WO2012093971A3 - Effervescent compositions comprising amlodipine - Google Patents

Effervescent compositions comprising amlodipine Download PDF

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Publication number
WO2012093971A3
WO2012093971A3 PCT/TR2012/000002 TR2012000002W WO2012093971A3 WO 2012093971 A3 WO2012093971 A3 WO 2012093971A3 TR 2012000002 W TR2012000002 W TR 2012000002W WO 2012093971 A3 WO2012093971 A3 WO 2012093971A3
Authority
WO
WIPO (PCT)
Prior art keywords
amlodipine
effervescent compositions
formulations
effervescent
compositions
Prior art date
Application number
PCT/TR2012/000002
Other languages
French (fr)
Other versions
WO2012093971A2 (en
Inventor
Mahmut Bilgic
Original Assignee
Mahmut Bilgic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mahmut Bilgic filed Critical Mahmut Bilgic
Publication of WO2012093971A2 publication Critical patent/WO2012093971A2/en
Publication of WO2012093971A3 publication Critical patent/WO2012093971A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats

Abstract

The present invention relates to easy-to-use effervescent formulations with improved stability comprising amlodipine or a pharmaceutically acceptable derivative thereof and use of these formulations in treatment of hypertension.
PCT/TR2012/000002 2011-01-06 2012-01-06 Effervescent compositions comprising amlodipine WO2012093971A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
TR2011/00152 2011-01-06
TR2011/00152A TR201100152A2 (en) 2011-01-06 2011-01-06 Effervescent compositions containing amlodipine.

Publications (2)

Publication Number Publication Date
WO2012093971A2 WO2012093971A2 (en) 2012-07-12
WO2012093971A3 true WO2012093971A3 (en) 2012-09-20

Family

ID=45855989

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/TR2012/000002 WO2012093971A2 (en) 2011-01-06 2012-01-06 Effervescent compositions comprising amlodipine

Country Status (2)

Country Link
TR (1) TR201100152A2 (en)
WO (1) WO2012093971A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104055742B (en) * 2014-02-13 2018-01-19 合肥九研医药科技开发有限公司 Levamlodipine besylate pharmaceutical composition and preparation method thereof
CN105310992B (en) * 2015-10-16 2018-11-09 施慧达药业集团(吉林)有限公司 The tablet composition of Levamlodipine besylate salt hydrate, the tablet being made from it and related manufacturing processes

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0582169A2 (en) * 1992-08-05 1994-02-09 Bayer S.p.A. Pharmaceutical preparations for the oral administration of dihydropyridines in beverage form
WO1995027482A1 (en) * 1994-04-06 1995-10-19 Elan Corporation, Plc Effervescent pharmaceutical formulations containing controlled release biodegradable microcapsules
WO2000057857A1 (en) * 1999-03-25 2000-10-05 Yuhan Corporation Rapidly disintegrable tablet for oral administration
EP1839650A1 (en) * 2004-12-28 2007-10-03 Eisai R&D Management Co., Ltd. Quick disintegration tablet and method of producing the same
WO2011152803A1 (en) * 2010-06-03 2011-12-08 Mahmut Bilgic Water soluble formulation comprising a combination of amlodipine and a statin

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK161312C (en) 1982-03-11 1991-12-09 Pfizer CHANGES FOR THE PREPARATION FOR THE PREPARATION OF 2-Amino-CO-Methyl-4-Methyl-4-Methyl-4-Methyl-4-Methyl-4-Methyl-4-Methyl-2-D-Hydroxy

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0582169A2 (en) * 1992-08-05 1994-02-09 Bayer S.p.A. Pharmaceutical preparations for the oral administration of dihydropyridines in beverage form
WO1995027482A1 (en) * 1994-04-06 1995-10-19 Elan Corporation, Plc Effervescent pharmaceutical formulations containing controlled release biodegradable microcapsules
WO2000057857A1 (en) * 1999-03-25 2000-10-05 Yuhan Corporation Rapidly disintegrable tablet for oral administration
EP1839650A1 (en) * 2004-12-28 2007-10-03 Eisai R&D Management Co., Ltd. Quick disintegration tablet and method of producing the same
WO2011152803A1 (en) * 2010-06-03 2011-12-08 Mahmut Bilgic Water soluble formulation comprising a combination of amlodipine and a statin

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BARMPALEXIS PANAGIOTIS ET AL: "Solid dispersions in the development of a nimodipine floating tablet formulation and optimization by artificial neural networks and genetic programming", EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, vol. 77, no. 1, January 2011 (2011-01-01), pages 122 - 131, XP027571352, ISSN: 0939-6411 *

Also Published As

Publication number Publication date
WO2012093971A2 (en) 2012-07-12
TR201100152A2 (en) 2012-07-23

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