WO2011124667A3 - Verfahren zur herstellung von im wesentlichen kugelförmigen lyophilisaten - Google Patents

Verfahren zur herstellung von im wesentlichen kugelförmigen lyophilisaten Download PDF

Info

Publication number
WO2011124667A3
WO2011124667A3 PCT/EP2011/055476 EP2011055476W WO2011124667A3 WO 2011124667 A3 WO2011124667 A3 WO 2011124667A3 EP 2011055476 W EP2011055476 W EP 2011055476W WO 2011124667 A3 WO2011124667 A3 WO 2011124667A3
Authority
WO
WIPO (PCT)
Prior art keywords
preparation
lyophilisates
essentially spherical
essentially
spherical
Prior art date
Application number
PCT/EP2011/055476
Other languages
English (en)
French (fr)
Other versions
WO2011124667A2 (de
Inventor
Andy Wende
Markus Jesziorski
Original Assignee
Qiagen Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Qiagen Gmbh filed Critical Qiagen Gmbh
Publication of WO2011124667A2 publication Critical patent/WO2011124667A2/de
Publication of WO2011124667A3 publication Critical patent/WO2011124667A3/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Beschrieben wird ein Verfahren zur Herstellung von einem im Wesentlichen kugelförmigen Festkörper durch Gefriertrocknung,
PCT/EP2011/055476 2010-04-09 2011-04-08 Verfahren zur herstellung von im wesentlichen kugelförmigen lyophilisaten WO2011124667A2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP10159453.9 2010-04-09
EP10159453 2010-04-09

Publications (2)

Publication Number Publication Date
WO2011124667A2 WO2011124667A2 (de) 2011-10-13
WO2011124667A3 true WO2011124667A3 (de) 2011-12-29

Family

ID=42154234

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2011/055476 WO2011124667A2 (de) 2010-04-09 2011-04-08 Verfahren zur herstellung von im wesentlichen kugelförmigen lyophilisaten

Country Status (1)

Country Link
WO (1) WO2011124667A2 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013066769A1 (en) 2011-10-31 2013-05-10 Merck Sharp & Dohme Corp. Methods of preparing lyophilized spherical-shaped pellets of biological materials

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2016285C (en) * 1989-08-01 1998-10-20 Ortech Corporation Production of spherical ceramic powders
WO2003020959A1 (en) * 2001-09-05 2003-03-13 Btf Pty Ltd Products containing quantum of bioparticles and method for production thereof
WO2005058474A1 (en) * 2003-12-19 2005-06-30 Alk-Abelló A/S Cryogranulation and storage method for active pharmaceutical agents
EP2168557A2 (de) * 2008-09-25 2010-03-31 Nitto Denko Corporation Herstellungsverfahren für Gelatinpartikel

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6436715B1 (en) 1999-07-01 2002-08-20 Degussa Huls Ag Method for determining silicone concentrations
US20050069898A1 (en) 2003-09-25 2005-03-31 Cepheid Lyophilized beads containing mannitol
US20070259348A1 (en) 2005-05-03 2007-11-08 Handylab, Inc. Lyophilized pellets
WO2008144063A1 (en) 2007-05-21 2008-11-27 Tate & Lyle Technology Ltd. Freeze dried sucralose

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2016285C (en) * 1989-08-01 1998-10-20 Ortech Corporation Production of spherical ceramic powders
WO2003020959A1 (en) * 2001-09-05 2003-03-13 Btf Pty Ltd Products containing quantum of bioparticles and method for production thereof
WO2005058474A1 (en) * 2003-12-19 2005-06-30 Alk-Abelló A/S Cryogranulation and storage method for active pharmaceutical agents
EP2168557A2 (de) * 2008-09-25 2010-03-31 Nitto Denko Corporation Herstellungsverfahren für Gelatinpartikel

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
SCHMIDT D J ET AL: "CRYOGRANULATION: A POTENTIAL NEW FINAL PROCESS FOR BULK DRUG SUBSTANCES", BIOPHARM, CLEVELAND,OH, US, 1 April 1997 (1997-04-01), pages 28,30,32, XP002914615 *

Also Published As

Publication number Publication date
WO2011124667A2 (de) 2011-10-13

Similar Documents

Publication Publication Date Title
ZA201206095B (en) Process for the preparation of isoxazoline derivatives
WO2012025944A3 (en) Sitagliptin, salts and polymorphs thereof
WO2010117738A3 (en) Solid state forms of sitagliptin salts
EP2530049A4 (de) Verfahren zur herstellung eines pulvers aus aluminiumnitridkugeln sowie in diesem verfahren hergestelltes pulver aus aluminiumnitridkugeln
EP2622828A4 (de) Vorrichtung mit einem elastisch transformierbaren körper
WO2011133504A3 (en) Nanozymes, methods of making nanozymes, and methods of using nanozymes
EP2648863A4 (de) Verbesserte feinguss-formschalen mit einer organischen komponente
EP2660829A4 (de) Magnetkörper
WO2011060213A3 (en) Preparation of sitagliptin and salts thereof
PL2531505T3 (pl) Sposób wytwarzania kompleksów 3,7-diaza-bicyklo[3.3.1]nonanu z metalami
WO2014041560A3 (en) Process for the preparation of teneligliptin
IL229993A0 (en) A process for the preparation of 8-Alkoxy[1,2,4]triazolo[5,1-c]pyrimidine-2 amines 5-converted
WO2011139886A3 (en) Preparation of febuxostat
WO2011079193A3 (en) Preparation of bendamustine and its salts
ZA201300776B (en) Improved process for the preparation of febuxostat
EP2589484A4 (de) Verfahren zur herstellung eines formkörpers
WO2011025932A3 (en) Preparation of sitagliptin and salts thereof
WO2012054782A3 (en) Fluoroalkoxylation of organic compounds
WO2010148314A3 (en) Preparation of esomeprazole and its pharmaceutically acceptable salts
WO2011088020A9 (en) Modified saponins for the treatment of fungal infections
PL2582711T3 (pl) Sposób wytwarzania pochodnych pterydyny
IL225680A0 (en) Process for preparing 3-(6-amino-pyridin-3-yl)2-acrylic acid derivatives
WO2010148209A3 (en) Preparation of montelukast
EP2545023A4 (de) Verfahren zur herstellung von scyllo-inositol
WO2010091169A3 (en) Preparation of valsartan

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 11712870

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 11712870

Country of ref document: EP

Kind code of ref document: A2