WO2011111066A3 - Composition and uses thereof - Google Patents
Composition and uses thereof Download PDFInfo
- Publication number
- WO2011111066A3 WO2011111066A3 PCT/IN2011/000154 IN2011000154W WO2011111066A3 WO 2011111066 A3 WO2011111066 A3 WO 2011111066A3 IN 2011000154 W IN2011000154 W IN 2011000154W WO 2011111066 A3 WO2011111066 A3 WO 2011111066A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- hypertriglyceridemia
- hyperglycemia
- prophylaxis
- diabetes
- inhibitor
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
Abstract
The present invention relates generally to pharmaceutical compositions and their use for the prophylaxis or treatment of conditions associated with hyperglycemia or hypertriglyceridemia, including (but not limited to), diabetes (e.g., Type 2 diabetes) and obesity. The present invention also relates to methods of prophylaxis or treatment of such conditions, based on the finding that an inhibitor of a phosphodiesterase 3 activity and an inhibitor of angiotensin receptor activity provide a desirable synergistic effect on hyperglycemia and hypertriglyceridemia.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN664/CHE/2010 | 2010-03-12 | ||
IN664CH2010 | 2010-03-12 | ||
US32994410P | 2010-04-30 | 2010-04-30 | |
US61/329,944 | 2010-04-30 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2011111066A2 WO2011111066A2 (en) | 2011-09-15 |
WO2011111066A3 true WO2011111066A3 (en) | 2012-03-29 |
Family
ID=44563940
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IN2011/000154 WO2011111066A2 (en) | 2010-03-12 | 2011-03-09 | Composition and uses thereof |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2011111066A2 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT3034071T (en) | 2011-12-21 | 2018-01-19 | Elanco Tiergesundheit Ag | New combination |
HUE060093T2 (en) | 2012-03-15 | 2023-01-28 | Boehringer Ingelheim Vetmedica Gmbh | Pharmaceutical tablet formulation for the veterinary medical sector, method of production and use thereof |
IL306091A (en) * | 2021-05-11 | 2023-11-01 | Regeneron Pharma | Methods of treating liver diseases with phosphodiesterase 3b (pde3b) inhibitors |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5830909A (en) * | 1993-06-28 | 1998-11-03 | American Cyanamid Company | Angiotensin (AII) antagonists as inhibitors of the growth of adipose tissue |
US5981470A (en) * | 1994-06-07 | 1999-11-09 | The University Of Birmingham | Uterine fibroid treatment |
US20070208029A1 (en) * | 2005-10-21 | 2007-09-06 | Braincells, Inc. | Modulation of neurogenesis by pde inhibition |
US20080004283A1 (en) * | 2005-12-06 | 2008-01-03 | Menarini Ricerche S.P.A. | Pharmaceutical Compositions for the Treatment of Cellulite |
US20080167291A1 (en) * | 2006-05-09 | 2008-07-10 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
-
2011
- 2011-03-09 WO PCT/IN2011/000154 patent/WO2011111066A2/en active Application Filing
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5830909A (en) * | 1993-06-28 | 1998-11-03 | American Cyanamid Company | Angiotensin (AII) antagonists as inhibitors of the growth of adipose tissue |
US5981470A (en) * | 1994-06-07 | 1999-11-09 | The University Of Birmingham | Uterine fibroid treatment |
US20070208029A1 (en) * | 2005-10-21 | 2007-09-06 | Braincells, Inc. | Modulation of neurogenesis by pde inhibition |
US20080004283A1 (en) * | 2005-12-06 | 2008-01-03 | Menarini Ricerche S.P.A. | Pharmaceutical Compositions for the Treatment of Cellulite |
US20080167291A1 (en) * | 2006-05-09 | 2008-07-10 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
Also Published As
Publication number | Publication date |
---|---|
WO2011111066A2 (en) | 2011-09-15 |
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