WO2012037349A3 - Composés - Google Patents

Composés Download PDF

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Publication number
WO2012037349A3
WO2012037349A3 PCT/US2011/051761 US2011051761W WO2012037349A3 WO 2012037349 A3 WO2012037349 A3 WO 2012037349A3 US 2011051761 W US2011051761 W US 2011051761W WO 2012037349 A3 WO2012037349 A3 WO 2012037349A3
Authority
WO
WIPO (PCT)
Prior art keywords
compounds
trpc3
pharmaceutical compositions
compositions containing
ion channels
Prior art date
Application number
PCT/US2011/051761
Other languages
English (en)
Other versions
WO2012037349A2 (fr
Inventor
Jason W. Dodson
Joseph Paul Marino Jr.
John Jeffrey Mcatee
Lamont Roscoe Terrell
David G. Washburn
Original Assignee
Glaxosmithkline Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Llc filed Critical Glaxosmithkline Llc
Publication of WO2012037349A2 publication Critical patent/WO2012037349A2/fr
Publication of WO2012037349A3 publication Critical patent/WO2012037349A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

composés, compositions pharmaceutiques les contenant, et leur utilisation pour traiter les affections médiées par les canaux ioniques TRPC3 et/ou TRPC6.
PCT/US2011/051761 2010-09-17 2011-09-15 Composés WO2012037349A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38388510P 2010-09-17 2010-09-17
US61/383,885 2010-09-17

Publications (2)

Publication Number Publication Date
WO2012037349A2 WO2012037349A2 (fr) 2012-03-22
WO2012037349A3 true WO2012037349A3 (fr) 2014-03-27

Family

ID=45832238

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2011/051761 WO2012037349A2 (fr) 2010-09-17 2011-09-15 Composés

Country Status (1)

Country Link
WO (1) WO2012037349A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014016766A1 (fr) 2012-07-25 2014-01-30 Glenmark Pharmaceuticals S.A. Utilisation de dérivés de la guanidine comme modulateurs des canaux trpc
WO2017123759A1 (fr) * 2016-01-12 2017-07-20 Zanella Fabian Formulation de milieu cellulaire pour la stabilisation de cellules
CN111770918B (zh) * 2018-02-15 2024-02-27 勃林格殷格翰国际公司 Trpc6的抑制剂
AR121846A1 (es) 2020-04-16 2022-07-13 Teijin Pharma Ltd Derivado de arilo o heteroarilo
CN116261453A (zh) 2020-08-13 2023-06-13 勃林格殷格翰国际有限公司 与思觉失调症相关的认知障碍的治疗

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040077643A1 (en) * 2000-08-01 2004-04-22 Mikio Ogawa 3,4 Dihydroisoquinoline derivative compounds and drugs containing these compounds as the active ingredient
US20070004711A1 (en) * 2005-05-09 2007-01-04 Suoming Zhang Thiazole compounds and methods of use

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040077643A1 (en) * 2000-08-01 2004-04-22 Mikio Ogawa 3,4 Dihydroisoquinoline derivative compounds and drugs containing these compounds as the active ingredient
US20070004711A1 (en) * 2005-05-09 2007-01-04 Suoming Zhang Thiazole compounds and methods of use

Also Published As

Publication number Publication date
WO2012037349A2 (fr) 2012-03-22

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