WO2012046238A3 - Erythropoietin receptor antagonists - Google Patents

Erythropoietin receptor antagonists Download PDF

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Publication number
WO2012046238A3
WO2012046238A3 PCT/IL2011/000788 IL2011000788W WO2012046238A3 WO 2012046238 A3 WO2012046238 A3 WO 2012046238A3 IL 2011000788 W IL2011000788 W IL 2011000788W WO 2012046238 A3 WO2012046238 A3 WO 2012046238A3
Authority
WO
WIPO (PCT)
Prior art keywords
erythropoietin
erythropoietin receptor
receptor antagonists
cell proliferation
induced
Prior art date
Application number
PCT/IL2011/000788
Other languages
English (en)
French (fr)
Other versions
WO2012046238A2 (en
Inventor
Tamar Liron
Miriam Souroujon
Drorit Neumann
Original Assignee
Ramot At Tel-Aviv University Ltd.
Opmop Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ramot At Tel-Aviv University Ltd., Opmop Ltd. filed Critical Ramot At Tel-Aviv University Ltd.
Publication of WO2012046238A2 publication Critical patent/WO2012046238A2/en
Publication of WO2012046238A3 publication Critical patent/WO2012046238A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/505—Erythropoietin [EPO]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
PCT/IL2011/000788 2010-10-06 2011-10-06 Erythropoietin receptor antagonists WO2012046238A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39025310P 2010-10-06 2010-10-06
US61/390,253 2010-10-06

Publications (2)

Publication Number Publication Date
WO2012046238A2 WO2012046238A2 (en) 2012-04-12
WO2012046238A3 true WO2012046238A3 (en) 2012-08-09

Family

ID=44971068

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2011/000788 WO2012046238A2 (en) 2010-10-06 2011-10-06 Erythropoietin receptor antagonists

Country Status (1)

Country Link
WO (1) WO2012046238A2 (nl)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6048971A (en) * 1992-07-28 2000-04-11 Beth Israel Deaconess Medical Center Recombinant human erythropoietin mutants
WO2004003176A2 (en) * 2002-07-01 2004-01-08 The Kenneth S. Warren Institute, Inc. Recombinant tissue protective cytokines and encoding nucleic acids thereof for protection, restoration, and enhancement of responsive cells, tissues, and organs
WO2004031211A2 (en) * 2002-10-03 2004-04-15 Epimmune Inc. Hla binding peptides and their uses

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE141646T1 (de) 1986-04-09 1996-09-15 Genzyme Corp Genetisch transformierte tiere, die ein gewünschtes protein in milch absondern
US4873316A (en) 1987-06-23 1989-10-10 Biogen, Inc. Isolation of exogenous recombinant proteins from the milk of transgenic mammals
US5464764A (en) 1989-08-22 1995-11-07 University Of Utah Research Foundation Positive-negative selection methods and vectors
US5541110A (en) 1994-05-17 1996-07-30 Bristol-Myers Squibb Cloning and expression of a gene encoding bryodin 1 from Bryonia dioica

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6048971A (en) * 1992-07-28 2000-04-11 Beth Israel Deaconess Medical Center Recombinant human erythropoietin mutants
WO2004003176A2 (en) * 2002-07-01 2004-01-08 The Kenneth S. Warren Institute, Inc. Recombinant tissue protective cytokines and encoding nucleic acids thereof for protection, restoration, and enhancement of responsive cells, tissues, and organs
WO2004031211A2 (en) * 2002-10-03 2004-04-15 Epimmune Inc. Hla binding peptides and their uses

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DATABASE Geneseq [online] 25 March 2004 (2004-03-25), "Human erythropoietin peptide fragment SEQ ID NO:3.", XP002668527, retrieved from EBI accession no. GSP:ADH43893 Database accession no. ADH43893 *

Also Published As

Publication number Publication date
WO2012046238A2 (en) 2012-04-12

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