetting agent, a blood-activating phlegm, and a remedy.

The composition includes a head flower bud, a berberine, a water-wetting drug, a cooling blood-stopping drug, and a phlegm-dampening phlegm.

The composition includes a head flower bud, a berberine, a water-wetting agent, a cooling blood-stopping drug, and a warm-yang dispersing medicine.

The composition includes a head flower bud, a berberine, a water-wetting drug, a cooling blood hemostatic drug, and a digestive drug.

The composition includes a head flower bud, a berberine, a water-wetting agent, a cooling blood hemostatic drug, and a solution.

The composition includes a head flower bud, a berberine, a water-wetting agent, a phlegm-dampening phlegm, and a warm-yang dispersing medicine.

The composition includes a head flower bud, a berberine, a water-wetting agent, a phlegm-dampening medicinal herb, and a digestive medicinal agent.

The composition includes a head flower bud, a berberine, a water-wetting agent, a phlegm-dampening phlegm, and a remedy.

The composition includes a head flower bud, a berberine, a water-wetting agent, a warm-yang dispersing medicine, and a digestive medicine.

The composition includes a head flower bud, a berberine, a water-wetting agent, a warm-yang dispersing medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a water-wetting agent, an anti-drug, and a solution.

The composition includes a head flower bud, a berberine, a qi medicine, a sputum medicine, a blood circulation phlegm medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a phlegm medicine, and a cooling blood hemostatic medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a phlegm medicine, and a phlegm and blood stasis medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a sputum medicine, and a warm and cold medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a sputum medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a sputum medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a blood circulation phlegm medicine, and a cooling blood hemostatic medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a blood circulation phlegm medicine, and a phlegm phlegm medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a blood circulation phlegm medicine, and a warm yang medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a blood circulation phlegm medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a blood circulation phlegm medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a cooling blood hemostasis, and a phlegm and blood stasis medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a cooling blood hemostasis, and a warming and dispelling medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a cooling blood hemostatic medicine, and a digestive medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a cooling blood hemostatic medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a phlegm-dampening phlegm, and a warm-yang dispelling medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a phlegm and blood stasis medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a phlegm phlegm, and a remedy.

The composition includes a head flower bud, a berberine, a qi medicine, a Wenyang cold medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a Wenyang cold medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a digestion medicine, and a prescription medicine.

The composition includes a head flower bud, a berberine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine.

The composition includes a flower bud, a berberine, a phlegm, a blood stasis, and a phlegm.

The composition includes a head flower bud, a berberine, a phlegm, a blood circulation phlegm, and a warm yang medicine.

The composition includes a head flower bud, a berberine, a sputum medicine, a blood circulation phlegm medicine, and a digestion medicine.

The composition includes a flower bud, a berberine, a phlegm, a blood stasis drug, and a remedy.

The composition includes a head flower bud, a berberine, a sputum medicine, a cooling blood hemostatic medicine, and a phlegm and blood stasis medicine.

The composition includes a head flower bud, a berberine, a sputum medicine, a cooling blood hemostasis, and a warming and dispelling medicine.

The composition includes a head flower bud, a berberine, a sputum medicine, a cooling blood hemostatic medicine, and a digestive medicine.

The composition includes a head flower bud, a berberine, a sputum medicine, a cooling blood hemostatic medicine, and a remedy medicine.

The composition includes a flower bud, a berberine, a phlegm, a phlegm, and a phlegm medicine.

The composition includes a head flower bud, a berberine, a phlegm, a phlegm, and a digestive.

The composition includes a head flower bud, a berberine, a phlegm, a phlegm, and a remedy.

The composition includes a head flower bud, a berberine, a phlegm, a warming and dispelling medicine, and a digestive medicine.

The composition includes a head flower bud, a berberine, a phlegm, a warming and dispelling medicine, and a remedy.

The composition includes a flower bud, a berberine, a sputum, a digestive, and a remedy.

The composition includes a head flower bud, a berberine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a phlegm and blood stasis medicine.

The composition includes a head flower bud, a berberine, a blood circulation phlegm, a cooling blood hemostasis, and a warming and dispelling cold medicine.

The composition includes a head flower bud, a berberine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a blood circulation phlegm medicine, a phlegm dampness phlegm medicine, and a yang yang medicine.

The composition includes a flower bud, a berberine, a blood stasis phlegm, a phlegm phlegm, and a digestive.

The composition includes a flower bud, a berberine, a blood stasis phlegm, a phlegm phlegm, and a remedy.

The composition includes a flower bud, a berberine, a blood stasis drug, a warming and dispelling cold medicine, and a digestive medicine.

The composition includes a head flower bud, a berberine, a blood circulation phlegm, a warming and dispelling medicine, and a remedy.

The composition includes a flower bud, a berberine, a blood stasis, a digestive, and a remedy.

The composition includes a head flower bud, a berberine, a blood-suppressing hemostatic agent, a phlegm-dampening phlegm medicine, and a warm-yang dispersing medicine.

The composition includes a flower bud, a berberine, a blood-suppressing hemostatic agent, a phlegm-dampening phlegm, and a digestive medicinal.

The composition includes a head flower bud, a berberine, a cooling blood hemostasis, a phlegm-dampening phlegm, and a remedy.

The composition includes a head flower bud, a berberine, a cooling blood hemostasis, a warming and dispelling cold medicine, and a digestive medicine.

The composition includes a head flower bud, a berberine, a cooling blood hemostasis, a warming and dispelling cold medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a cooling blood hemostatic drug, a digestive drug, and a remedy drug.

The composition includes a flower bud, a berberine, a phlegm and blood stasis medicine, a warming and dispelling medicine, and a digestive medicine.

The composition includes a head flower bud, a berberine, a phlegm-dampening phlegm, a warming and dispelling medicine, and a remedy.

The composition includes a head flower bud, a berberine, a phlegm-dampening peony, a digestive medicinal agent, and a remedy drug.

The composition includes a flower bud, a berberine, a yangyang cold medicine, a digestive medicine, and a remedy.

The composition is composed of a medicinal composition of the head bud, berberine, and any of the above eleven types of medicinal properties:

Preferred compositions include head flower buds, berberine, tonic medicine, water osmotic drug, and qi medicine.

Further preferred compositions are selected from any of the following groups:

(1) 10-90 parts by weight of the head flower, 1-10 parts by weight of Rhizoma Coptidis, 3-50 parts by weight of Codonopsis pilosula, 3-30 parts by weight of medlar, 2-20 parts by weight of dried tangerine peel;

(2) 20-60 parts by weight of the head flower, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel;

(3) 20-60 parts by weight of the head flower, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, 9-18 parts by weight of Codonopsis pilosula, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel;

among them

(1) preferably 10-90 parts by weight of the head flower, 1-10 parts by weight of Rhizoma Coptidis, 3-50 parts by weight of Codonopsis pilosula, 3-30 parts by weight of medlar, 2-20 parts by weight of dried tangerine peel;

(2) more preferably 20-60 parts by weight of the head flower, 2-6 parts by weight of Rhizoma Coptidis, 9-18 parts by weight of Codonopsis pilosula, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel;

(3) Most preferably 30-60 parts by weight of the head flower, 3 parts by weight of Rhizoma Coptidis, 10 parts by weight of Codonopsis pilosula, 10 parts by weight of medlar, and 6 parts by weight of dried tangerine peel;

Preferred compositions include cep, berberine, tonic, diuretic, and phlegm.

Further preferred compositions are selected from any of the following groups:

(1) 10-90 parts by weight of the head flower, 1-10 parts by weight of Rhizoma Coptidis, 3-50 parts by weight of Codonopsis pilosula, 3-30 parts by weight of medlar, and 2-20 parts by weight of Schisandra;

(2) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, 9-15 parts by weight of medlar, and 8-12 parts by weight of schisandra;

(3) 20-60 parts by weight of the head flower, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, 9-18 parts by weight of Codonopsis pilosula, 9-15 parts by weight of medlar, 8-12 parts by weight of Schisandra,

among them

(1) preferably 10 to 90 parts by weight of the head flower, 1-10 parts by weight of Rhizoma Coptidis, 3 to 50 parts by weight of Codonopsis pilosula, 3 to 30 parts by weight of medlar, and 2 to 20 parts by weight of Schisandra;

(2) more preferably 20-60 parts by weight of the head flower, 2-6 parts by weight of berberine, 9-18 parts by weight of Codonopsis pilosula, 9-15 parts by weight of medlar, and 8-12 parts by weight of Schisandra;

(3) Most preferably 30-60 parts by weight of the head flower, 3 parts by weight of berberine, 10 parts by weight of Codonopsis pilosula, 10 parts by weight of hydrazine, Schisandra 10 parts by weight.

Preferred compositions include cep, berberine, tonic, qi, and phlegm.

Further preferred compositions are selected from any of the following groups:

(1) 20-60 parts by weight of the head flower, 2-6 parts by weight of Rhizoma Coptidis, 9-18 parts by weight of Codonopsis pilosula, 5-10 parts by weight of dried tangerine peel, and 8-12 parts by weight of Schisandra;

(2) 20-60 parts by weight of the head flower, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, 5-10 parts by weight of dried tangerine peel, and 8-12 parts by weight of Schisandra;

(3) 20-60 parts by weight of the head flower, 2-6 parts by weight of Rhizoma Coptidis, 9-18 parts by weight of Codonopsis pilosula, 4-9 parts by weight of licorice, 5-10 parts by weight of dried tangerine peel, and 8-12 parts by weight of Schisandra.

A preferred composition comprising a group of head flower buds, berberine, tonic medicine, Wenyang cold medicine, and a solution medicine is selected from any one of the following groups:

(1) 20-60 parts by weight of head flower, 2-6 parts by weight of berberine, 2-6 parts by weight of licorice, 9-30 parts by weight of astragalus, 9-18 parts by weight of Codonopsis pilosula, 6-15 parts by weight of white peony, jujube 6 to 15 parts by weight, 3 to 6 parts by weight of galangal, 3 to 10 parts by weight of dried ginger, and 3 to 10 parts by weight of cassia twig.

Preferred compositions include scutellaria, berberine, lysine, qi, and sputum.

Further preferred compositions are selected from the group consisting of:

(1) 20-60 parts by weight of the head flower, 2-6 parts by weight of berberine, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, and 8-12 parts by weight of Schisandra;

The composition consists of the head flower bud, berberine, and any of the above four drugs.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting agent, and a qi medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, and a phlegm-receiving drug.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, and a blood-activating and stasis drug.

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, and a cooling blood-stopping drug.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting agent, and a phlegm-dampening medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting agent, and a warm-yang dispersing medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, and a digestive drug.

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, and a solution.

The composition includes a flower bud, a coptis, a heat-clearing drug, a tonic drug, a qi medicine, and a sputum medicine.

The composition includes a flower bud, a coptis, a heat-clearing drug, a tonic drug, a qi medicine, a blood circulation phlegm medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a qi medicine, and a cooling blood hemostatic medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a qi medicine, and a phlegm-dampening medicine.

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a qi medicine, and a warm-yang dispersing medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a qi medicine, and a digestion drug.

The composition includes a flower bud, a coptis, a heat-clearing drug, a tonic drug, a qi medicine, and a remedy.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a sputum medicine, a blood circulation medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a sputum medicine, and a cooling blood hemostatic medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a phlegm medicine, and a phlegm-dampening medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a phlegm-receiving drug, and a warm-yang dispersing drug.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a sputum drug, and a digestion drug.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a sputum drug, and a remedy drug.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a blood circulation phlegm medicine, and a cooling blood hemostatic medicine.

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a blood-activating phlegm, and a phlegm-dampening phlegm.

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a blood-activating phlegm, and a warming and dispelling cold medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a blood circulation phlegm medicine, and a digestion medicine.

The composition includes a flower bud, a coptis, a heat-clearing drug, a tonic drug, a blood stasis drug, and a drug.

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a blood-suppressing hemostatic drug, and a phlegm-dampening phlegm.

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a cooling blood hemostasis, and a warming and dispelling cold medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a cooling blood hemostatic medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a cooling blood hemostatic medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a phlegm-dampening phlegm medicine, and a warm-yang dispersing medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a phlegm-dampening phlegm medicine, and a digestive medicine.

The composition includes a flower bud, a coptis, a heat-clearing drug, a tonic drug, a phlegm-dampening phlegm, and a remedy.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a warm-yang dispersing medicine, and a digestive medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a warm-yang dispersing medicine, and a solution medicine.

The composition includes a head flower bud, a coptis, a heat-clearing drug, a tonic drug, a digestion drug, and a drug solution.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a qi medicine, and a sputum medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a qi medicine, a blood circulation phlegm medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a qi medicine, and a cooling blood-stopping medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting agent, a qi medicine, and a phlegm-dampening phlegm.

The composition includes a flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a qi medicine, and a warm-yang dispersing medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a gas-making drug, and a digestion drug.

The composition includes a flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a qi medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a phlegm-receiving drug, a blood-activating phlegm medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a phlegm-receiving drug, and a cooling blood-stopping drug.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a phlegm-receiving drug, and a phlegm-dampening phlegm.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a phlegm-receiving drug, and a warm-yang dispersing drug.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting agent, a phlegm-receiving drug, and a digestive drug.

The composition includes a flower bud, a coptis, a heat-clearing drug, a water-wetting drug, a phlegm-receiving drug, and a remedy drug.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a water-wetting drug, a blood-activating phlegm medicine, and a cooling blood-stopping medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting agent, a blood-activating phlegm, and a phlegm-dampening phlegm.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a blood-activating phlegm drug, and a warm-yang dispersing drug.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a blood-activating phlegm drug, and a food-eliminating drug.

The composition includes a flower bud, a coptis, a heat-clearing drug, a water-wetting drug, a blood-activating phlegm, and a remedy.

The composition includes a flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a cooling blood-stopping drug, and a phlegm-dampening phlegm.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a cooling blood-stopping drug, and a warm-yang dispersing drug.

The composition includes a flower bud, a coptis, a heat-clearing drug, a water-wetting drug, a cooling blood-stopping drug, and a digestive drug.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a cooling blood-stopping drug, and a solution-solving drug.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting agent, a phlegm-dampening phlegm, and a warm-yang dispersing drug.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a phlegm-dampening phlegm, and a food-eliminating drug.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting agent, a phlegm-dampening phlegm, and a remedy.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a warm-yang dispersing drug, and a digestive drug.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting agent, a warm-yang dispersing drug, and a solution-solving drug.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting agent, a digestion-eliminating drug, and a solution-solving drug.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a qi medicine, a sputum medicine, a blood circulation phlegm medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a qi medicine, a phlegm medicine, and a cooling blood hemostatic medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a qi medicine, a phlegm medicine, and a phlegm-dampening medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a qi medicine, a sputum medicine, and a Wenyang cold medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a qi medicine, a sputum medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a qi medicine, a sputum medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a qi medicine, a blood circulation phlegm medicine, and a cooling blood hemostatic medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a qi medicine, a blood circulation phlegm medicine, and a phlegm-dampening phlegm medicine.

The composition includes a flower bud, a berberine, a heat-clearing medicine, a qi medicine, a blood-activating phlegm medicine, and a warm-yang dispersing medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a qi medicine, a blood circulation phlegm medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a qi medicine, a blood circulation phlegm medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a qi medicine, a cooling blood hemostasis, and a phlegm-dampening phlegm.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a qi medicine, a cooling blood hemostasis, and a warm-yang dispersing medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a qi medicine, a cooling blood hemostatic medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a qi medicine, a cooling blood hemostatic medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a qi medicine, a phlegm-dampening phlegm medicine, and a warm-yang dispersing medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a qi medicine, a phlegm-dampening phlegm medicine, and a digestive medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a qi medicine, a phlegm-dampening phlegm medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a qi medicine, a Wenyang cold medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a qi medicine, a warm-yang dispersing medicine, and a solution medicine.

The composition includes a flower bud, a coptis, a heat-clearing drug, a qi medicine, a digestion drug, and a remedy drug.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a sputum medicinal medicine, a blood circulation phlegm medicine, and a cooling blood hemostatic medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a sputum medicinal medicine, a blood circulation phlegm medicine, and a phlegm-dampening phlegm medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a sputum medicinal medicine, a blood-activating phlegm medicine, and a warm-yang dispersing medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a sputum medicinal herb, a blood-activating phlegm drug, and a digestion drug.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a sputum medicinal medicine, a blood-activating phlegm medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a sputum medicine, a cooling blood hemostatic medicine, and a phlegm-dampening phlegm medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a sputum medicine, a cooling blood hemostasis medicine, and a warm-yang cold medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a sputum medicine, a cooling blood hemostatic medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a sputum medicine, a cooling blood hemostatic medicine, and a remedy medicine.

The composition includes a flower bud, a berberine, a heat-clearing drug, a phlegm-receiving medicinal herb, a phlegm-dampening phlegm drug, and a warm-yang dispersing drug.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a sputum medicinal herb, a phlegm-dampening phlegm drug, and a digestive medicinal drug.

The composition includes a flower bud, a coptis, a heat-clearing drug, a sputum medicinal herb, a phlegm-dampening phlegm drug, and a remedy drug.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a sputum medicinal agent, a warming and dispelling cold medicine, and a digestive medicinal agent.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a sputum medicine, a Wenyang cold medicine, and a remedy medicine.

The composition includes a flower bud, a berberine, a heat-clearing drug, a sputum medicinal drug, a digestive medicinal drug, and a remedy drug.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, and a phlegm-dampening phlegm medicine.

The composition includes a flower bud, a berberine, a heat-clearing medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, and a warm-yang dispersing medicine.

The composition includes a flower bud, a berberine, a heat-clearing drug, a blood-activating phlegm, a cooling blood-stopping drug, and a digestive drug.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a blood-activating phlegm medicine, a cooling blood hemostatic medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a blood-activating phlegm medicine, a phlegm-dampening phlegm medicine, and a warm-yang dispersing medicine.

The composition includes a flower bud, a berberine, a heat-clearing drug, a blood stasis drug, a phlegm-dampening phlegm drug, and a digestion drug.

The composition includes a flower bud, a berberine, a heat-clearing drug, a blood stasis drug, a phlegm-dampening phlegm drug, and a remedy drug.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a blood-activating phlegm medicine, a warm-yang dispersing medicine, and a digestive medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a blood-activating phlegm medicine, a warm-yang dispersing medicine, and a remedy medicine.

The composition includes a flower bud, a berberine, a heat-clearing drug, a blood stasis drug, a digestion drug, and a drug solution.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a cooling blood hemostatic medicine, a phlegm-dampening phlegm medicine, and a warm-yang dispersing medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a cooling blood stopping medicine, a phlegm-dampening phlegm medicine, and a digestive medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a cooling blood hemostatic medicine, a phlegm-dampening phlegm medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a cooling blood hemostasis, a warming and dispelling cold medicine, and a digestive medicine.

The composition includes a flower bud, a coptis, a heat-clearing drug, a cooling blood-stopping drug, a warm-yang dispersing drug, and a solution-solving drug.

The composition includes a flower bud, a berberine, a heat-clearing drug, a cooling blood hemostatic drug, a digestive drug, and a remedy drug.

The composition includes a flower bud, a berberine, a heat-clearing drug, a phlegm-dampening phlegm, a warming and dispelling cold medicine, and a digestive medicine.

The composition includes a flower bud, a berberine, a heat-clearing drug, a phlegm-dampening phlegm, a warming and dispelling cold medicine, and a remedy.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a phlegm-dampening phlegm, an anti-drug, and a remedy.

The composition includes a flower bud, a berberine, a heat-clearing drug, a warming and dispelling cold medicine, a digestive medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, a qi medicine, and a sputum medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting agent, a qi medicine, a blood circulation medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting agent, a qi medicine, and a blood-suppressing medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting agent, a qi medicine, and a phlegm-dampening medicine.

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, a qi medicine, and a warm-yang medicine.

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, a qi medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, a qi medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting agent, a sputum medicine, a blood circulation medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting agent, a phlegm-receiving medicine, and a cooling blood-stopping medicine.

The composition includes a head flower bud, a berberine, a tonic drug, a leachhin, a phlegm, and a phlegm.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting agent, a sputum medicine, and a warm-yang medicine.

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a phlegm drug, and a digestion drug.

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a sputum drug, and a remedy drug.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting agent, a blood-activating phlegm medicine, and a cooling blood-stopping medicine.

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, a blood-activating phlegm, and a phlegm-dampening phlegm.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting agent, a blood-activating phlegm medicine, and a warm-yang medicine.

The composition includes a head flower bud, a berberine, a tonic drug, a water-sparing osmotic drug, a blood-activating phlegm drug, and a digestive drug.

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, a blood-activating phlegm, and a solution.

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a cooling blood-stopping drug, and a phlegm-dampening phlegm.

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a cooling blood-stopping drug, and a warm-yang dispersing drug.

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a cooling blood-stopping drug, and a digestive drug.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a cooling blood hemostatic drug, and a solution medicine.

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, a phlegm-dampening phlegm, and a warm-yang dispersing drug.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting agent, a phlegm-dampening phlegm, and a digestive medicine.

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, a phlegm-dampening phlegm, and a remedy.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting agent, a warm-yang dispersing medicine, and a digestive medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting agent, a warm-yang dispersing medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, a digestive drug, and a solution.

The composition includes a head flower bud, a berberine, a tonic medicine, a qi medicine, a sputum medicine, a blood circulation phlegm medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a qi medicine, a sputum medicine, a cooling blood hemostatic medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a qi medicine, a phlegm medicine, and a phlegm and blood stasis medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a qi medicine, a sputum medicine, and a warming medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a qi medicine, a sputum medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a qi medicine, a sputum medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a qi medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a qi medicine, a blood circulation phlegm medicine, a phlegm and blood stasis medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a qi medicine, a blood circulation phlegm medicine, and a warm yang medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a qi medicine, a blood circulation phlegm medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a qi medicine, a blood circulation phlegm medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a qi medicine, a cooling blood hemostasis, and a phlegm and blood stasis medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a qi medicine, a cooling blood hemostasis, and a warm and cold medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a qi medicine, a cooling blood hemostatic medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a qi medicine, a cooling blood hemostatic medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a qi medicine, a phlegm and blood stasis medicine, and a warming and dispelling medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a qi medicine, a phlegm-dampening phlegm medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a qi medicine, a phlegm and blood stasis medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a qi medicine, a Wenyang cold medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a qi medicine, a Wenyang cold medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a tonic drug, a qi medicine, a digestion drug, and a remedy drug.

The composition includes a head flower bud, a berberine, a tonic medicine, a sputum medicine, a blood circulation phlegm medicine, and a cooling blood hemostatic medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a sputum medicine, a blood circulation phlegm medicine, and a phlegm phlegm medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a sputum medicine, a blood circulation phlegm medicine, and a warm and yang medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a sputum medicine, a blood circulation phlegm medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a sputum medicine, a blood circulation phlegm medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a sputum medicine, a cooling blood hemostatic medicine, and a phlegm and blood stasis medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a sputum medicine, a cooling blood hemostasis, and a warming and dispelling medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a sputum medicine, a cooling blood hemostatic medicine, and a digestive medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a sputum medicine, a cooling blood hemostatic medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a phlegm medicine, a phlegm and blood stasis medicine, and a warming and dispelling medicine.

The composition includes a flower bud, a berberine, a tonic, a phlegm, a phlegm, and a digestive.

The composition includes a head flower bud, a berberine, a tonic medicine, a phlegm, a phlegm, and a remedy.

The composition includes a head flower bud, a berberine, a tonic drug, a sputum medicinal agent, a warming and dispelling medicinal agent, and a digestive medicinal agent.

The composition includes a head flower bud, a berberine, a tonic drug, a sputum medicinal agent, a warming and dispelling cold medicine, and a remedy drug.

The composition includes a head flower bud, a berberine, a tonic drug, a sputum drug, a digestive drug, and a remedy drug.

The composition includes a head flower bud, a berberine, a tonic medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a phlegm and blood stasis medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a blood circulation phlegm medicine, a cooling blood hemostasis medicine, and a warm and cold medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a blood circulation phlegm medicine, a phlegm dampness phlegm medicine, and a yang yang medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a blood stasis medicine, a phlegm and blood stasis medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a blood stasis medicine, a phlegm phlegm medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a blood circulation phlegm medicine, a yangyang cold medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a blood circulation phlegm medicine, a Wenyang cold medicine, and a solution medicine.

The composition includes a flower bud, a berberine, a tonic, a blood stasis, a digestive, and a remedy.

The composition includes a head flower bud, a berberine, a tonic medicine, a cooling blood hemostasis, a phlegm and blood stasis medicine, and a warming and dispelling medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a cooling blood hemostasis, a phlegm and blood stasis medicine, and a digestive medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a cooling blood hemostasis, a phlegm and blood stasis medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a tonic drug, a cooling blood hemostasis, a warming and dispelling cold medicine, and a digestive medicine.

The composition includes a head flower bud, a berberine, a tonic drug, a cooling blood hemostasis, a warming and dispelling cold medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a cooling blood hemostasis, a digestion medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a phlegm-dampening phlegm, a warm-yang dispersing medicine, and a digestive medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a phlegm-dampening phlegm, a warming and dispelling medicine, and a remedy.

The composition includes a head flower bud, a berberine, a tonic drug, a phlegm-dampening phlegm, an anti-drug, and a remedy.

The composition includes a head flower bud, a berberine, a tonic drug, a warming and dispelling medicine, a digestion drug, and a solution.

The composition includes a head flower bud, a berberine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine.

The composition includes a head flower bud, a berberine, a water-wetting drug, a qi medicine, a sputum medicine, and a cooling blood hemostatic medicine.

The composition includes a head flower bud, a berberine, a water permeable medicine, a qi medicine, a phlegm medicine, and a phlegm phlegm.

The composition includes a head flower bud, a berberine, a water-wetting agent, a qi medicine, a phlegm medicine, and a warm-yang medicine.

The composition includes a head flower bud, a berberine, a water permeable medicine, a qi medicine, a sputum medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a water-wetting agent, a qi medicine, a sputum medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a leachhin, a qi medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine.

The composition includes a head flower bud, a berberine, a leachhin, a qi medicine, a blood circulation phlegm medicine, and a phlegm phlegm medicine.

The composition includes a head flower bud, a berberine, a leachhin, a qi medicine, a blood circulation phlegm medicine, and a warm yang medicine.

The composition includes a head flower bud, a berberine, a leachhin, a qi medicine, a blood circulation phlegm medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a leachhin, a qi medicine, a blood circulation phlegm medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a water-wetting agent, a qi medicine, a cooling blood hemostasis, and a phlegm-dampening phlegm.

The composition includes a head flower bud, a berberine, a leachhin, a qi medicine, a cooling blood hemostasis, and a warming and dispelling medicine.

The composition includes a head flower bud, a berberine, a water-wetting agent, a qi medicine, a cooling blood hemostatic medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a water-wetting agent, a qi medicine, a cooling blood hemostatic medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a water-wetting agent, a qi medicine, a phlegm-dampening phlegm medicine, and a warm-yang dispersing medicine.

The composition includes a head flower bud, a berberine, a water-wetting agent, a qi medicine, a phlegm-dampening phlegm, and a digestive medicine.

The composition includes a head flower bud, a berberine, a leachhin, a qi medicine, a phlegm phlegm, and a remedy.

The composition includes a head flower bud, a berberine, a water-wetting agent, a qi medicine, a Wenyang cold medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a water-wetting agent, a qi medicine, a Wenyang cold medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a water permeable medicine, a qi medicine, a digestion medicine, and a solution medicine.

The composition includes a flower bud, a berberine, a leachhin, a phlegm, a blood stasis, a blood stasis and a hemostatic.

The composition includes a head flower bud, a berberine, a leachhin, a phlegm, a blood stasis, a phlegm and blood stasis.

The composition includes a head flower bud, a berberine, a water-wetting agent, a phlegm-removing medicine, a blood-activating phlegm medicine, and a warm-yang dispersing medicine.

The composition includes a flower bud, a berberine, a leachate, a phlegm, a blood stasis, and a digestive.

The composition includes a head flower bud, a berberine, a leachhin, a phlegm, a blood stasis, and a remedy.

The composition includes a head flower bud, a berberine, a water-wetting agent, a phlegm-receiving medicine, a cooling blood-stopping medicine, and a warm-yang dispersing medicine.

The composition includes a head flower bud, a berberine, a water-wetting agent, a phlegm-receiving medicine, a cooling blood-stopping medicine, and a digestive medicine.

The composition includes a head flower bud, a berberine, a water-wetting agent, a sputum medicine, a cooling blood hemostatic medicine, and a remedy medicine.

The composition includes a flower bud, a berberine, a leachhin, a phlegm, a phlegm, a phlegm and a phlegm.

The composition includes a flower bud, a berberine, a leachhin, a phlegm, a phlegm, and a digestive.

The composition includes a head flower bud, a berberine, a leachhin, a phlegm, a phlegm, and a remedy.

The composition includes a flower bud, a berberine, a leachhin, a sputum, a stagnation, a stagnation, and a digestive.

The composition includes a head flower bud, a berberine, a water-wetting agent, a phlegm-receiving agent, a warm-yang dispersing medicine, and a remedy.

The composition includes a head flower bud, a berberine, a water permeable medicine, a sputum medicine, a digestion medicine, and a remedy medicine.

The composition includes a flower bud, a berberine, a water-wetting agent, a blood-activating phlegm, a cooling blood-stopping drug, and a phlegm-dampening phlegm.

The composition includes a head flower bud, a berberine, a water-wetting drug, a blood-activating phlegm medicine, a cooling blood-stopping medicine, and a warm-yang dispersing medicine.

The composition includes a head flower bud, a berberine, a water-wetting agent, a blood-activating phlegm medicine, a cooling blood-stopping medicine, and a digestion-eliminating medicine.

The composition includes a head flower bud, a berberine, a water-wetting agent, a blood-activating phlegm medicine, a cooling blood-stopping medicine, and a solution-solving medicine.

The composition includes a head flower bud, a berberine, a water-wetting agent, a blood-activating phlegm medicine, a phlegm-dampening phlegm medicine, and a warm-yang dispersing medicine.

The composition includes a head flower bud, a berberine, a water-wetting agent, a blood-activating phlegm, a phlegm-relieving phlegm, and a digestive.

The composition includes a head flower bud, a berberine, a water-wetting agent, a blood-activating phlegm, a phlegm-dampening phlegm, and a remedy.

The composition includes a head flower bud, a berberine, a water-wetting agent, a blood-activating phlegm, a warm-yang dispersing medicine, and a digestive medicine.

The composition includes a head flower bud, a berberine, a water-wetting agent, a blood-activating phlegm, a warm-yang dispersing medicine, and a remedy.

The composition includes a head flower bud, a berberine, a water-wetting agent, a blood-activating phlegm, an anti-drug, and a solution.

The composition includes a flower bud, a berberine, a water-wetting drug, a blood-suppressing hemostatic agent, a phlegm-dampening phlegm, and a warm-yang dispersing medicine.

The composition includes a head flower bud, a berberine, a water-wetting agent, a cooling blood-stopping agent, a phlegm-dampening phlegm, and a digestive medicinal.

The composition includes a head flower bud, a berberine, a water-wetting drug, a cooling blood-stopping drug, a phlegm-dampening phlegm, and a remedy.

The composition includes a head flower bud, a berberine, a water-wetting agent, a cooling blood-stopping medicine, a warm-yang dispersing medicine, and a digestive medicine.

The composition includes a head flower bud, a berberine, a water-wetting agent, a cooling blood-stopping medicine, a warm-yang dispersing medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a water-wetting drug, a cooling blood-stopping drug, a digestion-eliminating drug, and a solution-solving drug.

The composition includes a head flower bud, a berberine, a water-wetting agent, a phlegm-dampening phlegm, a warm-yang dispersing medicine, and a digestive medicine.

The composition includes a head flower bud, a berberine, a water-wetting agent, a phlegm-dampening phlegm, a warming and dispelling medicine, and a remedy.

The composition includes a head flower bud, a berberine, a water-wetting agent, a phlegm-dampening phlegm, an anti-drug, and a remedy.

The composition includes a head flower bud, a berberine, a water-wetting agent, a warm-yang dispersing medicine, a digestive medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, and a phlegm phlegm medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, and a warm yang medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a sputum medicine, a cooling blood hemostatic medicine, and a phlegm and blood stasis medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a sputum medicine, a cooling blood hemostasis, and a warming and dispelling medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a sputum medicine, a cooling blood hemostatic medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a sputum medicine, a cooling blood hemostatic medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a phlegm medicine, a phlegm-dampening phlegm medicine, and a warm-yang dispersing medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a phlegm medicine, a phlegm phlegm medicine, and a food consuming medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a phlegm medicine, a phlegm phlegm medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a sputum medicine, a Wenyang cold medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a sputum medicine, a Wenyang cold medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a sputum medicine, a digestion medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a phlegm and blood stasis medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a blood circulation phlegm medicine, a cooling blood hemostasis medicine, and a warm and cold medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, and a solution medicine.

The composition includes the head flower bud, the berberine, the qi medicine, the blood circulation phlegm medicine, the phlegm and blood stasis medicine, and the warm yang medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a blood circulation phlegm medicine, a phlegm phlegm medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a blood circulation phlegm medicine, a phlegm phlegm medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a blood circulation phlegm medicine, a warm yang medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a blood circulation phlegm medicine, a Wenyang cold medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a blood circulation phlegm medicine, a digestion medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a cooling blood hemostasis, a phlegm and blood stasis medicine, and a warming and dispelling medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a cooling blood hemostasis, a phlegm and blood stasis medicine, and a digestive medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a cooling blood hemostasis, a phlegm and blood stasis medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a cooling blood hemostasis, a Wenyang cold medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a cooling blood hemostasis, a Wenyang cold medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a cooling blood hemostatic medicine, a digestion medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a phlegm-dampening phlegm, a warm-yang dispersing medicine, and a digestive medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a phlegm and blood stasis medicine, a Wenyang cold medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a qi medicine, a phlegm-dampening phlegm, an anti-drug, and a remedy.

The composition includes a head flower bud, a berberine, a qi medicine, a Wenyang cold medicine, a digestion medicine, and a prescription medicine.

The composition includes a flower bud, a berberine, a phlegm, a blood stasis, a blood stasis, a phlegm and blood stasis.

The composition includes a head flower bud, a berberine, a sputum medicinal herb, a blood circulation phlegm medicine, a cooling blood hemostatic drug, and a warming and dissipating cold medicine.

The composition includes a flower bud, a berberine, a sputum medicinal herb, a blood circulation phlegm medicine, a cooling blood hemostatic drug, and a digestion drug.

The composition includes a head flower bud, a berberine, a sputum medicinal herb, a blood circulation phlegm medicine, a cooling blood hemostatic drug, and a remedy drug.

The composition includes a flower bud, a berberine, a phlegm, a blood stasis, a phlegm, and a phlegm medicine.

The composition includes a flower bud, a berberine, a phlegm, a blood stasis, a phlegm, and a diarrhea.

The composition includes a flower bud, a berberine, a phlegm, a blood stasis, a phlegm, and a remedy.

The composition includes a flower bud, a berberine, a phlegm, a blood stasis, a warming and dispelling cold medicine, and a digestive medicine.

The composition includes a flower bud, a berberine, a phlegm, a blood stasis, a warming and dispelling medicine, and a remedy.

The composition includes a flower bud, a berberine, a phlegm, a blood stasis, a digestive, and a remedy.

The composition includes a flower bud, a berberine, a phlegm, a blood-suppressing hemostatic agent, a phlegm-dampening phlegm, and a warming and dispelling cold medicine.

The composition includes a head flower bud, a berberine, a phlegm, a blood-suppressing hemostatic agent, a phlegm-dampening phlegm, and a digestive.

The composition includes a flower bud, a berberine, a phlegm, a blood-suppressing hemostatic agent, a phlegm-dampening phlegm, and a remedy.

The composition includes a head flower bud, a berberine, a sputum medicinal medicine, a cooling blood stopping medicine, a warming and dispelling cold medicine, and a digestive medicine.

The composition includes a head flower bud, a berberine, a sputum medicine, a cooling blood hemostasis, a warming and dispelling medicine, and a remedy.

The composition includes a flower bud, a berberine, a phlegm, a blood-suppressing hemostatic, a digestive, and a remedy.

The composition includes a flower bud, a berberine, a phlegm, a phlegm, a phlegm, a phlegm, a phlegm, and a digestive.

The composition includes a flower bud, a berberine, a phlegm, a phlegm, a phlegm, a phlegm, and a remedy.

The composition includes a flower bud, a berberine, a phlegm, a phlegm, a phlegm, a drug, and a drug.

The composition includes a head flower bud, a berberine, a sputum medicinal medicine, a warming and dispelling medicine, a digestion medicine, and a remedy medicine.

The composition includes a flower bud, a berberine, a blood circulation phlegm, a blood circulation hemostasis, a phlegm and blood stasis medicine, and a warming and dispelling medicine.

The composition includes a head flower bud, a berberine, a blood circulation phlegm, a blood circulation hemostasis, a phlegm and blood stasis medicine, and a digestive medicine.

The composition includes a head flower bud, a berberine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a phlegm and blood stasis medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a blood circulation phlegm, a cooling blood hemostasis, a warming and dispelling cold medicine, and a digestive medicine.

The composition includes a head flower bud, a berberine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a Wenyang cold medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a digestion medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a blood circulation phlegm medicine, a phlegm-dampening phlegm medicine, a warm-yang dispersing medicine, and a digestion medicine.

The composition includes a flower bud, a berberine, a blood stasis phlegm, a phlegm phlegm, a phlegm medicine, and a remedy.

The composition includes a head flower bud, a berberine, a blood circulation phlegm, a phlegm phlegm, a digestion drug, and a remedy drug.

The composition includes a head flower bud, a berberine, a blood circulation phlegm medicine, a yangyang cold medicine, a digestion medicine, and a solution medicine.

The composition includes a flower bud, a berberine, a blood-suppressing hemostatic agent, a phlegm-dampening phlegm, a warming and dispelling cold medicine, and a digestive medicine.

The composition includes a flower bud, a berberine, a blood-suppressing hemostatic agent, a phlegm-dampening phlegm, a warming and dispelling medicine, and a remedy.

The composition includes a flower bud, a berberine, a blood-suppressing hemostatic agent, a phlegm-dampening phlegm, an anti-drug, and a remedy.

The composition includes a head flower bud, a berberine, a cooling blood hemostasis, a warming and dispelling medicine, a digestion medicine, and a solution medicine.

The composition includes a flower bud, a berberine, a phlegm, a phlegm, a phlegm, a phlegm, a remedy, a drug, and a remedy.

The composition is composed of a head bud, a berberine, and any four of the above eleven drugs in a pharmaceutical composition:

Preferred compositions include the head flower bud, berberine, heat-clearing medicine, tonic medicine, qi medicine, and blood-activating phlegm medicine selected from the group consisting of:

(1) 20-60 parts by weight of head flower, 2-6 parts by weight of berberine, 10-15 parts by weight of dandelion, 9-30 parts by weight of astragalus, 6-15 parts by weight of white peony, 2-6 parts by weight of licorice, ginseng 3 -9 parts by weight, 5-10 parts by weight of perilla stem, and 3-10 parts by weight of Corydalis.

Preferred compositions include the head flower bud, berberine, heat-clearing medicine, tonic medicine, phlegm-dampening phlegm medicine, and Wenyang chilling medicine selected from the group consisting of:

(1) 20-60 parts by weight of head flower, 2-6 parts by weight of berberine, 3-10 parts by weight of scutellaria, 3-9 parts by weight of ginseng, 2-6 parts by weight of licorice, 6-15 parts by weight of jujube, Pinellia 3-9 parts by weight, 3-10 parts by weight of dried ginger;

Preferred compositions include cep, berberine, tonic, diuretic, qi, and phlegm.

Further preferred compositions are selected from the group consisting of:

(1) 20-60 parts by weight of the head flower, 2-6 parts by weight of Rhizoma Coptidis, 9-18 parts by weight of Codonopsis pilosula, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, and 8-12 parts by weight of Schisandra chinensis;

(2) 20-60 parts by weight of the head flower, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, 8-12 parts by weight of Schisandra;

(3) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, 9-18 parts by weight of Codonopsis pilosula, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, and schisandra 8- 12 parts by weight.

The composition consists of the head flower bud, berberine, and any of the above nine drugs.

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, and a sputum medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting agent, a qi medicine, a blood circulation medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting agent, a qi medicine, and a cooling blood-stopping medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting agent, a qi medicine, and a phlegm-dampening medicine.

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, and a warm-yang medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a gas-making drug, and a digestion drug.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting agent, a phlegm-receiving medicine, a blood-activating phlegm medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a phlegm-receiving drug, and a cool blood-stopping Blood medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting agent, a phlegm-receiving medicine, and a phlegm-dampening phlegm.

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a phlegm-receiving drug, and a warm-yang dispersing drug.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a phlegm-receiving drug, and a digestive drug.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a phlegm-receiving drug, and a remedy drug.

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a blood-activating phlegm drug, and a cooling blood-stopping drug.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting agent, a blood-activating phlegm medicine, and a phlegm-dampening medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting agent, a blood-activating phlegm medicine, and a warm-yang medicine.

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-sparing osmotic drug, a blood-activating phlegm drug, and a digestion-eliminating drug.

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a blood-activating phlegm drug, and a remedy drug.

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a cooling blood-stopping drug, and a phlegm-dampening phlegm.

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a cooling blood-stopping drug, and a warm-yang dispersing drug.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a cooling blood-stopping drug, and a digestive drug.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a cooling blood-stopping drug, and a solution-solving drug.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting agent, a phlegm-dampening phlegm, and a warm-yang dispelling medicine.

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a phlegm-dampening phlegm, and a food-eliminating drug.

The composition includes a flower bud, a coptis, a heat-clearing drug, a tonic drug, a water-wetting drug, a phlegm-dampening phlegm, and a remedy.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting agent, a warm-yang dispersing medicine, and a digestive medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting agent, a warm-yang dispersing medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a digestion drug, and a drug solution.

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting agent, a qi medicine, a sputum medicine, and a blood-suppressing medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting agent, a qi medicine, a phlegm medicine, and a phlegm-dampening medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting agent, a qi medicine, a sputum medicine, and a warm-yang medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting agent, a qi medicine, a sputum medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a qi medicine, a sputum medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a qi medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting agent, a qi medicine, a blood circulation phlegm medicine, and a phlegm-dampening medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting agent, a qi medicine, a blood circulation phlegm medicine, and a warm-yang medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting agent, a qi medicine, a blood circulation phlegm medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting agent, a qi medicine, a blood circulation phlegm medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a qi medicine, a cooling blood hemostasis, and a phlegm-dampening phlegm.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting agent, a qi medicine, a cooling blood hemostasis, and a warm-yang dispersing medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting agent, a qi medicine, a cooling blood hemostatic medicine, and a digestive medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting agent, a qi medicine, a cooling blood hemostatic medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a qi medicine, a phlegm-dampening phlegm medicine, and a warm-yang dispersing medicine.

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, a qi medicine, a phlegm-dampening phlegm medicine, and a digestion-eliminating medicine.

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, a qi medicine, a phlegm-dampening phlegm, and a remedy.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting agent, a qi medicine, a Wenyang cold medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting agent, a qi medicine, a Wenyang cold medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, a qi medicine, a digestion medicine, and a solution medicine.

The composition is composed of a flower bud, a berberine, and any five of the above eleven drugs in a pharmaceutical composition:

Preferred compositions include the head flower bud, berberine, tonic medicine, diarrhea phlegm, qi medicine, blood circulation phlegm medicine, phlegm and blood stasis medicine.

Further preferred compositions are selected from the group consisting of:

(1) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, 3-10 parts by weight of Corydalis, and Pinellia ternata 3 -9 parts by weight;

(2) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, 9-18 parts by weight of Codonopsis pilosula, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, 10-15 parts by weight of Salvia miltiorrhiza, and Magnolia 3 - 10 parts by weight.

Preferred compositions include head flower buds, berberine, heat-clearing drugs, tonics, water-wetting drugs, qi medicines, blood-activating phlegm drugs, and remedies.

Further preferred compositions are selected from the group consisting of:

(1) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, 3-10 parts by weight of Corydalis, cassia twig 3 -10 parts by weight;

(2) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, 9-18 parts by weight of Codonopsis pilosula, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, 10-15 parts by weight of Salvia miltiorrhiza, Bupleurum 3 - 10 parts by weight.

The composition consists of the head bud, berberine, and any of the above-mentioned eleven classes of drugs.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting agent, a qi medicine, a phlegm medicine, and a blood-suppressing medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting agent, a qi medicine, a phlegm medicine, and a phlegm-dampening medicine.

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a sputum medicine, and a warm-yang medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a sputum medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a sputum medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a blood-activating phlegm medicine, and a cooling blood-stopping medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting agent, a qi medicine, a blood-activating phlegm medicine, and a phlegm-dampening medicine.

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a blood-activating phlegm medicine, and a warm-yang dispersing medicine.

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi-drug, a blood-activating phlegm, and a food-eliminating drug.

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a blood-activating phlegm medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting agent, a qi medicine, a cooling blood-stopping medicine, and a phlegm-dampening medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting agent, a qi medicine, a cooling blood-stopping medicine, and a warm-yang medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a cooling blood hemostatic medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a cooling blood hemostatic medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a phlegm-dampening phlegm medicine, and a warm-yang dispersing medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting agent, a qi medicine, a phlegm-dampening phlegm medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, and a phlegm Peony and solution.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting agent, a qi medicine, a Wenyang cold medicine, and a digestion medicine.

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a warm-yang dispersing medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a digestion drug, and a solution medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, and a phlegm-dampness phlegm medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, and a warm-yang medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, and a remedy medicine.

The composition includes a head flower bud, a coptis, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood-suppressing medicine, and a phlegm-dampening medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood-suppressing medicine, and a warm-yang medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a cooling blood hemostasis medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a cooling blood hemostatic medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a phlegm medicine, a phlegm-dampening phlegm medicine, and a warm-yang medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting agent, a qi medicine, a phlegm medicine, a phlegm-dampening phlegm medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a phlegm medicine, a phlegm-dampening phlegm medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, a qi medicine, a sputum medicine, a warm-yang dispersing medicine, and a digestive medicine.

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a qi medicine, a sputum medicine, a warm-yang dispersing medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting agent, a qi medicine, a sputum medicine, a digestion medicine, and a remedy medicine.

The composition is composed of a medicinal composition of the first six classes of drugs, such as scutellaria, berberine, and the above eleven types of medicinal properties:

Preferred compositions include the head flower bud, the berberine, the tonic medicine, the water-wetting drug, the qi medicine, the phlegm medicine, the warm-yang powder medicine, and the solution medicine.

Further preferred compositions are selected from the group consisting of:

(1) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, 9-18 parts by weight of Codonopsis pilosula, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, 8-12 parts by weight of Schisandra chinensis, Wujing 2- 5 parts by weight, Bupleurum 3-10 parts by weight;

(2) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, 8-12 parts by weight of schisandra, galangal 3 -6 parts by weight, 3-10 parts by weight of cassia twig;

The composition consists of the head flower bud, berberine, and any of the above seven drugs.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, and a cooling blood hemostatic medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, and a phlegm-dampness phlegm medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood-activating phlegm medicine, and a warm-yang medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a cooling blood-stopping medicine, and a warm-yang medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a cooling blood hemostatic medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a sputum medicine, a cooling blood hemostatic medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a phlegm medicine, a phlegm-dampening phlegm medicine, and a warm-yang medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a phlegm medicine, a phlegm-dampening phlegm medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a phlegm medicine, a phlegm-dampening phlegm medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a warm-yang powder medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a phlegm medicine, a Wenyang cold medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting agent, a gas medicine, a sputum medicine, a digestion medicine, and a medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostasis medicine, and a phlegm-dampening medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostasis medicine, and a Wenyang cold medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a phlegm-dampening phlegm medicine, and a warm-yang medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a phlegm-dampening phlegm medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a phlegm-dampening phlegm medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a warm-yang medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a warm-yang powder medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting agent, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a digestion medicine, and a remedy medicine.

The composition is composed of a medicinal composition of the genus, berberine, and any of the eleven types of drugs mentioned above:

Preferred compositions include head flower bud, berberine, tonic medicine, water-wetting drug, qi medicine, phlegm medicine, blood-activating phlegm medicine, phlegm-dampening phlegm medicine, and warm-yang dispersing medicine.

Further preferred compositions are selected from the group consisting of:

(1) 20-60 parts by weight of head flower buds, 2-6 parts by weight of Rhizoma coptidis, 9-18 parts by weight of Codonopsis pilosula, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, 8-12 parts by weight of Schisandra, Corydalis 3- 10 parts by weight, 3-9 parts by weight of Pinellia, 2-5 parts by weight of Wusong;

(2) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, 8-12 parts by weight of schisandra, and 10 parts by weight of Salvia miltiorrhiza 15 parts by weight, Magnolia 3-10 parts by weight, Galangal 3-6 parts by weight;

The composition consists of the first eight types of drugs, such as the head bud, the berberine, and the above eleventh medicinal properties.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a phlegm-removing medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, and a phlegm-dampening medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-sparing osmotic medicine, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostasis medicine, and a Wenyang cold medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, Promote blood circulation to remove phlegm, cool blood to stop bleeding drugs, digestion drugs.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, and a remedy medicine.

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a phlegm-removing medicine, a blood-activating phlegm medicine, a phlegm-dampening phlegm medicine, and a warm-yang dispersing medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a phlegm-dampening phlegm medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a phlegm-removing medicine, a blood-activating phlegm medicine, a phlegm-dampening phlegm medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a phlegm-removing medicine, a blood-activating phlegm medicine, a warm-yang dispersing medicine, and a digestive medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood-activating phlegm medicine, a warm-yang medicine, and a medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a digestion medicine, and a remedy medicine.

The composition includes the head flower bud, the berberine, the tonic medicine, the diarrhea medicine, the qi medicine, the phlegm medicine, the blood circulation phlegm medicine, the cooling blood hemostasis medicine, the phlegm and blood stasis medicine, the Wenyang cold medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a phlegm-dampening phlegm medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a phlegm-dampening phlegm medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a Wenyang cold medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a Wenyang cold medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a digestion medicine, and a solution medicine.

The composition is composed of a medicinal composition of the genus, berberine, and any of the above-mentioned eleven types of medicinal properties:

Preferred compositions include head flower buds, berberine, tonic medicine, diarrhea phlegm, qi medicine, phlegm medicine, blood circulation phlegm, blood circulation hemostasis, phlegm and blood stasis medicine, and warming medicine.

Further preferred compositions are selected from the group consisting of:

(1) 20-60 parts by weight of head flower buds, 2-6 parts by weight of Rhizoma coptidis, 9-18 parts by weight of Codonopsis pilosula, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, 8-12 parts by weight of Schisandra, Corydalis 3- 10 parts by weight, white and 6-15 parts by weight, 3-9 parts by weight of Pinellia, and 2-5 parts by weight of Wusong;

(2) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, 8-12 parts by weight of schisandra, and 10 parts by weight of Salvia miltiorrhiza 15 parts by weight, white and 6-15 parts by weight, Magnolia 3-10 parts by weight, Galangal 3-6 parts by weight;

The composition consists of the head bud, berberine, and any of the nine drugs listed above.

The composition includes a head flower bud, a berberine, a leachhin, a qi medicine, a sputum medicinal medicine, a blood circulation phlegm medicine, a blood circulation hemostasis medicine, a phlegm and blood stasis medicine, a yangyang cold medicine, a digestion medicine, Solution medicine.

The composition includes the head flower bud, berberine, tonic medicine, qi medicine, phlegm medicine, blood circulation phlegm medicine, cooling blood hemostasis medicine, phlegm and blood stasis medicine, Wenyang cold medicine, digestion medicine, solution table medicine.

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a phlegm-removing drug, a blood-activating phlegm drug, a cooling blood-stopping medicinal agent, a phlegm-dampening phlegm drug, a yang-yang medicinal drug, a digestion drug, and a solution. Table medicine.

The composition includes the head flower bud, berberine, tonic medicine, diarrhea dialysis medicine, qi medicine, blood circulation phlegm medicine, cooling blood hemostasis medicine, phlegm and blood stasis medicine, Wenyang cold medicine, digestion medicine, solution Table medicine.

The composition includes the head flower bud, berberine, tonic medicine, diarrhea phlegm, qi medicine, phlegm medicine, cooling blood to stop bleeding medicine, phlegm and blood stasis medicine, Wenyang cold medicine, digestion medicine, solution table medicine.

The composition includes the head flower bud, berberine, tonic medicine, diarrhea phlegm, qi medicine, phlegm medicine, blood circulation phlegm medicine, phlegm and blood stasis medicine, Wenyang cold medicine, digestion medicine, solution table medicine.

The composition includes the head flower bud, berberine, tonic medicine, diarrhea phlegm, qi medicine, phlegm medicine, blood circulation phlegm medicine, cooling blood hemostasis medicine, Wenyang cold medicine, digestion medicine, solution medicine .

The composition includes the head flower bud, berberine, tonic medicine, diarrhea phlegm, qi medicine, phlegm medicine, blood circulation phlegm medicine, cooling blood hemostasis medicine, phlegm and blood stasis medicine, digestion medicine, solution medicine .

The composition includes a head flower bud, a beryl, a tonifying agent, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a phlegm-dampening phlegm medicine, a yang yang medicine, Solution medicine.

The composition includes a head flower bud, a beryl, a tonifying agent, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a phlegm-dampening phlegm medicine, a yang yang medicine, Digestive medicine.

The composition includes the head flower bud, berberine, heat-clearing medicine, qi medicine, phlegm medicine, blood circulation phlegm medicine, cooling blood hemostasis medicine, phlegm and blood stasis medicine, Wenyang cold medicine, digestion medicine, solution Table medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a phlegm-removing drug, a blood-activating phlegm drug, a cooling blood-stopping medicinal agent, a phlegm-dampening phlegm drug, a warm-yang dispelling medicinal agent, a digestive medicinal drug, Solution medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a water-wetting drug, a qi medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, a warm-yang dispersing medicine, a digestion medicine, Solution medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a qi medicine, a sputum medicine, a blood-suppressing blood-suppressing medicine, a phlegm-dampening phlegm medicine, a warm-yang dispersing medicine, a digestion medicine, and a solution. Table medicine.

The composition includes a flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a qi medicine, a phlegm-removing medicine, a blood-activating phlegm medicine, a phlegm-dampening phlegm medicine, a warm-yang dispersing medicine, a digestion medicine, and a solution. Table medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a qi medicine, a sputum medicinal medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a warm-yang dispersing medicine, a digestion medicine, and a solution table. medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a phlegm-dampening phlegm medicine, a digestion medicine, and a solution table. medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a qi medicine, a sputum medicinal medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, and a warm-yang dispersing medicine. , to solve the drug.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a qi medicine, a sputum medicinal medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, and a warm-yang dispersing medicine. , digestion drugs.

The composition includes a flower bud, a peony root, a heat-clearing drug, a tonic drug, a phlegm-removing drug, a blood-activating phlegm drug, a cooling blood-stopping medicinal agent, a phlegm-dampening phlegm drug, a yang-yang medicinal drug, a food-disinfecting drug, and a solution table. medicine.

The composition includes the head flower bud, berberine, heat-clearing medicine, tonic medicine, qi medicine, blood circulation phlegm medicine, cooling blood hemostasis medicine, phlegm and blood stasis medicine, Wenyang cold medicine, digestion medicine, solution table medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a qi medicine, a sputum medicine, a cooling blood hemostasis medicine, a phlegm-dampening phlegm medicine, a Wenyang cold medicine, a digestion medicine, and a remedy medicine. .

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a phlegm-dampening phlegm medicine, a warm-yang dispersing medicine, a digestion medicine, and a remedy medicine. .

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a Wenyang cold medicine, a digestion medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a phlegm-dampening phlegm medicine, a digestion medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a phlegm-dampening phlegm medicine, a yang-yang medicine, a solution Table medicine.

The composition includes the head flower bud, berberine, heat-clearing medicine, tonic medicine, qi medicine, phlegm medicine, blood circulation phlegm medicine, cooling blood hemostatic medicine, phlegm and blood stasis medicine, Wenyang cold medicine, digestion medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, a warm-yang dispersing medicine, a digestion medicine, and a solution. Table medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a phlegm-receiving medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, a warm-yang dispersing medicine, a digestion medicine, and a solution table. medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a phlegm-removing drug, a blood-activating phlegm drug, a phlegm-dampening phlegm drug, a warm-yang dispersing drug, a digestion drug, and a solution table. medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a phlegm-removing drug, a blood-activating phlegm drug, a cooling blood-stopping drug, a warm-yang dispersing drug, a digestive drug, and a remedy drug. .

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a phlegm-removing medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, a digestion medicine, and a remedy medicine. .

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a phlegm-removing medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, a warm-yang dispersing medicine, Solution medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a phlegm-removing medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, a warm-yang dispersing medicine, Digestive medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, a warm-yang dispersing medicine, a digestion medicine, and a solution table. medicine.

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi-drug, a blood-activating phlegm, a phlegm-dampening phlegm, a yang-yang medicinal agent, a digestion-preventing drug, and a solution. medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a warm-yang dispersing medicine, a digestion medicine, and a solution medicine. .

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, a digestion medicine, and a remedy medicine. .

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a blood circulation Peony, cooling blood to stop bleeding, phlegm and blood stasis, Wenyang cold medicine, solution medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, a warm-yang dispelling medicine, Digestive medicine.

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a phlegm-receiving medicinal agent, a phlegm-dampening phlegm drug, a yang-yang medicinal drug, a digestive medicinal drug, and a remedy drug. .

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a cooling blood-stopping medicine, a Wenyang cold medicine, a digestion medicine, and a solution medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, a digestion medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, a warm-yang dispelling medicine, and a solution. Table medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, a warm-yang dispersing medicine, and a digestion. medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood-activating phlegm medicine, a warm-yang powder medicine, a digestion medicine, and a medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a phlegm-dampening phlegm medicine, a digestion medicine, and a remedy medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a phlegm-removing medicine, a blood-activating phlegm medicine, a phlegm-dampening phlegm medicine, a warm-yang dispelling medicine, and a solution. Table medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood-activating phlegm medicine, a phlegm-dampening phlegm medicine, a warm-yang dispersing medicine, and a digestion medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a digestion medicine, and a remedy medicine.

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a phlegm-removing medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a warm-yang dispersing medicine, and a solution table. medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a warm-yang medicine, and a food-eliminating medicine. .

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a phlegm-removing medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, and a solution table. medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, a digestion medicine. .

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, and a yang-yang Dispel cold medicine.

The composition is composed of a head bud, a berberine, and any of the above nine drugs in a pharmaceutical composition:

Preferred compositions include head flower bud, berberine, heat-clearing medicine, tonic medicine, water-wetting drug, qi medicine, phlegm medicine, blood-activating phlegm medicine, cooling blood-stopping medicine, phlegm-dampening phlegm medicine, Wenyang powder Cold medicine, solution medicine.

Further preferred compositions are selected from the group consisting of:

(1) 20-60 parts by weight of the head flower, 2-6 parts by weight of berberine, 9-18 parts by weight of Codonopsis pilosula, 9-15 parts by weight of 茯苓, Chen 5-10 parts by weight of skin, 8-12 parts by weight of Schisandra, 3-10 parts by weight of Corydalis, 6-15 parts by weight of white, 3-9 parts by weight of Pinellia, 2-5 parts by weight of Wusong, 3-10 parts by weight of Bupleurum Share

(2) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, 8-12 parts by weight of schisandra, and 10 parts by weight of Salvia miltiorrhiza 15 parts by weight, white and 6-15 parts by weight, Magnolia 3-10 parts by weight, Galangal 3-6 parts by weight, Guizhi 3-10 parts by weight;

The composition consists of the head flower bud, berberine, and any of the eleven types of drugs mentioned above.

The composition includes a head flower bud, a beryl, a tonifying agent, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a phlegm-dampening phlegm medicine, a yang yang medicine, Digestive medicine, solution medicine.

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a qi medicine, a sputum medicinal medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, and a warm-yang dispersing medicine. , digestion drugs, solution drugs.

The composition includes the head flower bud, berberine, heat-clearing medicine, tonic medicine, qi medicine, phlegm medicine, blood circulation phlegm medicine, cooling blood hemostatic medicine, phlegm and blood stasis medicine, Wenyang cold medicine, digestion Medicine, solution medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a phlegm-removing medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, a warm-yang dispersing medicine, Digestive medicine, solution medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, a warm-yang dispelling medicine, Digestive medicine, solution medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, a warm-yang dispersing medicine, and a digestion. Medicine, solution medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood-activating phlegm medicine, a phlegm-dampening phlegm medicine, a warm-yang dispersing medicine, and a digestion Medicine, solution medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a warm-yang medicine, and a food-eliminating medicine. , to solve the drug.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, a digestion medicine. , to solve the drug.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, and a yang-yang Dispel cold medicine, solution medicine.

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, and a yang-yang Dispel cold medicine, digestion medicine.

The composition consists of a medicinal composition of the genus, berberine, and any of the eleven classes of drugs mentioned above:

Preferred compositions include head flower bud, berberine, tonic medicine, diarrhea phlegm, qi medicine, phlegm medicine, blood circulation phlegm medicine, cooling blood hemostatic medicine, phlegm and blood stasis medicine, Wenyang cold medicine, digestion The group of medicines is selected from any of the following groups:

(1) 20-60 parts by weight of head flower buds, 2-6 parts by weight of Rhizoma coptidis, 9-18 parts by weight of Codonopsis pilosula, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, 8-12 parts by weight of Schisandra, Corydalis 3- 10 parts by weight, white and 6-15 parts by weight, 3-9 parts by weight of Pinellia, 2-5 parts by weight of Evodia, 9-12 parts by weight of Hawthorn;

(2) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, 8-12 parts by weight of schisandra, and 10 parts by weight of Salvia miltiorrhiza 15 parts by weight, white and 6-15 parts by weight, magnolia 3-10 weight The amount is 3-6 parts by weight of galangal and 9-12 parts by weight of hawthorn.

Preferred compositions include the head flower bud, berberine, tonic medicine, diarrhea phlegm, qi medicine, phlegm medicine, blood circulation phlegm medicine, cooling blood hemostatic medicine, Wenyang cold medicine, digestion medicine, solution medicine Groups are selected from any of the following groups:

(1) 20-60 parts by weight of head flower buds, 2-6 parts by weight of Rhizoma coptidis, 9-18 parts by weight of Codonopsis pilosula, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, 8-12 parts by weight of Schisandra, Corydalis 3- 10 parts by weight, white and 6-15 parts by weight, 2-5 parts by weight of Evodia, 9-12 parts by weight of hawthorn, 3-10 parts by weight of Bupleurum;

(2) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, 8-12 parts by weight of schisandra, and 10 parts by weight of Salvia miltiorrhiza 15 parts by weight, white and 6-15 parts by weight, galangal 3-6 parts by weight, hawthorn 9-12 parts by weight, and cassia twig 3-10 parts by weight.

The composition consists of any of eleven drugs of the above ten medicinal properties.

The composition is composed of a medicinal composition of the eleventh medicinal herb, a berberine, and any eleven drugs of the above-mentioned eleven types of medicinal properties:

Preferred compositions include head flower bud, berberine, tonic medicine, diarrhea phlegm, qi medicine, phlegm medicine, blood circulation phlegm medicine, cooling blood hemostatic medicine, phlegm and blood stasis medicine, Wenyang cold medicine, digestion Medicine, solution medicine.

Further preferred compositions are selected from the group consisting of:

(1) 20-60 parts by weight of head flower buds, 2-6 parts by weight of Rhizoma coptidis, 9-18 parts by weight of Codonopsis pilosula, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, 8-12 parts by weight of Schisandra, Corydalis 3- 10 parts by weight, white and 6-15 parts by weight, 3-9 parts by weight of Pinellia, 2-5 parts by weight of Evodia, 9-12 parts by weight of hawthorn, 3-10 parts by weight of Bupleurum;

(2) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, 8-12 parts by weight of schisandra, and 10 parts by weight of Salvia miltiorrhiza 15 parts by weight, white and 6-15 parts by weight, Magnolia 3-10 parts by weight, Galangal 3-6 parts by weight, Hawthorn 9-12 parts by weight, and Guizhi 3-10 parts by weight.

The pharmaceutical composition according to the first aspect of the present invention, characterized in that the composition is obtained by extracting the head flower buds and other medicinal materials with an inorganic or organic solvent alone or in a mixed solvent.

The pharmaceutical composition according to the first aspect of the present invention, characterized in that the composition is obtained by extracting and mixing the head flower buds and other medicinal materials with two or more mixed solvents of water and ethanol, acetone, and ethyl acetate.

A pharmaceutical composition according to the first aspect of the present invention, characterized in that the composition is obtained by extracting 5-30 times of water from the head flower and other herbs.

The pharmaceutical composition according to the first aspect of the present invention, characterized in that the composition is obtained by extracting 5-30 times of a 30-100% organic solution of the head flower buds and other medicinal materials.

The pharmaceutical composition according to the first aspect of the present invention, characterized in that the composition is extracted from 5-30 times of 30-99% of lower alcohol (C1-C5), acetone, acetic acid solution by head flower buds and other medicinal materials. And get.

The pharmaceutical composition according to the first aspect of the present invention, characterized in that the composition is obtained by extracting 5-30 times of a 30-99% aqueous solution of ethanol as an extraction solvent. In one embodiment, the aqueous ethanol solution is preferably a 70% ethanol solution, and the solution is selected to be 6-8 times.

The pharmaceutical composition according to the first aspect of the present invention, characterized in that the composition is obtained by extracting and mixing 5-15 times of a mixed solution of an alcohol and an ester of 5-95% of an anthraquinone and other medicinal materials.

The pharmaceutical composition according to the first aspect of the present invention, characterized in that the composition is obtained by extracting and extracting 5-15 times of a mixed solution of 5-95% ethanol and ethyl acetate as an extraction solvent. .

The pharmaceutical composition according to the first aspect of the present invention, characterized in that the composition is obtained by extracting 5 to 20 times of ethyl acetate, petroleum ether and diethyl ether from the head flower and other herbs.

The pharmaceutical composition according to the first aspect of the present invention, wherein the composition is prepared according to the method comprising the steps of: 5 to 30 times (e.g., 5 to 15 times, for example, 6 to 12) of the medicinal material constituting the composition. (water), water, ethanol, ethanol aqueous solution decoction and / or reflux extraction 1 to 5 times (for example, 2 to 3 times), each 0.5 to 5 hours (for example, 0.5 to 3 hours, for example, 1 to 3 hours), filtered and The filtrate was concentrated and dried.

The pharmaceutical composition according to the first aspect of the present invention, wherein the composition is prepared according to the method comprising the steps of: taking a medicinal material constituting the composition, adding 5 to 30 times (for example, 5 to 15 times, for example, 6 to 12 times) water is decoctioned at 50-100 ° C for 1 to 5 times (for example, 2 to 3 times), 0.5 to 5 hours each time (for example, 0.5 to 3 hours, for example, 1 to 3 hours), filtered and combined The extract is concentrated to a thick paste having a relative density of 1.1 to 1.5 (for example, 1.2 to 1.4), and dried under reduced pressure.

The pharmaceutical composition according to the first aspect of the present invention, wherein the composition is prepared according to the method comprising the steps of: taking a medicinal material constituting the composition, adding 5 to 30 times (for example, 5 to 15 times, for example, 6 to 12 times) 30-99% ethanol aqueous solution is refluxed for 1 to 5 times (for example, 2 to 3 times) for 0.5 to 5 hours each time (for example, 0.5 to 3 hours, for example, 1 to 3 hours), and the extracts are filtered and combined. It is concentrated to a thick paste having a relative density of 1.1 to 1.5 (for example, 1.2 to 1.4) at 60 to 90 ° C (for example, 65 to 75 ° C), and dried under reduced pressure.

The above pharmaceutical composition further comprises one or more other drugs selected from the group consisting of: an antimicrobial agent, a proton pump inhibitor, a gastric mucosal protective agent, an antacid, and an H ₂ receptor antagonist.

Preferred antimicrobial agents include, but are not limited to, penicillins such as amoxicillin, macrolides such as clarithromycin, and nitrazoles such as metronidazole.

Preferred proton pump inhibitors include, but are not limited to, omeprazole, lansoprazole, pantoprazole

Preferred gastric mucosal protective agents include, but are not limited to, sucralfate, smecta

Preferred antacids, such as aluminum hydroxide magnesium

Preferred H ₂ receptor antagonists, such as cimetidine, ranitidine, famotidine.

The invention also discloses a method for preparing a pharmaceutical composition extract, characterized in that the step of the method is selected from any one or more of the following:

(1-1) being extracted by an inorganic or organic solvent alone or in a mixed solvent;

(1-2) extracting and obtaining two kinds of mixed solvents of water, ethanol, acetone and ethyl acetate;

(1-3) using 5 to 30 times of water for solvent extraction and obtaining;

(1-4) 5-30 times of 30-99% of lower alcohol (C1-C5), acetone, acetic acid solution is extracted and obtained;

(1-5) 5 to 30 times of a 30 to 99% aqueous solution of ethanol as an extraction solvent and obtained by extraction;

(1-6) 6 to 8 times of a 70% aqueous solution of ethanol as a solvent extraction and obtained;

(1-7) is obtained by extracting and obtaining 5 to 15 times of a mixed solvent of 5 to 95% of an alcohol and an ester;

(1-8) 5 to 20 times of ethyl acetate, petroleum ether, diethyl ether as an extraction solvent and obtained by extraction;

(2) Prepared according to the method comprising the steps of: decocting the medicinal material constituting the composition with water, ethanol, ethanol solution and/or refluxing, filtering and concentrating the filtrate, and drying;

(3) Prepared according to the method comprising the following steps: weigh the medicinal materials constituting the composition, add 5 to 30 times of water to cook, extract 1 to 5 times at 50 to 100 ° C, 0.5 to 5 hours each time, filter and combine to extract The liquid is concentrated to a thick paste having a relative density of 1.1 to 1.5, and dried under reduced pressure;

(4) Prepared according to the method comprising the following steps: weigh the medicinal materials constituting the composition, add 6-8 times of water to decoct, extract 2 times at 85-100 ° C, each time for 1 to 1.5 hours, filter and combine the extracts, Concentrated to a thick paste having a relative density of 1.2 to 1.3, dried under reduced pressure, that is;

(5) Prepared according to the method comprising the following steps: weigh the medicinal material constituting the flower bud composition, and add 5 to 30 times of ethanol and 30 to 99% ethanol aqueous solution to reflux for 1 to 5 times, each time 0.5 to 5 hours, The extract is filtered and combined, concentrated to a thick paste having a relative density of 1.1 to 1.5, and dried under reduced pressure;

(6) Prepared according to the method comprising the following steps: weighing the medicinal material constituting the flower bud composition, adding 6 to 8 times of 70% ethanol aqueous solution to extract twice, each time for 1 to 1.5 hours, filtering and combining the extracts, It is concentrated to a thick paste having a relative density of 1.2 to 1.3, and dried under reduced pressure.

The invention includes all of the pharmaceutical composition extracts prepared by the above methods.

A second aspect of the invention provides a pharmaceutical formulation composition.

For ease of use, the compositions of the present invention further comprise one or more non-toxic physiologically acceptable carriers. The acceptable carriers include any excipients known in the art and excipients that function as controlled release. Commonly used excipients include diluents, binders, wetting agents, disintegrants, lubricants, glidants, porogens, plasticizers, fillers, solubilizers, and emulsifiers. The diluent may be, but not limited to, starch, dextrin, sucrose, glucose, lactose, mannitol, sorbitol, xylitol, microcrystalline cellulose, calcium sulfate, calcium hydrogen phosphate, calcium carbonate, etc.; the humectant may be but not Limited to water, ethanol, isopropanol, etc.; the binder may be starch slurry, dextrin, syrup, honey, glucose solution, microcrystalline cellulose, gum arabic, gelatin pulp, sodium carboxymethyl cellulose, methyl fiber , hydroxypropyl methylcellulose, ethyl cellulose, acrylic resin, carbomer, polyvinylpyrrolidone, polyethylene glycol, etc.; disintegrants can be, but are not limited to, dry starch, microcrystalline cellulose, low substitution Hydroxypropyl cellulose, cross-linked polyvinylpyrrolidone, croscarmellose sodium, sodium carboxymethyl starch, sodium hydrogencarbonate and citric acid, polyoxyethylene sorbitan fatty acid ester, dodecyl sulfonate Sodium or the like; the lubricant and the glidant may be, but not limited to, talc, silica, stearate, tartaric acid, liquid paraffin, polyethylene glycol; the solubilizer and emulsifier may be, but not limited to, ethanol, different Propanol, ethyl carbonate, ethyl acetate, Alcohol, benzyl benzoate, propylene glycol, 1,3-butylene glycol, dimethylformamide, oils (especially cottonseed oil, peanut oil, corn oil, germ oil, olive oil, castor oil and sesame oil), glycerin, Fatty acid esters of tetrahydrofuranol, polyethylene glycol, and sorbitan, and mixtures thereof. The excipient that acts to slow release is selected from one or more of a hydrophilic gel material, a waxy material, and an insoluble material. The hydrophilic gel material may be selected from the group consisting of hydroxypropylmethylcellulose, carbopol, sodium carboxymethylcellulose and alginate, and the waxy lipid material may be selected from the group consisting of cetyl alcohol and ten. The octa alcohol, beeswax, glyceryl behenate, stearic acid and carnauba wax, the insoluble material may be selected from the group consisting of ethyl cellulose, acrylic resin, polyoxyethylene and polyethylene.

In addition, coloring agents, preservatives, perfumes, flavoring agents or other additives may also be added to the pharmaceutical preparations as needed.

To this end, the invention also relates to formulations comprising a pharmaceutical composition and a pharmaceutically acceptable carrier. Any dosage form suitable for human or animal use can be prepared by combining the composition with one or more pharmaceutically acceptable solid or liquid excipients and/or adjuvants. The formulation can be prepared according to methods well known in the art. The composition of the present invention is usually contained in a pharmaceutical preparation in an amount of 6 to 12 g.

The pharmaceutical preparation of the present invention is preferably an oral preparation for the purpose of administration and enhancing the therapeutic effect.

Oral preparation prepared by the pharmaceutical composition of the present invention includes granules, tablets, pills, capsules, oral liquid preparations And related sustained-release preparations and sustained-release preparations, the sustained-release preparations include skeletal type, membrane-controlled type, osmotic pump type, gastric retention type sustained release controlled release preparation, microcapsules, nanoparticles, lipids The drug is a new carrier sustained-release controlled release preparation, and the gastric retention-type sustained-release preparation is preferably a gastric floating agent.

Taking a gastric floating agent as an example, the preparation process of the preparation is as follows:

The raw material was 31% of the composition, 31% of the IV acrylic resin, 31% of stearyl alcohol, 7% of MCC101, and an appropriate amount of magnesium stearate was added, and the film was directly compressed by a dry method to obtain a floating tablet of the first calyx composition.

A third aspect of the invention provides the use of a pharmaceutical composition for the preparation of an antibacterial agent.

The use according to the second aspect of the present invention is characterized in that the pathogen is selected from the group consisting of Gram-positive methicillin-resistant Staphylococcus aureus S. aureus (Methicllin-resistant, MRSA), methicillin-sensitive golden yellow Staphylococcus epidermidis (MRSE), methicillin-sensitive Staphylococcus epidermidis (MSSE), also selected from Gram-negative bacteria large intestine ESBLS Escherichia Coli, Eco ⁺ , Escherichia coli (non-ESBLS) Escherichia Coli, Eco ^- , Klebsiella Klebsiella (ESBLs) K. penumonia, KPN ⁺ , Klebsiella pneumonia (non-ESBLs) K. penumonia , Pseudomonas aeruginosa (PAE), Helicobacter pylori.

In the present invention, the term "extraction" may be impregnation at normal temperature, or extraction at elevated temperatures (e.g., boiling and/or reflux), or a combination of these modes of operation. It may further comprise further processing the extract, such as further purification, such as solvent removal, precipitation removal impurities, solvent extraction, resin adsorption separation, and the like.

As described herein, the term "extract" will include extracts of any purity that can be used to achieve any of the objectives of the invention, and the extraction purity of the extract can vary over a wide range.

The invention has the beneficial effects that the composition improves the single anti-Helicobacter pylori activity of the head flower bud, and the minimum antibacterial requirement of the water extract composition A for Hp ATCC700392 is 9.84 mg/ml, and the crude drug content of berberine is 0.98mg/ml, lower than the requirement of unilateral calyx unilateral (36.68mg/ml) and berberine unilateral (1.37mg/ml), enhancing the antibacterial synergistic effect between the head flower bud and the berberine; alcohol extracting composition A, composition B. The minimum antibacterial requirement of the composition C to Hp ATCC700392 is 3.63, 19.48, 17.16 (mg/ml), which is lower than the requirement of the first flower (40.44 mg/ml); The minimum antibacterial requirement of the composition A, the composition B and the composition C for Hp SS1 was 3.63, 2.44, 2.15 (mg/ml), respectively, which was lower than that of the head flower (5.06 mg/ml). The required content; the minimum antibacterial requirement of the alcohol extracting composition B for the metronidazole-resistant strain is 4.87 mg/ml, which is lower than that required for the single flower (10.11 mg/ml).

The composition has good antibacterial activity. The minimum antibacterial crude drug content of the water extracting composition A against Gram-positive bacteria was <0.082 mg/ml, and the crude drug content of Rhizoma Coptidis and the head flower buds were 0.204 and 0.621 mg/ml, respectively; the lowest against Gram-negative bacteria The crude drug content of the bacteria was <0.0824 mg/ml, and the crude drug content of the berberine unilateral and the head flower buds were 0.204 and 5.175 mg/ml, respectively.

DRAWINGS

Figure 1 shows the results of clinical drug-resistant strain verification.

Figure 2 shows the results of in vitro inhibition of the composition against H. pylori.

detailed description

The above content of the present invention will be further described in detail below by way of specific embodiments in the form of embodiments. However, the scope of the above-mentioned subject matter of the present invention should not be construed as being limited to the following embodiments. Any technique implemented based on the above description of the present invention is within the scope of the present invention.

Example

Example 1 : Preparation of Composition A Alcohol Extract Powder ()

Weigh 1350g of head flower buds, 135g of fried berberine, 270g of licorice, wash, add 8 times of 70% ethanol and reflux in water bath for 1.5 hours, filter; add 6 times of 70% ethanol to filter residue, and reflux for 1 hour in water bath. Filtered. The filtrate was combined twice, concentrated to obtain an extract, and dried under reduced pressure to give the extract powder of this example, 186 g.

Example 2: Preparation of composition B alcohol extract powder

Referring to the same method as in Example 1, except that 750 g of medicinal herbs, 75 g of fried berberine, 250 g of Codonopsis pilosula, 250 g of medlar, and 150 g of dried tangerine peel were weighed, and the extract powder of the present example was obtained, 154 g.

Example 3: Preparation of composition C alcohol extract powder

The same procedure as in the first embodiment was carried out except that 600 g of the medicinal flower head flower, 60 g of fried berberine, 200 g of ginseng, 200 g of medlar, and 200 g of schisandra were weighed, and the extract powder of the present example was obtained, 140 g.

Example 4: Preparation of a single flower alcohol extract extract powder

The same procedure as in Example 1 was carried out, except that 900 g of the medicinal material calyx was weighed and extracted, and 89 g of the extract powder of this example was obtained.

Example 5: Preparation of fried flavonol extract extract powder

The same procedure as in Example 1 was carried out, except that 660 g of the medicinal material of Rhizoma Coptidis was weighed, and 133 g of the extract powder of this example was obtained.

Example 6: Preparation of composition A decoction extract powder

Weigh 600g of head flower, 60g of fried berberine, 120g of raw licorice, wash, add 8 times water to decoct for 1.5 hours, filter; filter residue added to 6 times water for 15 hours, filter, and combine two filtrates. The filtrate was concentrated to an extract and dried under reduced pressure to give an extract powder of this example, 122 g.

Example 7: Preparation of Composition B Decoction Extract Powder

The method was the same as in the same manner as in Example 5 except that 300 g of medicinal materials, 30 g of fried berberine, 100 g of Codonopsis pilosula, 100 g of medlar, and 60 g of dried tangerine peel were weighed, and the extract powder of this example was obtained, 95 g.

Example 8: Preparation of composition C decoction extract powder

Referring to the same method as in Example 5, except that 300 g of the medicinal flower head flower, 30 g of fried berberine, 100 g of Codonopsis pilosula, 100 g of medlar, and 100 g of Schisandra were weighed, and the extract powder of this example was obtained, 102 g.

Example 9: Preparation of head flower 蓼 single decoction extract powder

The same procedure as in Example 5 was carried out, except that 1000 g of the medicinal material calyx was weighed and extracted, and the extract powder of this example was obtained, 109 g.

Example 10: Preparation of fried Huanglian decoction powder

The same procedure as in Example 5 was carried out except that 520 g of the Rhizoma Coptidis medicinal material was weighed, and the extract powder of this example was obtained, 95 g.

Example 11: Preparation of Composition A Water Extract Powder

Referring to the same method as in Example 1, the difference was that 80 kg of head flower buds, 8 kg of fried berberine, and 16 kg of raw licorice were weighed and extracted to obtain 8.1 kg of the extract powder of this example.

Example 12: Preparation of composition B water extract powder

Referring to the same method as in Example 1, the difference was that 54 kg of the flower head flower, 5.6 kg of fried berberine, 17.6 kg of Codonopsis pilosula, 17.6 kg of medlar, and 10.4 kg of dried tangerine peel were weighed, and the extract powder of this example was obtained, 17.0 kg.

Example 13: Preparation of composition C water extract powder

Referring to the same method as in Example 1, the difference was that 48 kg of the flower head flower, 4.8 kg of fried berberine, 16 kg of Codonopsis pilosula, 16 kg of medlar, and 16 kg of Schisandra were weighed, and the extract powder of this example was obtained, 20.0 kg.

Example 14: Preparation of fried yellow water extract extract powder

Referring to the same method as in Example 1, the difference was that 76 kg of the medicinal material was weighed and extracted, and the extract powder of this example was obtained, 3.1 kg.

Example 15: Preparation of Composition A Alcohol Extract Powder

The same procedure as in Example 1 was carried out except that 500 g of the head flower buds, 50 g of fried berberine, and 100 g of raw licorice were weighed and extracted to obtain the extract powder of the present example, 64.2 g.

Example 16: Preparation of Composition B Alcohol Extract Powder

The same procedure as in Example 1 was carried out except that 300 g of the medicinal material head flower, 30 g of fried berberine, 100 g of Codonopsis pilosula, 100 g of medlar, and 60 g of dried tangerine peel were weighed, and the extract powder of this example was obtained, 78 g.

Example 17: Preparation of composition C alcohol extract powder

The same procedure as in Example 1 was carried out, except that 300 g of the medicinal flower head flower, 30 g of fried berberine, 100 g of Codonopsis pilosula, 100 g of medlar, and 100 g of Schisandra were weighed, and the extract powder of this example was obtained, 85.4 g.

Example 18: Preparation of cedarol extract powder

The same procedure as in Example 1 was carried out, except that 600 g of the medicinal plant head flower was weighed and extracted, and the extract powder of this example was obtained, 50.2 g.

Example 19: Preparation of composition D alcohol extract powder

The same procedure as in Example 1 was carried out except that 300 g of the medicinal material head flower, 30 g of fried berberine, 100 g of Codonopsis pilosula, and 100 g of medlar were weighed, and the extract powder of this example was obtained, 78.8 g.

Example 20: Preparation of Composition D Decoction Extract Powder

The same procedure as in Example 5 was carried out except that 300 g of the medicinal material calyx, 30 g of fried berberine, 100 g of Codonopsis pilosula, and 100 g of medlar were weighed, and the extract powder of this example was obtained, 79 g.

Example 21: Preparation of composition E alcohol extract powder

The same procedure as in Example 1 was carried out except that 300 g of the medicinal material head flower, 30 g of fried berberine, 100 g of medlar, and 60 g of dried tangerine peel were weighed, and the extract powder of this example was obtained, 64 g.

Example 22: Preparation of composition E decoction extract powder

The same procedure as in Example 5 was carried out except that 300 g of the medicinal material head flower, 30 g of fried berberine, 100 g of medlar, and 60 g of dried tangerine peel were weighed, and the extract powder of this example was obtained, 66 g.

Example 23: Preparation of composition F alcohol extract powder

Referring to the same method as in Example 1, the difference was that 300 g of the medicinal material calyx, 30 g of fried berberine, 100 g of Codonopsis pilosula, and 100 g of Schisandra were weighed, and the extract powder of the present example was obtained, 80 g.

Example 24: Preparation of composition F decoction extract powder

Referring to the same method as in Example 5, the difference was that 300 g of the medicinal material head flower, 30 g of fried berberine, 100 g of Codonopsis pilosula, and 100 g of schisandra were weighed, and the extract powder of this example was obtained, 84 g.

Example 25: Preparation of composition G alcohol extract powder

The same procedure as in Example 1 was carried out except that 300 g of the medicinal material head flower, 30 g of fried berberine, 100 g of medlar, and 100 g of schisandra were weighed, and the extract powder of this example was obtained, 86 g.

Example 26: Preparation of composition G decoction extract powder

The same procedure as in Example 5 was carried out except that 300 g of the medicinal material head flower, 30 g of fried berberine, 100 g of medlar, and 100 g of schisandra were weighed, and the extract powder of this example was obtained, 88 g.

Pharmacological experiment

Test Example 1 : Composition (Example 1) Detection of antibacterial activity against H. pylori standard strains and clinical strains.

1) Experimental strain:

Clinical strain: The strain used was H. pylori ATCC700392 and the Helicobacter pylori SS1 international standard sequencing strain, which was purchased from ATCC (American Type Culture Collection).

Drug-resistant strains: collected in clinical digestive medicine, verified by drug sensitivity test. Three strains (named) and their characteristics were clinically isolated:

HP R-1 type: it is resistant to metronidazole,

HP R-2 type: it is resistant to amoxicillin,

HPR-3: It is resistant to clarithromycin.

2) The main reagent used in the test

Columbia blood agar powder, brain heart infusion agar dry powder purchased from the United Kingdom Oxoid company, vancomycin hydrochloride, amphotericin, polymyxin B, sulfonamide (TMP), amoxicillin, clarithromycin, metronidazole from Sigma, USA, the enzyme, oxidase and urease were purchased from BioMerieux, and the sterile defibrinated sheep blood was purchased from Nanjing Diagnostic Biotechnology Co., Ltd., and anhydrous ethanol (analytical grade) was purchased from Chongqing Chongqing Chuandong Chemical Co., Ltd. The company's chemical reagent factory, dimethyl sulfoxide (DMSO) analysis was purely purchased from Beijing Hao Laibao Technology Co., Ltd.

3) Test sample

The composition obtained in a part of the embodiment of the present invention; the single flower extract of the head flower obtained in Examples 4 and 9.

4) Preparation of main reagents and materials:

4.1) Preparation of drug-containing plates:

According to the requirements of in vitro susceptibility testing, two parallel experiments should be set for each drug concentration of each strain during the experiment, and the experiment should be repeated three times. Each time, 1.95 g of Columbia blood agar powder was weighed and dissolved in 39.5 mL of deionized water in an Erlenmeyer flask. After autoclaving, 5 mL of defibrated sterile sheep blood (10%) was added while the medium was cooled to 50-55 ° C. 0.5mL mixed antibiotics (1%), then add 5mL of the corresponding dilution of the drug solution, mix and pour into 2 sterile dishes (d = 90mm), and store at 4 °C after solidification. The dilution of the single flower and the composition solution of the head flower and the drug concentration of the corresponding plate are shown in Table 1.

4.2) Preparation of vehicle-containing blood plate (solvent control): The method is the same as the preparation of the blood plate containing the sample, that is, the corresponding concentration of dimethyl sulfoxide is added to replace the sample mother liquor, and the double distilled water is used as the solvent without preparation.

5) Experimental method

5.1) Resuscitation culture and identification of strains of Helicobacter pylori standard strains and clinical resistant strains

Helicobacter pylori ATCC700392 and Helicobacter pylori SS1 strains and clinical H.pylori-resistant amoxicillin, H.pylori-resistant clarithromycin, and H.pylori-resistant metronidazole were removed from the -80 °C refrigerator and placed at 37 °C. Dissolved in a water bath, uniformly coated on the Columbia blood plate containing the mixed antibiotics, and placed in a 37 ° C three-gas incubator (85% N ₂ , 10% CO ₂ , 5% O ₂ ). Cultivate for 48 hours. The culture characteristics, Gram stain, urease identification, catalase identification and oxidase identification of the two standard strains and three clinical strains were carried out.

5.2) Preparation of bacterial solution: scrape the colony or lawn on the blood plate to the pre-cooled tube containing 15mL brain heart infusion broth, centrifuge once and resuspend in 4 °C brain heart infusion broth, After the bacterial solution was diluted 10 times, 100 times and 1000 times, the OD600 value of the bacterial liquid was measured on an ultraviolet spectrophotometer. The result was that the OD value between 0.1 and 1.0 had a good linear relationship with the concentration of the bacterial liquid. The formula for calculating the content is as follows: the amount of bacteria/mL = 2.2 × 10 ⁸ × OD ₆₀₀ value × dilution factor, and the bacterial solution is diluted to obtain 10 ⁸ CFU/mL. The bacterial solution was prepared and inoculated within 15 minutes, and the bacterial solution was kept at 4 °C during the inoculation.

5.3) Clinical drug-resistant strain verification test: The clinical strain of Helicobacter pylori cultured for 72 hours was prepared with brain heart infusion broth, and the concentration was adjusted to 1～9×108 CFU/mL, respectively, and the bacteria were stained with sterile cotton swab. The suspension was uniformly applied to a drug culture dish and a blank culture dish at a concentration of 256 μg/mL of metronidazole, 256 μg/mL of clarithromycin and 256 μg/mL of amoxicillin, and two tablets were applied to each drug concentration, and placed in a microplate. Incubate at 37 ° C for 72 h in an aerobic environment. Under the condition that H.pylori grew well on a blank culture dish, the growth was observed, and Gram stain and biochemical identification tests were performed on the grown bacteria.

5.4) In vitro antibacterial activity test of the first flower bud composition

5.4.1) Bacterial solution coating: Draw a concentration of 108 CFU/mL bacterial solution with a disposable cotton swab and apply evenly on the surface of the agar. Two plates were coated for each concentration of each sample. At the same time, a negative control (ie no bacteria added), a growth control (ie no experimental sample), and a solvent control were provided for each two plates.

5.4.2) Culture: The results were observed after 48 hours of incubation in a three-gas incubator at 37 °C. The in vitro antibacterial activity test for each strain of each sample was repeated three times.

5.4.3) Completely sterile growth in the absence of growth in the negative control (ie no addition), growth control (ie no dosing), good growth, solvent control (ie, only solvent addition), no growth inhibition The highest dilution of the sample is the minimum inhibitory concentration (MIC) of the strain against the corresponding sample.

6) Experimental results:

6.1) Identification of Helicobacter pylori

Two strains of Helicobacter pylori ATCC700392 and SS1 and clinical isolates were placed on micro-aerobic strips on common Columbia blood plates. After 48 hours of culture, the colonies were needle-like, colorless and transparent, smooth and moist, with neat edges, raised, and small droplets. The lawn was grayish white and shiny.

Biochemical test: positive for urease test, positive for oxidase test, positive for catalase test; observed under microscope oil mirror, typical seagull-like, S-shaped, Gram-negative.

6.2) Verification of resistant strains

Three clinically resistant strains of H. pylori-resistant amoxicillin, H. pylori-resistant clarithromycin, and H. pylori-resistant metronidazole were collected and the drug resistance was verified. At the drug concentration of metronidazole 256μg / mL, clarithromycin 256μg / mL, amoxicillin 256μg / mL were good growth, no difference with the blank group.

6.3) The in vitro antibacterial test results of the head flower bud composition are shown in Table 2.

The MIC of the first flower bud composition to Hp ATCC700392 and SS1 was 0.5 mg/ml.

In the parallel test of this experiment, the sensitivity of amoxicillin, metronidazole and clarithromycin to the five species of H. pylori in the above table was also verified. The results showed that the three drugs were sensitive to ATCC700392 and SS1. HP R-1 is resistant to clarithromycin and sensitive to two other drugs; HP R-2 is resistant to amoxicillin and sensitive to two other drugs; HP R-3 is resistant to metronidazole, and the other two A drug is sensitive. The MIC of the head flower buds to Hp ATCC700392 and SS1 was 4 mg/ml, and the previous experimental results were verified.

Test Example 2 : Detection of antibacterial activity of the head bud composition against the Helicobacter pylori standard strain and the clinical isolate.

Basically referring to the method of Test Example 1, the first flower bud composition obtained in Examples 2-3, 5-8, and 9 was used as a reagent to test the resistance to ATCC700392, Helicobacter pylori SS1 international standard sequencing strain, and Helicobacter pylori. Antibacterial activity of metronidazole strain, Helicobacter pylori-resistant amoxicillin strain, and Helicobacter pylori-resistant clarithromycin strain. In the negative control (ie no addition) no growth, growth control (ie no drug) growth, solvent control (ie, only solvent) no growth inhibition, metronidazole, amoxicillin, clarithromycin control Inhibition of HP ATCC700392, the minimum inhibitory concentration (MIC) of HPATCC700392 was 4 mg/ml in the case of the control of the single flower preparation of the head flower, and the experiment was repeated three times. In this experiment, all the compositions were tested against five H. pylori The MIC value is between 0.5 and 64 mg/ml. The antibacterial effect of Coptidis Rhizoma is good, and its MIC value is between <0.0625-0.25mg/ml. The experimental results are shown in Table 2.

Table 1 Dilution concentration of experimental sample solution

Table 2 In vitro antibacterial results (MIC) of the composition of the examples of the present invention against Helicobacter pylori

Test Example 3: Experiment on the antibacterial activity of the composition against Gramella

1) Test strain

1.1) Test strain

Methicillin-resistant Staphylococcus aureus S. aureus (Methicl-resistant, MRSA) 6 strains, methicillin-sensitive Staphylococcus aureus S. aureus (Methicin-suseptable, MSSA) 6 strains, methicillin-resistant epidermal grape 5 strains of staphylococcus epidermidis (MRSE), 5 strains of methicillin-sensitive Staphylococcus epidermidis (MSSE), Escherichia coli (ESBLS), Eco ⁺ 6 strains, Escherichia coli (non-ESBLS) Escherichia Coli, Eco-6 strain, Klebsiella pneumoniae (ESBLs) K. penumonia, KPN ⁺ 6, strain Klebsiella (non-ESBLs) K. penumonia, KPN ^- 6 strain, Pseudomonas aeruginosa (PAE) 5 strains, 5 strains of Pseudomonas aeruginosa (PAE). The above strains were clinical isolates collected from June 2013 to October 2014 in Sichuan, Beijing, and Shanghai. The collection unit was identified by VITEK-60 automatic microbiological identification instrument.

1.2) Quality Control Strain

Staphylococcus aureus CMCC26003; Escherichia coli ATCC25922; Pseudomonas aeruginosa ATCC27853. Purchased from the Clinical Testing Center of the Ministry of Health of the People's Republic of China

2) Experimental reagents and materials

Cefepime (standard) is derived from the standard of China Food and Drug Control Institute; the head of the flower bed is supplied by Guiyang Medical College with the batch number of 14196 and the crude drug content of 10.35g/g.

3) Experimental method

The minimum inhibitory concentration of the in vitro antibacterial sample was determined by the agar double dilution method with the head flower unilateral, fried berberine unilateral and cefepime as the reference medicinal materials.

3.1) Cefepime reference substance

Weigh 9.5mg of the drug, add 4.1ml of normal saline, mix well, take 1ml each in two culture dishes, add 15ml of the medium to a final concentration of 145ug/ml, and then take 2ml in the vial. Then add 2ml of physiological saline to the vial, mix well, add 1ml each to add two plates, then add 15ml of the medium to a final concentration of 72.4ug/ml, and dilute according to this method to make the plate The final concentration of the drug contained therein was 128, 64, 32, 16, 8, 4, 2, 1, 0.5, 0.25, 0.125, 0.06, 0.03, 0.015, 0.008 ug/ml. After cooling, the bacteria were inoculated with a multi-point inoculation instrument (MIT-P, SUKUMA), the inoculum amount was about 104 CFU/ml, 27 strains of bacteria were inoculated per dish, 54 strains were inoculated in 2 dishes, and the lid was covered. The cells were cultured in a 35-37 ° C incubator for 18-20 hours, and the results were observed. The minimum concentration of the drug in which no bacterial growth was observed in the plate was judged as the minimum inhibitory concentration (MIC).

3.2) Head flower 蓼方, Huanglian extract and test sample preparation method

Take a sterilized beaker, add 7.68 g of the weighed Chinese medicine sample, and then add 60 ml of the melted MH agar medium at about 50 ° C, mix and mix 15 ml into two plates to make the concentration 128 mg / Ml, then add 30 ml of the medium in the remaining 30 ml of medium, mix well, and then draw 15 ml from each of the two culture dishes to a concentration of 64 mg / ml, according to this method, the ratio is diluted to make each dish The final concentrations of the drug-containing drugs were 128, 64, 32, 16, 8, 4, 2, 1, 0.5, 0.25, 0.125, 0.06, 0.03, 0.015, and 0.008 mg/ml, respectively. After cooling, the bacteria were inoculated with a multi-point inoculation instrument (MIT-P, SUKUMA), the inoculum volume was about 10 ⁴ CFU/ml, 27 strains of bacteria were inoculated per dish, 54 strains were inoculated in 2 dishes, and the lid was covered. The cells were cultured in a 35-37 ° C incubator for 18-20 hours, and the results were observed.

4) Experimental results

The experimental results show that the first flower bud composition has a good inhibitory effect on Gram-negative bacteria and Gram-positive bacteria. The experimental results are shown in Table 3.

Table 3 Table of bacteriostatic MIC results of Gramella in the examples of the present invention

Claims

A pharmaceutical composition characterized in that the composition comprises a head flower bud and a berberine.
A pharmaceutical composition comprising 20-60 parts by weight of a head flower and 2-6 parts by weight of a berberine.
The composition according to Claim 1 wherein said composition consists of the head bud, berberine, and a composition selected from any one or more of the following: (1) a heat-clearing drug; (2) a tonic drug (3) Lishui osmotic drug; (4) qi medicine; (5) phlegm; (6) blood circulation phlegm; (7) cooling blood hemostasis; (8) phlegm and blood stasis; (9) ) Wenyang cold medicine; (10) digestion medicine; (11) solution medicine.
A pharmaceutical composition according to claim 3, characterized in that

The heat-clearing medicine is selected from the group consisting of dandelion, andrographis paniculata, radix astragali, phellodendron, radix isatidis, barley, honeysuckle, phloem, nasturtium, houttuynia, purple diced, peony bark, eucalyptus honey, water flower, medlar, white flower snake Tongcao, Scutellaria barbatarum, Rehmannia glutinosa, Brucea javanica, Dalbergia; but does not include head flower buds, berberine;

The tonic drug is selected from the group consisting of licorice, Codonopsis, Atractylodes, Radix Paeoniae Alba, jujube, ginseng, tea, astragalus, and Huangjing;

The water-wetting agent is selected from the group consisting of cockroaches, knotweed, and earthworms;

The qi medicine is selected from the group consisting of dried tangerine peel, woody fragrant, citrus aurantium, fragrant sage, perilla stalk, August stalk, and earthworm mustard;

The collecting agent is selected from the group consisting of Schisandra, Chinese wolfberry, pomegranate peel, ebony, and jellyfish;

The blood stasis and expectorant is selected from the group consisting of Yanhusuo, Sanqi, Salvia, Shijiantong, Yujin, and Rhubarb;

The cooling blood hemostasis agent is selected from the group consisting of white and mantle;

The phlegm-relieving peony is selected from the group consisting of Pinellia ternata, Magnolia, Spirulina, and Ginkgo;

The Wenyang cold medicine is selected from the group consisting of Wujing, galangal, pepper, dried ginger, and wild worm;

The digestion agent is selected from the group consisting of garlic, hawthorn and betel nut;

The solution is selected from the group consisting of cassia twig, ginger, perilla leaf, and Bupleurum.
The composition according to Claim 3, characterized in that said composition consists of any of the following eleven classes of drugs: cephalosporin, berberine, and any of the following eleven classes of drugs: (1) heat-clearing drugs; (2) tonic drugs (3) Lishui osmotic drug; (4) qi medicine; (5) phlegm; (6) blood circulation phlegm; (7) cooling blood hemostasis; (8) phlegm and blood stasis; (9) ) Wenyang cold medicine; (10) digestion medicine; (11) solution medicine.
The composition according to claim 4, wherein said composition is selected from any one of the following groups:

The composition according to 1.1 includes a head flower bud, a berberine, and a heat-clearing drug;

The composition of 1.2 includes a head flower bud, a berberine, and a tonic drug;

The composition of 1.3 includes a head flower bud, a berberine, and a water-wetting agent;

The composition of 1.4 includes a head flower bud, a berberine, and a gas medicine;

The composition of 1.5 includes a flower bud, a berberine, and a sputum;

The composition described in 1.6 includes a head flower bud, a berberine, a blood stasis medicine;

The composition described in 1.7 includes a head flower bud, a berberine, and a blood-suppressing hemostatic agent;

The composition of 1.8 includes a head flower bud, a berberine, and a phlegm-relieving peony;

The composition described in 1.9 includes a flower bud, a berberine, and a warming and dispelling cold medicine;

The composition according to 1.10 includes a head flower bud, a berberine, and a digestion drug;

The composition according to 1.11 includes a head flower bud, a berberine, and a solution.
A pharmaceutical composition according to claim 6 wherein

The composition comprising the group of the head flower bud, the berberine, and the heat-clearing drug is selected from any one of the following groups:

(1) 20-60 parts by weight of the head flower, 2-6 parts by weight of the berberine, and 10-15 parts by weight of the dandelion;

(2) 20-60 parts by weight of the head flower, 2-6 parts by weight of the berberine, and 15-25 parts by weight of the houttuynia cordata;

(3) 20-60 parts by weight of the head flower, 2-6 parts by weight of berberine, 3-12 parts by weight of Phellodendron, 3-10 parts by weight of astragalus, 6-10 parts by weight of medlar;

The composition comprising the group of the head flower bud, the berberine, and the tonic drug is selected from any one of the following groups:

(1) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, and 9-15 parts by weight of huangjing;

(2) 10-90 parts by weight of the head flower, 1-10 parts by weight of berberine, and 2-20 parts by weight of licorice;

(3) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, and 9-18 parts by weight of Codonopsis pilosula;

(4) 20-60 parts by weight of the head flower, 2-6 parts by weight of berberine, 9-18 parts by weight of Codonopsis pilosula, 4-9 parts by weight of licorice;

The composition comprising the group of flower head, berberine, and water-wetting agent is selected from any one of the following groups:

(1) head flower 蓼 20-60, berberine 2-6 parts by weight, 茯苓 9-15 parts by weight;

The composition comprising the group of head flower buds, berberine, and qi medicine is selected from any one of the following groups:

(1) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, and 5-10 parts by weight of dried tangerine peel;

The composition comprising the group of flower head, berberine, and sputum is selected from any one of the following groups:

(1) 20-60 parts by weight of the head flower, 2-6 parts by weight of the berberine, and 8-12 parts by weight of the schisandra.
The composition according to claim 3, wherein said composition consists of any of the first two classes of drugs: cephalopod, berberine, and eleventh medicinal;

The composition described in 2.1 includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug;

The composition described in 2.2 includes a head flower bud, a berberine, a heat-clearing drug, and a water-wetting agent;

The composition described in 2.3 includes a head flower bud, a coptis, a heat-clearing drug, and a qi medicine;

The composition according to 2.4 includes a head flower bud, a berberine, a heat-clearing drug, and a sputum drug;

The composition of 2.5 includes a head flower bud, a berberine, a heat-clearing drug, a blood stasis drug;

The composition described in 2.6 includes a head flower bud, a berberine, a heat-clearing drug, a cooling blood hemostatic drug;

The composition described in 2.7 includes a flower bud, a coptis, a heat-clearing drug, and a phlegm-relieving peony;

The composition described in 2.8 includes a flower bud, a berberine, a heat-clearing drug, and a warming and dispelling cold medicine;

The composition described in 2.9 includes a head flower bud, a berberine, a heat-clearing drug, and a digestive drug;

The composition described in 2.10 includes a flower bud, a coptis, a heat-clearing drug, and a drug;

The composition according to 2.11 includes a head flower bud, a berberine, a tonic drug, and a water-wetting agent;

The composition according to 2.12 includes a head flower bud, a berberine, a tonic drug, and a qi medicine;

The composition according to 2.13 includes a head flower bud, a berberine, a tonic medicine, and a sputum medicine;

The composition according to 2.14 includes a head flower bud, a berberine, a tonic drug, a blood stasis drug;

The composition according to 2.15 includes a head flower bud, a berberine, a tonic medicine, a cooling blood hemostasis;

The composition according to 2.16 includes a head flower bud, a berberine, a tonic drug, and a phlegm and blood stasis drug;

The composition according to 2.17 includes a head flower bud, a berberine, a tonic drug, and a warming and dispelling cold medicine;

The composition according to 2.18 includes a head flower bud, a berberine, a tonic drug, and a digestive drug;

The composition according to 2.19 includes a head flower bud, a berberine, a tonic drug, and a solution;

The composition according to 2.20 includes a flower bud, a berberine, a leachate, and a qi;

The composition according to 2.21 includes a flower bud, a berberine, a leachate, and a sputum;

The composition according to 2.22 includes a flower bud, a berberine, a leachate, a blood stasis drug;

The composition according to 2.23 includes a head flower bud, a berberine, a leachhin, a cooling blood hemostatic drug;

The composition according to 2.24 includes a flower bud, a berberine, a leachate, and a phlegm;

The composition according to 2.25 includes a flower bud, a berberine, a leachate, and a warming and dispelling cold medicine;

The composition according to 2.26 includes a flower bud, a berberine, a leachate, and a digestive;

The composition according to 2.27 includes a head flower bud, a berberine, a leachate, and a solution;

The composition according to 2.28 includes a head flower bud, a berberine, a qi medicine, and a sputum medicine;

The composition according to 2.29 includes a head flower bud, a berberine, a qi medicine, a blood circulation phlegm;

The composition according to 2.30 includes a head flower bud, a berberine, a qi medicine, a cooling blood hemostasis;

The composition according to 2.31 includes a head flower bud, a berberine, a qi medicine, a phlegm and blood stasis medicine;

The composition according to 2.32 includes a head flower bud, a berberine, a qi medicine, a warming and dispelling cold medicine;

The composition according to 2.33 includes a head flower bud, a berberine, a qi medicine, and a digestive medicine;

The composition according to 2.34 includes a head flower bud, a berberine, a qi medicine, and a prescription drug;

The composition according to 2.35 includes a head flower bud, a berberine, a sputum medicine, a blood stasis medicine;

The composition according to 2.36 includes a flower bud, a berberine, a phlegm, and a blood-suppressing hemostatic agent;

The composition according to 2.37 includes a flower bud, a berberine, a phlegm, and a phlegm;

The composition according to 2.38 includes a head flower bud, a berberine, a sputum medicine, and a warming and dispelling cold medicine;

The composition according to 2.39 includes a flower bud, a berberine, a sputum, and a digestive;

The composition according to 2.40 includes a flower bud, a berberine, a sputum, and a remedy;

The composition according to 2.41 includes a head flower bud, a berberine, a blood circulation phlegm medicine, a cooling blood hemostatic drug;

The composition according to 2.42 includes a flower bud, a berberine, a blood stasis phlegm, and a phlegm phlegm;

The composition according to 2.43 includes a flower bud, a berberine, a blood stasis drug, and a warming and dispelling cold medicine;

The composition according to 2.44 includes a flower bud, a berberine, a blood stasis drug, and a digestive drug;

The composition according to 2.45 includes a flower bud, a berberine, a blood stasis drug, and a drug;

The composition according to 2.46 includes a head flower bud, a berberine, a cooling blood hemostasis, and a phlegm and blood stasis medicine;

The composition according to 2.47 includes a head flower bud, a berberine, a cooling blood hemostasis, and a warming and dispelling cold medicine;

The composition according to 2.48 includes a head flower bud, a berberine, a cooling blood hemostatic drug, and a digestive drug;

The composition according to 2.49 includes a head flower bud, a berberine, a cooling blood hemostasis, and a solution;

The composition according to 2.50 includes a flower bud, a berberine, a phlegm and blood stasis medicine, and a warming and dispelling cold medicine;

The composition according to 2.51 includes a flower bud, a berberine, a phlegm and blood stasis medicine, and a digestive medicine;

The composition according to 2.52 includes a head flower bud, a berberine, a phlegm-relieving peony, and a solution;

The composition described in 2.53 includes a head flower bud, a berberine, a warming and dispelling cold medicine, and a digestive medicine;

The composition described in 2.54 includes a head flower bud, a berberine, a warming and dispelling cold medicine, and a solution;

The composition of 2.55 includes a head flower bud, a coptis, an anti-drug, and a solution.
The composition according to claim 8 wherein

The composition comprising the group of flower head, berberine, tonic, and water-wetting agent is selected from any one of the following groups:

(1) 20-60 parts by weight of the head flower, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, 9-15 parts by weight of hydrazine;

(2) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, 9-18 parts by weight of Codonopsis pilosula, and 9-15 parts by weight of medlar;

(3) 20-60 parts by weight of the head flower, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, 9-18 parts by weight of Codonopsis pilosula, 9-15 parts by weight of 茯苓;

(4) 20-60 parts by weight of the head flower, 2-6 parts by weight of berberine, 3-9 parts by weight of ginseng, 6-12 parts by weight of Atractylodes, 2-6 parts by weight of licorice, 9-15 parts by weight of hydrazine;

The composition comprising the group of flower head, berberine, tonic, and medicine is selected from any one of the following groups:

(1) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, 9-18 parts by weight of Codonopsis pilosula, and 5-10 parts by weight of dried tangerine peel;

(2) 20-60 parts by weight of the head flower, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, 5-10 parts by weight of dried tangerine peel;

(3) 20-60 parts by weight of the head flower, 2-6 parts by weight of berberine, 9-18 parts by weight of Codonopsis pilosula, 4-9 parts by weight of licorice, 5-10 parts by weight of dried tangerine peel;

The composition comprising the group of flower head, berberine, tonic, and sputum is selected from any one of the following groups:

(1) 20-60 parts by weight of the head flower, 2-6 parts by weight of berberine, 9-18 parts by weight of Codonopsis pilosula, and 8-12 parts by weight of Schisandra;

(2) 20-60 parts by weight of the head flower, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, and 8-12 parts by weight of Schisandra;

(3) 20-60 parts by weight of the head flower, 2-6 parts by weight of berberine, 9-18 parts by weight of Codonopsis pilosula, 4-9 parts by weight of licorice, and 8-12 parts by weight of Schisandra;

The composition comprising the group of flower head, berberine, tonic, and warming cold medicine is selected from any one of the following groups:

(1) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, 6-15 parts by weight of white peony, and 2-5 parts by weight of sorghum;

The composition comprising the group of flower head, berberine, tonic, and drug solution is selected from any one of the following groups:

(1) 20-60 parts by weight of the head flower, 2-6 parts by weight of berberine, 2-6 parts by weight of licorice, 6-15 parts by weight of white peony, 6-15 parts by weight of jujube, 3-10 parts by weight of cassia twig, Ginger 3-10 parts by weight;

The composition comprising the head flower bud, the berberine, the water permeable medicine, and the qi medicine are selected from any one of the following groups:

(1) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, 9-15 parts by weight of medlar, and 5-10 parts by weight of dried tangerine peel;

The composition comprising the head flower bud, the berberine, the leachate, and the sputum medicinal agent is selected from any one of the following groups:

(1) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, 9-15 parts by weight of quinone, and 8-12 parts by weight of schisandra;

The composition comprising the head flower bud, the berberine, the qi medicine, and the remedy group is selected from any one of the following groups:

(1) 20-60 parts by weight of the head flower, 2-6 parts by weight of Rhizoma Coptidis, 5-10 parts by weight of dried tangerine peel, and 8-12 parts by weight of Schisandra.
The composition according to claim 3, wherein said composition consists of any of three types of drugs: cephalopod, berberine, and the above eleventh medicinal properties;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, and a water-wetting agent;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, and a gas-making drug;

The composition includes a flower bud, a coptis, a heat-clearing drug, a tonic drug, and a sputum-receiving agent;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a blood circulation medicine;

The composition includes a flower bud, a coptis, a heat-clearing drug, a tonic drug, and a blood-suppressing hemostatic agent;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, and a phlegm-dampening phlegm;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, and a warming and dispelling cold medicine;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, and a digestion drug;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, and a solution;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, and a gas-making drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, and a sputum-receiving agent;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting agent, a blood-activating and stasis-removing drug;

The composition includes a flower bud, a berberine, a heat-clearing drug, a water-wetting drug, and a blood-suppressing hemostatic agent;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting agent, and a phlegm-dampening phlegm;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting agent, and a warm-yang dispersing drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting agent, and a digestive drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting agent, and a solution;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a qi medicine, and a sputum medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a qi medicine, a blood circulation phlegm medicine;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a qi medicine, and a cooling blood hemostatic drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a qi medicine, and a phlegm-dampening phlegm;

The composition includes a flower bud, a berberine, a heat-clearing drug, a qi medicine, and a warming and dispelling cold medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a qi medicine, and a digestion medicine;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a qi medicine, and a solution medicine;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a phlegm-removing drug, a blood-activating phlegm;

The composition includes a flower bud, a berberine, a heat-clearing drug, a phlegm-receiving drug, and a cooling blood-stopping drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a phlegm-receiving drug, and a phlegm-dampening phlegm;

The composition includes a flower bud, a berberine, a heat-clearing drug, a sputum medicinal agent, and a warming and dispelling cold medicine;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a sputum medicinal drug, and a digestive medicinal drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a sputum drug, and a remedy drug;

The composition includes a flower bud, a berberine, a heat-clearing drug, a blood-activating phlegm, and a cooling blood-stopping agent;

The composition includes a flower bud, a berberine, a heat-clearing drug, a blood-activating phlegm drug, and a phlegm-dampening phlegm;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a blood-activating phlegm medicine, and a warm-yang dispersing medicine;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a blood-activating phlegm drug, and a digestion drug;

The composition includes a flower bud, a berberine, a heat-clearing drug, a blood stasis drug, and a drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a cooling blood hemostatic drug, and a phlegm-dampening phlegm;

The composition includes a flower bud, a berberine, a heat-clearing drug, a cooling blood-stopping drug, and a warm-yang dispersing drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a cooling blood hemostatic drug, and a digestion drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a cooling blood hemostatic drug, and a solution;

The composition includes a flower bud, a berberine, a heat-clearing drug, a phlegm-dampening phlegm, and a warming and dispelling cold medicine;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a phlegm-dampening phlegm, and a digestive medicinal;

The composition includes a flower bud, a berberine, a heat-clearing drug, a phlegm-dampening phlegm, and a remedy;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a warming and dispelling cold medicine, and a digestive medicine;

The composition includes a flower bud, a coptis, a heat-clearing drug, a warming and dispelling cold medicine, and a solution;

The composition includes a flower bud, a coptis, a heat-clearing drug, a digestion drug, and a drug;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, and a qi medicine;

The composition includes a head flower bud, a berberine, a tonic drug, a leachhin, and a sputum;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, a blood-activating and stasis-removing drug;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, and a blood-suppressing hemostatic agent;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, and a phlegm-dampening phlegm;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, and a warm-yang dispersing drug;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, and a digestive drug;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, and a solution;

The composition includes a head flower bud, a berberine, a tonic drug, a qi medicine, and a sputum medicine;

The composition includes a head flower bud, a berberine, a tonic drug, a qi medicine, a blood circulation phlegm;

The composition includes a head flower bud, a berberine, a tonic drug, a qi medicine, a cooling blood hemostasis;

The composition includes a head flower bud, a berberine, a tonic drug, a qi medicine, a phlegm and blood stasis medicine;

The composition includes a head flower bud, a berberine, a tonic drug, a qi medicine, a warming and dispelling cold medicine;

The composition includes a head flower bud, a berberine, a tonic drug, a qi medicine, a digestion drug;

The composition includes a head flower bud, a berberine, a tonic drug, a qi medicine, a solution medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a sputum medicine, a blood circulation phlegm medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a sputum medicine, a cooling blood hemostasis;

The composition includes a head flower bud, a berberine, a tonic medicine, a phlegm medicine, and a phlegm and blood stasis medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a sputum medicine, a warming and dispelling medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a sputum medicine, and a digestion medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a sputum medicine, and a remedy;

The composition includes a head flower bud, a berberine, a tonic medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a blood circulation phlegm medicine, a phlegm and blood stasis medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a blood circulation phlegm medicine, a warm and cold medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a blood circulation phlegm medicine, and a digestion medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a blood circulation phlegm medicine, and a solution medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a cooling blood hemostasis, a phlegm and blood stasis medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a cooling blood hemostasis, and a warming and dispelling cold medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a cooling blood hemostasis, and a digestive medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a cooling blood hemostasis, and a solution;

The composition includes a head flower bud, a berberine, a tonic drug, a phlegm-dampening phlegm, and a warming and dispelling cold medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a phlegm and blood stasis medicine, and a digestion medicine;

The composition includes a head flower bud, a berberine, a tonic drug, a phlegm-dampening phlegm, and a remedy;

The composition includes a head flower bud, a berberine, a tonic drug, a warming and dispelling cold medicine, and a digestion drug;

The composition includes a head flower bud, a berberine, a tonic drug, a warming and dispelling medicine, and a solution;

The composition includes a head flower bud, a berberine, a tonic drug, a digestive drug, and a solution;

The composition includes a head flower bud, a berberine, a leachate, a qi medicine, and a sputum medicine;

The composition includes a flower bud, a berberine, a leachate, a qi medicine, a blood stasis medicine;

The composition includes a head flower bud, a berberine, a water-wetting agent, a qi medicine, a cooling blood hemostasis;

The composition includes a head flower bud, a berberine, a water-wetting agent, a qi medicine, and a phlegm-dampening phlegm;

The composition includes a head flower bud, a berberine, a water-wetting agent, a qi medicine, and a warm-yang dispersing medicine;

The composition includes a head flower bud, a berberine, a leachate, a qi medicine, a digestion drug;

The composition includes a flower bud, a berberine, a leachate, a qi medicine, and a remedy;

The composition comprises a head flower bud, a berberine, a leachate, a phlegm, a blood stasis drug;

The composition includes a head flower bud, a berberine, a water-wetting agent, a sputum medicine, a cooling blood hemostatic agent;

The composition includes a flower bud, a berberine, a leachate, a phlegm, and a phlegm;

The composition includes a flower bud, a berberine, a leachate, a sputum, a stagnation drug, and a stagnation agent;

The composition includes a flower bud, a berberine, a leachate, a phlegm, and a digestive;

The composition includes a head flower bud, a berberine, a leachate, a phlegm, and a remedy;

The composition includes a head flower bud, a berberine, a water-wetting agent, a blood-activating phlegm, and a blood-suppressing hemostatic agent;

The composition includes a flower bud, a berberine, a leachhin, a blood stasis drug, a phlegm and blood stasis drug;

The composition includes a flower bud, a berberine, a water-wetting agent, a blood-activating phlegm, and a warm-yang dispersing drug;

The composition includes a flower bud, a berberine, a leachhin, a blood stasis drug, and a digestive drug;

The composition includes a flower bud, a berberine, a leachhin, a blood stasis drug, and a remedy;

The composition includes a flower bud, a berberine, a leachhin, a blood-suppressing hemostatic agent, and a phlegm-dampening phlegm;

The composition includes a head flower bud, a berberine, a water-wetting drug, a cooling blood-stopping drug, and a warm-yang dispersing drug;

The composition includes a head flower bud, a berberine, a water-wetting agent, a cooling blood hemostatic drug, and a digestion drug;

The composition includes a head flower bud, a berberine, a water-wetting agent, a cooling blood hemostatic drug, and a solution;

The composition includes a head flower bud, a berberine, a water-wetting agent, a phlegm-dampening phlegm, and a warm-yang chilling agent;

The composition includes a flower bud, a berberine, a leachhin, a phlegm, and a phlegm;

The composition includes a flower bud, a berberine, a leachhin, a phlegm, and a remedy;

The composition includes a head flower bud, a berberine, a leachhin, a warming and dispelling medicine, and a digestive medicine;

The composition includes a head flower bud, a berberine, a water-wetting agent, a warm-yang dispersing medicine, and a solution;

The composition includes a head flower bud, a berberine, a leachhin, a digestive, a drug;

The composition includes a head flower bud, a berberine, a qi medicine, a sputum medicine, a blood circulation phlegm medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a sputum medicine, a cooling blood hemostasis;

The composition includes a head flower bud, a berberine, a qi medicine, a phlegm medicine, a phlegm and blood stasis medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a sputum medicine, a warm and cold medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a sputum medicine, and a digestion medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a sputum medicine, and a remedy;

The composition includes a head flower bud, a berberine, a qi medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a blood circulation phlegm medicine, a phlegm and blood stasis medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a blood circulation phlegm medicine, a Wenyang cold medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a blood circulation phlegm medicine, and a digestion medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a blood circulation phlegm medicine, a solution medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a cooling blood hemostasis, a phlegm and blood stasis medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a cooling blood hemostasis, a warming and dispelling cold medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a cooling blood hemostasis drug, and a digestion drug;

The composition includes a head flower bud, a berberine, a qi medicine, a cooling blood hemostasis, and a solution;

The composition includes a head flower bud, a berberine, a qi medicine, a phlegm and blood stasis medicine, and a warming and dispelling medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a phlegm-dampening phlegm medicine, and a digestive medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a phlegm phlegm, and a remedy;

The composition includes a flower bud, a berberine, a qi medicine, a yangyang cold medicine, and a digestion medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a Wenyang cold medicine, and a solution medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a digestion medicine, a solution medicine;

The composition includes a head flower bud, a berberine, a sputum medicinal herb, a blood circulation phlegm medicine, and a cooling blood hemostatic drug;

The composition includes a flower bud, a peony root, a sputum medicinal herb, a blood stasis phlegm, and a phlegm phlegm;

The composition includes a head flower bud, a berberine, a sputum medicinal herb, a blood circulation phlegm medicine, and a yangyang cold medicine;

The composition includes a head flower bud, a berberine, a sputum medicinal, a blood stasis phlegm, and a digestive medicinal;

The composition includes a head flower bud, a berberine, a phlegm, a blood stasis drug, and a remedy;

The composition includes a head flower bud, a berberine, a phlegm, a blood-suppressing hemostatic agent, and a phlegm-dampening phlegm;

The composition includes a head flower bud, a berberine, a sputum medicinal medicine, a cooling blood hemostasis, and a warming and dispelling cold medicine;

The composition includes a flower bud, a berberine, a phlegm, a blood-suppressing hemostatic agent, and a digestive medicinal agent;

The composition includes a head flower bud, a berberine, a phlegm, a blood-suppressing hemostatic agent, and a remedy;

The composition includes a head flower bud, a berberine, a sputum medicinal herb, a phlegm-dampening phlegm, and a warming and dispelling cold medicine;

The composition includes a flower bud, a peony root, a phlegm, a phlegm, and a phlegm;

The composition includes a flower bud, a peony root, a phlegm, a phlegm, and a remedy;

The composition includes a head flower bud, a berberine, a sputum medicinal medicine, a warming and dispelling cold medicine, and a digestive medicine;

The composition includes a head flower bud, a berberine, a sputum medicinal medicine, a warming and dispelling cold medicine, and a remedy;

The composition includes a flower bud, a berberine, a sputum, a digestive, and a remedy;

The composition includes a head flower bud, a berberine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a phlegm and blood stasis medicine;

The composition includes a head flower bud, a berberine, a blood circulation phlegm medicine, a cooling blood hemostasis drug, a warm and cold powder medicine;

The composition includes a head flower bud, a berberine, a blood circulation phlegm medicine, a cooling blood hemostasis drug, and a digestion drug;

The composition includes a head flower bud, a berberine, a blood circulation phlegm, a cooling blood hemostasis, and a solution;

The composition includes a flower bud, a berberine, a blood stasis drug, a phlegm and blood stasis drug, and a warming and dispelling cold medicine;

The composition includes a flower bud, a berberine, a blood stasis, a phlegm and blood stasis drug, and a digestive drug;

The composition includes a flower bud, a berberine, a blood stasis, a phlegm, and a remedy;

The composition includes a flower bud, a berberine, a blood stasis drug, a warming and dispelling cold medicine, and a digestion drug;

The composition includes a flower bud, a berberine, a blood stasis drug, a warming and dispelling cold medicine, and a solution;

The composition includes a flower bud, a berberine, a blood stasis, a digestive, and a remedy;

The composition includes a head flower bud, a berberine, a blood-suppressing hemostatic agent, a phlegm-dampening phlegm medicine, and a warm-yang dispersing medicine;

The composition includes a head flower bud, a berberine, a cooling blood hemostasis, a phlegm and blood stasis medicine, and a digestion medicine;

The composition includes a flower bud, a berberine, a blood-suppressing hemostatic agent, a phlegm-dampening phlegm, and a remedy;

The composition includes a head flower bud, a berberine, a cooling blood hemostasis, a warming and dispelling cold medicine, and a digestive medicine;

The composition includes a head flower bud, a berberine, a cooling blood hemostasis, a warming and dispelling cold medicine, and a solution;

The composition includes a head flower bud, a berberine, a cooling blood hemostasis, a digestive medicine, and a solution;

The composition includes a flower bud, a berberine, a phlegm and blood stasis medicine, a warming and dispelling cold medicine, and a digestion medicine;

The composition includes a flower bud, a berberine, a phlegm-dampening phlegm, a warming and dispelling cold medicine, and a remedy;

The composition includes a flower bud, a berberine, a phlegm-dampening phlegm, an anti-drug, and a remedy;

The composition includes a flower bud, a berberine, a yangyang cold medicine, a digestive medicine, and a remedy.
The composition according to claim 10, characterized in that

The composition comprising the head flower bud, the berberine, the tonic medicine, the water-wetting agent, and the qi medicine are selected from any one of the following groups:

(1) 10-90 parts by weight of the head flower, 1-10 parts by weight of Rhizoma Coptidis, 3-50 parts by weight of Codonopsis pilosula, 3-30 parts by weight of medlar, 2-20 parts by weight of dried tangerine peel;

(2) 20-60 parts by weight of the head flower, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel;

(3) 20-60 parts by weight of the head flower, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, 9-18 parts by weight of Codonopsis pilosula, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel;

The composition comprising the head flower bud, the berberine, the tonic drug, the lyophilized drug, and the sputum medicinal agent are selected from any one of the following groups:

(1) 10-90 parts by weight of the head flower, 1-10 parts by weight of Rhizoma Coptidis, 3-50 parts by weight of Codonopsis pilosula, 3-30 parts by weight of medlar, and 2-20 parts by weight of Schisandra;

(2) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, 9-15 parts by weight of medlar, and 8-12 parts by weight of schisandra;

(3) 20-60 parts by weight of the head flower, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, 9-18 parts by weight of Codonopsis pilosula, 9-15 parts by weight of medlar, and 8-12 parts by weight of Schisandra;

The composition comprising the head flower bud, the berberine, the tonic medicine, the qi medicine, and the sputum medicine is selected from any one of the following groups:

(1) 20-60 parts by weight of the head flower, 2-6 parts by weight of Rhizoma Coptidis, 9-18 parts by weight of Codonopsis pilosula, 5-10 parts by weight of dried tangerine peel, and 8-12 parts by weight of Schisandra;

(2) 20-60 parts by weight of the head flower, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, 5-10 parts by weight of dried tangerine peel, and 8-12 parts by weight of Schisandra;

(3) 20-60 parts by weight of the head flower, 2-6 parts by weight of Rhizoma Coptidis, 9-18 parts by weight of Codonopsis pilosula, 4-9 parts by weight of licorice, 5-10 parts by weight of dried tangerine peel, 8-12 parts by weight of Schisandra;

The composition comprising the group consisting of the head flower bud, the berberine, the tonic medicine, the yangyang cold medicine, and the solution medicine is selected from the group consisting of:

(1) 20-60 parts by weight of head flower, 2-6 parts by weight of berberine, 2-6 parts by weight of licorice, 9-30 parts by weight of astragalus, 9-18 parts by weight of Codonopsis pilosula, 6-15 parts by weight of white peony, jujube 6-15 parts by weight, galangal 3-6 parts by weight, dried ginger 3-10 parts by weight, cassia twig 3-10 parts by weight;

The composition comprises a head flower bud, a berberine, a water permeable medicine, a qi medicine, and a sputum medicine selected from the group consisting of:

(1) 20-60 parts by weight of the head flower, 2-6 parts by weight of berberine, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, and 8-12 parts by weight of schisandra.
The composition according to claim 3, wherein said composition consists of any of four types of drugs: cephalopod, berberine, and any of the eleventh classes of medicinal properties;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, and a gas-making drug;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, and a sputum-receiving drug;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting agent, a blood-activating and stasis-removing drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, and a cooling blood-stopping agent;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, and a phlegm-dampening phlegm;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, and a warm-yang dispersing drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, and a digestive drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, and a solution;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a qi medicine, and a sputum medicine;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a qi medicine, a blood circulation phlegm medicine;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a qi medicine, and a cooling blood hemostatic drug;

The composition includes a flower bud, a coptis, a heat-clearing drug, a tonic drug, a qi medicine, and a phlegm-dampening phlegm;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a qi medicine, and a warming and dispelling cold medicine;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a qi medicine, and a digestion drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a qi medicine, and a solution medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a sputum medicine, a blood circulation phlegm medicine;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a phlegm-receiving drug, and a cooling blood-stopping drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a phlegm-receiving drug, and a phlegm-dampening phlegm;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a sputum medicinal agent, and a warming and dispelling cold medicine;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a sputum drug, and a digestion drug;

The composition includes a flower bud, a coptis, a heat-clearing drug, a tonic drug, a sputum drug, and a remedy drug;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a blood-activating phlegm drug, and a phlegm-dampening phlegm;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a blood-activating phlegm drug, and a warm-yang dispersing drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a blood-activating phlegm drug, and a digestion-eliminating drug;

The composition includes a flower bud, a coptis, a heat-clearing drug, a tonic drug, a blood-activating phlegm, and a remedy;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a cooling blood hemostasis, and a phlegm-dampening phlegm;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a cooling blood hemostasis, and a warming and dispelling cold medicine;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a cooling blood hemostasis drug, and a digestion drug;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a cooling blood hemostatic medicine, and a solution medicine;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a phlegm-dampening phlegm, and a warming and dispelling cold medicine;

The composition includes a flower bud, a coptis, a heat-clearing drug, a tonic drug, a phlegm-dampening phlegm, and a digestive medicinal agent;

The composition includes a flower bud, a coptis, a heat-clearing drug, a tonic drug, a phlegm-dampening phlegm, and a remedy;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a warming and dispelling cold medicine, and a digestion drug;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a warming and dispelling cold medicine, and a solution;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a digestion drug, and a solution;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a qi medicine, and a sputum medicine;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a qi medicine, a blood-activating phlegm;

The composition includes a flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a qi medicine, and a cooling blood-stopping agent;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a qi medicine, and a phlegm-dampening phlegm;

The composition includes a flower bud, a berberine, a heat-clearing drug, a water-wetting agent, a qi medicine, and a warm-yang dispersing medicine;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a gas-making drug, and a digestion drug;

The composition includes a flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a qi medicine, and a remedy;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a phlegm-receiving drug, a blood-activating phlegm drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a phlegm-receiving drug, and a cooling blood-stopping drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting agent, a phlegm-receiving agent, and a phlegm-dampening phlegm;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a phlegm-receiving drug, and a warm-yang dispersing drug;

The composition includes a flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a phlegm-receiving drug, and a digestion-reducing drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a phlegm-receiving drug, and a remedy drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a blood-activating phlegm drug, and a cooling blood-stopping drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a blood-activating phlegm drug, and a phlegm-dampening phlegm;

The composition includes a flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a blood-activating phlegm, and a warm-yang dispersing drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting agent, a blood-activating phlegm drug, and a digestion-eliminating drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting agent, a blood-activating phlegm, and a remedy;

The composition includes a flower bud, a coptis, a heat-clearing drug, a water-wetting drug, a cooling blood-stopping drug, and a phlegm-dampening phlegm;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a cooling blood-stopping drug, and a warm-yang dispersing drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a cooling blood-stopping drug, and a digestion-eliminating drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a cooling blood-stopping drug, and a solution-solving drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting agent, a phlegm-dampening phlegm, and a warm-yang dispersing drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting agent, a phlegm-dampening phlegm, and a digestion-eliminating drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting agent, a phlegm-dampening phlegm, and a remedy;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting agent, a warm-yang dispersing drug, and a digestive drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting agent, a warm-yang dispersing drug, and a solution;

The composition includes a flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a digestion drug, and a solution;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a qi medicine, a sputum medicine, a blood circulation phlegm medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a qi medicine, a sputum medicine, a cooling blood hemostatic medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a qi medicine, a phlegm medicine, and a phlegm-dampening phlegm;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a qi medicine, a sputum medicine, and a warm-yang dispersing medicine;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a qi medicine, a sputum medicine, and a digestion medicine;

The composition includes a flower bud, a coptis, a heat-clearing drug, a qi medicine, a sputum medicine, and a remedy;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a qi medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a qi medicine, a blood circulation phlegm medicine, a phlegm and blood stasis medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a qi medicine, a blood circulation phlegm medicine, and a Wenyang cold medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a qi medicine, a blood circulation phlegm medicine, and a digestion medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a qi medicine, a blood circulation phlegm medicine, and a remedy medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a qi medicine, a cooling blood hemostatic medicine, a phlegm and blood stasis medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a qi medicine, a cooling blood hemostasis, and a warm-yang dispersing medicine;

The composition includes a flower bud, a berberine, a heat-clearing drug, a qi medicine, a cooling blood hemostasis drug, and a digestion drug;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a qi medicine, a cooling blood hemostatic medicine, and a solution medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a qi medicine, a phlegm-dampening phlegm medicine, and a warm-yang dispersing medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a qi medicine, a phlegm-dampening phlegm medicine, and a digestion-reducing medicine;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a qi medicine, a phlegm-dampening phlegm, and a remedy;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a qi medicine, a warm-yang dispersing medicine, and a digestive medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a qi medicine, a Wenyang cold medicine, and a solution medicine;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a qi medicine, a digestion medicine, and a solution medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a sputum medicinal medicine, a blood circulation phlegm medicine, and a cooling blood hemostatic medicine;

The composition includes a flower bud, a berberine, a heat-clearing drug, a sputum medicinal herb, a blood-activating phlegm drug, and a phlegm-dampening phlegm;

The composition includes a flower bud, a coptis, a heat-clearing drug, a sputum medicinal herb, a blood-activating phlegm drug, and a warm-yang dispersing drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a sputum medicinal drug, a blood-activating phlegm drug, and a digestion-eliminating drug;

The composition includes a flower bud, a coptis, a heat-clearing drug, a sputum medicinal agent, a blood-activating phlegm drug, and a remedy drug;

The composition includes a flower bud, a berberine, a heat-clearing drug, a phlegm-receiving drug, a cooling blood-stopping drug, and a phlegm-dampening phlegm;

The composition includes a flower bud, a berberine, a heat-clearing drug, a phlegm-receiving drug, a cooling blood-stopping drug, and a warm-yang dispersing drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a phlegm-receiving drug, a cooling blood-stopping drug, and a digestive drug;

The composition includes a flower bud, a berberine, a heat-clearing drug, a sputum medicinal drug, a cooling blood hemostatic drug, and a remedy drug;

The composition includes a flower bud, a berberine, a heat-clearing drug, a phlegm-receiving medicinal herb, a phlegm-dampening phlegm drug, and a warm-yang dispersing drug;

The composition includes a flower bud, a berberine, a heat-clearing drug, a sputum medicinal herb, a phlegm-dampening phlegm drug, and a digestive medicinal drug;

The composition includes a flower bud, a coptis, a heat-clearing drug, a sputum medicinal herb, a phlegm-dampening phlegm drug, and a remedy drug;

The composition includes a flower bud, a berberine, a heat-clearing drug, a sputum medicinal agent, a warming and dispelling cold medicine, and a digestive medicinal agent;

The composition includes a flower bud, a berberine, a heat-clearing drug, a sputum medicinal agent, a warming and dispelling cold medicine, and a remedy;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a sputum medicinal drug, a digestive medicinal drug, and a remedy drug;

The composition includes a flower bud, a berberine, a heat-clearing drug, a blood-activating phlegm, a blood-suppressing hemostatic agent, and a phlegm-dampening phlegm;

The composition includes a flower bud, a berberine, a heat-clearing drug, a blood-activating phlegm, a cooling blood-stopping drug, and a warm-yang dispersing drug;

The composition includes a flower bud, a berberine, a heat-clearing drug, a blood-activating phlegm, a cooling blood-stopping drug, and a digestive drug;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, and a solution medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a blood-activating phlegm medicine, a phlegm-dampening phlegm medicine, and a warm-yang dispersing medicine;

The composition includes a flower bud, a berberine, a heat-clearing drug, a blood-activating phlegm, a phlegm-dampening phlegm, and a digestive;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a blood-activating phlegm, a phlegm-dampening phlegm, and a remedy;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a blood-activating phlegm medicine, a warm-yang dispersing medicine, and a digestive medicine;

The composition includes a flower bud, a berberine, a heat-clearing drug, a blood-activating phlegm, a warming and dispelling cold medicine, and a remedy;

The composition includes a flower bud, a berberine, a heat-clearing drug, a blood-activating phlegm, a digestion-eliminating drug, and a remedy;

The composition includes a flower bud, a berberine, a heat-clearing drug, a cooling blood-stopping drug, a phlegm-dampening phlegm, and a warming and dispelling cold medicine;

The composition includes a flower bud, a berberine, a heat-clearing drug, a cooling blood-stopping drug, a phlegm-dampening phlegm drug, and a digestive drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a cooling blood hemostasis, a phlegm-dampening phlegm, and a remedy;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a cooling blood hemostasis, a warming and dispelling cold medicine, and a digestive medicine;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a cooling blood hemostasis, a warming and dispelling cold medicine, and a solution medicine;

The composition includes a flower bud, a berberine, a heat-clearing drug, a cooling blood hemostatic drug, a digestive drug, and a solution;

The composition includes a flower bud, a berberine, a heat-clearing drug, a phlegm-dampening phlegm, a warming and dispelling cold medicine, and a digestive medicinal agent;

The composition includes a flower bud, a berberine, a heat-clearing drug, a phlegm-dampening phlegm, a warming and dispelling cold medicine, and a remedy;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a phlegm-dampening phlegm, an anti-drug, and a remedy;

The composition includes a flower bud, a berberine, a heat-clearing drug, a warming and dispelling cold medicine, a digestive medicine, and a solution medicine;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a qi medicine, and a sputum medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting agent, a qi medicine, a blood circulation medicine;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, a qi medicine, a cooling blood hemostatic agent;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, a qi medicine, and a phlegm-dampening phlegm;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, a qi medicine, and a warm-yang dispersing medicine;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a qi medicine, and a digestion drug;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a qi medicine, a solution medicine;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, a phlegm-receiving agent, a blood-activating phlegm;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, a phlegm-receiving drug, and a cooling blood-stopping agent;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, a phlegm-receiving agent, and a phlegm-dampening phlegm;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, a phlegm-receiving drug, and a warm-yang dispersing drug;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, a phlegm-receiving drug, and a digestive drug;

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting agent, a sputum medicine, and a remedy;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a blood-activating phlegm medicine, a cooling blood-stopping drug;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a blood-activating phlegm drug, and a phlegm-dampening phlegm;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, a blood-activating phlegm, and a warm-yang dispersing drug;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, a blood-activating phlegm drug, and a digestion-eliminating drug;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, a blood-activating phlegm, and a solution;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a cooling blood-stopping drug, and a phlegm-dampening phlegm;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a cooling blood-stopping drug, a warm-yang dispersing drug;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a cooling blood-stopping drug, and a digestion-eliminating drug;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a cooling blood hemostatic drug, and a solution;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a phlegm-dampening phlegm, and a warm-yang dispersing drug;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, a phlegm-dampening phlegm, and a digestive medicinal agent;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, a phlegm-dampening phlegm, and a remedy;

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting agent, a warm-yang dispersing medicine, and a digestive medicine;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, a warm-yang dispersing drug, and a solution;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, a digestive drug, and a solution;

The composition includes a head flower bud, a berberine, a tonic medicine, a qi medicine, a sputum medicine, a blood circulation phlegm medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a qi medicine, a sputum medicine, a cooling blood hemostasis;

The composition includes a head flower bud, a berberine, a tonic medicine, a qi medicine, a phlegm medicine, a phlegm and blood stasis medicine;

The composition includes a head flower bud, a berberine, a tonic drug, a qi medicine, a sputum medicine, a warming and dispelling medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a qi medicine, a sputum medicine, and a digestion medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a qi medicine, a sputum medicine, and a solution medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a qi medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a qi medicine, a blood circulation phlegm medicine, a phlegm and blood stasis medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a qi medicine, a blood circulation phlegm medicine, a warm and cold medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a qi medicine, a blood circulation phlegm medicine, and a digestion medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a qi medicine, a blood circulation phlegm medicine, and a remedy medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a qi medicine, a cooling blood hemostasis, a phlegm and blood stasis medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a qi medicine, a cooling blood hemostasis, a warm and cold medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a qi medicine, a cooling blood hemostasis, and a digestion medicine;

The composition includes a head flower bud, a berberine, a tonic drug, a qi medicine, a cooling blood hemostasis, and a solution;

The composition includes a head flower bud, a berberine, a tonic medicine, a qi medicine, a phlegm and blood stasis medicine, and a warming and dispelling medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a qi medicine, a phlegm-dampening phlegm medicine, and a digestion medicine;

The composition includes a head flower bud, a berberine, a tonic drug, a qi medicine, a phlegm phlegm, and a remedy;

The composition includes a head flower bud, a berberine, a tonic medicine, a qi medicine, a Wenyang cold medicine, and a digestion medicine;

The composition includes a head flower bud, a berberine, a tonic drug, a qi medicine, a warming and dispelling medicine, and a remedy;

The composition includes a head flower bud, a berberine, a tonic medicine, a qi medicine, a digestion medicine, a solution medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a phlegm medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a sputum medicine, a blood circulation phlegm medicine, a phlegm and blood stasis medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a sputum medicinal medicine, a blood circulation phlegm medicine, and a warm yang medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a sputum medicine, a blood circulation phlegm medicine, and a digestion medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a sputum medicine, a blood circulation phlegm medicine, and a remedy medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a sputum medicinal medicine, a cooling blood hemostasis, a phlegm and blood stasis medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a sputum medicinal medicine, a cooling blood stopping medicine, and a warming and dissipating cold medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a sputum medicine, a cooling blood hemostatic medicine, a digestion medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a sputum medicine, a cooling blood hemostatic medicine, and a remedy;

The composition includes a head flower bud, a berberine, a tonic drug, a sputum medicinal herb, a phlegm-dampening phlegm drug, and a warming and dispelling medicinal agent;

The composition includes a head flower bud, a berberine, a tonic medicine, a phlegm, a phlegm, and a phlegm;

The composition includes a head flower bud, a berberine, a tonic drug, a phlegm, a phlegm, and a remedy;

The composition includes a head flower bud, a berberine, a tonic medicine, a sputum medicinal medicine, a warming and dispelling cold medicine, and a digestive medicine;

The composition includes a head flower bud, a berberine, a tonic drug, a sputum medicinal agent, a warming and dispelling cold medicine, and a solution;

The composition includes a head flower bud, a berberine, a tonic drug, a sputum medicinal drug, a digestive medicinal drug, and a remedy drug;

The composition includes a head flower bud, a berberine, a tonic medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a phlegm and blood stasis medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a blood circulation phlegm medicine, a cooling blood hemostasis medicine, a warm and cold medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a digestion medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a solution medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a blood circulation phlegm medicine, a phlegm-dampening phlegm medicine, and a warm-yang dispersing medicine;

The composition includes a flower bud, a berberine, a tonic medicine, a blood stasis medicine, a phlegm and blood stasis medicine, and a digestion medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a blood stasis medicine, a phlegm and blood stasis medicine, and a solution medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a blood circulation phlegm medicine, a warm and cold medicine, and a digestion medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a blood circulation phlegm medicine, a yangyang cold medicine, a solution medicine;

The composition includes a head flower bud, a berberine, a tonic drug, a blood stasis drug, a digestion drug, a solution drug;

The composition includes a head flower bud, a berberine, a tonic medicine, a cooling blood to stop bleeding medicine, a phlegm and blood stasis medicine, and a warming and dispelling cold medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a cooling blood hemostasis, a phlegm and blood stasis medicine, and a digestive medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a cooling blood hemostasis, a phlegm and blood stasis medicine, and a solution medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a cooling blood hemostasis, a warming and dispelling cold medicine, and a digestive medicine;

The composition includes a head flower bud, a berberine, a tonic drug, a cooling blood hemostasis, a warming and dispelling cold medicine, and a solution;

The composition includes a head flower bud, a berberine, a tonic drug, a cooling blood hemostasis, a digestion drug, and a solution;

The composition includes a head flower bud, a berberine, a tonic medicine, a phlegm-dampening phlegm, a warming and dispelling medicine, and a digestive medicine;

The composition includes a head flower bud, a berberine, a tonic drug, a phlegm-dampening phlegm, a warming and dispelling cold medicine, and a solution;

The composition includes a head flower bud, a berberine, a tonic drug, a phlegm-dampening phlegm, an anti-drug, and a solution;

The composition includes a flower bud, a berberine, a tonic drug, a warming and dispelling medicine, a digestion drug, and a solution;

The composition includes a head flower bud, a berberine, a leachhin, a qi medicine, a sputum medicine, a blood stasis medicine;

The composition includes a head flower bud, a berberine, a water-wetting drug, a qi medicine, a sputum medicine, a cooling blood hemostasis;

The composition includes a head flower bud, a berberine, a leachhin, a qi medicine, a phlegm medicine, a phlegm and blood stasis medicine;

The composition includes a head flower bud, a berberine, a water-wetting agent, a qi medicine, a sputum medicine, and a warm-yang medicine;

The composition includes a head flower bud, a berberine, a leachhin, a qi medicine, a sputum medicine, and a digestion medicine;

The composition includes a head flower bud, a berberine, a water permeable medicine, a qi medicine, a sputum medicine, and a remedy medicine;

The composition includes a head flower bud, a berberine, a leachhin, a qi medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine;

The composition includes a head flower bud, a berberine, a leachate, a qi medicine, a blood circulation phlegm medicine, a phlegm and blood stasis medicine;

The composition includes a flower bud, a berberine, a water-wetting drug, a qi medicine, a blood-activating phlegm medicine, and a warm-yang dispersing medicine;

The composition includes a head flower bud, a berberine, a leachate, a qi medicine, a blood circulation phlegm medicine, and a digestion medicine;

The composition includes a flower bud, a berberine, a leachate, a qi medicine, a blood stasis medicine, and a remedy;

The composition includes a head flower bud, a berberine, a leachhin, a qi medicine, a cooling blood hemostasis, a phlegm and blood stasis medicine;

The composition includes a head flower bud, a berberine, a water-wetting drug, a qi medicine, a cooling blood hemostasis, and a warm-yang dispersing medicine;

The composition includes a flower bud, a berberine, a leachate, a qi medicine, a cooling blood hemostasis, and a digestive medicine;

The composition includes a head flower bud, a berberine, a leachhin, a qi medicine, a cooling blood hemostasis, and a solution;

The composition includes a head flower bud, a berberine, a water-wetting agent, a qi medicine, a phlegm-dampening phlegm medicine, and a warm-yang dispersing medicine;

The composition includes a head flower bud, a berberine, a leachhin, a qi medicine, a phlegm phlegm, and a digestive;

The composition includes a head flower bud, a berberine, a leachhin, a qi medicine, a phlegm phlegm, and a remedy;

The composition includes a flower bud, a berberine, a leachate, a qi medicine, a yangyang cold medicine, and a digestion medicine;

The composition includes a head flower bud, a berberine, a leachhin, a qi medicine, a yangyang cold medicine, and a remedy;

The composition includes a head flower bud, a berberine, a water permeable medicine, a qi medicine, a digestion medicine, a solution medicine;

The composition includes a head flower bud, a berberine, a leachhin, a phlegm, a blood stasis, a blood stasis and a hemostatic;

The composition includes a flower bud, a berberine, a leachhin, a phlegm, a blood stasis, a phlegm and blood stasis;

The composition includes a flower bud, a berberine, a leachate, a phlegm, a blood stasis, a warming and dispelling cold medicine;

The composition includes a head flower bud, a berberine, a leachate, a phlegm, a blood stasis, and a digestive;

The composition includes a head flower bud, a berberine, a leachhin, a phlegm, a blood stasis, and a remedy;

The composition includes a head flower bud, a berberine, a leachhin, a phlegm, a blood stasis, a phlegm and blood stasis;

The composition includes a head flower bud, a berberine, a leachate, a phlegm, a blood-suppressing medicine, a warm-blood medicine, and a cold-drug medicine;

The composition includes a head flower bud, a berberine, a leachate, a phlegm, a blood-suppressing medicine, a digestive medicine;

The composition includes a head flower bud, a berberine, a leachhin, a sputum medicinal medicine, a cooling blood hemostasis, and a remedy;

The composition includes a flower bud, a berberine, a leachate, a phlegm, a phlegm, a phlegm, and a phlegm;

The composition includes a head flower bud, a berberine, a leachhin, a phlegm, a phlegm, and a phlegm;

The composition includes a head flower bud, a berberine, a leachhin, a phlegm, a phlegm, and a remedy;

The composition includes a flower bud, a berberine, a leachate, a phlegm, a yang medicine, a medicinal agent;

The composition includes a flower bud, a berberine, a leachate, a phlegm, a stagnation medicine, a stagnation medicine, and a remedy;

The composition includes a flower bud, a berberine, a leachate, a sputum, a digestive, and a remedy;

The composition includes a head flower bud, a berberine, a water-wetting agent, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm;

The composition includes a flower bud, a berberine, a water-wetting drug, a blood-activating phlegm, a blood-suppressing hemostatic agent, and a warm-yang dispersing drug;

The composition includes a flower bud, a berberine, a water-wetting drug, a blood-activating phlegm, a blood-suppressing hemostatic agent, and a digestive drug;

The composition includes a head flower bud, a berberine, a water-wetting drug, a blood-activating phlegm, a cooling blood-stopping drug, and a solution;

The composition includes a head flower bud, a berberine, a water-wetting agent, a blood-activating phlegm, a phlegm-dampening phlegm, and a warm-yang chilling agent;

The composition includes a flower bud, a berberine, a leachhin, a blood stasis drug, a phlegm and blood stasis drug, and a digestive drug;

The composition includes a flower bud, a berberine, a leachhin, a blood stasis, a phlegm, and a remedy;

The composition includes a head flower bud, a berberine, a water-wetting agent, a blood-activating phlegm, a warm-yang dispersing medicine, and a digestive medicine;

The composition includes a head flower bud, a berberine, a water-wetting agent, a blood-activating phlegm, a warm-yang dispersing medicine, and a remedy;

The composition includes a head flower bud, a berberine, a water-wetting agent, a blood-activating phlegm, an anti-drug, and a solution;

The composition includes a head flower bud, a berberine, a water-wetting drug, a blood-suppressing hemostatic agent, a phlegm-dampening phlegm medicine, and a warm-yang dispersing medicine;

The composition includes a flower bud, a berberine, a leachhin, a blood-suppressing hemostatic agent, a phlegm-dampening phlegm, and a digestive;

The composition includes a flower bud, a berberine, a leachhin, a blood-suppressing hemostatic agent, a phlegm-dampening phlegm, and a remedy;

The composition includes a head flower bud, a berberine, a water-wetting agent, a cooling blood-stopping agent, a warm-yang dispersing medicine, and a digestive medicine;

The composition includes a head flower bud, a berberine, a water-wetting agent, a cooling blood-stopping agent, a warm-yang dispersing medicine, and a solution;

The composition includes a head flower bud, a berberine, a leachhin, a cooling blood hemostasis, a digestive medicine, and a solution;

The composition includes a head flower bud, a berberine, a water-wetting agent, a phlegm-dampening phlegm, a warm-yang dispersing medicine, and a digestive medicine;

The composition includes a head flower bud, a berberine, a water-wetting agent, a phlegm-dampening phlegm, a warm-yang dispersing medicine, and a remedy;

The composition includes a flower bud, a berberine, a leachhin, a phlegm-dampening phlegm, an anti-drug, and a remedy;

The composition includes a flower bud, a berberine, a leachhin, a warming and dispelling medicine, a digestion drug, and a solution;

The composition includes a head flower bud, a berberine, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a phlegm and blood stasis medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a sputum medicinal medicine, a blood circulation phlegm medicine, and a warm yang medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, and a digestion medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, and a remedy medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a sputum medicine, a cooling blood hemostatic medicine, a phlegm and blood stasis medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a sputum medicine, a cooling blood hemostasis, a warm and cold medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a sputum medicine, a cooling blood hemostatic medicine, a digestion medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a sputum medicine, a cooling blood hemostatic medicine, and a solution medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a phlegm medicine, a phlegm-dampening phlegm medicine, and a warm-yang dispersing medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a phlegm medicine, a phlegm-dampening phlegm medicine, and a digestion medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a phlegm medicine, a phlegm phlegm medicine, and a remedy medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a sputum medicine, a warming and dispelling medicine, and a digestive medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a sputum medicine, a yangyang cold medicine, a solution medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a sputum medicine, a digestion medicine, a solution medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a phlegm and blood stasis medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a blood circulation phlegm medicine, a cooling blood hemostasis medicine, a warm and cold medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a blood circulation phlegm medicine, a cooling blood hemostasis medicine, and a digestion medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a solution medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a blood circulation phlegm medicine, a phlegm dampness phlegm medicine, and a warm yang medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a blood circulation phlegm medicine, a phlegm phlegm medicine, and a digestion medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a blood circulation phlegm medicine, a phlegm phlegm medicine, and a remedy medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a blood circulation phlegm medicine, a warm yang medicine, and a digestion medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a blood circulation phlegm medicine, a Wenyang cold medicine, a solution medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a blood circulation phlegm medicine, a digestion medicine, a solution medicine;

The composition includes a flower bud, a berberine, a qi medicine, a cooling blood hemostasis, a phlegm and blood stasis medicine, and a warming and dispelling medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a cooling blood hemostasis, a phlegm and blood stasis medicine, and a digestive medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a cooling blood hemostasis, a phlegm phlegm, and a remedy;

The composition includes a flower bud, a berberine, a qi medicine, a cooling blood hemostasis, a warming and dispelling cold medicine, and a digestive medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a cooling blood hemostasis, a warming and dispelling cold medicine, and a solution medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a cooling blood hemostasis, a digestion medicine, a solution medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a phlegm-dampening phlegm, a warm-yang dispersing medicine, and a digestive medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a phlegm and blood stasis medicine, a Wenyang cold medicine, and a solution medicine;

The composition includes a head flower bud, a berberine, a qi medicine, a phlegm-dampening phlegm, an anti-drug, and a solution;

The composition includes a head flower bud, a berberine, a qi medicine, a yangyang cold medicine, a digestion medicine, and a solution medicine;

The composition includes a head flower bud, a berberine, a sputum medicinal herb, a blood circulation phlegm drug, a cooling blood hemostasis drug, and a phlegm and blood stasis drug;

The composition includes a head flower bud, a berberine, a sputum medicinal herb, a blood circulation phlegm medicine, a cooling blood hemostasis drug, and a warming and dissipating cold medicine;

The composition includes a flower bud, a berberine, a sputum medicinal herb, a blood circulation phlegm medicine, a cooling blood hemostasis drug, and a digestion drug;

The composition includes a head flower bud, a berberine, a sputum medicinal herb, a blood circulation phlegm medicine, a cooling blood hemostatic drug, and a remedy drug;

The composition includes a flower bud, a berberine, a sputum medicinal herb, a blood stasis phlegm, a phlegm phlegm, a phlegm and blood stasis drug;

The composition includes a flower bud, a berberine, a phlegm, a blood stasis, a phlegm, and a phlegm;

The composition includes a head flower bud, a berberine, a phlegm, a blood stasis, a phlegm, and a remedy;

The composition includes a flower bud, a berberine, a sputum medicinal herb, a blood stasis phlegm, a warming yang medicine, and a digestive medicinal agent;

The composition includes a flower bud, a berberine, a phlegm, a blood stasis, a warming and dispelling cold medicine, and a remedy;

The composition includes a flower bud, a berberine, a phlegm, a blood stasis, a digestive, and a remedy;

The composition includes a flower bud, a berberine, a phlegm, a blood-suppressing hemostatic agent, a phlegm-dampening phlegm, and a warming and dispelling cold medicine;

The composition includes a flower bud, a berberine, a phlegm, a blood-suppressing hemostatic agent, a phlegm-dampening phlegm, and a digestive;

The composition includes a flower bud, a berberine, a phlegm, a blood-suppressing hemostatic agent, a phlegm-dampening phlegm, and a remedy;

The composition includes a head flower bud, a berberine, a sputum medicinal medicine, a cooling blood stopping medicine, a warming and dispelling cold medicine, and a digestive medicine;

The composition includes a head flower bud, a berberine, a sputum medicinal medicine, a cooling blood stopping medicine, a warming and dispelling cold medicine, and a solution medicine;

The composition includes a head flower bud, a berberine, a phlegm, a blood-suppressing hemostatic, a digestive, and a remedy;

The composition includes a head flower bud, a berberine, a phlegm, a phlegm, a phlegm, a phlegm, a phlegm, and a medicinal agent;

The composition includes a flower bud, a berberine, a phlegm, a phlegm, a phlegm, a phlegm, and a remedy;

The composition includes a head flower bud, a berberine, a phlegm, a phlegm, a phlegm, a digestive, and a remedy;

The composition includes a flower bud, a berberine, a sputum medicinal herb, a stagnation medicinal herb, a digestive medicinal drug, and a remedy drug;

The composition includes a head flower bud, a berberine, a blood circulation phlegm, a cooling blood hemostasis, a phlegm and blood stasis medicine, and a warming and dispelling cold medicine;

The composition includes a head flower bud, a berberine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a phlegm and blood stasis medicine, and a digestion medicine;

The composition includes a head flower bud, a berberine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a phlegm and blood stasis medicine, and a remedy medicine;

The composition includes a flower bud, a berberine, a blood circulation phlegm, a cooling blood hemostasis, a warming and dispelling cold medicine, and a digestive medicine;

The composition includes a flower bud, a berberine, a blood circulation phlegm, a blood circulation hemostasis, a warming and dispelling cold medicine, and a remedy;

The composition includes a head flower bud, a berberine, a blood circulation phlegm medicine, a cooling blood hemostasis medicine, a digestion medicine, a solution medicine;

The composition includes a flower bud, a berberine, a blood stasis phlegm, a phlegm and blood stasis medicine, a warming and dispelling cold medicine, and a digestion medicine;

The composition includes a flower bud, a berberine, a blood stasis phlegm, a phlegm phlegm, a phlegm medicine, and a remedy;

The composition includes a flower bud, a berberine, a blood stasis, a phlegm, a phlegm, a digestive, and a remedy;

The composition includes a head flower bud, a berberine, a blood circulation phlegm medicine, a yangyang cold medicine, a digestion medicine, a solution medicine;

The composition includes a flower bud, a berberine, a blood-suppressing hemostatic agent, a phlegm-dampening phlegm, a warming and dispelling cold medicine, and a digestive medicine;

The composition includes a flower bud, a berberine, a blood-suppressing hemostatic agent, a phlegm-dampening phlegm, a warm-yang dispersing medicine, and a remedy;

The composition includes a flower bud, a berberine, a blood-suppressing hemostatic agent, a phlegm-dampening phlegm, an anti-drug, and a remedy;

The composition includes a head flower bud, a berberine, a cooling blood hemostasis, a warming and dispelling cold medicine, a digestion medicine, and a solution medicine;

The composition includes a flower bud, a berberine, a phlegm, a phlegm, a phlegm, a phlegm, a remedy, a drug, and a remedy.
The composition according to claim 12, characterized in that

The composition comprises a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a qi medicine, a blood circulation medicine, and the medicine is selected from the group consisting of:

(1) 20-60 parts by weight of head flower, 2-6 parts by weight of berberine, 10-15 parts by weight of dandelion, 9-30 parts by weight of astragalus, 6-15 parts by weight of white peony, 2-6 parts by weight of licorice, ginseng 3 -9 parts by weight, 5-10 parts by weight of perilla stem, 3-10 weight of Corydalis Volume

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a phlegm-dampening phlegm medicine, and a warm-yang chilling medicine selected from the group consisting of:

(1) 20-60 parts by weight of head flower, 2-6 parts by weight of berberine, 3-10 parts by weight of scutellaria, 3-9 parts by weight of ginseng, 2-6 parts by weight of licorice, 6-15 parts by weight of jujube, Pinellia 3-9 parts by weight, 3-10 parts by weight of dried ginger;

The composition comprising the group consisting of the head flower bud, the berberine, the tonic medicine, the water-wetting agent, the medicine, and the medicine is selected from any one of the following groups:

(1) 20-60 parts by weight of the head flower, 2-6 parts by weight of Rhizoma Coptidis, 9-18 parts by weight of Codonopsis pilosula, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, and 8-12 parts by weight of Schisandra chinensis;

(2) 20-60 parts by weight of the head flower, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, 8-12 parts by weight of Schisandra;

(3) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, 9-18 parts by weight of Codonopsis pilosula, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, and schisandra 8- 12 parts by weight.
The composition according to claim 3, wherein said composition consists of any of the five classes of drugs of the first eleven types of medicinal properties;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, and a sputum medicine;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a blood-activating phlegm;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a cooling blood hemostatic medicine;

The composition includes a flower bud, a coptis, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, and a phlegm-dampening phlegm;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, and a warm-yang dispersing drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a gas-making drug, and a digestion drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, and a solution medicine;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a phlegm-receiving drug, a blood-activating phlegm drug;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting agent, a phlegm-receiving medicine, a cooling blood-stopping medicine;

The composition includes a flower bud, a coptis, a heat-clearing drug, a tonic drug, a water-wetting drug, a phlegm-receiving drug, and a phlegm-dampening phlegm;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a phlegm-receiving drug, and a warm-yang dispersing drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a phlegm-receiving drug, and a digestive drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a phlegm-receiving drug, and a remedy drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a blood-activating phlegm drug, and a cooling blood-stopping drug;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a blood-activating phlegm drug, and a phlegm-dampening phlegm;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a blood-activating phlegm, and a warm-yang dispersing drug;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a blood-activating phlegm drug, and a digestion-eliminating drug;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a blood-activating phlegm drug, and a remedy drug;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a cooling blood-stopping drug, and a dampness Peony

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a cooling blood-stopping drug, and a warm-yang dispersing drug;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a cooling blood-stopping drug, and a digestion-eliminating drug;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a cooling blood-stopping drug, and a solution-solving drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a phlegm-dampening phlegm, and a warm-yang dispersing drug;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a phlegm-dampening phlegm, and a digestion-eliminating drug;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a phlegm-dampening phlegm, and a remedy;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a warm-yang dispersing drug, and a digestive drug;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting agent, a warm-yang dispersing medicine, and a solution medicine;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a digestion drug, and a solution;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a qi medicine, a sputum medicine, a cooling blood hemostasis;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, a qi medicine, a phlegm medicine, and a phlegm-dampening phlegm;

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, and a warm-yang medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting agent, a qi medicine, a sputum medicine, and a digestion medicine;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a qi medicine, a sputum medicine, and a solution medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, a qi medicine, a blood circulation phlegm medicine, and a phlegm-dampening phlegm;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a qi medicine, a blood-activating phlegm medicine, and a warm-yang dispersing medicine;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, a qi medicine, a blood circulation phlegm medicine, and a digestion medicine;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, a qi medicine, a blood-activating phlegm medicine, and a solution medicine;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a qi medicine, a cooling blood hemostasis, and a phlegm-dampening phlegm;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, a qi medicine, a cooling blood hemostasis, and a warm-yang dispersing medicine;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a qi medicine, a cooling blood hemostasis drug, and a digestion drug;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a qi medicine, a cooling blood hemostasis, and a solution;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a qi medicine, a phlegm-dampening phlegm medicine, and a warm-yang dispersing medicine;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, a qi medicine, a phlegm-dampening phlegm medicine, and a digestion-reducing medicine;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a qi medicine, a phlegm-dampening phlegm, and a remedy;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a qi medicine, a warm-yang dispersing medicine, and a digestive medicine;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, a qi medicine, a warm-yang dispersing medicine, and a solution medicine;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting agent, a qi medicine, a digestion medicine, and a solution medicine.
The composition according to claim 14 wherein

The composition comprising the group consisting of the head flower bud, the berberine, the tonic medicine, the leachate, the qi medicine, the blood circulation phlegm medicine, and the phlegm phlegm medicine is selected from any one of the following groups:

(1) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, 9-15 parts by weight of medlar, 5-10 parts of dried tangerine peel Parts by weight, 3-10 parts by weight of Corydalis, 3-9 parts by weight of Pinellia ternata;

(2) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, 9-18 parts by weight of Codonopsis pilosula, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, 10-15 parts by weight of Salvia miltiorrhiza, and Magnolia 3 -10 parts by weight;

The composition comprising the head flower bud, the berberine, the tonic medicine, the water-wetting agent, the qi medicine, the blood circulation phlegm medicine, and the solution medicine are selected from any one of the following groups:

(1) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, 3-10 parts by weight of Corydalis, cassia twig 3 -10 parts by weight;

(2) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, 9-18 parts by weight of Codonopsis pilosula, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, 10-15 parts by weight of Salvia miltiorrhiza, Bupleurum 3 - 10 parts by weight.
A composition according to claim 3, wherein said composition consists of any of the six classes of drugs of the first eleven types of medicinal properties;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a phlegm medicine, and a blood-suppressing medicine;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a sputum medicine, and a phlegm-dampening phlegm;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a sputum medicine, and a warm-yang medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, and a digestion medicine;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a sputum medicine, and a solution medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi-drug, a blood-activating phlegm, and a phlegm-relieving phlegm;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a blood-activating phlegm medicine, and a warm-yang dispersing medicine;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a blood-activating phlegm medicine, and a digestion-reducing medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting agent, a qi medicine, a blood-activating phlegm medicine, and a remedy medicine;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a cooling blood-stopping drug, and a phlegm-dampening phlegm;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a cooling blood-stopping drug, and a warm-yang dispersing drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a cooling blood hemostasis drug, and a digestion drug;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a cooling blood hemostatic medicine, and a solution medicine;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi-drug, a phlegm-dampening phlegm, and a warm-yang dispersing drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a phlegm-dampening phlegm medicine, and a digestion-reducing medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a phlegm-dampening phlegm medicine, and a remedy medicine;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a warm-yang dispersing medicine, and a digestive medicine;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a warm-yang powder medicine, and a solution medicine;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a digestion medicine, and a solution medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a phlegm-dampening phlegm medicine;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a qi medicine, a sputum medicine, a blood-activating phlegm medicine, and a warm-yang medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, and a digestion medicine;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, and a remedy medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a phlegm medicine, a blood-suppressing medicine, and a phlegm-dampening medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a cooling blood hemostasis, a warm-yang powder medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a cooling blood hemostatic medicine, a digestion medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a cooling blood hemostatic medicine, a solution medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a phlegm medicine, a phlegm-dampening phlegm medicine, and a warm-yang dispersing medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a phlegm medicine, a phlegm-dampening phlegm medicine, and a food-removing medicine;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a qi medicine, a phlegm medicine, a phlegm-dampening phlegm, and a solution. Table drug

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a qi medicine, a sputum medicine, a Wenyang cold medicine, and a digestion medicine;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a qi medicine, a sputum medicine, a Wenyang cold medicine, a solution medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting agent, a qi medicine, a sputum medicine, a digestion medicine, and a remedy medicine.
The composition according to claim 16 wherein

The composition comprising the group consisting of the head flower bud, the berberine, the tonic medicine, the water-wetting drug, the qi medicine, the phlegm medicine, the Wenyang cold medicine, and the solution medicine is selected from any one of the following groups:

(1) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, 9-18 parts by weight of Codonopsis pilosula, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, 8-12 parts by weight of Schisandra chinensis, Wujing 2- 5 parts by weight, Bupleurum 3-10 parts by weight;

(2) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, 8-12 parts by weight of schisandra, galangal 3 -6 parts by weight, cassia twig 3-10 parts by weight.
The composition according to claim 3, wherein said composition consists of any of the seven classes of drugs of the first eleven types of medicinal properties;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a phlegm-dampening phlegm medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood-activating phlegm medicine, and a warm-yang medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, and a digestion medicine;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, and a remedy medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a phlegm medicine, a blood-suppressing medicine, and a phlegm-dampening medicine;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a phlegm medicine, a blood-suppressing medicine, and a warm-yang medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a cooling blood hemostasis medicine, and a digestion medicine;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a sputum medicine, a cooling blood hemostatic medicine, and a solution medicine;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a phlegm medicine, a phlegm-dampening phlegm medicine, and a warm-yang dispersing medicine;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a phlegm-receiving medicine, a phlegm-dampening phlegm medicine, and a digestive medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a phlegm medicine, a phlegm-dampening phlegm medicine, and a remedy medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a warm-yang powder medicine, and a digestion medicine;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a sputum medicine, a Wenyang cold medicine, and a solution medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a digestion medicine, and a prescription medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a phlegm and blood stasis medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicinal medicine, a blood circulation phlegm medicine, a cooling blood hemostasis medicine, a Wenyang cold medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostasis medicine, and a digestion medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a solution medicine;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a qi medicine, a phlegm-removing medicine, a blood-activating phlegm medicine, a phlegm-dampening phlegm medicine, and a warm-yang dispersing medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a phlegm-dampening phlegm medicine, and a digestion medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a phlegm-dampening phlegm medicine, and a remedy medicine;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a qi medicine, a sputum medicinal medicine, a blood-activating phlegm medicine, a warm-yang dispersing medicine, and a digestive medicine;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a qi medicine, a sputum medicinal medicine, a blood-activating phlegm medicine, a warm-yang dispersing medicine, and a remedy medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting agent, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a digestion medicine, and a remedy medicine.
The composition according to claim 18, characterized in that

The composition comprising the head flower bud, the berberine, the tonic medicine, the diarrhea phlegm, the qi medicine, the phlegm medicine, the blood circulation phlegm medicine, the phlegm phlegm medicine, the Wenyang chilling medicine group is selected from any of the following A group:

(1) 20-60 parts by weight of head flower buds, 2-6 parts by weight of Rhizoma coptidis, 9-18 parts by weight of Codonopsis pilosula, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, 8-12 parts by weight of Schisandra, Corydalis 3- 10 parts by weight, 3-9 parts by weight of Pinellia, 2-5 parts by weight of Wusong;

(2) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, 8-12 parts by weight of schisandra, and 10 parts by weight of Salvia miltiorrhiza 15 parts by weight, Magnolia 3-10 parts by weight, Galangal 3-6 parts by weight.
The composition according to claim 3, wherein said composition consists of a flower bud, a berberine, and the above eleventh Composition of any of the eight classes of drugs;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a phlegm-removing medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, and a phlegm-dampening phlegm;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi-drug, a phlegm-removing drug, a blood-activating phlegm drug, a cooling blood-stopping drug, and a warm-yang dispersing drug;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostasis medicine, and a digestion medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, and a remedy medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a phlegm-removing medicine, a blood-activating phlegm medicine, a phlegm-dampening phlegm medicine, and a warm-yang dispersing medicine;

The composition includes a head flower bud, a coptis, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a phlegm-removing medicine, a blood-activating phlegm medicine, a phlegm-dampening phlegm medicine, and a digestion-reducing medicine;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a phlegm-removing medicine, a blood-activating phlegm medicine, a phlegm-dampening phlegm medicine, and a remedy medicine;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a phlegm-removing medicine, a blood-activating phlegm medicine, a warm-yang dispersing medicine, and a digestion-reducing medicine;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a phlegm-removing medicine, a blood-activating phlegm medicine, a warm-yang dispersing medicine, and a remedy medicine;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a digestion medicine, a solution medicine;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostasis medicine, a phlegm-dampening phlegm medicine, and a warm-yang dispersing medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a phlegm-dampening phlegm medicine, and a digestion medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a phlegm-dampening phlegm medicine, and a remedy medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostasis medicine, a Wenyang cold medicine, a digestion medicine;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a Wenyang cold medicine, a solution medicine;

The composition includes a head flower bud, a berberine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a digestion medicine, and a solution medicine.
The composition according to claim 20, characterized in that

The composition described in 9.1 includes the head flower bud, berberine, tonic medicine, diarrhea phlegm, qi medicine, phlegm medicine, blood circulation phlegm medicine, cooling blood to stop bleeding medicine, phlegm and blood stasis medicine, Wenyang cold medicine The group is selected from any of the following groups:

(1) 20-60 parts by weight of head flower buds, 2-6 parts by weight of Rhizoma coptidis, 9-18 parts by weight of Codonopsis pilosula, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, 8-12 parts by weight of Schisandra, Corydalis 3- 10 parts by weight, white and 6-15 parts by weight, 3-9 parts by weight of Pinellia, Wu Hao 2-5 parts by weight;

(2) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, 8-12 parts by weight of schisandra, and 10 parts by weight of Salvia miltiorrhiza 15 parts by weight, white and 6-15 parts by weight, Magnolia 3-10 parts by weight, and Galangal 3-6 parts by weight.
The composition according to claim 3, wherein said composition consists of any of nine drugs of the first eleven types of medicinal properties;

The composition includes a head flower bud, a berberine, a leachhin, a qi medicine, a sputum medicinal medicine, a blood circulation phlegm medicine, a blood circulation hemostasis medicine, a phlegm and blood stasis medicine, a yangyang cold medicine, a digestion medicine, Solution medicine

The composition includes the head flower bud, berberine, tonic medicine, qi medicine, phlegm medicine, blood circulation phlegm medicine, cooling blood hemostasis medicine, phlegm and blood stasis medicine, Wenyang cold medicine, digestion medicine, solution table medicine;

The composition includes a head flower bud, a berberine, a tonic drug, a water-wetting drug, a phlegm-removing drug, a blood-activating phlegm drug, a cooling blood-stopping medicinal agent, a phlegm-dampening phlegm drug, a yang-yang medicinal drug, a digestion drug, and a solution. Table drug

The composition includes the head flower bud, berberine, tonic medicine, diarrhea dialysis medicine, qi medicine, blood circulation phlegm medicine, cooling blood hemostasis medicine, phlegm and blood stasis medicine, Wenyang cold medicine, digestion medicine, solution Table drug

The composition includes the head flower bud, berberine, tonic medicine, diarrhea phlegm, qi medicine, phlegm medicine, cooling blood to stop bleeding medicine, phlegm and blood stasis medicine, Wenyang cold medicine, digestion medicine, solution table medicine;

The composition includes the head flower bud, berberine, tonic medicine, diarrhea phlegm, qi medicine, phlegm medicine, blood circulation phlegm medicine, phlegm and blood stasis medicine, Wenyang cold medicine, digestion medicine, solution table medicine;

The composition includes the head flower bud, berberine, tonic medicine, diarrhea phlegm, qi medicine, phlegm medicine, blood circulation phlegm medicine, cooling blood hemostasis medicine, Wenyang cold medicine, digestion medicine, solution medicine ;

The composition includes the head flower bud, berberine, tonic medicine, diarrhea phlegm, qi medicine, phlegm medicine, blood circulation phlegm medicine, cooling blood hemostasis medicine, phlegm and blood stasis medicine, digestion medicine, solution medicine ;

The composition includes a head flower bud, a beryl, a tonifying agent, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a phlegm-dampening phlegm medicine, a yang yang medicine, Solution medicine

The composition includes a head flower bud, a beryl, a tonifying agent, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a phlegm-dampening phlegm medicine, a yang yang medicine, Digestive medicine;

The composition includes the head flower bud, berberine, heat-clearing medicine, qi medicine, phlegm medicine, blood circulation phlegm medicine, cooling blood hemostasis medicine, phlegm and blood stasis medicine, Wenyang cold medicine, digestion medicine, solution Table drug

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a phlegm-removing drug, a blood-activating phlegm drug, a cooling blood-stopping medicinal agent, a phlegm-dampening phlegm drug, a warm-yang dispelling medicinal agent, a digestive medicinal drug, Solution medicine

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a water-wetting drug, a qi medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, a warm-yang dispersing medicine, a digestion medicine, Solution medicine

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a qi medicine, a sputum medicine, a blood-suppressing blood-suppressing medicine, a phlegm-dampening phlegm medicine, a warm-yang dispersing medicine, a digestion medicine, and a solution. Table drug

The composition includes a flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a qi medicine, a phlegm-removing medicine, a blood-activating phlegm medicine, a phlegm-dampening phlegm medicine, a warm-yang dispersing medicine, a digestion medicine, and a solution. Table drug

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a qi medicine, a sputum medicinal medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a warm-yang dispersing medicine, a digestion medicine, and a solution table. medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a phlegm-dampening phlegm medicine, a digestion medicine, and a solution table. medicine;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a qi medicine, a sputum medicinal medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, and a warm-yang dispersing medicine. , to solve the drug;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a qi medicine, a sputum medicinal medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, and a warm-yang dispersing medicine. And digestive drugs;

The composition includes a flower bud, a peony root, a heat-clearing drug, a tonic drug, a phlegm-removing drug, a blood-activating phlegm drug, a cooling blood-stopping medicinal agent, a phlegm-dampening phlegm drug, a yang-yang medicinal drug, a food-disinfecting drug, and a solution table. medicine;

The composition includes the head flower bud, berberine, heat-clearing medicine, tonic medicine, qi medicine, blood circulation phlegm medicine, cooling blood hemostasis medicine, phlegm and blood stasis medicine, Wenyang cold medicine, digestion medicine, solution table medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a qi medicine, a sputum medicine, a cooling blood hemostasis medicine, a phlegm-dampening phlegm medicine, a Wenyang cold medicine, a digestion medicine, and a remedy medicine. ;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a phlegm-dampening phlegm medicine, a warm-yang dispersing medicine, a digestion medicine, and a remedy medicine. ;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a Wenyang cold medicine, a digestion medicine, a solution medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a phlegm-dampening phlegm medicine, a digestion medicine, and a remedy medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a phlegm-dampening phlegm medicine, a yang-yang medicine, a solution Table drug

The composition includes the head flower bud, berberine, heat-clearing medicine, tonic medicine, qi medicine, phlegm medicine, blood circulation phlegm medicine, cooling blood hemostatic medicine, phlegm and blood stasis medicine, Wenyang cold medicine, digestion medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, a warm-yang dispersing medicine, a digestion medicine, and a solution. Table drug

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a phlegm-receiving medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, a warm-yang dispersing medicine, a digestion medicine, and a solution table. medicine;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a phlegm-removing drug, a blood-activating phlegm drug, a phlegm-dampening phlegm drug, a warm-yang dispersing drug, a digestion drug, and a solution table. medicine;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a phlegm-removing drug, a blood-activating phlegm drug, a cooling blood-stopping drug, a warm-yang dispersing drug, a digestive drug, and a remedy drug. ;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a phlegm-removing medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, a digestion medicine, and a remedy medicine. ;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a phlegm-removing medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, a warm-yang dispersing medicine, Solution medicine

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a phlegm-removing medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, a warm-yang dispersing medicine, Digestive medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, a warm-yang dispersing medicine, a digestion medicine, and a solution table. medicine;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a blood circulation Peony, phlegm and phlegm, phlegm and blood stasis, anti-drug, and remedy;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a warm-yang dispersing medicine, a digestion medicine, and a solution medicine. ;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, a digestion medicine, and a remedy medicine. ;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, a warm-yang dispelling medicine, Solution medicine

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, a warm-yang dispelling medicine, Digestive medicine;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a phlegm-receiving medicinal agent, a phlegm-dampening phlegm drug, a yang-yang medicinal drug, a digestive medicinal drug, and a remedy drug. ;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a sputum medicine, a cooling blood-stopping medicine, a Wenyang cold medicine, a digestion medicine, and a prescription medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, a digestion medicine, and a remedy medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, a warm-yang dispelling medicine, and a solution. Table drug

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, a warm-yang dispersing medicine, and a digestion. medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood-activating phlegm medicine, a Wenyang cold medicine, a digestion medicine, and a prescription medicine;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a phlegm-removing medicine, a blood-activating phlegm medicine, a phlegm-dampening phlegm medicine, a digestion medicine, and a remedy medicine;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a phlegm-removing medicine, a blood-activating phlegm medicine, a phlegm-dampening phlegm medicine, a warm-yang dispelling medicine, and a solution. Table drug

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood-activating phlegm medicine, a phlegm-dampening phlegm medicine, a warm-yang dispersing medicine, and a digestion medicine;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a sputum-removing medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a digestion medicine, and a remedy medicine;

The composition includes a flower bud, a berberine, a heat-clearing drug, a tonic drug, a water-wetting drug, a qi medicine, a phlegm-removing medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a warm-yang dispersing medicine, and a solution table. medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a warm-yang medicine, and a food-eliminating medicine. ;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a phlegm-removing medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, and a solution table. medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, a digestion medicine. ;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, and a yang-yang Dispel cold medicine.
The composition according to claim 22, characterized in that

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, and a yang-yang The group of cold medicine and solution medicine is selected from any one of the following groups:

(1) 20-60 parts by weight of head flower buds, 2-6 parts by weight of Rhizoma coptidis, 9-18 parts by weight of Codonopsis pilosula, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, 8-12 parts by weight of Schisandra, Corydalis 3- 10 parts by weight, white and 6-15 parts by weight, 3-9 parts by weight of Pinellia, 2-5 parts by weight of Evodia, 3-10 parts by weight of Bupleurum;

(2) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, 8-12 parts by weight of schisandra, and 10 parts by weight of Salvia miltiorrhiza 15 parts by weight, white and 6-15 parts by weight, Magnolia 3-10 parts by weight, Galangal 3-6 parts by weight, and Guizhi 3-10 parts by weight.
The composition according to claim 3, wherein said composition consists of any of the tenth class of drugs of the first eleven types of medicinal properties;

The composition includes a head flower bud, a beryl, a tonifying agent, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a phlegm-dampening phlegm medicine, a yang yang medicine, Subsistence medicine, solution medicine;

The composition includes a head flower bud, a berberine, a heat-clearing drug, a water-wetting drug, a qi medicine, a sputum medicinal medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, and a warm-yang dispersing medicine. , digestion drugs, solution drugs;

The composition includes the head flower bud, berberine, heat-clearing medicine, tonic medicine, qi medicine, phlegm medicine, blood circulation phlegm medicine, cooling blood hemostatic medicine, phlegm and blood stasis medicine, Wenyang cold medicine, digestion Medicine, drug solution;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a phlegm-removing medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, a warm-yang dispersing medicine, Subsistence medicine, solution medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, a warm-yang dispelling medicine, Subsistence medicine, solution medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, a warm-yang dispersing medicine, and a digestion. Medicine, drug solution;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood-activating phlegm medicine, a phlegm-dampening phlegm medicine, a warm-yang dispersing medicine, and a digestion Medicine, drug solution;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a warm-yang medicine, and a food-eliminating medicine. , to solve the drug;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, a digestion medicine. , to solve the drug;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, and a yang-yang Dispelling cold medicine, solution medicine;

The composition includes a head flower bud, a berberine, a heat-clearing medicine, a tonic medicine, a water-wetting drug, a qi medicine, a sputum medicine, a blood-activating phlegm medicine, a cooling blood-stopping medicine, a phlegm-dampening phlegm medicine, and a yang-yang Dispel cold medicine, digestion medicine.
The composition according to claim 24, characterized in that

The composition includes a head flower bud, a beryl, a tonifying agent, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a phlegm-dampening phlegm medicine, a yang yang medicine, The group of digestion drugs is selected from any of the following groups:

(1) 20-60 parts by weight of head flower buds, 2-6 parts by weight of Rhizoma coptidis, 9-18 parts by weight of Codonopsis pilosula, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, 8-12 parts by weight of Schisandra, Corydalis 3- 10 parts by weight, white and 6-15 parts by weight, 3-9 parts by weight of Pinellia, 2-5 parts by weight of Evodia, 9-12 parts by weight of Hawthorn;

(2) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, 8-12 parts by weight of schisandra, and 10 parts by weight of Salvia miltiorrhiza 15 parts by weight, white and 6-15 parts by weight, magnolia 3-10 parts by weight, galangal 3-6 parts by weight, hawthorn 9-12 parts by weight;

The composition includes the head flower bud, berberine, tonic medicine, diarrhea phlegm, qi medicine, phlegm medicine, blood circulation phlegm medicine, cooling blood hemostasis medicine, Wenyang cold medicine, digestion medicine, solution medicine The group is selected from any of the following groups:

(1) 20-60 parts by weight of head flower buds, 2-6 parts by weight of Rhizoma coptidis, 9-18 parts by weight of Codonopsis pilosula, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, 8-12 parts by weight of Schisandra, Corydalis 3- 10 parts by weight, white and 6-15 parts by weight, 2-5 parts by weight of Evodia, 9-12 parts by weight of hawthorn, 3-10 parts by weight of Bupleurum;

(2) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, 8-12 parts by weight of schisandra, and 10 parts by weight of Salvia miltiorrhiza 15 parts by weight, white and 6-15 parts by weight, galangal 3-6 parts by weight, hawthorn 9-12 parts by weight, and cassia twig 3-10 parts by weight.
The composition according to claim 3, wherein said composition consists of any of eleven drugs of the first ten types of medicinal properties;

The composition includes a head flower bud, a beryl, a tonifying agent, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a phlegm-dampening phlegm medicine, a yang yang medicine, Digestive medicine, solution medicine.
The composition according to claim 26, characterized in that

The composition includes a head flower bud, a beryl, a tonifying agent, a water-wetting drug, a qi medicine, a sputum medicine, a blood circulation phlegm medicine, a cooling blood hemostatic medicine, a phlegm-dampening phlegm medicine, a yang yang medicine, The group of digestion drugs and drug-solving drugs are selected from any one of the following groups:

(1) 20-60 parts by weight of head flower buds, 2-6 parts by weight of Rhizoma coptidis, 9-18 parts by weight of Codonopsis pilosula, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, 8-12 parts by weight of Schisandra, Corydalis 3- 10 parts by weight, white and 6-15 parts by weight, 3-9 parts by weight of Pinellia, 2-5 parts by weight of Evodia, 9-12 parts by weight of hawthorn, 3-10 parts by weight of Bupleurum;

(2) 20-60 parts by weight of head flower buds, 2-6 parts by weight of berberine, 4-9 parts by weight of licorice, 9-15 parts by weight of medlar, 5-10 parts by weight of dried tangerine peel, 8-12 parts by weight of schisandra, and 10 parts by weight of Salvia miltiorrhiza 15 parts by weight, white and 6-15 parts by weight, Magnolia 3-10 parts by weight, Galangal 3-6 parts by weight, Hawthorn 9-12 parts by weight, and Guizhi 3-10 parts by weight.
A pharmaceutical composition according to any one of claims 1 to 27, further comprising one or more other drugs selected from the group consisting of: an antimicrobial agent, a proton pump inhibitor, a gastric mucosal protectant, an antacid, H 2 receptor antagonist.
The composition according to claim 28, characterized in that

The antimicrobial agent is selected from the group consisting of penicillins such as amoxicillin, macrolides such as clarithromycin, and nitrazoles such as metronidazole.

The proton pump inhibitor is selected from the group consisting of omeprazole, lansoprazole and pantoprazole.

The gastric mucosal protective agent is selected from the group consisting of sucralfate and smecta

The antacid, such as a magnesium hydroxide mixture

The H 2 receptor antagonists, such as cimetidine, ranitidine, famotidine.
A method for preparing a pharmaceutical composition extract, characterized in that the method is selected from any one or more of the following:

(1-1) The pharmaceutical composition according to any one of claims 1 to 27, which is obtained by extracting an inorganic or organic solvent alone or in a mixed solvent;

(1-2) The pharmaceutical composition according to any one of claims 1 to 27, which is obtained by extracting and mixing two or more mixed solvents of water and ethanol, acetone and ethyl acetate;

(1-3) The pharmaceutical composition according to any one of claims 1 to 27 is obtained by solvent extraction with 5 to 30 times of water;

(1-4) The pharmaceutical composition according to any one of claims 1 to 27, which is obtained by extracting and obtaining 5-30 times of 30-99% of a lower alcohol (C1-C5), acetone, acetic acid solution;

(1-5) The pharmaceutical composition according to any one of claims 1 to 27, which is obtained by extracting and obtaining 5 to 30 times of a 30 to 99% aqueous solution of ethanol as an extraction solvent;

(1-6) The pharmaceutical composition according to any one of claims 1 to 27, which is obtained by extracting 6 to 8 times of a 70% aqueous solution of ethanol as a solvent;

(1-7) The pharmaceutical composition according to any one of claims 1 to 27, which is obtained by extracting and obtaining 5 to 15 times of a mixed solvent of 5 to 95% of an alcohol and an ester;

(1-8) The pharmaceutical composition according to any one of claims 1 to 27, which is obtained by extracting and obtaining 5 to 20 times of ethyl acetate, petroleum ether and diethyl ether as an extraction solvent;

(2) Prepared according to the method comprising the following steps: the pharmaceutical composition according to any one of claims 1 to 27, decoctioned with water, ethanol, aqueous ethanol solution and / or reflux extraction, filtered and concentrated filtrate, dried;

(3) The pharmaceutical composition according to any one of claims 1 to 27 is prepared according to the method comprising the following steps: adding 5 to 30 times of water to cook, and extracting 1 to 5 times at 50 to 100 ° C for 0.5 to 5 times each time. In an hour, the extract is combined and filtered, and concentrated to a thick paste having a relative density of 1.1 to 1.5, and dried under reduced pressure;

(4) The pharmaceutical composition according to any one of claims 1 to 27 is prepared according to the method comprising the following steps: adding 6 to 8 times of water to decoct, and extracting at 85 to 100 ° C twice for 1 to 1.5 hours each time. The extract is filtered and combined, concentrated to a thick paste having a relative density of 1.2 to 1.3, and dried under reduced pressure;

(5) The pharmaceutical composition according to any one of claims 1 to 27 is prepared according to the method comprising the following steps: adding 5 to 30 times of ethanol and 30 to 99% of an aqueous ethanol solution for refluxing for 1 to 5 times, each time 0.5 to 0.5 After 5 hours, the extract is filtered and combined, concentrated to a thick paste having a relative density of 1.1 to 1.5, and dried under reduced pressure;

(6) Prepared according to the method comprising the following steps: the pharmaceutical composition according to any one of claims 1 to 27, adding 6 to 8 times of a 70% aqueous solution of ethanol, and extracting twice, each time for 1 to 1.5 hours, filtering and combining The extract is concentrated to a thick paste having a relative density of 1.2 to 1.3, and dried under reduced pressure.
The pharmaceutical composition extract prepared according to claim 30.
A pharmaceutical preparation composition comprising the pharmaceutical composition according to any one of claims 1 to 29 as an active ingredient and/or the pharmaceutical composition extract of claim 31 and a pharmaceutically acceptable adjuvant.
The pharmaceutical preparation composition according to claim 32, wherein the pharmaceutical preparation composition is an oral preparation.
A pharmaceutical composition according to claim 33, wherein said oral preparation is selected from the group consisting of various usable conventional release preparations and sustained release preparations.
The pharmaceutical composition according to claim 34, wherein said controlled release preparation is selected from the group consisting of a skeleton type, a membrane controlled type, an osmotic pump type, and a gastric retention type sustained release preparation.
The pharmaceutical composition according to Claim 35, wherein said intragastric retention-type controlled release preparation is selected from the group consisting of gastric floating agents.
Use of the pharmaceutical composition according to any one of claims 1 to 29 and/or the pharmaceutical composition extract of claim 31 for the preparation of an antibacterial drug.
The use according to claim 37, wherein said pathogen is selected from the group consisting of Gram-positive methicillin-resistant Staphylococcus aureus S. aureus (Methicllin-resistant, MRSA), methicillin-sensitive Staphylococcus aureus S. aureus (Methicin-suseptable), methicillin-resistant Staphylococcus epidermidis (MRSE), methicillin-sensitive Staphylococcus epidermidis (MSSE), also selected from Gram-negative bacteria Escherichia coli (ESBLS) Escherichia Coli, Eco + , Escherichia coli (non-ESBLS) Escherichia Coli, Eco - , Klebsiella Klebsiella (ESBLs) K. penumonia, KPN + , Klebsiella pneumonia (non-ESBLs) K. penumonia, patina Pseudomonas aeruginosa (PAE).
Use of the pharmaceutical composition according to any one of claims 1 to 29 and/or the pharmaceutical composition extract of claim 31 for the preparation of a medicament for preventing/treating Helicobacter pylori.