WO2015121355A1 - Flexible medical bag - Google Patents

Flexible medical bag

Info

Publication number
WO2015121355A1
WO2015121355A1 PCT/EP2015/052976 EP2015052976W WO2015121355A1 WO 2015121355 A1 WO2015121355 A1 WO 2015121355A1 EP 2015052976 W EP2015052976 W EP 2015052976W WO 2015121355 A1 WO2015121355 A1 WO 2015121355A1
Authority
WO
Grant status
Application
Patent type
Prior art keywords
sheets
member
edges
superposed
spacer
Prior art date
Application number
PCT/EP2015/052976
Other languages
French (fr)
Inventor
Jean Daval
Samuel TERRASSE
Habib REBERGUE
Original Assignee
Medex
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/10Bag-type containers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/14Details, e.g. provisions for hanging or shape retaining means; Accessories therefor, e.g. inlet or outlet ports, filters or caps
    • A61J1/1493Containers with shape retaining means, e.g. to support the structure of the container during emptying or filling

Abstract

The present invention concerns a storage bag (3) for an aqueous medical solution that can be used in an injection device (2), said bag comprising: - two superposed sheets (31, 32) of flexible material linked along the peripheral edges of same so as to define a storage volume for the aqueous solution, - an access member (33) for conveying the aqueous solution between the inside and the outside of the bag, the access member comprising a proximal end sealed between the superposed sheets, - a connector coupled to a distal end of the access member, remarkable in that the bag further comprises a spacer member (34) for preventing the superposed sheets from sticking completely together when the bag is flattened, in order to keep a channel open for the flow of the aqueous solution to the access member, the spacer member extending into the storage volume between the superposed sheets, and in that the spacer member is secured in a pipe (331) of the access member (33).

Description

POCKET MEDICAL FLEXIBLE

TECHNICAL AREA

The present invention concerns the general technical field of the product of administration to a patient, for example parenterally.

It relates more precisely a flexible container - hereinafter called "pocket" - containing an aqueous solution - in particular contrast media - to be administered to a patient.

OVERVIEW OF THE PRIOR ART

There are known flexible pouches containing an aqueous solution such as a contrast medium for administration to a patient, for example during an examination by medical imaging - such as X-ray imaging or Resonance Imaging magnetic (MRI).

Such a pouch 1 conventionally comprises:

- two superimposed sheets sealed at their periphery to define a Volume 1 1 designed to contain the aqueous solution,

- an outlet pipe 12 sealed between the superposed sheets to define a flow channel of the aqueous solution between the inside and outside of the pouch, and

- a connector (not shown) fixed to the free end of the tubing 12 to allow connection of the bag 1 to a fluid delivery set connected to the patient.

In most cases, administration of the aqueous solution requires transfer between the bag and the patient. This transfer can be performed by gravity or using an injection device as described in FR 2991881, EP 0648513 and EP 0 852 152. It has been shown in Figure 1 a injection device 2 described in the document FR 2991881, which device comprises a housing consisting of two half-shells 21 and 22 hinged to allow their relative displacement between an open position for the introduction of the pocket and a position closed for the injection of the liquid product contained in the pouch. More generally, all the injection devices described in documents FR 2991881, EP 0648513 or EP 0852152 comprises a pocket for receiving the housing. They are based on the use of a fluid motor 23 enveloping the bag 1 and, under pressure, will have the task of propelling the liquid out of the pocket. To facilitate the removal of undesirable air bubbles that may appear in the flexible pouch, the housing is oriented so that the tubing 12 of the pouch 1 opens upward of the housing, as shown in Figure 1 where it is found that the portion of the sheet sealed to the tubing extends at an altitude above the other portions of the sheets.

A disadvantage of existing pockets for the loss of part of the aqueous solution they contain. The loss of a portion of the aqueous solution is related to the injection molding process using the injection device, as will be described in more detail in the following with reference to Figure 1.

Upon injection of the aqueous solution to a patient, the working fluid 23 contained within the housing of the injection device 2 exerts forces on the bag 1 from the walls tending to press them one against the other to propel the liquid from the bag 1. Placing the bag 1 of pressure in the casing is likely to generate a collabage 14 superposed sheets of the pouch.

As illustrated in Figure 1 B, this collabage 14 traps a substantial portion of the aqueous solution contained in the pocket (up to 20% content, equivalent to a dose for a patient).

The collabage preferably phenomenon appears at the end of injection, when the aqueous solution to be injected extends to the bottom of the bag 1: pressure laterally applied by the fluid motor 23 plugs the passage of the liquid on the middle and high parts of the bag 1 forming a tight barrier. This phenomenon does not appear systematically. He was encouraged when it remains in the pocket a volume of aqueous solution corresponding approximately to 1/4 to 1/3 of the total volume about the bag as well as by the induction of a high flow rate (ie a higher flow rate to 4 ml / s) by the injection device.

therefore the collabage phenomenon induces the loss of part of the aqueous solution contained in the bag 1. But when the price of the aqueous solution is important (which is often the case with contrast media), it is preferable to limit the loss. Furthermore, when the collabage phenomenon appears during a contrast injection, it may be necessary to repeat the injection procedure, the patient did not receive a sufficient amount of contrast medium. To overcome these disadvantages, various solutions have been proposed to promote the flow of the aqueous solution to the outside of the bag 1, such as:

- thermoforming superimposed sheets or

- the seed formation on the facing walls of the superposed sheets, as described in US 4,810,451.

However, these solutions are not satisfactory for the following reasons:

- as regards the thermoforming of the pocket, it has the disadvantage of not having a sufficient durability over time, particularly in the case of superposed sheets made of a material having a flexibility of the order of 75shA - such as PVC type superimposed sheets. Indeed, firstly thermoforming may relax over time, and secondly the stacked storage pockets can induce a thermoforming crushing;

- more, thermoforming pocket strongly loses (see completely) efficacy if injected at high pressure;

- as regards the formation of grains on the opposite walls of the superposed sheets, so it is effective when the low-pressure injection of an aqueous solution (e.g., injection by gravity), it is totally ineffective in part of a high-pressure injection with an injection device. Indeed, the size of grains formed in the facing walls of the superposed sheets is too small to avoid the phenomenon of collabage. WO 85/04383 proposes to have an insert in a flexible bag in order to allow to maintain a pocket fluid flow channel outward when the pouch is empty and its walls meet. However, the bag with the proposed insert does not entirely satisfactory. Indeed, the attachment of the insert in the pocket is complicated and needs to be implemented before the sealing of the pocket, which requires a specific manufacturing process. Furthermore, the insert does not prevent the collabage nearby the ladle outlet. On the other hand, the pouch is designed for low-pressure injection of an aqueous solution (e.g., injection by gravity) and is not suitable for a high-pressure injection with an injection device. Finally, the proposed insert has small grooves on its surfaces, increasing the risk that the bag fits into these grooves and y is stuck.

An object of the present invention is therefore to provide a flexible container for storage of an aqueous solution for injection to a patient, said container being designed so as to limit the phenomenon of collabage when used in a device injection, which is simple in its design and is easy to manufacture.

PRESENTATION OF THE INVENTION

To this end, the invention proposes a storage bag for medical aqueous solution - specifically contrast agent - can be used in an injection device - in particular a high pressure injection device (that is to say a pressure preferably greater than one bar, more preferably greater than four bars, and even more preferably greater than fourteen bars) - said pouch comprising:

- two superposed sheets of flexible material joined along their peripheral edges to define a storage volume of the aqueous solution, each superimposed sheet comprising top and bottom edges between a pair of longitudinal edges,

- an access member for conveying the aqueous solution between the inside and outside of the pouch, the access member having a proximal end sealed between the upper edges of the superposed sheets,

- a connector coupled to a distal end of the access member,

- a spacer member to prevent the total plating of the superimposed sheets when the bag is flattened so as to maintain a flow channel of the aqueous solution to the access member, the spacer member extending in the storage volume between the superimposed sheets between the lower and upper edges of the pocket,

wherein the spacer member is seated in a nozzle of the access member.

The timing of the retracting member in the tubing keeps the retracting member in the pocket without the latter does not contain specific fixing means: the pocket itself provides the maintaining in position of the retracting member. The spacer member may then be of very simple design, making possible its manufacture by an inexpensive method such as extrusion. Moreover, the fact that the spacer passes through the pipe ensures the evacuation of fluid through the access member via said tube, by means of maintaining a flow channel passing through the tubing along of the spacer member. In addition, the spacer can be inserted via the tubing in the bag after the manufacture thereof. This allows to implement the invention in the context of existing manufacturing processes. Furthermore, the spacer member being wedged into a position extending into the storage volume between the superimposed sheets between the lower and upper edges of the bag serves to stiffen the pocket and to limit bending thereof.

Is meant within the scope of the present invention, "total plating" of the superposed sheets, a plating thereof over the entire lateral section of the pocket. Preferred but not limiting aspects of the pocket according to the invention are:

- the spacer member may be formed in a more rigid material than the material constituting the superposed sheets; the reader will appreciate that as the section of the superposed sheets, the smaller the rigidity of the material constituting the spacer is greater than the stiffness of the material constituting the superposed sheets;

- each superimposed sheet may comprise upper and lower edges between a pair of longitudinal edges, the proximal end of the access member is sealed between the upper edges of the superposed sheets, the spacer member extending between the longitudinal edges of the superposed sheets from the upper edges toward the lower edges;

- the spacer member may include at least one rod extending through the storage volume between the upper and lower edges of the superimposed sheets;

- the rod may be rectilinear;

- the rod may be curved;

- form in the rod section may be chosen from an X shape, a U-shape, a Y shape and a form O;

- the wand-sectional area may be between 0.1 mm 2 and 50 mm 2, preferably between 0.2 and 10 mm 2, more preferably between 0.2 and 5 mm 2;

- the angles of the portions of the rod extending within the storage volume may be non-protruding; is meant within the scope of this "non-projecting angle," an angle having no pocket tearing capacity;

- the access member may include:

o a base at its proximal end sealed between the superposed sheets, and

o a tubing extending through the base,

the thickness of the base in a direction perpendicular to the planes of the superimposed sheets being greater than or equal to the diameter of the tubing, so that the upper edges of the superposed sheets are spaced by a non-zero distance equal to the thickness of the base; - the spacer member can be fixed in the base of the access member;

- the pouch may also include a seal base between the lower edges of the superposed leaves the base having a non-zero thickness so that the lower edges of the superimposed sheets are spaced apart a distance equal to the thickness of the base;

- the spacer member can be fixed in the socket;

- the spacer is wedged further in a boss formed in the bottom edge of the pocket. The invention also relates to a method of manufacturing a storage bag according to the invention, wherein the spacer member is positioned between the superposed sheets after bonding peripheral edges by inserting said spreader member through tubing in the storage volume defined by the superimposed sheets.

PRESENTATION OF THE FIGURES

Other features and advantages of the invention will become apparent from the following description, which is purely illustrative and not exhaustive and should be read with the accompanying drawings, wherein:

- Figures 1A and 1B are schematic illustrations of an injection device described in document FR 2,991,881,

- Figures 2 to 9 illustrate various embodiments of a storage pocket for aqueous medical solution according to the invention,

- Figures 10 to 1 1 are schematic representations in perspective of a spacer member,

- Figure 12 is a cross-sectional view of various examples of spacer member. EMBODIMENTS DESCRIPTION OF THE INVENTION

We will now describe different embodiments of the flexible container according to the invention. In the various figures, equivalent elements have the same reference numbers.

Referring to Figures 2-9, there is illustrated various examples of flexible containers 3 of the invention. The container 3 comprises two superposed sheets 31, 32, an access member 33 and a (or several) connector (s) (not shown). It further comprises a spacer member 34, and may comprise a base 35.

leaves

The superposed sheets 31, 32 are used to define a volume for containing such an aqueous solution as a contrast medium.

Each sheet 31, 32 may be composed of several layers of laminated thin films in flexible or soft material, possibly transparent or translucent materials such as polymers comprising polyethylene, polypropylene, polyvinyl chloride, ethylene vinyl acetate and preferably thermoplastic materials.

The leaves 31, 32 have a length "L1" and width "11" appropriate and are interconnected at their peripheries, for example, by welding, gluing or any other known to those skilled in the art.

More precisely, in the embodiments illustrated in Figures 2-9, each sheet 31, 32 comprises an upper edge 41, lower edge 42 and two longitudinal edges 43 between the edges of upper 41 and lower 42, the upper edges 41, lower 42 longitudinal and 43 being respectively connected together.

The reader will appreciate that the connection between the peripheral edges 41, 42, 43 of the superposed sheets 31, 32 may be direct - that is to say that the peripheral edges of sheets 31, 32 are directly in contact with the other - or indirect - that is to say an intermediate part extending between the peripheral edges of sheets 31, 32.

Of course the connection between the sheets 31, 32 can be live on some 43 banks and other indirect 41.

For example, in some embodiments (as illustrated in Figures 2-3 and 5-9):

- the longitudinal edges 43 and lower 42 of the sheets 31, 32 are connected directly with each other, while

- the upper edges 41 are indirectly connected to each other, a base 332, access member 33 extending between the upper edges 41 of the superposed sheets 31, 32. In other embodiments (as shown in Figure 4):

- the longitudinal edges 43 of the sheets 31, 32 are connected directly with each other, while

- the upper edges 41 and lower 42 of the sheets 31, 32 are connected indirectly to each other, a part forming a base 35 extending between the lower edges 42 of the sheets 31, 32 and a base 332 of the access member 33 s' extending between the upper edges 41 of the sheets 31, 32.

Access member The access member 33 allows to define a flow channel of the aqueous solution between the inside and outside of the pocket.

The access member may be sealed (preferably by heat welding or by high frequency welding or bonding) between the superposed sheets 31, 32, on the upper edges thereof.

The access member 33 may consist of one (or more) pipe (s) 331. In this case, the proximal end of the (each) manifold 331 is sealed to the upper edges of the superposed sheets 31, 32. Alternatively, the access member 33 may include a base 332 through which extends one (or more) pipe (s) 331. In this case, it is the base 332 which is sealed to the upper edges of the superposed sheets. The base has a length "L2", width "12" and thickness "e" nonzero.

The base can be of different shapes. For example, in the embodiments illustrated in Figures 2-9, the base has a hexagonal shape in section. Is meant within the scope of the present invention, by "length" and "width" of the base 332, the base 332 of dimensions in orthogonal directions contained in a plane parallel to the superposed sheets 31, 32.

Is meant within the scope of the present invention, "thickness" of the base 332, a dimension of the base 332 in a direction perpendicular to the planes of sheets 31, 32, this thickness E defining the spacing between the superposed sheets 31 , 32 at the base 332.

The use of an access member 33 comprises a base 332 keeps the superposed sheets 31, 32 spaced apart by a non-zero distance at their upper edges 41 even when the bag is flattened. This avoids the collabage of the superposed sheets 31, 32 near the manifold 331.

The use of a access member 33 comprises a base 332 allows further to have a surface for anchoring the spacer member 34 which will be described in detail hereinafter.

The distal end of the (each) manifold 331 is connected to (one of the) connector (s).

connector

The (each) connector allows coupling of the bag to a fluid transfer set connected to the patient. The (each) connector comprises a substantially cylindrical body, a locking zone at one end of the body and an interface zone tube to the other end of the body.

An axial passage is provided in the body and the zones for the delivery of liquid to be administered through the connector.

plinth

As illustrated in Figure 4, the bag 3 can optionally comprise a base 35 sealed between the lower edges 42 of the superposed sheets 31, 32. As the base 332, the base 35 can be hexagonal in section. The base 35 preferably has a non-zero thickness e so as to hold the superposed sheets 31, 32 apart at their lower edges 42.

Spacer member

The spacer member 34 is intended to prevent total sealing of the flow path of the aqueous solution between the bottom edges 42 and top 41 of the bag 3 when it is flattened. More specifically, the spacer member 34 avoids the collabage of the superposed sheets 31, 32 maintaining an open feed line of the aqueous solution between the bottom edges 42 and top 41 of the bag 3.

The spacing member 34 extends within the volume defined by the superposed sheets 31, 32. Specifically, the spacer member 34 extends between the bottom edges 42 and top 41 of the bag 3 .

Preferably, the spacer member extends between the superposed sheets 31, 32 of a length substantially equal to the distance between the upper edges 41 and lower 42 of the pocket 3. This prevents the collabage superposed sheets 31 32 the entire length L1 of the pocket 3 to limit losses in aqueous solution. Advantageously, the spacer member 34 is formed in a material more rigid than the material constituting the superposed sheets 31, 32. This allows the spacer 34 to prevent the crushing of the spacer member when flattening of the bag so as to hold open a fluid feed line, even when the pressure exerted on the pocket to flatten it is important (ie typically greater than one bar).

The spacing member 34 may have various shapes. It may for example consist of:

- a single straight strip (see Figures 3 and 4) or a single curved bar (see figure 2),

- a plurality of rods connected to each other (see figures 5, 6 to 1 1) to facilitate their introduction, or

- a plurality of separate strips (see Figures 7-9) to facilitate the flow of the aqueous solution out of the pouch when it is flattened.

The use of a curved rod serves in particular to maximize the area covered by the spacer member so as to facilitate the flow of the aqueous solution out of the pouch when it is flattened. Each rod 34 can have varying cross-sectional shapes. For example and as shown in Figure 12, the shape in the rod section may be an X shape 34a, 34b, 34b a U-shape, a Y-shape or O-shape 34c, 34d. Preferably, the sectional shape of the rod 34 is selected from an X shape, a U shape or a Y These different forms rod section have the advantage of giving the best results. In particular, these cross-sectional shapes possible to ensure the flow of fluid without risking that the pocket it is pinched, as would be the case with grooves on a flat face. Is meant within the scope of the present invention, "O-shape" of a rod, a circular or elliptical shape of the wand, this wand being hollow or solid. Alternatively, each strip 34 may have a triangular, square or rectangular section.

The use of an O-shape to the wand 34 allows to limit the risks of piercing one of the superimposed sheets when the flattening of the pocket.

Whatever shaped retaining section for the (or) strip (s), the angles of the rod portions 34 extending within the volume defined by the superposed sheets are non-protruding. Preferably, the sectional area of the rod is between 0.1 mm 2 and 50mm 2. This ensures the maintenance of a conveyor line from the open aqueous solution.

Each strip can be anchored in the base 332 or the base 35 of the pocket. This avoids the risk of displacement of the spacer member 34 inside the volume defined by the superposed sheets 31, 32.

Alternatively, each rod 34 of the spacer member can be clamped in one (or more) protrusions 36 formed in the edges of the pocket. For example, with reference to Figures 3 and 5, there is illustrated the flexible pouch embodiments wherein the spacer is wedged:

- firstly in a boss 36 formed in the lower edge 42 of the pocket 3, and

- secondly the tubing 331 of the access member 33.

Advantageously, the spacer member may be positioned between the superposed sheets 31, 32 prior to the bonding their peripheral edges 41, 42, 43, or after the connection of the peripheral edges 41, 42, 43. In this case, the spacer member is inserted through the manifold 331 in the storage volume defined by the superposed sheets 31, 32.

The reader will understand that many modifications can be made without materially departing from the novel teachings and advantages described herein.

Accordingly, all such modifications are intended to be included within the scope of the appended claims.

Claims

1. storage pocket (3) for aqueous medical solution for use in an injection device (2), said pouch comprising:
- two superimposed sheets (31, 32) of flexible material joined along their peripheral edges (41, 42, 43) to define a storage volume of the aqueous solution, each superimposed sheet comprising top and bottom edges (41, 42 ) between a pair of longitudinal edges (43),
- an access member (33) for the delivery of the aqueous solution between the inside and outside of the pouch, the access member having a proximal end sealed between the upper edges of the superposed sheets,
- a connector coupled to a distal end of the access member,
- a spacer member (34) for preventing the total plating of the superimposed sheets when the bag is flattened so as to maintain a flow channel of the aqueous solution to the access member,
characterized in that the spacer member extends into the storage volume between the superimposed sheets between the lower edges (42) and upper (41) of the pocket (3), the spacer member being wedged into a manifold (331) of the access member (33).
2. storage bag according to claim 1, wherein the spacer member is formed in a more rigid material than the material of the superposed sheets.
3. storage bag according to any one of claims 1 to 2, wherein the spacer member comprises at least one rod extending through the storage volume between the upper and lower edges of the superimposed sheets.
4. Pocket storage according to claim 3, wherein the rod is rectilinear.
5. storage pocket according to claim 3, wherein the rod is curved.
6. Pocket storage device according to any one of claims 3 to 5, wherein the sectional shape of the rod is selected from an X shape, a U-shape, a Y shape and a shaped O.
7. storage bag according to any one of claims 3 to 5, wherein the sectional area of the rod is between 0.1 mm 2 and 50 mm 2.
8. storage bag according to any preceding claim, wherein the angles of the portions of the rod extending within the storage volume are non-protruding.
9. storage pouch according to any one of claims 1 to 8, wherein the access member comprises:
- a base (332) at its proximal end sealed between the superposed sheets, and
- a pipe (331) extending through the base,
the thickness of the base in a direction perpendicular to the planes of the superimposed sheets being greater than or equal to the diameter of the tubing, so that the upper edges of the superposed sheets are spaced by a non-zero distance equal to the thickness of the based.
10. Pocket storage according to any one of claims 1 to 9, which further comprises a base (35) sealed between the lower edges (42) of superposed sheets the base having a non-zero thickness so that the lower edges of superposed sheets are spaced apart a distance equal to the thickness of the base.
January 1. Storage bag according to claim 10, wherein the spacer member is fixed in the base.
12. storage pocket according to one of claims 1 to 10, wherein the spacer is wedged further into a boss (36) formed in the lower edge (42) of the pocket (3).
13. A method of manufacturing a storage bag according to any one of claims 1 to 12, wherein the spacer member is positioned between the superimposed sheets (31, 32) after the connection of the peripheral edges (41 , 42, 43) by inserting said tubing through a spacer member (331) in the storage volume defined by the superimposed sheets (31, 32).
PCT/EP2015/052976 2014-02-12 2015-02-12 Flexible medical bag WO2015121355A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR1451090A FR3017287A1 (en) 2014-02-12 2014-02-12 flexible medical bag
FR1451090 2014-02-12

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20167024744A KR20160122190A (en) 2014-02-12 2015-02-12 Flexible medical bag
EP20150704007 EP3104825A1 (en) 2014-02-12 2015-02-12 Flexible medical bag

Publications (1)

Publication Number Publication Date
WO2015121355A1 true true WO2015121355A1 (en) 2015-08-20

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ID=50424618

Family Applications (1)

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Country Status (4)

Country Link
EP (1) EP3104825A1 (en)
KR (1) KR20160122190A (en)
FR (1) FR3017287A1 (en)
WO (1) WO2015121355A1 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1985004383A1 (en) * 1984-03-29 1985-10-10 Liqui-Box Corporation Insert for a collapsible container
WO1989003697A1 (en) * 1987-10-22 1989-05-05 Leonard Barry French Collapsible solution container
EP0554988A1 (en) * 1992-02-04 1993-08-11 Material Engineering Technology Laboratory, Inc. Mixing apparatus

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0622614B2 (en) * 1988-06-21 1994-03-30 テルモ株式会社 The blood reservoir

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1985004383A1 (en) * 1984-03-29 1985-10-10 Liqui-Box Corporation Insert for a collapsible container
WO1989003697A1 (en) * 1987-10-22 1989-05-05 Leonard Barry French Collapsible solution container
EP0554988A1 (en) * 1992-02-04 1993-08-11 Material Engineering Technology Laboratory, Inc. Mixing apparatus

Also Published As

Publication number Publication date Type
KR20160122190A (en) 2016-10-21 application
EP3104825A1 (en) 2016-12-21 application
FR3017287A1 (en) 2015-08-14 application

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