WO2014189780A3 - Apparatus and method for forming a nanofiber hydrogel composite - Google Patents

Apparatus and method for forming a nanofiber hydrogel composite Download PDF

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Publication number
WO2014189780A3
WO2014189780A3 PCT/US2014/038344 US2014038344W WO2014189780A3 WO 2014189780 A3 WO2014189780 A3 WO 2014189780A3 US 2014038344 W US2014038344 W US 2014038344W WO 2014189780 A3 WO2014189780 A3 WO 2014189780A3
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WO
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Application
Patent type
Prior art keywords
housing
platform
method
electrospun
nozzle
Prior art date
Application number
PCT/US2014/038344
Other languages
French (fr)
Other versions
WO2014189780A2 (en )
Inventor
Catherine K. Kuo
Jeffrey P. Brown
Original Assignee
Tufts University
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Publication date

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Classifications

    • DTEXTILES; PAPER
    • D01NATURAL OR ARTIFICIAL THREADS OR FIBRES; SPINNING
    • D01DMECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D5/00Formation of filaments, threads, or the like
    • D01D5/18Formation of filaments, threads, or the like by means of rotating spinnerets
    • DTEXTILES; PAPER
    • D01NATURAL OR ARTIFICIAL THREADS OR FIBRES; SPINNING
    • D01DMECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D5/00Formation of filaments, threads, or the like
    • D01D5/0007Electro-spinning
    • D01D5/0061Electro-spinning characterised by the electro-spinning apparatus

Abstract

A method for making an electrospun nano- or micro-fiber hydrogel composite includes a platform suspended within a housing and a motor connected to the housing or platform so as to cause rotation of the housing relative to the platform, or vice versa. The platform supports nozzles that are directed toward a collector formed on an interior surface of the housing. At least one nozzle is configured to discharge an electrospun fiber, and at least one other nozzle is configured to discharge a gellable solution. After multiple revolutions of the housing, the electrospun fiber forms a scaffold that is interspersed with hydrogel and the other discharged substances. This novel method of fabrication yields composites consisting of a variety of materials, structures, biological and chemical components, and mechanical properties that will have utility in a variety of fields including regenerative medicine, tissue engineering, drug delivery, wound healing and more.
PCT/US2014/038344 2013-05-20 2014-05-16 Apparatus and method for forming a nanofiber hydrogel composite WO2014189780A3 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US201361825191 true 2013-05-20 2013-05-20
US61/825,191 2013-05-20

Publications (2)

Publication Number Publication Date
WO2014189780A2 true WO2014189780A2 (en) 2014-11-27
WO2014189780A3 true true WO2014189780A3 (en) 2015-01-15

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PCT/US2014/038344 WO2014189780A3 (en) 2013-05-20 2014-05-16 Apparatus and method for forming a nanofiber hydrogel composite

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WO (1) WO2014189780A3 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106567144A (en) * 2016-11-11 2017-04-19 北京化工大学 Three-dimensional coaxial spinning apparatus

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060228435A1 (en) * 2004-04-08 2006-10-12 Research Triangle Insitute Electrospinning of fibers using a rotatable spray head
US20080237934A1 (en) * 2005-05-03 2008-10-02 The University Of Akron Method and Device For Producing Electrospun Fibers and Fibers Produced Thereby
US20110156319A1 (en) * 2008-10-02 2011-06-30 Takahiro Kurokawa Method and apparatus for producing nanofibers
US20120034461A1 (en) * 2009-03-31 2012-02-09 The Science And Technology Facilities Council Electrospinning nozzle
US20120040461A1 (en) * 2009-02-23 2012-02-16 Beachley Vince Z Fabrication of nanofiber reinforced structures for tissue engineering
US20120304613A1 (en) * 2011-02-07 2012-12-06 Ed Peno Split fiber producing devices and methods for the production of microfibers and nanofibers

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060228435A1 (en) * 2004-04-08 2006-10-12 Research Triangle Insitute Electrospinning of fibers using a rotatable spray head
US20080237934A1 (en) * 2005-05-03 2008-10-02 The University Of Akron Method and Device For Producing Electrospun Fibers and Fibers Produced Thereby
US20110156319A1 (en) * 2008-10-02 2011-06-30 Takahiro Kurokawa Method and apparatus for producing nanofibers
US20120040461A1 (en) * 2009-02-23 2012-02-16 Beachley Vince Z Fabrication of nanofiber reinforced structures for tissue engineering
US20120034461A1 (en) * 2009-03-31 2012-02-09 The Science And Technology Facilities Council Electrospinning nozzle
US20120304613A1 (en) * 2011-02-07 2012-12-06 Ed Peno Split fiber producing devices and methods for the production of microfibers and nanofibers

Also Published As

Publication number Publication date Type
WO2014189780A2 (en) 2014-11-27 application

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