WO2014132135A3 - Method of preparing 2-((5z,8z,11 z,14z,17z)-icosa-5,8,1 1,14,17-pentaenyloxy)butanoic acid - Google Patents

Method of preparing 2-((5z,8z,11 z,14z,17z)-icosa-5,8,1 1,14,17-pentaenyloxy)butanoic acid Download PDF

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Publication number
WO2014132135A3
WO2014132135A3 PCT/IB2014/000954 IB2014000954W WO2014132135A3 WO 2014132135 A3 WO2014132135 A3 WO 2014132135A3 IB 2014000954 W IB2014000954 W IB 2014000954W WO 2014132135 A3 WO2014132135 A3 WO 2014132135A3
Authority
WO
WIPO (PCT)
Prior art keywords
pentaenyloxy
icosa
preparing
butanoic acid
butanoic
Prior art date
Application number
PCT/IB2014/000954
Other languages
French (fr)
Other versions
WO2014132135A2 (en
Inventor
Tore Skjaeret
Ragnar Hovland
Original Assignee
Pronova Biopharma Norge As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pronova Biopharma Norge As filed Critical Pronova Biopharma Norge As
Priority to KR1020157026596A priority Critical patent/KR102179351B1/en
Priority to US14/770,870 priority patent/US9365482B2/en
Priority to CN201480018978.9A priority patent/CN105102414B/en
Priority to ES14730991.8T priority patent/ES2619714T3/en
Priority to EP14730991.8A priority patent/EP2961727B1/en
Priority to DK14730991.8T priority patent/DK2961727T3/en
Priority to JP2015559573A priority patent/JP6325580B2/en
Priority to AU2014222390A priority patent/AU2014222390B2/en
Publication of WO2014132135A2 publication Critical patent/WO2014132135A2/en
Publication of WO2014132135A3 publication Critical patent/WO2014132135A3/en
Priority to HRP20170383TT priority patent/HRP20170383T1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/367—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/47—Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

A method of preparing 2-((5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenyloxy)butanoic acid is provided.
PCT/IB2014/000954 2013-02-28 2014-02-27 Methods of preparing fatty acid derivatives WO2014132135A2 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
KR1020157026596A KR102179351B1 (en) 2013-02-28 2014-02-27 Method of Preparing 2-((5Z,8Z,11Z,14Z,17Z)-Icosa-5,8,11,14,17-Pentaenyloxy)Butanoic Acid
US14/770,870 US9365482B2 (en) 2013-02-28 2014-02-27 Methods of preparing fatty acid derivatives
CN201480018978.9A CN105102414B (en) 2013-02-28 2014-02-27 The method for preparing 2 (the alkenyl epoxide of (5Z, 8Z, 11Z, 14Z, 17Z) 20 carbon 5,8,11,14,17 5) butyric acid
ES14730991.8T ES2619714T3 (en) 2013-02-28 2014-02-27 Method of preparing 2 - ((5Z, 8Z, 11Z, 14Z, 17Z) -icosa-5,8,11,14,17-pentayloxy) butanoic acid
EP14730991.8A EP2961727B1 (en) 2013-02-28 2014-02-27 Method of preparing 2-((5z,8z,11z,14z,17z)-icosa-5,8,11,14,17-pentaenyloxy)butanoic acid
DK14730991.8T DK2961727T3 (en) 2013-02-28 2014-02-27 Process for Preparation of 2 - ((5Z, 8Z, 11Z, 14Z, 17Z) -icosa-5,8,11,14,17-pentaenyloxy) -butanoic acid
JP2015559573A JP6325580B2 (en) 2013-02-28 2014-02-27 Method for preparing 2-((5Z, 8Z, 11Z, 14Z, 17Z) -icosa-5,8,11,14,17-pentaenyloxy) butanoic acid
AU2014222390A AU2014222390B2 (en) 2013-02-28 2014-02-27 Method of preparing 2-((5Z,8Z,11 Z,14Z,17Z)-icosa-5,8,1 1,14,17-pentaenyloxy)butanoic acid
HRP20170383TT HRP20170383T1 (en) 2013-02-28 2017-03-08 Method of preparing 2-((5z,8z,11z,14z,17z)-icosa-5,8,11,14,17-pentaenyloxy)butanoic acid

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361770601P 2013-02-28 2013-02-28
US61/770,601 2013-02-28

Publications (2)

Publication Number Publication Date
WO2014132135A2 WO2014132135A2 (en) 2014-09-04
WO2014132135A3 true WO2014132135A3 (en) 2014-11-27

Family

ID=50972746

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2014/000954 WO2014132135A2 (en) 2013-02-28 2014-02-27 Methods of preparing fatty acid derivatives

Country Status (15)

Country Link
US (1) US9365482B2 (en)
EP (1) EP2961727B1 (en)
JP (2) JP6325580B2 (en)
KR (1) KR102179351B1 (en)
CN (2) CN107673964B (en)
AR (1) AR094942A1 (en)
AU (1) AU2014222390B2 (en)
DK (1) DK2961727T3 (en)
ES (1) ES2619714T3 (en)
HR (1) HRP20170383T1 (en)
HU (1) HUE031763T2 (en)
PL (1) PL2961727T3 (en)
PT (1) PT2961727T (en)
TW (1) TWI624453B (en)
WO (1) WO2014132135A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112020011431A2 (en) 2017-12-06 2020-11-24 Basf As fatty acid derivatives for the treatment of non-alcoholic steatohepatitis
US20210290576A1 (en) 2018-05-23 2021-09-23 Northsea Therapeutics B.V. Structurally modified fatty acids for improving glycemic control and treating inflammatory bowel disease
CN116829139A (en) 2020-12-22 2023-09-29 北海医疗私人有限公司 Combination therapeutic agent comprising oxygen-containing structurally enhanced fatty acids for the treatment of non-alcoholic steatohepatitis

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010128401A1 (en) * 2009-05-08 2010-11-11 Pronova Biopharma Norge As Polyunsaturated fatty acids for the treatment of diseases related to cardiovascular, metabolic and inflammatory disease areas

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0791217B2 (en) * 1988-11-21 1995-10-04 宇部興産株式会社 Process for producing optically active 2-phenoxybutanoic acid
RU2009121007A (en) * 2006-11-03 2010-12-10 Пронова Биофарма Норге Ас (No) FAT ALCOHOLS
WO2009134147A1 (en) * 2008-05-02 2009-11-05 Pronova Biopharma Norge As Lipid compositions containing derivatives of epa and dha an their use thereof
WO2010033466A1 (en) * 2008-09-16 2010-03-25 Phenomix Corporation Macrocyclic inhibitors of hepatitis c protease
EP2248798A1 (en) * 2009-05-08 2010-11-10 Pronova BioPharma Norge AS Novel lipid compounds
EP2635270B1 (en) * 2010-11-05 2016-12-21 Pronova BioPharma Norge AS Methods of treatment using lipid compounds

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010128401A1 (en) * 2009-05-08 2010-11-11 Pronova Biopharma Norge As Polyunsaturated fatty acids for the treatment of diseases related to cardiovascular, metabolic and inflammatory disease areas

Also Published As

Publication number Publication date
KR20160002732A (en) 2016-01-08
ES2619714T3 (en) 2017-06-26
CN105102414B (en) 2017-08-04
JP2018127479A (en) 2018-08-16
AU2014222390B2 (en) 2018-05-31
US20160009625A1 (en) 2016-01-14
AR094942A1 (en) 2015-09-09
PL2961727T3 (en) 2017-06-30
HRP20170383T1 (en) 2017-05-05
US9365482B2 (en) 2016-06-14
EP2961727B1 (en) 2016-12-28
CN107673964B (en) 2021-03-23
PT2961727T (en) 2017-03-08
JP6325580B2 (en) 2018-05-16
EP2961727A2 (en) 2016-01-06
TW201500342A (en) 2015-01-01
CN105102414A (en) 2015-11-25
TWI624453B (en) 2018-05-21
HUE031763T2 (en) 2017-07-28
WO2014132135A2 (en) 2014-09-04
CN107673964A (en) 2018-02-09
JP2016508523A (en) 2016-03-22
KR102179351B1 (en) 2020-11-18
AU2014222390A1 (en) 2015-09-17
DK2961727T3 (en) 2017-03-13

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