WO2011096782A3 - Liquid flow apparatus, fixed quantity liquid supply apparatus, and target substance extracting apparatus and target substance extracting method using the two apparatuses - Google Patents

Liquid flow apparatus, fixed quantity liquid supply apparatus, and target substance extracting apparatus and target substance extracting method using the two apparatuses Download PDF

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Publication number
WO2011096782A3
WO2011096782A3 PCT/KR2011/000832 KR2011000832W WO2011096782A3 WO 2011096782 A3 WO2011096782 A3 WO 2011096782A3 KR 2011000832 W KR2011000832 W KR 2011000832W WO 2011096782 A3 WO2011096782 A3 WO 2011096782A3
Authority
WO
WIPO (PCT)
Prior art keywords
liquid
substances
reaction chamber
target substance
liquid flow
Prior art date
Application number
PCT/KR2011/000832
Other languages
French (fr)
Korean (ko)
Other versions
WO2011096782A2 (en
Inventor
서유진
Original Assignee
Seo Yu-Jin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seo Yu-Jin filed Critical Seo Yu-Jin
Priority claimed from KR1020110011136A external-priority patent/KR20110092239A/en
Publication of WO2011096782A2 publication Critical patent/WO2011096782A2/en
Publication of WO2011096782A3 publication Critical patent/WO2011096782A3/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0874—Three dimensional network
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/52—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
    • B01L9/527—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips for microfluidic devices, e.g. used for lab-on-a-chip

Abstract

The present invention relates to a liquid flow apparatus for conducting tests including biochemical reactions, to a fixed quantity liquid supply apparatus for automatically filling the liquid flow apparatus with liquid substances, to a target substance extracting apparatus for extracting target substances such as nucleic acids, protein or the like from a variety of biological samples, using the liquid flow apparatus and the fixed quantity liquid supply apparatus, and to a target substance extraction method for extracting target substances from a variety of biological samples, using magnetic particles which selectively adsorb target substances. In one embodiment of the liquid flow apparatus according to the present invention, a liquid flow plate comprises: a plurality of storage chambers in which liquid substances are stored; a reaction chamber in which two or more liquid substances react with each other; a plurality of delivery channels interposed between the storage chambers and the reaction chamber so as to deliver the liquid substances stored in the storage chambers to the reaction chamber; injection channels for injecting liquid substances into the plurality of storage chambers; and a discharge channel connected to the reaction chamber, wherein pump means connected to the discharge channel operate and simultaneously the plurality of injection channels are selectively opened/closed, to thereby supply the liquid substances stored in the storage chambers to the reaction chamber, or discharge the liquid substances in the reaction chamber to the outside.
PCT/KR2011/000832 2010-02-08 2011-02-08 Liquid flow apparatus, fixed quantity liquid supply apparatus, and target substance extracting apparatus and target substance extracting method using the two apparatuses WO2011096782A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR10-2010-0011669 2010-02-08
KR20100011669 2010-02-08
KR1020110011136A KR20110092239A (en) 2010-02-08 2011-02-08 Liquid flow device, liquid fixed supplier, apparatus for extracting target substance and method for extracting target substance using the same
KR10-2011-0011136 2011-02-08

Publications (2)

Publication Number Publication Date
WO2011096782A2 WO2011096782A2 (en) 2011-08-11
WO2011096782A3 true WO2011096782A3 (en) 2012-02-23

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2011/000832 WO2011096782A2 (en) 2010-02-08 2011-02-08 Liquid flow apparatus, fixed quantity liquid supply apparatus, and target substance extracting apparatus and target substance extracting method using the two apparatuses

Country Status (1)

Country Link
WO (1) WO2011096782A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150293097A1 (en) 2012-10-08 2015-10-15 General Electric Company Preloaded test substrates for testing lal-reactive substances, methods of use, and methods of making
KR101996617B1 (en) * 2018-10-11 2019-07-04 주식회사 엘지화학 Integrated cartridge
CN114100957B (en) * 2020-08-26 2023-03-24 湖北万度光能有限责任公司 Slit coating system containing feed liquid suck-back channel

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3970518A (en) * 1975-07-01 1976-07-20 General Electric Company Magnetic separation of biological particles
US6187270B1 (en) * 1994-07-07 2001-02-13 Roche Diagnostics Gmbh Device and method for the separation of magnetic microparticles
US6663833B1 (en) * 1998-03-10 2003-12-16 Strategic Diagnostics Inc. Integrated assay device and methods of production and use
US20050265899A1 (en) * 2002-08-06 2005-12-01 Canon Kabushiki Kaisha Liquid transfer apparatus and method of manufacturing the same

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3970518A (en) * 1975-07-01 1976-07-20 General Electric Company Magnetic separation of biological particles
US6187270B1 (en) * 1994-07-07 2001-02-13 Roche Diagnostics Gmbh Device and method for the separation of magnetic microparticles
US6663833B1 (en) * 1998-03-10 2003-12-16 Strategic Diagnostics Inc. Integrated assay device and methods of production and use
US20050265899A1 (en) * 2002-08-06 2005-12-01 Canon Kabushiki Kaisha Liquid transfer apparatus and method of manufacturing the same

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ERBACHER, C. ET AL.: "Towards Integrated Continuous-Flow Chemical Reactors.", MIKROCHIM. ACTA., vol. 131, 1999, pages 19 - 24 *

Also Published As

Publication number Publication date
WO2011096782A2 (en) 2011-08-11

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