WO2014160628A3 - Articles and methods for preventing and treating dermatologic adverse events - Google Patents

Articles and methods for preventing and treating dermatologic adverse events Download PDF

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Publication number
WO2014160628A3
WO2014160628A3 PCT/US2014/031545 US2014031545W WO2014160628A3 WO 2014160628 A3 WO2014160628 A3 WO 2014160628A3 US 2014031545 W US2014031545 W US 2014031545W WO 2014160628 A3 WO2014160628 A3 WO 2014160628A3
Authority
WO
WIPO (PCT)
Prior art keywords
preventing
methods
articles
adverse events
treating dermatologic
Prior art date
Application number
PCT/US2014/031545
Other languages
French (fr)
Other versions
WO2014160628A2 (en
Inventor
Mario E. LACOUTURE
Ghassan Khaled ABOU-ALFA
Original Assignee
Sloan-Kettering Institute For Cancer Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sloan-Kettering Institute For Cancer Research filed Critical Sloan-Kettering Institute For Cancer Research
Priority to US14/888,392 priority Critical patent/US20160101114A1/en
Priority to EP14775469.1A priority patent/EP2978412A2/en
Publication of WO2014160628A2 publication Critical patent/WO2014160628A2/en
Publication of WO2014160628A3 publication Critical patent/WO2014160628A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The present invention provides articles and methods for preventing or treating dermatologic adverse events.
PCT/US2014/031545 2013-03-25 2014-03-24 Articles and methods for preventing and treating dermatologic adverse events WO2014160628A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US14/888,392 US20160101114A1 (en) 2013-03-25 2014-03-24 Articles and methods for preventing and treating dermatologic adverse events
EP14775469.1A EP2978412A2 (en) 2013-03-25 2014-03-24 Articles and methods for preventing and treating dermatologic adverse events

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361804907P 2013-03-25 2013-03-25
US61/804,907 2013-03-25

Publications (2)

Publication Number Publication Date
WO2014160628A2 WO2014160628A2 (en) 2014-10-02
WO2014160628A3 true WO2014160628A3 (en) 2014-12-04

Family

ID=51625660

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2014/031545 WO2014160628A2 (en) 2013-03-25 2014-03-24 Articles and methods for preventing and treating dermatologic adverse events

Country Status (3)

Country Link
US (1) US20160101114A1 (en)
EP (1) EP2978412A2 (en)
WO (1) WO2014160628A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3081484A1 (en) 2017-11-01 2019-05-09 Clexio Biosciences Ltd. Finished fibrous structures and methods of their use and preparation
WO2019114705A1 (en) 2017-12-13 2019-06-20 上海小午医药科技有限公司 Method for preventing or treating disease related to egfr inhibition
CN114028568A (en) * 2018-04-16 2022-02-11 上海岸阔医药科技有限公司 Method for preventing or treating side effects of tumor therapy
WO2021073535A1 (en) * 2019-10-16 2021-04-22 上海岸阔医药科技有限公司 Method for preventing or treating diseases associated with administration of vegfr and/or vegf inhibitor

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5229130A (en) * 1991-12-20 1993-07-20 Cygnus Therapeutics Systems Vegetable oil-based skin permeation enhancer compositions, and associated methods and systems
US20080138391A1 (en) * 2006-12-08 2008-06-12 Dario Norberto Carrara Skin-friendly drug complexes for transdermal administration
US20100003353A1 (en) * 2008-06-11 2010-01-07 Biochemics, Inc. Control of Blood Vessel Physiology to Treat Skin Disorders
US20100305209A1 (en) * 2008-07-18 2010-12-02 Biomod Collection Inc. Articles of Manufacture Releasing an Active Ingredient
US20110212157A1 (en) * 2008-06-26 2011-09-01 Anterios, Inc. Dermal delivery

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5229130A (en) * 1991-12-20 1993-07-20 Cygnus Therapeutics Systems Vegetable oil-based skin permeation enhancer compositions, and associated methods and systems
US20080138391A1 (en) * 2006-12-08 2008-06-12 Dario Norberto Carrara Skin-friendly drug complexes for transdermal administration
US20100003353A1 (en) * 2008-06-11 2010-01-07 Biochemics, Inc. Control of Blood Vessel Physiology to Treat Skin Disorders
US20110212157A1 (en) * 2008-06-26 2011-09-01 Anterios, Inc. Dermal delivery
US20100305209A1 (en) * 2008-07-18 2010-12-02 Biomod Collection Inc. Articles of Manufacture Releasing an Active Ingredient

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JANI ET AL.: "A review on delivery of antihypertensive drugs through transdermal systems;", INTL. J. PHARM. CHEM. SCI.;, vol. 1, no. 4, August 2012 (2012-08-01), pages 1805 - 1818 *
SELVAM ET AL.: "Transdermal drug delivery systems for antihypertensive drugs- a review;", INTL. J. PHARM. BIOMED. RES.;, vol. 1, no. 1, 24 February 2010 (2010-02-24), pages 1 - 8 *
VENKATRAMAN ET AL.: "Skin adhesives and skin adhesion: transdermal drug delivery systems;", BIOMATERIALS, vol. 19, 8 January 1998 (1998-01-08), pages 1119 - 1136 *

Also Published As

Publication number Publication date
US20160101114A1 (en) 2016-04-14
EP2978412A2 (en) 2016-02-03
WO2014160628A2 (en) 2014-10-02

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