WO2013138654A1 - Methods of administering high concentrations of nitric oxide - Google Patents
Methods of administering high concentrations of nitric oxide Download PDFInfo
- Publication number
- WO2013138654A1 WO2013138654A1 PCT/US2013/031665 US2013031665W WO2013138654A1 WO 2013138654 A1 WO2013138654 A1 WO 2013138654A1 US 2013031665 W US2013031665 W US 2013031665W WO 2013138654 A1 WO2013138654 A1 WO 2013138654A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- nitric oxide
- ppm
- concentration
- cylinder
- delivery
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
- A61M16/12—Preparation of respiratory gases or vapours by mixing different gases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/021—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes operated by electrical means
- A61M16/022—Control means therefor
- A61M16/024—Control means therefor including calculation means, e.g. using a processor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/06—Respiratory or anaesthetic masks
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/20—Valves specially adapted to medical respiratory devices
- A61M16/201—Controlled valves
- A61M16/202—Controlled valves electrically actuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
- A61M2016/0015—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
- A61M2016/0018—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
- A61M2016/0021—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical with a proportional output signal, e.g. from a thermistor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
- A61M2016/0027—Accessories therefor, e.g. sensors, vibrators, negative pressure pressure meter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
- A61M2016/003—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter
- A61M2016/0033—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical
- A61M2016/0039—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical in the inspiratory circuit
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/02—Gases
- A61M2202/0266—Nitrogen (N)
- A61M2202/0275—Nitric oxide [NO]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
- A61M2205/3334—Measuring or controlling the flow rate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/50—General characteristics of the apparatus with microprocessors or computers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/50—General characteristics of the apparatus with microprocessors or computers
- A61M2205/502—User interfaces, e.g. screens or keyboards
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Emergency Medicine (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
Claims
Priority Applications (16)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201380019833.6A CN104411317A (en) | 2012-03-15 | 2013-03-14 | Methods of administering high concentrations of nitric oxide |
EP13714771.6A EP2825179B1 (en) | 2012-03-15 | 2013-03-14 | Methods of administering high concentrations of nitric oxide |
DK13714771.6T DK2825179T3 (en) | 2012-03-15 | 2013-03-14 | METHODS OF ADMINISTRATION HIGH CONCENTRATIONS OF NITRIC OXIDE |
JP2015500634A JP6245613B2 (en) | 2012-03-15 | 2013-03-14 | Administration of high concentrations of nitric oxide |
CA2867022A CA2867022C (en) | 2012-03-15 | 2013-03-14 | Methods of administering high concentrations of nitric oxide |
ES13714771T ES2894962T3 (en) | 2012-03-15 | 2013-03-14 | Methods of administration of high concentrations of nitric oxide |
EP21190302.6A EP3970729A3 (en) | 2012-03-15 | 2013-03-14 | Methods of administering high concentrations of nitric oxide |
PL13714771T PL2825179T3 (en) | 2012-03-15 | 2013-03-14 | Methods of administering high concentrations of nitric oxide |
BR112014022627A BR112014022627A8 (en) | 2012-03-15 | 2013-03-14 | NITRIC OXIDE AND GAS RELEASE DEVICE COMPRISING NITRIC OXIDE |
AU2013231976A AU2013231976B9 (en) | 2012-03-15 | 2013-03-14 | Methods of administering high concentrations of nitric oxide |
MX2014011010A MX368858B (en) | 2012-03-15 | 2013-03-14 | Methods of administering high concentrations of nitric oxide. |
HK15106849.3A HK1206255A1 (en) | 2012-03-15 | 2015-07-17 | Methods of administering high concentrations of nitric oxide |
AU2017265011A AU2017265011B2 (en) | 2012-03-15 | 2017-11-21 | Methods of administering high concentrations of nitric oxide |
AU2020202487A AU2020202487B2 (en) | 2012-03-15 | 2020-04-13 | Methods of administering high concentrations of nitric oxide |
CY20211100967T CY1124713T1 (en) | 2012-03-15 | 2021-11-09 | METHODS OF ADMINISTERING HIGH CONCENTRATIONS OF NITRIC OXIDE |
AU2022241504A AU2022241504A1 (en) | 2012-03-15 | 2022-09-28 | Methods of administering high concentrations of nitric oxide |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13/420,852 | 2012-03-15 | ||
US13/420,852 US20130239962A1 (en) | 2012-03-15 | 2012-03-15 | Methods Of Administering High Concentrations Of Nitric Oxide |
US13/827,240 US10556086B2 (en) | 2012-03-15 | 2013-03-14 | Methods of administering high concentrations of nitric oxide |
US13/827,240 | 2013-03-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2013138654A1 true WO2013138654A1 (en) | 2013-09-19 |
Family
ID=48050277
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2013/031665 WO2013138654A1 (en) | 2012-03-15 | 2013-03-14 | Methods of administering high concentrations of nitric oxide |
Country Status (8)
Country | Link |
---|---|
US (3) | US10556086B2 (en) |
JP (3) | JP6245613B2 (en) |
CN (1) | CN104411317A (en) |
AU (4) | AU2013231976B9 (en) |
BR (1) | BR112014022627A8 (en) |
CA (1) | CA2867022C (en) |
MX (3) | MX368858B (en) |
WO (1) | WO2013138654A1 (en) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2867022C (en) * | 2012-03-15 | 2020-12-15 | Ino Therapeutics Llc | Methods of administering high concentrations of nitric oxide |
EP3020438A1 (en) * | 2014-11-13 | 2016-05-18 | Linde AG | Device for ventilating a patient and method for operating a device for ventilating a patient |
KR20180095504A (en) | 2015-10-01 | 2018-08-27 | 말린크로트 하스피탈 프로덕츠 아이피 리미티드 | Apparatus and method for diffusing high concentration NO by inhalation therapy gas |
MX2020010523A (en) | 2017-02-27 | 2021-02-09 | Third Pole Inc | Systems and methods for generating nitric oxide. |
WO2018157175A1 (en) | 2017-02-27 | 2018-08-30 | Third Pole, Inc. | Systems and methods for ambulatory generation of nitric oxide |
AU2018223826B2 (en) | 2017-02-27 | 2019-11-07 | Third Pole, Inc. | Systems and methods for generating nitric oxide |
US20200384014A1 (en) * | 2017-12-28 | 2020-12-10 | Bellerophon Pulse Technologies Llc | Pulsed Administration Of Inhaled Nitric Oxide For The Treatment Of Pulmonary Hypertension |
EP3793437A4 (en) * | 2018-05-17 | 2022-02-23 | Bellerophon Therapeutics | Method and apparatus for pulsatile delivery of nitric oxide |
EP3969415A4 (en) | 2019-05-15 | 2023-08-16 | Third Pole, Inc. | Electrodes for nitric oxide generation |
JP2022532654A (en) | 2019-05-15 | 2022-07-15 | サード ポール,インコーポレイテッド | Systems and methods for producing nitric oxide |
JP2023512444A (en) | 2020-01-11 | 2023-03-27 | サード ポール,インコーポレイテッド | Systems and methods for nitric oxide generation using humidity control |
WO2021258025A1 (en) | 2020-06-18 | 2021-12-23 | Third Pole, Inc. | Systems and methods for preventing and treating infections with nitric oxide |
CN112807543B (en) * | 2021-02-03 | 2022-08-02 | 西安交通大学医学院第二附属医院 | Pain therapeutic instrument with audio-visual and olfactory triple senses |
US11975139B2 (en) | 2021-09-23 | 2024-05-07 | Third Pole, Inc. | Systems and methods for delivering nitric oxide |
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US5823180A (en) * | 1995-04-03 | 1998-10-20 | The General Hospital Corporation | Methods for treating pulmonary vasoconstriction and asthma |
WO2008095312A1 (en) * | 2007-02-09 | 2008-08-14 | Pulmonox Technologies Corporation | Use of high dose concentrations of gaseous nitric oxide |
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-
2013
- 2013-03-14 CA CA2867022A patent/CA2867022C/en active Active
- 2013-03-14 BR BR112014022627A patent/BR112014022627A8/en not_active Application Discontinuation
- 2013-03-14 MX MX2014011010A patent/MX368858B/en active IP Right Grant
- 2013-03-14 AU AU2013231976A patent/AU2013231976B9/en active Active
- 2013-03-14 US US13/827,240 patent/US10556086B2/en active Active
- 2013-03-14 WO PCT/US2013/031665 patent/WO2013138654A1/en active Application Filing
- 2013-03-14 JP JP2015500634A patent/JP6245613B2/en active Active
- 2013-03-14 CN CN201380019833.6A patent/CN104411317A/en active Pending
-
2014
- 2014-09-12 MX MX2019004034A patent/MX2019004034A/en unknown
- 2014-09-12 MX MX2022008236A patent/MX2022008236A/en unknown
-
2017
- 2017-11-08 JP JP2017215161A patent/JP6466543B2/en active Active
- 2017-11-21 AU AU2017265011A patent/AU2017265011B2/en active Active
-
2019
- 2019-01-09 JP JP2019001785A patent/JP6807409B2/en active Active
-
2020
- 2020-02-10 US US16/785,983 patent/US11660416B2/en active Active
- 2020-04-13 AU AU2020202487A patent/AU2020202487B2/en active Active
-
2022
- 2022-09-28 AU AU2022241504A patent/AU2022241504A1/en active Pending
-
2023
- 2023-04-19 US US18/136,522 patent/US20230256190A1/en active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5823180A (en) * | 1995-04-03 | 1998-10-20 | The General Hospital Corporation | Methods for treating pulmonary vasoconstriction and asthma |
WO2008095312A1 (en) * | 2007-02-09 | 2008-08-14 | Pulmonox Technologies Corporation | Use of high dose concentrations of gaseous nitric oxide |
Non-Patent Citations (2)
Title |
---|
KRASUSKI ET AL: "The response to inhaled nitric oxide in patients with pulmonary artery hypertension is not masked by baseline vasodilator use", AMERICAN HEART JOURNAL, MOSBY- YEAR BOOK INC, US, vol. 150, no. 4, 1 October 2005 (2005-10-01), pages 725 - 728, XP005094571, ISSN: 0002-8703, DOI: 10.1016/J.AHJ.2004.10.012 * |
ROBERTS J D JR ET AL: "Inhaled nitric oxide and persistent pulmonary hypertension of the newborn. The Inhaled Nitric Oxide Study Group", NEW ENGLAND JOURNAL OF MEDICINE, THE, MASSACHUSETTS MEDICAL SOCIETY, WALTHAM, MA, US, vol. 336, no. 9, 27 February 1997 (1997-02-27), pages 605 - 610, XP009169309, ISSN: 0028-4793 * |
Also Published As
Publication number | Publication date |
---|---|
MX2014011010A (en) | 2014-10-13 |
AU2017265011B2 (en) | 2020-01-23 |
JP2018070616A (en) | 2018-05-10 |
MX2022008236A (en) | 2022-07-19 |
CA2867022A1 (en) | 2013-09-19 |
JP6245613B2 (en) | 2017-12-13 |
JP2015517983A (en) | 2015-06-25 |
MX2019004034A (en) | 2019-07-04 |
US11660416B2 (en) | 2023-05-30 |
JP6807409B2 (en) | 2021-01-06 |
JP2019089775A (en) | 2019-06-13 |
AU2020202487B2 (en) | 2022-06-30 |
AU2022241504A1 (en) | 2022-10-27 |
BR112014022627A8 (en) | 2021-10-19 |
AU2013231976A1 (en) | 2014-10-09 |
JP6466543B2 (en) | 2019-02-06 |
AU2013231976B2 (en) | 2017-12-07 |
US20230256190A1 (en) | 2023-08-17 |
US20200171264A1 (en) | 2020-06-04 |
BR112014022627A2 (en) | 2017-06-20 |
CN104411317A (en) | 2015-03-11 |
US10556086B2 (en) | 2020-02-11 |
AU2013231976B9 (en) | 2017-12-14 |
AU2017265011A1 (en) | 2018-01-04 |
MX368858B (en) | 2019-10-18 |
CA2867022C (en) | 2020-12-15 |
US20130239963A1 (en) | 2013-09-19 |
AU2020202487A1 (en) | 2020-05-21 |
AU2013231976A2 (en) | 2014-10-23 |
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