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Multi-density polymeric interbody spacer and method for fabrication thereof

Info

Publication number
WO2011008733A3
WO2011008733A3 PCT/US2010/041790 US2010041790W WO2011008733A3 WO 2011008733 A3 WO2011008733 A3 WO 2011008733A3 US 2010041790 W US2010041790 W US 2010041790W WO 2011008733 A3 WO2011008733 A3 WO 2011008733A3
Authority
WO
Grant status
Application
Patent type
Prior art keywords
density
region
polymeric
interbody
regions
Prior art date
Application number
PCT/US2010/041790
Other languages
French (fr)
Other versions
WO2011008733A2 (en )
Inventor
M.D. Richard J. Deslauriers
Joseph Jannetty
Eric Kolb
John A. Tomich
Naresh Akkarapaka
Original Assignee
Doctors Research Group, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE, IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C39/00Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor
    • B29C39/003Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor characterised by the choice of material
    • B29C39/006Monomers or prepolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/12Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L31/125Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L31/129Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix containing macromolecular fillers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/146Porous materials, e.g. foams or sponges
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE, IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C39/00Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor
    • B29C39/02Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor for making articles of definite length, i.e. discrete articles
    • B29C39/021Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor for making articles of definite length, i.e. discrete articles by casting in several steps
    • B29C39/025Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor for making articles of definite length, i.e. discrete articles by casting in several steps for making multilayered articles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE, IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C39/00Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor
    • B29C39/02Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor for making articles of definite length, i.e. discrete articles
    • B29C39/10Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor for making articles of definite length, i.e. discrete articles incorporating preformed parts or layers, e.g. casting around inserts or for coating articles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE, IN GENERAL
    • B29LINDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00Other particular articles
    • B29L2031/753Medical equipment; Accessories therefor
    • B29L2031/7532Artificial members, protheses

Abstract

A multi-density polymeric interbody spacer formed from biocompatible material for osteoconductivity includes multiple density regions of different porosity to provide both strength and osteoconductivity. An interface region is formed between the density regions to provide both direct adhesion and mechanical interlocking between the different density regions to increase the strength of the multi-density polymeric interbody spacer. A method for forming the multi-density polymeric interbody spacer includes curing a first density region to achieve a first target porosity. A second density region may then be molded to the first density region to achieve a second target porosity. A portion of the second density region partially flows into pores of the first density region, providing direct adhesion and mechanical interlocking between the first and second density regions.
PCT/US2010/041790 2009-07-14 2010-07-13 Multi-density polymeric interbody spacer and method for fabrication thereof WO2011008733A3 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
US12502635 US20110012280A1 (en) 2009-07-14 2009-07-14 Method for fabricating a multi-density polymeric interbody spacer
US12/502,597 2009-07-14
US12502597 US20110015743A1 (en) 2009-07-14 2009-07-14 Multi-density polymeric interbody spacer
US12/502,635 2009-07-14

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA 2767822 CA2767822A1 (en) 2009-07-14 2010-07-13 Multi-density polymeric interbody spacer and method for fabrication thereof
EP20100800407 EP2453937A2 (en) 2009-07-14 2010-07-13 Multi-density polymeric interbody spacer and method for fabrication thereof

Publications (2)

Publication Number Publication Date
WO2011008733A2 true WO2011008733A2 (en) 2011-01-20
WO2011008733A3 true true WO2011008733A3 (en) 2011-07-07

Family

ID=43450130

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2010/041790 WO2011008733A3 (en) 2009-07-14 2010-07-13 Multi-density polymeric interbody spacer and method for fabrication thereof

Country Status (3)

Country Link
CA (1) CA2767822A1 (en)
EP (1) EP2453937A2 (en)
WO (1) WO2011008733A3 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012063868A1 (en) 2010-11-10 2012-05-18 Hoya株式会社 Vertebral spacer
GB2500514B (en) * 2010-11-10 2015-07-22 Mitsubishi Materials Corp Vertebral body spacer
CN103239282A (en) * 2012-02-10 2013-08-14 北京爱康宜诚医疗器材股份有限公司 Vertebral body union internal fixation system

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5607474A (en) * 1992-02-14 1997-03-04 Board Of Regents, University Of Texas System Multi-phase bioerodible implant/carrier and method of manufacturing and using same
US5702449A (en) * 1995-06-07 1997-12-30 Danek Medical, Inc. Reinforced porous spinal implants
US6149688A (en) * 1995-06-07 2000-11-21 Surgical Dynamics, Inc. Artificial bone graft implant
US6482234B1 (en) * 2000-04-26 2002-11-19 Pearl Technology Holdings, Llc Prosthetic spinal disc
US20030004578A1 (en) * 2001-06-28 2003-01-02 Ethicon, Inc. Composite scaffold with post anchor for the repair and regeneration of tissue
US20040249462A1 (en) * 2003-06-06 2004-12-09 Shih-Shing Huang Artificial intervertebral disc flexibly oriented by spring-reinforced bellows
US20050228498A1 (en) * 2003-11-18 2005-10-13 Todd Andres Osteoconductive integrated spinal cage and method of making same
US20090043398A1 (en) * 2007-08-09 2009-02-12 Zimmer, Inc. Method of producing gradient articles by centrifugation molding or casting

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5607474A (en) * 1992-02-14 1997-03-04 Board Of Regents, University Of Texas System Multi-phase bioerodible implant/carrier and method of manufacturing and using same
US5702449A (en) * 1995-06-07 1997-12-30 Danek Medical, Inc. Reinforced porous spinal implants
US6149688A (en) * 1995-06-07 2000-11-21 Surgical Dynamics, Inc. Artificial bone graft implant
US6482234B1 (en) * 2000-04-26 2002-11-19 Pearl Technology Holdings, Llc Prosthetic spinal disc
US20030004578A1 (en) * 2001-06-28 2003-01-02 Ethicon, Inc. Composite scaffold with post anchor for the repair and regeneration of tissue
US20040249462A1 (en) * 2003-06-06 2004-12-09 Shih-Shing Huang Artificial intervertebral disc flexibly oriented by spring-reinforced bellows
US20050228498A1 (en) * 2003-11-18 2005-10-13 Todd Andres Osteoconductive integrated spinal cage and method of making same
US20090043398A1 (en) * 2007-08-09 2009-02-12 Zimmer, Inc. Method of producing gradient articles by centrifugation molding or casting

Also Published As

Publication number Publication date Type
WO2011008733A2 (en) 2011-01-20 application
EP2453937A2 (en) 2012-05-23 application
CA2767822A1 (en) 2011-01-20 application

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