WO2015191972A3 - Omega-carboxylated carboxylic acids and derivities - Google Patents

Omega-carboxylated carboxylic acids and derivities Download PDF

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Publication number
WO2015191972A3
WO2015191972A3 PCT/US2015/035511 US2015035511W WO2015191972A3 WO 2015191972 A3 WO2015191972 A3 WO 2015191972A3 US 2015035511 W US2015035511 W US 2015035511W WO 2015191972 A3 WO2015191972 A3 WO 2015191972A3
Authority
WO
WIPO (PCT)
Prior art keywords
omega
derivities
carboxylic acids
carboxylated
carboxylated carboxylic
Prior art date
Application number
PCT/US2015/035511
Other languages
French (fr)
Other versions
WO2015191972A2 (en
Inventor
Ramon Gonzalez
James M. CLOMBURG
Original Assignee
William Marsh Rice University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by William Marsh Rice University filed Critical William Marsh Rice University
Publication of WO2015191972A2 publication Critical patent/WO2015191972A2/en
Publication of WO2015191972A3 publication Critical patent/WO2015191972A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)

Abstract

Omega functionalized chemicals are made using a reverse beta oxidation cycle either by beginning with particular primers or by omega functionalization of β-oxidation intermediate(s)/product(s). Bacteria and methods for same are provided.
PCT/US2015/035511 2014-06-12 2015-06-12 Omega-carboxylated carboxylic acids and derivities WO2015191972A2 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201462011474P 2014-06-12 2014-06-12
US201462011465P 2014-06-12 2014-06-12
US62/011,465 2014-06-12
US62/011,474 2014-06-12
US201462012113P 2014-06-13 2014-06-13
US62/012,113 2014-06-13

Publications (2)

Publication Number Publication Date
WO2015191972A2 WO2015191972A2 (en) 2015-12-17
WO2015191972A3 true WO2015191972A3 (en) 2016-01-14

Family

ID=54834136

Family Applications (3)

Application Number Title Priority Date Filing Date
PCT/US2015/034629 WO2015191422A1 (en) 2014-06-12 2015-06-08 Omega-hydroxylated carboxylic acids
PCT/US2015/035664 WO2016007258A1 (en) 2014-06-12 2015-06-12 Omega-aminated carboxylic acids
PCT/US2015/035511 WO2015191972A2 (en) 2014-06-12 2015-06-12 Omega-carboxylated carboxylic acids and derivities

Family Applications Before (2)

Application Number Title Priority Date Filing Date
PCT/US2015/034629 WO2015191422A1 (en) 2014-06-12 2015-06-08 Omega-hydroxylated carboxylic acids
PCT/US2015/035664 WO2016007258A1 (en) 2014-06-12 2015-06-12 Omega-aminated carboxylic acids

Country Status (1)

Country Link
WO (3) WO2015191422A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10450593B2 (en) 2014-01-27 2019-10-22 William Marsh Rice University Type II fatty acid synthesis enzymes in reverse β-oxidation
US20180066296A9 (en) * 2015-12-04 2018-03-08 Invista North America S.A.R.L. Methods and materials for producing 7-carbon monomers
WO2017096310A1 (en) 2015-12-04 2017-06-08 Invista North America S.A.R.L. Methods and materials for producing 7-carbon monomers
EP3430151A4 (en) 2016-03-16 2020-09-02 William Marsh Rice University Microbial synthesis of isoprenoid precursors, isoprenoids and derivatives including prenylated aromatics compounds
CN107299072B (en) * 2017-08-02 2020-11-06 江南大学 Engineering bacterium and application thereof
CN111593079B (en) * 2019-02-21 2023-08-01 上海凯赛生物技术股份有限公司 Method for improving fermentation conversion rate of long-chain dibasic acid
CN110713962B (en) * 2019-09-06 2022-06-21 南京农业大学 Genetic engineering bacterium for high-yield production of malonyl coenzyme A and construction method and application thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009078973A2 (en) * 2007-12-13 2009-06-25 Glycos Biotechnologies, Incorporated Microbial conversion of oils and fatty acids to high-value chemicals
WO2013036812A1 (en) * 2011-09-07 2013-03-14 William Marsh Rice University Functionalized carboxylic acids and alcohols by riverse fatty acid oxidation

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1626089A1 (en) * 2004-08-09 2006-02-15 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Lipid metabolic and signalling pathways in the epidermis
US20110020888A1 (en) * 2006-12-15 2011-01-27 Biofuelchem Co., Ltd. METHOD FOR PREPARING BUTANOL THROUGH BUTYRYL-CoA AS AN INTERMEDIATE USING BACTERIA
DE102007060705A1 (en) * 2007-12-17 2009-06-18 Evonik Degussa Gmbh ω-aminocarboxylic acids or their lactams, producing, recombinant cells
WO2010022763A1 (en) * 2008-08-25 2010-03-04 Metabolic Explorer Method for the preparation of 2-hydroxy-isobutyrate
ES2505115T3 (en) * 2008-10-28 2014-10-09 Ls9, Inc. Methods to produce fatty alcohols
US9085766B2 (en) * 2010-05-21 2015-07-21 Cornell University Methods of producing recombinant heme-binding proteins and uses thereof
US8669379B2 (en) * 2011-02-25 2014-03-11 Massachusetts Institute Of Technology Microbial production of 3,4-dihydroxybutyrate (3,4-DHBA), 2,3-dihydroxybutyrate (2,3-DHBA) and 3-hydroxybutyrolactone (3-HBL)
WO2012174451A1 (en) * 2011-06-17 2012-12-20 Invista Technologies S.A.R.L. Use of hydrolases to increase monomer content in waste stream
US8349587B2 (en) * 2011-10-31 2013-01-08 Ginkgo Bioworks, Inc. Methods and systems for chemoautotrophic production of organic compounds

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009078973A2 (en) * 2007-12-13 2009-06-25 Glycos Biotechnologies, Incorporated Microbial conversion of oils and fatty acids to high-value chemicals
WO2013036812A1 (en) * 2011-09-07 2013-03-14 William Marsh Rice University Functionalized carboxylic acids and alcohols by riverse fatty acid oxidation

Also Published As

Publication number Publication date
WO2015191422A1 (en) 2015-12-17
WO2016007258A1 (en) 2016-01-14
WO2015191972A2 (en) 2015-12-17
WO2016007258A9 (en) 2016-03-10

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