WO2011023105A1 - Intravascular reconstructive stent - Google Patents

Intravascular reconstructive stent Download PDF

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Publication number
WO2011023105A1
WO2011023105A1 PCT/CN2010/076333 CN2010076333W WO2011023105A1 WO 2011023105 A1 WO2011023105 A1 WO 2011023105A1 CN 2010076333 W CN2010076333 W CN 2010076333W WO 2011023105 A1 WO2011023105 A1 WO 2011023105A1
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WO
Grant status
Application
Patent type
Prior art keywords
stent
laid
vascular
gold
item
Prior art date
Application number
PCT/CN2010/076333
Other languages
French (fr)
Chinese (zh)
Inventor
刘建民
罗七一
谢志永
李�雨
王森
李建军
金巧蓉
向勇刚
Original Assignee
微创医疗器械(上海)有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06Blood vessels
    • A61F2/07Stent-grafts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2002/823Stents, different from stent-grafts, adapted to cover an aneurysm
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0014Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
    • A61F2250/0023Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in porosity

Abstract

A vascular remodeling stent (10, 40, 50) has a mesh tubular structure which includes multiple pores formed by interleaved braiding several filaments (20). Every filament is continuous and the nodes (30) of the pores are moveable. The vascular remodeling stent is soft and flexible to pass through sinuous and tenuous brain blood vessels and reach the target diseased part, and is compliant with derious blood vessels to maintain the lumen passage in blood vessels. Furthermore, the stent includes pores with high density, and can remarkably change the blood stream in the aneurysm to stagnate the blood to form blood clots and organized thrombus.

Description

God, pipe supports this requirement to submit the patent office to 20,090,827,

20090 94688.0, in the first stent, the entire contents of which is incorporated by reference in the present. Wood field

The present device relates to an intravascular implant, in particular GOD blood vessel stent which may be implanted in the vascular vessel Haruyuki,, malformations, cases and the like. Background wood

Blood vessels, particularly blood vessels may locally born or, we force. And other diseases due to local weakness, or congenital factors in blood flow, weak gradually outward, a circular, circular, or the. There is bleeding in life-threatening disease in blood flow is not due to increased or other factors caused the rupture, the rupture has a high mortality rate caused by the board. It can be in different parts of Hugh's, and most often.

, Circuitous, degree bifurcated more sensitive to stimulation, lack of solid support and the like. Like most of the vessel branches, or the bifurcation site, mainly due to the blood flow Proficiency parts, namely formation of blood vessels ends, vessel elasticity, protrusions are formed, with the pro Beng stimulate vascular endothelial cell damage division, born success, is the basic cause of formation. Blood formation, the formation of full off resonance, promote vascular Beng, rupture.

The method of treatment typically includes a row. Surgical Hand wood, through the wood with gold Master head 2. Mediated intravascular Haruyuki, utilization of the spring (or micro gold or other material releasably curable break, etc.)

3. Endovascular treatment referral line stand Ueki. Since the surgical treatment of the line, where the high risk and high, the main method of endovascular treatment referral line gradually treatment line, which has a smaller, less safe, less patient pain, acceptance, hospitalized with, such as high-condition and ability .

Vascular puncture can be spring, early vascular Unimicro, the inner metal springs 5, while preventing blood flow. You can go to the roundabout of spring material and microtubules fibromatosis, and fill stop blood flow, but there are steps Japanese rupture of Van.

Line treatment is to reduce the rupture of all, the most fundamental way is 0 Hugh healing, heavy anatomy.

Hugh, vascular stents implanted stent re-treatment lines must each under special

1) micro loaded stent may stent circuitous soft foot, Qian, to the vessel

52) having a foot stent implantation, vascular circuitous

3) blood skill in the stent, with the stent covering often branched.

Prior to stent comprising a stent stenosis,

A spring endovascular stent implantation. However, vascular anatomy 0 circuitous, more than, the rigidity of the stent into a blood vessel it is.

Stent increase the stent system flexibility, often on a small gold-style, large. And have, effectively changing the stent method skill blood stream, and the stent is not present in the discount A5 vascular site. content

Above, this provides highly flexible and viable vascular stent, to the blood vessels through the thousand fold, the endovascular circuitous. Stent has a high density, it may be retained within the blood stream and is formed of a solid break.

The present blood vessel stent which may be implanted in the vascular vessel Haruyuki,, malformations, cases and the like. Hugh, the blood vessel stent

, Having a plurality of through multiple interlaced form. Wherein yes, the hole is successful. Refer to or.

The stent 0 15 ° 85 form an angle to the direction. .

3075. More 4560. The purpose of this engagement is a vascular stent having a support, having most of the same cis vascular within a blood vessel.

Greater than the density of the stent 5po es / m

The stent gold% 60% 30% 50% 35% 45% more

And planting row treatment site stent, the blood vessel stent having different portions of different gold.

Embodiment, the stent in the direction of gold. In, 30% gold 50%, in other positions, gold 12% 20%

Alternatively, the stent in the direction of gold. In, 50% gold 60%, at other locations, gold 12% 20%

The stent may be compared to 210.

The 8108, 2496, 3256 and more, the aim stent support and flexibility of the most balanced.

The shape may be different, for example rectangular, circular or other rounded.

Circular, straight of 0.2 0.01, 0.0250., 0.03 0.08 and more. Force rectangle, rectangular and 0.01 0.2, 0.5 0.02, 0.03 0.08 and more rectangular than 1,141. Inch of the object stent having bonding strength, can effectively eliminate the internal organs quite small

It is greater than 0 is generally straight. ) Shadow. 0.01 claim 3. Planting row treatment site and stent, may have a different. "" Refers to any of the sheep before Laid 2. Present, it may be used to support the blood vessel or within the stent to only within, the.

This advantageous effect in that

This highly flexible vascular stent,, to the blood vessels through the thousand fold, the circuitous passage intravascular blood vessel. Moreover, even a high density can be officials within the blood stream and is formed so solid-stranded break. With, as a force endothelial growth or support of high density, promote endometrial fast, while the inner lining of blood physical retention, so that more of intimal dissected.

Figure imgf000006_0001

The different illustrative schematic of another stent 5a, 5b present a stent of the present 6a 6d

Explanation

104050 intravascular stent

20

30 31 32 ,,,

4151

4252 other parts of the

4353

4454 branch 45, the blood vessel 55 normally rest mode

The following description of the present embodiment is different.

FIG 1-3, which present a highly flexible and viable vascular stent implant device 10. As shown in the blood vessel stent 10, 20 through which are formed alternately, having multiple. 20 also staggered holes, hole 30 is successful, or may be successful. Bracket

20 is formed in a direction toward the bracket, 15 ° 85. , 3075. More 4560. It can provide enough to / to support.

The vascular stent of the present, since power is 30 holes, 20 is not fixed to the upper, 20 may be mutually the same. Phase may stent 20 having sufficient activity can be the same or Japanese, but closer to the natural blood vessel, compliance and cis circuitous blood vessels, the same vessels.

, The density of the stent (i.e. the hole on sheep) is greater than 5po es / gold holder 12% 60%, 30% to 50%, more 35% 45%

8108 can be used, 2496, 3256 and more. Treatment plant and line parts of the stent may have different.

Control 3 0.01. Gold and density of the stent can be, inch, and so on. "" Refers to any of the sheep before Laid 2. Example 3 by 31 and 32 the same city.

4, the present stent has a soft and yieldable higher than the 2101 can be loaded into the 0.3 to 1.5 fold through the stent, vascular thousand.

5a and 5b, according to another embodiment, a vascular stent having a non-uniform lattice junction 40, 50, i.e. with the stent in different parts of different metal. Example, 43, 53, 41, 51 has a high gold, to change the maximum flow, while in other parts of the bracket 42, 52 has a low gold

To support the stent 45 often vessel, 55, may reduce the branch 44, 54 of the same material.

Embodiment, the gold 30% to 50%, in other positions, gold

12% 20%

Alternatively, the metal may be in the direction of the stent. On the gold 50% to 60%, in other positions, as shown in gold 12% 20% 6a 6d, may be a different shape, like rectangular embodiment, circular or circular.

In addition, planting apparatus can also be done in the (releasably springs, break, etc.) or a support to the material only in the

Inside, while the.

Claims

Claim
1. Vascular stents, which Laid wherein the vascular stent, having a plurality of through-multi interlaced form.
2. The stent of claim 1, wherein Laid the 5 yes.
3. The stent of claim 1, wherein Laid the aperture is successful.
4. Vascular stent according to any claim 1 to item 3, wherein Laid, 15 ° 85 forming the stent to the direction. .
105. Vascular stent of claim 4, wherein Laid which the stent 03075 to the forming direction. .
6. Blood vessel stent according to claim 5, wherein Laid which the stent is formed toward a direction.
04560.
7. Vascular stent according to any claim 1 to item 3, wherein Laid density of the stent is greater than 15 5po es / m 2.
8. Vascular stent according to any claim 1 to item 3, wherein Laid the stent 12% gold 60%
9. The stent of claim 8, wherein Laid the stent KIMHILL 30% 50%
2010. The stent of claim 9, wherein Laid the stent 35% gold 45%
11. The stent of claim 8, wherein Laid, planting row treatment site and stent, the blood vessel holder of different portions having different gold coating.
2512. Blood vessel stent according to claim 11, wherein Laid which the stent up of gold.
13. Blood vessel stent according to claim 12, wherein Laid thereof, the blood vessel stent covering 30% gold 50%, gold in other locations
12% 20% 14. Blood vessel stent according to claim 11, wherein Laid which the stent up of gold.
15. The stent of claim 14, wherein Laid, the blood vessel stent 50% 60% gold, gold in other locations
5 12% 20%
16. Vascular stent according to any claim 1 to item 3, wherein Laid the stent than 210
17. Vascular stent according to any claim 1 to item 3, wherein Laid the 8108
1018. The stent of claim 17, wherein Laid the
2496
19. The stent of claim 18, wherein Laid the
3256
20. Claim 13 intravascular stent of any item which Laid wherein, circular or 15.
twenty one. Vascular stent according to any claim 1 to item 3, wherein Laid the circular shape.
twenty two. The stent of claim 21, wherein Laid said straight 0.01 0.2
2023. The stent of claim 22, wherein Laid said straight 0.025 ~ 0.
twenty four. The stent of claim 23, wherein Laid said straight .08 0.03
25. Vascular stent according to any claim 1 to item 3, wherein Laid force of the rectangle 25.
26. The stent of claim 25, wherein Laid the rectangular ratio of 114
27. The stent of claim 26, wherein Laid the rectangle 0.01 0.2 28 0.01 0.2. The stent of claim 27, wherein Laid the rectangle 0.5 0.02, 0.025.
29. The stent of claim 28, wherein Laid the rectangle 0.03 0.08 0.03 0.08
30. Vascular stent according to any claim 1 to item 3, wherein Laid said 3 0.01
31. The stent of claim 30, wherein Laid thereof, planting row treatment site and stent, having different.
32. Vascular stent according to any claim 1 to item 3, wherein Laid said biocompatible material force gold and / or polymers.
33. Vascular stent according to any claim 1 to item 3, wherein Laid the stent or within the support.
ten
PCT/CN2010/076333 2009-08-27 2010-08-25 Intravascular reconstructive stent WO2011023105A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN 200910194688 CN101991477B (en) 2009-08-27 2009-08-27 Vascular reconstructive support frame
CN200910194688.0 2009-08-27

Publications (1)

Publication Number Publication Date
WO2011023105A1 true true WO2011023105A1 (en) 2011-03-03

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Application Number Title Priority Date Filing Date
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Country Status (2)

Country Link
CN (1) CN101991477B (en)
WO (1) WO2011023105A1 (en)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9050205B2 (en) 2004-05-25 2015-06-09 Covidien Lp Methods and apparatus for luminal stenting
US9114001B2 (en) 2012-10-30 2015-08-25 Covidien Lp Systems for attaining a predetermined porosity of a vascular device
US9125659B2 (en) 2004-05-25 2015-09-08 Covidien Lp Flexible vascular occluding device
US9157174B2 (en) 2013-02-05 2015-10-13 Covidien Lp Vascular device for aneurysm treatment and providing blood flow into a perforator vessel
US9320590B2 (en) 2006-02-22 2016-04-26 Covidien Lp Stents having radiopaque mesh
US9393021B2 (en) 2004-05-25 2016-07-19 Covidien Lp Flexible vascular occluding device
US9452070B2 (en) 2012-10-31 2016-09-27 Covidien Lp Methods and systems for increasing a density of a region of a vascular device
US9943427B2 (en) 2012-11-06 2018-04-17 Covidien Lp Shaped occluding devices and methods of using the same
US10004618B2 (en) 2004-05-25 2018-06-26 Covidien Lp Methods and apparatus for luminal stenting

Families Citing this family (4)

* Cited by examiner, † Cited by third party
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CN102499732A (en) 2011-10-19 2012-06-20 微创医疗器械(上海)有限公司 Intravascular implanted device bag and preparation method for implanted device
CN102764170B (en) * 2012-07-18 2015-09-16 吕文峰 An internal vascular stent composite functions
US9913740B2 (en) * 2012-10-25 2018-03-13 W. L. Gore & Associates, Inc. Stent with varying cross-section
CN104720941A (en) * 2013-12-20 2015-06-24 微创神通医疗科技(上海)有限公司 Vessel stent and production method thereof

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CN101002702A (en) * 2006-01-16 2007-07-25 上海康德莱企业发展集团有限公司 Braided blood vessel stent with external ring-net skirt
WO2007139699A2 (en) * 2006-05-24 2007-12-06 Chestnut Medical Technologies, Inc. Flexible vascular occluding device
US20080039933A1 (en) * 2001-07-09 2008-02-14 Surpass Medical Ltd. Implantable intraluminal device and method of using same in treating aneurysms
CN101234046A (en) * 2007-01-17 2008-08-06 Aga医药有限公司 Intravascular deliverable stent for reinforcement of vascular abnormalities
CN101732116A (en) * 2008-11-15 2010-06-16 微创医疗器械(上海)有限公司 Intravascular stent used for repairing lesion blood vessel

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080039933A1 (en) * 2001-07-09 2008-02-14 Surpass Medical Ltd. Implantable intraluminal device and method of using same in treating aneurysms
CN101002702A (en) * 2006-01-16 2007-07-25 上海康德莱企业发展集团有限公司 Braided blood vessel stent with external ring-net skirt
WO2007139699A2 (en) * 2006-05-24 2007-12-06 Chestnut Medical Technologies, Inc. Flexible vascular occluding device
CN101234046A (en) * 2007-01-17 2008-08-06 Aga医药有限公司 Intravascular deliverable stent for reinforcement of vascular abnormalities
CN101732116A (en) * 2008-11-15 2010-06-16 微创医疗器械(上海)有限公司 Intravascular stent used for repairing lesion blood vessel

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9393021B2 (en) 2004-05-25 2016-07-19 Covidien Lp Flexible vascular occluding device
US9855047B2 (en) 2004-05-25 2018-01-02 Covidien Lp Flexible vascular occluding device
US9125659B2 (en) 2004-05-25 2015-09-08 Covidien Lp Flexible vascular occluding device
US9801744B2 (en) 2004-05-25 2017-10-31 Covidien Lp Methods and apparatus for luminal stenting
US9295568B2 (en) 2004-05-25 2016-03-29 Covidien Lp Methods and apparatus for luminal stenting
US9050205B2 (en) 2004-05-25 2015-06-09 Covidien Lp Methods and apparatus for luminal stenting
US10004618B2 (en) 2004-05-25 2018-06-26 Covidien Lp Methods and apparatus for luminal stenting
US9320590B2 (en) 2006-02-22 2016-04-26 Covidien Lp Stents having radiopaque mesh
US9610181B2 (en) 2006-02-22 2017-04-04 Covidien Lp Stents having radiopaque mesh
US9301831B2 (en) 2012-10-30 2016-04-05 Covidien Lp Methods for attaining a predetermined porosity of a vascular device
US9114001B2 (en) 2012-10-30 2015-08-25 Covidien Lp Systems for attaining a predetermined porosity of a vascular device
US9907643B2 (en) 2012-10-30 2018-03-06 Covidien Lp Systems for attaining a predetermined porosity of a vascular device
US9452070B2 (en) 2012-10-31 2016-09-27 Covidien Lp Methods and systems for increasing a density of a region of a vascular device
US9943427B2 (en) 2012-11-06 2018-04-17 Covidien Lp Shaped occluding devices and methods of using the same
US9157174B2 (en) 2013-02-05 2015-10-13 Covidien Lp Vascular device for aneurysm treatment and providing blood flow into a perforator vessel
US9561122B2 (en) 2013-02-05 2017-02-07 Covidien Lp Vascular device for aneurysm treatment and providing blood flow into a perforator vessel

Also Published As

Publication number Publication date Type
CN101991477B (en) 2014-03-26 grant
CN101991477A (en) 2011-03-30 application

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