WO2011081328A3 - Construct for tissue reconstruction and kit for producing a construct for tissue reconstruction - Google Patents

Construct for tissue reconstruction and kit for producing a construct for tissue reconstruction Download PDF

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Publication number
WO2011081328A3
WO2011081328A3 PCT/KR2010/008969 KR2010008969W WO2011081328A3 WO 2011081328 A3 WO2011081328 A3 WO 2011081328A3 KR 2010008969 W KR2010008969 W KR 2010008969W WO 2011081328 A3 WO2011081328 A3 WO 2011081328A3
Authority
WO
WIPO (PCT)
Prior art keywords
construct
tissue reconstruction
kit
producing
voids
Prior art date
Application number
PCT/KR2010/008969
Other languages
French (fr)
Korean (ko)
Other versions
WO2011081328A2 (en
Inventor
이수홍
강선웅
김진수
한인보
신동아
Original Assignee
차의과학대학교 산학협력단
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR1020090133756A external-priority patent/KR101141547B1/en
Priority claimed from KR1020090133762A external-priority patent/KR101162269B1/en
Application filed by 차의과학대학교 산학협력단 filed Critical 차의과학대학교 산학협력단
Publication of WO2011081328A2 publication Critical patent/WO2011081328A2/en
Publication of WO2011081328A3 publication Critical patent/WO2011081328A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/64—Animal cells

Abstract

The present invention provides a construct for tissue reconstruction, comprising a coating layer formed by coating a surface of a frame of a polymer support having voids, with hyaluronic acids or salts thereof and fibrinogens, wherein (i) the coating layer comprises: cells; cell growth factors; or cells and cell growth factors, (ii) the coating layer is cross-linked by thrombin, and (iii) the construct has voids of 10 μm to 1,000 μm. In addition, the present invention provides a kit for producing a construct for tissue reconstruction, which is cross-linked by thrombin and has voids of 10 μm to 1,000 μm.
PCT/KR2010/008969 2009-12-30 2010-12-15 Construct for tissue reconstruction and kit for producing a construct for tissue reconstruction WO2011081328A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR1020090133756A KR101141547B1 (en) 2009-12-30 2009-12-30 Construct for tissue-reconstruction comprising coating layer formed by coating hyaluronic acid or its salt and fibrinogen on surface of support frame
KR10-2009-0133762 2009-12-30
KR1020090133762A KR101162269B1 (en) 2009-12-30 2009-12-30 Kit for forming construct for tissue-reconstruction
KR10-2009-0133756 2009-12-30

Publications (2)

Publication Number Publication Date
WO2011081328A2 WO2011081328A2 (en) 2011-07-07
WO2011081328A3 true WO2011081328A3 (en) 2011-11-10

Family

ID=44226956

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2010/008969 WO2011081328A2 (en) 2009-12-30 2010-12-15 Construct for tissue reconstruction and kit for producing a construct for tissue reconstruction

Country Status (1)

Country Link
WO (1) WO2011081328A2 (en)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20010027979A (en) * 1999-09-17 2001-04-06 오석송 A guided tissue regeneration membrane
KR20010044624A (en) * 2001-03-12 2001-06-05 정재호 A process for preparing the scaffold and tissue engineered cartilage made from the scaffold
KR20030032420A (en) * 2001-10-18 2003-04-26 한국과학기술연구원 Porous Scaffold Made of Biodegradable Polymer for Reconstructing Damaged Ocular Tissue
KR20060091301A (en) * 2003-09-19 2006-08-18 각고호우징 게이오기주크 Composition for coating support for preparation of cell sheet, support for preparation of cell sheet and process for producing cell sheet
US20060246105A1 (en) * 2005-04-28 2006-11-02 Fred Molz Coatings on medical implants to guide soft tissue healing

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20010027979A (en) * 1999-09-17 2001-04-06 오석송 A guided tissue regeneration membrane
KR20010044624A (en) * 2001-03-12 2001-06-05 정재호 A process for preparing the scaffold and tissue engineered cartilage made from the scaffold
KR20030032420A (en) * 2001-10-18 2003-04-26 한국과학기술연구원 Porous Scaffold Made of Biodegradable Polymer for Reconstructing Damaged Ocular Tissue
KR20060091301A (en) * 2003-09-19 2006-08-18 각고호우징 게이오기주크 Composition for coating support for preparation of cell sheet, support for preparation of cell sheet and process for producing cell sheet
US20060246105A1 (en) * 2005-04-28 2006-11-02 Fred Molz Coatings on medical implants to guide soft tissue healing

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ROBERT D. LEBOEUF ET AL., THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 261, no. 27, 1986, pages 12586 - 12592 *

Also Published As

Publication number Publication date
WO2011081328A2 (en) 2011-07-07

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