WO2016034976A1 - Window-based spectrum measurement in a spectral ct detector - Google Patents

Window-based spectrum measurement in a spectral ct detector Download PDF

Info

Publication number
WO2016034976A1
WO2016034976A1 PCT/IB2015/056381 IB2015056381W WO2016034976A1 WO 2016034976 A1 WO2016034976 A1 WO 2016034976A1 IB 2015056381 W IB2015056381 W IB 2015056381W WO 2016034976 A1 WO2016034976 A1 WO 2016034976A1
Authority
WO
WIPO (PCT)
Prior art keywords
comparator
reference signal
window
energy
reference signals
Prior art date
Application number
PCT/IB2015/056381
Other languages
French (fr)
Inventor
Christoph Herrmann
Original Assignee
Koninklijke Philips N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninklijke Philips N.V. filed Critical Koninklijke Philips N.V.
Priority to US15/502,788 priority Critical patent/US10788594B2/en
Priority to EP15771262.1A priority patent/EP3195017B1/en
Priority to CN201580047228.9A priority patent/CN106687825B/en
Publication of WO2016034976A1 publication Critical patent/WO2016034976A1/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01TMEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T1/00Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
    • G01T1/16Measuring radiation intensity
    • G01T1/24Measuring radiation intensity with semiconductor detectors
    • G01T1/247Detector read-out circuitry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01TMEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T1/00Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
    • G01T1/36Measuring spectral distribution of X-rays or of nuclear radiation spectrometry

Definitions

  • CT computed tomography
  • a computed tomography (CT) scanner generally includes a rotating gantry rotatably mounted to a stationary gantry.
  • the rotating gantry supports an X-ray tube and is configured to rotate around an examination region about a longitudinal or Z-axis.
  • a detector array is located opposite the X-ray tube, across the examination region.
  • the X-ray tube is configured to emit radiation that traverses the examination region (and a portion of an object or a subject therein) and impinges upon the detector array.
  • the detector array includes a one or two dimensional array of detector pixels that detect the radiation and produce signals indicative thereof. Each pixel conveys a corresponding signal for further processing.
  • a reconstructor reconstructs the signals, producing volumetric image.
  • the detector pixels can include a direct conversion material disposed between a cathode and an anode with a voltage applied across the cathode and anode. Photons strike the cathode, transferring energy to electrons in the direct conversion material, which creates electron/hole pairs, with the electrons drifting towards the anode.
  • the anode produces the electrical signals output by the detector array.
  • a pulse shaper processes the signals and produces pulses having peak heights indicative of the energy of the detected radiation.
  • a discriminator compares, with comparators, the heights with a set of energy thresholds. For each threshold, a counter counts a number of times a pulse height crosses the threshold. A binner bins the counts in energy-ranges.
  • a decomposer decomposes the binned data, e.g., into spectral components. The reconstructor reconstructs the spectral components.
  • the forward-model-based evaluation technique of measured photon-counting data requires an accurate estimate of the detector pixels' detector response, i.e., for different single excitation energies, the spectrum of absorbed energies.
  • the detector response can be obtained by differentiating a threshold scan obtained with one of the available comparators.
  • a threshold scan obtained with one of the available comparators.
  • such a measurement is highly noisy since the differentiation amplifies the inherent noise within the threshold scan data. For example, discrete differentiation implies subtraction of two statistically independent noisy Poisson random variables, so that the resulting variance equals the sum of the individual variances.
  • a window based spectrum measurement can be implemented.
  • the resulting noise is considerably reduced, at least because the number of counts within the window is much smaller than the number of counts above one of the thresholds.
  • gain mismatches between the two comparators results in window widths that vary, or will not be constant, across the range of all threshold levels. As a consequence, the measurements require significant correction, resulting in a complex measurement procedure.
  • a detector array signal processor of an imaging system includes a discriminator.
  • the discriminator includes a set of comparators, a window width generator that generates a window width for a window based spectrum measurement, and a set of reference signal generators, each corresponding to a different one of the comparators, which generate different reference signals.
  • a first reference signal generator for a first comparator generates a reference signal that is supplied to the first comparator and that is added with the window width with a result of the addition supplied to the second comparator.
  • the first comparator compares a peak height of a pulse indicative of an energy of detected radiation with the supplied reference signal and produces a first output indicating which of the peak height or the reference signal is greater.
  • the second comparator compares the peak height with the supplied result of the addition and produces a second output indicating which of the peak height or the result of the addition is greater.
  • a method in another aspect, includes receiving, sequentially, a plurality of pulses, each having a peak height indicative of an energy of different detected radiation, a window width for a window based spectrum measurement, and a set of reference signals for a first comparator.
  • the method further includes providing the pulse and, sequentially, each of the reference signals of the set to the first comparator and the pulse and, sequentially, each of the reference signals added to the window width to a second comparator.
  • the method further includes counting a first number of times a first output of the first comparator exceeds the reference signals and a second number of times a second output of the second comparator exceeds the reference signals added to the window width.
  • the method further includes determining a window based spectrum measurement for each of the different reference signals by determining a difference between the first number and the second number for the corresponding reference signals.
  • a method in another aspect, includes receiving, sequentially, a plurality of pulses, each having a peak height indicative of an energy of different detected radiation, a window width for a window based spectrum measurement, and a set of reference signals for a first comparator.
  • the method further includes providing the pulse and, sequentially, each of the reference signals of the set to the first comparator, and the pulse and, sequentially, each of the reference signals added to the window width to a second comparator.
  • the method further includes counting a first number of times a first output of the first comparator exceeds the reference signals and counting a second number of times a second output of the second comparator exceeds the reference signals added to the window width.
  • the method further includes calibrating an energy threshold of at least one of the first or the second comparators based on the window based spectrum measurements.
  • the invention may take form in various components and arrangements of components, and in various steps and arrangements of steps.
  • the drawings are only for purposes of illustrating the preferred embodiments and are not to be construed as limiting the invention.
  • FIGURE 1 schematically illustrates an example imaging system with a discriminator configured to operate in a window based spectrum measurement mode.
  • FIGURE 2 schematically illustrates an example of the discriminator in a non- window based spectrum measurement mode.
  • FIGURE 3 schematically illustrates an example of the discriminator in the window based spectrum measurement mode.
  • FIGURE 4 illustrates an example method for taking window based spectrum measurements.
  • FIGURE 5 schematically illustrates an example of the discriminator with N comparators.
  • FIGURE 6 shows an embodiment in which multiple threshold channels are calibrated in a single measurement.
  • an imaging system 100 such as a computed tomography (CT) scanner is schematically illustrated.
  • CT computed tomography
  • the imaging system 100 includes a stationary gantry 102 and a rotating gantry 104, which is rotatably supported by the stationary gantry 102.
  • the rotating gantry 104 rotates around an examination region 106 about a longitudinal or z-axis 108.
  • a radiation source 110 such as an X-ray tube, is supported by and rotates with the rotating gantry 104 around the examination region 106 about the longitudinal or z-axis 108.
  • the radiation source 110 emits ionizing (x-ray) radiation that traverses the examination region 106 and a portion of a subject or an object located therein.
  • a detector array 112 subtends an angular arc opposite the examination region 106 relative to the radiation source 110.
  • the detector array 112 includes a one or two dimensional array of photon counting pixels, which include a direct conversion material such as cadmium telluride (CdTe), cadmium zinc telluride (CZT), silicon (Si), gallium arsenide (GaAs), and/or other direct conversion material.
  • the detector array 112 detects radiation traversing the examination region 106 and generates an electrical signal indicative of the energy thereof.
  • a pre-processor 114 processes the signal. In one instance, the processing includes amplifying the electrical signal. In a variation, the pre-processor 114 is omitted.
  • a pulse shaper 116 receives the amplified (or non-amplified) electrical signal and generates a pulse (e.g., voltage, current, etc.) having a peak height or peak amplitude that is indicative of the energy of the detected radiation.
  • a discriminator 118 includes a plurality of comparators 120, corresponding reference signal generators 122, one or more window width generators 124, and a controller 126.
  • the comparators 120 energy-discriminate the pulse, based on the peak height of the pulse and respective reference signals (energy levels) generated by the corresponding reference signal generators 122.
  • the illustrated discriminator 118 is configured to operate in at least a window based spectrum measurement mode. In this mode, a threshold scan is performed in which a measurement is taken for an energy window between two different comparators 120, for each of a plurality of different reference signal levels, as the reference signal levels are swept through.
  • the controller 126 controls the discriminator 118 such that, for a window-based spectrum measurement for a particular threshold level, a single one of the reference signal generators 122 generates a single reference signal that is used by at least two of the comparators 120, and a window width generator 124 determines the window width there between.
  • a counter 128 counts, for each energy range, a number of pulses that falls within the energy range.
  • a window based spectrum measurement determiner 130 when the discriminator 118 is in the window based spectrum measurement mode, determines a window based spectrum measurement. As described in greater detail below, in one instance the measurement is determined by a difference in the count values of the two comparators 120.
  • the window based spectral measurements are well-suited for energy component decompositions that employ an estimate of the detector pixel's response.
  • the spectral measurements are well-suited for calibrating the threshold energy levels of each of the comparators 120. For a calibration, the energy threshold level for each of the comparators 120 is checked and tuned based on measurements for the different pairs of the comparators 120.
  • a binner 132 energy-bins or assigns the counts and hence the detected radiation to an energy window, thereby energy-resolving the detected radiation.
  • a decomposer 134 decomposes the energy-resolved detected radiation.
  • the decomposer 134 may decompose the energy-resolved detected radiation into a photoelectric component, a Compton scatter component, and/or other component.
  • An example of a suitable decomposition approach is described in Alvarez et al., "Energy- selective reconstructions in x-ray computerized tomography," Phys. Med. Biol, 1976, 21 : 733-44.
  • the window based spectrum measurements and/or other information indicative of the response of the detector array 112 can be used with this approach.
  • Other approaches are also contemplated herein.
  • the decomposer 134 can be implemented with a computer processor(s) (e.g., a micro-processor, a central processing unit, etc.) executing a computer readable instruction(s) encoded or embedded on computer readable storage medium (which excludes transitory medium) such as physical memory. Additionally or alternatively, at least one of the computer readable instruction(s) is carried by a carrier wave, a signal, or other non-computer readable storage medium transitory medium.
  • a computer processor(s) e.g., a micro-processor, a central processing unit, etc.
  • a computer readable instruction(s) encoded or embedded on computer readable storage medium (which excludes transitory medium) such as physical memory.
  • at least one of the computer readable instruction(s) is carried by a carrier wave, a signal, or other non-computer readable storage medium transitory medium.
  • the pre-processor 114, the shaper 116, the discriminator 118, the counter 128, the binner 132, the window based spectrum measurement determiner 130, and the decomposer 134 are considered a detector array signal processor.
  • a reconstructor 136 reconstructs one or more of the decomposed components, producing spectral volumetric image data. Alternatively, the decomposed components are combined and reconstructed to produce non-spectral volumetric image data.
  • a subject support 138 such as a couch, supports an object or subject in the examination region 106. This includes positioning the object or subject before, during and/or after a scan of the subject or object.
  • a computing system serves as an operator console 140, and includes an output device such as a display and an input device such as a keyboard, mouse, and/or the like.
  • Software resident on the console 140 allows the operator to interact with the system 100. This may include selecting an imaging protocol, initiating scanning, invoking a comparator calibration routine, etc.
  • FIGURES 2 and 3 schematically illustrate a non-limiting example of the discriminator 118 in connection with the shaper 116 and the counter 128.
  • Such energy levels include energy levels
  • FIGURE 5 illustrates a variation with N comparators 120 for N different energy levels.
  • the N comparators 120 includes a plurality of comparators 2021, 202 2 and 202 3; each including a first input terminal 2041, 204 2 and 204 3 , a second input terminal 2061, 206 2 and 206 3 , and an output terminal 208i, 208 2 and 208 3 .
  • the reference signal generators 122 include a plurality reference signal generators 212i, 212 2 and 212 3 .
  • the first input terminals 204i, 204 2 and 204 3 are each in electrical communication with an output terminal 210 of the shaper 116.
  • the second input terminals 206i, 206 2 and 206 3 are each in electrical communication with the respective reference signal generators 212i, 212 2 and 212 3 .
  • Each of the reference signal generators 212i, 212 2 and 212 3 can generate, alternatively, one of a plurality of different reference signals, independent of the other reference signal generators 212i, 212 2 and 212 3 .
  • the reference signals similar to the pulse generated by the pulse shaper 116, are electrical signals such as voltages, currents, etc.
  • the reference signal generators 212i, 212 2 and 212 3 include digital-to-analog converters (DACs) that produce voltages in the millivolt range, which correspond to particular kV levels.
  • a kV level can be incremented and/or decremented in steps of a tenth of a kV (e.g., 0.5 kV, 1.0 kV, etc.) or larger through corresponding millivolt setting.
  • the comparators 2021, 202 2 and 202 3 respectively compare the peak height of the pulse from the shaper 116 with a corresponding reference signal generated by the reference signal generators 212i, 212 2 and 212 3 and output signals indicating which of the two signals (i.e., the pulse or the reference signal) has a larger amplitude.
  • Each of the reference signals corresponds to a different known energy level or threshold.
  • the reference signal from the reference signal generator 212 2 may correspond to 80 kV whereas the reference signal generator 212 3 may correspond to 120 kV. Other kV values are also contemplated herein.
  • the window width generator 124 includes a window width generator 214, which can generate a predetermined window width for a particular spectrum measurement and can maintain or vary the width between measurements.
  • the window widths similar to the pulse generated by the pulse shaper 116, are electrical signals such as voltages, currents, etc.
  • the window width generator 214 may include a DAC that produce voltages in the millivolt range. However, in this instance, the voltages correspond to a particular kV step.
  • a step can be as small as a tenth of a kV (e.g., 0.5 kV, 1.0 kV, etc.).
  • a first switch 216 2 resides between the second input terminal 206 2 , and the reference signal generator 212 2 .
  • the first switch 216 2 is configured to switch the second input terminal 206 2 between the reference signal generator 212 2 and the window width generator 214.
  • a second switch 218 3 resides between the second input terminal 206 3 and the window reference signal width generator 214.
  • the second switch 218 3 is configured to open and close an electrical connection between the second input terminal 206 3 and the window width generator 214.
  • the controller 126 controls the reference signal generators 212i, 212 2 and 212 3 , the window width generator 214, and the switches 216 2 and 218 3 .
  • Such control may include controlling the reference signal generators 212i, 212 2 and 212 3 to generate particular threshold energy levels for the comparators 202i, 202 2 and 202 3 , cycle through a set of predetermined reference signals for one or more of the comparators 202i, 202 2 and 202 3 , for a threshold scan, generate a particular window width, change the window width, switch in and out of the window-based spectrum measurement mode, etc.
  • the counter 128 includes a plurality of sub-counters 220i, 220 2 and 220 3 .
  • the plurality of sub-counters 220i, 220 2 and 218 3 respectively are in electrical communication with the output terminals 208i, 208 2 and 208 3 of the comparators 202 u 202 2 and 202 3 .
  • Each of the plurality of sub-counters 2201, 220 2 and 220 3 increments a count value each time a peak height of a pulse is greater than the corresponding reference signal, based on the output of the comparators 202i, 202 2 and 202 3 , which indicates whether the peak height of the pulse is greater than the corresponding reference signal.
  • the discriminator 118 operates in a non-window-based spectrum
  • Figure 3 shows the example of the discriminator 118 in the window-based spectrum measurement mode.
  • the switch 216 2 electrically connects the second input 206 2 and the window width generator 214 and disconnects the second input 206 2 from the reference signal generator 212 2
  • the switch 218 3 electrically connects the second input 206 3 and the reference signal generator 212 3 to the widow width generator 214.
  • the window width generator 214 generates a window of width "wl” and the reference signal generator 212 3 generates a reference signal with a level "nl”
  • the reference signal applied to the comparator 202 3 is "nl”
  • the reference signal applied to the comparator 202 2 is "nl + wl”.
  • the reference signal level can be simultaneously changed for both of the comparators 202 2 and 202 3 by controlling the reference signal applied to the comparator 202 3 .
  • the reference signal is changed from "nl” to "n2"' (e.g., "n2" > "nl” or "n2" ⁇ "nl")
  • the reference signal applied to the comparator 202 2 is "n2 + wl".
  • the reference signal for both the comparators 202 2 and 202 3 is subject to a same reference signal generator gain and offset. Furthermore, the window width "w" will not vary due to differences in different reference signal generator gains between two different reference signal generators. Where the window width is change from “wl” to "w2" (e.g., "w2" > “wl” or "w2" ⁇ "wl"), the reference signal applied to the comparator 202 2 is "nl + w2".
  • the sub-counter 220 2 and the sub-counter 220 3 For each reference signal applied during the threshold scan, the sub-counter 220 2 and the sub-counter 220 3 accumulates respective count values.
  • the window based spectrum measurement determiner 130 determines a number of counts within the window width by calculating a difference value between the accumulated count values of the sub- counter 220 2 and the sub-counter 220 3 (e.g., count value of the sub-counter 220 2 less the count value of the sub-counter 220 3 ).
  • the count values represent correlated measurement values since they are taken in a same measurement period.
  • FIGURE 3 is not limiting. That is, in another embodiment, there may be more than three comparators 120. Furthermore, a different pair of the comparators 120 can be used for a window based spectrum measurement. Furthermore, more than a single pair of the comparators 120 can be used for window based spectrum measurements. For a different pair and/or additional comparators 120, the comparators 120 can be electrically connected and utilized as shown in FIGURES 2 and 3.
  • FIGURE 4 illustrates a method for acquiring a window-based spectrum measurement for a decomposition of acquired data.
  • the window based spectrum measurement mode is activated.
  • a predetermined window width is set, as described herein.
  • a current reference energy threshold level is set for two comparators 120 using the same reference signal generator 122, as described herein.
  • the counter 128 counts for each of the two comparators 120, as described herein.
  • a window based spectrum measurement is determined by determining a difference in the count value for each of the comparators 120
  • acts 406-410 are repeated with the current threshold level set to the next threshold level.
  • the window-based spectrum measurements are conveyed to the decomposer 134, which decomposes the binned counts, using the window-based spectrum measurements as an estimate for the response of the detector.
  • the above may be implemented, at least in part, via one or more processors executing one or more computer readable instructions encoded or embodied on computer readable storage medium such as physical memory which causes the one or more processors to carry out the various acts and/or other functions and/or acts. Additionally or alternatively, the one or more processors can execute instructions carried by transitory medium such as a signal or carrier wave.
  • the reference signal level of a reference signal generator 122 is maintained and the window width generator 124 varies the window width. This allows for characterizing the window width.
  • FIGURE 5 shows an example in which the N comparators 120 includes comparators 202i, 202 2 , 202 3 , ... , 202 N (where N is a positive integer).
  • the comparators 202i, 202 2 , 202 3 , ... , 202 N respectively have N first inputs 204, including first inputs 204i, 204 2 , 204 3 , ... , 204 N , N second inputs 206, including second inputs 206i, 206 2 , 206 3 , ... , 206 N , and N outputs 208, including outputs 208i, 208 2 , 208 3 , ... , 208 N .
  • the window width generators 124 include window width generators 214, including window width generators 214 ! , 214 2 , 214 3 , ... , 214 N .
  • the reference signal generators 122 include N reference signal generators 212, including reference signal generators 212i, 212 2 , 212 3 , ... , 212 N .
  • First switches 216 including first switches 216i, 216 2 , 216 3 , ... , 216 N connect the N second inputs 206i, 206 2 , 206 3 , 206 N to either the reference signal generators 212i, 212 2 , 212 3 , 212 N or the window width generators 214i, 214 2 , 214 3 , ... , 214 N -i.
  • Seconds switches, including second switches 218i, 218 2 , 218 3 , ... , 218 N are between the window width generators 214i, 214 2 , 214 3 , 214 N- i and the N reference signal generators 212i, 212 2 , 212 3 , ... , 212 N .
  • FIGURE 5 for sake of clarity, a single window width generator 214 is shown located between each of the comparators 202, and the window width generators 214 are in series. With the configuration, a window based spectrum measurement for
  • comparators 202i and 202 3 can use the window width generator 214i, 214 2 , or both 214i and 214 2 to set the window width.
  • window based spectrum measurements can be used by the decomposer 134 and/or to calibrate the threshold level of each of the reference signals generators 122 for each of the comparators 120.
  • at least one of the comparators 120 is not configured for a window based spectrum measurements, similar to the comparator 202i of FIGURE 3.
  • all N threshold channels are calibrated in a single measurement (rather than sequential measurements).
  • two of the comparators 120 with logic, are used with N of the window width generators 124.
  • the reference signal for a first of the two comparators 120 is provided by one of the reference generators 122, while the reference signal for a second of the two comparators 120 is a summation of this reference signal and a window width provided by the N window width generators 124.
  • an event is counted only if the first of the two comparators 120 trips and the second of the comparator 120 does not trip.
  • a switching network can be used to allow for window-based spectrum measurement for calibration purposes (involving the two comparators and the logic) or normal operation (involving only the first of the two comparators without the logic, i.e. a count is recorded as soon as the first of the two comparators trips).
  • the window widths provided by the N window width generators 124 are similar to each other. This may be achieved once by characterizing the window width as a function of the DAC values controlling the window width and storing those DAC values which lead to very similar window-widths values.
  • the DAC is implemented with a larger number of bits (e.g. 6 bit), so that the least significant bit (LSB) corresponds to, e.g., 1/64 of the intended window width (a 0 width can be excluded).
  • FIGURE 6 shows an embodiment in which multiple (e.g., at least two, all, etc.) threshold channels are calibrated in a single measurement, rather than sequential
  • comparators 202 is replaced with two comparators.
  • 202i is replaced with 202n and 202i 2
  • 202 2 is replaced with 202 2 i and 202 22
  • ... , 202 N is replaced with 202 N i and 202 N2 .
  • a first set of input channels of the comparators 202i 2 and 202 22 , ... , 202 N2 is electrically connected directly to the output of the shaper 116.
  • a first set of switches 702i, 702 2 , ... , 702 N respectively electrically connect and disconnects the output of the shaper 116 with a set of first input channels of the comparators 202 n and 202 21 , ... , 202 N i.
  • a second set of input channels of the comparators 202i 2 and 202 22 , ... , 202 N2 is respectively electrically connected to the reference signal generators 212i, 212 2 , ... , 212 N .
  • a second set of input channels of the comparators 202n and 202 21 , ... , 202 N i is respectively electrically connected to the window width generators 214i, 214 2 , ... , 214 N .
  • a second set of switches 704i, 704 2 , ... , 704 N respectively electrically connect and disconnects the window width generators 214i, 214 2 , ... , 214 N with the reference signal generators 212i, 212 2 , ... , 212 N .
  • Logic 700 includes a set of sub-logic 706i, 706 2 , ... , 706 N .
  • a third set of switches 708i, 708 2 , ... , 708 N electrically connects and disconnects the outputs of the comparators 202ii and 202 21 , ... , 202 m with the sub-logic 706i, 706 2 , ... , 706 N .
  • the outputs of the comparators 202i 2 and 202 22 , ... , 202 N2 are electrically connected to the sub-logic 706i, 706 2 , ... , 706 N .
  • the first set of switches 702i, 702 2 , ... , 702 N is closed and electrically connects the output of the shaper 116 and the comparators 202n and 202 21 , ... , 202 N i.
  • the second set of switches 704i, 704 2 , ... , 704 N is closed and electrically connects the window width generators 214i, 214 2 , ... , 214 N and the reference signal generators 212i, 212 2 , ... , 212 N .
  • the third set of switches 708i, 708 2 , ... , 708 N is closed and electrically connects the output of the comparators 202n, 202 21 , ...
  • the logic 700 outputs a pulse only when a pulse has a height , which is not larger than the value of the reference signal generators 212i, 212 2 , 212 N plus the value of the window width generators 214i, 214 2 , ... , 214 N and larger than the value of the reference signal generators 212i, 212 2 , ... , 212 N , in other words a height, which is between both these two levels.
  • the first set of switches 702i, 702 2 , ... , 702 N is open and electrically disconnects the output of the shaper 116 with the comparators 202n and 202 2 i, ... , 202 N i.
  • the second set of switches 704i, 704 2 , ... , 704 N is open and electrically disconnects the window width generators 214i, 214 2 , ... , 214 N and the reference signal generators 212i, 212 2 , ... , 212 N .
  • the third set of switches 708i, 708 2 , ... , 708 N is open and electrically disconnects the output of the comparators 202n, 202 2 i, ...
  • the first set of comparators 202n and 202 2 i, ... , 202 N i is disabled, and the logic 700 outputs the outputs of the comparators 202i 2 and 202 22 , ... , 202 N2 .
  • the window widths provided by the N window width generators 124 are similar to each other. This may be achieved once by characterizing the window width as a function of the DAC values controlling the window width and storing those DAC values which lead to very similar window-widths values.
  • the DAC is implemented with a larger number of bits (e.g. 6 bit), so that the least significant bit (LSB) corresponds to, e.g., 1/64 of the intended window width (a 0 width can be excluded).
  • the window-based spectrum measurement may be taken during an air scan, with the purpose of determining the detector response for each pixel at a given X-ray energy.
  • a plurality of K-edge filters e.g. Pb for 89keV, Gd for 60keV
  • the frequency the measurement is taken depends, e.g., on the stability of the detector response.
  • the spectrum measurement can also be used to do tube and detector
  • K-edge filters are not used.
  • Radio-active sources that irradiate at a fixed energy may or may not be used.

Landscapes

  • Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Molecular Biology (AREA)
  • Measurement Of Radiation (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)

Abstract

A discriminator (118) includes a set of comparators (120, 2021, 2022, 2023,…,202N), a window width generator (124, 214, 2141, …, 214N), and a set of reference signal genrators (122, 2121, 2122, 2123, …, 212N). In response to the discriminator being in a window based spectrum measurement mode, a first reference signal generator for a first comparator generates a reference signal that is supplied to the first comparator and that is added with the window width with a result of the addition supplied to the second comparator. The first comparator compares a peak height of a pulse indicative of an energy of detected radiation with the supplied reference signal and produces a first output indicating which of the peak height or the reference signal is greater. The second comparator compares the peak height with the supplied result of the addition and produces a second output indicating which of the peak height or the result of the addition is greater.

Description

WINDOW-BASED SPECTRUM MEASUREMENT IN A SPECTRAL CT DETECTOR
FIELD OF THE INVENTION
The following generally relates to a photon counting detector and is described with particular application to computed tomography (CT); however, the following is also amenable to other imaging modalities.
BACKGROUND OF THE INVENTION
A computed tomography (CT) scanner generally includes a rotating gantry rotatably mounted to a stationary gantry. The rotating gantry supports an X-ray tube and is configured to rotate around an examination region about a longitudinal or Z-axis. A detector array is located opposite the X-ray tube, across the examination region. The X-ray tube is configured to emit radiation that traverses the examination region (and a portion of an object or a subject therein) and impinges upon the detector array. The detector array includes a one or two dimensional array of detector pixels that detect the radiation and produce signals indicative thereof. Each pixel conveys a corresponding signal for further processing. A reconstructor reconstructs the signals, producing volumetric image.
For spectral CT, the detector pixels can include a direct conversion material disposed between a cathode and an anode with a voltage applied across the cathode and anode. Photons strike the cathode, transferring energy to electrons in the direct conversion material, which creates electron/hole pairs, with the electrons drifting towards the anode. The anode produces the electrical signals output by the detector array. A pulse shaper processes the signals and produces pulses having peak heights indicative of the energy of the detected radiation. A discriminator compares, with comparators, the heights with a set of energy thresholds. For each threshold, a counter counts a number of times a pulse height crosses the threshold. A binner bins the counts in energy-ranges. A decomposer decomposes the binned data, e.g., into spectral components. The reconstructor reconstructs the spectral components.
The forward-model-based evaluation technique of measured photon-counting data, e.g., using the Alvarez-Macovsky decomposition, requires an accurate estimate of the detector pixels' detector response, i.e., for different single excitation energies, the spectrum of absorbed energies. Using a photon-counting readout channel for a detector pixel, the detector response can be obtained by differentiating a threshold scan obtained with one of the available comparators. Unfortunately, such a measurement is highly noisy since the differentiation amplifies the inherent noise within the threshold scan data. For example, discrete differentiation implies subtraction of two statistically independent noisy Poisson random variables, so that the resulting variance equals the sum of the individual variances.
By using two different comparators, a window based spectrum measurement can be implemented. By measuring the (Poisson distributed) counts within the energy window defined by the two comparators, the resulting noise is considerably reduced, at least because the number of counts within the window is much smaller than the number of counts above one of the thresholds. However, gain mismatches between the two comparators results in window widths that vary, or will not be constant, across the range of all threshold levels. As a consequence, the measurements require significant correction, resulting in a complex measurement procedure.
Aspects described herein addresses the above-referenced problems and others.
SUMMARY OF THE INVENTION
In one aspect, a detector array signal processor of an imaging system includes a discriminator. The discriminator includes a set of comparators, a window width generator that generates a window width for a window based spectrum measurement, and a set of reference signal generators, each corresponding to a different one of the comparators, which generate different reference signals. In response to the discriminator being in a window based spectrum measurement mode, a first reference signal generator for a first comparator generates a reference signal that is supplied to the first comparator and that is added with the window width with a result of the addition supplied to the second comparator. The first comparator compares a peak height of a pulse indicative of an energy of detected radiation with the supplied reference signal and produces a first output indicating which of the peak height or the reference signal is greater. The second comparator compares the peak height with the supplied result of the addition and produces a second output indicating which of the peak height or the result of the addition is greater.
In another aspect, a method includes receiving, sequentially, a plurality of pulses, each having a peak height indicative of an energy of different detected radiation, a window width for a window based spectrum measurement, and a set of reference signals for a first comparator. The method further includes providing the pulse and, sequentially, each of the reference signals of the set to the first comparator and the pulse and, sequentially, each of the reference signals added to the window width to a second comparator. The method further includes counting a first number of times a first output of the first comparator exceeds the reference signals and a second number of times a second output of the second comparator exceeds the reference signals added to the window width. The method further includes determining a window based spectrum measurement for each of the different reference signals by determining a difference between the first number and the second number for the corresponding reference signals.
In another aspect, a method includes receiving, sequentially, a plurality of pulses, each having a peak height indicative of an energy of different detected radiation, a window width for a window based spectrum measurement, and a set of reference signals for a first comparator. The method further includes providing the pulse and, sequentially, each of the reference signals of the set to the first comparator, and the pulse and, sequentially, each of the reference signals added to the window width to a second comparator. The method further includes counting a first number of times a first output of the first comparator exceeds the reference signals and counting a second number of times a second output of the second comparator exceeds the reference signals added to the window width. The method further includes calibrating an energy threshold of at least one of the first or the second comparators based on the window based spectrum measurements.
BRIEF DESCRIPTION OF THE DRAWINGS
The invention may take form in various components and arrangements of components, and in various steps and arrangements of steps. The drawings are only for purposes of illustrating the preferred embodiments and are not to be construed as limiting the invention.
FIGURE 1 schematically illustrates an example imaging system with a discriminator configured to operate in a window based spectrum measurement mode.
FIGURE 2 schematically illustrates an example of the discriminator in a non- window based spectrum measurement mode.
FIGURE 3 schematically illustrates an example of the discriminator in the window based spectrum measurement mode.
FIGURE 4 illustrates an example method for taking window based spectrum measurements. FIGURE 5 schematically illustrates an example of the discriminator with N comparators.
FIGURE 6 shows an embodiment in which multiple threshold channels are calibrated in a single measurement.
DETAILED DESCRIPTION OF EMBODIMENTS
Initially referring to FIGURE 1, an imaging system 100 such as a computed tomography (CT) scanner is schematically illustrated.
The imaging system 100 includes a stationary gantry 102 and a rotating gantry 104, which is rotatably supported by the stationary gantry 102. The rotating gantry 104 rotates around an examination region 106 about a longitudinal or z-axis 108.
A radiation source 110, such as an X-ray tube, is supported by and rotates with the rotating gantry 104 around the examination region 106 about the longitudinal or z-axis 108. The radiation source 110 emits ionizing (x-ray) radiation that traverses the examination region 106 and a portion of a subject or an object located therein.
A detector array 112 subtends an angular arc opposite the examination region 106 relative to the radiation source 110. The detector array 112 includes a one or two dimensional array of photon counting pixels, which include a direct conversion material such as cadmium telluride (CdTe), cadmium zinc telluride (CZT), silicon (Si), gallium arsenide (GaAs), and/or other direct conversion material. The detector array 112 detects radiation traversing the examination region 106 and generates an electrical signal indicative of the energy thereof.
A pre-processor 114 processes the signal. In one instance, the processing includes amplifying the electrical signal. In a variation, the pre-processor 114 is omitted. A pulse shaper 116 receives the amplified (or non-amplified) electrical signal and generates a pulse (e.g., voltage, current, etc.) having a peak height or peak amplitude that is indicative of the energy of the detected radiation.
A discriminator 118 includes a plurality of comparators 120, corresponding reference signal generators 122, one or more window width generators 124, and a controller 126. The comparators 120 energy-discriminate the pulse, based on the peak height of the pulse and respective reference signals (energy levels) generated by the corresponding reference signal generators 122. The illustrated discriminator 118 is configured to operate in at least a window based spectrum measurement mode. In this mode, a threshold scan is performed in which a measurement is taken for an energy window between two different comparators 120, for each of a plurality of different reference signal levels, as the reference signal levels are swept through. As described in greater detail below, the controller 126 controls the discriminator 118 such that, for a window-based spectrum measurement for a particular threshold level, a single one of the reference signal generators 122 generates a single reference signal that is used by at least two of the comparators 120, and a window width generator 124 determines the window width there between.
A counter 128 counts, for each energy range, a number of pulses that falls within the energy range.
A window based spectrum measurement determiner 130, when the discriminator 118 is in the window based spectrum measurement mode, determines a window based spectrum measurement. As described in greater detail below, in one instance the measurement is determined by a difference in the count values of the two comparators 120. By using a single reference signal generator 122 and a window width generator 124, instead of two different reference signal generators 122 for the two comparators 120, performance differences offset and gain mismatches between reference signal generators 122 are mitigated, and the window width is well-defined. As a consequence, the window based spectral measurements are well-suited for energy component decompositions that employ an estimate of the detector pixel's response. Furthermore, the spectral measurements are well-suited for calibrating the threshold energy levels of each of the comparators 120. For a calibration, the energy threshold level for each of the comparators 120 is checked and tuned based on measurements for the different pairs of the comparators 120.
A binner 132 energy-bins or assigns the counts and hence the detected radiation to an energy window, thereby energy-resolving the detected radiation.
A decomposer 134 decomposes the energy-resolved detected radiation. For example, the decomposer 134 may decompose the energy-resolved detected radiation into a photoelectric component, a Compton scatter component, and/or other component. An example of a suitable decomposition approach is described in Alvarez et al., "Energy- selective reconstructions in x-ray computerized tomography," Phys. Med. Biol, 1976, 21 : 733-44. The window based spectrum measurements and/or other information indicative of the response of the detector array 112 can be used with this approach. Other approaches are also contemplated herein.
It is to be appreciated that the decomposer 134 can be implemented with a computer processor(s) (e.g., a micro-processor, a central processing unit, etc.) executing a computer readable instruction(s) encoded or embedded on computer readable storage medium (which excludes transitory medium) such as physical memory. Additionally or alternatively, at least one of the computer readable instruction(s) is carried by a carrier wave, a signal, or other non-computer readable storage medium transitory medium.
It is to be appreciated that in some embodiments the pre-processor 114, the shaper 116, the discriminator 118, the counter 128, the binner 132, the window based spectrum measurement determiner 130, and the decomposer 134 are considered a detector array signal processor.
A reconstructor 136 reconstructs one or more of the decomposed components, producing spectral volumetric image data. Alternatively, the decomposed components are combined and reconstructed to produce non-spectral volumetric image data. A subject support 138, such as a couch, supports an object or subject in the examination region 106. This includes positioning the object or subject before, during and/or after a scan of the subject or object.
A computing system serves as an operator console 140, and includes an output device such as a display and an input device such as a keyboard, mouse, and/or the like. Software resident on the console 140 allows the operator to interact with the system 100. This may include selecting an imaging protocol, initiating scanning, invoking a comparator calibration routine, etc.
FIGURES 2 and 3 schematically illustrate a non-limiting example of the discriminator 118 in connection with the shaper 116 and the counter 128.
For sake of brevity and clarity, this example is discussed in connection with three comparators 120. Such energy levels, in one instance, include energy levels
corresponding to at least two different energy levels (e.g., low and high) such as the photoelectric effect and Compton scatter, the noise floor, etc. However, it is to be understood that in other embodiments, other energy levels, including more than three energy levels are contemplated herein. For example, FIGURE 5 illustrates a variation with N comparators 120 for N different energy levels.
The N comparators 120 includes a plurality of comparators 2021, 2022 and 2023; each including a first input terminal 2041, 2042 and 2043, a second input terminal 2061, 2062 and 2063, and an output terminal 208i, 2082 and 2083. The reference signal generators 122 include a plurality reference signal generators 212i, 2122 and 2123. The first input terminals 204i, 2042 and 2043 are each in electrical communication with an output terminal 210 of the shaper 116. The second input terminals 206i, 2062 and 2063 are each in electrical communication with the respective reference signal generators 212i, 2122 and 2123. Each of the reference signal generators 212i, 2122 and 2123 can generate, alternatively, one of a plurality of different reference signals, independent of the other reference signal generators 212i, 2122 and 2123. The reference signals, similar to the pulse generated by the pulse shaper 116, are electrical signals such as voltages, currents, etc. In one instance, the reference signal generators 212i, 2122 and 2123 include digital-to-analog converters (DACs) that produce voltages in the millivolt range, which correspond to particular kV levels. A kV level can be incremented and/or decremented in steps of a tenth of a kV (e.g., 0.5 kV, 1.0 kV, etc.) or larger through corresponding millivolt setting.
The comparators 2021, 2022 and 2023 respectively compare the peak height of the pulse from the shaper 116 with a corresponding reference signal generated by the reference signal generators 212i, 2122 and 2123 and output signals indicating which of the two signals (i.e., the pulse or the reference signal) has a larger amplitude. Each of the reference signals corresponds to a different known energy level or threshold. By way of non- limiting example, the reference signal from the reference signal generator 2122 may correspond to 80 kV whereas the reference signal generator 2123 may correspond to 120 kV. Other kV values are also contemplated herein.
The window width generator 124 includes a window width generator 214, which can generate a predetermined window width for a particular spectrum measurement and can maintain or vary the width between measurements. The window widths, similar to the pulse generated by the pulse shaper 116, are electrical signals such as voltages, currents, etc. Similar to the reference signal generator 212i, 2122 and 2123, the window width generator 214 may include a DAC that produce voltages in the millivolt range. However, in this instance, the voltages correspond to a particular kV step. A step can be as small as a tenth of a kV (e.g., 0.5 kV, 1.0 kV, etc.).
A first switch 2162 resides between the second input terminal 2062, and the reference signal generator 2122. The first switch 2162 is configured to switch the second input terminal 2062 between the reference signal generator 2122 and the window width generator 214. A second switch 2183 resides between the second input terminal 2063 and the window reference signal width generator 214. The second switch 2183 is configured to open and close an electrical connection between the second input terminal 2063 and the window width generator 214.
The controller 126 controls the reference signal generators 212i, 2122 and 2123, the window width generator 214, and the switches 2162 and 2183. Such control may include controlling the reference signal generators 212i, 2122 and 2123 to generate particular threshold energy levels for the comparators 202i, 2022 and 2023, cycle through a set of predetermined reference signals for one or more of the comparators 202i, 2022 and 2023, for a threshold scan, generate a particular window width, change the window width, switch in and out of the window-based spectrum measurement mode, etc.
The counter 128 includes a plurality of sub-counters 220i, 2202 and 2203. The plurality of sub-counters 220i, 2202 and 2183 respectively are in electrical communication with the output terminals 208i, 2082 and 2083 of the comparators 202u 2022 and 2023. Each of the plurality of sub-counters 2201, 2202 and 2203 increments a count value each time a peak height of a pulse is greater than the corresponding reference signal, based on the output of the comparators 202i, 2022 and 2023, which indicates whether the peak height of the pulse is greater than the corresponding reference signal.
With the switches 2162 and 2183 in the position shown in Figure 2 (in which the switch 2162 electrically connects the second input 2062 and to the reference signal generator 2122 and disconnects the second input 2062 from the widow width generator 214, and the switch 2183 electrically disconnects the second input 2063 from the widow width generator 214), the discriminator 118 operates in a non-window-based spectrum
measurement mode.
Figure 3 shows the example of the discriminator 118 in the window-based spectrum measurement mode. For this, the switch 2162 electrically connects the second input 2062 and the window width generator 214 and disconnects the second input 2062 from the reference signal generator 2122, and the switch 2183 electrically connects the second input 2063 and the reference signal generator 2123 to the widow width generator 214.
Where the window width generator 214 generates a window of width "wl" and the reference signal generator 2123 generates a reference signal with a level "nl", the reference signal applied to the comparator 2023 is "nl" and the reference signal applied to the comparator 2022 is "nl + wl". The reference signal level can be simultaneously changed for both of the comparators 2022 and 2023 by controlling the reference signal applied to the comparator 2023. Where the reference signal is changed from "nl" to "n2"' (e.g., "n2" > "nl" or "n2" < "nl"), the reference signal applied to the comparator 2022 is "n2 + wl".
Since the same reference signal generator signal generator 2123 generates the reference signal for both the comparators 2022 and 2023, the reference signal for both the comparators 2022 and 2023 is subject to a same reference signal generator gain and offset. Furthermore, the window width "w" will not vary due to differences in different reference signal generator gains between two different reference signal generators. Where the window width is change from "wl" to "w2" (e.g., "w2" > "wl" or "w2" < "wl"), the reference signal applied to the comparator 2022 is "nl + w2".
For each reference signal applied during the threshold scan, the sub-counter 2202 and the sub-counter 2203 accumulates respective count values. The window based spectrum measurement determiner 130 determines a number of counts within the window width by calculating a difference value between the accumulated count values of the sub- counter 2202 and the sub-counter 2203 (e.g., count value of the sub-counter 2202 less the count value of the sub-counter 2203). The count values represent correlated measurement values since they are taken in a same measurement period.
Again, the example of FIGURE 3 is not limiting. That is, in another embodiment, there may be more than three comparators 120. Furthermore, a different pair of the comparators 120 can be used for a window based spectrum measurement. Furthermore, more than a single pair of the comparators 120 can be used for window based spectrum measurements. For a different pair and/or additional comparators 120, the comparators 120 can be electrically connected and utilized as shown in FIGURES 2 and 3.
FIGURE 4 illustrates a method for acquiring a window-based spectrum measurement for a decomposition of acquired data.
It is to be appreciated that the ordering of the acts in the methods described herein is not limiting. As such, other orderings are contemplated herein. In addition, one or more acts may be omitted and/or one or more additional acts may be included.
At 402, the window based spectrum measurement mode is activated.
At 404, a predetermined window width is set, as described herein.
At 406, a current reference energy threshold level is set for two comparators 120 using the same reference signal generator 122, as described herein.
At 408, the counter 128 counts for each of the two comparators 120, as described herein.
At 410, a window based spectrum measurement is determined by determining a difference in the count value for each of the comparators 120
At 412, it is determined whether there is a next reference signal level.
In response to there being another reference signal level, acts 406-410 are repeated with the current threshold level set to the next threshold level.
In response to there not being another reference signal level, at 414, the window-based spectrum measurements are conveyed to the decomposer 134, which decomposes the binned counts, using the window-based spectrum measurements as an estimate for the response of the detector.
The above may be implemented, at least in part, via one or more processors executing one or more computer readable instructions encoded or embodied on computer readable storage medium such as physical memory which causes the one or more processors to carry out the various acts and/or other functions and/or acts. Additionally or alternatively, the one or more processors can execute instructions carried by transitory medium such as a signal or carrier wave.
In a variation, the reference signal level of a reference signal generator 122 is maintained and the window width generator 124 varies the window width. This allows for characterizing the window width.
FIGURE 5 shows an example in which the N comparators 120 includes comparators 202i, 2022, 2023, ... , 202N (where N is a positive integer). The comparators 202i, 2022, 2023, ... , 202N respectively have N first inputs 204, including first inputs 204i, 2042, 2043, ... , 204N, N second inputs 206, including second inputs 206i, 2062, 2063, ... , 206N, and N outputs 208, including outputs 208i, 2082, 2083, ... , 208N. The window width generators 124 include window width generators 214, including window width generators 214!, 2142, 2143, ... , 214N.
The reference signal generators 122 include N reference signal generators 212, including reference signal generators 212i, 2122, 2123, ... , 212N. First switches 216, including first switches 216i, 2162, 2163, ... , 216N connect the N second inputs 206i, 2062, 2063, 206N to either the reference signal generators 212i, 2122, 2123, 212N or the window width generators 214i, 2142, 2143, ... , 214N-i. Seconds switches, including second switches 218i, 2182, 2183, ... , 218N are between the window width generators 214i, 2142, 2143, 214N-i and the N reference signal generators 212i, 2122, 2123, ... , 212N.
In FIGURE 5, for sake of clarity, a single window width generator 214 is shown located between each of the comparators 202, and the window width generators 214 are in series. With the configuration, a window based spectrum measurement for
comparators 202i and 2023 can use the window width generator 214i, 2142, or both 214i and 2142 to set the window width.
In a variation of FIGURE 5, a single and different window width generator 124 is utilized for each pair of comparators 120. In either instance, window based spectrum measurements can be used by the decomposer 134 and/or to calibrate the threshold level of each of the reference signals generators 122 for each of the comparators 120. In another variation of FIGURE 5, at least one of the comparators 120 is not configured for a window based spectrum measurements, similar to the comparator 202i of FIGURE 3.
In another embodiment, all N threshold channels are calibrated in a single measurement (rather than sequential measurements). For example, in one instance, for each of the N thresholds, two of the comparators 120, with logic, are used with N of the window width generators 124. The reference signal for a first of the two comparators 120 is provided by one of the reference generators 122, while the reference signal for a second of the two comparators 120 is a summation of this reference signal and a window width provided by the N window width generators 124.
With logic, an event is counted only if the first of the two comparators 120 trips and the second of the comparator 120 does not trip. With this configuration, only the counts within the window defined by the window width generator 124 are recorded. In addition, a switching network can be used to allow for window-based spectrum measurement for calibration purposes (involving the two comparators and the logic) or normal operation (involving only the first of the two comparators without the logic, i.e. a count is recorded as soon as the first of the two comparators trips).
In order to get comparable spectra for all N channels, the window widths provided by the N window width generators 124 are similar to each other. This may be achieved once by characterizing the window width as a function of the DAC values controlling the window width and storing those DAC values which lead to very similar window-widths values. In order get sufficiently similar window widths, the DAC is implemented with a larger number of bits (e.g. 6 bit), so that the least significant bit (LSB) corresponds to, e.g., 1/64 of the intended window width (a 0 width can be excluded).
FIGURE 6 shows an embodiment in which multiple (e.g., at least two, all, etc.) threshold channels are calibrated in a single measurement, rather than sequential
measurements. In this example of the comparators 202 is replaced with two comparators. For instance, 202i is replaced with 202n and 202i2, 2022 is replaced with 2022i and 20222, ... , 202N is replaced with 202Ni and 202N2. A first set of input channels of the comparators 202i2 and 20222, ... , 202N2 is electrically connected directly to the output of the shaper 116. A first set of switches 702i, 7022, ... , 702N respectively electrically connect and disconnects the output of the shaper 116 with a set of first input channels of the comparators 202 n and 20221, ... , 202Ni. A second set of input channels of the comparators 202i2 and 20222, ... , 202N2 is respectively electrically connected to the reference signal generators 212i, 2122, ... , 212N. A second set of input channels of the comparators 202n and 20221, ... , 202Ni is respectively electrically connected to the window width generators 214i, 2142, ... , 214N. A second set of switches 704i, 7042, ... , 704N respectively electrically connect and disconnects the window width generators 214i, 2142, ... , 214N with the reference signal generators 212i, 2122, ... , 212N. Logic 700 includes a set of sub-logic 706i, 7062, ... , 706N. A third set of switches 708i, 7082, ... , 708N electrically connects and disconnects the outputs of the comparators 202ii and 20221, ... , 202m with the sub-logic 706i, 7062, ... , 706N. The outputs of the comparators 202i2 and 20222, ... , 202N2 are electrically connected to the sub-logic 706i, 7062, ... , 706N.
For calibration, the first set of switches 702i, 7022, ... , 702N is closed and electrically connects the output of the shaper 116 and the comparators 202n and 20221, ... , 202Ni. The second set of switches 704i, 7042, ... , 704N is closed and electrically connects the window width generators 214i, 2142, ... , 214N and the reference signal generators 212i, 2122, ... , 212N. The third set of switches 708i, 7082, ... , 708N is closed and electrically connects the output of the comparators 202n, 20221, ... , 202Ni and the sub-logic 706i, 7062, ... , 706N. In this configuration, the logic 700 outputs a pulse only when a pulse has a height , which is not larger than the value of the reference signal generators 212i, 2122, 212N plus the value of the window width generators 214i, 2142, ... , 214N and larger than the value of the reference signal generators 212i, 2122, ... , 212N, in other words a height, which is between both these two levels.
For non-calibration (or normal) operation, the first set of switches 702i, 7022, ... , 702N is open and electrically disconnects the output of the shaper 116 with the comparators 202n and 2022i, ... , 202Ni. The second set of switches 704i, 7042, ... , 704N is open and electrically disconnects the window width generators 214i, 2142, ... , 214N and the reference signal generators 212i, 2122, ... , 212N. The third set of switches 708i, 7082, ... , 708N is open and electrically disconnects the output of the comparators 202n, 2022i, ... , 202Ni and the sub-logic 706i, 7062, ..., 706N. In this configuration, the first set of comparators 202n and 2022i, ... , 202Ni is disabled, and the logic 700 outputs the outputs of the comparators 202i2 and 20222, ... , 202N2.
In order to get comparable spectra for all N channels, the window widths provided by the N window width generators 124 are similar to each other. This may be achieved once by characterizing the window width as a function of the DAC values controlling the window width and storing those DAC values which lead to very similar window-widths values. In order get sufficiently similar window widths, the DAC is implemented with a larger number of bits (e.g. 6 bit), so that the least significant bit (LSB) corresponds to, e.g., 1/64 of the intended window width (a 0 width can be excluded).
The window-based spectrum measurement may be taken during an air scan, with the purpose of determining the detector response for each pixel at a given X-ray energy. For this, a plurality of K-edge filters (e.g. Pb for 89keV, Gd for 60keV) can be used. The frequency the measurement is taken depends, e.g., on the stability of the detector response. In addition, the spectrum measurement can also be used to do tube and detector
characterization during a regular maintenance session. In this instance, K-edge filters are not used. Radio-active sources that irradiate at a fixed energy may or may not be used.
The invention has been described with reference to the preferred embodiments. Modifications and alterations may occur to others upon reading and understanding the preceding detailed description. It is intended that the invention be constructed as including all such modifications and alterations insofar as they come within the scope of the appended claims or the equivalents thereof.

Claims

1. A detector array signal processor of an imaging system (100), comprising:
a discriminator (1 18), including:
a set of comparators (120, 202u 2022, 2023, . . . , 202N);
a window width generator (124, 214, 214i, . . . , 214N) that is configured to generate a window width for a window based spectrum measurement; and
a set of reference signal generators (122, 212i, 2122, 2123, . . . , 212N), each corresponding to a different one of the comparators, which are configured to generate different reference signals;
wherein, in response to the discriminator being in a window based spectrum measurement mode, a first reference signal generator for a first comparator is configured to generate a first reference signal that is supplied to the first comparator and that is added with the window width to create a second reference signal, which is to be supplied to the second comparator,
wherein the first comparator is configured to compare a peak height of a pulse indicative of an energy of detected radiation with the first reference signal and to produce a first output indicating which of the peak height or the first reference signal is greater; and wherein the second comparator is configured to compare the peak height with the second reference signal and to produce a second output indicating which of the peak height or the second reference signal is greater.
2. The detector array signal processor of claim 1, further comprising:
a shaper (1 16) that is configured to process a signal produced by a direct conversion detector pixel in response to the direct conversion detector pixel detecting radiation emitted by the imaging system and to generate the pulse.
3. The detector array signal processor of claim 2, further comprising:
a pre-processor (1 14) that is configured to amplify the signal produced by the direct conversion detector pixel, wherein the shaper is configured to process the amplified signal.
4. The detector array signal processor of any of claims 1 to 3, further comprising:
a counter (128, 220u 2202, 2203, . . . , 220N) that is configured to increment a first count value in response to the peak height exceeding the first reference signal and a second count value in response to the peak height exceeding the second reference signal.
5. The detector array signal processor of claim 4, further comprising:
a controller (126) that is configured to invoke the first reference signal generator to sweep through a set of different reference signals, each sequentially supplied to the first comparator and each sequentially added with the window width with the addition sequentially supplied to the second comparator,
wherein the counter is configured to increment the first count value respectively for each of the different reference signals of the set in response to the peak height respectively exceeding each of the different reference signals, and
wherein the counter is configured to increment the second count value respectively for each of the different reference signals of the set in response to the peak height respectively exceeding each of the different reference signals added with the window width .
6. The detector array signal processor of claim 5, further comprising:
a window based spectrum measurement determiner (130) that is configured to determine window based spectrum measurements by calculating differences between count values for the second comparator and count values for the first comparator.
7. The detector array signal processor of claim 6, wherein, in response to the discriminator not being in the window based spectrum measurement mode, the first reference signal generator is configured to supply a third reference signal to the first comparator, which is configured to generate a third output, and a second reference signal generator is configured to generate a fourth different reference signal and to supply the fourth difference reference signal to the second comparator, which is configured to generate a fourth output, and the counter is configured to count a number of times peak heights of a plurality of different input pulses exceeds the third reference signal and a number of times the peak heights of the plurality of different input pulses exceeds the third reference signal.
8. The detector array signal processor of claim 7, further comprising:
a binner (132) that is configured to bin the counts for the third reference signal and the counts for the fourth reference signal into corresponding energy ranges.
9. The detector array signal processor of claim 8, further comprising:
a decomposer (134) that is configured to decompose the binned counts into different energy components, using the window based spectrum measurements.
10. The detector array signal processor of claim 9, wherein the different energy components includes a first energy component corresponding to a first energy and a second energy component corresponding to a second energy, wherein the first energy is greater than the second energy.
11. The detector array signal processor of claim 9, further comprising:
a reconstructor (136) that is configured to reconstruct the first energy component and to generate a first image corresponding to the first energy component and that is configured to reconstruct the second energy component and to generate a second image corresponding to the second energy component.
12. The detector array signal processor of any of claims 5 to 11, wherein the controller is configured to maintain the first reference signal and to invoke the window based spectrum measurement determiner to change a value of the window width.
13. The detector array signal processor of any of claims 1 to 5, wherein the controller is configured to calibrate an energy threshold of the first comparator based on the window based spectrum measurements.
14. A method, comprising:
receiving, sequentially, a plurality of pulses, each having a peak height indicative of an energy of different detected radiation;
receiving a window width for a window based spectrum measurement;
receiving a set of reference signals for a first comparator;
providing the pulse and, sequentially, each of the reference signals of the set to the first comparator;
providing the pulse and, sequentially, each of the reference signals added to the window width to a second comparator;
counting a first number of times a first output of the first comparator exceeds the reference signals;
counting a second number of times a second output of the second comparator exceeds the reference signals added to the window width; and
determining a window based spectrum measurement for each of the different reference signals by determining a difference between the first number and the second number for the corresponding reference signals.
15. The method of claim 14, further comprising:
employing the window based spectrum measurements in a decomposition of photon-counting data that uses an estimate of a response of a photon counting detector.
16. The method of any of claims 14 to 15, wherein the set of reference signals correspond to kV values and increase in increments on the order of tenths of kVs.
17. The method of any of claims 15 to 16, further comprising:
changing a value of the window width based on a step, where the step corresponds to a predetermined kV value and increase in increments on the order of tenths of
18. The method of any of claims 15 to 17, further comprising:
determining window based spectrum measurements for all of the comparators.
19. The method of claim 18, further comprising:
calibrating an energy threshold of a comparator with the corresponding window based spectrum measurement.
20. A method, comprising:
receiving, sequentially, a plurality of pulses, each having a peak height indicative of an energy of different detected radiation;
receiving a window width for a window based spectrum measurement;
receiving a set of reference signals for a first comparator;
providing the pulse and, sequentially, each of the reference signals of the set to the first comparator;
providing the pulse and, sequentially, each of the reference signals added to the window width to a second comparator;
counting a first number of times a first output of the first comparator exceeds the reference signals;
counting a second number of times a second output of the second comparator exceeds the reference signals added to the window width; and
calibrating an energy threshold of the first comparator based on the window based spectrum measurements.
PCT/IB2015/056381 2014-09-02 2015-08-24 Window-based spectrum measurement in a spectral ct detector WO2016034976A1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US15/502,788 US10788594B2 (en) 2014-09-02 2015-08-24 Window-based spectrum measurement in a spectral CT detector
EP15771262.1A EP3195017B1 (en) 2014-09-02 2015-08-24 Window-based spectrum measurement in a spectral ct detector
CN201580047228.9A CN106687825B (en) 2014-09-02 2015-08-24 Window-based spectral measurement in spectral CT detectors

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462044550P 2014-09-02 2014-09-02
US62/044,550 2014-09-02

Publications (1)

Publication Number Publication Date
WO2016034976A1 true WO2016034976A1 (en) 2016-03-10

Family

ID=54207628

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2015/056381 WO2016034976A1 (en) 2014-09-02 2015-08-24 Window-based spectrum measurement in a spectral ct detector

Country Status (4)

Country Link
US (1) US10788594B2 (en)
EP (1) EP3195017B1 (en)
CN (1) CN106687825B (en)
WO (1) WO2016034976A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020228935A1 (en) * 2019-05-13 2020-11-19 Direct Conversion Ab Method of reading out data in a radiation detector, radiation detector and imaging apparatus

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7370989B2 (en) * 2018-01-31 2023-10-30 コーニンクレッカ フィリップス エヌ ヴェ a non-spectral computed tomography (CT) scanner configured to generate spectral volumetric image data;
JP7095328B2 (en) * 2018-03-15 2022-07-05 富士電機株式会社 Radiation measuring device
EP3815046A1 (en) * 2018-06-29 2021-05-05 Koninklijke Philips N.V. Imaging system configured to generate non-spectral volumetric image data from a kvp switching multi-energy acquisition
CN110988961B (en) * 2019-12-11 2021-09-07 湖北锐世数字医学影像科技有限公司 Signal processing method and device and detection system

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0483753A2 (en) * 1990-10-30 1992-05-06 Shimadzu Corporation X-ray spectrometer
US20110121980A1 (en) * 2003-07-12 2011-05-26 Radiation Watch Limited, LLC Ionising radiation detector

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1204403A (en) * 1995-10-31 1999-01-06 比奥特雷斯公司 Ultralow background multiple photon detector
JP4279798B2 (en) * 2004-04-02 2009-06-17 財團法人国家衛生研究院 Apparatus and method for characterizing the time constant of peak and decay periods by digitizing gamma ray energy without using an analog / digital converter
JP2008538971A (en) 2005-04-29 2008-11-13 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ Energy-resolved photon counting for CT
WO2008146218A2 (en) * 2007-06-01 2008-12-04 Koninklijke Philips Electronics N.V. Spectral photon counting detector
US7696483B2 (en) * 2007-08-10 2010-04-13 General Electric Company High DQE photon counting detector using statistical recovery of pile-up events
US20110036989A1 (en) * 2008-04-30 2011-02-17 Koninklijke Philips Electronics N.V. Counting detector
CN102076263B (en) * 2008-06-30 2013-06-19 皇家飞利浦电子股份有限公司 Spectral ct
EP2296550B1 (en) * 2008-07-07 2018-03-28 Koninklijke Philips N.V. K-edge imaging
JP5604504B2 (en) * 2009-03-25 2014-10-08 コーニンクレッカ フィリップス エヌ ヴェ Imager detector array detector tile and method
US8384038B2 (en) 2009-06-24 2013-02-26 General Electric Company Readout electronics for photon counting and energy discriminating detectors
US8847169B2 (en) * 2010-05-25 2014-09-30 The Hong Kong University Of Science And Technology Quantum-limited highly linear CMOS detector for computer tomography
CN202334490U (en) * 2011-06-09 2012-07-11 中国科学院西安光学精密机械研究所 Acquisition card for time-resolved photon counting imaging
CN102323959B (en) * 2011-06-09 2013-04-17 中国科学院西安光学精密机械研究所 Capture card for time-resolved photon counting imaging
US9301378B2 (en) * 2011-10-19 2016-03-29 Koninklijke Philips N.V. Photon counting detector
KR20140087246A (en) * 2012-12-28 2014-07-09 삼성전자주식회사 X-ray image apparatus and control method for the same
US9488739B2 (en) * 2013-12-18 2016-11-08 The Board Of Trustees Of The Leland Stanford Junior University Spectral imaging system and method

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0483753A2 (en) * 1990-10-30 1992-05-06 Shimadzu Corporation X-ray spectrometer
US20110121980A1 (en) * 2003-07-12 2011-05-26 Radiation Watch Limited, LLC Ionising radiation detector

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ALVAREZ ET AL.: "Energy-selective reconstructions in x-ray computerized tomography", PHYS. MED. BIOL., vol. 21, 1976, pages 733 - 44

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020228935A1 (en) * 2019-05-13 2020-11-19 Direct Conversion Ab Method of reading out data in a radiation detector, radiation detector and imaging apparatus
CN113811794A (en) * 2019-05-13 2021-12-17 直接转换公司 Method of reading out data in a radiation detector, radiation detector and imaging device
CN113811794B (en) * 2019-05-13 2024-04-26 直接转换公司 Method for reading out data in a radiation detector, radiation detector and imaging device

Also Published As

Publication number Publication date
CN106687825A (en) 2017-05-17
US10788594B2 (en) 2020-09-29
EP3195017B1 (en) 2020-07-22
US20170234996A1 (en) 2017-08-17
CN106687825B (en) 2020-06-23
EP3195017A1 (en) 2017-07-26

Similar Documents

Publication Publication Date Title
EP3195017B1 (en) Window-based spectrum measurement in a spectral ct detector
EP3290959B1 (en) Photon counting detector
US7696483B2 (en) High DQE photon counting detector using statistical recovery of pile-up events
JP6335120B2 (en) Detector array and method for detecting photons
US7480362B2 (en) Method and apparatus for spectral computed tomography
CN110383108B (en) X-ray detector system based on photon counting
US9335424B2 (en) Spectral photon counting detector
US9841389B2 (en) Photon-counting type X-ray computed tomography apparatus and method
EP3479145B1 (en) Photon-counting computed tomography
US20140328465A1 (en) X-ray detector
JP6145517B2 (en) Imaging system for adaptive persistent current compensation and adaptive persistent current compensation method for photon counting detector
JP2015516832A (en) Conventional imaging with an imaging system with a photon counting detector
US9405018B2 (en) Radiographic apparatus for detecting photons with offset correction
WO2008146218A2 (en) Spectral photon counting detector
EP3368918B1 (en) Ct system and ct method
CN109196957B (en) Device for generating X-rays

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 15771262

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

REEP Request for entry into the european phase

Ref document number: 2015771262

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2015771262

Country of ref document: EP