WO2013048000A2 - Porous cage for intervertebral fusion, and method for manufacturing same - Google Patents

Porous cage for intervertebral fusion, and method for manufacturing same Download PDF

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Publication number
WO2013048000A2
WO2013048000A2 PCT/KR2012/006304 KR2012006304W WO2013048000A2 WO 2013048000 A2 WO2013048000 A2 WO 2013048000A2 KR 2012006304 W KR2012006304 W KR 2012006304W WO 2013048000 A2 WO2013048000 A2 WO 2013048000A2
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WO
WIPO (PCT)
Prior art keywords
cage
porous
structure
fusion
insert
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Application number
PCT/KR2012/006304
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French (fr)
Korean (ko)
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WO2013048000A3 (en
Inventor
선두훈
김정성
김용화
조유정
이광훈
이종서
Original Assignee
주식회사 코렌텍
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Priority to KR10-2011-0098215 priority Critical
Priority to KR1020110098215A priority patent/KR101225006B1/en
Application filed by 주식회사 코렌텍 filed Critical 주식회사 코렌텍
Publication of WO2013048000A2 publication Critical patent/WO2013048000A2/en
Publication of WO2013048000A3 publication Critical patent/WO2013048000A3/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/146Porous materials, e.g. foams or sponges
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/4455Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages
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    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
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    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/4455Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages
    • A61F2/447Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages substantially parallelepipedal, e.g. having a rectangular or trapezoidal cross-section
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    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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    • A61F2002/30011The prosthesis made from materials having different values of a given property at different locations within the same prosthesis differing in porosity
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    • A61F2/30771Special external or bone-contacting surfaces, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/3082Grooves
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    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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    • A61F2/30771Special external or bone-contacting surfaces, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/3082Grooves
    • A61F2002/30827Plurality of grooves
    • A61F2002/30828Plurality of grooves parallel
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    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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    • A61F2002/3092Special external or bone-contacting surfaces, e.g. coating for improving bone ingrowth having an open-celled or open-pored structure
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    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
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    • A61F2/3094Designing or manufacturing processes
    • A61F2002/30968Sintering
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Abstract

The present invention relates to a cage to be inserted between adjacent vertebrae and to be used for vertebral fusion, and to a method for manufacturing same, and more particularly, to an intervertebral fusion porous cage and to a method for manufacturing same, wherein the cage includes: a nonporous insert; and a porous structure enclosing the exterior of the insert, wherein the insert includes a connecting portion connected to a surgical instrument used for manipulating the cage, and an extending portion projecting from the top surface of the connecting portion and extending a certain distance in the lengthwise direction of the cage, and the structure is formed so as to contact the top surface of the connecting portion and the outer surface of the extending portion, and is porous and the strength thereof is reinforced.

Description

Porous cage for fusion between the vertebral bodies and a method of manufacturing the same

The present invention is inserted between the vertebral bodies adjacent that of the cage, and a manufacturing method used for vertebral fusion, and more particularly, to a non-porous insert, and; Porosity of the structure surrounding the outer surface of the insert; wherein the said insert is extended to protrude from the upper surface of the connection portion and the connection portion that is connected to the surgical instrument that is used for the operation of the cage extending in a predetermined length in the longitudinal direction of the cage include a, and the structure is for the top and bottom surfaces are formed so as to extend in contact with the outer surface portion, a porous cage for fusion between the vertebral bodies while having a porosity at the same time reinforcing the strength, and a manufacturing method of the connection.

Vertebral bodies of the vertebrae 32-35 are intervertebral disc (intervertebral disk) between (vertebra) and vertebrae form a body that is composed of a disc, the hub of the body to the holding yirumyeonseo of trunk connection to the top of the skull with the lower end of the pelvic It forms a part. Vertebrae is through interaction seven cervical (cervical), 12 of thoracic (thoracic), five lumbar (lumber), five sacral (sacrum), 3~5 of Mitsu (coccyx) from above, adults are five sacral fused to become one sacrum, the 3-5 caudal is a fusion with one caudal.

When the disc is ruptured or weakened due to illness or accident to the pain caused by pressure on the spinal cord, insert this case artificial correction chain cage to remove the damaged disk and restore and maintain the spacing of the two vertebrae between adjacent vertebrae the effect on the fusion between the vertebrae. It is important to increase the In bone engagement with the implanted cage and vertebrae (bone integration) for the fusion, and the design is put bone empty space therein so as to grow for this purpose, and autogenous bone (autograft) in order to promote the growth of bone , and an attempt to promote bone fusion, such as filling the allograft (allograft), or synthetic bone (synthetic bone) in the empty space. Recently, to shorten the time to so that the bone tissue penetration (bone ingrowth) up to the macropores (macropore) present in the cage when implanted in the body to produce a porous cage as a cage fixed and the clamping force required is increased.

However, bone, etc., and the cost-effectiveness issues that are so large if you use a cage filled on the inside, if you are using a porous cage is fused with the surrounding bone tissue easily one falls, the strength to support the vertebrae, the cage conventional method for producing a porous so that it will be using the expensive equipment, and is longer the time, the manufacturing process increases the manufacturing costs, the pore precursor, such as a binder or with toxicity, even after producing a porous cage, there is the problem left in the cage.

The present invention has been made to solve the above problems,

The present invention is inserted between the vertebral bodies adjacent there is provided a porous cross-vertebral cage and a manufacturing method for the fusion, which is used to vertebral fusion.

In addition, the invention provides a vertebral body between the porous cage and a manufacturing method for the fusion, at the same time while having a porous reinforcing the strength by the combination of the structure of the porous and non-porous insert has the purpose.

The invention also vertebral body between the fusion capable of including embedded grooves are embedded at a predetermined depth is formed along the outer side, by increasing the area of ​​contact with the extension part of the structure rigidly coupled to the structure to the insert to provide a porous cage for and a method of manufacturing it is an object.

In addition, the present invention does not use any such pore precursor or binder, in the manufacture and harmless to the human body, and can be produced in a short time at a low temperature by using the electric current sintering apparatus porous for inter-vertebral body that can reduce the production cost fusion to provide a cage and a method of manufacturing it is an object.

The invention is implemented by the embodiment has the following configuration to achieve the above object the present.

According to one embodiment of the invention, a porous cage for fusion between the vertebral bodies in accordance with the present invention and a non-porous insert; Porosity of the structure surrounding the outer surface of the insert; includes, the insert and the connection that is connected to the surgical instrument that is used for the operation of the cage, it is projected in an upper surface of the connecting portion and extending a predetermined length in the longitudinal direction of the cage including an extended portion, and wherein the structure is formed so as to contact the outer surface of the upper surface and extending portions of the connecting portion, while having a porous structure at the same time by the above is characterized in that the strength is reinforced by the insert.

In accordance with another embodiment of the present invention, there is provided a porous cage between vertebral fusion of the present invention, including the embedded groove formed along the outer side of the extension portion is embedded to a predetermined depth, and contacts with the extension part of the structure by increasing the surface area it is characterized in that it can be rigidly coupled to the structure to the insert.

According to a further embodiment of the present invention, in the structure in a porous cage for fusion between the vertebral body according to the invention it is characterized by having a porosity of 10 to 80%.

According to a further embodiment of the present invention, there is provided a porous cage between vertebral fusion of the present invention the connecting part is embedded in when being formed, including a coupling groove that surgical instruments used for the operation of the cage to be inserted and that is characterized.

According to a further embodiment of the present invention, the length of the porous structure in the cage between the vertebral fusion of the present invention is characterized in that it has a greater than 1 to 70% longer length of the length of the extension portion,

According to a further embodiment of the present invention, the length of the porous structure in the cage between the vertebral fusion of the present invention is characterized in that it has a greater than 1 to 20% longer length of the length of the extension portion.

According to a further embodiment of the present invention, in the structure in a porous cage between vertebral fusion according to the invention, and filling the insert and the material in the mold, it is filled in the mold by using the electric current sintering device outside of the insert applying a predetermined pressure at the same time, the material which is located by passing the raw material is being prepared by sintering the material at a constant temperature.

According to a further embodiment of the present invention, there is provided a porous cage for fusion between the vertebral body according to the invention and the pressure is from 100 to 2000㎏f / ㎠, the temperature is from 800 to 1400 ℃, 500 for energizing the raw material to characterized in that applying a voltage of 3 to 7V and a current of 2000A.

According to a further embodiment of the present invention, the raw material in a porous cage between vertebral fusion of the present invention is a metal powder or ceramic powder, the metal is titanium, titanium alloy, cobalt chromium, cobalt chromium alloys, tantalum, tantalum alloy, niobium, and at least one selected from the group consisting of niobium alloys and titanium nitride, the ceramic is characterized in that at least one selected from the group consisting of tricalcium phosphate, calcium hydroxyapatite, zirconia and alumina.

The invention by the above configuration and the bond, using the relationship to be described in the present embodiment, the following effects can be obtained.

The present invention is inserted between the vertebral bodies which are adjacent has the effect that can be used for vertebral fusion.

Further, the present invention may have a while having a porous structure by the combination of the porous and non-porous insert at the same time, the strength reinforcing effect.

In addition, the present invention has an effect capable of including embedded grooves are embedded at a predetermined depth is formed along the outer side, by increasing the area of ​​contact with the extension part of the structure rigidly coupled to the structure to the insert .

The invention also has the effect of shortening the manufacturing does not use any such pore precursor or binder, in the manufacture and harmless to the human body, can be produced in a short time at a low temperature by using the electric current sintering equipment cost.

1 is a perspective view of a porous cage for fusion between the vertebral bodies, according to one embodiment of the present invention.

2 is a cross-sectional view of a porous cage for fusion between the vertebral bodies, according to one embodiment of the present invention.

3 is a perspective view of an insert for use in a porous cage for fusion between the vertebral bodies, according to one embodiment of the present invention.

4 is a photograph of a porous cage for fusion between the vertebral bodies, according to one embodiment of the present invention.

5 is a SEM picture of a porous cage for fusion between the vertebral bodies, according to one embodiment of the present invention.

6 is a schematic diagram of electric current sintering device used in the method of manufacturing a porous cage for fusion between the vertebral bodies, according to one embodiment of the present invention.

Figure 7 is a flow chart showing a manufacturing method of a porous cage for fusion between the vertebral bodies, according to one embodiment of the present invention.

* Description of Reference Numerals used in the drawings

1: cage 11: insert 12: structure

111: connecting portion 112: extending portion 111a: projection

111b: engaging groove 112a: Home constriction

Hereinafter, with reference to the accompanying drawings, a porous cage, and a manufacturing method for fusion between the vertebral bodies of the present invention will be described in detail. If all terms in the specification is in conflict with the meaning of terms used in the same, and if the specification and general sense of the word is to understand a technician skilled in the art, the definitions used in this specification to comply with.

Figure 1 is a perspective view of a porous cage between vertebral fusion in accordance with one embodiment of the present invention, Figure 2 is a cross-sectional view of a porous cage between vertebral fusion in accordance with one embodiment of the present invention, Figure 3 is one embodiment of the present invention a perspective view of an insert for use in a porous cage between vertebral fusion, according to the example, Fig. 4 is a photograph of a porous cage between vertebral fusion in accordance with one embodiment of the invention, Figure 5 is vertebral body according to one embodiment of the present invention a SEM image of a porous cage for fusion between.

Referring to Figure 1-5, and a porous cage (1) are inserts (11) of non-porous for fusion between the vertebral bodies, according to one embodiment of the present invention; Porosity of the structure 12 surrounding the outer surface of the insert 11; including, while having a porosity by the structure 12 at the same time is characterized in that the strength is reinforced by the insert 11.

The insert 11 is configured to bond with the surgical instrument for treatment of the cage (1) and the reinforcement cage (1) the strength of the exterior surface is surrounded by the porous structure 12. The insert 11 is so configured to be located inside the structure 12 of the porous reinforcing the strength of the cage (1), it has a dense texture of the non-porous. The insert 11 may be the same as a conventional non-porous implant, or is made of a similar material, it has a strength and a porosity equivalent to a conventional non-porous implants. The insert 11 preferably has a porosity of less than 1%. And said insert (11) comprises a structure such as a connecting portion 111, the extension 112.

The connecting portion 111 has a shape of rectangular as a gajina, predetermined shape configuration is connected to the surgical instrument that is used for treatment of the cage (1) is preferred. Both ends of a lower surface of the connection portion 111 has a projecting portion (111a) of the parallel protrusion pairs are formed the cage (1) and, and to maintain a coupling of the surgical instrument, is near the center of the lower surface of the connection portion 111 coupling groove (111b) portions thereof are inserted into the surgical instrument is formed makes it possible to facilitate the coupling of said cage (1) and the surgical instrument.

The extension portion 112 is coupled the outer side of the porous structure 12 of the connecting portion configured to protrude from the upper surface (111) extending a predetermined length in the longitudinal direction of the cage (1), the extended portion 112 do. The structure 12 is so porous that the strength of the relatively weak ve bound by, the extension in the interior of the structure 12, portion 112 is located, so it is possible to reinforce the strength of the cage (1). The cage (1) is increasingly a predetermined shape by gajina preferably end preferably has a conical shape of which the diameter decreases. The extension portion 112 includes a structure such as embedded grooves (112a).

The constriction grooves (112a) has a configuration that is embedded at a predetermined depth is formed along the outer surface of the extension part 112, by increasing the bonding surface area of ​​the structure 12 and the extension portion 112, the structure 12 It makes it possible to firmly bond to the said extension part (112). Referring to Figure 3, the constriction grooves (112a) is formed over the outer surface of all of the extended portion 112 has a V-shape, which is different for achieving the object of the constriction grooves (112a) that only illustrate one has a shape may be formed in a portion of the outer surface.

The structure 12 is a structure having a porous surrounds the outer surface of the insert 11, the outer surface of the treatment when the structure 12 of the cage (1) has pores of the structure 12 in contact with the vertebrae, the the bone tissue is penetrated. The structure 12 preferably has a porosity of 10 to 80% to facilitate penetration of bone tissue therein while having a constant intensity. Length (h2 of the cage (1), so as to have a porosity at the same time the strength reinforcing the structure 12 has the extended portion outer surface and the structure 12 abuts on the upper surface of the connection portion 111 of the 112, hereinafter defined as perpendicular to the structure 12 the length of the distance to the upper surface structure 12 in the upper surface of the connecting portion 111) are vertically from the top surface of the (length (h1, connection portion (111 of 112)), the extended portion length (h2) of the extension (112) defined hereinafter) that the length of the extension portion 112, the distance to the tip and greater than 1 to 70% longer desirable for the structure 12 has the extended portion 112 it is from 1 to 20% longer than that (h1) is further preferred.

Figures 1 to 2, the outer surface of the connecting portion 111 is formed so as not to the structure 12 where the structure 12 has outer dimensions of the whole gajina the form of a rectangular parallelepiped, which is outside of the connecting portion 111, that only illustrate one even side can be formed in the structure 12 so as to position the structure can have a variety of appearances. The structure 12 is composed of a metal or a ceramic material, wherein the metal is titanium (Titanium), titanium alloy (Titanium alloy), a cobalt chromium (Cobalt chromium), cobalt-chrome alloy (Cobalt chromium alloy), tantalum (Tantalum), tantalum alloy (tantalum alloy), niobium (niobium), niobium alloys (niobium alloy) and the nitride titanium (titanium nitride) and in which at least one metal selected from the group can be made of the ceramic is tricalcium phosphate ( Tricalcium phosphate), it may be any one or more ceramics selected from the group consisting of hydroxyapatite used (hydroxyapatite), zirconia (zirconia) and alumina (alumina).

The present invention can be rigidly coupled to the constriction grooves (112a), the extended portion 112 is formed to increase the bonding surface area of ​​the structure 12 and the insert 11 the structure 12 in the insert 11, and , because the extended part 112 having a high strength of the inner structure 12, where the cage (1) is characterized in that while maintaining the porosity can reinforce the strength.

6 is a schematic diagram of electric current sintering device used in the method of manufacturing a porous cage according to one embodiment of the invention, Figure 7 is a flow chart showing a manufacturing method of a porous cage according to one embodiment of the present invention.

Hereinafter, first, after explaining an electric current sintering device (2) for use in preparing the cage (1) according to one embodiment of the present invention will be described with reference to Figure 6, by using the electric current sintering device 2, the cage (1) a will be described how to manufacture.

The electric current sintering device (2) apply a pressure to the raw material 3 made of a powder inserted in the directly communicated electricity at a constant temperature in the device to make the product by sintering the raw material (3), the cavity casing 21 includes a structure such as a die 22, punch 23, the pressing means 24, a power supply 25, a control unit (not shown).

The casing 21 accommodates the die 22 and the punch 23 therein to form the outer shape of the electric current sintering apparatus 2 inside the manufacture products is maintained in a vacuum state.

The mold 22 is configured to receive the material (3) such as a metal powder or a ceramic powder as a raw material of the product, and inserted into the interior of the casing 21. The mold 22 is installed up and down comprises a through-hollow (221), each punch (23) has top and bottom of the hollow 221 so as to be movable up and down. The raw material 3 is to be won by modifying the shape of the hollow (221) and located in the space (S) formed by the punch 23 doemeuro product is produced, the hollow (221) and the punch (23) It can be manufactured in various shapes of products. The mold 22 is formed of a heat resistant material such as graphite through the electrical, and tungsten oxide, tungsten.

The punch 23 is respectively provided so as to be movable up and down at the top and bottom of the hollow 221 of the mold 22, the end of the punch 23, is combined with a pressing means 24, which will be described later. The punch 23 is formed from a heat resistant material such as graphite through the electrical, and tungsten oxide, tungsten.

The pressing means (24) is connected to said punch (23), provides a driving force so that the punch 23 can be moved up and down within the hollow 221 of the die 22.

The power supply section 25 is configured to generate electricity to flow an electric raw material 3 in the mold 22, the power supply section 25 of the pressing means 24, the punch 23, a mold (22 ) it is electrically connected to the. By operating the power supply section (25) communicated to the electrical material 3 within the mold 22, the raw material (3) to generate heat is to be sintered.

The control unit (not shown) in a configuration for controlling the overall operation, by operating the pressure means 24 by operating the press, or the power supply 24 is the raw material (3) the raw material (3) of the electric current sintering apparatus 2 It acts such as electricity flows.

Referring to Figure 1 to 7, and a method of preparing a porous cage according to one embodiment of the present invention is ready to insert the step of making the insert 11 that serve to reinforce the strength of the cage (1) (S1); Filling step (S2) of filling the inserts (11) and the material (3) in the mold and; It has a porosity comprises a sintering step (S3) for producing the structure 12 surrounding the outer surface of the insert 11.

The insert preparation step (S1) is ready for the insert 11, such as a step of manufacturing a insert 11 which serves to reinforce the strength of the cage (1), and Fig. Production method of the insert 11 will be made according to the method of manufacturing the conventional implant, so need not be described in detail here.

The filling operation (S2) is the raw material (3 in the raw material 3 and the mold insert 11 is formed in the insertion space 22 and the punch 23 is prepared to have a specific shape, and the die 22 ) and a step of inserting the insert 11, and are each movable up and down at the top and bottom of the mold 22 is coupled to the punch (23).

Modifying the shape of the raw material 3 and the insert 11 is a mold 22 and doemeuro located in the space (S) formed by the punch 23, the product is manufactured, the die 22 and the punch 23 and it is possible to manufacture a structure 12 of various shapes to be won. Raw material to 10 to 2000㎛ size metal powder and / or ceramic powder is used in the raw material may be in the form of spherical or irregular shape. The metal powder is titanium (Titanium), titanium alloy (Titanium alloy), a cobalt chromium (Cobalt chromium), cobalt-chrome alloy (Cobalt chromium alloy), tantalum (Tantalum), tantalum alloy (Tantalum alloy), niobium (niobium), niobium alloys can be any one or more metal powders selected from the group consisting of used (niobium alloy) and the nitride titanium (titanium nitride). The ceramic powder has a tricalcium phosphate ceramic powder least one selected from the group consisting of calcium (Tricalcium phosphate), hydroxyapatite (Hydroxyapatite), zirconia (Zirconia) and alumina (Alumina) may be used.

The sintering step (S3) is a step of producing the structure 12 by pressing and conducting the raw material (3) located outside the insert (11) has a porous sintered at a constant temperature that surrounds the outer surface of the insert 11 . And the sintering step (S3) comprises a step of inserting a mold (S31), the vacuum creating step (S32), and energizing the pressing step (S33).

The mold inserting step (S31) is a cavity casing (21 of the raw material 3 and the insert 11 is inserted and the punch 23 has a combined die 22 electric current sintering device 2 in the filling step (S2) ) on the insert and further comprising: coupling the punch 23, the pressing section 24.

The vacuum creating step (S32) is a step of creating a vacuum atmosphere of the inside of the casing cavity (21) after the mold insertion step (S31).

The pressure and the energizing step (S33) is a step of sintering at a constant temperature and pressure by conducting the raw material (3) which is located on the outside of the insert 11 in the die 22 is controlled by a control unit. The pressure and the energizing step (S33) is the said control unit by operating the pressing portion 24 is caused to generate electricity at the same time the power supply (25) for pressing in the raw material (3) slide die 22 to punch 23, electricity to flow along the pressing portion 24, the punch 23, the die 22 thereby energizing the raw material (3). In the pressing and energizing step (S33), so the raw material (3), the electricity flows Joule heat occurs, the punch 23 at the same time is pressed, the mold 22 and the raw material (3) raw material 3 is locally dissolved in It is to be coupled. That is, the coupling to the outside of the insert 11 and porous structure 12 are a number of pores formed it is to be manufactured. It is preferable that the above pressing and energizing step (S33) was added to a pressure of 100 to 2000㎏f / ㎠, sintered at a temperature of 800 to 1400 ℃, and generates an electrical current in the range of 500 to 2000A and the voltage of 3 to 7V .

Figure 4 is, multiple pores as shown in the SEM photograph of Figure 5 taken at the outer surface of a porous cage 1 shown in Fig. 4 inde one example of a porous cage (1) produced by the production method of the porous cage it can be seen that it is formed. The porous cage (1) is die 22 and the punch 23 can be achieved which is capable to have a variety of forms, but the raw material particle size on the method by changing the form of the pores by adjusting the pressure such as applied in the sintering step the size and porosity can be easily adjusted.

In the above, the applicant has been described various embodiments of the invention, these embodiments are an example only of one embodiment of implementing the technical idea of ​​the present invention, by any modification or modified examples of implementing the technical idea of ​​the present invention the invention the to be construed as falling within the scope.

Claims (9)

  1. In which is inserted between the adjacent vertebral bodies using a vertebral fusion cage,
    And the cage is of a non-porous insert; Includes; porosity of the structure surrounding the outer surface of the insert
    The insert comprises a connecting portion that is connected to the surgical instrument that is used for the operation of the cage, is projected in an upper surface of the connecting portion an extension extending a predetermined length in the longitudinal direction of the cage,
    The structure is formed so as to contact the outer surface of the upper surface and extending portions of the connecting portion, a porous cage for fusion between the vertebral bodies, characterized in that while maintaining the porous structure by the same time the strength is reinforced by the insert.
  2. 2. The method of claim 1, wherein the extending portion
    Along the outer side including the embedded groove formed is embedded at a predetermined depth, for increasing the area of ​​contact with the extension part of the structure, fusion between the vertebral bodies, characterized in that it can be rigidly coupled to the structure to the insert porous cage.
  3. The method of claim 1, wherein the structure
    Porous cage for fusion between the vertebral bodies, characterized in that having a porosity of 10 to 80%.
  4. The method of claim 1, wherein the connecting portion
    When the constriction is formed in a porous cage for fusion between the vertebral bodies, characterized in that it comprises a coupling groove that surgical instruments used for the operation of the cage to be inserted.
  5. According to claim 1,
    The length of the structure is a porous cage for fusion between the vertebral bodies, characterized in that more than 1 to 70% longer length of the extension.
  6. According to claim 1,
    The length of the structure is a porous cage for fusion between the vertebral bodies, characterized in that more than 1 to 20% longer length of the extension.
  7. The method of claim 1, wherein the structure
    Filling the insert and the material in the mold and filled in the mold by using the electric current sintering device is that by passing the raw material at the same time applies a constant pressure to the raw material located outside of the insert made by sintering the material at a constant temperature porous cage for fusion between the vertebral bodies, characterized in that.
  8. The method of claim 7,
    The pressure is 100 to 2000㎏f / ㎠,
    The temperature is from 800 to 1400 ℃,
    Porous cage for fusion between the vertebral bodies, characterized in that applying a 500 to current and a voltage of 3 to 7V of 2000A to conducting the above-mentioned material.
  9. The method of claim 7, wherein the material is
    The metal powder or ceramic powder,
    The metal is at least one selected from the group consisting of titanium, titanium alloys, cobalt chromium, cobalt chromium alloys, tantalum, tantalum alloys, niobium (niobium), niobium alloys (niobium alloy) and titanium nitride,
    The ceramic is a porous cage for fusion between the vertebral bodies, characterized in that at least one selected from the group consisting of tricalcium phosphate, hydroxyapatite, zirconia and alumina.
PCT/KR2012/006304 2011-09-28 2012-08-08 Porous cage for intervertebral fusion, and method for manufacturing same WO2013048000A2 (en)

Priority Applications (2)

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US9216096B2 (en) 2010-03-16 2015-12-22 Pinnacle Spine Group, Llc Intervertebral implants and related tools
US9380932B1 (en) 2011-11-02 2016-07-05 Pinnacle Spine Group, Llc Retractor devices for minimally invasive access to the spine
US10070970B2 (en) 2013-03-14 2018-09-11 Pinnacle Spine Group, Llc Interbody implants and graft delivery systems

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KR20130034283A (en) * 2011-09-28 2013-04-05 주식회사 코렌텍 Manufacturing method for porous implant and porous implant produced thereof
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US10070970B2 (en) 2013-03-14 2018-09-11 Pinnacle Spine Group, Llc Interbody implants and graft delivery systems

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