WO2015162306A8 - Method for the surface treatment of a biocorrodable implant - Google Patents

Method for the surface treatment of a biocorrodable implant Download PDF

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Publication number
WO2015162306A8
WO2015162306A8 PCT/EP2015/061210 EP2015061210W WO2015162306A8 WO 2015162306 A8 WO2015162306 A8 WO 2015162306A8 EP 2015061210 W EP2015061210 W EP 2015061210W WO 2015162306 A8 WO2015162306 A8 WO 2015162306A8
Authority
WO
WIPO (PCT)
Prior art keywords
implant
biocorrodable
surface treatment
subject
working electrode
Prior art date
Application number
PCT/EP2015/061210
Other languages
German (de)
French (fr)
Other versions
WO2015162306A1 (en
Inventor
Volkmar Neubert
Original Assignee
Syntellix Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to AU2015250774A priority Critical patent/AU2015250774A1/en
Priority to EP15726055.5A priority patent/EP3134563A1/en
Priority to BR112016024664A priority patent/BR112016024664A2/en
Priority to CN201580021762.2A priority patent/CN106456839A/en
Priority to KR1020167032662A priority patent/KR20170023799A/en
Priority to JP2016564034A priority patent/JP2017519538A/en
Application filed by Syntellix Ag filed Critical Syntellix Ag
Priority to SG11201608850RA priority patent/SG11201608850RA/en
Priority to RU2016144709A priority patent/RU2016144709A/en
Priority to CA2946676A priority patent/CA2946676A1/en
Publication of WO2015162306A1 publication Critical patent/WO2015162306A1/en
Publication of WO2015162306A8 publication Critical patent/WO2015162306A8/en
Priority to IL248450A priority patent/IL248450A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25D—PROCESSES FOR THE ELECTROLYTIC OR ELECTROPHORETIC PRODUCTION OF COATINGS; ELECTROFORMING; APPARATUS THEREFOR
    • C25D21/00—Processes for servicing or operating cells for electrolytic coating
    • C25D21/12—Process control or regulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/84—Fasteners therefor or fasteners being internal fixation devices
    • A61B17/86—Pins or screws or threaded wires; nuts therefor
    • A61B17/866—Material or manufacture
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/04—Metals or alloys
    • A61L27/047—Other specific metals or alloys not covered by A61L27/042 - A61L27/045 or A61L27/06
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/30—Inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/30—Inorganic materials
    • A61L27/306—Other specific inorganic materials not covered by A61L27/303 - A61L27/32
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/02—Inorganic materials
    • A61L31/022—Metals or alloys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/082—Inorganic materials
    • A61L31/088—Other specific inorganic materials not covered by A61L31/084 or A61L31/086
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148—Materials at least partially resorbable by the body
    • C—CHEMISTRY; METALLURGY
    • C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
    • C22C—ALLOYS
    • C22C23/00—Alloys based on magnesium
    • C22C23/06—Alloys based on magnesium with a rare earth metal as the next major constituent
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25D—PROCESSES FOR THE ELECTROLYTIC OR ELECTROPHORETIC PRODUCTION OF COATINGS; ELECTROFORMING; APPARATUS THEREFOR
    • C25D11/00—Electrolytic coating by surface reaction, i.e. forming conversion layers
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25D—PROCESSES FOR THE ELECTROLYTIC OR ELECTROPHORETIC PRODUCTION OF COATINGS; ELECTROFORMING; APPARATUS THEREFOR
    • C25D5/00—Electroplating characterised by the process; Pretreatment or after-treatment of workpieces
    • C25D5/18—Electroplating using modulated, pulsed or reversing current
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25D—PROCESSES FOR THE ELECTROLYTIC OR ELECTROPHORETIC PRODUCTION OF COATINGS; ELECTROFORMING; APPARATUS THEREFOR
    • C25D9/00—Electrolytic coating other than with metals
    • C25D9/04—Electrolytic coating other than with metals with inorganic materials
    • C25D9/08—Electrolytic coating other than with metals with inorganic materials by cathodic processes
    • C25D9/12—Electrolytic coating other than with metals with inorganic materials by cathodic processes on light metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00389—The prosthesis being coated or covered with a particular material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/18—Modification of implant surfaces in order to improve biocompatibility, cell growth, fixation of biomolecules, e.g. plasma treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/12—Materials or treatment for tissue regeneration for dental implants or prostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/24—Materials or treatment for tissue regeneration for joint reconstruction

Abstract

The subject of the present invention is a method for the surface treatment of a biocorrodable implant by means of electrochemical reactions, comprising the steps of: a) providing an implant of a biocorrodable magnesium alloy; b) introducing the implant into an electrolyte with a pH of 9-13; c) electrochemically treating the surface of the implant, wherein the implant serves as the working electrode and there is also a counterelectrode, and wherein the working electrode is alternately polarized cathodically and anodically, the current density being set to -0.1 to -7 mA/cm2 for the cathodic polarization and to 0.1 to 2 mA/cm2 for the anodic polarization. A corresponding implant is also the subject of the invention.
PCT/EP2015/061210 2014-04-23 2015-05-21 Method for the surface treatment of a biocorrodable implant WO2015162306A1 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
EP15726055.5A EP3134563A1 (en) 2014-04-23 2015-05-21 Method for the surface treatment of a biocorrodable implant
BR112016024664A BR112016024664A2 (en) 2014-04-23 2015-05-21 method for surface treatment of a biocorrosive implant
CN201580021762.2A CN106456839A (en) 2014-04-23 2015-05-21 Method for the surface treatment of a biocorrodable implant
KR1020167032662A KR20170023799A (en) 2014-04-23 2015-05-21 Method for the surface treatment of a biocorrodable implant
JP2016564034A JP2017519538A (en) 2014-04-23 2015-05-21 Method for surface treatment of bioerodible implants
AU2015250774A AU2015250774A1 (en) 2014-04-23 2015-05-21 Method for the surface treatment of a biocorrodable implant
SG11201608850RA SG11201608850RA (en) 2014-04-23 2015-05-21 Method for the surface treatment of a biocorrodable implant
RU2016144709A RU2016144709A (en) 2014-04-23 2015-05-21 METHOD FOR SURFACE PROCESSING OF AN IMPLANT AFFECTED BY BIOCORROSION
CA2946676A CA2946676A1 (en) 2014-04-23 2015-05-21 Method for the surface treatment of a biocorrodable implant
IL248450A IL248450A0 (en) 2014-04-23 2016-10-23 Method for the surface treatment of a biocorrodable implant

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE201410105732 DE102014105732B3 (en) 2014-04-23 2014-04-23 Process for the surface treatment of a biocorrodible implant and implant obtained by the process
DE102014105732.5 2014-04-23

Publications (2)

Publication Number Publication Date
WO2015162306A1 WO2015162306A1 (en) 2015-10-29
WO2015162306A8 true WO2015162306A8 (en) 2015-12-17

Family

ID=52693491

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2015/061210 WO2015162306A1 (en) 2014-04-23 2015-05-21 Method for the surface treatment of a biocorrodable implant

Country Status (12)

Country Link
EP (1) EP3134563A1 (en)
JP (1) JP2017519538A (en)
KR (1) KR20170023799A (en)
CN (1) CN106456839A (en)
AU (1) AU2015250774A1 (en)
BR (1) BR112016024664A2 (en)
CA (1) CA2946676A1 (en)
DE (1) DE102014105732B3 (en)
IL (1) IL248450A0 (en)
RU (1) RU2016144709A (en)
SG (1) SG11201608850RA (en)
WO (1) WO2015162306A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102016119234A1 (en) * 2016-10-10 2018-04-12 Syntellix Ag Screw drive with integrated torque lock
CN108553187A (en) * 2018-05-16 2018-09-21 广州市健齿生物科技有限公司 A kind of porous dental implant and manufacturing method of internal combination biodegradable magnesium alloy
CN114571015B (en) * 2022-03-17 2023-08-11 江苏江航智飞机发动机部件研究院有限公司 Precise electrolytic machining method for titanium-aluminum alloy spinal cord fixing nail

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19504386C2 (en) * 1995-02-10 1997-08-28 Univ Dresden Tech Process for the production of a graded coating from calcium phosphate phases and metal oxide phases on metallic implants
DE10029520A1 (en) * 2000-06-21 2002-01-17 Merck Patent Gmbh Coating for metallic implant materials
DE10357281A1 (en) * 2003-12-05 2005-07-14 Hassel, Thomas, Dipl.-Ing. Degradable stent for blood vessel support made of magnesium material, comprises degradation-inhibiting biocompatible coating
US20080097577A1 (en) * 2006-10-20 2008-04-24 Boston Scientific Scimed, Inc. Medical device hydrogen surface treatment by electrochemical reduction
CN100998893B (en) * 2006-12-26 2010-05-12 重庆大学 Biodegradable rare earth magnesium alloy material
DE102008054920A1 (en) * 2008-12-18 2010-07-01 Biotronik Vi Patent Ag Implant and method for producing a layer structure
DE102010027532B8 (en) * 2010-07-16 2014-09-18 Aap Biomaterials Gmbh Process for PEO coating
EP2744532B1 (en) * 2011-08-15 2015-09-16 MeKo Laserstrahl-Materialbearbeitungen e.K. Resorbable stents containing a magnesium alloy

Also Published As

Publication number Publication date
EP3134563A1 (en) 2017-03-01
CN106456839A (en) 2017-02-22
CA2946676A1 (en) 2015-10-29
IL248450A0 (en) 2016-11-30
DE102014105732B3 (en) 2015-04-09
RU2016144709A (en) 2018-05-23
WO2015162306A1 (en) 2015-10-29
AU2015250774A1 (en) 2016-12-01
BR112016024664A2 (en) 2018-06-19
JP2017519538A (en) 2017-07-20
KR20170023799A (en) 2017-03-06
SG11201608850RA (en) 2016-12-29

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