WO2013124820A1 - Composition comprising a retinoid and benzoyl peroxide - Google Patents
Composition comprising a retinoid and benzoyl peroxide Download PDFInfo
- Publication number
- WO2013124820A1 WO2013124820A1 PCT/IB2013/051434 IB2013051434W WO2013124820A1 WO 2013124820 A1 WO2013124820 A1 WO 2013124820A1 IB 2013051434 W IB2013051434 W IB 2013051434W WO 2013124820 A1 WO2013124820 A1 WO 2013124820A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- composition
- benzoyl peroxide
- adapalene
- stable topical
- aqueous composition
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/327—Peroxy compounds, e.g. hydroperoxides, peroxides, peroxyacids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/042—Gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/046—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/38—Percompounds, e.g. peracids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/731—Cellulose; Quaternized cellulose derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/48—Thickener, Thickening system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Birds (AREA)
- Dermatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- Emergency Medicine (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
Abstract
Description
Claims
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN7896DEN2014 IN2014DN07896A (en) | 2012-02-21 | 2013-02-21 | |
EP13717315.9A EP2817069A1 (en) | 2012-02-21 | 2013-02-21 | Composition comprising a retinoid and benzoyl peroxide |
BR112014020545A BR112014020545A2 (en) | 2012-02-21 | 2013-02-21 | stable topical aqueous composition, process for preparing the stable topical aqueous composition and method for treating acne |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN497/DEL/2012 | 2012-02-21 | ||
IN497DE2012 IN2012DE00497A (en) | 2012-02-21 | 2013-02-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2013124820A1 true WO2013124820A1 (en) | 2013-08-29 |
Family
ID=48142029
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IB2013/051434 WO2013124820A1 (en) | 2012-02-21 | 2013-02-21 | Composition comprising a retinoid and benzoyl peroxide |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP2817069A1 (en) |
BR (1) | BR112014020545A2 (en) |
IN (2) | IN2014DN07896A (en) |
WO (1) | WO2013124820A1 (en) |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2018073751A1 (en) * | 2016-10-17 | 2018-04-26 | Sun Pharmaceutical Industries Limited | Method of treating acne |
US10959933B1 (en) | 2020-06-01 | 2021-03-30 | The Procter & Gamble Company | Low pH skin care composition and methods of using the same |
EP3723748A4 (en) * | 2017-12-15 | 2021-07-21 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | The combination comprising adapalene, benzoyl peroxide and an agent from the cicatrizant group |
US11110049B2 (en) | 2017-06-23 | 2021-09-07 | The Procter & Gamble Company | Composition and method for improving the appearance of skin |
EP3723747A4 (en) * | 2017-12-15 | 2021-11-03 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | The combination comprising adapalene and benzoyl peroxide |
US11583488B2 (en) | 2020-06-01 | 2023-02-21 | The Procter & Gamble Company | Method of improving penetration of a vitamin B3 compound into skin |
US11622963B2 (en) | 2018-07-03 | 2023-04-11 | The Procter & Gamble Company | Method of treating a skin condition |
Citations (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4350681A (en) | 1977-10-07 | 1982-09-21 | A.H.C. Pharmacal, Inc. | Stabilized benzoyl peroxide compositions |
US4361584A (en) | 1977-10-07 | 1982-11-30 | A.H.C. Pharmacal, Inc. | Composition and method for the treatment of acne |
US4387107A (en) | 1979-07-25 | 1983-06-07 | Dermik Laboratories, Inc. | Stable benzoyl peroxide composition |
US4497794A (en) | 1980-12-08 | 1985-02-05 | Dermik Laboratories, Inc. | Erythromycin/benzoyl peroxide composition for the treatment of acne |
US4671956A (en) | 1983-12-01 | 1987-06-09 | L'oreal | Antiacne composition containing benzoic peroxide in association with at least one sun filter |
US4960772A (en) | 1988-03-09 | 1990-10-02 | L'oreal | Benzoyl peroxide and quaternary ammonium based pharmaceutical and cosmetic compositions |
US5086075A (en) | 1985-01-24 | 1992-02-04 | Board Of Regents, The University Of Texas System | Therapeutic compositions containing benzoyl peroxide |
US5145675A (en) | 1986-03-31 | 1992-09-08 | Advanced Polymer Systems, Inc. | Two step method for preparation of controlled release formulations |
US5466446A (en) | 1994-02-16 | 1995-11-14 | Stiefel Laboratories, Inc. | Topical compositions containing bensoyl peroxide and clindamycin and method of use thereof |
US5632996A (en) | 1995-04-14 | 1997-05-27 | Imaginative Research Associates, Inc. | Benzoyl peroxide and benzoate ester containing compositions suitable for contact with skin |
US5767098A (en) | 1985-12-12 | 1998-06-16 | Dermik Laboratories, Inc. | Anti-acne method and composition |
US5851538A (en) | 1995-12-29 | 1998-12-22 | Advanced Polymer Systems, Inc. | Retinoid formulations in porous microspheres for reduced irritation and enhanced stability |
US5879716A (en) | 1985-12-18 | 1999-03-09 | Advanced Polymer Systems, Inc. | Methods and compositions for topical delivery of benzoyl peroxide |
US5955109A (en) | 1985-12-18 | 1999-09-21 | Advanced Polymer Systems, Inc. | Methods and compositions for topical delivery of retinoic acid |
US5998392A (en) | 1996-04-10 | 1999-12-07 | Gattefosse S.A. | Benzoyl peroxide flocculent materials and methods of their preparation |
US6013637A (en) | 1998-06-12 | 2000-01-11 | Dermik Laboratories Inc. | Anti-acne method and composition |
US6117843A (en) | 1992-02-18 | 2000-09-12 | Lloyd J. Baroody | Compositions for the treatment of acne containing clindamycin and benzoyl peroxide |
US20020064541A1 (en) | 2000-04-21 | 2002-05-30 | Noa Lapidot | Composition exhibiting enhanced formulation stability and delivery of topical active ingredients |
US20030170196A1 (en) | 2001-12-21 | 2003-09-11 | Sandrine Orsoni | Dermatological/cosmetic gels comprising at least one retinoid and benzoyl peroxide |
US20050037087A1 (en) | 2001-11-08 | 2005-02-17 | Noa Lapidot | Compositions containing oils having a specific gravity higher than the specific gravity of water |
WO2008017914A2 (en) * | 2006-08-08 | 2008-02-14 | Fernando Ahumada Ayala | Topical antiacne preparations containing retinoid (tazarotene or adapalene), antibiotic (clindamycin phosphate) and/or keratolytic (miscrosponged benzoyl peroxide) |
WO2008107193A1 (en) * | 2007-03-06 | 2008-09-12 | Almirall Hermal Gmbh | Topical composition comprising retinoid receptor agonist for treatment of acne |
US20090318550A1 (en) | 2006-12-21 | 2009-12-24 | Galderma Research & Development | Emulsions comprising at least one retinoid and benzoyl peroxide |
US20100022642A1 (en) | 2006-07-13 | 2010-01-28 | Galderma Research & Development | Dermatological/cosmetic compositions comprising a retinoid and benzoyl peroxide |
US20100143285A1 (en) | 2006-11-28 | 2010-06-10 | Galderma Research & Development, Biot, France. | Dermatological/pharmaceutical compositions comprising benzoyl peroxide, at least one naphthoic acid compound and at least one polyurethane polymer |
US20100166852A1 (en) | 2006-12-21 | 2010-07-01 | Galderma Research & Development | Cream gels comprising at least one retinoid and benzoyl peroxide |
US20110003894A1 (en) | 2008-01-10 | 2011-01-06 | Galderma Research & Development | Dermatological compositions comprising retinoids, dispersed benzoyl peroxide and carrageenans |
-
2013
- 2013-02-21 WO PCT/IB2013/051434 patent/WO2013124820A1/en active Application Filing
- 2013-02-21 EP EP13717315.9A patent/EP2817069A1/en not_active Withdrawn
- 2013-02-21 IN IN7896DEN2014 patent/IN2014DN07896A/en unknown
- 2013-02-21 IN IN497DE2012 patent/IN2012DE00497A/en unknown
- 2013-02-21 BR BR112014020545A patent/BR112014020545A2/en not_active IP Right Cessation
Patent Citations (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4350681A (en) | 1977-10-07 | 1982-09-21 | A.H.C. Pharmacal, Inc. | Stabilized benzoyl peroxide compositions |
US4361584A (en) | 1977-10-07 | 1982-11-30 | A.H.C. Pharmacal, Inc. | Composition and method for the treatment of acne |
US4387107A (en) | 1979-07-25 | 1983-06-07 | Dermik Laboratories, Inc. | Stable benzoyl peroxide composition |
US4497794A (en) | 1980-12-08 | 1985-02-05 | Dermik Laboratories, Inc. | Erythromycin/benzoyl peroxide composition for the treatment of acne |
US4671956A (en) | 1983-12-01 | 1987-06-09 | L'oreal | Antiacne composition containing benzoic peroxide in association with at least one sun filter |
US5086075A (en) | 1985-01-24 | 1992-02-04 | Board Of Regents, The University Of Texas System | Therapeutic compositions containing benzoyl peroxide |
US5767098A (en) | 1985-12-12 | 1998-06-16 | Dermik Laboratories, Inc. | Anti-acne method and composition |
US5879716A (en) | 1985-12-18 | 1999-03-09 | Advanced Polymer Systems, Inc. | Methods and compositions for topical delivery of benzoyl peroxide |
US5955109A (en) | 1985-12-18 | 1999-09-21 | Advanced Polymer Systems, Inc. | Methods and compositions for topical delivery of retinoic acid |
US5145675A (en) | 1986-03-31 | 1992-09-08 | Advanced Polymer Systems, Inc. | Two step method for preparation of controlled release formulations |
US4960772A (en) | 1988-03-09 | 1990-10-02 | L'oreal | Benzoyl peroxide and quaternary ammonium based pharmaceutical and cosmetic compositions |
US6117843A (en) | 1992-02-18 | 2000-09-12 | Lloyd J. Baroody | Compositions for the treatment of acne containing clindamycin and benzoyl peroxide |
US5466446A (en) | 1994-02-16 | 1995-11-14 | Stiefel Laboratories, Inc. | Topical compositions containing bensoyl peroxide and clindamycin and method of use thereof |
US5632996A (en) | 1995-04-14 | 1997-05-27 | Imaginative Research Associates, Inc. | Benzoyl peroxide and benzoate ester containing compositions suitable for contact with skin |
US5851538A (en) | 1995-12-29 | 1998-12-22 | Advanced Polymer Systems, Inc. | Retinoid formulations in porous microspheres for reduced irritation and enhanced stability |
US5998392A (en) | 1996-04-10 | 1999-12-07 | Gattefosse S.A. | Benzoyl peroxide flocculent materials and methods of their preparation |
US6013637A (en) | 1998-06-12 | 2000-01-11 | Dermik Laboratories Inc. | Anti-acne method and composition |
US20020064541A1 (en) | 2000-04-21 | 2002-05-30 | Noa Lapidot | Composition exhibiting enhanced formulation stability and delivery of topical active ingredients |
US20050037087A1 (en) | 2001-11-08 | 2005-02-17 | Noa Lapidot | Compositions containing oils having a specific gravity higher than the specific gravity of water |
US7820186B2 (en) | 2001-12-21 | 2010-10-26 | Galderma Research & Development | Gel composition for once-daily treatment of common acne comprising a combination of benzoyl peroxide and adapalene and/or adapalene salt |
US20030170196A1 (en) | 2001-12-21 | 2003-09-11 | Sandrine Orsoni | Dermatological/cosmetic gels comprising at least one retinoid and benzoyl peroxide |
US20080176954A1 (en) | 2001-12-21 | 2008-07-24 | Galderma Research & Development, S.N.C. | Dermatological/cosmetic gels comprising at least one retinoid and benzoyl peroxide |
US7964202B2 (en) | 2001-12-21 | 2011-06-21 | Galderma Research & Development, S.N.C. | Method for treatment of common acne |
US20110070274A1 (en) | 2001-12-21 | 2011-03-24 | Galderma Research & Development | Dermatological/cosmetic gels comprising at least one retinoid and benzoyl peroxide |
US20100022642A1 (en) | 2006-07-13 | 2010-01-28 | Galderma Research & Development | Dermatological/cosmetic compositions comprising a retinoid and benzoyl peroxide |
WO2008017914A2 (en) * | 2006-08-08 | 2008-02-14 | Fernando Ahumada Ayala | Topical antiacne preparations containing retinoid (tazarotene or adapalene), antibiotic (clindamycin phosphate) and/or keratolytic (miscrosponged benzoyl peroxide) |
US20100143285A1 (en) | 2006-11-28 | 2010-06-10 | Galderma Research & Development, Biot, France. | Dermatological/pharmaceutical compositions comprising benzoyl peroxide, at least one naphthoic acid compound and at least one polyurethane polymer |
US20100166852A1 (en) | 2006-12-21 | 2010-07-01 | Galderma Research & Development | Cream gels comprising at least one retinoid and benzoyl peroxide |
US20090318550A1 (en) | 2006-12-21 | 2009-12-24 | Galderma Research & Development | Emulsions comprising at least one retinoid and benzoyl peroxide |
WO2008107193A1 (en) * | 2007-03-06 | 2008-09-12 | Almirall Hermal Gmbh | Topical composition comprising retinoid receptor agonist for treatment of acne |
US20110003894A1 (en) | 2008-01-10 | 2011-01-06 | Galderma Research & Development | Dermatological compositions comprising retinoids, dispersed benzoyl peroxide and carrageenans |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2018073751A1 (en) * | 2016-10-17 | 2018-04-26 | Sun Pharmaceutical Industries Limited | Method of treating acne |
US11110049B2 (en) | 2017-06-23 | 2021-09-07 | The Procter & Gamble Company | Composition and method for improving the appearance of skin |
EP3723748A4 (en) * | 2017-12-15 | 2021-07-21 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | The combination comprising adapalene, benzoyl peroxide and an agent from the cicatrizant group |
EP3723747A4 (en) * | 2017-12-15 | 2021-11-03 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | The combination comprising adapalene and benzoyl peroxide |
US11622963B2 (en) | 2018-07-03 | 2023-04-11 | The Procter & Gamble Company | Method of treating a skin condition |
US10959933B1 (en) | 2020-06-01 | 2021-03-30 | The Procter & Gamble Company | Low pH skin care composition and methods of using the same |
US11583488B2 (en) | 2020-06-01 | 2023-02-21 | The Procter & Gamble Company | Method of improving penetration of a vitamin B3 compound into skin |
US11911498B2 (en) | 2020-06-01 | 2024-02-27 | The Procter & Gamble Company | Low pH skin care composition and methods of using the same |
Also Published As
Publication number | Publication date |
---|---|
EP2817069A1 (en) | 2014-12-31 |
IN2012DE00497A (en) | 2015-06-05 |
IN2014DN07896A (en) | 2015-04-24 |
BR112014020545A2 (en) | 2019-09-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2013124820A1 (en) | Composition comprising a retinoid and benzoyl peroxide | |
JP5622582B2 (en) | Composition comprising at least one naphthoic acid derivative, benzoyl peroxide and at least one film former, method for its preparation and use thereof | |
CN1329025C (en) | Dermatological/cosmetic gels comprising at least one retinoid and benzoyl peroxide | |
KR101500767B1 (en) | Cream-gel comprising at least one retinoid and benzoyl peroxide | |
DK2450035T3 (en) | Combination of adapalene and benzoyl peroxide for the treatment of acne lesions | |
CA2656451C (en) | Composition comprising a retinoid and benzoyl peroxide | |
US20170000758A1 (en) | Gel composition for treatment of common acne comprising a combination of benzoyl peroxide and adapalene and/or adapalene salt | |
JP2010513427A (en) | Emulsion comprising at least one retinoid and benzoyl peroxide | |
US20100029765A1 (en) | Topical aqueous composition comprising tretinoin | |
US8563535B2 (en) | Combination composition comprising benzoyl peroxide and adapalene | |
EP3723747B1 (en) | The combination comprising adapalene and benzoyl peroxide | |
US9060948B2 (en) | Dermatological/cosmetic compositions comprising a retinoid and benzoyl peroxide | |
WO2019190435A2 (en) | The combination comprising adapalene, benzoyl peroxide and an agent from the cicatrizant group | |
US20170095434A1 (en) | Combination of adapalene and benzoyl peroxide for the treatment of severe acne |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 13717315 Country of ref document: EP Kind code of ref document: A1 |
|
NENP | Non-entry into the national phase |
Ref country code: DE |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2013717315 Country of ref document: EP |
|
REG | Reference to national code |
Ref country code: BR Ref legal event code: B01A Ref document number: 112014020545 Country of ref document: BR |
|
ENP | Entry into the national phase |
Ref document number: 112014020545 Country of ref document: BR Kind code of ref document: A2 Effective date: 20140821 |