WO2014152536A2 - Inhibitors of leukotriene a4 hydrolase - Google Patents
Inhibitors of leukotriene a4 hydrolase Download PDFInfo
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- WO2014152536A2 WO2014152536A2 PCT/US2014/027449 US2014027449W WO2014152536A2 WO 2014152536 A2 WO2014152536 A2 WO 2014152536A2 US 2014027449 W US2014027449 W US 2014027449W WO 2014152536 A2 WO2014152536 A2 WO 2014152536A2
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- 0 CC*c1c(C)c(C)c(*)c(*)c1*C* Chemical compound CC*c1c(C)c(C)c(*)c(*)c1*C* 0.000 description 3
- VTDIWMPYBAVEDY-UHFFFAOYSA-N CCCN1CCCCC1 Chemical compound CCCN1CCCCC1 VTDIWMPYBAVEDY-UHFFFAOYSA-N 0.000 description 1
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- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
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- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
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- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
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- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
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- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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Priority Applications (11)
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MX2015011676A MX2015011676A (en) | 2013-03-14 | 2014-03-14 | Inhibitors of leukotriene a4 hydrolase. |
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RU2015137977A RU2690489C2 (en) | 2013-03-14 | 2014-03-14 | Leukotriene a4-hydrolase inhibitors |
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AU2019204753A AU2019204753A1 (en) | 2013-03-14 | 2019-07-02 | Inhibitors of leukotriene a4 hydrolase |
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- 2014-03-14 WO PCT/US2014/027449 patent/WO2014152536A2/en active Application Filing
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Also Published As
Publication number | Publication date |
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US20160068522A1 (en) | 2016-03-10 |
AU2014239585A1 (en) | 2015-09-24 |
US9822106B2 (en) | 2017-11-21 |
JP2016516043A (en) | 2016-06-02 |
EP2968265A2 (en) | 2016-01-20 |
US20180118735A1 (en) | 2018-05-03 |
CA2906086A1 (en) | 2014-09-25 |
RU2015137977A3 (en) | 2018-03-27 |
MX2015011676A (en) | 2016-04-25 |
WO2014152536A3 (en) | 2014-11-27 |
BR112015022227A2 (en) | 2017-07-18 |
AU2019204753A1 (en) | 2019-07-18 |
JP6562898B2 (en) | 2019-08-21 |
RU2015137977A (en) | 2017-04-20 |
KR20150131211A (en) | 2015-11-24 |
AU2014239585B2 (en) | 2019-04-04 |
EP2968265A4 (en) | 2016-12-28 |
RU2690489C2 (en) | 2019-06-04 |
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