WO2011010279A1 - Device and method for assisting a cough - Google Patents

Device and method for assisting a cough Download PDF

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Publication number
WO2011010279A1
WO2011010279A1 PCT/IB2010/053292 IB2010053292W WO2011010279A1 WO 2011010279 A1 WO2011010279 A1 WO 2011010279A1 IB 2010053292 W IB2010053292 W IB 2010053292W WO 2011010279 A1 WO2011010279 A1 WO 2011010279A1
Authority
WO
WIPO (PCT)
Prior art keywords
oscillation
airflow
lung system
cough
pressure
Prior art date
Application number
PCT/IB2010/053292
Other languages
French (fr)
Inventor
Maarten Leonardus Christian Brand
Sheng Jin
Original Assignee
Koninklijke Philips Electronics N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninklijke Philips Electronics N.V. filed Critical Koninklijke Philips Electronics N.V.
Priority to EP10745002.5A priority Critical patent/EP2456494B1/en
Priority to CN201080037481.3A priority patent/CN102481426B/en
Priority to JP2012521144A priority patent/JP5785543B2/en
Priority to RU2012106663/14A priority patent/RU2543542C2/en
Priority to BR112012001413-7A priority patent/BR112012001413B1/en
Priority to US13/384,410 priority patent/US10300239B2/en
Publication of WO2011010279A1 publication Critical patent/WO2011010279A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/20—Valves specially adapted to medical respiratory devices
    • A61M16/201—Controlled valves
    • A61M16/202—Controlled valves electrically actuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H23/00—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H31/00—Artificial respiration or heart stimulation, e.g. heart massage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M16/0006—Accessories therefor, e.g. sensors, vibrators, negative pressure with means for creating vibrations in patients' airways
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/021—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes operated by electrical means
    • A61M16/022—Control means therefor
    • A61M16/024—Control means therefor including calculation means, e.g. using a processor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2201/00—Characteristics of apparatus not provided for in the preceding codes
    • A61H2201/50—Control means thereof
    • A61H2201/5007—Control means thereof computer controlled
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2201/00—Characteristics of apparatus not provided for in the preceding codes
    • A61H2201/50—Control means thereof
    • A61H2201/5058—Sensors or detectors
    • A61H2201/5071—Pressure sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/20—Valves specially adapted to medical respiratory devices
    • A61M16/201—Controlled valves
    • A61M16/202—Controlled valves electrically actuated
    • A61M16/203—Proportional
    • A61M16/204—Proportional used for inhalation control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/20—Valves specially adapted to medical respiratory devices
    • A61M16/201—Controlled valves
    • A61M16/202—Controlled valves electrically actuated
    • A61M16/203—Proportional
    • A61M16/205—Proportional used for exhalation control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0027—Accessories therefor, e.g. sensors, vibrators, negative pressure pressure meter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/003—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter
    • A61M2016/0033—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical
    • A61M2016/0036—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical in the breathing tube and used in both inspiratory and expiratory phase

Definitions

  • the invention relates to a device and a method for assisting a cough.
  • lung mucus an excessive volume of viscoelastic material, which is called lung mucus, may be built up in the lung of a patient. Excessive lung mucus is known to cause severe problems due to an increased chance of lung infections, declined lung function, reduced effect of inhaled medicine etc.
  • an oscillation device to assist a cough is provided for Cystic Fibrosis and Chronic Obstructive Pulmonary Disease patients in order to increase lung mucus clearance.
  • the oscillation can be air oscillation pressure transmitted to a lung through a mouth for causing the airways of a lung to oscillate.
  • the oscillation also can be mechanical oscillation pressure transmitted to a lung through the ribcage and muscles, like for example High Frequency Chest Wall Oscillations (HFCWO).
  • HFCWO High Frequency Chest Wall Oscillations
  • An object of this invention is to provide a device for effectively assisting a cough.
  • the device for assisting a cough, based on oscillation pressure comprises a controlling unit.
  • the oscillation pressure causes a periodic oscillation airflow in a lung system and the periodic oscillation airflow comprises an oscillation exhalation airflow and an oscillation inhalation airflow.
  • the controlling unit comprises:
  • a first determining unit for determining whether an inhalation of the lung system is complete, so as to control a valve which is to be closed for isolating the lung system from the external environment
  • a second determining unit for determining whether an internal air pressure in the lung system is larger than a pre-defined pressure threshold
  • a detecting unit for detecting the start of the oscillation exhalation airflow, so as to control the valve which is to be opened for starting a cough.
  • the advantage is that the device of the invention can assist a cough more effectively.
  • the invention also provides a method corresponding to the device for assisting a cough.
  • the invention further provides a computer program used in the method of assisting a cough. Detailed explanations and other aspects of the invention will be given below.
  • Fig. 1 schematically shows a device for assisting a cough according to an embodiment of the invention
  • Fig. 2 is a diagram for illustrating a correlation between the velocity of an exhalation airflow of a cough and time
  • Fig. 3 is a waveform for illustrating a correlation between the velocity of an oscillation airflow and time
  • Fig. 4 schematically shows a mechanical oscillation pressure applied to a lung system and an air pressure detected through a mouth according to an example of the invention
  • Fig. 5 schematically shows an air oscillation pressure applied to a lung system through a mouth and an air pressure detected through the mouth according to another example of the invention
  • Fig. 6 is a flow chart for illustrating a method of assisting a cough according to an embodiment of the invention.
  • the same reference numerals are used to denote similar parts throughout the Figures.
  • Fig. 1 schematically shows a device for assisting a cough according to an embodiment of the invention.
  • the device 10 is used for assisting a cough, based on an oscillation pressure.
  • the device 10 comprises a controlling unit 11, an oscillation unit 12 for oscillating a lung system to cause a periodic oscillation airflow in the lung system, and a valve 13 controlled by the controlling unit 11 , which valve is to be opened or closed for, respectively, connecting the lung system to the external environment through a mouth or isolating the lung system from the external environment.
  • the oscillation unit 12 may be integrated together with the controlling unit 11 and included in the device 10.
  • the oscillation unit 12 is an air oscillation pressure unit.
  • the air oscillation pressure provided by the oscillation unit 12 is transmitted to the lung system through a mouth for causing the airways of a lung system to oscillate.
  • the oscillation unit 12 may be separate from the device 10, and not integral with the controlling unit 11.
  • the oscillation unit 12 is a mechanical pressure oscillation unit.
  • the mechanical oscillation pressure is transmitted to the lung system through the ribcage and muscles, like for example High Frequency Chest Wall Oscillations (HFCWO).
  • HFCWO High Frequency Chest Wall Oscillations
  • the oscillation unit 12 generates an oscillation pressure (shown as OP in Fig. 1) to oscillate the airways of the lung system, and the oscillation pressure causes a periodic oscillation airflow in the airways of the lung system.
  • the periodic oscillation airflow comprises an oscillation exhalation airflow and an oscillation inhalation airflow.
  • the controlling unit 11 comprises a first determining unit 111 for determining whether an inhalation of the lung system is complete, so as to control the valve which is to be closed for isolating the lung system from the external environment, a second determining unit 112 for determining whether an internal air pressure (shown as IAP in Fig.
  • a detecting unit 113 for detecting the start of the oscillation exhalation airflow shown as OEA in Fig. 1
  • the valve 13 may be integrated with the controlling unit 11 so as to be opened or closed based on the controlling action by the controlling unit 11. If the valve 13 is controlled so as to be closed based on a closing signal (shown as CS in Fig. 1 ) from the first determining unit
  • the lung system is isolated from the external environment and the external air cannot be inhaled into the lung system; if the valve 13 is controlled so as to be opened based on an opening signal (shown as OS in Fig. 1) from the detecting unit 113, mucus and air (shown as A&M in Fig. 1) in the airways of the lung system can be coughed/exhaled to the external environment, and external air (shown as A in Fig. 1) can be inhaled into the airways of the lung system.
  • an opening signal shown as OS in Fig. 1
  • mucus and air shown as A&M in Fig. 1 in the airways of the lung system can be coughed/exhaled to the external environment
  • external air shown as A in Fig. 1
  • the pre-defined pressure threshold may be set by a user, and the pre-defined pressure threshold may be different for different people.
  • the first determining unit 111 may be intended to determine whether the inhalation of the lung system is complete when the velocity of an inhalation airflow (shown as VIA in Fig. 1) in the lung system is lower than a pre-defined velocity threshold.
  • the oscillation exhalation airflow is synchronous with the exhalation airflow of the cough at least at the beginning of the cough. At the beginning of the cough, the cough causes a peak exhalation airflow in the airways of the lung system.
  • the pre-defined velocity threshold may be set by a manufacturer of the device 10 or a user, and the velocity threshold can be zero or any other value near zero.
  • the inhalation airflow may comprise the inhalation airflow caused by the inhalation of the lung system only.
  • the inhalation airflow may comprise the inhalation airflow caused by the inhalation of the lung system and the oscillating inhalation airflow caused by the oscillation pressure.
  • the first determining unit 111 may comprise a sensor for collecting the velocity of inhalation air in airways of the lung system
  • the second determining unit may comprise a sensor for collecting the internal air pressure of the lung system.
  • the sensor of the first determining unit 111 may be integrated together with the sensor of the second determining unit 112.
  • Fig. 2 is a diagram for illustrating a correlation between the velocity of an exhalation airflow of a cough and time. At the beginning of a cough, for example, at 0.03 seconds, the velocity of the exhalation airflow is almost 10 1/s (litre/second).
  • Fig. 3 is a waveform for illustrating a correlation between the velocity of an oscillation airflow and time.
  • the oscillation pressure causes a periodic oscillation airflow in the airways of the lung system, and the oscillation exhalation airflow of the oscillation airflow and the oscillation inhalation airflow of the oscillation airflow periodically change.
  • the oscillation pressure causes an oscillation exhalation airflow (shown as OEA in Fig. 3) in the airways of the lung system
  • the oscillation pressure causes an oscillation inhalation airflow (shown as OIA in Fig. 3) in the airways of the lung system.
  • the period of the periodic oscillation airflow can be 0.1s, 0.2s, 0.3s etc.
  • the internal air pressure of the lung system is larger than the pre-defined pressure threshold, and the lung system is ready to cough; secondly, in a periodic oscillation airflow, an oscillation exhalation airflow starts; thirdly, the valve 13 is opened; fourthly, the lung system starts to cough and causes a peak exhalation airflow in the airways of the lung system at the beginning of the cough, for example, at 0.03s, and, synchronously, in the periodic oscillation airflow, an oscillation exhalation airflow starts.
  • Fig. 4 schematically shows a mechanical pressure oscillation (shown as MOP) applied to a lung system, and an air pressure (shown as AP) in the lung system is detected through a mouth according to an example of the invention.
  • Fig. 5 schematically shows an air oscillation pressure (shown as AOP) applied to a lung system through a mouth, and an air pressure (AP) in the lung system is detected through the mouth according to another embodiment of the invention.
  • AOP air oscillation pressure
  • AP air pressure
  • Fig. 6 is a flow chart for illustrating a method of assisting a cough according to an embodiment of the invention.
  • the method serves to assist a cough, based on an oscillation pressure, and the oscillation pressure causes a periodic oscillation airflow in the airways of a lung system.
  • the periodic oscillation airflow comprises an oscillation exhalation airflow and an oscillation inhalation airflow.
  • the method comprises the following steps.
  • a step is carried out to determine 62 whether an inhalation of the lung system is complete, so as to control a valve 13 which is to be closed for isolating the lung system from the external environment.
  • the determining step 62 is intended to determine whether the inhalation of the lung system is complete when the velocity of an inhalation airflow in the lung system is lower than a pre-defined velocity threshold.
  • a next step is carried out to determine 63 whether the internal air pressure in the lung system is larger than a pre-defined pressure threshold.
  • a following step is carried out to detect 64 the start of the oscillation exhalation airflow, so as to control the valve 13 which is to be opened for starting a cough.
  • the oscillation exhalation airflow is synchronous with the exhalation airflow of the cough, at least at the beginning of the cough.
  • the method further comprises a step of generating 61 the oscillation pressure to oscillate the lung system so as to cause the periodic oscillation airflow in the airways of the lung system.
  • the lung system is ready to cough; in the periodic oscillation airflow, if an oscillation exhalation airflow starts, the valve 13 is controlled to open; if the valve
  • the lung system starts to cough when an oscillation exhalation airflow starts according to the periodic oscillation airflow.
  • the determining step 62 may be intended to determine whether the inhalation of the lung system is complete when the velocity of an inhalation airflow in the lung system is lower than a pre-defined velocity threshold.
  • the oscillation exhalation airflow is synchronous with the exhalation airflow of the cough, at least at the beginning of the cough
  • the inhalation airflow may comprise the inhalation airflow caused by the inhalation of the lung system only.
  • the inhalation airflow may comprise the inhalation airflow caused by the inhalation of the lung system and the oscillating inhalation airflow caused by the oscillation pressure.
  • determining 62 whether an inhalation of the lung system is complete so as to control a valve (13) which is to be closed for isolating the lung system from the external environment, determining 63 whether an internal air pressure in the lung system is larger than a pre-defined pressure threshold, and
  • the computer program used in the method of assisting a cough further comprising a step of generating the oscillation pressure to oscillate the lung system, so as to cause the periodic oscillation airflow in the airways of the lung system.
  • the oscillation frequency corresponding to the oscillation pressure may be in a range of 10-20Hz.

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Abstract

The invention provides a device (11) for assisting a cough, based on an oscillation pressure. The oscillation pressure causes a periodic oscillation airflow in a lung system and the periodic oscillation airflow comprises an oscillation exhalation airflow and an oscillation inhalation airflow. The device (10) comprises a controlling unit (11), and the controlling unit (11) comprises: - a first determining unit (111) for determining whether an inhalation of the lung system is complete, so as to control a valve (13) which is to be closed for isolating the lung system from the external environment, - a second determining unit (112) for determining whether an internal air pressure in the lung system is larger than a pre-defined pressure threshold, and - a detecting unit (113) for detecting the start of the oscillation exhalation airflow, so as to control the valve (13) which is to be opened for starting a cough.

Description

DEVICE AND METHOD FOR ASSISTING A COUGH
FIELD OF THE INVENTION
The invention relates to a device and a method for assisting a cough.
BACKGROUND OF THE INVENTION
In some medical conditions, such as, Chronic Obstructive Pulmonary Disease
(COPD), Asthma, and Cystic Fibrosis (CF), an excessive volume of viscoelastic material, which is called lung mucus, may be built up in the lung of a patient. Excessive lung mucus is known to cause severe problems due to an increased chance of lung infections, declined lung function, reduced effect of inhaled medicine etc.
The removal of excessive lung mucus is therefore highly beneficial to the health status of a patient. Normally patients are instructed to cough in special ways (called directed cough) or breathe in special patterns (called Huffing), but both often do not result in the desired effect.
Currently, an oscillation device to assist a cough is provided for Cystic Fibrosis and Chronic Obstructive Pulmonary Disease patients in order to increase lung mucus clearance. The oscillation can be air oscillation pressure transmitted to a lung through a mouth for causing the airways of a lung to oscillate. The oscillation also can be mechanical oscillation pressure transmitted to a lung through the ribcage and muscles, like for example High Frequency Chest Wall Oscillations (HFCWO). However, based on the current oscillation device, when oscillation is generated in the airways of a lung, a periodic oscillation airflow is generated, and the direction of the periodic oscillation airflow may be different from the direction of cough (exhalation) airflow during a cough, which may impede the cough.
SUMMARY OF THE INVENTION
An object of this invention is to provide a device for effectively assisting a cough.
The device for assisting a cough, based on oscillation pressure, comprises a controlling unit. The oscillation pressure causes a periodic oscillation airflow in a lung system and the periodic oscillation airflow comprises an oscillation exhalation airflow and an oscillation inhalation airflow. The controlling unit comprises:
a first determining unit for determining whether an inhalation of the lung system is complete, so as to control a valve which is to be closed for isolating the lung system from the external environment,
a second determining unit for determining whether an internal air pressure in the lung system is larger than a pre-defined pressure threshold, and
a detecting unit for detecting the start of the oscillation exhalation airflow, so as to control the valve which is to be opened for starting a cough.
The advantage is that the device of the invention can assist a cough more effectively.
The invention also provides a method corresponding to the device for assisting a cough.
The invention further provides a computer program used in the method of assisting a cough. Detailed explanations and other aspects of the invention will be given below.
DESCRIPTION OF THE DRAWINGS
The above and other objects and features of the present invention will become more apparent from the following detailed description considered in connection with the accompanying drawings, in which:
Fig. 1 schematically shows a device for assisting a cough according to an embodiment of the invention;
Fig. 2 is a diagram for illustrating a correlation between the velocity of an exhalation airflow of a cough and time;
Fig. 3 is a waveform for illustrating a correlation between the velocity of an oscillation airflow and time; Fig. 4 schematically shows a mechanical oscillation pressure applied to a lung system and an air pressure detected through a mouth according to an example of the invention;
Fig. 5 schematically shows an air oscillation pressure applied to a lung system through a mouth and an air pressure detected through the mouth according to another example of the invention;
Fig. 6 is a flow chart for illustrating a method of assisting a cough according to an embodiment of the invention. The same reference numerals are used to denote similar parts throughout the Figures.
DETAILED DESCRIPTION
Fig. 1 schematically shows a device for assisting a cough according to an embodiment of the invention.
The device 10 is used for assisting a cough, based on an oscillation pressure. The device 10 comprises a controlling unit 11, an oscillation unit 12 for oscillating a lung system to cause a periodic oscillation airflow in the lung system, and a valve 13 controlled by the controlling unit 11 , which valve is to be opened or closed for, respectively, connecting the lung system to the external environment through a mouth or isolating the lung system from the external environment.
The oscillation unit 12 may be integrated together with the controlling unit 11 and included in the device 10. For example, the oscillation unit 12 is an air oscillation pressure unit. The air oscillation pressure provided by the oscillation unit 12 is transmitted to the lung system through a mouth for causing the airways of a lung system to oscillate.
Alternatively, the oscillation unit 12 may be separate from the device 10, and not integral with the controlling unit 11. For example, the oscillation unit 12 is a mechanical pressure oscillation unit. The mechanical oscillation pressure is transmitted to the lung system through the ribcage and muscles, like for example High Frequency Chest Wall Oscillations (HFCWO).
The oscillation unit 12 generates an oscillation pressure (shown as OP in Fig. 1) to oscillate the airways of the lung system, and the oscillation pressure causes a periodic oscillation airflow in the airways of the lung system. The periodic oscillation airflow comprises an oscillation exhalation airflow and an oscillation inhalation airflow. The controlling unit 11 comprises a first determining unit 111 for determining whether an inhalation of the lung system is complete, so as to control the valve which is to be closed for isolating the lung system from the external environment, a second determining unit 112 for determining whether an internal air pressure (shown as IAP in Fig. 1) in the lung system is larger than a pre-defined pressure threshold, and a detecting unit 113 for detecting the start of the oscillation exhalation airflow (shown as OEA in Fig. 1), so as to control the valve 13 which is to be opened for starting a cough.
The valve 13 may be integrated with the controlling unit 11 so as to be opened or closed based on the controlling action by the controlling unit 11. If the valve 13 is controlled so as to be closed based on a closing signal (shown as CS in Fig. 1 ) from the first determining unit
111, the lung system is isolated from the external environment and the external air cannot be inhaled into the lung system; if the valve 13 is controlled so as to be opened based on an opening signal (shown as OS in Fig. 1) from the detecting unit 113, mucus and air (shown as A&M in Fig. 1) in the airways of the lung system can be coughed/exhaled to the external environment, and external air (shown as A in Fig. 1) can be inhaled into the airways of the lung system.
When the internal air pressure of the lung system is larger than the
pre-defined pressure threshold, the lung system is ready to cough; if the detecting unit 113 detects the start of the oscillation exhalation airflow, the valve 13 is controlled so as to be opened; if the valve 13 is open, the lung system starts to cough when the oscillation exhalation airflow starts according to the periodic oscillation airflow. The pre-defined pressure threshold may be set by a user, and the pre-defined pressure threshold may be different for different people. The first determining unit 111 may be intended to determine whether the inhalation of the lung system is complete when the velocity of an inhalation airflow (shown as VIA in Fig. 1) in the lung system is lower than a pre-defined velocity threshold. The oscillation exhalation airflow is synchronous with the exhalation airflow of the cough at least at the beginning of the cough. At the beginning of the cough, the cough causes a peak exhalation airflow in the airways of the lung system. The pre-defined velocity threshold may be set by a manufacturer of the device 10 or a user, and the velocity threshold can be zero or any other value near zero.
The inhalation airflow may comprise the inhalation airflow caused by the inhalation of the lung system only. Alternatively, the inhalation airflow may comprise the inhalation airflow caused by the inhalation of the lung system and the oscillating inhalation airflow caused by the oscillation pressure.
The first determining unit 111 may comprise a sensor for collecting the velocity of inhalation air in airways of the lung system, and the second determining unit may comprise a sensor for collecting the internal air pressure of the lung system. Alternatively, the sensor of the first determining unit 111 may be integrated together with the sensor of the second determining unit 112. Fig. 2 is a diagram for illustrating a correlation between the velocity of an exhalation airflow of a cough and time. At the beginning of a cough, for example, at 0.03 seconds, the velocity of the exhalation airflow is almost 10 1/s (litre/second).
Fig. 3 is a waveform for illustrating a correlation between the velocity of an oscillation airflow and time. The oscillation pressure causes a periodic oscillation airflow in the airways of the lung system, and the oscillation exhalation airflow of the oscillation airflow and the oscillation inhalation airflow of the oscillation airflow periodically change. In the first 0.05s, the oscillation pressure causes an oscillation exhalation airflow (shown as OEA in Fig. 3) in the airways of the lung system, and in the next 0.03s, the oscillation pressure causes an oscillation inhalation airflow (shown as OIA in Fig. 3) in the airways of the lung system. The period of the periodic oscillation airflow can be 0.1s, 0.2s, 0.3s etc.
In an embodiment of the invention: firstly, the internal air pressure of the lung system is larger than the pre-defined pressure threshold, and the lung system is ready to cough; secondly, in a periodic oscillation airflow, an oscillation exhalation airflow starts; thirdly, the valve 13 is opened; fourthly, the lung system starts to cough and causes a peak exhalation airflow in the airways of the lung system at the beginning of the cough, for example, at 0.03s, and, synchronously, in the periodic oscillation airflow, an oscillation exhalation airflow starts. Fig. 4 schematically shows a mechanical pressure oscillation (shown as MOP) applied to a lung system, and an air pressure (shown as AP) in the lung system is detected through a mouth according to an example of the invention.
Fig. 5 schematically shows an air oscillation pressure (shown as AOP) applied to a lung system through a mouth, and an air pressure (AP) in the lung system is detected through the mouth according to another embodiment of the invention.
Fig. 6 is a flow chart for illustrating a method of assisting a cough according to an embodiment of the invention. The method serves to assist a cough, based on an oscillation pressure, and the oscillation pressure causes a periodic oscillation airflow in the airways of a lung system. The periodic oscillation airflow comprises an oscillation exhalation airflow and an oscillation inhalation airflow. The method comprises the following steps.
A step is carried out to determine 62 whether an inhalation of the lung system is complete, so as to control a valve 13 which is to be closed for isolating the lung system from the external environment. The determining step 62 is intended to determine whether the inhalation of the lung system is complete when the velocity of an inhalation airflow in the lung system is lower than a pre-defined velocity threshold. A next step is carried out to determine 63 whether the internal air pressure in the lung system is larger than a pre-defined pressure threshold.
A following step is carried out to detect 64 the start of the oscillation exhalation airflow, so as to control the valve 13 which is to be opened for starting a cough. The oscillation exhalation airflow is synchronous with the exhalation airflow of the cough, at least at the beginning of the cough.
The method further comprises a step of generating 61 the oscillation pressure to oscillate the lung system so as to cause the periodic oscillation airflow in the airways of the lung system.
When the internal air pressure of the lung system is larger than the
pre-defined pressure threshold, the lung system is ready to cough; in the periodic oscillation airflow, if an oscillation exhalation airflow starts, the valve 13 is controlled to open; if the valve
13 is open, the lung system starts to cough when an oscillation exhalation airflow starts according to the periodic oscillation airflow.
The determining step 62 may be intended to determine whether the inhalation of the lung system is complete when the velocity of an inhalation airflow in the lung system is lower than a pre-defined velocity threshold. The oscillation exhalation airflow is synchronous with the exhalation airflow of the cough, at least at the beginning of the cough
The inhalation airflow may comprise the inhalation airflow caused by the inhalation of the lung system only. Alternatively, the inhalation airflow may comprise the inhalation airflow caused by the inhalation of the lung system and the oscillating inhalation airflow caused by the oscillation pressure.
A computer program used in the method of assisting a cough, based on an oscillation pressure, wherein the oscillation pressure causes a periodic oscillation airflow in a lung system and the periodic oscillation airflow comprises an oscillation exhalation airflow and an oscillation inhalation airflow, the method comprising the steps of:
determining 62 whether an inhalation of the lung system is complete, so as to control a valve (13) which is to be closed for isolating the lung system from the external environment, determining 63 whether an internal air pressure in the lung system is larger than a pre-defined pressure threshold, and
detecting the start of the oscillation exhalation airflow, so as to control the valve which is to be opened for starting a cough.
The computer program used in the method of assisting a cough, the method further comprising a step of generating the oscillation pressure to oscillate the lung system, so as to cause the periodic oscillation airflow in the airways of the lung system. The oscillation frequency corresponding to the oscillation pressure may be in a range of 10-20Hz.
It should be noted that the above-mentioned embodiments illustrate rather than limit the invention and that those skilled in the art will be able to design alternative embodiments without departing from the scope of the appended claims. In the claims, any reference signs placed between parentheses shall not be construed as limiting the claim. The word "comprising" does not exclude the presence of elements or steps not listed in a claim or in the description. The word "a" or "an" preceding an element does not exclude the presence of a plurality of such elements. The invention can be implemented by a unit of hardware comprising several distinct elements and by a unit of a programmed computer. In the system claims enumerating several units, several of these units can be embodied by one and the same item of hardware or software. The use of the words first, second and third, et cetera, does not indicate any ordering. These words are to be interpreted as names.

Claims

CLAIMS:
1. A device (10) for assisting a cough, based on an oscillation pressure, wherein the oscillation pressure causes a periodic oscillation airflow in a lung system, and the periodic oscillation airflow comprises an oscillation exhalation airflow and an oscillation inhalation airflow, and the device (10) comprising a controlling unit (11) comprising:
a first determining unit (111) for determining whether an inhalation of the lung system is complete, so as to control a valve (13) which is to be closed for isolating the lung system from the external environment,
a second determining unit (112) for determining whether an internal air pressure in the lung system is larger than a pre-defined pressure threshold, and a detecting unit (113) for detecting the start of the oscillation exhalation airflow, so as to control the valve (13) which is to be opened for starting a cough.
2. The device as claimed in claim 1, wherein the first determining unit (111) is intended to determine whether the inhalation of the lung system is complete when the velocity of the inhalation airflow in the lung system is lower than a pre-defined velocity threshold.
3. The device as claimed in claim 1, further comprising an oscillation unit (12) for providing the oscillation pressure to oscillate the lung system, so as to cause the periodic oscillation airflow in the lung system.
4. A method of assisting a cough, based on an oscillation pressure, wherein the oscillation pressure causes a periodic oscillation airflow in a lung system, and the periodic oscillation airflow comprises an oscillation exhalation airflow and an oscillation inhalation airflow, and the method comprising the steps of: determining (62) whether an inhalation of the lung system is complete, so as to control a valve (13) which is to be closed for isolating the lung system from the external environment,
determining (63) whether an internal air pressure in the lung system is larger than a pre-defined pressure threshold, and
detecting (64) the start of the oscillation exhalation airflow, so as to control the valve (13) which is to be opened for starting a cough.
5. The method as claimed in claim 4, wherein the first determining step (62) is intended to determine whether the inhalation of the lung system is complete when the velocity of an inhalation airflow in the lung system is lower than a pre-defined velocity threshold.
6. The method as claimed in claim 4, further comprising a step of generating the oscillation pressure to oscillate the lung system, so as to cause the periodic oscillation airflow in the lung system.
7. A computer program used in a method of assisting a cough, based on an oscillation pressure, wherein the oscillation pressure causes a periodic oscillation airflow in a lung system and the periodic oscillation airflow comprises an oscillation exhalation airflow and an oscillation inhalation airflow, and the method comprising the steps of:
determining (62) whether an inhalation of the lung system is complete, so as to control a valve (13) which is to be closed for isolating the lung system from the external environment,
determining (63) whether an internal air pressure in the lung system is larger than a pre-defined pressure threshold, and
detecting the start of the oscillation exhalation airflow, so as to control the valve which is to be opened for starting a cough.
8. The computer program as claimed in claim 7, the method further comprising a step of generating the oscillation pressure to oscillate the lung system, so as to cause the periodic oscillation airflow in the lung system.
PCT/IB2010/053292 2009-07-24 2010-07-20 Device and method for assisting a cough WO2011010279A1 (en)

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EP10745002.5A EP2456494B1 (en) 2009-07-24 2010-07-20 Device and method for assisting a cough
CN201080037481.3A CN102481426B (en) 2009-07-24 2010-07-20 Device and method for assisting a cough
JP2012521144A JP5785543B2 (en) 2009-07-24 2010-07-20 Device and method for assisting cough
RU2012106663/14A RU2543542C2 (en) 2009-07-24 2010-07-20 Device and method for facilitating expectoration
BR112012001413-7A BR112012001413B1 (en) 2009-07-24 2010-07-20 device to help cough
US13/384,410 US10300239B2 (en) 2009-07-24 2010-07-20 Device and method for assisting a cough

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JP2013500052A (en) 2013-01-07
JP5785543B2 (en) 2015-09-30
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CN102481426B (en) 2015-01-14
RU2543542C2 (en) 2015-03-10
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US10300239B2 (en) 2019-05-28
EP2456494A1 (en) 2012-05-30

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