WO2012044671A3 - Method for removing residual organic solvent from microparticles - Google Patents
Method for removing residual organic solvent from microparticles Download PDFInfo
- Publication number
- WO2012044671A3 WO2012044671A3 PCT/US2011/053655 US2011053655W WO2012044671A3 WO 2012044671 A3 WO2012044671 A3 WO 2012044671A3 US 2011053655 W US2011053655 W US 2011053655W WO 2012044671 A3 WO2012044671 A3 WO 2012044671A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- microparticles
- organic solvent
- removing residual
- residual organic
- microparticle
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Biological Depolymerization Polymers (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
Abstract
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2013531765A JP5808413B2 (en) | 2010-09-30 | 2011-09-28 | Method for removing residual organic solvent from fine particles |
AU2011308893A AU2011308893B2 (en) | 2010-09-30 | 2011-09-28 | Method for removing residual organic solvent from microparticles |
EP11771308.1A EP2621473A2 (en) | 2010-09-30 | 2011-09-28 | Method for removing residual organic solvent from microparticles |
CA2813301A CA2813301A1 (en) | 2010-09-30 | 2011-09-28 | Method for removing residual organic solvent from microparticles |
CN2011800471235A CN103370057A (en) | 2010-09-30 | 2011-09-28 | Method for removing residual organic solvent from microparticles |
RU2013119811/05A RU2013119811A (en) | 2010-09-30 | 2011-09-28 | METHOD FOR REMOVING RESIDUAL ORGANIC SOLVENT FROM MICROPARTICLES |
IL225254A IL225254A0 (en) | 2010-09-30 | 2013-03-17 | Method for removing residual organic solvent from microparticles |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US38805010P | 2010-09-30 | 2010-09-30 | |
US61/388,050 | 2010-09-30 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2012044671A2 WO2012044671A2 (en) | 2012-04-05 |
WO2012044671A3 true WO2012044671A3 (en) | 2013-03-14 |
Family
ID=45094869
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2011/053655 WO2012044671A2 (en) | 2010-09-30 | 2011-09-28 | Method for removing residual organic solvent from microparticles |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP2621473A2 (en) |
JP (1) | JP5808413B2 (en) |
CN (1) | CN103370057A (en) |
AU (1) | AU2011308893B2 (en) |
CA (1) | CA2813301A1 (en) |
IL (1) | IL225254A0 (en) |
RU (1) | RU2013119811A (en) |
WO (1) | WO2012044671A2 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104382848B (en) * | 2014-10-20 | 2017-04-26 | 齐鲁制药有限公司 | Tacrolimus suspending eye drop liquid and preparation method thereof |
CN109718209B (en) * | 2017-10-30 | 2021-03-05 | 浙江圣兆药物科技股份有限公司 | Freeze-drying method of risperidone microspheres with low ethanol residues |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4637905A (en) * | 1982-03-04 | 1987-01-20 | Batelle Development Corporation | Process of preparing microcapsules of lactides or lactide copolymers with glycolides and/or ε-caprolactones |
US5876761A (en) * | 1989-07-07 | 1999-03-02 | Novartis Ag | Sustained release formulations of water soluble peptides |
US20050181059A1 (en) * | 2003-09-30 | 2005-08-18 | Spherics, Inc. | Nanoparticulate therapeutic biologically active agents |
US20080317865A1 (en) * | 2007-06-20 | 2008-12-25 | Alkermes, Inc. | Quench liquids and washing systems for production of microparticles |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2084698T5 (en) | 1989-05-04 | 2005-03-01 | Southern Research Institute | ENCAPSULATION PROCEDURE. |
HU221294B1 (en) * | 1989-07-07 | 2002-09-28 | Novartis Ag | Process for producing retarde compositions containing the active ingredient in a polymeric carrier |
US5739265A (en) * | 1995-09-20 | 1998-04-14 | Clariant Finance (Bvi) Ltd. | Fractionation of phenol formaldehyde condensate and photoresist compositions produced therefrom |
US6824822B2 (en) * | 2001-08-31 | 2004-11-30 | Alkermes Controlled Therapeutics Inc. Ii | Residual solvent extraction method and microparticles produced thereby |
-
2011
- 2011-09-28 JP JP2013531765A patent/JP5808413B2/en not_active Expired - Fee Related
- 2011-09-28 AU AU2011308893A patent/AU2011308893B2/en not_active Ceased
- 2011-09-28 RU RU2013119811/05A patent/RU2013119811A/en not_active Application Discontinuation
- 2011-09-28 CN CN2011800471235A patent/CN103370057A/en active Pending
- 2011-09-28 WO PCT/US2011/053655 patent/WO2012044671A2/en active Application Filing
- 2011-09-28 CA CA2813301A patent/CA2813301A1/en not_active Abandoned
- 2011-09-28 EP EP11771308.1A patent/EP2621473A2/en not_active Withdrawn
-
2013
- 2013-03-17 IL IL225254A patent/IL225254A0/en unknown
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4637905A (en) * | 1982-03-04 | 1987-01-20 | Batelle Development Corporation | Process of preparing microcapsules of lactides or lactide copolymers with glycolides and/or ε-caprolactones |
US5876761A (en) * | 1989-07-07 | 1999-03-02 | Novartis Ag | Sustained release formulations of water soluble peptides |
US20050181059A1 (en) * | 2003-09-30 | 2005-08-18 | Spherics, Inc. | Nanoparticulate therapeutic biologically active agents |
US20080317865A1 (en) * | 2007-06-20 | 2008-12-25 | Alkermes, Inc. | Quench liquids and washing systems for production of microparticles |
Also Published As
Publication number | Publication date |
---|---|
WO2012044671A2 (en) | 2012-04-05 |
AU2011308893B2 (en) | 2015-04-23 |
CA2813301A1 (en) | 2012-04-05 |
EP2621473A2 (en) | 2013-08-07 |
JP5808413B2 (en) | 2015-11-10 |
AU2011308893A1 (en) | 2013-05-09 |
IL225254A0 (en) | 2013-06-27 |
CN103370057A (en) | 2013-10-23 |
RU2013119811A (en) | 2014-11-10 |
JP2013538854A (en) | 2013-10-17 |
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